Search Results
Results 651 - 700 of 2433
< 9 10 11 12 13 14 15 16 17 18 19 >
Chen Kuan-Chung - - 2012
Insulin-degrading enzyme (IDE) gene is one of the type 2 diabetes mellitus susceptibility genes specific to the Han Chinese population. IDE, a zinc-metalloendopeptidase, is a potential target for controlling insulin degradation. Potential lead compounds for IDE inhibition were identified from traditional Chinese medicine (TCM) through virtual screening and evaluation of ...
Atladóttir Hjördis Ósk - - 2012
OBJECTIVES:Results of animal studies suggest that maternal immune activation during pregnancy causes deficiencies in fetal neurodevelopment. Infectious disease is the most common path to maternal immune activation during pregnancy. The goal of this study was to determine the occurrence of common infections, febrile episodes, and use of antibiotics reported by ...
Chang Stanley - - 2012
A silver(I)-promoted intramolecular hemiacetal alkylation has been developed that converts readily available keto-chlorodiols into functionalized spiroacetals containing 5,5-, 5,6-, and 5,7-membered ring systems. The efficiency of this process is demonstrated in a concise total synthesis of the fungal metabolites cephalosporolides E and F.
Haydin Sertac - - 2012
Near-infrared spectroscopy (NIRS) is a noninvasive modality to monitor regional brain oxygenation (rSO(2) ). In this study, we aimed to investigate the correlation between cerebral rSO(2) and lactate, pump flow, hematocrit, pCO(2) , and mean blood pressure (MBP) during cardiopulmonary bypass (CPB). Between March and September 2011, 50 pediatric patients ...
Thorpe-Beeston Jg - - 2012
OBJECTIVE: To describe the maternal and fetal outcomes of pregnancies in women with cystic fibrosis. DESIGN: Retrospective study. SETTING: Single obstetric hospital and adult cystic fibrosis centre. METHODS: Retrospective case-note review of pregnant women with cystic fibrosis referred for antenatal care and delivery. MAIN OUTCOME MEASURES: Maternal and fetal outcomes, ...
Lewis Sue - - 2012
This research article on youth smoking in disadvantaged communities is the product of a qualitative study to understand the issues faced by young smokers - and those trying not to be smokers - in such communities. Environmental factors and peer influence are widely recognised influences on adolescents' take-up and continuation ...
Laplana Marina - - 2012
We tested bone marrow stromal cell antigen-2 (BST-2) gene variants rs3217318, a promoter 19bp insertion/deletion polymorphism, and rs10415893, a 3'UTR tagSNP, for association with human immunodeficiency virus type-1 (HIV-1) infection and disease progression. The study included 356 subjects exposed to HIV-1, 185 infected and 171 noninfected, and 188 controls. A ...
Pei Qi - - 2012
Aim:To investigate the influence of peroxisome proliferator-activated receptor γ2 (PPAR-γ2) gene polymorphism rs1801282 and protein tyrosine phosphatase receptor type D (PTPRD) gene polymorphism rs17584499 on the occurrence of type 2 diabetes and pioglitazone efficacy in a Chinese Han population.Methods:One hundred ninety seven type 2 diabetes patients and 212 healthy controls ...
Krizsan S J - - 2012
The objective of the present study was to compare digestion rates (k(d)) of NDF for different feeds estimated with the in situ method or derived from an automated gas in vitro system. A meta-analysis was conducted to evaluate how in situ derived k(d) of NDF related to in vivo digestibility ...
Savellano Mark D - - 2012
A novel pyropheophorbide-a (PPa) derivative, Ac-sPPp, was developed in our lab for targeted photodynamic therapy (PDT) and combination therapies. Its versatile peptide moiety, high water-solubility, amphiphilicity, and micellar aggregation allow efficient coupling to targeting moieties and convenient mixing with other therapeutics. Photosensitizer immunoconjugate (PIC) targeted PDT, using Ac-sPPp conjugated to ...
Guo Qiuju - - 2012
The unattached fraction of radon progeny (f(p)) is one of the most important factors for accurate evaluation of the effective dose from a unit of radon exposure, and it may vary greatly in different environments. For precise evaluation of the indoor radon exposure dose and the influence of unattached radon ...
Söderman Stefan C - - 2012
Dibromotetrachloroethane (C(2)Br(2)Cl(4)) is demonstrated as a halogenating reagent for the one-pot conversion of sulfones to alkenes by way of the Ramberg-Bäcklund rearrangement. Dibromotetrachloroethane successfully replaces known ozone depleting agents CCl(4), CBr(2)F(2) and C(2)Br(2)F(4). A formal synthesis of E-resveratrol is demonstrated using C(2)Br(2)Cl(4).
Halilov S V - - 2012
The tunneling of carriers in stratified superlattice systems is analyzed in terms of the constituent effective mass tensor. The focus is on the effects on the tunneling which are caused by the side regions of an intervening barrier. Depending on the covalency and work function in the constituent layers of ...
Bertossi Dario - - 2012
OBJECTIVE To present our experience in the use of fresh-frozen human bone allograft as an interpositional grafting material for sliding genioplasty to correct chin deformities. METHODS Ten patients underwent sliding genioplasty using morcellized and corticospongious fresh-frozen human bone. Four patients underwent orthognathic surgery associated with genioplasty. Six patient underwent genioplasty ...
Moromizato Shinsuke - - 2012
Cyclometalated iridium(III) complexes have received considerable attention and are important candidates for use as luminescent probes for cellular imaging because of their potential photophysical properties. We previously reported that fac-Ir(atpy)(3)4 (atpy = 2-(5'-amino-4'-tolyl)pyridine) containing three amino groups at the 5'-position of the atpy ligand shows a maximum red emission (at ...
Luo Jiaying - - 2012
SUMMARY AT A GLANCE: Two titration methods have been used to assess the pressure for long term CPAP treatment. We compared automatic titration with manual titration, the gold standard for determining CPAP pressure, and found that the pressure from automatic titration is consistently higher than the pressure derived from manual ...
Li Hong - - 2012
Background and Aim: Dementia is a serious disease that places undue burden on family care providers. This study aimed to investigate caring burden and associated factors of care providers for dementia patients in an urban-rural fringe area in China. Methods: A total of 197 dementia patients ≥65 years old were ...
Dalkas Georgios A - - 2012
The quest for small drug-like compounds that selectively inhibit the function of biological targets has always been a major focus in the pharmaceutical industry and in academia as well. High-throughput screening of compound libraries requires time, cost and resources. Therefore, the use of alternative methods is necessary for facilitating lead ...
Wenzel Jürgen J - - 2012
HEV seroprevalences of 0.3-53% were reported from industrialized countries. As these estimates may be influenced by the detection assays, this study compares 3 tests frequently used: (A) MP HEV IgG ELISA, (B) Axiom HEV IgG EIA and (C) Mikrogen recomLine HEV IgG. 200 sera from healthy and 30 from individuals ...
Gabelli J - - 2012
We review the first experiment on dynamic transport in a phase-coherent quantum conductor. In our discussion, we highlight the use of time-dependent transport as a means of gaining insight into charge relaxation on a mesoscopic scale. For this purpose, we studied the ac conductance of a model quantum conductor, i.e. ...
Del Vesco A P - - 2012
The aim of the present study was to evaluate the affect of acute heat stress on the production of mitochondrial reactive oxygen species (ROS), the gene expression of the avian uncoupling protein (avUCP) and glutathione peroxidase (GPX 7), and the activity of the enzyme glutathione peroxidase in the liver of ...
Marchais-Oberwinkler Sandrine - - 2012
Inhibition of 17β-HSD2 is an attractive mechanism for the treatment of osteoporosis. We report here the optimization of human 17β-HSD2 inhibitors in the 2,5-thiophene amide class varying the size of the linker (n equal 0 and 2) between the amide moiety and the phenyl group. While the ethylene linker did ...
Chen Wen-Liang - - 2012
A general and efficient palladium-catalyzed intermolecular direct C3 alkenylation of indoles using oxygen as the oxidant has been developed. The reaction is of complete regio- and stereoselectivity. All products are E-isomers at the C3-position, and no Z-isomers or 2-substituted product can be detected.
McCann Mark J - - 2012
SCOPE: There is evidence that a mammalian lignan, enterolactone (ENL), decreases the proliferation rate of prostate cancer cells, although previous studies have used concentrations difficult to achieve through dietary modification. We have therefore investigated the anti-proliferative effects of ENL in an in vitro model of prostate tumourigenesis at concentrations reported ...
Li Hailing - - 2012
A simple copper-catalyzed enantioselective synthesis of axially chiral chloroallenes from the propargylic dichlorides is reported, employing a catalytic amount of easily prepared SimplePhos ligand. Exclusive formation of the desired allenes was observed with good enantioselectivities (ee's 62-96%). Further transformations to trisubstituted allenes or terminal alkynes with a propargylic quaternary carbon ...
Rios Daniel - - 2012
Combined collision-induced dissociation mass spectrometry experiments with DFT and MP2 calculations were employed to elucidate the molecular structures and energetics of dissociation reactions of uranyl species containing acetone and diacetone alcohol ligands. It is shown that solutions containing diacetone alcohol ligands can produce species with more than five oxygen atoms ...
O'Brien Sheila F - - 2012
BACKGROUND: Various testing strategies may reduce the risk of Chagas disease transmission in nonendemic, low-prevalence countries. Results of the first year of selective testing of at-risk donors at Canadian Blood Services are reported. STUDY DESIGN AND METHODS: Since February 2009, platelets were not produced from at-risk donors. Since May 2010, ...
Sun Li-Na - - 2012
The taxonomic status of a bacterium strain DC-8T, isolated from activated sludge, was determined using a polyphasic taxonomic approach. The cells of strain DC-8T were Gram-negative, non-motile, non-spore-forming and rod-shaped. The isolate grew at temperature range of 10-40°C (optimum 30-35 °C), pH range of 5.0-10.0 (optimum 6.5-8.0) and NaCl 0-5 ...
Albrecht Lukasz - - 2012
Giving directions: Optically active dihydropyrans bearing three contiguous stereogenic centers can be efficiently prepared by the title reaction. High stereo- and regiocontrol can be achieved by employing a bifunctional H-bond-directing aminocatalyst.
Cao Ning - - 2012
Background/Aims: The aim of this study was to investigate the effect of netrin-1 on peritubular capillary (PTC) loss and hypoxia in 5/6 nephrectomized (Nx) rats. Methods: Male Sprague-Dawley rats were divided into three groups (n = 10 rats/group): sham-operated rats treated with control adenovirus; 5/6 Nx rats treated with control ...
Dikicier Sibel - - 2012
Abstract AbstractObjective: Restoration of lost dentition in the severely atrophic posterior maxilla has been successfully treated with various sinus augmentation techniques such as using bone grafts and bone substitutes are frequently used to enable placement of dental implants. The aim of this study was to evaluate whether sinus membrane elevation ...
Lee Shoo K - - 2012
Objective To assess the association between altitudes of neonatal intensive care units (NICU) and the rate of bronchopulmonary dysplasia (BPD) and BPD/death in very preterm infants.Study Design Data from infants born at <33 weeks' gestation admitted to Canadian Neonatal Network during 2008 and 2009 were analyzed. The associations between the altitude of ...
Valero Rosendo - - 2012
The OH + CO → H + CO(2) reaction is important in combustion, atmospheric, and interstellar chemistry. Whereas the direct reaction has been extensively studied both experimentally and theoretically, the reverse reaction has received relatively less attention. Here we carry out a quasiclassical trajectory study of the hyperthermal H + ...
Hales K E - - 2012
The use of wet distillers grains with solubles (WDGS) in feedlot diets has increased in the Southern Great Plains as a result of the growing ethanol industry. Nutrient balance and respiration calorimetry research evaluating the use of steam-flaked corn (SFC)-based diets in conjunction with WDGS is limited. Therefore, the effects ...
Schäffer Christian - - 2012
Addition of [Mo(2)(V)O(2)(μ-O)(μ-S)(aq)](2+) linker-type units to a solution/dynamic library containing tungstates results via the formation of the complementary pentagonal {(W)W(5)} units logically in the self-assembly of a mixed oxide/sulphide {W(VI)(72)Mo(V)(60)}-type Keplerate, thereby demonstrating the ability to tune the capsule's skeletal softness (the (μ-O)(2) and (μ-S)(2) scenarios are known) and providing ...
Yang Eric H - - 2012
A devastating complication of both native and prosthetic valvular infective endocarditis can involve periannular extension, which is associated with increased perioperative mortality and long-term adverse outcomes. Cardiac imaging, both noninvasive and invasive, is essential to accurately identify the extent and complexity of these infections to perform effective surgical interventional strategies. ...
Tang Yong - - 2012
Many studies using random dot kinematograms have indicated a global motion processing deficit originated from extrastriate cortex, specifically middle temporal area (MT) and media superior temporal area (MST), in patients with amblyopia. However, the nature of this deficit remains unclear. To explore whether the ability of motion integration is impaired ...
Katajavuori P - - 2012
A two-year-old Jack Russell terrier was presented for evaluation of chronic cough and exercise intolerance. Previous treatment with antibiotics and glucocorticoids had only partially ameliorated the clinical signs. During investigation, hypoxaemia, peripheral eosinophilia and an eosinophilic bronchoalveolar lavage fluid were noted. Thoracic radiographs revealed two ovoid clearly delineated soft-tissue opacities, ...
van den Broek Colette B M - - 2012
Background. Use of adjuvant chemotherapy for stage III colon cancer has increased since several trials have shown the beneficial effect on survival. In this population-based study we show time trends in the administration and costs of chemotherapy and relative survival of patients with stage III colon cancer. Methods. All patients ...
García Bocanegra Ignacio - - 2012
Abstract Seroprevalences of Toxoplasma gondii antibodies were assessed using a commercial indirect ELISA in 1501 domestic ruminants in southern Spain. Antibodies against T. gondii were detected in 420 (83.3%) of 504 cattle, 248 (49.3%) of 503 sheep and 124 (25.1%) of 494 goats. The herd seroprevalence was 100% (72/72), 84.7% ...
Xing Na - - 2012
Two new oxomolybdenum(vi) complexes [(TpMoO(2))(2)(μ-O)]·H(2)O () and (Tp(4-I)MoO(2))(2)(μ-O) () were synthesized and characterized by elemental analysis, IR spectra, UV-Vis spectroscopy, powder X-ray diffraction, single-crystal X-ray diffraction and thermogravimetric analyses (TG). In addition, the catalytic performances of complexes and were studied firstly on the oxidation reaction of cyclohexane at room temperature.
Santiago Diana - - 2012
An effort to electrochemically develop smaller and well dispersed catalytic materials on high surface area carbon supports is required for improved fuel cell performance. A high surface area carbon material of interest is carbon nano-onions (CNOs), also known as multilayer fullerenes. The most convenient synthetic method for CNOs is by ...
Schreiber Daniel K - - 2012
A sample preparation method is described for enabling direct correlation of site-specific plan-view and cross-sectional transmission electron microscopy (TEM) analysis of individual nanostructures by employing a dual-beam focused-ion beam (FIB) microscope. This technique is demonstrated using Si nanowires dispersed on a TEM sample support (lacey carbon or Si-nitride). Individual nanowires ...
Hall Louise - - 2012
ABSTRACT Background: Cognitive stimulation therapy (CST) is an evidence-based psychosocial intervention for people with dementia consisting of 14 group sessions aiming to stimulate various areas of cognition. This study examined the effects of CST on specific cognitive domains and explored the neuropsychological processes underpinning any effects. Methods: A total of ...
Reeder Jason P - - 2012
For cases requiring both a bone marrow aspirate and core biopsy, using the same needle and site (i.e., a combined technique) can decrease time, expense, and discomfort compared with the independent (direct) collection of each specimen. The benefits of the combined approach should not be achieved at the expense of ...
Meyer Sebastian - - 2012
Biochar application to agricultural soils can change the surface albedo which could counteract the climate mitigation benefit of biochar systems. However, the size of this impact has not yet been quantified. Based on empirical albedo measurements and literature data of arable soils mixed with biochar, a model for annual vegetation ...
Shi Zhiwei - - 2012
We have investigated the selective photoactivated room temperature chemical vapor deposition (CVD) of aluminum (Al) on functionalized self-assembled monolayers adsorbed on Au. The CVD precursor employed is trimethyl aluminum (TMA). Using a deuterium arc lamp we demonstrate that the Al film growth rate is approximately twice that observed for non-photoactivated ...
Leung Jackie - - 2012
PURPOSE: To compare measurements of blood flow velocity (BFV) and BFV changes in the middle cerebral arteries (MCA) acquired from phase contrast magnetic resonance angiography (PCMRA) and transcranial Doppler ultrasound (TCD) during controlled manipulation of end-tidal partial pressure of carbon dioxide (PETCO(2) ). MATERIALS AND METHODS: In vivo TCD and ...
Salitroš Ivan - - 2012
Three new Prussian blue analogues, heptanuclear mixed-valence iron complexes of the type [Fe(II)(CN)(6){Fe(III)(1(-2H))}(6)]Cl(2)·nH(2)O, were synthesized and structurally and spectrally characterized, and their magnetic properties were investigated (1(-2H) corresponds to doubly deprotoned Schiff-base pentadentate ligands 1a, N,N'-bis(2-hydroxybenzylidene)-1,5-diamino-3-azapentane, 1b, N,N'-bis(3-ethoxy-2-hydroxybenzylidene)-1,7-diamino-4-azaheptane, or 1c, N,N'-bis(3-methoxy-2-hydroxybenzylidene)-1,6-diamino-3-azahexane). These compounds were formed by assembling the [Fe(CN)(6)](4-) building ...
Lambeek Af - - 2012
Please cite this paper as: Lambeek A, De Hundt M, Vlemmix F, Akerboom B, Bais J, Papatsonis D, Mol B, Kok M. Risk of developmental dysplasia of the hip in breech presentation: the effect of successful external cephalic version. BJOG 2012; DOI: 10.1111/1471-0528.12013. Objective  To evaluate the effect of successful ...
< 9 10 11 12 13 14 15 16 17 18 19 >