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Results 601 - 650 of 2432
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Wang Weihong - - 2012
Six new (1, 2, and 5-8) and three known (3, 4, and 9) butenolide metabolites were isolated from the tunicate Pseudodistoma antinboja by activity-guided fractionations. The structures were elucidated by combined NMR and MS spectroscopic methods. These compounds were evaluated for their antibacterial activity, and most of them exhibited moderate ...
Li Tingting - - 2012
Ag/SmVO(4) composite photocatalysts were synthesized and characterized by BET, XRD, Raman, SEM, TEM, XPS and DRS techniques. Their photocatalytic activities were determined by oxidative decomposition of RhB in aqueous solution under visible-light irradiation. The charge separation efficiency was evaluated by the photocurrent-time and •OH-trapping experiments. The results revealed that the ...
Atkins J A - - 2012
A single ovulation, reciprocal embryo transfer study was used to investigate effects of oocyte competence and maternal environment on pregnancy establishment and maintenance in beef cows. Estrous cycles were synchronized in suckled beef cows and embryo donors were inseminated on d 0 (n = 810). Cows were classified on d ...
Ernst Lena H - - 2012
An approach bias for alcohol stimuli (i.e. faster approach than avoidance reactions) might facilitate relapses in alcohol dependence. Neurobiological models suggest hypersensitivity in the reward system [inter alia nucleus accumbens and orbitofrontal cortex (OFC)] to cause pathologically enhanced approach impulses towards alcohol stimuli. At the same time, in alcohol dependence, ...
Park Shin Hae - - 2012
Purpose: To determine the association of single nucleotide polymorphisms (SNPs) in the promoter region of the lumican (LUM) gene with high myopic Korean patients. Methods: Genomic DNA samples were obtained from 128 unrelated Korean patients with high myopia who had refractive errors ≤ -9.25 and axial lengths ≥ 26.5 mm in ...
Rath Detlef - - 2012
Pre-selection of spermatozoa based on the relative DNA difference between X- and Y- chromosome bearing populations by flow cytometry is an established method that has recently been introduced into commercial cattle production. Although several important improvements have increased the sort efficiency, the fertilizing ability of sexed spermatozoa based on offspring ...
Sales M O - - 2012
In this paper we study a one-dimensional ternary harmonic chain with the mass distribution constructed from an Ornstein-Uhlenbeck process. We generate a ternary mass disordered distribution by generating the correlated Ornstein-Uhlenbeck process and mapping it into a sequence of three different values. The probability of each value is controlled by ...
Wallys Jens - - 2012
We show that the photoluminescence intensity of GaN and InGaN nanowires in electrolytes sensitively responds to variations of the pH value and the applied bias. The realization of an electrochemical working point allows pH detection with a resolution better than 0.05 pH. The observed effects are attributed to bias-dependent nonradiative ...
Wolff Margaret - - 2012
BACKGROUND:Neonatal hyperbilirubinemia is a common reason for neonates to present to the emergency department (ED). Although clinical practice guidelines provide recommendations for evaluation and therapy, few studies have evaluated ways to apply them effectively in the ED setting. The primary objective of this study was to compare time to phototherapy ...
Sukumar Poornima - - 2012
A wide variety of microorganisms known to produce auxin and auxin precursors form beneficial relationships with plants and alter host root development. Moreover other signals produced by microorganisms affect auxin pathways in host plants. The precise role of auxin and auxin signaling pathways in modulating plant-microbe interactions, however, is unknown. ...
Fűlöpová Veronika - - 2012
Solid-phase synthesis of 3,4-dihydro-benzo[e][1,4]diazepin-5-ones with three diversity positions is described. Various primary amines were used as the starting material and immobilized on the polystyrene resin equipped with different acid-labile linkers. Polymer supported amines were converted to -aminoketones with the use of their sulfonylation with the p-nitrobenzensulfonylchoride and subsequent alkylation with ...
Chevrier Inès - - 2012
Complexes with silver ions have great potential for applications in medicine. Appropriate bidentate ligands, binding to silver ions, are able to generate coordination polymers as well as molecular entities as a function of ligand flexibility, conformation and length. Here we present the continuation of our previous studies in this field ...
Chen Shanliang - - 2012
This study comparatively evaluates the characteristics of glutaraldehyde-treated acellular bovine and donkey pericardium using histological and electronic microscopic observation techniques, shrinkage temperature, and mechanical properties, as well as determining calcium and phosphorus content at 4 and 8 weeks after the subcutaneous implantation of donkey and bovine pericardium in Wistar rats. ...
Roque Edelín - - 2012
The B-class of MADS-box genes has been studied in a wide range of plant species, but it has remained largely uncharacterized in legumes. Here we investigate the evolutionary fate of the duplicated AP3-like genes of a legume species. To gain insight into the extent to which B-class MADS-box gene functions ...
Sun Tao - - 2012
Interfaces usually impede heat transfer in heterogeneous structures. Recent experiments show that van der Waals (vdW) interactions can significantly enhance thermal conductivity parallel to the interface of a bundle of nanoribbons compared to a single layer of freestanding nanoribbon. In this paper, by simulating heat transfer in nanostructures based on ...
Shin Heon-Sub - - 2012
Crataegus pinnatifida has a long history of use in traditional oriental herbal medicine to stimulating digestion and improving blood circulation. Based on nutrition of hair, the present study was conducted to assess the effect of C. pinnatifida extract on hair growth using mouse model and its mechanisms of action. The ...
Ardigò Diego - - 2012
Background: The paper presents a post-hoc analysis of the intensity of dyslipidaemia care operated in the first 2 years of Multiple-Intervention-in-type-2-Diabetes.ITaly (MIND.IT) study.Design and methods: MIND.IT is a multicentric, randomized, two-parallel arm trial involving 1461 type 2 diabetic patients at high cardiovascular (CV) risk. The study compares the usual care ...
Treuner-Lange Anke - - 2012
Accurate positioning of the division site is essential to generate appropriately-sized daughter cells with the correct chromosome number. In bacteria, division generally depends on assembly of the tubulin homologue FtsZ into the Z-ring at the division site. Here, we show that lack of the ParA-like protein PomZ in M. xanthus ...
Wang Ya - - 2012
BTF3, which was originally recognized as a basal transcription factor, has been known to be involved in transcription initiation, translational regulation, and protein localization in many eukaryotic organisms. However, its function remains largely unknown in plant species. In the present study, we analyzed a BTF3-related sequence in Oryza sativa L. ...
Patel Anisha N - - 2012
Major new insights on electrochemical processes at graphite electrodes are reported, through extensive investigations of two of the most studied redox couples, Fe(CN)64-/3- and Ru(NH3)63+/2+. Experiments have been carried out on 5 different grades of highly orientated pyrolytic graphite (HOPG) that vary in step edge height and surface coverage. Significantly, ...
Won Tae Hyung - - 2012
Nine new compounds, tris-aromatic furanones (1, 2, 3a, 3b, and 4) and related bis-aromatic diesters (5a, 5b, 6a, and 6b), are described from the ascidian Synoicum sp. collected off the coast of Chuja-do, Korea. The structures of these compounds, designated as cadiolides E and G-I (1-4) and synoilides A and ...
Swaminathan Akhilesh - - 2012
BACKGROUND: There is a negative glucose gradient between the capillary and venous systems, produced by glucose uptake into peripheral tissues. This gradient is augmented by oral glucose ingestion in healthy volunteers; thus prandial status may impact on capillary glucose meter performance. Our primary aim was to investigate whether the (capillary-venous ...
Berger T - - 2012
Flotillin microdomains, specialized lipid raft domains in cell membranes, serve as physical platforms for many different molecules important in crucial intracellular signaling pathways. Flotillin-2 (Flot2), together with flotillin-1, is a marker for lipid raft microdomains distinct from caveolar lipid rafts, and has been implicated in the progression of cancer and ...
Mizuno T - - 2012
Mitral valve repair under cardiopulmonary bypass was performed in three dogs with clinical signs associated with mitral regurgitation that were not controlled by medication. Mitral valve repair comprised circumferential annuloplasty and chordal replacement with expanded polytetrafluoroethylene. One dog died 2 years after surgery because of severe mitral regurgitation resulting from partial ...
Antony Benny - - 2012
OBJECTIVE: Obesity is characterised by hyperinsulinemia, which is associated with diabetes, hypertension and coronary heart disease. The aim of this study was to determine if body fat and muscle measures predict the natural increase in leptin over 2.6 years in older adults. METHODS: 190 subjects (50% females) aged between 50 ...
Wood Douglas E - - 2012
Cardiothoracic surgery is undergoing major changes related to evolving technology, changes in the educational paradigm and evolution of health care policy. Many see these changes as a threat to the stature and viability of cardiothoracic surgery. However, these changes create tremendous opportunity to broaden our skills and scope of practice, ...
Tagliaferri Salvatore - - 2012
Abstract Background: Over the last 30 years, a great increase in the application of technologies in public health, with an undisputed impact on both the effectiveness of performance and the investment and management costs, has occurred. This evidence has induced the development of assessment tools to clarify the relationships among ...
Madsen Andreas Stahl - - 2012
Thymine intermediate 17 has been synthesized on a multigram scale (50 g, 70 mmol) from starting sugar 1 in fifteen steps in an overall yield of 73%, with only five purification steps. The key thymine intermediate 18 was obtained from 17 in a single step in 96% yield, whereas the ...
Bodkin Jennifer Victoria - - 2012
Sensory neurons play important roles in many disorders, including inflammatory diseases such as sepsis. Sepsis is a potentially lethal systemic inflammatory reaction to a local bacterial infection, affecting thousands of patients annually. Although associated with a high mortality rate, sepsis outcome depends on the severity of systemic inflammation, which can ...
Kiefte-de Jong Jessica C - - 2012
OBJECTIVE:To assess whether timing of introduction of fish and the amount of fish consumption in infancy were associated with asthmalike symptoms at preschool age.METHODS:This study was embedded in the Generation R study (a population-based birth cohort in Rotterdam, Netherlands). At the age of 12 and 14 months, timing of introduction ...
Chahal Dev S - - 2012
Plant-based extracts present a large source of natural immune modulators, many of which have been used in traditional medicine for centuries. Recent research efforts have identified plant extracts as potential modulators of Toll-like receptors (TLRs), the first responders in immunological defenses in normal and disease conditions. This review aims to ...
Preira P - - 2012
The deformability of circulating leukocytes plays an important role in the physiopathology of several diseases like sepsis or acute respiratory distress syndrome (ARDS). We present here a microfluidic method for the passive testing, sorting and separating of non-adherent cell populations by deformability. It consists of microfluidic sieves in series with ...
Peng Hui - - 2012
Angiostrongylus cantonensi can induce central nervous system (CNS) injury and cause human eosinophilic meningitis. The CNS has been found to have high expression of IL-33 which promotes the pathogenesis of Th2-related disease. Given the predominantly type 2 response induced by A. cantonensis-infected mice and human, it is likely that IL-33 ...
Hoebers Loes P - - 2012
AIMS: To evaluate the impact of multivessel disease (MVD) with and without a chronic total occlusion (CTO) on early and late mortality in ST-elevation myocardial infarction (STEMI) patients with and without cardiogenic shock (CS). METHODS AND RESULTS: A total of 5018 STEMI patients were treated with primary percutaneous coronary intervention ...
Hisabori Toru - - 2012
<b>Significance</b>: Regulation of the activity of the chloroplast ATP synthase is largely accomplished by the chloroplast thioredoxin system, the main redox regulation system in chloroplasts, which is directly coupled to the photosynthetic reaction. We review the current understanding of the redox regulation system of the chloroplast ATP synthase. <b>Recent Advances</b>: ...
Corcuera Leyre - - 2012
We studied the intraspecific variability of maritime pine in a set of morphological and physiological traits: soil-to-leaf hydraulic conductance, intrinsic water-use efficiency (WUE, estimated by carbon isotope composition, δ(13)C), root morphology, xylem anatomy, growth and carbon allocation patterns. The data were collected from Pinus pinaster Aiton seedlings (25 half-sib families ...
Stathis P - - 2012
BACKGROUND AND PURPOSE: Nocebo refers to adverse events (AEs) generated by patient's negative expectations that medical treatment will likely harm instead of heal and can be assessed in placebo-controlled randomized controlled trials (RCTs). We examined AEs following placebo administration in RCTs for Parkinson's disease (PD). METHODS: After a systematic Medline ...
van Gameren-Oosterom Helma B M - - 2012
OBJECTIVE:Prevalence of overweight in children is increasing, causing various health problems. This study aims to establish growth references for weight and to assess the prevalence rates of overweight and obesity in a nationwide sample of Dutch children with Down syndrome (DS), taking into account the influence of comorbidity.METHODS:In 2009, longitudinal ...
Oksay T - - 2012
Wireless devices have become part of everyday life and mostly located near reproductive organs while they are in use. The present study was designed to determine the possible protective effects of melatonin on oxidative stress-dependent testis injury induced by 2.45-GHz electromagnetic radiation (EMR). Thirty-two rats were equally divided into four ...
Periasamy Vaiyapuri Subbarayan - - 2012
Tea polyphenols (TPP) have potent antioxidant and anticancer properties, particularly in patients undergoing radiation or chemotherapy. However, few studies have been conducted on treatments using a combination of TPP and the conventional chemical anti-cancer drug cisplatin (CP). This study was designed to investigate the mechanism of the cytotoxicity of total ...
Shah Dipen M - - 2012
An efficient way to rapidly generate protein-ligand co-structures based on solution-NMR using sparse NOE data combined with selective isotope labeling is presented. A docked model of the 27 kDa N-terminal ATPase domain of Hsp90 bound to a small molecule ligand was generated using only 21 intermolecular NOEs which uniquely defined ...
Felten A - - 2012
We have recently identified apoptosis-antagonizing transcription factor (AATF), tumor-susceptibility gene 101 (TSG101) and zipper-interacting protein kinase (ZIPK) as novel coactivators of the androgen receptor (AR). The mechanisms of coactivation remained obscure, however. Here we investigated the interplay and interdependence between these coactivators and the AR using the endogenous prostate specific ...
Avila-Stagno J - - 2012
Two experiments were conducted to evaluate the effects of increasing concentrations of glycerol in concentrate diets on total tract digestibility, methane (CH4) emissions, growth, fatty acid profiles and carcass traits of lambs. In both experiments, the control diet contained 57% barley grain, 14.5% wheat dried distillers grain with solubles (WDDGS), ...
Cordente Antonio G - - 2012
Acetic acid, a byproduct formed during yeast alcoholic fermentation, is the main component of volatile acidity (VA). When present in high concentrations in wine, acetic acid imparts an undesirable 'vinegary' character that results in a significant reduction in quality and sales. Previously, it has been shown that saké yeast strains ...
Bastami Salumeh - - 2012
Most patients with advanced cancer experience severe pain and are often treated with opiates. Cancer patients are especially susceptible to opportunistic infections due to treatment with immunosuppressive and cytostatic drugs. Since opiates have been demonstrated to have immunomodulatory effects, it is of clinical importance to evaluate potential differences between commonly ...
Chen Kuan-Chung - - 2012
Insulin-degrading enzyme (IDE) gene is one of the type 2 diabetes mellitus susceptibility genes specific to the Han Chinese population. IDE, a zinc-metalloendopeptidase, is a potential target for controlling insulin degradation. Potential lead compounds for IDE inhibition were identified from traditional Chinese medicine (TCM) through virtual screening and evaluation of ...
Atladóttir Hjördis Ósk - - 2012
OBJECTIVES:Results of animal studies suggest that maternal immune activation during pregnancy causes deficiencies in fetal neurodevelopment. Infectious disease is the most common path to maternal immune activation during pregnancy. The goal of this study was to determine the occurrence of common infections, febrile episodes, and use of antibiotics reported by ...
Chang Stanley - - 2012
A silver(I)-promoted intramolecular hemiacetal alkylation has been developed that converts readily available keto-chlorodiols into functionalized spiroacetals containing 5,5-, 5,6-, and 5,7-membered ring systems. The efficiency of this process is demonstrated in a concise total synthesis of the fungal metabolites cephalosporolides E and F.
Haydin Sertac - - 2012
Near-infrared spectroscopy (NIRS) is a noninvasive modality to monitor regional brain oxygenation (rSO(2) ). In this study, we aimed to investigate the correlation between cerebral rSO(2) and lactate, pump flow, hematocrit, pCO(2) , and mean blood pressure (MBP) during cardiopulmonary bypass (CPB). Between March and September 2011, 50 pediatric patients ...
Thorpe-Beeston Jg - - 2012
OBJECTIVE: To describe the maternal and fetal outcomes of pregnancies in women with cystic fibrosis. DESIGN: Retrospective study. SETTING: Single obstetric hospital and adult cystic fibrosis centre. METHODS: Retrospective case-note review of pregnant women with cystic fibrosis referred for antenatal care and delivery. MAIN OUTCOME MEASURES: Maternal and fetal outcomes, ...
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