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Brownell Celia A CA University of Pittsburgh, PA, USA. - - 2013
To examine early developments in other-oriented resource sharing, fifty-one 18- and 24-month-old children were administered 6 tasks with toys or food that could be shared with an adult playmate who had none. On each task the playmate communicated her desire for the items in a series of progressively more explicit ...
Shin Heon-Sub - - 2012
Crataegus pinnatifida has a long history of use in traditional oriental herbal medicine to stimulating digestion and improving blood circulation. Based on nutrition of hair, the present study was conducted to assess the effect of C. pinnatifida extract on hair growth using mouse model and its mechanisms of action. The ...
Ardigò Diego - - 2012
Background: The paper presents a post-hoc analysis of the intensity of dyslipidaemia care operated in the first 2 years of Multiple-Intervention-in-type-2-Diabetes.ITaly (MIND.IT) study.Design and methods: MIND.IT is a multicentric, randomized, two-parallel arm trial involving 1461 type 2 diabetic patients at high cardiovascular (CV) risk. The study compares the usual care ...
Treuner-Lange Anke - - 2012
Accurate positioning of the division site is essential to generate appropriately-sized daughter cells with the correct chromosome number. In bacteria, division generally depends on assembly of the tubulin homologue FtsZ into the Z-ring at the division site. Here, we show that lack of the ParA-like protein PomZ in M. xanthus ...
Wang Ya - - 2012
BTF3, which was originally recognized as a basal transcription factor, has been known to be involved in transcription initiation, translational regulation, and protein localization in many eukaryotic organisms. However, its function remains largely unknown in plant species. In the present study, we analyzed a BTF3-related sequence in Oryza sativa L. ...
Patel Anisha N - - 2012
Major new insights on electrochemical processes at graphite electrodes are reported, through extensive investigations of two of the most studied redox couples, Fe(CN)64-/3- and Ru(NH3)63+/2+. Experiments have been carried out on 5 different grades of highly orientated pyrolytic graphite (HOPG) that vary in step edge height and surface coverage. Significantly, ...
Won Tae Hyung - - 2012
Nine new compounds, tris-aromatic furanones (1, 2, 3a, 3b, and 4) and related bis-aromatic diesters (5a, 5b, 6a, and 6b), are described from the ascidian Synoicum sp. collected off the coast of Chuja-do, Korea. The structures of these compounds, designated as cadiolides E and G-I (1-4) and synoilides A and ...
Bulitta Jürgen B - - 2013
The objectives of this analysis were to develop a population pharmacokinetic (PK) model to describe the absorption and disposition of fusidic acid after single and multiple doses and to determine the effect of food on the rate and extent of bioavailability. Plasma PK data from three phase 1 studies (n ...
Liu Su-Ling SL Institute of Molecular Biology and Department of Chemistry, University of Oregon, Eugene, Oregon 97403-1229, - - 2013
The Arp2/3 (actin-related protein 2/3) complex nucleates branched actin filaments involved in multiple cellular functions, including endocytosis and cellular motility. Two subunits (Arp2 and Arp3) in this seven-subunit assembly are closely related to actin and upon activation of the complex form a "cryptic dimer" that stably mimics an actin dimer ...
Sun Kai - - 2013
The effect of Cuscuta chinensis extract on the rabbit penile corpus cavernosum (PCC) was evaluated in the present study. Penises obtained from healthy male New Zealand white rabbits (2.5-3.0 kg) were precontracted with phenylephrine (Phe, 10 µmol l(-1)) and then treated with various concentrations of Cuscuta chinensis extract (1, 2, ...
Sun Li-Na - - 2012
The taxonomic status of a bacterium strain DC-8T, isolated from activated sludge, was determined using a polyphasic taxonomic approach. The cells of strain DC-8T were Gram-negative, non-motile, non-spore-forming and rod-shaped. The isolate grew at temperature range of 10-40°C (optimum 30-35 °C), pH range of 5.0-10.0 (optimum 6.5-8.0) and NaCl 0-5 ...
Albrecht Lukasz - - 2012
Giving directions: Optically active dihydropyrans bearing three contiguous stereogenic centers can be efficiently prepared by the title reaction. High stereo- and regiocontrol can be achieved by employing a bifunctional H-bond-directing aminocatalyst.
Cao Ning - - 2012
Background/Aims: The aim of this study was to investigate the effect of netrin-1 on peritubular capillary (PTC) loss and hypoxia in 5/6 nephrectomized (Nx) rats. Methods: Male Sprague-Dawley rats were divided into three groups (n = 10 rats/group): sham-operated rats treated with control adenovirus; 5/6 Nx rats treated with control ...
Dikicier Sibel - - 2012
Abstract AbstractObjective: Restoration of lost dentition in the severely atrophic posterior maxilla has been successfully treated with various sinus augmentation techniques such as using bone grafts and bone substitutes are frequently used to enable placement of dental implants. The aim of this study was to evaluate whether sinus membrane elevation ...
Lee Shoo K - - 2012
Objective To assess the association between altitudes of neonatal intensive care units (NICU) and the rate of bronchopulmonary dysplasia (BPD) and BPD/death in very preterm infants.Study Design Data from infants born at <33 weeks' gestation admitted to Canadian Neonatal Network during 2008 and 2009 were analyzed. The associations between the altitude of ...
Lepak Alexander J AJ University of Wisconsin, Madison, Wisconsin, - - 2013
Invasive pulmonary aspergillosis (IPA) is a devastating disease of immunocompromised patients. Pharmacodynamic (PD) examination of antifungal drug therapy in IPA is one strategy that may improve outcomes. The current study explored the PD target of posaconazole in an immunocompromised murine model of IPA against 10 A. fumigatus isolates, including 4 ...
Wykes Robert C RC UCL Institute of Neurology, London WC1N 3BG, - - 2012
Neocortical epilepsy is frequently drug-resistant. Surgery to remove the epileptogenic zone is only feasible in a minority of cases, leaving many patients without an effective treatment. We report the potential efficacy of gene therapy in focal neocortical epilepsy using a rodent model in which epilepsy is induced by tetanus toxin ...
Valero Rosendo - - 2012
The OH + CO → H + CO(2) reaction is important in combustion, atmospheric, and interstellar chemistry. Whereas the direct reaction has been extensively studied both experimentally and theoretically, the reverse reaction has received relatively less attention. Here we carry out a quasiclassical trajectory study of the hyperthermal H + ...
Pârvu Alina Elena AE Department of Pathophysiology, Faculty of Medicine, University of Medicine and Pharmacy "Iuliu Haţieganu," Cluj-Napoca, Romania. - - 2013
To evaluate the effectiveness of subantimicrobial-dose doxycycline (SDD) as an adjunct to scaling and root planing (SRP) treatment against the nitrosative stress of moderate to advanced chronic periodontitis. Adults with untreated chronic periodontitis (n=174) were randomly administered SRP+SDD (n=87) (20 mg of doxycycline twice daily) or SRP+placebo (n=87) treatment for ...
Mehta Akanksha - - 2013
Varicocelectomy is the most commonly performed surgical procedure for the treatment of male infertility. Although several different techniques for varicocele repair have been described in the literature, microsurgical varicocelectomy performed through a subinguinal or inguinal incision is recognized as the gold-standard approach for varicocelectomy, due to high success rates with ...
Van den Berg P J - - 2012
BACKGROUND: A new treatable venous disorder, chronic cerebrospinal venous insufficiency (CCSVI), has been proposed in patients with multiple sclerosis (MS). Its relationship with iron metabolism is suggested, but has not been examined prospectively. METHODS: We performed extra- and transcranial echo colour Doppler (ECD) in 90 patients with MS and 41 ...
Tamada Tsutomu - - 2012
PURPOSE: To compare the conspicuity of hypointense hepatocellular nodules in patients with chronic liver disease on hepatobiliary phase (HP) of gadolinium ethoxybenzyl diethylenetriamine pentaacetic acid (Gd-EOB-DTPA)-enhanced magnetic resonance imaging (MRI) acquired with low to high flip angles (FAs). MATERIALS AND METHODS: A total of 95 patients with chronic liver disease ...
Santos Tiago G - - 2012
Prion protein (PrP(C) ) is a cell surface glycoprotein that is abundantly expressed in nervous system. The elucidation of the PrP(C) interactome network and its significance on neural physiology is crucial to understanding neurodegenerative events associated with prion and Alzheimer's diseases. PrP(C) co-opts stress inducible protein 1/alpha7 nicotinic acetylcholine receptor ...
Uchida Masahiko - - 2012
The clinical course of chronic pancreatitis (CP) worsens with drinking, and pancreatic stellate cells (PSCs) have an important role in the pathogenesis of alcoholic CP. Chemokines recruit inflammatory cells, resulting in chronic pancreatic inflammation. Although serum levels of fractalkine (CX3CL1) are significantly elevated in patients with alcoholic CP, the mechanism ...
Uraguchi Daisuke - - 2012
A vinylog of Michael addition (1,6-addition) of azlactones to δ-substituted dienyl N-acylpyrroles has been developed with virtually complete 1,6-, diastereo-, and enantioselectivities by means of chiral P-spiro triaminoiminophosphorane as a catalyst. This system has been successfully extended to an unprecedented bis-vinylog of Michael addition (1,8-addition) of azlactones to ζ-substituted trienyl ...
Mate C Mathew - - 2012
The radii R of the area wetted by precursor films spreading from small droplets of polymer liquids are found to vary as R ~ t(ν) with ν = 0.32-0.42, in contradiction to the 0.5 exponent indicated in previous studies. The experiments reported here are for three of the same polymer ...
Yu Xiaobin - - 2012
Herba Epimedii, an herb commonly used in East Asian medicine, is commonly used for treatment of impotence, osteoporosis and many inflammatory conditions in traditional Chinese medicine. Recent studies revealed that Herba Epimedii also has anti-tumor or anti-cancer activities, which may possibly be mediated through anti-angiogenesis. This study aims to examine ...
Gould Virginia C - - 2013
A Stenotrophomonas maltophilia mutant that coordinately hyper-expresses three resistance nodulation division-type efflux pump genes, smeZ, smeJ, and smeK, has been identified. SmeZ is responsible for elevating aminoglycoside MICs; SmeJ and SmeK are jointly responsible for elevating tetracycline, minocycline, and ciprofloxacin MICs and conferring levofloxacin resistance. One clinical isolate with this ...
Atkins J A - - 2012
A single ovulation, reciprocal embryo transfer study was used to investigate effects of oocyte competence and maternal environment on pregnancy establishment and maintenance in beef cows. Estrous cycles were synchronized in suckled beef cows and embryo donors were inseminated on d 0 (n = 810). Cows were classified on d ...
Ernst Lena H - - 2012
An approach bias for alcohol stimuli (i.e. faster approach than avoidance reactions) might facilitate relapses in alcohol dependence. Neurobiological models suggest hypersensitivity in the reward system [inter alia nucleus accumbens and orbitofrontal cortex (OFC)] to cause pathologically enhanced approach impulses towards alcohol stimuli. At the same time, in alcohol dependence, ...
Cicchillitti Lucia L IRCCS-Policlinico San Donato, 20097 Milan, - - 2012
MicroRNA-210 (miR-210) induction is a virtually constant feature of the hypoxic response in both normal and transformed cells, regulating several key aspects of cardiovascular diseases and cancer. We found that miR-210 was induced in normoxic myoblasts upon myogenic differentiation both in vitro and in vivo. miR-210 transcription was activated in ...
Park Shin Hae - - 2012
Purpose: To determine the association of single nucleotide polymorphisms (SNPs) in the promoter region of the lumican (LUM) gene with high myopic Korean patients. Methods: Genomic DNA samples were obtained from 128 unrelated Korean patients with high myopia who had refractive errors ≤ -9.25 and axial lengths ≥ 26.5 mm in ...
Rath Detlef - - 2012
Pre-selection of spermatozoa based on the relative DNA difference between X- and Y- chromosome bearing populations by flow cytometry is an established method that has recently been introduced into commercial cattle production. Although several important improvements have increased the sort efficiency, the fertilizing ability of sexed spermatozoa based on offspring ...
Sales M O - - 2012
In this paper we study a one-dimensional ternary harmonic chain with the mass distribution constructed from an Ornstein-Uhlenbeck process. We generate a ternary mass disordered distribution by generating the correlated Ornstein-Uhlenbeck process and mapping it into a sequence of three different values. The probability of each value is controlled by ...
Wallys Jens - - 2012
We show that the photoluminescence intensity of GaN and InGaN nanowires in electrolytes sensitively responds to variations of the pH value and the applied bias. The realization of an electrochemical working point allows pH detection with a resolution better than 0.05 pH. The observed effects are attributed to bias-dependent nonradiative ...
Wolff Margaret - - 2012
BACKGROUND:Neonatal hyperbilirubinemia is a common reason for neonates to present to the emergency department (ED). Although clinical practice guidelines provide recommendations for evaluation and therapy, few studies have evaluated ways to apply them effectively in the ED setting. The primary objective of this study was to compare time to phototherapy ...
Sukumar Poornima - - 2012
A wide variety of microorganisms known to produce auxin and auxin precursors form beneficial relationships with plants and alter host root development. Moreover other signals produced by microorganisms affect auxin pathways in host plants. The precise role of auxin and auxin signaling pathways in modulating plant-microbe interactions, however, is unknown. ...
Fűlöpová Veronika - - 2012
Solid-phase synthesis of 3,4-dihydro-benzo[e][1,4]diazepin-5-ones with three diversity positions is described. Various primary amines were used as the starting material and immobilized on the polystyrene resin equipped with different acid-labile linkers. Polymer supported amines were converted to -aminoketones with the use of their sulfonylation with the p-nitrobenzensulfonylchoride and subsequent alkylation with ...
Chevrier Inès - - 2012
Complexes with silver ions have great potential for applications in medicine. Appropriate bidentate ligands, binding to silver ions, are able to generate coordination polymers as well as molecular entities as a function of ligand flexibility, conformation and length. Here we present the continuation of our previous studies in this field ...
Chen Shanliang - - 2012
This study comparatively evaluates the characteristics of glutaraldehyde-treated acellular bovine and donkey pericardium using histological and electronic microscopic observation techniques, shrinkage temperature, and mechanical properties, as well as determining calcium and phosphorus content at 4 and 8 weeks after the subcutaneous implantation of donkey and bovine pericardium in Wistar rats. ...
Grijsen Marlous L - - 2012
A high prevalence of low bone mineral density (BMD) has been reported in primary and chronic HIV-infected men. To gain further insight into the contribution of HIV-infection, we compared the BMD of 41 primary and 106 chronic HIV-infected men who have sex with men (MSM) with the BMD of a ...
Pandolfi S - - 2012
The Hedgehog-GLI (HH-GLI) signaling plays a critical role in controlling growth and tissue patterning during embryogenesis and is implicated in a variety of human malignancies, including those of the skin. Phosphorylation events have been shown to regulate the activity of the GLI transcription factors, the final effectors of the HH-GLI ...
Krishna Murali - - 2012
OBJECTIVES: Studies investigating the effectiveness of group psychotherapy intervention in sub-threshold depression have shown varying results with differing effect sizes. A systematic review of randomised controlled trials of group psychotherapy in older adults with sub-threshold depression was conducted to present the best available evidence in relation to its effect on ...
Vervliet B - - 2012
The modeling of abnormal behavior in 'normal' subjects (often animals) has a long history in pharmacological research for the screening of novel drug compounds. Systematic criteria have been outlined in that literature to estimate the external validity of a model, that is to estimate how closely the model is linked ...
Chisholm Malcolm H - - 2012
While chemists have extensively studied the photophysical properties of d(6), d(8), and d(10) transition metal complexes, their early transition metal counterparts have received less attention. Quadruply bonded complexes of molybdenum and tungsten supported by carboxylate ligands have intense metal-to-ligand charge transfer (MLCT) absorptions that arise from the electronic coupling of ...
Alkan-Bozkaya Tijen - - 2013
The aim of this clinical trial was to evaluate the pulsatile perfusion mode in pediatric patients who had complex cardiac pathologies according to Jenkins stratifications (category 4) undergoing cardiopulmonary bypass procedures (CPB). Patients with transposition of great arteries (TGA) and ventricular septal defect (VSD) were included in this clinical study. ...
Vilacoba Elisabet - - 2013
Resistance to minocycline has emerged in multidrug-resistant Acinetobacter baumannii isolates from Buenos Aires hospitals. Few reports about the description and dispersion of tet genes in this species have been published. We observed the presence of tet(B) in all minocycline-resistant isolates. This gene was found to be associated with the ISCR2 ...
Lu Su - - 2012
The present research validated the construct and criterion validities of the Cooperative and Competitive Personality Scale (CCPS) in a social dilemma context. The results from three studies supported the notion that cooperativeness and competitiveness are two independent dimensions, challenging the traditional view that they are two ends of a single ...
Kanavarioti Anastassia A Halcyon Molecular, Inc., Redwood City, CA, USA. - - 2012
With the recent advances in electron microscopy (EM), computation, and nanofabrication, the original idea of reading DNA sequence directly from an image can now be tested. One approach is to develop heavy atom labels that can provide the contrast required for EM imaging. While evaluating tentative labels for the respective ...
Beukers Fenny - - 2012
BACKGROUND: In preterm hypertensive disorders of pregnancy, fetal growth restriction (FGR) occurs frequently. The timing and severity of FGR impacts childhood growth and is associated with metabolic changes later in life. AIM: To examine growth and the impact of FGR in early childhood. DESIGN: Prospective cohort study. PARTICIPANTS: Children (n=135) ...
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