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Lavelle Bridget - - 2012
This article bridges the literatures on the economic consequences of divorce for women with that on marital transitions and health by focusing on women's health insurance. Using a monthly calendar of marital status and health insurance coverage from 1,442 women in the Survey of Income and Program Participation, we examine ...
Coronado Eugenio - - 2012
In this review we combine the use of coordination chemistry with the concepts of molecular magnetism to design magnetic Metal-Organic Frameworks (MOFs) in which the crystalline network undergoes a dynamic change upon application of an external stimulus. The various approaches so far developed to prepare these kinds of chemically or ...
Siciliano Carlo - - 2012
The study describes a new "one-pot" route to the synthesis of N-9-fluorenylmethyloxycarbonyl (Fmoc) α-amino diazoketones. The procedure was tested on a series of commercially available free or side-chain protected α-amino acids employed as precursors. The conversion into the title compounds was achieved by masking and activating the α-amino acids with ...
Fox C W - - 2012
Little is known about how inbreeding alters selection on ecologically relevant traits. Inbreeding could affect selection by changing the distribution of traits and/or fitness, or by changing the causal effect of traits on fitness. Here, I test whether selection on egg size varies with the degree of inbreeding in the ...
Nagahara Noriyuki - - 2012
Significance: Redox regulates 3-mercaptopyruvate sulfurtransferase (MST, EC 2.8.1.2) activity via both intermolecular and intramolecular redox-sensing switches. The intermolecular switch comprises an intermolecular disulfide bond that forms a homodimer. On the other hand, the intramolecular switch is a catalytic site cysteine that forms a low redox potential sulfenate. Both switches are ...
Pratlong Francine - - 2012
SUMMARY A series of 2277 Leishmania strains from Old World visceral leishmaniasis foci, isolated between 1973 and 2008, were studied by isoenzyme analysis. The strains were obtained from humans, domestic and wild carnivores, rodents and phlebotomine sandflies, and came from 36 countries. In all, 60 different zymodemes were identified and ...
Stam Anine H - - 2012
AimMigraine, in particular with aura, has been associated with an increased risk for ischemic stroke and coronary heart disease. The underlying mechanism is unknown. In a cross-sectional case control study we investigated whether an enhanced risk of atherosclerosis in migraineurs explains this increased cardiovascular risk.MethodsSubjects were participants from the population-based ...
Lambrinoudaki I - - 2012
Objective To assess the interaction of the MTHFR C677T polymorphism with changes in lipid and glucose metabolism effected by oral hormone replacement therapy (HRT) in postmenopausal women. Methods In this open-label, prospective, interventional study, parameters of lipid and glucose metabolism, as well as homocysteine, were assessed in 97 postmenopausal women ...
Giles Logan J - - 2012
In this work, we demonstrate the potential of multi-edge X-ray absorption near-edge structure (XANES) analysis in completely defining the ground state electronic structure of a prototypical biomimetic complex of the [2Fe]-subcluster of the catalytic H-cluster of FeFe-hydrogenase. The spectral features at the ionization thresholds for Fe, S, C and O ...
Lord Gillian - - 2012
Total arsenic and four arsenic species; arsenite (iAs(III)), arsenate (iAs(V)), dimethylarsinic acid (DMA(V)) and monomethylarsonic acid (MA(V)), are reported in 28 geothermal features from the Taupo Volcanic Zone (TVZ) and Waikato region of New Zealand. Samples were collected for arsenic speciation analysis via a solid phase extraction (SPE) kit allowing ...
Villeneuve Céline - - 2012
Two bacterial strains, designated JAM1T and JAM7T, were isolated from a methanol-fed denitrification system treating seawater at the Montreal Biodome, Canada. They were affiliated within the Methylophaga genus of the Gammaproteobacteria by analysis of the 16S ribosomal RNA gene sequences. Strain JAM1T has the capacity to grow under denitrifying conditions ...
Eyet Nicole - - 2012
The gas-phase reactions of F(-)(DMSO), F(-)(CH(3)CN), and F(-)(C(6)H(6)) with t-butyl halides were investigated. Reaction rate constants, kinetic isotope effects, and product ion branching ratios were measured using the flowing afterglow selected ion flow tube technique (FA-SIFT). Additionally, the structure of F(-)(DMSO) was investigated both computationally and experimentally, and two stable ...
Kamakura Naoto - - 2012
Hydroxyl radicals generate a broad range of DNA lesions in living cells. Cyclopurine deoxynucleosides (cPu) are a biologically significant class of oxidative DNA lesions due to their helical distortion and chemically stability. The cPu on DNA are substrates for the nucleotide excision repair (NER), but not for base excision repair ...
Batisai Eustina - - 2012
Mechanochemical synthesis has been used to obtain two Werner complexes and their solid solution that could not be obtained by conventional "wet" chemistry; remarkably, despite the structural and chemical similarity, the solid solution exhibits sorption properties that differ from those of the pure compounds.
Haberberger Michael - - 2012
An iron-catalyzed hydroboration of alkynes to produce vinylboronates has been examined. With a straightforward system composed of iron carbonyls and pinacolborane, good to excellent yields and chemoselectivities were achieved for a variety of alkynes.
Wang Lei - - 2012
Despite the reports of the occurrence of bisphenol A diglycidyl ether (BADGE) and its derivatives in canned foods and consumer products, biomonitoring studies of human exposure to these compounds are lacking. In this study, 127 urine samples collected from the U.S. and China were analyzed for free and total (free ...
Hagenbuchner J - - 2012
Gain of chromosome 17q correlates with high-stage disease, an adverse clinical outcome and leads to the overexpression of the antiapoptotic protein BIRC5/Survivin in neuroblastoma (NB). We have shown before that Survivin defines a threshold for the sensitivity of NB cells to DNA-damaging chemotherapeutic agents that require FOXO3 activation for apoptosis ...
Parri Matteo - - 2012
SIGNIFICANCE. We herein review recent advances on the role exerted by protein redox machines engaged in tumor progression, focusing on cell adhesion and migration, regulation of transcriptional response and tumor metabolic reprogramming, all features belonging to the new hallmarks of cancer. RECENT ADVANCES. Several recent insights have reported that oxidative ...
Edge J A - - 2012
AIM: Hospital inpatient care for children with diabetes is frequently mentioned by parents as unsatisfactory. The aim of this study was to examine the reasons for inpatient admission of children with diabetes and to understand patient and carer experience in order to improve services. METHODS: Questionnaires were given to medical ...
Haberhauer Gebhard - - 2012
Significance: This review relates to artificial redox-driven molecular devices. The advantages of using very simple chemical building blocks for the bottom-up design of nano-leveled functional motors and the importance of the unidirectionality of a switching process for the development of redox-driven molecular motors are discussed. Furthermore, the crucial difference between ...
Yoon Hyun Kyung - - 2012
Objective. Aberrant splicing is one of the most significant components generating functional diversity in many pathological conditions. The objective of this study was to analyse the mutations or aberrant splicing of A20 transcript, the region encompassing the ovarian tumour (OTU) domain [which is functionally important as an inhibitor of nuclear ...
Yasuda Norihisa - - 2012
In this report, we studied whether plasma concentration of nicorandil is maintained effectively and safely in dialysis-dependent patients with stage 5 chronic kidney disease (CKD5D) undergoing continuous renal replacement therapy (CRRT). Participants consisted of 10 patients undergoing CRRT after cardiac surgery. CRRT was performed with an effluent flow rate of ...
Usher K - - 2012
ACCESSIBLE SUMMARY: Weight gain is a known, predictable side-effect of second-generation antipsychotic drugs. Study participants reported struggling to manage the insatiable appetite and weight gained associated with the drugs. Cessation of prescribed medication was considered by most as a way of managing the weight gain associated with the drugs. ABSTRACT: ...
Golden Neville H - - 2012
OBJECTIVE:To test the hypothesis that the weight-for-stature (WFS) and BMI methods are not equivalent in determining expected body weight (EBW) in adolescents with eating disorders and to determine the sensitivity, specificity, and positive predictive value of each method to detect those <75% EBW. We hypothesized that differences in EBW would ...
Lomoth Reiner - - 2012
Significance: Control over reversible changes to molecular structure forms the basis for artificial molecular machines that could eventually lead to the development of molecule based nanotechnology. Recent Advances: Particular applications in information storage and processing could emerge where the structural rearrangements give rise to bistability and molecular hysteresis effects. Critical ...
He Xi - - 2012
Ischemic preconditioning (IPC) strongly protects against ischemia/reperfusion (I/R) injury; however, the molecular mechanism involved in delayed preconditioning-induced endothelial protection in peripheral arteries is unknown. Therefore, we examined using functional, morphologic and molecular biologic studies whether delayed IPC decreases formation of reactive oxygen species and upregulates endothelial nitric oxide synthase (eNOS) ...
Gheidi Mahin - - 2012
Iron-oxophlorin is an intermediate in heme degradation, and the metal oxidation number can alter spin, electron distribution, and the reactivity of the metal and the oxophlorin ring. The role of electron transfer in the structure and reactivity of [(Py)(2)Fe(III)(PO)] (PO is the oxophlorin trianion) in different redox states has been ...
Mooney Thomas J - - 2012
Several fuel spills have occurred on subantarctic Macquarie Island (54°30' S 158°57' E) associated with storing fuel and generating power for the Island's research station. The Australian Antarctic Division began full-scale, on-site remediation of these sites in 2009. To develop appropriate target concentrations for remediation, acute and chronic tests were ...
Gourbeyre Pascal - - 2012
Prebiotics constitute emerging tools to alleviate immune pathologies. This study aimed to evaluate the effect of prebiotic exposure during perinatal and post-weaning periods on immune and gut regulations. Mice were fed either a galactooligosaccharides/inulin prebiotic mix-enriched diet or a control diet during the perinatal and/or post-weaning periods. Biomarkers related to ...
Mc Donnell Conor - - 2012
INTRODUCTION: Clinical outcomes in pediatric anesthesia have improved significantly over the last 20-30 years but unexpected laryngospasm that is difficult to treat can still result in patient morbidity, increased postoperative medical management and unnecessary hospital admission. The incidence of laryngospasm in pediatric anesthesia is difficult to determine with incidences from 0.9% ...
Blake John T - - 2012
BACKGROUND: Since the 1970s red blood cells (RBCs) have had a rated shelf life of 42 days. Recently, studies have suggested poorer patient outcomes when older blood is transfused. However, shortening the shelf life of RBCs may increase costs and lead to greater instances of outdates and shortages. STUDY DESIGN ...
Armfield Nigel R - - 2012
Telemedicine was used as a substitute for the telephone (usual care) for some acute care consultations from nurseries at four peripheral hospitals in Queensland. Over a 12-month study period, there were 19 cases of neonatal teleconsultation. Five (26%) cases of avoided infant transport were confirmed by independent assessment, four of ...
Bennett G L - - 2012
Genetic markers in casein (CSN1S1) and thyroglobulin (TG) genes have previously been associated with fat distribution in cattle. Determining the nature of these genetic associations (additive, recessive or dominant) has been difficult because both markers have small minor allele frequencies in most beef cattle populations. This results in few animals ...
Canevelli Marco - - 2012
OBJECTIVE: Behavioral and psychological symptoms of dementia represent common clinical features of dementias, contributing to the heterogeneous phenotypic expression of Alzheimer's disease (AD). During the last two decades, several studies explored the possible presence of neuropsychiatric subsyndromes in dementia by examining the internal structure of the Neuropsychiatric Inventory (NPI). The ...
Arnell Katharine - - 2012
Esophageal neoplasia is an uncommon, but important, consideration for acute and chronic regurgitation and megaesophagus in dogs. The diagnosis can be challenging, and treatment options are often limited. This case series describes four dogs with regurgitation secondary to caudal esophageal masses. All dogs presented with regurgitation, and three of the ...
Qin Sheng - - 2012
A novel actinomycete, designated strain KLBMP 1279T, was isolated from surface-sterilized roots of a coastal halophyte Salicornia europaea Linn. collected from Jiangsu Province, east of China. The taxonomic status of this organism was established using a polyphasic approach. 16S rRNA gene sequence analysis indicated that strain KLBMP 1279T was closely ...
Eastwood Emily C - - 2012
There has been little investigation of genetic factors and associated mechanisms that influence risk for development of methamphetamine (MA) dependence. Selectively bred mouse lines that exhibit high (MAHDR) or low (MALDR) levels of MA intake in a two-bottle choice MA drinking (MADR) procedure provide a genetic tool for this purpose. ...
Sun Hui - - 2012
Zhi Zhu Wan (ZZW), a classical Chinese medical formulae consisted of Atractylodes Rhizome and Fructus Citrus Immaturus, has been commonly used for treatment of gastrointestinal diseases. Hesperetin and naringenin are the main components of ZZW, and both can alleviate intestinal tract disorders. In this work, plasma pharmacokinetics and pharmacodynamics characteristics ...
Liebl Florian - - 2012
PURPOSE: Neural invasion/NI is a histopathological feature of colon cancer/CC which receives little consideration. Therefore, we performed a morphological and functional characterization of NI in CC. EXPERIMENTAL DESIGN: NI was investigated in 673 patients with CC. Localization and severity of NI was determined and related to patient's prognosis and survival. ...
Kim Jihoon - - 2012
The growing interest in membrane interactions of amyloidogenic proteins indicates that lipid binding and the regulation of membrane potential are critical to the onset and progression of neurodegenerative diseases such as Parkinson's (PD), Alzheimer's (AD) and prion diseases. Advancing the understanding of this field requires the application of varied biophysical ...
Yamada Ken-Ichi - - 2012
A highly efficient short-step construction of the common phenanthridine skeleton of pancratistatin-class alkaloids was accomplished in enantiomerically pure form using chiral ligand-controlled asymmetric conjugate addition. The utility of the intermediate was demonstrated by the total synthesis of (+)-trans-dihydronarciclasine with mild oxidation from an amine to an amide as a key ...
Zhou Wu - - 2012
We show that aberration-corrected scanning transmission electron microscopy operating at low accelerating voltages is able to analyze, simultaneously and with single atom resolution and sensitivity, the local atomic configuration, chemical identities, and optical response at point defect sites in monolayer graphene. Sequential fast-scan annular dark-field (ADF) imaging provides direct visualization ...
Li Hong - - 2012
A [1]rotaxane, in which a linear rod is attached to one cyclopentadienyl (Cp) ring of a ferrocene unit and threaded into a dibenzo-24-crown-8 connected to the other Cp ring, was prepared. The mechanical motion of the rod-like part relative to the macrocycle has been demonstrated using (1)H NMR spectroscopy. Cyclic ...
Fujimoto Koichi - - 2012
SM-295291 and SM-369926 are new parenteral 2-aryl carbapenems with strong activity against major causative pathogens of community-acquired infections such as methicillin-susceptible Staphylococcus aureus, Streptococcus pneumoniae including penicillin-resistant strains, Streptococcus pyogenes, Enterococcus faecalis, Klebsiella pneumoniae, Moraxella catarrhalis, Haemophilus influenzae including β-lactamase negative ampicillin-resistant strains, and Neisseria gonorrhoeae including ciprofloxacin -resistant strains, ...
Xie Ruilong - - 2012
A simple and efficient copper-catalyzed method for the synthesis of 11H-benzo[a]carbazoles has been developed. The protocol uses readily available substituted 2-(2-bromophenyl)-1H-indoles and ketones as starting materials and an inexpensive catalyst system. The corresponding 11H-benzo[a]carbazoles were obtained in moderate to excellent yields.
Farias Luis Henrique S - - 2012
Background. Phosphatidylserine (PS) and surface carbohydrates (SC) are known as virulence factors that may contribute to the different clinical symptoms from self-healing cutaneous leishmaniasis lesions up to fatal visceral disease. Leishmania braziliensis causes localized cutaneous (LCL) and muco-cutaneous leishmaniasis (MCL).Methods. We analyzed PS exposure and SC expression of two primary Leishmania braziliensis ...
Kim B G - - 2012
An experiment was conducted to determine the true ileal digestibility (TID) and the true total tract digestibility (TTTD) of acid-hydrolyzed ether extract (AEE) in extracted corn oil, high-oil corn, distillers dried grains with solubles (DDGS), corn germ, and high protein distillers dried grains (HP DDG), and to compare these values ...
Strelcov Evgheni - - 2012
A new high-yield method of doping VO2 nanostructures with aluminum is proposed, which renders possible stabilization of the monoclinic M2 phase in free-standing nanoplatelets in ambient conditions and opens an opportunity for realization of a purely electronic Mott Transition Field-Effect Transistor without an accompanying structural transition. The synthesized free-standing M2-phase ...
Starmans Maud Hw - - 2012
ABSTRACT: BACKGROUND: The advent of personalized medicine requires robust, reproducible biomarkers that indicate which treatment will maximize therapeutic benefit while minimizing side-effects and costs. Numerous molecular signatures have been developed over the last decade to fill this need, but their validation and up-take into clinical settings has been poor. Here, ...
Van De Logt Floor - - 2012
The inflammatory bowel diseases are incurable conditions that feature gut inflammation. Standard markers have inadequate sensitivity and specificity. S100A12 is a new faecal marker than has promise as a non-invasive indicator of gut inflammation. This article reviews recent studies focusing on S100A12 and highlights current and potential roles of this ...
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