Search Results
Results 201 - 250 of 4626
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Sinha Sujeet Kumar - - 2012
The vestibulocochlear nerve is a sensory nerve that serves the organs of hearing and equilibrium. Neuropathies of the nerve, particularly auditory neuropathy may be caused by primary demyelination or by axonal diseases. In disorders affecting the cochlear nerve, it is probable that the vestibular nerve is involved as well. There ...
Moro Maria Luisa - - 2012
Aβ is the main component of amyloid deposits in Alzheimer disease (AD) and its aggregation into oligomers, protofibrils and fibrils is considered a seminal event in the pathogenesis of AD. Aβ with C-terminus at residue 42 is the most abundant species in parenchymal deposits, whereas Aβ with C-terminus at residue ...
Porena Massimo - - 2012
PURPOSE: To evaluate the long-term functional results and complications of an orthotopic ileal neobladder, defined as perugia ileal neobladder (PIN), in a group of patients with bladder cancer who underwent radical cystectomy (RC). METHODS: Between 1993 and 2009, 237 consecutive patients who underwent RC for non-metastatic bladder cancer and orthotopic ...
Maniu Alma - - 2012
The aim of this study was to assess the hearing results after unilateral stapes surgery for otosclerosis at Cluj-Napoca University Hospital, and to evaluate surgical trauma to the inner ear in these patients. The medical records of 387 consecutive patients who underwent unilateral stapes surgery were reviewed. Hearing results were ...
Momin M A - - 2012
PURPOSE: To determine the width and morphology of the mandible in the impacted third molar region, and to identify the location of the mandibular canal prior to planning impacted third molar operations. METHODS: Cone beam computed tomography (CBCT) data of 87 mandibular third molars from 62 Japanese patients were analyzed ...
Zhou Youlang - - 2012
Gekko japonicus undergoes dramatic changes in the caudal spinal cord after tail amputation. The amputation induces cell proliferation in the caudal ependymal tube. We performed hematoxylin and eosin staining at different time points in the regeneration process to investigate the morphological characterization of the regenerated appendages. The central canal extended ...
Biedermann Thomas - - 2012
PURPOSE: Tissue engineered skin substitutes are a promising tool to cover large skin defects, but little is known about reinnervation of transplants. In this experimental study, we analyzed the ingrowth of host peripheral nerve fibers into human tissue engineered dermo-epidermal skin substitutes in a rat model. Using varying cell types ...
Thomas James P - - 2012
The objectives of this study were: (1) to determine the percentage of patients seen in a private laryngology clinic with voice-related disorders previously diagnosed with and treated for laryngopharyngeal reflux (LPR); (2) to determine how many of those patients are found to have disorders other than LPR as a cause ...
Brockington Alice - - 2012
A consistent clinical feature of amyotrophic lateral sclerosis (ALS) is the sparing of eye movements and the function of external sphincters, with corresponding preservation of motor neurons in the brainstem oculomotor nuclei, and of Onuf's nucleus in the sacral spinal cord. Studying the differences in properties of neurons that are ...
Zaldivar Andrew - - 2012
Neuromodulatory systems originate in nuclei localized in the subcortical region of the brain and control fundamental behaviors by interacting with many areas of the central nervous system. An exploratory survey of the cholinergic, dopaminergic, noradrenergic, and serotonergic receptor expression energy in the amygdala, and in the neuromodulatory areas themselves was ...
Boillat Sébastien - - 2012
This paper aims to deepen the search for ecosystem-like concepts in indigenous societies by highlighting the importance of place names used by Quechua indigenous farmers from the central Bolivian Andes. Villagers from two communities in the Tunari Mountain Range were asked to list, describe, map and categorize the places they ...
Bes Cemal C Department of Rheumatology, Bakirköy Dr. Sadi Konuk Education and Research Hospital, Istanbul, Turkey. - - 2013
Anemia is one of the extra-articular findings of ankylosing spondylitis (AS), and anti-TNF therapy has been shown benefit in patients with anemia associated AS. In this study, we aimed to evaluate and compare the effects of biological and non-biological agents on hemoglobin levels in AS patients. One hundred consecutive patients ...
Fitzpatrick Sarah G SG Department of Oral Pathology, Case Western Reserve University School of Dental Medicine, Cleveland, OH, - - 2013
CD44 is a transmembrane adhesion molecule which has been previously shown to be useful in the differentiation of benign papillary lesions from invasive carcinoma in several different areas including sinonasal mucosa and breast tissue. CD44 expression has previously been shown to be lost in invasive carcinoma and retained in benign ...
Li Bing - - 2012
PURPOSE: Jejunal-ileal atresias are the most common causes of intestinal occlusion in neonatal period. Treatment is classically performed by a right upper quadrant transverse laparotomy. Our study aimed to present our initial experience of intestinal atresia in newborn treated with laparoscopic assisted approach. METHODS: Overall 35 small intestinal atresias, which ...
Garriboli Massimo - - 2012
PURPOSE: Morgagni diaphragmatic hernia can be repaired laparoscopically. The aim of this study is to evaluate the outcome of this minimally invasive approach. METHODS: A retrospective review was conducted on all consecutive children who underwent repair of Morgagni hernia from January 2002 to December 2011 in our hospital. Data are ...
Zhang Mingxi - - 2012
A dispersion-dominated colorimetric approach for the recognition of carbohydrates based on biomolecule-responsive AuNPs is presented. Taking advantage of the unique dual-responsiveness of smart copolymers, the aggregation and dispersion of AuNPs can be modulated by both temperature and different kinds of carbohydrates, giving rise to a novel chromogenic mechanism for the ...
Çuburu Nicolas - - 2012
The induction of persistent intraepithelial CD8+ T cell responses may be key to the development of vaccines against mucosally transmitted pathogens, particularly for sexually transmitted diseases. Here we investigated CD8+ T cell responses in the female mouse cervicovaginal mucosa after intravaginal immunization with human papillomavirus vectors (HPV pseudoviruses) that transiently ...
Beard George F - - 2012
Roll compensation during cornering (aligning the feet-to-head axis of the body with the resultant force) reduces lateral acceleration, but how any improvement in comfort depends on the frequency of the acceleration has not previously been investigated. Seated subjects judged the discomfort caused by lateral oscillation, roll oscillation and fully roll-compensated ...
Chauhan Nidhi N Department of Biochemistry, M. D. University, Rohtak, Haryana, - - 2013
Human swine influenza A [H1N1], also referred to as "swine flu," is highly transmissible. The emergence of new strains will continue to pose challenges to public health and the scientific communities will have to prepare to detect them for appropriate treatment. Most sophisticated methods include immunofluorescence staining and antigen subtyping ...
Jones R Brad RB Department of Immunology, University of Toronto, and Li Ka Shing Knowledge Institute, St. Michael’s Hospital, Toronto, Ontario, Canada. - - 2012
The genetic diversity of HIV-1 represents a major challenge in vaccine development. In this study, we establish a rationale for eliminating HIV-1-infected cells by targeting cellular immune responses against stable human endogenous retroviral (HERV) antigens. HERV DNA sequences in the human genome represent the remnants of ancient infectious retroviruses. We ...
Byrne Abbey - - 2012
ABSTRACT: BACKGROUND: Unmet need for family planning is responsible for 7.4 million disability-adjusted life years and 30% of the maternity-related disease burden. An estimated 35% of births are unintended and some 200 million couples state a desire to delay pregnancy or cease fertility but are not using contraception. Unmet need ...
Zha Zhengbao - - 2012
Uniform polypyrrole (PPy) nanoparticles were fabricated from a facile one-step aqueous dispersion polymerization. Owing to their high photothermal conversion efficiency and photostability compared with the well-known Au nanorods, as well as their good colloidal stability and biocompatibility, the resulting PPy nanoparticles could be used as a novel promising photothermal ablation ...
Tong Yuye J - - 2012
Promoters and poisons for catalytic activity have been a subject of intensive research in both heterogeneous catalysis and electrocatalysis for decades, driven primarily by profound financial and societal implications involved because catalyzed reactions are at the center of many enterprises of chemical and petroleum industries. Consequently, there exist well-identified promoters ...
Zhang S - - 2012
Background: Platelet ADP receptor P2Y(12) is well studied and recognized as a key player in platelet activation, haemostasis and thrombosis. However, the role of P2Y(12) in platelet apoptosis remains unknown. Objectives: To evaluate the role of P2Y(12) receptor in platelet apoptosis. Methods: We used flow cytometry and western blotting to assess apoptotic events ...
Lenning Emily - - 2012
Using narrative analysis, this study uses survey data to explore the social, psychological and economic challenges faced by transgender individuals and their significant others. With over 300 participants, this study not only validates the findings of previous yet smaller scale studies surrounding the transgender experience, it adds greater context to ...
Carrasco Esther - - 2012
The properties of the interfacial water monolayer on MgO(001) during growth of multilayer ice and, in particular, the dewetting of crystalline ice on MgO(001) are revealed by vibrational sum frequency generation and infrared reflection absorption spectroscopy.
Kurtikyan Tigran S - - 2012
Reaction of NO with amorphous Mn(TPP) layers gives two Mn(TPP)(NO) isomers with linear and bent Mn-N-O geometries that reversibly interconvert with changes in temperature. DFT computations predict that the linear complex is the singlet ground state while the bent structure is a triplet state.
Strohmeier Oliver - - 2012
Transportation of magnetic beads between different reagents plays a crucial role in many biological assays e.g. for purification of biomolecules or cells where the beads act as a mobile solid support. Therefore, usually a complex set-up either for fluidic processing or for manipulation of magnetic beads is required. To circumvent ...
Li Shenghai - - 2012
A novel SPES-NH(2)-GA-Nafion® composite membrane with higher proton conductivity and lower methanol permeability was fabricated by covalent crosslinking layer-by-layer self-assembly of an unbalanced charged polyampholyte (SPES-NH(2)) and glutaraldehyde (GA) with controllable free sulfonic acid content.
Gyi Diane - - 2012
The participatory process within four case study organisations with a target population of high mileage business drivers is described. The aim was to work with drivers and their managers to co-develop intervention activities to raise awareness of musculoskeletal health in drivers, including use of the car as a mobile office ...
Yu Xiao - - 2012
The unique anisotropic wet-etching mechanism of a (111) silicon wafer facilitates the highly controllable top-down fabrication of silicon nanowires (SiNWs) with conventional microfabrication technology. The fabrication process is compatible with the surface manufacturing technique, which is employed to build a nanowire-based field-effect transistor structure on the fabricated SiNW.
Préau Marie - - 2012
This study aimed to analyze the relationship between spirituality, coping strategies and health-related quality of life (HRQL) among a large representative sample of patients two years after cancer diagnosis. Using a cross-sectional design, medical and self-reported data were collected by physicians and a patient telephone interview, respectively. Among 4270 participants, ...
Hatiboglu Gencay - - 2012
Abstract Objective. The aim of this study was to evaluate the prognostic relevance of melanoma-associated antigen (MAGE) A9 in renal cell carcinoma (RCC). Material and methods. Immunohistochemical staining for MAGE A9 was evaluated in a tissue microarray containing 587 RCC tumour tissue samples. Nuclear MAGE A9 expression was reviewed using ...
Curnis Flavio - - 2012
A new cyclic peptide containing the isoDGR motif that, after coupling to albumin, selectively binds αvβ3, an integrin overexpressed in the tumor vasculature. IsoDGR-tagged albumin binds tumor vessels and can be exploited as a carrier for the preparation of tumor vasculature-selective nanomedicines, such as gold nanoparticles (Au) carrying tumor necrosis ...
Zhang Cai-Xia - - 2012
Few epidemiological studies have evaluated the association of choline and betaine intake with breast cancer risk and the results remain inconsistent. This study aimed to assess the relationship between dietary intake of choline and betaine and the risk of breast cancer among Chinese women. A two-stage case-control study was conducted, ...
Tsou Yung-An - - 2012
Overexpression of epidermal growth factor receptor (EGFR), Her2, and uroporphyrinogen decarboxylase (UROD) occurs in a variety of malignant tumor tissues. UROD has potential to modulate tumor response of radiotherapy for head and neck cancer, and EGFR and Her2 are common drug targets for the treatment of head and neck cancer. ...
Antti Alakärppä - - 2012
BACKGROUND: The Cochrane database of systematic reviews is an evidence-based medicine (EBM) database that provides the highest quality evidence of the effect of various treatments. Quality of life (QoL) is an important aspect when treatment effect is considered. OBJECTIVE: To assess how often patient-reported outcome measures (PROM), and specifically the ...
Yang Seung Yun - - 2012
Diamond-anvil cell, pressure-tuning infrared (IR), and Raman microspectroscopic measurements have been undertaken to examine the effects of high pressures up to about 45 kbar on the vibrational spectra of the four DNA bases, adenine, cytosine, guanine, and thymine. Small structural changes were evident for all the four bases, viz., for adenine ...
King Trevor K - - 2012
A pilot study examined the effectiveness of a biofeedback mouse in reducing upper extremity pain and discomfort in office workers; in addition, relative mouse use (RMU), satisfaction and the feasibility of running a randomised controlled trial (RCT) in a workplace setting were evaluated. The mouse would gently vibrate if the ...
Godier A - - 2012
Plasminogen is the proenzyme of plasmin, the key protease of the fibrinolytic system, but its role is not limited to fibrinolysis regulation. Plasminogen binds not only to fibrin, but also to different receptors on cell surfaces, including the heterotetrameric complex Annexin A2 - S100A10, enolase-1, histone H2B and the plasminogen ...
Lombardi Gaetano - - 2012
The clinical conditions associated with GH excess and GH deficiency are known to be associated with an increased risk for cardiovascular morbidity and mortality, suggesting that either an excess or a deficiency in GH and/or IGF-I is deleterious for cardiovascular system. In patients with acromegaly chronic GH and IGF-I excess ...
de Lima Assis Apio Cláudio - - 2012
This study employed functional and electrophysiological approaches to investigate the mechanisms by which warifteine, a bisbenzylisoquinoline alkaloid isolated from Cissampelos sympodialis Eichl, causes vasorelaxation in the rat thoracic aorta. Warifteine (1 pM-10 μM) induced a concentration-dependent relaxation (pD(2) =9.40±0.06, n=5) in endothelium-intact aortic rings pre-contracted with noradrenaline (10 - 100 ...
Piquemal Jean-Yves - - 2012
Based on selected examples from the literature, this perspective aims to provide a short overview of synthetic methods using hydrogen peroxide and/or peroxidic species for the elaboration of discrete or zero-dimensional species, as well as mono-, bi- and tri-dimensional materials. There are several advantages in using peroxidic species: no foreign ...
Visser Steven - - 2012
Screed floors are bound by sand-cement (SF) or by anhydrite (AF). Sand-cement floors are levelled manually and anhydrite floors are self-levelling and therefore differences in work demands and prevalences of musculoskeletal complaints might occur. The objective was to assess among SF layers and AF layers (1) the prevalence of musculoskeletal ...
Nick Costain - - 2012
KEY POINTS: Cochlear implant device fixation is an important aspect of the surgical procedure to ensure successful long-term outcomes. Inadequate device fixation may lead to constant shear stress, electrode fatigue and device extrusion or migration. Traditional fixation techniques involve bone-anchoring by drilling channels in the skull, which may lead to ...
Deng Hua - - 2012
Unmodified gold nanoparticles (GNPs) can be wrapped with long genomic single- and double-stranded DNA (ssDNA and dsDNA) molecules produced by asymmetric polymerase chain reaction (As-PCR). More importantly, the DNA-Au interaction can be utilized for colorimetric detection of a specific nucleic acid sequence in clinical samples.
Nishio Miki - - 2012
Mps one binder 1a (MOB1A) and MOB1B are key components of the Hippo signaling pathway and are mutated or inactivated in many human cancers. Here we show that intact Mob1a or Mob1b is essential for murine embryogenesis and that loss of the remaining WT Mob1 allele in Mob1a(Δ/Δ)1b(tr/+) or Mob1a(Δ/+)1b(tr/tr) ...
Lee Scott A - - 2012
Raman spectroscopy is used to probe the nature of the hydrogen bonds which hold the water of hydration to DNA. The ∼ 3450 cm(-1) molecular O-H stretching mode shows that the first six water molecules per base pair of the primary hydration shell are very strongly bound to the DNA. The ...
Rosendaal Frits R - - 2012
The official journal of the International Society on Thrombosis and Haemostasis (ISTH) has an interesting history. It all began when in 1959 the journal Thrombosis et Diathesis Haemorrhagica, which existed since 1957, became associated with the predecessor of the ISTH (i.e. the International Committee on the Nomenclature of the Blood ...
Huang Xianhong - - 2012
A new selective and sensitive fluorescence turn-on detection of CN(-) is reported by taking advantage of aggregation induced-emission (AIE) behavior of tetraphenylethylene units and the nucleophilic attack of CN(-) on the indolium group in compound .
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