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Janssen Ralf - - 2012
Abnormally developing embryos (ADEs) of the common pill millipede Glomeris marginata have been investigated by means of nuclear staining and mRNA in situ hybridization. It showed that all ADEs represent cases of Duplicitas posterior, which means that the posterior body pole is duplicated. The severity of the duplication ranges from ...
He Wenqi - - 2012
We propose a method to achieve the purpose of hierarchical authentication on the basis of two beams' interference and the one-way hash function. For this security protection system, only if the "phase key" and the password-controlled "phase lock" of a user are verified simultaneously can one obtain a permission to ...
Zhang Lihua - - 2012
The objective of the study is to investigate the mechanisms of cyclophosphamide sequential therapy for patient with primary Sjögren's syndrome-associated interstitial lung disease (PSS-ILD). This was a retrospective review of 15 patients (2005-2008) with PSS-ILD who underwent cyclophosphamide sequential therapy. Peripheral blood and bronchoalveolar lavage (BALF) were obtained before and ...
Korkmaz T - - 2012
PURPOSE: Small cell lung cancer (SCLC) has a high relapse rate despite being very chemosensitive. The efficacy of second-line treatment is dismal. Our aim was to evaluate the outcome of second-line treatment. METHODS: We retrospectively assessed data of 120 SCLC patients who failed first-line treatment and received second-line treatment at ...
Alatise Olusegun Isaac - - 2012
PURPOSE: The aim of this study was to determine the length of the sigmoid colon and sigmoid mesocolon in living subjects and fresh cadavers. METHODS: The subjects for the study were consecutive 50 living subjects undergoing abdominal surgeries via midline incision and 50 fresh cadavers undergoing a medicolegal postmortem at ...
Liu Chuan - - 2012
Published data regarding the association between the apurinic/apyrimidinic endonuclease 1 (APE1) Asp148Glu polymorphism and bladder cancer risk showed inconclusive results. This meta-analysis of literatures was performed to draw a more precise estimation of the relationship. We systematically searched PubMed, Embase, Elsevier and Springer for relevant articles with a time limit ...
Peiris Sasanthi - - 2012
We describe the mathematical model and present simulation results for the optimization of a hybrid Raman/optical parametric amplifier (HROPA), exhibiting a bandwidth of 170 nm and low ripple that covers the top half of the wavelength plan (e.g., 1441 to 1611 nm) of next generation coarse wavelength division multiplexed passive optical network ...
Uysal Mehmet Atilla - - 2012
INTRODUCTION: Current guidelines focus more on levels of asthma control than on severity of asthma. The original version of the Asthma Control Test (ACT), a self-administered instrument to determine asthma control levels, was designed for English-speaking patients. More recently, the ACT has been translated into many languages and has been ...
den Daas Izaak - - 2012
BACKGROUND/AIM: Timed interval cerebrospinal fluid (CSF) sampling by indwelling catheterization can be a valuable corroborative tool for the pharmacokinetic and pharmacodynamic assessment of drugs. CSF sampling in studies on drug candidates for Alzheimer's disease have been conducted in evaluations of the biomarkers acetylcholine (ACh), tau proteins, amyloid precursor protein and ...
Procópio Luciano - - 2012
The draft genome of the soil actinomycete Dietzia cinnamea P4 reveals a versatile group of α/β-hydrolase fold enzymes. Phylogenetic and comparative sequence analyses were used to classify the α/β-hydrolases of strain P4 into six different groups: (i) lipases, (ii) esterases, (iii) epoxide hydrolases, (iv) haloacid dehalogenases, (v) C-C breaking enzymes ...
Huang Yao-Han - - 2012
In this study, a Fresnel lens with radial and azimuthal liquid crystal (LC) alignments in the odd and even zones was fabricated using the photoalignment technique based on an azo dye doped in LC cells. The lens has approximately 35% focusing efficiency as determined using a linearly polarized probe beam. ...
Gibson Rachel J - - 2012
PURPOSE: The aim of this study was to review the available literature and define clinical practice guidelines for the use of agents for the prevention and treatment of gastrointestinal mucositis. METHODS: A systematic review was conducted by the Mucositis Study Group of the Multinational Association of Supportive Care in Cancer/International ...
Tanaka Nobukazu - - 2012
The image quality and potential usefulness for patient skin-dose reduction of a newly developed flat-panel detector (FPD) system employing irradiation side sampling (ISS) were investigated and compared to a conventional computed radiography (CR) system. We used the X-ray beam quality of RQA 9 as noted in the standard evaluation method ...
Hellio le Graverand Marie-Pierre - - 2012
OBJECTIVE: To determine if inhibition of inducible nitric oxide synthase (iNOS) with cindunistat hydrochloride maleate slows progression of osteoarthritis (OA) METHODS: This 2-year, multinational, double-blind, placebo-controlled trial enrolled patients with symptomatic knee OA (Kellgren and Lawrence Grade (KLG) 2 or 3). Standard OA therapies were permitted throughout. Patients were randomly ...
Gu Haidong - - 2012
Brillouin frequency shift (BFS) in a single-mode optical fiber has been measured as a function of both radial and axial strain via the Brillouin optical time domain analysis technique. The effects of the two kinds of strain on the BFS are decoupled by making fiber pretensioned and relaxed while applying ...
Vlahović Milena - - 2012
Heavy metals damage the structure, chemistry, and function of cells, including enzyme systems inside them. Variation in the profile of biochemical biomarkers in prevalent species should be used for assessing environmental contamination. The present study pays attention to the phosphatases present in the midgut of gypsy moth fourth instar caterpillars, ...
Kyriazis Iason - - 2012
PURPOSE: To evaluate the effect of vardenafil on renal function after renal ischemia-reperfusion (IR) injury (IRI) in a rat model. MATERIALS AND METHODS: Seventy-one Wistar rats were divided into 7 groups including (1) a vehicle-treated group, (2) a vehicle pretreated-IR group, (3-6) vardenafil pretreated-IR groups in doses of 0.02, 0.2, ...
Bacaër Nicolas - - 2012
For a certain class of multi-type branching processes in a continuous-time periodic environment, we show that the extinction probability is equal to (resp. less than) 1 if the basic reproduction number [Formula: see text] is less than (resp. bigger than) 1. The proof uses results concerning the asymptotic behavior of cooperative systems ...
Liang Xu - - 2012
AIM: This study was designed to explore the genetic polymorphism of IL-10 (-1082A/G, -592A/C, -819T/C), TNF-α (-308G/A) with susceptibility to docetaxel-induced liver injury (DILI) in Chinese breast cancer patients. METHODS: The targeted genetic polymorphisms of IL10-1082G/A, IL10-592A/C, IL10-819T/C, TNF-308G/A from 40 patients with DILI were assayed by matrix-assisted laser desorption/ionization-time ...
Takesue Yoshio - - 2012
To investigate the trends of antimicrobial resistance in pathogens isolated from surgical site infections (SSI), a Japanese surveillance committee conducted the first nationwide survey. Seven main organisms were collected from SSI at 27 medical centers in 2010 and were shipped to a central laboratory for antimicrobial susceptibility testing. A total ...
Li Dawei - - 2012
Working memory (WM) capacity limit has been extensively studied in the domains of visual and verbal stimuli. Previous studies have suggested a fixed WM capacity of typically about three or four items, on the basis of the number of items in working memory reaching a plateau after several items as ...
Wilshire Candice L - - 2012
BACKGROUND: Current diagnostic techniques establishing gastroesophageal reflux disease as the underlying cause in patients with respiratory symptoms are poor. Our aim was to provide additional support to our prior studies suggesting that the association between reflux events and oxygen desaturations may be a useful discriminatory test in patients presenting with ...
Jamison Andrew C - - 2012
Self-assembled monolayers (SAMs) were prepared from a novel two-tailed partially-fluorinated thiol (F8C11:C16), possessing one hydrocarbon chain and one chain with an extended fluorinated segment, and from mixtures of F8C11:C16 and hexadecanethiol (C16) on gold, with the expectation that the internal chemical dissimilarity and wedge-like shape of F8C11:C16 would lead to ...
Mizia-Stec Katarzyna - - 2012
Copeptin is a new biomarker of cardiovascular diseases. Its diagnostic value in degenerative aortic valve stenosis (AS) with preserved left ventricle systolic function is unknown. We aimed to assess the association of serum copeptin levels with AS severity and coexistence of coronary artery disease (CAD). Sixty-four patients with AS and ...
Xu Lin - - 2012
During a study of the diversity and phylogeny of rhizobia isolated from root nodules of Oxytropis ochrocephala grown in the northwest of China, four strains were classified in the genus Rhizobium on the basis of their 16S rRNA gene sequences. These strains have identical 16S rRNA gene sequences, which showed ...
Hao Wei-Hua - - 2013
The chemotherapy agent gemcitabine is currently administered intravenously because the drug has poor oral bioavailability. In order to assess the pharmacokinetics and antitumor activity of D07001-F4, a new self-microemulsifying oral drug delivery system preparation of gemcitabine, this study was performed to compare the effect of D07001-F4 with administered gemcitabine in ...
Otgonsuren Munkhzul - - 2013
Nonalcoholic fatty liver disease (NAFLD) is the hepatic manifestation of metabolic syndrome and may be associated with increased mortality. Our aim was to determine whether anthropometric measures are independently associated with mortality in NAFLD. The third National Health and Nutrition Examination Surveys (1988-1994) data was used. Extensive radiologic, serologic and ...
Chien A Jo - - 2013
The widespread use of trastuzumab in the past decade has led to a significant and measureable improvement in the survival of patients with human epidermal growth factor receptor-2 (HER2) overexpressing breast cancer, and in many ways has redefined the natural history of this aggressive breast cancer subtype. Historically, survival in ...
Gozdowska Magdalena - - 2012
In this study, for the first time, both neuropeptides isotocin (IT) and arginine vasotocin (AVT) have been identified and measured in urophysis, the neurohaemal organ of the caudal neurosecretory system of teleost fish. So far, AVT, but not IT, was quantified by radioimmunoassay (RIA) in urophysis of several fish species. ...
Senst Christiane - - 2013
Breast cancer tissue is a heterogeneous cellular milieu comprising cancer and host cells. The interaction between breast malignant and non-malignant cells takes place in breast tumor microenvironment (TM), and has a crucial role in breast cancer progression. In addition to cellular component of TM, it mainly consists of cytokines released ...
Becker Michael A - - 2012
OBJECTIVE: To evaluate the long-term safety (up to 3 years) of treatment with pegloticase in patients with refractory chronic gout. METHODS: This open-label extension (OLE) study was conducted at 46 sites in the USA, Canada and Mexico. Patients completing either of two replicate randomised placebo-controlled 6-month trials received pegloticase 8 ...
de Paula Eneida - - 2012
One of the most common strategies for pain control during and after surgical procedures is the use of local anesthetics. Prolonged analgesia can be safely achieved with drug delivery systems suitably chosen for each local anesthetic agent. This review considers drug delivery formulations of local anesthetics designed to prolong the ...
Delgado-Montero Antonia - - 2012
Hypertension (HTN) and dyslipemia (DYL) are two of the major modifiable cardiovascular (CV) risk factors, determinants in the development of cerebrovascular and coronary heart disease (CHD). Many patients have both risk factors which increase their total CV risk compared with patients with only one risk factor. Treatment guideline recommendations are ...
Chandra Nagasuma - - 2013
Advances in genomics technologies are providing a very large amount of data on genome-wide gene expression profiles, protein molecules and their interactions with other macromolecules and metabolites. Molecular interaction networks provide a useful way to capture this complex data and comprehend it. Networks are beginning to be used in drug ...
Sun Chun-Yi - - 2013
Metal-organic frameworks (MOFs) are a unique class of hybrid porous solids based on metals and organic linkers. Compared to traditional porous materials, they possess predominance of large surface areas, tunable pore size and shape, adjustable composition and functionalized pore surface, which enable them unique advantages and promises for applications in ...
Gupta Subash C - - 2013
Extensive research over the past half century has shown that curcumin (diferuloylmethane), a component of the golden spice turmeric (Curcuma longa), can modulate multiple cell signaling pathways. Extensive clinical trials over the past quarter century have addressed the pharmacokinetics, safety, and efficacy of this nutraceutical against numerous diseases in humans. ...
Rottschy C - - 2012
In a previous meta-analysis across almost 200 neuroimaging experiments, working memory for object location showed significantly stronger convergence on the posterior superior frontal gyrus, whereas working memory for identity showed stronger convergence on the posterior inferior frontal gyrus (dorsal to, but overlapping with Brodmann's area BA 44). As similar locations ...
Helton William S WS Department of Psychology, University of Canterbury, Private Bag 4800, Christchurch, New Zealand. - - 2013
In this study, we examined the impact of concurrent verbal and visuospatial working memory demands on performance of a visuospatial successive target detection task. Three hundred and four participants performed a visuospatial vigilance task while simultaneously performing either a spatial or verbal working memory task that either required a memory ...
Li Quan Q Department of Orthopedics, Changhai Hospital, 168 Changhai Road, Yangpu District, Shanghai 200433, China. - - 2013
Hypothesis that loss of integrity of the membranes in the craniocervical junction might be the cause of neck pain in patients with whiplash-associated disorders (WADs) has been proposed. In recent years, with development of more detailed magnetic resonance imaging (MRI) techniques, morphologic changes of the ligaments and membranes in the ...
Winter Anke C AC Division of Preventive Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, 900 Commonwealth Avenue East, Boston, MA 02215, USA. - - 2013
Previous studies have suggested that migraineurs are at decreased risk for developing breast cancer. Further prospective studies are warranted to confirm these results. In addition, studies evaluating migraine characteristics (e.g., migraine subtypes and frequency) are lacking. We conducted a prospective cohort study among 39,696 participants in the Women's Health Study ...
Lenz Mark M AO Research Institute Davos, Davos-Platz, Switzerland. - - 2013
Cerclage technology is regaining interest due to the increasing number of periprosthetic fractures. Different wiring techniques have been formerly proposed and have hibernated over years. Hereby, they are compared to current cerclage technology. Seven groups (n = 6) of different cable cerclage (Ø1.7 mm, crimp closure) configurations (one single cerclage looped once ...
Qiao Jun J Department of Spine Surgery, The Affiliated Drum Tower Hospital of Nanjing University Medical School, Zhongshan Road 321, Nanjing 210008, - - 2013
The purpose of this study was to investigate the incidence of neural axis abnormalities in patients with presumed "idiopathic" thoracolumbar or lumbar scoliosis by magnetic resonance imaging (MRI) and try to determine which clinical and radiographic characteristics correlate with neural axis abnormalities on MRI in these patients. The database of ...
Mukamal K J KJ Division of General Medicine and Primary Care, Beth Israel Deaconess Medical Center, 1309 Beacon Street, Brookline, MA 02446, USA. - - 2013
We sought to derive and validate a cardiovascular disease (CVD) prediction algorithm for older adults with diabetes, and evaluate the incremental benefit of adding novel circulating biomarkers and measures of subclinical atherosclerosis. As part of the Cardiovascular Health Study (CHS), a population-based cohort of adults aged ≥65 years, we examined the ...
Dabaghzadeh Fatemeh F Tehran University of Medical Sciences, Department of Clinical Pharmacy, Faculty of Pharmacy, Enghelab Ave, Tehran, - - 2012
More than 50% of HIV-positive patients experience neuropsychiatric adverse reactions following efavirenz therapy. Discontinuation of efavirenz due to its neuropsychiatric side effects has been reported in 2 - 13% of patients. Dizziness, headache, nightmares, abnormal dreams, mild cognitive difficulty, sleep disturbance (somnolence and insomnia), impaired concentration, depression, hallucination, delusion, paranoia, ...
Hendler Karen K Department of Surgery, Division of Pediatric Ophthalmology, Olive View-UCLA Medical Center, 100 Stein Plaza, Los Angeles, CA 90095, USA. - - 2013
To evaluate the effects of inferior oblique muscle recession (IOR) in cases of laterally incomitant hypertropia <10 prism dioptres (PD) in central gaze thact 2t are clinically consistent with superior oblique palsy (SOP). We retrospectively reviewed patients with SOP and hypertropias <10 PD in central gaze who underwent graded IOR. ...
Stokholm Jette J Memory Disorders Research Group, Department of Neurology, Rigshospitalet, Copenhagen University Hospital, N6702, 9 Blegdamsvej, Copenhagen 2100, Denmark. - - 2013
A longitudinal study spanning over 8 years and including 17 asymptomatic individuals with CHMP2B mutations was conducted to assess the earliest neuropsychological changes in autosomal dominant neurodegenerative disease frontotemporal dementia (FTD) linked to chromosome 3 (FTD-3). Subjects were assessed with neuropsychological tests in 2002, 2005 and 2010. Cross-sectional analyses showed ...
Flouzat-Lachaniette Charles-Henri CH Hôpital Henri MONDOR, AP-HP-UPEC, Institut du Rachis, Service de Chirurgie Orthopédique et Traumatologique, 51, avenue du Maréchal de Lattre de Tassigny, 94010 Creteil Cedex, France. - - 2013
To analyze the neurological and mechanical outcomes in 44 consecutive patients treated for a hematological malignancy with epidural localization to assess the place of surgery in the treatment of this pathology. Clinical records, CT and MRI scans of 44 patients with epidural localizations of multiple myeloma or lymphoma treated between ...
Gancarz Amy M AM Department of Psychology, State University of New York at Buffalo, Park Hall Room 204, Buffalo, NY 14260, USA. - - 2013
The ability of locomotor activity in a novel environment (Loco) and visual stimulus reinforcement (VSR) to predict acquisition of responding for cocaine and water reinforcers in the absence of explicit audiovisual signals was evaluated. In Experiment 1 (Exp 1), rats (n = 60) were tested for VSR, followed by Loco, and finally ...
Böttner Martina M Institute of Anatomy, Christian-Albrechts-University of Kiel, , Kiel, - - 2013
Disturbances of the enteric serotonergic system have been implicated in several intestinal motility disorders. Patients with diverticular disease (DD) have been reported to exhibit abnormal intestinal motility and innervation patterns. Gene expression profiles of the serotonergic system and distribution of the serotonin type 4 receptor (5HT-4R) were thus studied in ...
Shulgina Ludmila L Norwich Medical School, University of East Anglia, Norwich, - - 2013
Idiopathic pulmonary fibrosis (IPF) is a fatal condition with limited treatment options. However, in a previous small study, co-trimoxazole was found to be beneficial. In a double-blind multicentre study, 181 patients with fibrotic idiopathic interstitial pneumonia (89% diagnosed as definite/probable IPF) were randomised to receive co-trimoxazole 960 mg twice daily ...
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