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Results 601 - 650 of 4626
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Koczywas Marianna M Medical Oncology and Therapeutics Research, City of Hope, Duarte, CA, - - 2013
Emerging evidence supports the integration of palliative care concurrently with disease-focused care in patients with serious illnesses, such as lung cancer. This paper describes how longitudinal changes in physical function, symptom burden, and QOL of patients with early-stage non-small cell lung cancer (NSCLC) informed the development of an interdisciplinary, tailored ...
Calvo F A - - 2012
INTRODUCTION: To report feasibility, tolerance, anatomical sites of upper abdominal locoregional recurrence and long-term outcome of gastric cancer patients treated with surgery and a component of intraoperative electron beam radiotherapy (IORT). MATERIALS AND METHODS: From January 1995 to December 2010, 32 patients with primary gastric adenocarcinoma treated with curative resection ...
Han Juan - - 2012
Ionic liquid-salt aqueous two-phase extraction coupled with high-performance liquid chromatography with ultraviolet detection was developed for the determination of sulfonamides in water and food samples. In the procedure, the analytes were extracted from the aqueous samples into the ionic liquid top phase in one step. Three sulfonamides, sulfamerazine, sulfamethoxazole, and ...
Becker Michael A - - 2012
OBJECTIVE: To evaluate the long-term safety (up to 3 years) of treatment with pegloticase in patients with refractory chronic gout. METHODS: This open-label extension (OLE) study was conducted at 46 sites in the USA, Canada and Mexico. Patients completing either of two replicate randomised placebo-controlled 6-month trials received pegloticase 8 ...
Fernández-Lizarbe E - - 2012
PURPOSE: The aim of this study was to demonstrate feasibility and analyze dosimetric differences in prone and supine position breast cancer radiotherapy in women with large or pendulous breast. METHODS: Ten post-lumpectomy breast cancer patients underwent supine and prone computed tomography-based treatment plan. On each data set, the whole breast, ...
Lo Pizzo Marianna - - 2012
Distribution of aquaporin-4 (AQP4) was studied by western analysis and immunofluorescence in rat astrocytes exposed to either hypothermic (30 °C) or hyperosmolar (0.45 M sucrose) stress, and in the cerebrospinal fluid (CSF) of patients who suffered traumatic brain injury (TBI). CSF was obtained from 5 healthy subjects and from 20 patients suffering ...
Katz Evgeny - - 2012
This review outlines advances in designing modified electrodes with switchable properties controlled by various physical and chemical signals. Irradiation of the modified electrode surfaces with various light signals, changing the temperature of the electrolyte solution, application of a magnetic field or electrical potentials, changing the pH of the solutions, and ...
Kaneoka Yuji - - 2012
PURPOSE: To investigate the quality of life and venous function of the lower limbs after right external iliac vein (REIV) grafting for digestive surgery. METHOD: The study subjects included 66 patients treated surgically for hepatopancreatobiliary malignancy who underwent concomitant resection with REIV for use as autologous grafts. Fifteen patients completed ...
Janssen Ralf - - 2012
Abnormally developing embryos (ADEs) of the common pill millipede Glomeris marginata have been investigated by means of nuclear staining and mRNA in situ hybridization. It showed that all ADEs represent cases of Duplicitas posterior, which means that the posterior body pole is duplicated. The severity of the duplication ranges from ...
Hata Masayuki - - 2012
BACKGROUND/AIMS: To investigate the causes of isolated fourth nerve palsy (IFNP) and the association among aetiology, prognosis and ocular deviation. METHODS: A total of 126 consecutive cases of IFNP was retrospectively reviewed. According to aetiologies, all patients were classified into five groups: microvascular, congenital, decompensation of congenital, traumatic and others. ...
Francisco Rodríguez Castellanos RC Department of Nephrology, National Institute of Cardiology "Ignacio Chávez", Juan Badiano No. 1, Col Sección XVI, Tlalpan, CP 14080, Mexico City, DF, Mexico, - - 2013
Cardiovascular disease is the leading cause of mortality in patients with chronic kidney disease and has a strong association with hyperphosphatemia. Dialysis is the major treatment tool for attaining serum phosphorus control. Phosphorus removal can be increased with hemodiafiltration. We compared the effect of hemodiafiltration and hemodialysis on serum phosphorus ...
Hulmán A - - 2012
AIMS/HYPOTHESIS: We aimed to study diurnal variation in glucose regulation by examining the effects of time of day and fasting duration on fasting plasma glucose (FPG), 2 h post-load plasma glucose (2hPG) and HbA(1c) levels. METHODS: We analysed data from 5,978 non-diabetic white men and women from the prospective Whitehall II ...
Hoorn Ewout J - - 2012
Disorders of calcium and magnesium balance are physiologically interesting and clinically challenging. In this review, we attempt to bridge the gap between physiology and practice by providing a physiology-based approach to understanding hypocalcemia, hypercalcemia and hypomagnesemia. Calcium and, to a lesser extent, magnesium balance is achieved through a complex interplay ...
Kiss Monika - - 2012
We studied whether visual search for targets defined by a combination of features from different dimensions is guided by separately represented target features or by an integrated representation of the target objects. In Experiment 1, participants searched for target singleton bars that were defined by a specific combination of color ...
Pilgrim Thomas - - 2012
Peri-procedural bleeding complications are feared adverse events in patients undergoing transcatheter aortic valve implantation (TAVI). Little is known about the implications of peri-procedural bleeding on clinical outcome. In a prospective single-center registry of consecutive patients undergoing TAVI, we investigated incidence, predictors and clinical consequences of life-threatening and major bleeding as ...
Marmotti A - - 2012
PURPOSE: Minced chondral fragments are becoming popular as a source of cells for cartilage repair, as a growing interest is developing towards one-stage procedures to treat cartilage lesions. The purpose of this study is to (A) compare cell outgrowth from cartilage fragments of adult and young donors using two different ...
Pandey Usha - - 2012
Investigations on periphyton along an eutrophication gradient (NO(3) (-) = 0.23-0.96 mg L(-1); PO (4) (-3)  = 0.16-0.86 mg L(-1)) of Ganga River indicated that benthic algal biomass decreased with increasing concentrations of nutrients and dissolved organic carbon (DOC). Periphyton biomass showed negative relationship (R (2) = 0.98; p < 0.0001) with DOC and positive relationship (R (2) = 0.96; p < 0.0001) ...
Xiong Yule - - 2012
We theoretically investigate for the first time an all-optical switch using a silicon-based ring-assisted Mach-Zehnder interferometer (RAMZI), where the switch mechanism relies on Raman-induced loss. Compared to the conventional standalone microring resonator (MRR) switches, the RAMZI structure improves the fabrication tolerances by removing the critical coupling requirement for the MRR ...
Bhatti Shaukat Ali - - 2012
The objective of present study was to evaluate the growth potential of Sahiwal calves for veal production on whole milk or whole milk and milk replacer combined in a ratio of 50:50 (MMR). For this purpose, 48 Sahiwal calves (both male and female) were assigned to four dietary treatments having ...
Oncel Selim - - 2012
We have chosen Google, which is the most widely used search engine, to simulate a parent's experience in trying to find an answer on whether to have her/his child vaccinated against influenza. In doing this, we aimed to find out the chances that a parent with usual Internet searching tendencies ...
Ertekin Tolga - - 2012
PURPOSE: The subcortical brain structures are associated with other structures of nervous system; therefore, they have major influence on sensory-motor, limbic and cognitive information processing. Magnetic resonance imaging provides a detailed knowledge of normal and diseased anatomical structures for medical research. The aim of the current study was to compare ...
Ozolina Natalia V - - 2012
The experiments conducted on tonoplast of Beta vulgaris L. roots were performed to identify detergent-resistant lipid-protein microdomains (DRMs, interpreted as lipid rafts).The presence of DRMs can be found when dynamic clustering of sphingolipids, sterols, saturated fatty acids is registered, and the insolubility of these microdomains in nonionic detergents at low ...
Freischmidt Axel - - 2012
Cell-free synthesis of recombinant proteins has emerged as an alternative method of protein production although protein yields still cannot compete with in vivo expression techniques. In systems based on S30 extracts of Escherichia coli unfavorable side-reactions are involved in limiting protein yields. Therefore, carrying out cell-free reactions at lower temperatures ...
Mercuri Jeremy - - 2012
Nucleus pulposus (NP) tissue regeneration has been proposed as an early-stage interventional therapy to combat intervertebral disc degeneration. We have previously reported on the development and characterization of a novel biomimetic acellular porcine nucleus pulposus (APNP) hydrogel. Herein we aimed to evaluate this material for use as a suitable scaffold ...
An Rong Rong - - 2012
The influence of the elastic modulus of a tumor (EMT) on the laser-generated thermoelastic force source and ultrasound waves are investigated by using the finite element method. Taking into account the effects of thermal diffusion, optical penetration, and finite duration of laser pulse, the transient temperature distribution is obtained. Applying ...
Mudhar Hardeep Singh - - 2012
BACKGROUND/AIMS: A retrospective service evaluation identified seven patients who developed local conjunctival metastases (LCMs) of the conjunctiva after a primary diagnosis of conjunctival invasive melanoma. The study was conducted to identify the clinico-pathological characteristics and implications of these LCMs. METHODS: Seven patients with primary conjunctival melanoma seen by the ocular ...
Jin Ke K Jiangsu Province Key Laboratory in Infectious Diseases, The First Affiliated Hospital of Nanjing Medical University; Nanjing, - - 2013
A DNA vaccination approach was used in the current study to screen for the immunogenicity of different fragments of toxin A and toxin B from Clostridium difficile. With this approach, protein antigens do not need to be produced in vitro and the immunogenicity of candidate C. difficile antigens can be ...
Lomas R J - - 2012
The objective of this study was to design and test a protocol for the validation of banking methodologies for arterial allografts. A series of in vitro biomechanical and biological assessments were derived, and applied to paired fresh and banked femoral arteries. The ultimate tensile stress and strain, suture pullout stress ...
Bailly Xavier X UPMC-CNRS, FR2424, Station Biologique de Roscoff, France. - - 2013
Flatworms are classically considered to represent the simplest organizational form of all living bilaterians with a true central nervous system. Based on their simple body plans, all flatworms have been traditionally grouped together in a single phylum at the base of the bilaterians. Current molecular phylogenomic studies now split the ...
Ichida Hirofumi - - 2012
BACKGROUND: We assessed the benefit of hepatic and pulmonary resections in patients with liver and lung recurrences, respectively, after resection of esophageal carcinoma. METHODS: The study population consisted of 138 consecutive patients with recurrent esophageal carcinoma after esophagectomy conducted between 2003 and 2005. The pattern, timing of appearance, and the ...
Ghorbanpour Mohammad - - 2012
It is demonstrated that any theoretical analysis of experimental surface plasmon resonance (SPR) curves of metallic nano bilayers preferably should be accompanied by a more sensitive technique that is less prone to experimental errors. Micro energy dispersive x-ray fluorescence has been shown to be a powerful technique for predicting SPR ...
Schwarz Marcus A - - 2012
According to popular models of human time perception, variations in prospective timing are caused by two factors: the pulse rate of an internal pacemaker and the amount of attention directed to the passage of time. The results concerning the effect of attention on subjective timing have been conclusive, but the ...
Tello-Montoliu Antonio - - 2012
Ischemic heart disease is uncommon during pregnancy, occurring in approximately 1/10,000 pregnancies resulting in live births. However, the increased age and fertility of mothers has suggested that the coexistence of pregnancy and coronary artery disease is likely to increase. A subject of debate is the management of dual antiplatelet therapy ...
Tomizawa Nobuo - - 2012
Our aim was to investigate when halfcycle reconstruction (HCR) was feasible in patients who were predicted to have a heart rate over 65 bpm in coronary CT angiography (CTA) using 320-row CT. Seventy-four patients who underwent multiple heart beat scanning were included. The time to reach 230 HU at the ascending aorta ...
Klinz Franz-Josef - - 2012
A wide variety of stimuli can trigger activation of the transcription factor CREB (cAMP-responsive element binding protein), pointing toward a central role for CREB in the integration of various signaling inputs. No data are available on the expression and phosphorylation of CREB in mammalian teeth. Using immunohistochemical analysis of free-floating ...
Wu Ting-Yu - - 2012
PURPOSE: To evaluate the effects of gas tamponade without vitrectomy in patients with myopic foveoschisis and foveal detachment. METHODS: We examined 10 eyes of 10 patients with myopic foveoschisis and foveal detachment. All patients received an intravitreal injection of 0.2-0.4 mL C3F8 and remained in the prone position for 5 to ...
Hohenberger Werner - - 2012
PURPOSE: For many years, the impact of the surgeon volume on short- and long-term outcome after rectal carcinoma surgery is controversially discussed. Literature and own department data were reviewed in order to clarify the impact of surgeon volume in the current era of total mesorectal excision surgery, multimodal therapy, quality ...
Morgan B - - 2012
Post-mortem computed tomography with coronary angiography (PMCTA) could have a role in the investigation of sudden natural death. This study assesses the accuracy of targeted coronary PMCTA, using both air and iodinated contrast media, to provide sensitivity and specificity for critical stenosis (CS) on a segmental basis, based on a ...
Brouwer Matthijs C - - 2012
Rapid diagnosis and treatment of acute community-acquired bacterial meningitis reduces mortality and neurological sequelae, but can be delayed by atypical presentation, assessment of lumbar puncture safety, and poor sensitivity of standard diagnostic microbiology. Thus, diagnostic dilemmas are common in patients with suspected acute community-acquired bacterial meningitis. History and physical examination ...
- - 2012
A debate at this year's BVA Congress considered the increasing proportion of women in the veterinary profession and the implications this could have. It also sought to dispel some of the myths surrounding women in the workplace. Georgina Mills reports.
Oner Veysi - - 2012
AIM: To evaluate the influence of axial length on retinal nerve fibre layer (RNFL) thickness in myopic, hyperopic and emmetropic eyes by spectral domain optical coherence tomography (OCT). METHODS: Subjects were divided into three groups: myopic (n=35), emmetropic (n=30) and hyperopic eyes (n=33). RNFL thickness was obtained from all octametric ...
Persson Inga-Lill - - 2012
We have addressed the impact of moose (Alces alces L.) on accumulation of secondary metabolites, lignin, and nitrogen in bilberry (Vaccinium myrtillus L.) along gradients of habitat productivity and solar radiation. The study was conducted within a long-term research project on direct and indirect impacts of moose on the ecosystem. ...
Bahillo Jose - - 2012
PURPOSE: The purpose of this study is to assess the marginal adaptation of cavities restored with a three-step etch-and-rinse adhesive, OptiBond FL (OFL) under different application protocols. MATERIALS AND METHODS: Twenty-four class V cavities were prepared with half of the margins located in enamel and half in dentin. Cavities were ...
Slade Peter G - - 2012
Chinese hamster ovary cells (CHO) are the most common cell line used in the production of therapeutic proteins. Understanding the complex pattern of secreted host cell proteins (HCP) that are released by CHO cells will facilitate the development of new recombinant protein production processes. In this study we have adapted ...
Gancarz Amy M AM Department of Psychology, State University of New York at Buffalo, Park Hall Room 204, Buffalo, NY 14260, USA. - - 2013
The ability of locomotor activity in a novel environment (Loco) and visual stimulus reinforcement (VSR) to predict acquisition of responding for cocaine and water reinforcers in the absence of explicit audiovisual signals was evaluated. In Experiment 1 (Exp 1), rats (n = 60) were tested for VSR, followed by Loco, and finally ...
Faillace Meghan E - - 2012
Mineralizing osteoblasts are regularly used to study osteogenesis and model in vivo bone formation. Thus, it is important to verify that the mineral and matrix being formed in situ are comparable to those found in vivo. However, it has been shown that histochemical techniques alone are not sufficient for identifying ...
Dunlop Sally M - - 2012
BACKGROUND: The necessary first steps for televised media campaign effects are population exposure and recall. To maximise the impact of campaign funding, it is critical to identify modifiable factors that increase the efficiency of an advertisement reaching the target audience and of their recalling that advertisement. METHODS: Data come from ...
Cheah Ker Y - - 2012
BACKGROUND: Grape seed extract (GSE) constitutes a rich source of procyanidins. GSE has been demonstrated to exert encouraging anti-inflammatory and anti-ulcer properties in experimental settings, although its effects on inflammation of the colon remain undefined. AIM: To determine the effects of GSE in a rat model of dextran sulphate sodium ...
Hsiao H-B - - 2012
Kinsenoside is able to improve bone turnover rate in ovariectomized (OVX) mice. In vitro analysis shows that kinsenoside antagonizes osteoclast development and bone resorption. INTRODUCTION: Kinsenoside, the main active compound of the traditional Taiwanese herb Anoectochilus formosanus, has an antiinflammatory effect. This study investigates whether kinsenoside inhibits osteoporosis and osteoclastogenesis. ...
Tu Yabin - - 2012
The porcine circovirus type 2 (PCV2) capsid protein (Cap) is an important antigen for the development of vaccines. To achieve high-level expression of recombinant PCV2 Cap in Pichia pastoris, the wild-type Cap (wt-Cap) and optimized Cap (opti-Cap) gene fragments encoding the same amino acid sequence of PCV2 were amplified by ...
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