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Results 551 - 600 of 4623
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Ritter Markus - - 2012
BACKGROUND AND AIM: To describe the clinical and genetic characteristics of a mother and her son presenting with two distinct and rare forms of retinal degeneration. METHODS: Investigations in both patients comprised spectral domain optical coherence tomography (SD-OCT), fundus autofluorescence imaging, non-contact biometry, ultrasonography, electroretinography (ERG) and analysis of the ...
Vardi Nigar - - 2012
This study was conducted to evaluate a possible protective role of apricot in apoptotic cell death induced by methotrexate (MTX) and renal damage by different histological and biochemical parameters. Twenty-eight rats were divided into four groups, control, apricot, methotrexate, and apricot + methotrexate. Methotrexate induced renal failure, as shown by ...
Zhu Xishan - - 2012
Our aim was to evaluate the therapeutic effects of bone-marrow-derived mesenchymal stem cells (BMMSCs) on ConA-induced hepatitis and to elucidate the possible mechanism involved. MSCs were isolated from bone marrow and their characteristics and anti-apoptotic effects on the L02 cell line were analyzed. The effect of intravenous infusion of BMMSCs ...
Lantos Joshua E - - 2012
Giant cell tumor of the tendon sheath (GCTTS) is one of the most common benign soft tissue tumors in the extremities, and is frequently associated with bone abnormalities. Although extrinsic bone erosion is the most common bone abnormality associated with GCTTS, intraosseous invasion of GCTTS occurs rarely and may mimic ...
Robinson Tracy J - - 2012
High-quality computed tomography (CT) exams are critical to maximizing radiologist's interpretive ability. Exam quality in part depends on proper contrast administration. We examined injector data from consecutive abdominal and pelvic CT exams to analyze variation in contrast administration. Discrepancies between intended IV contrast dose and flow rate with the actual ...
Treutter Dieter - - 2012
The fruits of the European plum Prunus domestica exhibit a great diversity in appearance including the skin colors. This study attempts to elucidate the phenylpropanoid and flavonoid profiles of 28 plum varieties belonging to P. domestica and related species as well as hybrids. A total of 49 phenolic compounds extracted ...
Chhablani Jay - - 2012
BACKGROUND: To evaluate the impact of scanning density on macular choroidal volume measurement using spectral-domain optical coherence tomography (SD-OCT). METHODS: Thirty eyes of normal subjects underwent consecutive raster choroidal scanning protocols using SD-OCT in enhanced-depth imaging mode. Manual choroidal segmentation was performed using the built-in automated retinal segmentation software to ...
Yovcheva Temenuzhka - - 2012
The refractive index (RI) of polymer nanocomposite of poly(vinyl alcohol) films with TiO<sub>2</sub> nanoparticle inclusions with low concentration up to 1.2 wt. % was investigated. Accurate refractometric measurements, by a specially designed laser microrefractometer, were performed at wavelengths 532 and 632.8 nm. The influence of TiO<sub>2</sub> concentration on the RI dispersion curves ...
Son Jun Sik - - 2012
The goal of this study was to develop a functional titanium (Ti) implant loaded with bioactive molecules using biodegradable polymeric particles as drug delivery carrier for dental applications. In this study, dexamethasone (DEX)-loaded poly(lactic-co-glycolic acid) (PLGA) particles were electrostatically immobilized on a Ti disc surface coated with hydroxyapatite (HA) nanocrystals ...
Yilmaz Neslihan - - 2012
Takayasu arteritis (TA) and Crohn's disease (CD) are chronic inflammatory diseases with granulomatous nature. Here, we report a case of TA with a silent course of CD who was refractory to corticosteroid and immunosuppressive treatments and improved with adalimumab therapy.
Nishizawa Yoshiki - - 2012
Recently the clinical application of bone metabolic markers has achieved significant progress and the measurements of these indices give us a better understanding of the pathogenesis of osteoporosis. Bone metabolic markers were adapted to select drug treatment for osteoporosis and to evaluate drug efficacy. Therefore, the proper application and assessment ...
Paban Véronique - - 2012
Inbred LOU/C/Jall rats are currently described as a model of successful aging. These rats have a longer healthy median lifespan than many other strains, do not develop obesity, diabetes, or tumor and more importantly they do not show cognitive decline with aging. This is the first study to examine gene ...
van der Linden Carolien M J - - 2012
BACKGROUND: Earlier studies have shown poor documentation of the reasons for medication discontinuation during hospitalization. Communication of reasons for discontinuation, e.g. adverse drug reactions (ADRs), to general practitioners and pharmacists was also found to be insufficient, leading to a rate of represcription after an ADR of 27 % during the first ...
Uesugi Kazuhiro - - 2012
BACKGROUND: The Wilms' tumor 1 (WT1) gene is known to be overexpressed in hepatocellular carcinoma (HCC) and to upregulate tumor growth and oncogenic potential, although the detailed mechanisms remain to be elucidated. METHODS: We identified host genes involved in WT1 gene modulation of human liver cancer cell lines in vitro, ...
Phull Manraj K - - 2012
The restoration of body contours as shaped by adipose tissue remains a clinical challenge specifically in patients who have experienced loss of contour due to trauma, surgical removal of tumours or congenital abnormalities. We have developed a novel macro-microporous biomaterial for use in soft tissue re-bulking and augmentation. Alginate beads ...
Nehus Edward J - - 2012
BACKGROUND: Limited data exist on the performance of cystatin C-based glomerular filtration rate (GFR) equations in pediatric transplant recipients and other high-risk patients. The aim of our study was therefore to evaluate the performance of current cystatin C-based equations in this population. METHODS: This was a retrospective, cross-sectional study of ...
Oddstig Jenny - - 2012
BACKGROUND: For a 1-day myocardial perfusion SPECT (MPS) the recommendations for administered activity stated in the EANM guidelines results in an effective dose of up to 16 mSv per patient. Recently, a gamma camera system, based on cadmium zinc telluride (CZT) technology, was introduced. This technique has the potential to reduce ...
Vaquero Javier - - 2012
PURPOSE: The purpose of this study was to perform a cross-cultural adaptation of the Knee Injury and Osteoarthritis Outcome Score (KOOS) into Spanish and to evaluate the psychometric properties of this version in patients with chondral lesion of the knee, as expressed by its validity, reliability and responsiveness. METHODS: The ...
Veses Oscar - - 2012
This study was carried out in order to assess potential toxicity of hazardous pollutants (8 trace elements and 8 polycyclic aromatic hydrocarbons) in 20 sediment samples of the Ebro River basin (Spain) sampled in 2009. Mean-probable effect concentration quotient (m-PECQ) was found to range from 0.03 to 0.79. Two sites ...
Okamoto Scott K - - 2012
The purpose of this study was to adapt and validate narrative scripts to be used for the video components of a culturally grounded drug prevention program for rural Native Hawaiian youth. Scripts to be used to film short video vignettes of drug-related problem situations were developed based on a foundation ...
Makey Ghaith - - 2012
This paper introduces a new modification for the well-known binary detour phase method, which is largely used to represent Fourier holograms; the modification utilizes gray scale level control provided by a liquid crystal spatial light modulator to improve the traditional binary detour phase. Results are shown by both simulation and ...
Sheng Guodong - - 2012
This work determined the influence of humic acid (HA) and fulvic acid (FA) on the interaction mechanism and microstructure of Ni(II) onto diatomite by using batch experiments, X-ray photoelectron spectroscopy (XPS), and extended X-ray absorption fine structure (EXAFS) methods. Macroscopic and spectroscopic experiments have been combined to see the evolution ...
Zlotina Anna - - 2012
Chicken (Gallus gallus domesticus, GGA) and Japanese quail (Coturnix coturnix japonica, CCO) karyotypes are very similar. They have identical chromosome number (2n = 78) and show a high degree of synteny. Centromere positions on the majority of orthologous chromosomes are different in these two species. To explore the nature of this divergence, ...
Prabowo Satria A - - 2012
Tuberculosis (TB) has scourged humankind for millennia, and latent infection affects nearly one-third of today's world population. The emergence of multidrug-resistant (MDR)-TB is a major global threat and reflects treatment failure of drug-sensitive disease. MDR-TB management is a burden for patients and society; success rates are unacceptably low with prolonged ...
Papaharilaou Yannis - - 2012
Head and neck postures may cause morphology changes to the geometry of the carotid bifurcation (CB) that alter the low and oscillating wall shear stress (WSS) regions previously reported as important in the development of atherosclerosis. Here the right and left CB were imaged by MRI in two healthy subjects ...
Jurt Simon - - 2012
(15)N relaxation rates of amide moieties provide insight both into global as well as local backbone dynamics of peptides and proteins. As the differences in the relaxation rates in general are small, their accurate determination is of prime importance. One potential source of error is fast amide exchange. It is ...
Oktayoglu Pelin - - 2012
This study was carried out to determine the serum levels of high mobility group box protein 1 (HMGB1) in patients with ankylosing spondylitis (AS) and to evaluate its correlation with disease activity and quality of life. According to our knowledge, it is the first trial evaluating HMGB1 levels in AS. ...
Freynhofer Matthias K - - 2012
Death from coronary artery disease is by far the leading cause of death worldwide. There is no doubt that a better understanding of atherothrombosis has guided development of improved diagnostic facilities as well as revascularization technologies in combination with current antithrombotic strategies that have altogether impressively reduced acute thromboembolic complications ...
Tang J - - 2012
OBJECTIVE: As a small heavily glycosylated mucin-like glycosyl-phosphatidylinositol-anchored cell surface protein, CD24 plays an important role in carcinogenesis of various human malignancies. However, its involvement in osteosarcoma is still unclear. The aim of this study was to investigate the expression pattern and the clinical significance of CD24 in human osteosarcoma. ...
Cheng Hua - - 2012
The cinnamyl alcohol dehydrogenase (CAD) is a key enzyme in lignin biosynthesis as it catalyzes the final step in the synthesis of monolignols. A cDNA sequence encoding the CAD gene was isolated from the leaves of Ginkgo biloba L, designated as GbCAD1. The full-length cDNA of GbCAD1 was 1,494 bp containing ...
Barany Mate - - 2012
The determination of reaction pathways is one of the most important functions that should be performed in exploring the kinetics of catalyzed chemical reactions or biochemical reactions, the latter being generally catalyzed by enzymes. It is proven that the terms, "type-I extreme pathway" and "structurally minimal pathway", both introduced to ...
Zhu Lei - - 2012
The influence of symmetry breaking in a planar metamaterial on transparency effect is numerically investigated. The planar metamaterial's cell is formed by three parallel metal wires. From numerical simulation results, we can see that the transparency effect results from the asymmetric coupling between the cut wires. The excited mechanism of ...
Dikken Johan L - - 2012
BACKGROUND: Survival estimates after curative surgery for gastric cancer are based on AJCC staging, or on more accurate multivariable nomograms. However, the risk of dying of gastric cancer is not constant over time, with most deaths occurring in the first 2 years after resection. Therefore, the prognosis for a patient who ...
Lin Wenfang - - 2012
Microorganism in drinking water distribution system may colonize in biofilms. Bacterial 16S rRNA gene diversities were analyzed in both water and biofilms grown on taps with three different materials (polyvinyl chloride (PVC), stainless steel, and cast iron) from a local drinking water distribution system. In total, five clone libraries (440 ...
Tsutsumi Satoshi - - 2012
PURPOSE: This study aims to investigate the distribution and anatomic features of venous lacuna presenting with unusual upward protrusion (VLUUP) using high-resolution magnetic resonance (MR) imaging. METHODS: This retrospective study included 59 consecutive outpatients who underwent MR imaging with gadolinium. Acquired imaging data were transferred to a workstation for analysis. ...
Hata Masayuki - - 2012
BACKGROUND/AIMS: To investigate the causes of isolated fourth nerve palsy (IFNP) and the association among aetiology, prognosis and ocular deviation. METHODS: A total of 126 consecutive cases of IFNP was retrospectively reviewed. According to aetiologies, all patients were classified into five groups: microvascular, congenital, decompensation of congenital, traumatic and others. ...
Francisco Rodríguez Castellanos - - 2012
BACKGROUND/AIM: Cardiovascular disease is the leading cause of mortality in patients with chronic kidney disease and has a strong association with hyperphosphatemia. Dialysis is the major treatment tool for attaining serum phosphorus control. Phosphorus removal can be increased with hemodiafiltration. We compared the effect of hemodiafiltration and hemodialysis on serum ...
Hulmán A - - 2012
AIMS/HYPOTHESIS: We aimed to study diurnal variation in glucose regulation by examining the effects of time of day and fasting duration on fasting plasma glucose (FPG), 2 h post-load plasma glucose (2hPG) and HbA(1c) levels. METHODS: We analysed data from 5,978 non-diabetic white men and women from the prospective Whitehall II ...
Hoorn Ewout J - - 2012
Disorders of calcium and magnesium balance are physiologically interesting and clinically challenging. In this review, we attempt to bridge the gap between physiology and practice by providing a physiology-based approach to understanding hypocalcemia, hypercalcemia and hypomagnesemia. Calcium and, to a lesser extent, magnesium balance is achieved through a complex interplay ...
Shin Seung-Ho - - 2012
This study examined the indoor concentrations of a wide range of volatile organic compounds (VOCs) in currently built new apartments every month over a 24-month period and the source characteristics of indoor VOCs. The indoor total VOC (TVOC) concentrations exhibited a decreasing tendency over the 24-month follow-up period. Similar to ...
Zhou F Y - - 2012
In this study, the microstructure, mechanical properties, corrosion behaviors, and in vitro biocompatibility of Zr-Mo alloys as a function of Mo content after solution treatment were systemically investigated to assess their potential use in biomedical application. The experimental results indicated that Zr-1Mo alloy mainly consisted of an acicular structure of ...
Ferro Mark A - - 2012
PURPOSE: The aim of this study was to utilize bootstrapping to investigate the robustness of latent class trajectories and risk factors of depressive symptoms among mothers of children with epilepsy. METHODS: Data were obtained from a national prospective cohort study (2004-09) of children newly diagnosed with epilepsy and their families ...
Jacob Anu - - 2012
Neuromyelitis optica (NMO) has been described as a disease clinically characterised by severe optic neuritis (ON) and transverse myelitis (TM). Other features of NMO include female preponderance, longitudinally extensive spinal cord lesions (>3 vertebral segments), and absence of oligoclonal IgG bands . In spite of these differences from multiple sclerosis ...
Liang Xing-Xiang - - 2012
A new approach is described to quantify the number of enzyme molecules, such as Candia antarctica lipase B, that are displayed on the cell surface of Pichia pastoris. Enhanced green fluorescent protein (EGFP) and Candida antarctica lipase B (CALB) were fused and displayed on the surface of P. pastoris by ...
Evans Christopher Charles Douglas - - 2012
OBJECTIVES: Prehospital airway management for adult trauma patients remains controversial. We sought to review the frequency that paramedic non-drug assisted intubation or attempted intubation is performed for trauma patients in Ontario, Canada, and determine its association with mortality. METHODS: We conducted a retrospective cohort study using the Ontario Trauma Registry's ...
Ghorbanpour Mohammad - - 2012
It is demonstrated that any theoretical analysis of experimental surface plasmon resonance (SPR) curves of metallic nano bilayers preferably should be accompanied by a more sensitive technique that is less prone to experimental errors. Micro energy dispersive x-ray fluorescence has been shown to be a powerful technique for predicting SPR ...
Schwarz Marcus A - - 2012
According to popular models of human time perception, variations in prospective timing are caused by two factors: the pulse rate of an internal pacemaker and the amount of attention directed to the passage of time. The results concerning the effect of attention on subjective timing have been conclusive, but the ...
Tello-Montoliu Antonio - - 2012
Ischemic heart disease is uncommon during pregnancy, occurring in approximately 1/10,000 pregnancies resulting in live births. However, the increased age and fertility of mothers has suggested that the coexistence of pregnancy and coronary artery disease is likely to increase. A subject of debate is the management of dual antiplatelet therapy ...
Tomizawa Nobuo - - 2012
Our aim was to investigate when halfcycle reconstruction (HCR) was feasible in patients who were predicted to have a heart rate over 65 bpm in coronary CT angiography (CTA) using 320-row CT. Seventy-four patients who underwent multiple heart beat scanning were included. The time to reach 230 HU at the ascending aorta ...
Klinz Franz-Josef - - 2012
A wide variety of stimuli can trigger activation of the transcription factor CREB (cAMP-responsive element binding protein), pointing toward a central role for CREB in the integration of various signaling inputs. No data are available on the expression and phosphorylation of CREB in mammalian teeth. Using immunohistochemical analysis of free-floating ...
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