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van der Steen Jenny T - - 2012
INTRODUCTION: Families of patients with dementia may need support in difficult end-of-life decision making. Such guidance may be culturally sensitive. METHODS: To support families in Canada, a booklet was developed to aid decision making on palliative care issues. For reasons of cost effectiveness and promising effects, we prepared for its ...
- - 2012
Unusual outbreak of rhinitis in a Jersey herd Pulpy kidney reported by most regional laboratories in four- to six-month-old lambs Swine influenza in batches of weaners with salmonellosis and streptococcal disease Coronavirus infection diagnosed in pheasants with visceral gout and interstitial nephritis Swan mortality associated with duck virus enteritis These ...
Kavšek Michael - - 2012
When making relative distance judgments, adults attend to information provided by the ground surface and generally ignore information provided by ceiling surfaces. In the present study, we asked whether this ground dominance effect is present in infancy. Groups of 5- and 7-month-old infants viewed a display depicting textured ground and ...
Rodríguez-Palomares José F - - 2012
OBJECTIVES: Our study aimed to compare the area at risk (AAR) determined by single-photon emission computed tomography (SPECT) with the Bypass Angioplasty Revascularization Investigation (BARI) and modified Alberta Provincial Project for Outcome Assessment in Coronary Heart Disease (APPROACH) angiographic scores in the setting of patients undergoing coronary angioplasty for either ...
Huntimer Lucas - - 2012
Microparticle adjuvants based on biodegradable polyanhydrides were used to provide controlled delivery of a model antigen, ovalbumin (Ova), to mice. Ova was encapsulated into two different polyanhydride microparticle formulations to evaluate the influence of polymer chemistry on the nature and magnitude of the humoral immune response after administration of a ...
Au Yong Kong Jung - - 2012
BACKGROUND: Supratentorial atypical teratoid rhabdoid tumor (ATRT) in many cases has a distinctive appearance on post-gadolinium MRI. OBJECTIVE: We sought to determine whether this is a unique appearance allowing ATRT to be distinguished accurately from other types of pediatric supratentorial tumors. MATERIALS AND METHODS: Retrospective review of all available preoperative ...
Shin Ga-Yeong - - 2012
PURPOSE: Currently, the interaction between the niche and glioma cancer stem cells (gCSCs) is gaining attention. However, there are few studies concerned with the effects of repeated exposure to a new microenvironment on gCSCs characteristics. In this study, serial in vivo subtransplantation was performed to create a new microenvironment. We ...
Doi Shinpei - - 2012
BACKGROUND: Endoscopic sphincterotomy (ES) is widely performed in patients with common bile duct stones (CBDS). However, the long-term outcomes of patients following ES have not been sufficiently elucidated. Impaired papillary function following ES may result in additional late complications. In contrast, endoscopic papillary balloon dilation (EPBD)-another option for treating CBDS-is ...
Zhang Shengfan - - 2012
The effect of breast density on survival outcomes for American women who participate in screening remains unknown. We studied the role of breast density on both breast cancer and other cause of mortality in screened women. Data for women with breast cancer, identified from the community-based Carolina Mammography Registry, were ...
Flouzat-Lachaniette Charles-Henri CH Hôpital Henri MONDOR, AP-HP-UPEC, Institut du Rachis, Service de Chirurgie Orthopédique et Traumatologique, 51, avenue du Maréchal de Lattre de Tassigny, 94010 Creteil Cedex, France. - - 2013
To analyze the neurological and mechanical outcomes in 44 consecutive patients treated for a hematological malignancy with epidural localization to assess the place of surgery in the treatment of this pathology. Clinical records, CT and MRI scans of 44 patients with epidural localizations of multiple myeloma or lymphoma treated between ...
Oktayoglu Pelin - - 2012
This study was carried out to determine the serum levels of high mobility group box protein 1 (HMGB1) in patients with ankylosing spondylitis (AS) and to evaluate its correlation with disease activity and quality of life. According to our knowledge, it is the first trial evaluating HMGB1 levels in AS. ...
Freynhofer Matthias K - - 2012
Death from coronary artery disease is by far the leading cause of death worldwide. There is no doubt that a better understanding of atherothrombosis has guided development of improved diagnostic facilities as well as revascularization technologies in combination with current antithrombotic strategies that have altogether impressively reduced acute thromboembolic complications ...
Tang J - - 2012
OBJECTIVE: As a small heavily glycosylated mucin-like glycosyl-phosphatidylinositol-anchored cell surface protein, CD24 plays an important role in carcinogenesis of various human malignancies. However, its involvement in osteosarcoma is still unclear. The aim of this study was to investigate the expression pattern and the clinical significance of CD24 in human osteosarcoma. ...
Cheng Hua - - 2012
The cinnamyl alcohol dehydrogenase (CAD) is a key enzyme in lignin biosynthesis as it catalyzes the final step in the synthesis of monolignols. A cDNA sequence encoding the CAD gene was isolated from the leaves of Ginkgo biloba L, designated as GbCAD1. The full-length cDNA of GbCAD1 was 1,494 bp containing ...
Barany Mate - - 2012
The determination of reaction pathways is one of the most important functions that should be performed in exploring the kinetics of catalyzed chemical reactions or biochemical reactions, the latter being generally catalyzed by enzymes. It is proven that the terms, "type-I extreme pathway" and "structurally minimal pathway", both introduced to ...
Rubinson Kenneth A - - 2012
The low-resolution three-dimensional structure of purified native beef heart mitochondrial cytochrome c oxidase (COX) in asolectin unilamellar liposomes has been measured by small-angle neutron scattering under the conditions where the protein remains fully functional. From a neutron scattering perspective, the use of mixed-lipid liposomes provided for a more homogeneous matrix ...
Furuichi Yoshihiro - - 2012
BACKGROUND: Acoustic radiation force impulse (ARFI) elastography is an ultrasound technique that is capable of measuring tissue stiffness noninvasively. It is difficult to differentiate idiopathic portal hypertension (IPH) from liver cirrhosis (LC) or chronic hepatitis (CH), and liver biopsy is essential. We investigated whether it would be possible to noninvasively ...
Urbina Mauricio A - - 2012
Inanga (Galaxias maculatus) is an amphidromous fish with a well-known capacity to withstand a wide range of environmental salinities. To investigate the molecular mechanisms facilitating acclimation of inanga to seawater, several isoforms of the Na(+), K(+)-ATPase ion transporter were identified. This included three α-1 (a, b and c), an α-2 ...
Delgado-Montero Antonia - - 2012
Hypertension (HTN) and dyslipemia (DYL) are two of the major modifiable cardiovascular (CV) risk factors, determinants in the development of cerebrovascular and coronary heart disease (CHD). Many patients have both risk factors which increase their total CV risk compared with patients with only one risk factor. Treatment guideline recommendations are ...
Böttner Martina M Institute of Anatomy, Christian-Albrechts-University of Kiel, , Kiel, - - 2013
Disturbances of the enteric serotonergic system have been implicated in several intestinal motility disorders. Patients with diverticular disease (DD) have been reported to exhibit abnormal intestinal motility and innervation patterns. Gene expression profiles of the serotonergic system and distribution of the serotonin type 4 receptor (5HT-4R) were thus studied in ...
Helton William S WS Department of Psychology, University of Canterbury, Private Bag 4800, Christchurch, New Zealand. - - 2013
In this study, we examined the impact of concurrent verbal and visuospatial working memory demands on performance of a visuospatial successive target detection task. Three hundred and four participants performed a visuospatial vigilance task while simultaneously performing either a spatial or verbal working memory task that either required a memory ...
McIntyre Peter B - - 2012
Three bacteria-Haemophilus influenzae, Streptococcus pneumoniae, and Neisseria meningitidis-account for most acute bacterial meningitis. Measurement of the effect of protein-polysaccharide conjugate vaccines is most reliable for H influenzae meningitis because one serotype and one age group account for more than 90% of cases and the incidence has been best measured in ...
Dzintars Eric - - 2012
Currently, a software-based second check dose calculation for helical tomotherapy (HT) is not available. The goal of this study is to evaluate the dose calculation accuracy of the in-house software using EGS4/MCSIM Monte Carlo environment against the treatment planning system calculations. In-house software was used to convert HT treatment plan ...
Oelschlaegel Stefanie - - 2012
Cornflower (Centaurea cyanus) honey can be characterized by a greenish-yellow color and an intensive flavor with a bitter aftertaste. Since cornflower honey contains only a limited amount of pollen for the verification of its floral origin, one objective was the characterization of its polyphenol and norisoprenoid content to assign floral ...
Zappitelli Michael - - 2012
Early acute kidney injury (AKI) diagnosis in critically ill children has been an important recent research focus because of the known association of AKI with poor outcomes and the requirement of early intervention to mitigate negative effects of AKI. In children having surgery, the preoperative period offers a unique opportunity ...
Clifford Tessen - - 2012
Twenty mothers participated in an online support group for parents of children with autism spectrum disorders. Twenty-five unrelated parents participated in a no-treatment control group. The participants completed online questionnaires prior to and following the 4-month support group, to evaluate changes in mood, anxiety, parenting stress, and positive perceptions. No ...
Kihm Hagyong - - 2012
A new mirror mounting technique applicable to the primary mirror in a space telescope is presented. This mounting technique replaces conventional bipod flexures with flexures having mechanical shims so that adjustments can be made to counter the effects of gravitational distortion of the mirror surface while being tested in the ...
Tummaruk Padet - - 2012
The aim of the present study was to investigate the effects of farrowing duration, parity number, and type of anti-inflammatory drug used postpartum on the incidence of postparturient disorders in sows. The duration of farrowing and postparturient disorders were examined in 64 sows at Days 0, 1, 2, and 3 after ...
Jang An Soo - - 2012
BACKGROUND: Refractory asthma, a subtype of asthma with uncontrolled symptoms despite antiasthma medications, is a heterogeneous syndrome with variable clinical features, presumably different etiologies, and pathophysiological mechanisms. The heterogeneity of refractory asthma, however, is poorly understood. We aimed to characterize refractory asthma and to improve our understanding of the heterogeneity ...
Mangino Massimo - - 2012
Twins have fascinated human communities since the beginning of recorded history. In cardiovascular research, twin studies played a pivotal role in the discovery of the genetic basis of coronary artery disease, myocardial infarction and most of their associated risk factors. Matched for age, prenatal and postnatal environmental factors, discordant monozygous ...
Koivistoinen A - - 2012
AIM: To identify linear peptide homing to non-small cell lung cancer (NSCLC) tumor cells using ex vivo phage display method. MATERIALS AND METHODS: Twenty-six clinical patient samples were used to identify linear homing peptide, which was exposed to NSCLC cell cultures and control cell lines to determine cell binding affinity ...
Meckel Stephan - - 2012
INTRODUCTION: 4D phase contrast MR imaging (4D PC MRI) has been introduced for spatiotemporal evaluation of intracranial hemodynamics in various cerebrovascular diseases. However, it still lacks validation with standards of reference. Our goal was to compare blood flow quantification derived from 4D PC MRI with transcranial ultrasound and 2D PC ...
Sadahiro Sotaro - - 2012
The most common site of metastases in patients with colorectal cancer is the liver. Hepatic resection is considered to be the treatment of choice for liver metastasis from colorectal cancer; however, hepatic resection can be performed in only 20 or 25 % of all patients. Recurrence develops in the remnant liver ...
Zhu Lei - - 2012
The influence of symmetry breaking in a planar metamaterial on transparency effect is numerically investigated. The planar metamaterial's cell is formed by three parallel metal wires. From numerical simulation results, we can see that the transparency effect results from the asymmetric coupling between the cut wires. The excited mechanism of ...
Dikken Johan L JL Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York, NY, - - 2013
Survival estimates after curative surgery for gastric cancer are based on AJCC staging, or on more accurate multivariable nomograms. However, the risk of dying of gastric cancer is not constant over time, with most deaths occurring in the first 2 years after resection. Therefore, the prognosis for a patient who ...
Lin Wenfang - - 2012
Microorganism in drinking water distribution system may colonize in biofilms. Bacterial 16S rRNA gene diversities were analyzed in both water and biofilms grown on taps with three different materials (polyvinyl chloride (PVC), stainless steel, and cast iron) from a local drinking water distribution system. In total, five clone libraries (440 ...
Tsutsumi Satoshi - - 2012
PURPOSE: This study aims to investigate the distribution and anatomic features of venous lacuna presenting with unusual upward protrusion (VLUUP) using high-resolution magnetic resonance (MR) imaging. METHODS: This retrospective study included 59 consecutive outpatients who underwent MR imaging with gadolinium. Acquired imaging data were transferred to a workstation for analysis. ...
Gu Haidong - - 2012
Brillouin frequency shift (BFS) in a single-mode optical fiber has been measured as a function of both radial and axial strain via the Brillouin optical time domain analysis technique. The effects of the two kinds of strain on the BFS are decoupled by making fiber pretensioned and relaxed while applying ...
Vlahović Milena - - 2012
Heavy metals damage the structure, chemistry, and function of cells, including enzyme systems inside them. Variation in the profile of biochemical biomarkers in prevalent species should be used for assessing environmental contamination. The present study pays attention to the phosphatases present in the midgut of gypsy moth fourth instar caterpillars, ...
Gupta Subash C - - 2013
Extensive research over the past half century has shown that curcumin (diferuloylmethane), a component of the golden spice turmeric (Curcuma longa), can modulate multiple cell signaling pathways. Extensive clinical trials over the past quarter century have addressed the pharmacokinetics, safety, and efficacy of this nutraceutical against numerous diseases in humans. ...
Kyriazis Iason - - 2012
PURPOSE: To evaluate the effect of vardenafil on renal function after renal ischemia-reperfusion (IR) injury (IRI) in a rat model. MATERIALS AND METHODS: Seventy-one Wistar rats were divided into 7 groups including (1) a vehicle-treated group, (2) a vehicle pretreated-IR group, (3-6) vardenafil pretreated-IR groups in doses of 0.02, 0.2, ...
Chandra Nagasuma - - 2013
Advances in genomics technologies are providing a very large amount of data on genome-wide gene expression profiles, protein molecules and their interactions with other macromolecules and metabolites. Molecular interaction networks provide a useful way to capture this complex data and comprehend it. Networks are beginning to be used in drug ...
Bacaër Nicolas - - 2012
For a certain class of multi-type branching processes in a continuous-time periodic environment, we show that the extinction probability is equal to (resp. less than) 1 if the basic reproduction number [Formula: see text] is less than (resp. bigger than) 1. The proof uses results concerning the asymptotic behavior of cooperative systems ...
Liang Xu - - 2012
AIM: This study was designed to explore the genetic polymorphism of IL-10 (-1082A/G, -592A/C, -819T/C), TNF-α (-308G/A) with susceptibility to docetaxel-induced liver injury (DILI) in Chinese breast cancer patients. METHODS: The targeted genetic polymorphisms of IL10-1082G/A, IL10-592A/C, IL10-819T/C, TNF-308G/A from 40 patients with DILI were assayed by matrix-assisted laser desorption/ionization-time ...
Takesue Yoshio - - 2012
To investigate the trends of antimicrobial resistance in pathogens isolated from surgical site infections (SSI), a Japanese surveillance committee conducted the first nationwide survey. Seven main organisms were collected from SSI at 27 medical centers in 2010 and were shipped to a central laboratory for antimicrobial susceptibility testing. A total ...
Hao Wei-Hua - - 2013
The chemotherapy agent gemcitabine is currently administered intravenously because the drug has poor oral bioavailability. In order to assess the pharmacokinetics and antitumor activity of D07001-F4, a new self-microemulsifying oral drug delivery system preparation of gemcitabine, this study was performed to compare the effect of D07001-F4 with administered gemcitabine in ...
Chen Shengli - - 2012
This paper describes the complete genome sequence of HX01, an isolate of the Newcastle disease virus (NDV) collected from a swine disease outbreak. The genome is 15,186 nt long and consists of six genes in the order of 3'-NP-P-M-F-HN-L-5'. This genome has the same length as the old NDV genotypes (I-IV), ...
Gozdowska Magdalena - - 2012
In this study, for the first time, both neuropeptides isotocin (IT) and arginine vasotocin (AVT) have been identified and measured in urophysis, the neurohaemal organ of the caudal neurosecretory system of teleost fish. So far, AVT, but not IT, was quantified by radioimmunoassay (RIA) in urophysis of several fish species. ...
Fargen Kyle M - - 2012
INTRODUCTION: Outcome after stroke intervention remains disappointing, with only 30-50% of patients having a good outcome at 90 days. We sought to identify important outcome prognosticators. METHODS: All consecutive patients that presented with an acute anterior circulation ischemic stroke, with adequate CT perfusion imaging, and that underwent emergency endovascular treatment ...
Haghighat Gholamhossein - - 2012
We investigate theoretically the effect of two-dimensional photonic crystal (PC) defect waveguide parameters embedded into vertical-cavity surface-emitting lasers (VCSELs) on static operation of PC-VCSEL, including spatial hole burning (SHB) and temperature in the active regions. In structures with larger pitch of PC holes, SHB occurs dramatically and temperature increases in ...
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