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Omar Rohani R Dementia Research Centre, UCL Institute of Neurology, London WC1N 3BG, - - 2013
Deficits of flavour processing may be clinically important in frontotemporal lobar degeneration (FTLD). To examine flavour processing in FTLD. We studied flavour identification prospectively in 25 patients with FTLD (12 with behavioural variant frontotemporal dementia (bvFTD), eight with semantic variant primary progressive aphasia (svPPA), five with non-fluent variant primary progressive ...
Haq Ihsan-Ul- - - 2012
Context: Natural products are a very productive source of leads for the development of medicines. Six Pakistani plants were chosen for study based on ethnobotanical data. Objective: Exploration of important medicinal plants of Pakistan for cancer treatment. Materials and methods: The crude extracts of the six plants and their fractions ...
Ferreira Paulo H - - 2012
BACKGROUND: The impact of the relationship (therapeutic alliance) between patients and physical therapists on treatment outcome in the rehabilitation of chronic low back pain (LBP) has not been previously investigated. OBJECTIVE: To investigate whether the therapeutic alliance between physical therapists and chronic LBP patients predicts clinical outcomes. DESIGN: Retrospective observational ...
Loy Douglas A - - 2012
Due to the bicontinuous phase structure of Nafion® with small hydrophilic channels, formation of composites with silica colloids to improve thermal stability, hydration and proton conductivity should be influenced by size and surface functionality of the colloids. To test this hypothesis we prepared batches of silica particles between 20 - ...
Zheng Jun - - 2012
Controlled chain-scission of polybutadiene (PB), polyisoprene, and poly(styrene-co-butadiene), induced by bis(cyclopentadienyl) zirconium hydrochloride (Cp(2) ZrHCl), was revealed at room temperature. The chain-scission reaction of linear PB was studied by means of GPC, NMR spectroscopy, and MALDI-TOF-MS. It was confirmed that the molecular weights of degraded products were quasi-quantitatively controlled by ...
Bram Anthony D - - 2012
Psychologists invest considerable time and labor in psychological testing and report writing. Patients and families expose vulnerabilities and make a significant financial and time investment in the hope that testing will make a difference in treatment. Frequently, though, handling of treatment implications in reports is generic, which might not justify ...
You Lijun - - 2012
The antioxidant and anti-fatigue activities of two peptides of <5 kD were determined, i.e., loach peptide A (LPA, from a papain digestion) and loach peptide B (LPB, from a flavorenzyme digestion). Their degrees of hydrolysis were 21±0.21% and 35±0.32%, respectively. LPA fraction mainly possessed peptides of 1000<MW<3000 Da (65.41%), while ...
Mercier Patrick P PP Microsystem Technology Laboratories, Massachusetts Institute of Technology, Cambridge, Massachusetts, - - 2012
Endocochlear potential (EP) is a battery-like electrochemical gradient found in and actively maintained by the inner ear. Here we demonstrate that the mammalian EP can be used as a power source for electronic devices. We achieved this by designing an anatomically sized, ultra-low quiescent-power energy harvester chip integrated with a ...
Dacey Marie - - 2012
Background: There is a need for effective continuing medical education (CME) programs to increase healthcare providers' knowledge and skills in lifestyle medicine so that healthcare providers are better equipped to assist patients in adopting and maintaining healthier lifestyle behaviors. Aims: To evaluate the impact of five live face-to-face CME programs ...
Ko Jooyeon - - 2012
BACKGROUND: The "Gross Motor Function Measure" (GMFM-88) is a commonly used measure for evaluating gross motor function in children with cerebral palsy (CP). The relative reliability of GMFM-88 has been assessed in children with CP. However, little information is available about the absolute reliability or responsiveness of GMFM-88. OBJECTIVE: The ...
Heimbach J K - - 2012
Obesity is increasingly common before and after liver transplantation (LT), yet optimal management remains unclear. Our aim was to analyze the effectiveness of a multidisciplinary protocol for obese patients requiring LT, including a noninvasive pretransplant weight loss program, and a combined LT plus sleeve gastrectomy (SG) for obese patients who ...
Wissgott C - - 2012
AIM:The study objective was to examine the application of excimer laser atherectomy (ELA) in patients with refractory occlusions in femoropopliteal arteries, where the initial conventional percutaneous transluminal angioplasty (PTA) recanalization attempts, were unsuccessful. METHODS: The average age of the 40 patients (32 men, 8 women) included in this study was ...
Everitt Hannah H Department of Molecular Pharmacology, University of South Florida Health Sciences Center, Tampa, FL 33612, - - 2013
Alcohol consumption synergistically increases the risk and severity of liver damage in obese patients. To gain insight into cellular or molecular mechanisms underlying the development of fatty liver caused by ethanol-obesity synergism, we have carried out animal experiments that examine the effects of ethanol administration in genetically obese mice. Lean ...
Roth Christian - - 2012
BACKGROUND AND PURPOSE: The aim of our study was to examine surgical practice in the therapy of spontaneous intracerebral hemorrhage in Germany over a period of 10 years. METHODS: In 1999 and 2009 a questionnaire with 10 different cases of spontaneous intracerebral hemorrhage was sent to all neurosurgical centers in ...
Echegoyen Carlos - - 2012
Abstract Understanding the relationship between a search algorithm and the space of problems is a fundamental issue in the optimization field. In this paper, we lay the foundations to elaborate taxonomies of problems under estimation of distribution algorithms (EDAs). By using an infinite population model and assuming that the selection ...
Hayes Don D - - 2012
We present a patient that is the index case of pulmonary arterial hypertension (PAH) in a child due to the bone morphogenetic protein type II (BMPR2) missense mutation p.K230N, also known as c.690A>T. Missense mutations typically have earlier onset and more severe disease in PAH, so pulmonologists should be aware ...
Molt Robert W - - 2012
We have identified the major conformers of CL-20 explosive, otherwise known as 2,4,6,8,10,12- hexanitrohexaazaisowurtzitane, more formally known as 2,4,6,8,10,12-hexanitrohexaazatetracyclo [5.5.0.0]-dodecane, via Monte-Carlo search in conformational space through molecular mechanics and subsequent quantum mechanical refinement using perturbation theory. Our search produced enough conformers to account for all of the various forms ...
Murdoch Barbara - - 2012
Lifelong neurogenesis in the mouse olfactory epithelium (OE) is regulated by the response of stem/progenitor cells to local signals, but embryonic and adult OE progenitors appear to be quite different - with potentially different mechanisms of regulation. A recently identified progenitor unique to embryonic OE - the nestin+ radial glia-like ...
Hu Zejun - - 2012
A thorough understanding of the genetic basis of rice grain traits is critical for the improvement of rice varieties. In this study, we generated an F(2) population by crossing the large-grain japonica cultivar CW23 with Peiai 64 (PA64), an elite indica small-grain cultivar. Using QTL analysis, 17 QTLs for five ...
Rossi Giulia - - 2012
Non-ionic surfactants are used for the isolation and purification of membrane proteins, as well as for the study of fundamental aspects of protein diffusion in membranes. Here we present a new coarse-grained model of polyethylene glycol (PEG) and of the family of polyoxyethylene alkyl ether (CiEj) surfactants. The model is ...
Cutolo Carlo A - - 2012
Purpose. Dupuytren disease is an inherited proliferative and progressive connective disease. Ectopic disease may, however, be located distant from the palmar fascia. 
Methods. Case report and review of the literature. 
Results. We describe a case of symmetric bilateral posterior subcapsular cataracts associated with symmetric bilateral Dupuytren disease and symmetric bilateral ...
Treacy Ann Deborah - - 2012
Abstract OBJECTIVE: Placental villous maturation is maximal in the third trimester with an abundance of terminal villi. Delayed villous maturation (DVM) of the placenta is associated with chromosomal abnormalities, gestational diabetes and an adverse outcome. The aim of this study was to compare quantitative assessment of vasculo-syncytial membranes in cases ...
Heckenkamp J - - 2012
We describe the feasibility and result of a novel approach to preserve pelvic perfusion during endovascular aortoiliac aneurysm repair (EVAR) in patients with aortoiliac aneurysms extending to the iliac bifurcation. The iliac chimney-graft technique consists of the deployment of a ViaBahn™ graft into the hypogastric artery in combination with standard ...
Yardley Jane E - - 2012
Abstract Background: Previous studies of aerobic exercise have found lower sensor accuracy during exercise. Whether or not resistance exercise would also be associated with lower sensor accuracy has not yet been examined. This study sought to investigate the accuracy of continuous glucose monitoring sensor values at rest, during aerobic exercise, ...
Briand François - - 2012
OBJECTIVE: This study aimed to investigate whether cholesteryl ester transfer protein inhibition promotes in vivo reverse cholesterol transport in dyslipidemic hamsters. METHODS AND RESULTS: In vivo reverse cholesterol transport was measured after an intravenous injection of (3)H-cholesteryl-oleate-labeled/oxidized LDL particles ((3)H-oxLDL), which are rapidly cleared from plasma by liver-resident macrophages for ...
Priebe Gisela - - 2012
This study investigated three dimensions of sexual orientation-identity, attraction, and behavior-in a national survey of late adolescents. Prevalence rates and the diversity of dimensions of sexual orientation when combined were studied. A representative sample of 3,432 Swedish high school seniors completed an anonymous school-based self-report survey about sexuality, Internet use, ...
McCleland Mark L - - 2012
Breast cancer has been redefined into three clinically relevant subclasses: (i) estrogen/progesterone receptor positive (ER+/PR+), (ii) HER2/ERRB2 positive, and (iii) those lacking expression of all three markers (triple negative or basal-like). While targeted therapies for ER+/PR+ and HER2+ tumors have revolutionized patient treatment and increased lifespan, an urgent need exists ...
Yoo Dongwon D Department of Chemistry, Yonsei University, Seoul 120-749, - - 2012
Highly efficient apoptotic hyperthermia is achieved using a double-effector nanoparticle that can generate reactive oxygen species (ROS) and heat. ROS render cancer cells more susceptible to subsequent heat treatment, which remarkably increases the degree of apoptotic cell death. Xenograft tumors (100 mm(3)) in mice are completely eliminated within 8 days after a ...
Lucarelli R T - - 2012
BACKGROUND AND PURPOSE:Asymmetry of the hippocampus is regarded as an important clinical finding, but limited data on hippocampal asymmetry are available for the general population. Here we present hippocampal asymmetry data from the Dallas Heart Study determined by automated methods and its relationship to age, sex, and ethnicity.MATERIALS AND METHODS:3D ...
Cha Chaenyung C Center for Biomedical Engineering, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Cambridge, Massachusetts 02139, United - - 2012
As stem cells are a cornerstone of regenerative medicine, research efforts have been extensively focused on controlling their self-renewal and differentiation. It is well-known that stem cells are tightly regulated by a combination of physical and chemical factors from their complex extracellular surroundings; thus, conventional cell culture approaches based purely ...
Khaladj Nawid N Department of Cardiac, Thoracic, Transplantation and Vascular Surgery, Hannover Medical School, Hannover, Germany. - - 2013
The management of infected Dacron grafts in the ascending aortic position involving the aortic arch and aortic root remains a technical challenge. Total replacement of the infected graft material with cryopreserved homografts appears to be an effective treatment strategy for these patients. Seventeen consecutive patients were operated on for infection ...
Perone Sammy S Department of Psychology and Delta Center, University of Iowa, Iowa City, IA 52242, USA. - - 2013
Looking is a fundamental exploratory behavior by which infants acquire knowledge about the world. In theories of infant habituation, however, looking as an exploratory behavior has been deemphasized relative to the reliable nature with which looking indexes active cognitive processing. We present a new theory that connects looking to the ...
Hari Yoshiyuki - - 2012
Oligonucleotides containing 4'-carboxy-, 4'-methoxycarbonyl-, 4'-carbamoyl-, and 4'-methylcarbamoyl-thymidines, and their 2'-methoxy, 2'-amino or 2'-acetamido analogs were prepared. Their duplex-forming ability with DNA and RNA complements was evaluated by UV melting experiments. Interestingly, 4'-carboxythymidine existing in the S-type sugar conformation was found to lead to an increase in the stability of the ...
Dai Xiaoqian - - 2012
Quercetin, existing mostly in its glycoside form quercitrin, is the most widely distributed flavonoid in nature. It possesses various potential effects as an antioxidant, anti-inflammatory for cell damage of β-cells, however, studies on this topic are limited and controversial. In order to examine the effects of quercetin on type I diabetes ...
Eghbalsaied Shahin - - 2012
Transgenic mammals have been produced by using sperm as vector for exogenous DNA (sperm-mediated gene transfer or SMGT) in combination with artificial insemination (AI). Our study evaluated if SMGT could also be achieved in combination with in vitro fertilisation (IVF) to efficiently produce transgenic bovine embryos. We assessed binding and ...
Rudzinski Erin R - - 2012
Abstract Chronic villitis of unknown etiology (VUE) occurs in approximately 5-10% of third trimester placentas. It is characterized by lymphohistiocytic infiltration of the placental chorionic villi. VUE is associated with fetal growth restriction, preterm birth, and recurrent pregnancy loss. Accumulating evidence suggests that VUE may represent a host-versus-graft reaction, analogous ...
Suter Melissa A MA Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, Baylor College of Medicine, 1 Baylor Plaza, Jones 314, Houston, TX 77030, - - 2013
Although the association between maternal smoking and low birthweight infants has been well established, the mechanisms behind reduced fetal growth are still being elucidated. While many infants are exposed to tobacco smoke in utero, not all are born growth restricted or small for gestational age. Many hypotheses have emerged to ...
Bekhet Abir K - - 2012
Background: Approximately 2.8 million people in the United States are diagnosed with autism spectrum disorder (ASD). Family caregivers manage many aspects of their care, which is demanding, overwhelming, and can affect their mental health. Objective: This study examined the effects of caregiver burden (risk factor) and positive cognitions (protective factors) ...
Boon James J Biology of Lipid Metabolism Laboratory, Department of Physiology, Monash University, Clayton, Victoria, - - 2013
Dysregulated lipid metabolism and inflammation are linked to the development of insulin resistance in obesity, and the intracellular accumulation of the sphingolipid ceramide has been implicated in these processes. Here, we explored the role of circulating ceramide on the pathogenesis of insulin resistance. Ceramide transported in LDL is elevated in ...
Mackintosh L J - - 2012
Background:  Organ transplant recipients have an increased risk of skin cancers. A specialist dermatology clinic for renal transplant recipients (RTRs) was established in 2005. Objectives:  To analyse the type and incidence of skin cancers in prevalent patients attending after renal transplant in the West of Scotland and analyse the impact ...
Vuong Cuong D - - 2012
Please cite this paper as: Vuong et al. (2012). The genetic match between vaccine strains and circulating seasonal influenza A viruses in Vietnam, 2001-2009. Influenza and Other Respiratory Viruses DOI: 10.1111/irv.12038. Background  Vietnam is currently developing domestic capability to manufacture influenza vaccines but information on the genetic and antigenic characteristics of ...
Iribarren Carlos - - 2012
Asthma has been associated with increased cardiovascular disease (CVD) risk. The authors ascertained the association of asthma with CVD and the roles that sex, concurrent allergy, and asthma medications may play in this association. They assembled a cohort of 203,595 Northern California adults with asthma and a parallel asthma-free referent ...
Malhotra Pooja P Section of Digestive Diseases and Nutrition, Department of Medicine, University of Illinois at Chicago, and Jesse Brown VA Medical Center, Chicago, Illinois 60612, - - 2013
The expression of intestinal Niemann-Pick C1-like 1 (NPC1L1) cholesterol transporter has been shown to be elevated in patients with diseases associated with hypercholesterolemia such as diabetes mellitus. High levels of glucose were shown to directly increase the expression of NPC1L1 in intestinal epithelial cells, but the underlying mechanisms are not ...
Bannani Fatma - - 2012
The high-nuclearity polyoxothiomolybdate [H8Mo84S48O188(H2O)12(CH3COO)24]32- has been prepared and characterized by single-crystal X-ray crystallography and spectroscopically (1H NMR, IR and Raman, UV-vis). The solid-state structure reveals an unprecedented and intriguing arrangement comprising a nanoscaled anionic cube. The surprisingly open structure of this {Mo84}-type cubic box features a large inner void, accessible ...
Cantarini Luca - - 2012
OBJECTIVES: Idiopathic recurrent acute pericarditis (IRAP) represents the most troublesome complication of acute pericarditis and is an autoimmune process. White adipose tissue produces more than 50 adipokines that participate in inflammation and autoimmunity. This study investigated whether serum leptin, resistin, visfatin and adiponectin are increased in IRAP versus healthy controls ...
Huh Jin Won - - 2012
BACKGROUND: The Surviving Sepsis Campaign (SSC) to improve patient outcomes in severe sepsis and septic shock contains recommendations for protocolised resuscitation including early goal-directed therapy (EGDT) resuscitation. In EGDT, central venous oxygen saturation (ScvO(2)) is measured as the target monitoring value. The objective of this study was to determine whether ...
Sharifi Roya - - 2012
Context: Silymarin, a flavonolignan from Silybum marianum (L.) Gaertn. (Asteraceae), has been reported to have antioxidant and anti-inflammatory properties. Therefore, it may be worthwhile to study the effect of silymarin on wound healing. Objective: To evaluate the effect of silymarin on human fibroblast cells in an in vitro model of ...
Paxton Christian N - - 2012
OBJECTIVE: Chromosome analysis is the traditional method for detecting genetic abnormalities in products of conception, but it is prone to a high failure rate because of the requirement for cell culture. Molecular genetic tests do not require cell culture, but are either more expensive (e.g. chromosomal microarray) or less sensitive ...
Bonales Laura J - - 2012
In this work, we study how structures develop on 2D dense binary colloidal monolayers as a function of the relative concentration of small/large particles. Translational and orientational distribution functions have been used to monitor the continuous phase transition through a detailed characterization of the global and local order. We have ...
Muhtz Christoph - - 2012
OBJECTIVE.: Chronic pain and major depression have been associated with alterations of the hypothalamus-pituitary-adrenal axis (HPA) activity. Previous studies suggested that HPA activity is diminished in chronic pain but increased in depression. However, little is known about the effects of experimentally induced acute pain on cortisol secretion in patients with ...
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