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Seder-Colomina M - - 2012
Microbial mats are coastal ecosystems that consist mainly of cyanobacteria, primary producers in these habitats that play an important role in stabilising delta sediments. However, these ecosystems are subject to various kinds of pollution, including metal contamination, placing their survival at risk. Among heavy metals, copper is an essential metal ...
Gordon Sarah - - 2012
The potential of UV imaging as a new small scale flow-through dissolution testing platform and its ability to incorporate biorelevant media was tested. Furosemide was utilized as a model poorly soluble drug, and dissolution media simulating conditions in the small intestine (5/1.25 mM and 40/10 mM bile salt/phospholipid, pH 6.5) together with ...
Malheiro V N - - 2012
The use of a porous coating on prosthetic components to encourage bone ingrowth is an important way of improving uncemented implant fixation. Enhanced fixation may be achieved by the use of porous magneto-active layers on the surface of prosthetic implants, which would deform elastically on application of a magnetic field, ...
Bergenstal Richard M - - 2012
The efficacy and safety of taspoglutide, a long-acting human glucagon-like peptide-1 analog, were compared with sitagliptin or placebo, as adjunct to metformin, in patients with inadequately controlled type 2 diabetes. In this randomized, double-blind, double-dummy, parallel-group trial, patients were randomized to taspoglutide 10 mg once weekly (QW), 20 mg QW, 100 mg sitagliptin ...
Liu Yizhu - - 2012
Ethynyl-linked porphyrin hetero-dimers substituted by a series of electron donors, namely, bis(4-methoxyphenyl)amino (), bis(4-tert-butylphenyl)amino () and 3,6-di-tert-butylcarbazol-9-yl () as well as a reference dimer with a non-donor moiety (3,5-di-tert-butylphenyl, ) have been synthesized to systematically investigate the influence of donor introduction on the photovoltaic performances of near-IR dye-sensitized solar cells ...
Beck Philipp - - 2012
We have studied the dependence of metal oxide properties in molecular dynamics (MD) simulations on the polarizability of oxygen ions. We present studies of both liquid and crystalline structures of silica (SiO(2)), magnesia (MgO) and alumina (Al(2)O(3)). For each of the three oxides, two separately optimized sets of force fields ...
Fairfax Keke - - 2012
Schistosomiasis is caused by infection with parasitic flatworms of the genus Schistosoma. It is characterized by the development of strong CD4(+) T cell and B cell responses that, during primary infection, fail to eliminate the parasites, but in collaboration with cells of the innate immune system allow survival in the ...
Van Der Vorst H - - 2012
AIMS: The aim of the current study was to examine the mediating role of alcohol-related memory associations in the relation between perceived parental drinking and the onset of adolescents' alcohol use. Gender and grade were also included in the analyses. DESIGN: We tested a mediation model within a structural path ...
Boyle Kelly S - - 2012
Sound production that is mediated by intrinsic or extrinsic swim bladder musculature has evolved multiple times in teleost fishes. Sonic muscles must contract rapidly and synchronously to compress the gas-filled bladder with sufficient velocity to produce sound. Muscle modifications that may promote rapid contraction include small fiber diameter, elaborate sarcoplasmic ...
Lopez-Jornet Pia - - 2012
Tissue repair is a complex process, which may be favoured or inhibited by different factors. Potassium apigenin (AP) and other flavonoids present in verbena extract (PLX®) possess powerful anti-inflammatory properties. The aim of this study was to evaluate the effects of topical treatment with AP and PLX gels on wounds ...
Wachsmuth N B - - 2012
Aim of the study was to determine the influence of classic altitude training on hemoglobin mass (Hb-mass) in elite swimmers under the following aspects: (1) normal oscillation of Hb-mass at sea level; (2) time course of adaptation and de-adaptation; (3) sex influences; (4) influences of illness and injury; (5) interaction ...
Uebelacker L A - - 2012
BACKGROUND: Anxiety disorders are very common and increase risk for suicide attempts. Little is known about predictors of increased risk specifically among individuals with anxiety disorders. The purpose of this study was to investigate whether specific anxiety disorders and other co-morbid psychiatric disorders, physical health, or work or social functioning ...
Bakheit Abdel Magid O - - 2012
Muscle hypertonia following upper motor neurone lesions (referred to here as 'spasticity') is a common problem in patients with neurological disease, and its management is one of the major challenges in clinical practice. Understanding the pathogenesis and clinical course of spasticity is essential for the effective management of this condition. ...
Okubo Akiko - - 2012
PURPOSE: To report findings of optic disc melanocytoma (ODM) obtained using spectral domain optical coherence tomography (SD OCT), with special reference to the central retinal artery and vein surrounded by hyperreflective dots. METHODS: Retrospective review of five eyes of five patients with ODM. Demographic information, ophthalmic examination including best-corrected visual ...
Serpell Christopher J - - 2012
The synthesis and characterisation of a series of new gold- and palladium-containing symmetrical imidazolium salts are described which display significant cation-dependent effects determined by the structure of the alkyl chains of the imidazolium motifs. Whereas direct reduction of the Pd salts can produce stable nanoparticles (NPs) coated by imidazolium salts, ...
Zhang Zhe - - 2012
Mussels have been shown to attach to virtually all types of inorganic and organic surfaces via their adhesive proteins. The adhesive proteins secreted by mussels contain high concentrations of catechol and amine functional groups, which have similar functional groups with polydopamine (PDA). Inspired by mussels, a mild and environmentally friendly ...
Kastler Adrian - - 2012
OBJECTIVE: To describe and evaluate the feasibility and efficacy of CT-guided radiofrequency neurolysis (RFN) vs. local blockade of the stellate ganglion in the management of chronic refractory type I complex regional pain syndrome (CRPS) of the upper limb. METHODS: Sixty-seven patients were included in this retrospective study between 2000 and ...
Bert Pierre-François - - 2012
Iron is essential to plants for chlorophyll formation as well as for the functioning of various iron-containing enzymes. Iron deficiency chlorosis is a wide-spread disorder of plants, in particular, of those growing on calcareous soils. Among the different ways to control iron deficiency problems for crops, plant material and especially ...
Orhan Hilmi - - 2012
Objective: To investigate whether lipid and protein oxidation products are elevated and correlated with routine clinical markers of hepatic and renal function in patients anesthetized with halothane, isoflurane, or sevoflurane. Methods: Urine and blood samples were collected from patient groups. Excretion of aldehydes, acetone, and o,o'-dityrosine was measured before and ...
Chang Minwook - - 2012
BACKGROUND: The aim of this study was to evaluate the long-term outcomes after unilateral orbital fat decompression in patients with thyroid eye disease. DESIGN: Retrospective, comparative, cross-sectional study PARTICIPANTS: Thirty-three orbits of 33 patients were included in this study. Of the 33 patients, 13 underwent fat decompression (group A), and ...
Bohnstedt C - - 2012
Children with Down syndrome (DS) and acute lymphoblastic leukemia (ALL) have an inferior prognosis compared to non-DS ALL patients. We reviewed Methotrexate (MTX)/Mercaptopurine (6MP) maintenance therapy data for children with DS treated according to the NOPHO ALL92 or the NOPHO ALL2000 protocols between 1992 and 2007. The five year event-free ...
Henderson M - - 2012
BACKGROUND: Long-term sickness absence (LTSA) is most commonly due to common mental disorders and symptom-based conditions. Relatively little research has examined individual, as opposed to occupational, risk factors for LTSA. Individual appraisal of the workplace has been considered in several studies but self-rated health has more often been examined as ...
Khot V M - - 2012
MgFe(2)O(4) nanoparticles with sizes around 20 nm have been prepared by a combustion method and functionalized with dextran for their possible applications in magnetic particle hyperthermia. The induction heating study of these nanoparticles at different magnetic field amplitudes, from 6.7 kA m(-1) to 26.7 kA m(-1), showed self-heating temperature rise ...
Kim S C - - 2012
We report on several new basic properties of a parabolic dot in the presence of a magnetic field. The ratio between the potential strength and the Landau level (LL) energy spacing serves as the coupling constant of this problem. In the weak coupling limit the energy spectrum in each Hilbert ...
Chevallier Coralie - - 2012
Diminished social attention is often considered to be a central deficit in autism spectrum disorders (ASDs). We further investigate this hypothesis by measuring the distracting power of social and non-social stimuli in the context of a Stroop task among children with ASD and typically developing controls (TDCs). Our results show ...
Ben-Hadj-Khalifa Sonia - - 2012
Background: Monocytes and factor Xa (FXa) are procoagulant agents implicated in the physio-pathological processes of atherosclerosis and thrombosis. Objective: we evaluated the anticoagulant effect of the anti-inflammatory cytokine IL-10 on an FXa-activated human monocyte (Hu-monocyte) procoagulant phenotype. Methods: Hu-monocytes were purified by elutriation and activated by FXa. The effect of ...
Hautzel Hubertus - - 2012
Background: When applying the recommended standard doses of recombinant human TSH (rhTSH) in the diagnostic / therapeutic course of patients with differentiated thyroid cancer (DTC) the resulting peak TSH levels vary extensively. Previous studies applying multivariate statistics identified patient-inherent variables influencing the rhTSH / peak TSH relation. However, those results ...
Yang Xinying - - 2012
ACTG-toxin H (AH) originates from Alternaria sp. In this study, we explored the molecular mechanism underlying the anti-inflammatory properties of AH. Treatment with AH inhibited lipopolysaccharide (LPS)-induced interleukin-6, IL-1β, inducible nitric oxide synthase, and cyclooxygenase-2 expression and nitric oxide production. Furthermore, AH inhibited LPS-induced P38 MAPK and Akt activation in ...
Sreedhara Alavattam - - 2012
The reduction of singlet oxygen to hydrogen peroxide via the antibody catalyzed water oxidation pathway (ACWOP) has been reported (Nieva and Wentworth, Trends in Biochem. Sci, 2004, 29, 274-278). While conserved and buried tryptophans in the antibody are thought to play a major role in this pathway, our studies with ...
Sajid M S - - 2012
OBJECTIVE: To systematically compare the tacker mesh fixation (TMF) with the suture mesh fixation (SMF) in laparoscopic incisional and ventral hernia (LIVH) repair. METHODS: Trials evaluating the TMF with the SMF in LIVH repair were analysed using the statistical tool RevMan(®). Combined dichotomous and continuous data were expressed as odds ...
González Santiago - - 2012
We propose that systems exhibiting compositional patterning at the nanoscale, so far assumed to be due to some kind of ordered phase segregation, can be understood instead in terms of coherent, single phase ordering of minority motifs, caused by some constrained drive for uniformity. The essential features of this type ...
Wiegand Thomas - - 2012
Frustrated Lewis pair (FLP) chemistry has provided a new strategy for small molecule binding and/or catalytic activation. It is based on the cooperative reaction behavior of Lewis acid and Lewis base centers that are in close proximity to each other (e.g., within the same molecule) but cannot form a direct ...
Green Joel A - - 2012
BACKGROUND: Brain tissue oxygen monitoring (pBtO2) has been advocated in the treatment of patients with severe traumatic brain injuries (TBI); however, controversy exists regarding the improvements that pBtO2 monitoring provides. The objective of our study was to evaluate our experience and effect on mortality with goal directed pBtO2 monitoring for ...
Angelo Isabele C - - 2012
The tick's fat body plays an essential role in energy storage and utilization. This study aimed to analyze the fat body neutral lipid composition in Rhipicephalus microplus engorged females. In the first study (physiological profile of untreated ticks), the lipid analysis took place over the course of 4 days; the engorged ...
Zadran Sohila - - 2012
Metabolic engineering seeks to redirect metabolic pathways through the modification of specific biochemical reactions or the introduction of new ones with the use of recombinant technology. Many of the chemicals synthesized via introduction of product-specific enzymes or the reconstruction of entire metabolic pathways into engineered hosts that can sustain production ...
Chai Bo - - 2012
Porous graphitic carbon nitride (g-C(3)N(4)) was prepared by a simple pyrolysis of urea, and then a g-C(3)N(4)-Pt-TiO(2) nanocomposite was fabricated via a facile chemical adsorption followed by a calcination process. The obtained products were characterized by X-ray diffraction, X-ray photoelectron spectroscopy, UV-vis diffuse reflectance absorption spectra, and electron microscopy. It ...
Chen Yun-Ru - - 2012
Dendritic cells (DCs) are professional antigen presenting cells that activate and modulate immune responses, but the mechanisms underlying DC activation have not been fully understood. In this study, we investigated the role of Notch signaling in DC activation by using murine bone marrow-derived DCs. Triggering of Toll-like receptors (TLRs) of ...
Haas J - - 2012
Current studies suggest dysfunctional emotional processing as a key factor in the aetiology of temporomandibular disorder (TMD). Investigating facial emotion recognition (FER) may offer an elegant and reliable way to study emotional processing in patients with TMD. Twenty patients with TMD and the same number of age-, sex- and education-matched ...
Ponnuswamy Nandhini - - 2012
Molecular knots remain difficult to produce using the current synthetic methods of chemistry because of their topological complexity. We report here the near-quantitative self-assembly of a trefoil knot from a naphthalenediimide-based aqueous disulfide dynamic combinatorial library. The formation of the knot appears to be driven by the hydrophobic effect and ...
Pananwala Hasitha - - 2012
BACKGROUND: Solitary necrotic nodule of the liver (SNNL) is a rare benign lesion with an uncertain aetiology. There are no typical diagnostic clinical or radiological features, and this lesion is usually detected incidentally during imaging for other purposes. METHODS: We describe the clinical and radiological findings in three patients with ...
Berger Gregory L - - 2012
Genome-wide association studies (GWAS) provide an opportunity to examine the genetic architecture of quantitatively inherited traits in breeding populations. The objectives of this study were to use GWAS to identify chromosome regions governing traits of importance in six-rowed winter barley (Hordeum vulgare L.) germplasm and to identify single-nucleotide polymorphisms (SNPs) ...
Sanguanmith Sunuchakan - - 2012
In the spirit of the radiation chemical "spur model", the lifetime of a spur (τ(s)) is an important indicator of overlapping spurs and the establishment of homogeneity in the distribution of reactive species created by the action of low linear energy transfer (LET) radiation (such as fast electrons or γ ...
Kothavade R J - - 2012
Rapidly growing mycobacteria (RGM) are known to cause pulmonary, extra-pulmonary, systemic/disseminated, and cutaneous and subcutaneous infections. The erroneous detection of RGM that is based solely on microscopy, solid and liquid cultures, Bactec systems, and species-specific polymerase chain reaction (PCR) may produce misleading results. Thus, inappropriate therapeutic measures may be used ...
Huo J - - 2012
Multiple myeloma (MM) is an incurable malignancy of terminally differentiated B lymphoid cells. Here, we investigated the role of Fas apoptosis inhibitory molecule (FAIM) in MM. We demonstrated that IGF-1 treatment up-regulated FAIM expression in MM cells in a dose-dependent manner. Silencing of FAIM expression attenuates Akt signaling downstream of ...
Goffman Lisa - - 2012
ABSTRACT The aim of this study was to determine, using speech error and articulatory analyses, whether the binary distinction between iambs and trochees should be extended to include additional prosodic subcategories. Adults, children who are normally developing, and children with specific language impairment (SLI) participated. Children with SLI were included ...
Voet Vincent S D - - 2012
The fabrication of nanoporous poly(vinylidene fluoride) (PVDF) and PVDF/nickel nanocomposites from semicrystalline block copolymer precursors is reported. Polystyrene-block-poly(vinylidene fluoride)-block-polystyrene (PS-b-PVDF-b-PS) is prepared through functional benzoyl peroxide initiated polymerization of VDF, followed by atom transfer radical polymerization (ATRP) of styrene. The crystallization of PVDF plays a dominant role in the formation ...
Zhang Ming-Zhen - - 2012
Quantum dots (QDs) fluorescent probes based on oligonucleotide aptamers and peptides with specific molecular recognition have attracted much attention. In this paper, CdSe/ZnS QDs probes for targeted delivery to mouse and human cells using aptamer GS24 and peptide T7 specific to mouse/human transferrin receptors were developed. Capillary electrophoresis analyses indicated ...
Eiamsa-Ard Pradinunt - - 2012
The lower plant Physcomitrella patens synthesizes several long-chain polyunsaturated fatty acids (LC-PUFAs) by a series of desaturation and elongation reactions. In the present study, the full-length cDNAs for two novel fatty acid elongases designated PpELO1 and PpELO2 were isolated from P. patens using a PCR-based cloning strategy. These cDNAs encoding ...
Schmier Jordana K - - 2012
BACKGROUND: Topical β-blockers are commonly prescribed for primary open-angle glaucoma. Existing research is limited regarding respiratory or cardiovascular events that may result from using these topical β-blockers. OBJECTIVE: To evaluate inpatient and outpatient service encounters and payments associated with the topical adjunctive use of the β-blocker timolol for glaucoma. STUDY ...
Du Peng - - 2012
Four novel metal-organic frameworks (MOFs) based on high-nuclear metal carboxylate clusters, namely, [Zn(4)(L)(2)(μ(3)-OH)(2)(H(2)O)(1.5)]·2H(2)O (), [Zn(5)Na(L)(2)(μ(3)-OH)(4)(CH(3)CH(2)O)(H(2)O)(2)] (), [Cd(4)(L)(2)(BIME)(0.5)(μ(3)-OH)(2)(H(2)O)(1.5)]·2H(2)O (), and [Zn(4)(L)(2)(BET)(0.5)(μ(3)-OH)(2)(H(2)O)] (), where H(3)L = (3,5-dicarboxyl-phenyl)-(4-(2'-carboxyl-phenyl)-benzyl)ether, BET = 1,1'-(2'-oxybis(ethane-2,1-diyl))bis(1,2,4-triazol-1-yl), BIME = 1,2-bis(imidazol-1-yl)ethane, have been synthesized under hydrothermal conditions. In , each planar octanuclear zinc cluster [Zn(8)(μ(3)-OH)(8)(CO(2))(12)(H(2)O)(3)] is linked by twelve L ...
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