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Results 301 - 350 of 2099
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Marcucci Daniel J - - 2012
Landscape-level green infrastructure creates a network of natural and semi-natural areas that protects and enhances ecosystem services, regenerative capacities, and ecological dynamism over long timeframes. It can also enhance quality of life and certain economic activity. Highways create a network for moving goods and services efficiently, enabling commerce, and improving ...
Orji Foster Tochukwu - - 2012
BACKGROUND: The frequent relapses of recurrent respiratory papillomatosis (RRP) sometimes demand repeated surgical excision with tracheostomy. This situation plays a vital role in the management of RRP in developing countries such as ours because of late presentation. This study was conducted to evaluate our experience with RRP and to determine ...
Wang Hui - - 2012
Glycoproteins derived from Hansenula polymorpha can not be used for therapeutic purposes due to their high-mannose type asparagine-linked (N-linked) glycans, which result in immune reactions and poor pharmacokinetic behaviors in human body. Previously, we reported that the trimannosyl core N-linked glycans (Man(3)GlcNAc(2)) intermediate can be generated in endoplasmic reticulum in ...
Vallianou Natalia G - - 2012
BACKGROUND: Neck circumference, beyond a measure of obesity, is a unique fat depot with increasing significance. This study aimed to investigate the association between neck circumference and biomarkers, indicators of cardiovascular risk. METHODS: During 2009, 490 volunteers (46 ± 16 years, 40% males) were consecutively enrolled to the study (participation rate 85%). Biochemical ...
Atashi Hadi - - 2012
In the present study, 1,635 lambing records of Ghezel (n = 766) and Mehraban (n = 869) breeds were used to evaluate the early growth traits, litter size, and lamb survival in sheep reared in Fars Province, southern Iran, during a 5-year-long period. The least squares means (± SE) of lamb birth weight for ...
Germain M - - 2012
Background and Objectives  In many jurisdictions, blood donors who have an atypical pulse rate are temporarily deferred. This practice is not supported by evidence. We evaluated whether accepting donors with an atypical pulse rate increases their risk of cardiac ischaemic events. Methods  We measured the cumulative incidence of hospitalizations and ...
Kluxen Felix M - - 2012
Cadmium (Cd) affects the expression of estrogen receptor (ER) and aryl hydrocarbon receptor (AhR)-associated genes in rat uterus and elicits estrogen-like activity in vitro. The small intestine is highly exposed to dietary Cd which may mimic or antagonize estrogen action in this tissue. We investigated the effects of Cd and ...
Cozzi Denis Andrew - - 2012
BACKGROUND: Evidence-based guidelines for the management of localized perinatal adrenal neuroblastoma are not yet available. We describe our preliminary experience managing this tumor with a "wait and see" policy. METHODS: A single-center prospective study (February 2002 to December 2009) was conducted with 12 consecutive patients in whom an adrenal mass ...
Lafrentz B R - - 2012
Flavobacterium columnare is a Gram-negative bacterium that causes columnaris disease and has significant economic impacts on aquaculture production worldwide. Molecular analyses have demonstrated that there is genetic diversity among F. columnare isolates. A review of the published literature that used restriction fragment length polymorphism analysis of the 16S rRNA gene ...
Ma Lijun - - 2012
Spinal cord biologically effective dose (BED) limits are critical to safe spine stereotactic body radiotherapy (SBRT) delivery. In particular, when repeating SBRT to the same site, the problem of adding non-uniform BED distributions within small volumes of spinal cord has yet to be solved. We report a probability-based generalized BED ...
Zhu Xiao - - 2012
It has been hypothesized that adipocytokines originating from adipose tissue may have an important role in bone metabolism. Vaspin is a novel adipocytokine isolated from visceral white adipose tissue, which has been reported to have anti-apoptotic effects in vascular endothelial cells. However, to the best of our knowledge there is ...
Nightingale Adrian M - - 2012
In the past decade microreactors have emerged as a compelling technology for the highly controlled synthesis of colloidal nanocrystals, offering multiple advantages over conventional batch synthesis methods (including improved levels of control, reproducibility, and automation). Initial work in the field employed simple continuous phase reactors that manipulate miscible streams of ...
Vegh T - - 2012
BACKGROUND: The ideal tidal volume (VT) during one-lung ventilation (OLV) remains controversial. High tidal volumes may increase the incidence of postoperative lung injury after thoracic surgery. There is nonetheless little evidence that the use of low tidal volume during OLV will fail to provide adequate arterial oxygenation. We evaluated the ...
MacLean Katherine A KA Behavioral Pharmacology Research Unit, Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, 5510 Nathan Shock Drive, Baltimore, MD 21224-6823, USA. - - 2013
Salvinorin A is a kappa opioid agonist and the principal psychoactive constituent of the plant Salvia divinorum, which has increased in popularity as a recreational drug over the past decade. Few human studies have examined salvinorin A. This double-blind, placebo-controlled study evaluated the dose-related effects of inhaled salvinorin A in ...
Hu Hui-Hsin - - 2012
The 3-D morphological change has gained increasing significance in recent investigations on human fetal brains. This study uses a pair of new indices, the shape index (SI) and curvedness index (CVD), to quantify 3-D morphological changes in developing brains from 22 to 33 weeks of gestation. The SI was used to ...
Zhao Xiaoli - - 2012
Genome instability is a hallmark of cancer. Diffuse large B-cell lymphoma (DLBCL) is the most common form of non-Hodgkin lymphoma with high levels of chromosomal aberrations. The purpose of this study was to characterize chromosomal aberrations in Chinese DLBCL patients and to compare chromosomal abnormalities between germinal centre B-cell-like (GCB) ...
Hur Jinyoung J Division of Metabolism and Functionality Research, Korea Food Research Institute, Seongnam-si, Gyeonggi-do, Republic of - - 2013
The β-amyloid (Aβ) peptide aggregation with accompanying oxidative stress plays the major role in the pathogenesis of Alzheimer's disease (AD). Some natural compounds, including borneol, shed promising light on AD treatment. The present study was designed to investigate the antioxidative, antiapoptotic effects, and neuroprotection of borneol in human neuroblastoma cells ...
Jones Bernard L BL Nuclear/Radiological Engineering and Medical Physics Programs, Woodruff School of Mechanical Engineering, Georgia Institute of Technology, Atlanta, GA 30332-0405, - - 2012
This report presents the first experimental demonstration, to our knowledge, of benchtop polychromatic cone-beam x-ray fluorescence computed tomography (XFCT) for a simultaneous determination of the spatial distribution and amount of gold nanoparticles (GNPs) within small-animal-sized objects. The current benchtop experimental setup successfully produced XFCT images accurately showing the regions containing ...
Liu Liming - - 2012
PURPOSE: P. pastoris has previously been genetically engineered to generate strains that are capable of producing mammalian-like glycoforms. Our objective was to investigate the correlation between sialic acid content and pharmacokinetic properties of recombinant TNFR2:Fc fusion proteins generated in glycoengineered P. pastoris strains. METHODS: TNFR2:Fc fusion proteins were generated with ...
Willems E - - 2012
Routine detection of extended-spectrum β-lactamase (ESBL) production by AmpC-producing Enterobacteriaceae in microbiology laboratories is still a problem. The aim of this study was to compare the performance of four different phenotypic ESBL confirmation assays within this group of Enterobacteriaceae. A total of 83 AmpC-inducible Enterobacteriaceae were included in this study ...
Kowalczyk Keith J - - 2012
OBJECTIVES: Although most prostatectomy studies emphasize optimal nerve-sparing dissection planes, subtle technical variation also affects functional outcomes. The impact of minimizing assistant/surgeon tension on urinary function has not been quantified. We assess urinary function after attenuating neurovascular bundle (NVB) and rhabdosphincter tension during robotic-assisted radical prostatectomy (RARP). METHODS: Retrospective study ...
Singh Atul P - - 2012
Novel, high "turn-on" Hg(2+) and O(2)(-) fluorescence behaviour (∼25-fold) with probes bearing [S(thi)N(py)] and [S(thi)N(py)N(py)] binding receptors, joined by oxidizable sulphides, may involve S-bound transient ROS species; such optical O(2)(-) behaviour operates moderately in neuroblastoma.
Thorisdottir Asa Vala - - 2012
AIM: Revised infant dietary recommendations from the Icelandic Nutrition Council (11) are outlined in a booklet provided during free postnatal care. These focus on increasing the duration of exclusive and total breastfeeding and reducing cow's milk consumption. This study explored whether maternal education and other parental factors affected whether mothers ...
Wong A K - - 2012
Although variation in the KIT gene is a common cause of white spotting among domesticated animals, KIT has not been implicated in the diverse white spotting observed in the dog. Here, we show that a loss-of-function mutation in KIT recapitulates the coat color phenotypes observed in other species. A spontaneous ...
Harper J - - 2012
Surface melt on the Greenland ice sheet has shown increasing trends in areal extent and duration since the beginning of the satellite era. Records for melt were broken in 2005, 2007, 2010 and 2012. Much of the increased surface melt is occurring in the percolation zone, a region of the ...
Landré Vivien - - 2012
Understanding the determinants for site-specific ubiquitination by E3-ligase components of the ubiquitin-machinery is proving to be a challenge. Here we investigate the role of an E3-ligase docking site (Mf2-domain) in an intrinsically disordered domain of IRF-1, a short-lived IFN-γ regulated transcription factor, in ubiquitination of the protein. Ubiquitin modification of ...
Tabak Nili - - 2012
AIMS AND OBJECTIVES: To investigate the intentions of nurses and nursing students to telling the truth to patients and families, based on the Theory of Planned Behavior which examines intention to perform behaviours. BACKGROUND: In recent decades, the perception that patients have a moral and legal right to truthful and ...
Bhatti Irfan - - 2012
We performed a retrospective chart review of 50 youths with Autism Spectrum Disorder (ASD), prescribed amitriptyline (AMI) for hyperactivity and impulsivity. Data was systematically extracted from 50 outpatient clinic charts, including AMI treatment duration, dose, trough levels and adverse events. Mean age was 9.4 years (4.6-17.9); 40 were males and 10 ...
Bradley Robert H - - 2012
This study used data from the NICHD Study of Early Child Care and Youth Development to examine relations between parenting, self-control and externalizing behavior from early childhood to mid-adolescence (N = 956; 49.9 % male). Results indicated that maternal sensitivity, parental harshness and productive activity are related to externalizing problems but that patterns ...
Kute Vivek B - - 2012
BACKGROUND: Economic constraints in operating an effective maintenance dialysis program leaves renal transplantation as the only viable option for end-stage renal disease patients in India. Kidney paired donation (KPD) is a rapidly growing modality for facilitating living donor (LD) transplantation for patients who are incompatible with their healthy, willing LD. ...
Bongio Matilde - - 2012
Injectable bone substitutes (IBSs) represent an attractive class of ready-to-use biomaterials, both ceramic- and polymer-based, as they offer the potential benefit of minimally invasive surgery and optimal defect filling. Although in vitro assessments are the first step in the process of development, the safety and efficacy of an IBS strongly ...
Ebrahimizadeh Walead - - 2012
Vibrio cholerae is considered one of the major health threats in developing countries. Lack of efficient vaccine, short incubating time of the disease, and bacterium ability to survive in aquatic environment have made cholera one of the most epidemic diseases yet known. The lipopolysaccharide is one of the bacterium key ...
Yadav Pankaj - - 2012
Although, circadian clocks are believed to be involved in the regulation of life-history traits such as pre-adult development time and lifespan in fruit flies Drosophila melanogaster, there is very little unequivocal evidence either to support or refute this. Here we report the results of a long-term study aimed at examining ...
Yu Q - - 2012
BACKGROUND: Combined dexamethasone and tropisetron has been reported more effective than a single drug therapy in preventing postoperative nausea and vomiting (PONV). However, the safety use of dexamethasone has been questioned recently because of the risk of secondary adrenal deficiency. Therefore, we hypothesized that combined tropisetron and methylprednisolone, a short-lasting ...
Wang Xian-Huo - - 2012
Objective: The purpose of this study was to investigate the maximum tolerated dose (MTD), dose-limiting toxicity (DLT), and pharmacokinetics of ursolic acid liposomes (UAL), as a new drug, in healthy adult volunteers and patients with advanced solid tumors. Methods: All subjects received a single-dose of UAL (11, 22, 37, 56, ...
Hall Andrew Rennie - - 2012
Hall A R, Tsochatzis E, Morris R, Burroughs A K & Dhillon A P (2012) Histopathology Sample size requirement for digital image analysis of collagen proportionate area in cirrhotic livers Aims:   The requirements for adequate cirrhotic liver biopsy size have not been established for quantitative fibrosis measurements (collagen proportionate area: ...
Montano Simone - - 2012
Little is known about coral diseases in the Indian Ocean region, especially in the Republic of Maldives. This study aimed at documenting the presence of coral diseases in the archipelago of the Maldives. Surveys for lesions in scleractinians conducted at 8 sites around Magoodhoo Island (Faafu Atoll) in October and ...
Sun Yi Y Division of Radiation and Cancer Biology, Department of Radiation Oncology, University of Michigan, 4424B Medical Science-I, 1301 Catherine Street, Ann Arbor, MI 48109, USA. - - 2013
SAG (Sensitive to Apoptosis Gene), also known as RBX2 (RING box protein 2), ROC2 (Regulator of Cullins 2), or RNF7 (RING Finger Protein 7), was originally cloned in our laboratory as a redox inducible antioxidant protein and later characterized as the second member of the RBX/ROC RING component of the ...
Capes-Davis Amanda - - 2012
Continuous human cell lines have been used extensively as models for biomedical research. In working with these cell lines, researchers are often unaware of the risk of cross-contamination and other causes of misidentification. To reduce this risk, there is a pressing need to authenticate cell lines, comparing the sample handled ...
Korte Julia - - 2012
Antibody producing B-cells are an essential component of the immune system. In contrast to human and mice where B-cells develop in the bone marrow, chicken B-cells develop in defined stages in the bursa of Fabricius, a gut associated lymphoid tissue (GALT). In order to gain a better understanding of critical ...
Chankanka Oitip - - 2012
OBJECTIVE: To examine risk factors for non-cavitated caries, as well as cavitated caries. METHODS: Subjects were participants in the Iowa Fluoride Study cohort. Dietary data were collected at 36, 48, and 60 months old using 3-day dietary diaries, and a dental examination was conducted at about age 5. We compared ...
Yoshino K - - 2012
The aim of this study was to investigate risk factors with age in the long-term prognosis of autotransplantation of teeth with complete root formation at dental clinics. Participating dentists were asked to provide information on transplantations they had undertaken from 1 January 1990 to 31 December 2010. Data on a ...
Turková Kristýna - - 2012
Eleven strains of Lactobacillus collected in the Culture Collection of Dairy Microorganisms (CCDM) were evaluated for selected probiotic properties such as survival in gastrointestinal fluids, antimicrobial activity, and competition with non-toxigenic Escherichia coli O157:H7 for adhesion on Caco-2 cells. The viable count of lactobacilli was reduced during 3-h incubation in ...
Delko T - - 2012
Roux-en-Y gastric bypass (RYGB) is the gold standard in bariatric surgery. The effect of the procedure is based on restriction, malabsorption and changes in hormonal axis. Ghrelin is an important appetite hormone which is produced mainly in the gastric fundus. By adding a resection of the gastric fundus, we hypothesized ...
Hayashi Shinya S Department of Orthopaedic Surgery, Kobe University Graduate School of Medicine, 7-5-1 Kusunoki-cho, Chuo-ku, Kobe, 650-0017, Japan. - - 2012
Several studies have reported a risk of dislocation in obese patients after total hip arthroplasty. In this study, we evaluated the interaction between obesity and dislocation by kinematic analysis using a navigation system. The intraoperative range of motion (ROM) and postoperative impingement-free ROM were measured in 38 patients, and we ...
Cho Byoung-Soo BS Department of Pediatrics, School of Medicine, Kyung Hee University, Hoegi-dong #1, Dongdaemun-gu, Seoul, 130-702, - - 2013
Since 1998, urine screening tests have been performed on school children in Korea. We report the findings of the screening program that analyzed patients with proteinuria and/or hematuria. Between 1999 and 2008, 5,114 children were referred to pediatric nephrologists at seven nationwide hospitals. Renal biopsies were performed on 1,478 children ...
Keane Sarah C - - 2012
Nonstructural protein (nsp) 3 is the largest of 16 nsps translated from the murine hepatitis virus (MHV) genome. The N-terminal most domain of nsp3, nsp3a, has been identified by reverse genetics as a likely binding partner of MHV nucleocapsid protein. Here we report the backbone and side chain resonance assignments ...
Reito Aleksi - - 2012
The prevalence of total hip arthroplasty in young patients is small but increasing. We analyzed the results of metal-on-metal hip resurfacing (MMHR) in patients aged 40 years or less. In total 74 operations were performed on 64 patients. Mean age at operation was 33.2 years. HHS averaged 92.3 points at latest follow-up, ...
Faddy H M - - 2012
Background and Objectives  In Australia, the risk of transfusion-transmitted malaria is managed through the identification of 'at-risk' donors, antibody screening enzyme-linked immunoassay (EIA) and, if reactive, exclusion from fresh blood component manufacture. Donor management depends on the duration of exposure in malarious regions (>6 months: 'Resident', <6 months: 'Visitor') or a history ...
Werth Martin - - 2012
The transformation from self-supporting lianas to host-supported climbing lianas is related to re-allocation of biomass and nutrients among plant organs. Therefore, first, variations in leaf mass per area (LMA), leaf carbon and nitrogen allocation and (13)C and (15)N natural abundances were analysed among three tropical Passiflora species (P. edulis, P. ...
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