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Artner J - - 2012
Spinal injections are a treatment option in the conservative management of degenerative spinal disorders. The indications must be critically reviewed for every patient. Treatment with injections for painful spinal disorders should be a part of interdisciplinary treatment regimes. The diagnostic value varies between injection procedures. A large number of imaging ...
Erlenwein J - - 2012
BACKGROUND: The aim of this investigation was to describe the effects of standardization and central control of the processes involved in postoperative pain management from patient and employee perspectives. MATERIALS AND METHODS: Patients (n = 282/307) and respective hospital staff (n = 149/119) evaluated the processes, the quality of postoperative pain management and result ...
- - 2012
Tobacco use remains the single largest preventable cause of death and disease in the United States. According to the 2010 U.S. Surgeon General's report, approximately 443,000 U.S. adults die from smoking-related illnesses each year. In addition, smoking has been estimated to cost the United States $96 billion in direct medical ...
Erker C G - - 2012
Life-threatening pediatric emergencies are rare events in which precise, correct and fast drug dosing is essential. Intravenous drugs are most commonly dosed based on the child's weight in mg/kg. Numerous tools exist for aiding the physician in the error prone calculation, none of which meet all criteria for the perfect ...
Horvat Predrag - - 2012
A multistage system for poly(hydroxyalkanoate) (PHA) production consisting of five continuous stirred tank reactors in series (5-CSTR) with Cupriavidus necator DSM 545 as production strain was modelled using formal kinetic relations. Partially growth-associated production of PHA under nitrogen limited growth was chosen as modelling strategy, thus the Luedeking-Piret's model of ...
Seidel R - - 2012
This article reports the successful use of C1 esterase inhibitor in the treatment of capillary leak syndrome. The coincidence of exposure to latex during surgery and medication with ramipril led to prolonged shock complicated by secondary hyperfibrinolysis, capillary leak syndrome and multiple organ failure. Initial treatment according to relevant guidelines ...
Creveling J R - - 2012
Palaeomagnetic studies of Palaeoproterozoic to Cretaceous rocks propose a suite of large and relatively rapid (tens of degrees over 10 to 100 million years) excursions of the rotation pole relative to the surface geography, or true polar wander (TPW). These excursions may be linked in an oscillatory, approximately coaxial succession ...
Tsuboi Nobuo - - 2012
BACKGROUND: Studies have suggested that obesity-related glomerulopathy (ORG) is one of the important disease entities leading to end-stage renal disease. However, information is limited regarding the clinical features and renal outcomes of Japanese ORG patients. METHODS: Among the patients whose renal biopsy was performed at our institute during the past ...
Qu Fei - - 2012
Ag nanoclusters functioned by hyperbranched polyethyleneimine have been developed as a new fluorescent and colorimetric platform for sensitive and selective recognition of halide ions (e.g., Cl-, Br-, and I-). The recognition mechanism is based on the unique reactions between halide ions and the silver atoms. In particular, halide-induced oxidative etching ...
Palermo Francesco A - - 2012
Aloes are now considered a very interesting source of bioactive compounds among which phytosterols should play a major role. The present study is an attempt to investigate the hypocholesterolemic activity of Aloe vera associated with its impact on the reproductive status of juvenile goldfish. Therefore, the short- and long-term effects ...
Sumby Krista M - - 2012
AIM: To clone and characterise two related intracellular esterases from Oenococcus oeni and Lactobacillus hilgardii under wine-like conditions. METHODS AND RESULTS: The published genome sequences for O. oeni and Lb. hilgardii were used to identify, clone and purify putative esterase genes from these species designated EstCOo8 and EstC34 respectively. Both ...
D'Aco Kristin E KE Division of Genetics, Department of Pediatrics, University of Rochester School of Medicine and Dentistry, 601 Elmwood Ave, Box 777, Rochester, NY 14623, - - 2013
We identified a mitochondrial tRNA mutation (m.586 G > A) in a patient with renal failure and symptoms consistent with a mitochondrial cytopathy. This mutation was of unclear significance due to the absence of consistent reports of linkage to specific disease phenotypes and any data pertaining to its effects on mitochondrial function. ...
Brannelly Laura A - - 2012
Due in large part to recent global declines and extinctions, amphibians are the most threatened vertebrate group. Captive assurance colonies may be the only lifeline for some rapidly disappearing species. Maintaining these colonies free of disease represents a challenge to effective amphibian conservation. The fungal disease chytridiomycosis, caused by the ...
Zhang Aifeng - - 2012
Mutations in human ether-a-go-go-related gene (hERG) are responsible for congenital type-2 long QT syndrome (LQT2). We previously reported a truncated mutation of hERG, L539fs/47, which is composed of a 19 bp deletion mutation and a polymorphism A1692G in a Chinese family with LQT2. This mutation was found to cause a LQT2 ...
Taniguchi Yousuke - - 2012
Contrast media affects renal function, especially in the patients with advanced chronic kidney disease (CKD). The aim of this study was to investigate the characteristics of contrast induced exacerbation of renal dysfunction in the patients with advanced CKD (estimated glomerular filtration rate <30 ml/min/1.73 m(2)). We enrolled 102 advanced CKD patients who ...
Chao C M - - 2012
This study investigated the clinical characteristics of patients with skin and soft-tissue infections (SSTIs) due to Aeromonas species. Patients with SSTIs caused by Aeromonas species during the period from January 2009 to December 2011 were identified from a computerized database of a regional hospital in southern Taiwan. The medical records ...
Shahzad Waseem - - 2012
Mycoplasma conjunctivae are etiological agents of infectious keratoconjunctivitis (IKC), commonly known as pink-eye in domestic sheep, goats and other wild animals in many parts of the world. A few young Lohi lambs maintained at Livestock Experiment Station (LES), Bahadurnagar, Okara, Pakistan showed clinical signs and symptoms of conjunctivitis, keratitis, severe ...
Chu Shu-Hua - - 2012
Previous researches have showed that HSP90AA is important in ovarian cancer, but the mechanism of HSP90AA is still unknown. This study aimed to investigate the role of the potential therapy target protein HSP90AA1 in ovarian cancer. The level of HSP90AA1 in ovarian cancer SKOV3 cell line was altered by RNAi ...
Lysdahl Helle - - 2012
The purpose with this study was to investigate the effect of phenol red (PR) on chondrogenic and osteogenic differentiation of human mesenchymal stem cells (hMSCs). hMSCs were differentiated into chondrogenic and osteogenic directions in DMEM with and without PR for 2, 7, 14, 21, and 28 days. Gene expression of chondrogenic ...
Cheng Jiajia - - 2012
FeCl(3)-catalyzed aza-Prins-cyclization reaction of α-sulfonamido-allenes with aldehydes afforded 1,2,3,6-tetrahydropyridine or 2,5-dihydro-1H-pyrrole derivatives efficiently and highly selectively. The different regioselectivity is probably caused by the stabilizing effect of the phenyl group on the positively charged allylic intermediate.
Hadibarata Tony - - 2012
Armillaria sp. F022, a white-rot fungus isolated from decayed wood in tropical rain forest was used to biodegrade anthracene in cultured medium. The percentage of anthracene removal by Armillaria sp. F022 reached 13 % after 7 days and at the end of the experiment, anthracene removal level was at 87 %. The anthracene ...
Nielsen Sune F - - 2012
A reduction in the availability of cholesterol may limit the cellular proliferation required for cancer growth and metastasis. We tested the hypothesis that statin use begun before a cancer diagnosis is associated with reduced cancer-related mortality. We assessed mortality among patients from the entire Danish population who had received a ...
Kim Jong H - - 2012
An effective strategy for significantly increasing the organic transistor mobility with simultaneous reduction of threshold voltage utilizing discontinuous nano-patches of charge-transfer doping layer is demonstrated. By overlaying the nano-patches on top of a given semiconducting film, mobility and threshold voltage of p-type pentacene were remarkably improved to 4.52 cm(2) V(-1) ...
Hosmer Jaclyn M - - 2012
PURPOSE: To develop liquid crystalline phases with monoglycerides, and assess whether the monoglyceride type favors cutaneous over transdermal paclitaxel delivery. METHODS: BRIJ-based lamellar phases were prepared with 0.5% paclitaxel and 20% of either monocaprylin (LP-MC), monomyristolein (LP-MM) or monoolein (LP-MO). Skin electrical resistance, drug release and cutaneous delivery in vitro ...
Golestanirad Laleh - - 2012
This paper provides a theoretical assessment of the safety considerations encountered in the simultaneous use of transcranial magnetic stimulation (TMS) and neurological interventions involving implanted metallic electrodes, such as electrocorticography. Metal implants are subject to magnetic forces due to fast alternating magnetic fields produced by the TMS coil. The question ...
Joly Claire - - 2012
The impact of the insecticide chlorpyrifos (CPF) on the mammalian digestive system has been poorly described. The present study aimed at evaluating the effect of chronic, low-dose exposure to CPF on the composition of the gut microbiota in a Simulator of the Human Intestinal Microbial Ecosystem: the SHIME® and in ...
Urai H - - 2012
Delayed onset muscle soreness (DOMS) is reduced when the same exercise is repeated after a certain interval. However, the mechanism for this adaptation, called a repeated bout effect, is still not well understood. Recently, we showed that upregulated nerve growth factor (NGF) triggered by B2 bradykinin receptor (B2R) activation in ...
Xu Fang - - 2012
Multiplex PCR amplification of microsatellites has significantly increased the throughput and decreased the costs of genotyping. We have developed two highly polymorphic microsatellite multiplexes for Populus euphratica, the only tree species found in desert regions of Western China and adjacent Central Asian countries. The first of these multiplex kits comprises ...
Paletto Alessandro - - 2012
Values are generally defined as social facts that orientate individual and collective actions, and consequently influence political, economic and social systems. The evaluation of natural resource values is considered an important instrument to support decision making in environmental policy. The forest is an important renewable resource that provides a mix ...
Groch Kátia R - - 2012
Skeletal tissues of 49 humpback whales Megaptera novaeangliae that stranded between 2002 and 2011 along the Abrolhos Bank seashore and its adjacent waters in Brazil were studied. Twelve (24.5%) animals presented pathological changes in one or more bones. Degenerative changes and developmental malformations were most frequent (10.2% each), followed by ...
Danielsson K - - 2012
Background  The pathogenesis of oral lichen planus (OLP), a chronic inflammatory disease, is not fully understood. It is known that OLP has autoimmune features, and it is suggested to be an autoimmune disease. ELF-3 is involved in differentiation of keratinocytes and deregulated in different tumours and inflammatory diseases. CXCR-3 and ...
Issam Diab Mohammad - - 2012
Introduction The prevalence of diabetes mellitus (DM) in the UK increased in 2009 to 4 %, of which type-2 diabetes accounts for 85-95 % of all cases. In Qatar the prevalence of DM among the adult Qatari population in 2008 was 16.7 %; around four times higher than the prevalence in the UK. ...
Schemmer Peter P Department of General and Transplant Surgery, Ruprecht-Karls-University, Im Neuenheimer Feld 110, 69120 Heidelberg, Germany. - - 2013
It has been demonstrated that a wide variety of white blood cells and macrophages (i.e. Kupffer cells, alveolar and peritoneal macrophages and neutrophils) contain glycine-gated chloride channels. Binding of glycine on the receptor stimulates Cl(-) influx causing membrane hyperpolarization that prevents agonist-induced influx of calcium. Since platelet-aggregation is calcium-dependent, this ...
Koetz Kathrin R - - 2012
CONTEXT: Patients with primary adrenal insufficiency (PAI) and patients with congenital adrenal hyperplasia (CAH) receive weight-adapted standard glucocorticoid replacement therapy. Clinically, some patients appear more sensitive to therapeutic administration of glucocorticoids than others. Glucocorticoid sensitivity is at least partially genetically determined by polymorphisms of the glucocorticoid receptor (GR) and might ...
Zhang Degang D School of Automation, Northwestern Polytechnical University, Xi'an, - - 2013
Evolution of the brain has been an inherently interesting problem for centuries. Recent studies have indicated that neuroimaging is a powerful technique for studying brain evolution. In particular, a variety of reports have demonstrated that consistent white matter fiber connection patterns derived from diffusion tensor imaging (DTI) tractography reveal common ...
Shirakashi Sho - - 2012
We monitored infection by a brain-infecting myxozoan Kudoa yasunagai in hatchery-reared juvenile yellowtail Seriola quinqueradiata at a culturing site in Japan. Infection was detected by PCR and microscopic observation once every 1 to 4 wk during 2010 and 2011. In both years, we detected first infection in mid-July by PCR. ...
Osorio-Esquivel Obed - - 2012
The purpose of this study was to evaluate the hypolipidemic effect of a methanolic extract from Opuntia joconostle seeds fed to mice in a hypercholesterolemic diet. Acute toxicity of the methanolic extract was investigated by an established method. Phenolic composition and antioxidant activity were determined by high-performance liquid chromatography and ...
Oliveira Francisco P M - - 2012
This article presents an enhanced methodology to align plantar pressure image sequences simultaneously in time and space. The temporal alignment of the sequences is accomplished using B-splines in the time modeling, and the spatial alignment can be attained using several geometric transformation models. The methodology was tested on a dataset ...
Guo Lvhua - - 2012
The purposes of this study were to investigate the effects of erythropoietin (EPO) on the proliferation and function of human osteoblast cells (hFOB 1.19) cultured in vitro and to explore the underlying molecular mechanisms to provide a theoretical foundation for clinical applications of EPO in oral implant and restoration therapies. ...
Müller Werner E G - - 2012
The major structural and enzymatically active protein in spicules from siliceous sponges, e.g., for Suberites domuncula studied here, is silicatein. Silicatein has been established to be the key enzyme that catalyzes the formation of biosilica, a polymer that represents the inorganic scaffold for the spicule. In the present study, it ...
Ostertag Luisa M - - 2013
We examined whether flavan-3-ol-enriched dark chocolate, compared with standard dark and white chocolate, beneficially affects platelet function in healthy subjects, and whether this relates to flavan-3-ol bioavailability. A total of 42 healthy subjects received an acute dose of flavan-3-ol-enriched dark, standard dark or white chocolate, in random order. Blood and ...
Sittig Dean F - - 2012
Hospitals and clinics are adapting to new technologies and implementing electronic health records, but the efforts need to be aligned explicitly with goals for patient safety. EHRs bring the risks of both technical failures and inappropriate use, but they can also help to monitor and improve patient safety.
Chang Christopher - - 2012
Fungal diseases of the nose and sinuses encompasses a diverse spectrum of disease. Clinical manifestations are largely dependent upon the immune status of the host, as, given the ubiquitous nature of these organisms, exposure is unavoidable. Asymptomatic colonization of the nasal passages by fungi warrants no treatment and is common, ...
Lenart Anna - - 2013
The present study aimed to identify the effect of heavy metal concentration and soil pH on the abundance of the selected soil microorganisms within ArcelorMittal Poland steelworks, Cracow. The analysis included 20 soil samples, where the concentration of Fe, Zn, Cd, Pb, Ni, Cu, Mn, Cr and soil pH were ...
Miller Tobias - - 2012
PURPOSE: To gain mechanistic insights into drug loading and lyophilization of polymeric micelles. METHODS: PEGylated poly-4-(vinylpyridine) micelles were loaded with dexamethasone. Three different methods were applied and compared: O/W emulsion, direct dialysis, cosolvent evaporation. Micellar dispersions with the highest drug load were lyophilized with varying lyoprotectors: sucrose, trehalose, maltose, a ...
Amendola L L Department of Orthopedics and Traumatology, Spine Surgery, Maggiore Hospital, 'C. A. Pizzardi', Largo Nigrisoli 1, 40100 Bologna, Italy. - - 2013
Our aim is to define the role of embolization in the treatment of aneurysmal bone cyst of the spine in order to include this option in the decision making process. From April 2004 to November 2009, seven patients with primary aneurysmal bone cyst of the mobile spine treated by embolization ...
Cao Peng-Fei - - 2012
We report the first synthesis of a catenated polymer via a ring-expansion strategy, which is based on a supramolecularly templated initiator. The high yielding synthesis and simple isolation method will enable the investigation and development of this unique polymer system for further applications.
Li Lei L Department of Pathology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, - - 2013
Solid pseudopapillary neoplasm of the pancreas (SPN) is a rare low-grade malignant neoplasm. To our knowledge, SPN with prominent atypical multinucleated giant tumour cells (MNGTCs) has not yet been reported. We identified four cases of SPN with prominent atypical MNGTCs in a cohort of 62 cases of SPN (6.5%). The ...
Basilio Nuno - - 2012
The interaction between gamma-cyclodextrin and amphiphilic p-sulfonatocalix[4]-arenes was studied using NMR and isothermal titration calorimetry techniques. The results indicate that this calixarenes are able to form 1:1, 1:2 and 2:1 host-guest complexes with the cyclodextrin. The ROESY spectra suggest that the cyclodextrin binds the calixarenes trough the hydrophobic alkyl chains. ...
Leroy Roos - - 2012
OBJECTIVES: The objectives of this report were to survey the utilization of oral health care in children and adolescents with disabilities over a 7-year period and to compare these data with the utilization pattern of their peers without disabilities. For most countries, these data have not been published in the ...
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