Search Results
Results 801 - 850 of 2096
< 12 13 14 15 16 17 18 19 20 21 22 >
van der Pas R - - 2012
Cushing's syndrome is not only accompanied by an increased prevalence of cardiovascular disease, but also by a hypercoagulable state that is reflected by an increased incidence of venous thromboembolism. Overall, patients with CS have been reported to have a more than tenfold increased risk of developing venous thromboembolism. Moreover, the ...
Ma Jiebing - - 2012
Development of multimodal contrast agents for in vivo simultaneous multimodality imaging is an emerging interdiscipline that is paving the avenue towards the goal of personalized medicine. Herein, folic acid-conjugated silica-modified LaF3:Yb,Tm upconversion nanoparticles (UCNPs@SiO2-FA) with high La content in single particle were strategically designed and prepared for simultaneous targeting dual-modality ...
Ernst Sandra - - 2012
During development, morphogenetic processes require a precise coordination of cell differentiation, cell shape changes and, often, cell migration. Yet, how pattern information is used to orchestrate these different processes is still unclear. During lateral line (LL) morphogenesis, a group of cells simultaneously migrate and assemble radially organized cell clusters, termed ...
Moyer Bruce A - - 2012
In this paper, we present the case for molecular-recognition approaches for sulfate removal from radioactive wastes via the use of anion-sequestering systems selective for sulfate, using either liquid-liquid extraction or crystallization. Potential benefits of removing sulfate from the waste include improved vitrification of the waste, reduced waste-form volume, and higher ...
Clerici Graziano - - 2012
Abstract Objectives: To describe fetal and uterine hemodynamics in IUGR (intrauterine growth restriction) fetuses with hypercoiled umbilical cord. Methods: 102 pregnant woman with IUGR fetuses were enrolled in the study. In these cases hemodynamic indices and Doppler waveform profiles were evaluated. Results: In 7 of the enrolled cases of IUGR ...
Morelli Michele - - 2012
The aim of this retrospective study was to evaluate the efficacy of levonorgestrel intrauterine system-releasing (LNG-IUS) insertion in preventing atypical endometrial hyperplasia (AH) and endometrial cancer (EC) in symptomatic postmenopausal overweight/obese women. A total of 34 overweight/obese postmenopausal women, presenting abnormal uterine bleeding (AUB) and endometrial hyperplasia (EH), and who ...
Cai Hao - - 2012
Context: Fructus Corni, a traditional Chinese medicines, is derived from the dry ripe sarcocarp of Cornus officinalis Sieb. et Zucc (Cornaceae). Gallic acid, 5-hydroxymethylfurfural, morroniside, sweroside, loganin, cornin, 7-O-methyl-morroniside and cornuside are the active constituents of Fructus Corni used in many traditional Chinese medicines. This paper describes a sensitive and ...
Ribbens Wannes - - 2012
Abstract Perceived realism is considered a key concept in explaining the mental processing of media messages and the societal impact of media. Despite its importance, little is known about its conceptualization and dimensional structure, especially with regard to digital games. The aim of this study was to test a six-factor ...
Philipp Stephan - - 2012
The erythrocytic life cycle of Plasmodium falciparum is highly associated with severe clinical symptoms of malaria that causes hundreds of thousands of death each year. The parasite develops within human erythrocytes leading to the disruption of the infected red blood cell (iRBC) prior to the start of a new cycle ...
Snidvongs Kornkiat - - 2012
BACKGROUND: Osteitis is a feature of chronic rhinosinusitis (CRS) and often associated with recalcitrant disease. Radiological characteristics of osteitic sinus changes are commonly reported in practice but the clinical and pathologic significance is poorly defined. The objective of this study was to correlate the Kennedy Osteitis Score (KOS) to clinico-histologic ...
Purwanti Nanik - - 2012
Structuring protein foods to control the textural properties receives growing attention nowadays. It requires decoupling of the product properties such as water holding capacity and the mechanical properties from the actual protein concentration in the product. From an application point of view, both increasing and lowering the protein content in ...
Helgesen Ann K - - 2012
AIMS AND OBJECTIVE: To explore the role of relatives in the patient participation process for persons with dementia living in special care units in Norwegian nursing homes, with focus on everyday life. BACKGROUND: Studies exploring the experience of relatives of persons with dementia as to their role in the patient ...
Cherry Mohamad A - - 2012
Ifosfamide is an alkylating agent used to treat different types of malignancies including lymphomas, sarcomas and germinal cell tumors. Symptoms of ifosfamide neurotoxicity can range from mild confusion, dizziness and hallucination to overt encephalopathy. Various treatment options like methylene blue, albumin infusion and rarely hemodialysis have been used to treat ...
Faust Andrew C - - 2012
On October 25, 2011, Eli Lilly and Company announced the voluntary withdrawal of Xigris (drotrecogin alfa [activated]) following the negative results of its most recent clinical trial, the PROWESS-SHOCK study. The purpose of this commentary is to briefly review the history of drotrecogin alfa, discuss issues surrounding early cessation of ...
Zou Gang - - 2012
Previous studies indicate that epigenetic modifications play an important role in transcriptional regulation and contribute to the pathogenesis of gestational trophoblastic disease, including complete hydatidiform moles (CHMs). However, the underlying mechanisms and the critical genes have not been clearly identified. In the present study, we developed a novel technique, NotI ...
Simonato Alchiede - - 2012
Study Type - Therapy (outcome) Level of Evidence 2b What's known on the subject? and What does the study add? Upper Urinary Tract (UUT) Transitional Cell Carcinoma (TCC) is an uncommon disease and represents approximately 5% of all urothelial carcinomas. We report our series on 73 patients treated with Kidney Sparing ...
Outterson Kevin - - 2012
Food and Drug Administration (FDA) rules are often forged in crisis. After the 1937 sulfanilamide disaster that killed more than 100 people, Congress passed the Food, Drug, and Cosmetic Act (FDCA), requiring drugs to be safe and properly labeled. In 1962, a requirement was introduced for proof of drug efficacy ...
Panja Anangamohan - - 2012
A new symmetrical tricyanide building block mer-[Fe(bbp)(CN)(3)](2-) [1; bbp = bis(2-benzimidazolyl)pyridine dianion] has been prepared and structurally and magnetically characterized. It forms a new low-spin meridionally capped {Fe(III)L(CN)(3)} fragment with the tridentate bbp ligand. The reaction of 1 with Ni(II) salts in the presence of various ancillary ligands affords several ...
Kalimuthu Palraj - - 2012
The bacterial xanthine dehydrogenase (XDH) from Rhodobacter capsulatus was immobilized on an edge plane pyrolytic graphite (EPG) electrode to construct a hypoxanthine/xanthine biosensor that functions at physiological pH. Phenazine methosulfate (PMS) was used as a mediator which acts as an artificial electron transfer partner for XDH. The enzyme catalyzes the ...
Yu Gilbert - - 2012
The reaction of N(3)(CH(2))(3)Si(OTMS)(3) (TMS = SiMe(3)) with a dialkylammonium having hexynyl group , [FcCH(2)NH(2)CH(2)C(6)H(4)-4-O(CH(2))(4)C[triple bond, length as m-dash]CH]PF(6) (Fc = Fe(C(5)H(4))(C(5)H(5))), in the presence of dibenzo[24]crown-8-ether (DB24C8) and [Cu{Fe(CN)(4)}]PF(6) catalyst yielded the [2]rotaxane containing the dialkylammonium unit terminated by a bulky silyl group. Azides with a silsesquioxane group react ...
Mogelvang Rasmus - - 2012
OBJECTIVE: To evaluate the association of plasma osteoprotegerin (OPG) to hospitalisation for ischaemic heart disease (IHD), ischaemic stroke and all-cause mortality, and the effect of combining plasma OPG and high-sensitivity C-reactive protein (hsCRP). DESIGN: OPG and hsCRP concentrations were measured at baseline in a large Danish prospective community-based population study. ...
Cermak Naomi M - - 2012
BACKGROUND: Protein ingestion after a single bout of resistance-type exercise stimulates net muscle protein accretion during acute postexercise recovery. Consequently, it is generally accepted that protein supplementation is required to maximize the adaptive response of the skeletal muscle to prolonged resistance-type exercise training. However, there is much discrepancy in the ...
Jürgens Tim P - - 2012
Introduction:While inhalation of high-flow 100% oxygen is highly effective in cluster headache, studies on its efficacy in migraine are sparse and controversial.Case:We report the case of a 22-year-old patient with an eight-year history of strictly unilateral migraine without aura but cranial autonomic symptoms. She repeatedly responded completely to inhalation of ...
Nesterov Vitaly - - 2012
P-Trityl substituted Li/Cl phosphinidenoid tungsten(0) complex (OC)(5)W{Ph(3)CP(Li/12-crown-4)Cl} (3) was prepared via chlorine/lithium exchange in complex (OC)(5)W{Ph(3)CPCl(2)} (2) using (t)BuLi in the presence of 12-crown-4 in tetrahydrofuran (THF) at low temperature; complex 3 possesses significantly increased thermal stability in contrast to previously reported analogue derivatives. Terminal phosphinidene-like reactivity of 3 was ...
Cavazos-Rehg Patricia A - - 2012
BACKGROUND: Raising cigarette prices through taxation is an important policy approach to reduce smoking. Yet, cigarette price increases may not be equally effective in all subpopulations of smokers. PURPOSE: To examine differing effects of state cigarette price changes with individual changes in smoking among smokers of different intensity levels. METHODS: ...
Scepaniak Jeremiah J - - 2012
Addition of TEMPO to MCl3 (M = Fe, Al) results in the formation of MCl3(eta1-TEMPO) (M = Fe, 1; M= Al, 2). Both 1 and 2 oxidize alcohols to generate ketones or aldehydes, along with the reduced complexes, MCl3(eta1-TEMPOH) (M = Fe, 3; M= Al, 4). Complexes 1-4 have been ...
Chao Tzu-Chiao - - 2012
Over the last decades microfabricated bioanalytical platforms have gained enormous interest due to their potential to revolutionize biological analytics. Their popularity is based on several key properties, such as high flexibility of design, low sample consumption, rapid analysis time and minimization of manual handling steps, which are also of particular ...
Tanvetyanon T - - 2012
BackgroundSome reports suggest that patients with synchronous multiple foci of nonsmall-cell lung cancers (NSCLC) distributed in multiple lobes have a poor prognosis, even when there is no extrathoracic metastasis. The vast majority of such patients do not receive surgical treatment. For those who undergo surgery, prognostic factors are unclear.Patients and ...
Gantar Miroslav - - 2012
Abstract C-phycocyanin (C-PC) from Spirulina has been previously shown to have anticancer properties. Here, we report on anticancer activity of C-PC that was isolated from the novel cyanobacterium Limnothrix sp. 37-2-1. C-PC from this organism exhibited anticancer properties in our in vitro systems; however, the required doses were well above ...
Onishi Mami - - 2012
Studies of physician-nurse relationships have focused mainly on nurses' perceptions. Few studies have explored physicians' perceptions and related factors. This study had two aims: to describe physicians' perceptions of physician-nurse collaboration in Japan by focusing on attitudes toward collaboration and collaborative practice and to examine the effect of physicians' experiences ...
Foss Cristina - - 2012
In spite of commercially available products, the complete and sustained repair of damaged articular cartilage still presents various challenges. Amongst biomaterials proposed for cartilage repair, silk fibroin (SF) has been recently proposed as a material template for porous scaffolds cultured with chondrocytes and investigated in static and dynamic conditions. In ...
Wang Yan-Ying - - 2012
Abstract MicroRNAs are closely linked to tumor metastasis and let-7a may play a role in inhibiting the proliferation, invasion, and metastasis of lung cancer. In vitro, we aim to observe the impact of let-7a on the proliferation and invasion of the nonsmall cell lung cancer cell line 95D by constructing ...
Miller Dori J - - 2012
The first two weeks of neonatal life constitute a critical period for estrogen receptor-alpha (ESR1)-dependent uterine adenogenesis in the pig. A relaxin receptor (RXFP1)-mediated, lactocrine-driven mechanism was proposed to explain how nursing could regulate endometrial ESR1 and related gene expression events associated with adenogenesis in the porcine neonate during this ...
Kawahara Ryoko - - 2012
Going into reverse: An efficient and versatile catalytic system for the dehydrogenative oxidation of alcohols under extremely mild conditions is developed using a Cp*Ir complex with bipyridonate ligand as catalyst (see scheme, Cp*=pentamethylcyclopentadienyl). Reversible and repetitive transformation between 2-propanol and acetone by catalytic dehydrogenation-hydrogenation is also achieved.
Okamoto Curtis T - - 2012
This Editorial Focus highlights the findings of Yui, et al., in this issue, on the basolateral targeting and microtubule dependent targeting of aquaporin-2 water channels.
Tai Davina J - - 2012
BackgroundMaintenance of central blood volume (CBV) is essential for hemodynamic stability during hemodialysis (HD), though preservation of CBV is poorly understood. Pneumatic compression devices (PCDs) during HD may help maintain CBV.MethodsWe performed a randomized, crossover trial to determine the effect of PCDs on CBV during HD. Patients underwent two consecutive ...
Nakajima Takayuki - - 2012
Reactions of M(OAc)(2)·4H(2)O (M = Ni, Co) with 3-[benzyl(2-hydroxyethyl)amino]-1-propanol (H(2)L) in the presence of pyridine or triethylamine afforded novel homometallic icosanuclear wheel-shaped complexes [M(20)L(4)(HL)(4)(OAc)(28)] (M = Ni (1), Co (2)), which consist of a central M(II)(12) single-stranded, nearly planar loop with four peripheral [M(2)(HL)(OAc)(2)] fragments attached in an S(4) symmetrical ...
Rossow Ingeborg - - 2012
AIMS: This paper presents examples to illustrate the utility and limitations in the use of epidemiology in alcohol research and discusses some promising new directions. METHODS: Review of literature, concentrating on epidemiological alcohol research with relevance to public health. FINDINGS AND CONCLUSION: Epidemiology offers tools for assessment of causes and ...
Singh Neha - - 2012
Background: Prostate cancer is a leading cause of mortality in men worldwide especially in developing countries like India. The molecular mechanisms of the oncogenic signaling pathway(s) that are involved in prostate carcinogenesis play a crucial role in disease progression and persistence. There is an important role of signal transducer and ...
Yang Ya - - 2012
We demonstrate a pyroelectric nanogenerator (PENG) based on a lead zirconate titanate (PZT) film, which has a pyroelectric coefficient of about -80 nC/cm(2)K. For a temperature change of 45 K at a rate of 0.2 K/s, the output open-circuit voltage and short-circuit current density of the PENG reached 22 V ...
Zhang Shao-Lan - - 2012
The aims of this study were to observe the effect of exercise therapy on the function of the knee joint and the levels of cytokines and cytokine-related genes, specifically tumor necrosis factor-α (TNF-α), high sensitivity C-reactive protein (hs-CRP) and matrix metalloproteinase-3 (MMP-3), in the synovial joints of patients with knee ...
Hood Nancy E - - 2012
INTRODUCTION: Mandatory smoke-free policies in subsidized, multiunit housing (MUH) may decrease secondhand smoke exposure in households with the highest rates of exposure. Ideally, policies should be based on a strong understanding of factors affecting support for smoke-free policies in the target population to maximize effectiveness. METHODS: A face-to-face survey was ...
Dees D Dustin - - 2012
This case report describes concurrent ocular melanosis and limbal melanocytoma in a 6-year-old Golden Retriever dog. Three years prior, the pet was examined for progressive corneal pigmentation and started on topical Tacrolimus but was subsequently lost to followup. Current ophthalmic examination revealed a large pigmented limbal mass and severe corneal ...
Sun Li-Ping - - 2012
Chinese propolis (CP) is a natural product collected by honeybees and a health food raw material. Previous studies have shown that CP exhibits a broad spectrum of biological activities including anticancer, antioxidant, antibacterial, anti-inflammatory, and antiviral activities. The focuses of the present study were the standardization of CP and the ...
Burton Neil J - - 2012
OBJECTIVES: To compare osteotomy orientation relative to the sagittal and transverse planes of the tibia, and cis cortical damage for tibial plateau leveling osteotomy (TPLO) performed with the following aids: (1) Synthes TPLO jig and saw guide, (2) Slocum TPLO jig with ancillary Kirschner wires (SlocumK), and (3) Slocum jig ...
Rossini Giada - - 2012
West Nile virus (WNV) is currently circulating in several European countries and over the past decades, concomitant with enhanced surveillance studies and improved diagnostic capabilities, an increase in the geographical distribution and in the number of cases in Europe has been documented. In Italy, in 2011, 14 human cases of ...
Chan Cynthia Y - - 2012
OBJECTIVE:To determine whether thiazides have a chronic antihypertensive effect, in the absence of diuresis, in patients with severe renal disease (creatinine clearance <30 mL/min) or in those receiving dialysis.DATA SOURCES:A search was performed in PubMed, CENTRAL, and International Pharmaceutical Abstracts, using MeSH terms and/or key words. MeSH terms included kidney ...
Konermann Lars - - 2012
Electrospray ionization (ESI) generates intact gas phase ions from analytes in solution for mass spectrometric investigations. ESI can proceed via different mechanisms. Low molecular weight analytes follow the ion evaporation model (IEM), whereas the charged residue model (CRM) applies to large globular species. A chain ejection model (CEM) has been ...
Jiménez Josefina - - 2012
A divergent approach was used for the synthesis of dendritic structures based on a cyclotriphosphazene core with 12 or 24 hydroxyl groups, by starting from [N(3) P(3) (OC(6) H(4) OH-4)(6) ] and using an acetal-protected 2,2-di(hydroxymethyl)propionic anhydride as the acylating agent. Hydroxyl groups in these first- and second-generation dendrimers, G1-(OH)(12) ...
Danielsson Anna - - 2012
Abstract Purpose: The aim of this study was to identify gene expression profiles distinguishing alpha-particle (211)At and (60)Co irradiation. Materials and methods: Gene expression microarray profiling was performed using total RNA from confluent human fibroblasts 5 hours after exposure to (211)At labeled Trastuzumab monoclonal antibody (0.25, 0.5, and 1 Gy) ...
< 12 13 14 15 16 17 18 19 20 21 22 >