Search Results
Results 501 - 550 of 2099
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Bjørknes Ragnhild - - 2012
A randomized prevention study for ethnic minority mothers assessed the intervention effects of Parent Management Training-Oregon Model (PMTO) on maternal parent practices and child behavior. Ninety-six mothers from Somalia and Pakistan and their children aged 3 to 9 years were randomized to PMTO or a wait-list condition (WLC). Assessments were carried ...
Yamamoto Takanori - - 2012
In this previously reported multicenter study, teriparatide 20 μg/day was administered to elderly Japanese subjects (93 % female; median age 70 years) with osteoporosis and at high risk of fracture during a 12-month, randomized, double-blind, placebo-controlled period, which was followed by a 12 month treatment period in which all subjects received open-label teriparatide. Subjects ...
Elbur Abubaker Ibrahim - - 2012
Background Antibiotic prophylaxis is effective at reducing the risk of postoperative infection for nearly all types of surgery. Objective To audit the use of prophylactic antibiotics for elective surgery. Setting Khartoum Teaching Hospital, Sudan, a 1,000 bed tertiary level hospital. Method A prospective study was conducted over a 9 month period; ...
Didierlaurent D - - 2012
This study assesses the accuracy of prospective phase-gated PET/CT data binning and presents a retrospective data binning method that improves image quality and consistency. Respiratory signals from 17 patients who underwent 4D PET/CT were analysed to evaluate the reproducibility of temporal triggers used for the standard phase-based gating method. Breathing ...
Tsuzuki Shinobu - - 2012
The initial steps involved in the pathogenesis of acute leukemia are poorly understood. The TEL-AML1 fusion gene usually arises before birth, producing a persistent and covert preleukemic clone that may convert to precursor B cell leukemia following the accumulation of secondary genetic "hits". Here we show that TEL-AML1 can induce ...
Ihssen Niklas - - 2012
Perceptual processing of natural scene pictures is enhanced when the scene conveys emotional content. Such "motivated attention" to pleasant and unpleasant pictures has been shown to improve identification accuracy in non-speeded behavioural tasks. An open question is whether emotional content also modulates the speed of visual scene processing. In the ...
Burnett D J - - 2012
The aim of this study was to investigate the effect of processing route (i.e., quench cooling and ball milling) on the surface energy heterogeneity and surface chemistry of indomethacin (IMC). Recently developed inverse gas chromatography (IGC) methodology at finite concentrations was employed to determine the surface energy distributions of crystalline, ...
Lloyd Belinda - - 2012
AIMS: To assess the relationship between ambulance attendances, emergency department (ED) presentations and hospital admissions for acute alcohol intoxication and the timing of public holidays, sporting and social events. DESIGN: Time series analysis was used to explore trends in intoxication in the context of major events. SETTING: Population of Melbourne, ...
Kim Youngsoon - - 2012
Acidic water: The first monolayer of water on a Ru(0001) surface is anomalously acidic compared to bulk water, according to infrared and mass spectroscopic investigations of the water layer using ammonia as a probe for surface acidity. The observation suggests that acid-base chemistry may be quite different at the water-metal ...
Bossart Gregory D - - 2012
Necropsies were conducted on 4 Antillean manatees Trichechus manatus manatus that were stranded in single events on the coastal beaches of Puerto Rico from August 2010 to August 2011. Three manatees were emaciated and the gastrointestinal tracts were devoid of digesta. Microscopically, all manatees had severe widespread inflammatory lesions of ...
Fenwick Eva K - - 2012
PURPOSE: We are developing an item bank assessing the impact of diabetic retinopathy (DR) on quality of life (QoL) using a rigorous multi-staged process combining qualitative and quantitative methods. We describe here the first two qualitative phases: content development and item evaluation. METHODS: After a comprehensive literature review, items were ...
Caldarella Carmelo - - 2012
Fluorine-18-fluorodeoxyglucose positron emission tomography (FDG-PET) is a useful diagnostic tool for the staging of patients with multiple myeloma (MM). The aim of this study is to perform a systematic review of the usefulness of FDG-PET or PET/CT in monitoring response to treatment in patients with MM. A comprehensive computer literature ...
Mahmood Usama - - 2012
BACKGROUND: To study national trends in the mastectomy rate for treatment of early stage breast cancer. METHODS: We analyzed data from the Surveillance, Epidemiology, and End Results database, including 256,081 women diagnosed with T1-2 N0-3 M0 breast cancer from 2000 to 2008. We evaluated therapeutic mastectomy rates by the year ...
Ferri Gian Gaetano - - 2012
Conservative management of small vestibular schwannomas is frequently proposed as most tumours do not grow. Anyway, tumour growth is reported in 30-40 % of the cases, so that surgery is consequently generally proposed. We primarily observed 161 patients affected by unilateral vestibular schwannomas. All patients were examined by means of gadolinium-enhanced ...
Whitty Cc - - 2012
Abstract CASE HISTORY: A 13 kg 3.5-year-old male neutered Cocker Spaniel presented with a 6-day history of deteriorating hindlimb paresis. Approximately 10 weeks previously the owner reported removing a large number of barley grass seeds from the dog's coat and ears. Eight weeks later the dog was treated for pneumonia, based ...
Zador Zsolt - - 2012
BACKGROUND: The eyebrow craniotomy is a less invasive alternative approach for accessing anterior skull base lesions, compared to traditional and more extensive exposures. We give a stepwise description of this minimally invasive technique with discussion on the indications, limitations and key aspects of perioperative management. METHODS: Positioning of the head ...
Constantin J - - 2012
Over the last 25 years, lung imaging has changed our understanding of acute respiratory distress syndrome. Alveolar recruitment, hyperinflation, and positive end- expiratory pressure-induced changes in lung aeration have become evaluable using CT, PET, and ultrasonography. The data have revealed that patients differ, in that the required ventilator settings vary ...
Medici Valentina V Department of Internal Medicine, University of California Davis, Davis, CA 95817, USA. - - 2013
Alcoholic liver disease (ALD) is typically associated with folate deficiency, which is the result of reduced dietary folate intake, intestinal malabsorption, reduced liver uptake and storage, and increased urinary folate excretion. Folate deficiency favors the progression of liver disease through mechanisms that include its effects on methionine metabolism with consequences ...
Martín Mariana L - - 2012
Recent findings demonstrate that alkaline/neutral invertases (A/N-Invs), enzymes that catalyze the breakdown of sucrose into glucose and fructose, are essential proteins in plant life. The fact that different isoforms are present in multiple locations makes them candidates for the coordination of metabolic processes. In the present study, we functionally characterized ...
Hummel Thomas - - 2012
The study aimed to investigate the volume of the olfactory bulb (OB) in patients with temporal lobe epilepsy (TLE). Specifically, we wanted to see whether the olfactory deficit typically found in TLE patients also exerts a top-down influence on the OB. Twenty patients, and 20 age- and sex-matched healthy controls ...
Sahle Fitsum F - - 2012
PURPOSE: To improve the solubility and penetration of Ceramide AP (CER [AP]) into the stratum corneum that potentially restores the barrier function of aged and affected skin. METHODS: CER [AP] microemulsions (MEs) were formulated using lecithin, Miglyol® 812 (miglyol) and water-1,2 pentandiol (PeG) mixture as amphiphilic, oily and hydrophilic components, ...
de Schepper Evelien I T EI Department of General Practice, Erasmus MC, PO Box 2040, 3000 CA, Rotterdam, The Netherlands. - - 2013
A possible cause of hip pain is the presence of radiating pain from the higher lumbar spine. Identification of factors associated with hip pain arising from the lumbar spine would aid the physician. The first step in identifying possible factors is to look at the association between hip pain and ...
Newell Ben R - - 2012
Probability matching in sequential decision making is a striking violation of rational choice that has been observed in hundreds of experiments. Recent studies have demonstrated that matching persists even in described tasks in which all the information required for identifying a superior alternative strategy-maximizing-is present before the first choice is ...
Chen Qi-Mei - - 2012
H-FABP and A-FABP genes are considered as candidates for intramuscular fat (IMF) accretion. The aim of the present study was to assess the expression of H-FABP and A-FABP genes in m. longissimus dorsi (LD) and liver tissues of Laiwu and Lulai Black pig populations of different body weight (BW). Eighty-four ...
Aarnink A - - 2012
The cynomolgus macaque (Macaca fascicularis) is a model of choice among primates for the study of local adaptation processes because of its mixed and wide insular and continental distribution. In a previous study, by using 12 markers [5 microsatellites located in the major histocompatibility complex (MHC) region and 7 outside ...
Li Jiabei - - 2012
Wavelength tunability of lasers is one of the most important parameters for achieving practical applications such as optical communication, environmental monitoring, and spectroscopy analysis. A wide-wavelength tunable laser is demonstrated on a single non-doped CdSe nanowire (NW) without changing pumping intensity and position, but by simply gradually cutting the NW ...
Highton Jamie - - 2012
Abstract Acute carbohydrate-protein ingestion has been shown to improve steady-state endurance performance. This study compared the effects of carbohydrate and carbohydrate-protein ingestion on self-regulated simulated multiple-sprint sport performance. Nine participants completed two trials of a modified Loughborough Intermittent Shuttle Test involving 4 x 15 min blocks of regulated exercise followed by ...
Kessler Elizabeth R - - 2012
With a large, aging population in the USA and continued prolongation of life expectancy, treatment of cancer in the elderly will continue to be of importance. The most common cancer in men is prostate cancer, which is most often diagnosed in those over the age of 65 years. Initial therapies for ...
Sandall Simon - - 2012
This paper takes key insights from social psychologists and interrogates them as methodological tools for historians, applying these theories to a large-scale uprising that occurred in southern England in 1549. In a social order based on notions of paternalism and deference, a diverse band of rebels were able to forge ...
Yun Huifeng H Department of Epidemiology, University of Alabama at Birmingham, Birmingham, AL 35294, USA. - - 2013
Generic alendronate was approved in the United States on February 6, 2008. Medicare beneficiaries might pay for generic alendronate out-of-pocket without having claims submitted, resulting in misclassification of generic alendronate use in Medicare data. To estimate the completeness of generic alendronate use in 2008 Medicare Part D data; to identify ...
Rodríguez-Martínez Rafael - - 2012
A trial was conducted during the anestrous period in female goats to determine: (a) whether estrus can be induced in anestrous goats by administration of equine chorionic gonadotropic hormone (eCG) and PGF(2α) under pen conditions and (b) whether these sexually active female goats can elicit sexual arousal in sexually inactive ...
Giannakopoulou Efstathia - - 2012
Monocyte chemoattractant protein-1 (MCP-1) is implicated in promoting atherosclerotic diseases, including stroke. Therefore, several studies have investigated the association between variants of the MCP-1 gene and risk of atherosclerotic diseases. We sought to determine the occurrence of MCP-1 -2518A>G polymorphism in patients with ischemic stroke (IS), and studied its association ...
Santín M - - 2012
Abstract Cryptosporidium spp. are frequent parasites of livestock and companion animals, raising questions about the clinical significance of such infections. Cryptosporidium infections have a wide spectrum of clinical signs that can vary from asymptomatic to serious infection to death. In neonatal ruminants, cryptosporidiosis is considered an important disease characterised by ...
Reinisch Eva E Department of Psychology, Emory University, Atlanta, GA, USA. - - 2013
Listeners infer which object in a visual scene a speaker refers to from the systematic variation of the speaker's tone of voice (ToV). We examined whether ToV also guides word learning. During exposure, participants heard novel adjectives (e.g., "daxen") spoken with a ToV representing hot, cold, strong, weak, big, or ...
Wang Shi-Zhen - - 2012
A chemo-enzymatic synthesis method of S-citalopram was developed to overcome the disadvantage of relatively low selectivity of enzyme towards tertiary alcohols. The combination of kinetic resolution, cyclic resolution and stereoinversion synthesis was successfully applied in the asymmetric synthesis of the S-citalopram. Using the kinetic model to predict the cyclic resolution, ...
Tseng Wan-Ting - - 2012
The transection of the inferior alveolar nerve (IANx) produces allodynia in the whisker pad (V2 division) of rats. Ectopic discharges from injured trigeminal ganglion (TG) neurons and thalamocortical reorganization are possible contributors to the sensitization of uninjured V2 primary and CNS neurons. To test which factor is more important, TG ...
Nakajima Mitsunari - - 2012
The neural crest is a unique structure in vertebrates. Wnt1-cre and Wnt1-GAL4 double transgenic (dTg) mice have been used in a variety of studies concerning neural crest cell lineages in which the Cre/loxP or GAL4/UAS system was applied. Here, we show psychiatric disorder-related behavioral abnormalities and histologic alterations in a ...
Broda Agnieszka - - 2013
The isolation of rapidly growing mycobacteria (RGM), particularly Mycobacterium abscessus, from individuals with cystic fibrosis (CF) is associated with poor clinical outcome due to broad drug resistance and the difficulty of eradicating the organisms. Susceptibility testing is recommended to guide therapy. A disc diffusion method is used in the United ...
Scott Ian A - - 2012
Minimising the harm from inappropriate prescribing in older populations is a major urgent concern for modern healthcare systems. In everyday encounters between prescribers and patients, opportunities should be taken to identify patients at high risk of harm from polypharmacy and reappraise their need for specific drugs. Attempts to reconcile life ...
Oberg Elizabeth A EA Department of Pharmacology, University of Iowa Carver College of Medicine, Iowa City, Iowa 52242, - - 2012
Protein phosphatase 2A (PP2A), a ubiquitous and pleiotropic regulator of intracellular signaling, is composed of a core dimer (AC) bound to a variable (B) regulatory subunit. PP2A is an enzyme family of dozens of heterotrimers with different subcellular locations and cellular substrates dictated by the B subunit. B'β is a ...
Condie Allison G - - 2012
Myelination is a fundamental biological process in the vertebrate nervous system. Damage to or malformation of myelin can lead to various neurological diseases; for example, demyelination in the spinal cord is a major cause of paralysis of patients suffering from multiple sclerosis and related diseases. The ability to directly track ...
Lavezzi Jinny R JR Perinatal Research Center, Section of Neonatology, Department of Pediatrics, University of Colorado Denver School of Medicine, Aurora, - - 2013
Maternal undernutrition during pregnancy and placental insufficiency are characterized by impaired development of fetal pancreatic β-cells. Prolonged reduced glucose supply to the fetus is a feature of both. It is unknown if reduced glucose supply, independent of other complications of maternal undernutrition and placental insufficiency, would cause similar β-cell defects. ...
Petersen Tue Hvass - - 2012
Neurophysiological markers of the central control of gait in children with cerebral palsy (CP) are used to assess developmental response to therapy. Here we measure the central common drive to a leg muscle in children with CP. We recorded EMGs from the Tibialis Anterior (TA) muscle of 40 children with ...
Motti Elena - - 2012
o-Biaryl carbaldeydes and ketones are obtained through the one-pot reaction of o-aryl iodides with o-bromobenzyl alcohols under the catalytic action of Pd and norbornene, in the presence of a base. The same reaction can also give dibenzopyrans by Pd and norbornene catalysis with a different termination, leading to C-O ring ...
Aziz Monowar M Center for Immunology and Inflammation, The Feinstein Institute for Medical Research, Hofstra North Shore-LIJ School of Medicine, 350 Community Dr., Manhasset, NY 11030, - - 2013
Sepsis refers to severe systemic inflammation in response to invading pathogens. An overwhelming immune response, as mediated by the release of various inflammatory mediators, can lead to shock, multiple organ damage, and even death. Cytokines, proteases, lipid mediators, gaseous substances, vasoactive peptides, and cell stress markers play key roles in ...
Tamiya A - - 2012
BackgroundThis study was designed to determine the recommended dose of carboplatin-pemetrexed in elderly (≥75 years old), chemotherapy-naive patients with advanced nonsquamous nonsmall-cell lung cancer (NSCLC).Patients and methodsPatients received escalated doses of carboplatin and pemetrexed every 3 weeks for four cycles. Patients with an objective response and stable disease continued pemetrexed ...
Caprile Laura - - 2012
We report the results of a synchrotron-based high-resolution XPS study of the interaction of l-cysteine (Cys) with well-characterized colloidal gold nanoparticles (NPs, typical size 3-4 nm), which were pre-deposited on highly oriented pyrolytic graphite and then brought into contact with the aqueous solution of Cys by drop-casting. By comparison with ...
Lee Sung-Uk SU Division of Hematopoietic Stem Cell and Leukemia Research, Beckman Research Institute of the City of Hope, Duarte, CA, - - 2013
Hematopoietic stem cells (HSCs) are the most primitive cells in the hematopoietic system and are under tight regulation for self-renewal and differentiation. Notch signals are essential for the emergence of definitive hematopoiesis in mouse embryos and are critical regulators of lymphoid lineage fate determination. However, it remains unclear how Notch ...
Felser Andrea - - 2012
Dronedarone is a new antiarrhythmic drug with an amiodarone-like benzofuran structure. Shortly after its introduction, dronedarone became implicated in causing severe liver injury. Amiodarone is a well-known mitochondrial toxicant.The aim of our study was to investigate mechanisms of hepatotoxicity of dronedarone in vitro and to compare them with amiodarone. We ...
Zuhl Micah - - 2012
Gastrointestinal distress, such as diarrhoea, cramping, vomiting, nausea and gastric pain are common among athletes during training and competition. The mechanisms that cause these symptoms are not fully understood. The stress of heat and oxidative damage during exercise causes disruption to intestinal epithelial cell tight junction proteins resulting in increased ...
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