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Results 401 - 450 of 2497
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Skinner Jonathan R - - 2012
Roughly two thirds of resuscitated cardiac arrests in children and youth are due to inherited heart diseases. The most commonly implicated are the cardiac ion channelopathies long QT syndrome, CPVT (catecholaminergic polymorphic ventricular tachycardia) and Brugada syndrome. Diagnosis is pivotal to further management of the child if he/she survives, and ...
Verdejo-García Antonio - - 2012
Objective:High doses of opiate substitution pharmacotherapy are associated with greater treatment retention and lower illicit drug consumption, although the neurobiological bases of these benefits are poorly understood. Dysfunction of the anterior cingulate cortex (ACC) is associated with greater addiction severity and mood dysregulation in opiate users, such that the beneficial ...
Delavaran H - - 2012
BACKGROUND: Clinical stroke trials with stem cell-based approaches aiming for trophic actions, modulation of inflammation and neuroprotection are ongoing. However, experimental studies also suggest that neuronal replacement by grafted neural stem cells (NSCs) and possibly by endogenous NSCs from the subventricular zone (SVZ) may restore function in the stroke-damaged striatum. ...
Chen Jing - - 2012
This paper introduces a new approach called double asynchronous orthogonal sample design (DAOSD) to probe intermolecular interactions. Specifically designed concentration series are selected according to the mathematical analysis to generate useful 2D correlated spectra. As a result, the interfering portions are completely removed and a pair of complementary sub-2D asynchronous ...
Roy Mukherjee Tapasi - - 2012
ABSTRACT: BACKGROUND: During the pandemic [Influenza A(H1N1)pdm09] period in 2009-2010, an influenza A (Inf-A) virus with H1N2 subtype (designated as A/Eastern India/N-1289/2009) was detected from a 25 years old male from Mizoram (North-eastern India). OBJECTIVE: To characterize full genome of the H1N2 influenza virus. METHODS: For initial detection of Influenza ...
Wang Shouxu - - 2012
An investigation into the ignitions and combustions of porous silicon (PS) nanoenergetic material array chips (nECs) at different ignition voltages was performed. The PS nECs were fabricated by integrating PS nanoenergetic material (nEMs) matrices and Cr-microbridges (microigniters) on the surface of silicon substrates. The combustion of PS nECs was in ...
Zhu Yan-Ping - - 2012
An I(2)-CF(3)SO(3)H synergistic promoted sp(3) C-H bond diarylation protocol was developed for the synthesis of 2,2-bis(4-(dimethylamino)phenyl)-1-aryl ethanones. The reaction performed well in the absence of any metal and ligand. It integrated three reactions with different mechanisms (iodination, Kornblum oxidation, and hydroarylation) in a single reactor.
Wee Kyung-Ryang - - 2012
Carborane based host materials were prepared to fabricate deep blue phosphorescence organic light emitting diodes (PHOLEDs), which constituted three distinctive geometrical structures stemming from the corresponding three different isomeric forms of carboranes, namely, ortho-, meta-, and para-carboranes. These materials consist of two carbazolyl phenyl (CzPh) groups as photo-active units on ...
Marschall Tobias - - 2012
MOTIVATION: Next-generation sequencing techniques have facilitated large scale analysis of human genetic variation. Despite the advances in sequencing speed, the computational discovery of structural variants is not yet standard. It is likely that many variants have remained undiscovered in most sequenced individuals. RESULTS: Here we present a novel internal segment ...
Sletten I N - - 2012
Four methods for measuring volar angulation in 5th metacarpal neck fractures were tested for validity and reliability. Mid-medullary canal measurement in the lateral view (method MC-90) has previously been proven valid in a cadaveric study, hence used as a reference to test validity of the latter three. These three yielded ...
Lee Soo-Keun - - 2012
Abstract Since the first introduction of botulinum toxin in cosmetic surgery, techniques and indications using botulinum toxin, mainly intramuscularly, have expanded greatly. Some of cosmetic surgeons are trying to inject the toxin intradermally and, anecdotally or through clinical studies, they sometimes show positive cosmetic results. The mechanism of which is ...
Han Yuchun - - 2012
The association behaviors of single-chain surfactant dodecyltrimethylammonium bromide (DTAB) with double hydrophilic block copolymers poly(ethylene glycol)-b-poly(sodium glutamate) (PEG113-PGlu50 or PEG113-PGlu100) were investigated using isothermal titration microcalorimetry, cryogenic transmission electron microscopy, circular dichroism, zeta potential, and particle size measurements. The electrostatic interaction between DTAB and the oppositely charged carboxylate groups of ...
Singh Sadhana - - 2012
OBJECTIVE: To investigate whether brain morphological differences exist between adult hypothyroid subjects and age matched controls using Voxel-Based Morphometry (VBM) with Diffeomorphic Anatomic Registration Through Exponentiated Lie algebra algorithm (DARTEL) approach. MATERIAL AND METHODS: High resolution structural MR images were taken in ten healthy controls and ten frank hypothyroid subjects. ...
Touchon Marie - - 2012
Clustered, regularly interspaced, short palindromic repeats (CRISPRs) are implicated in the defence against foreign DNA in various archaea and bacterial species. They have also been associated with slower spread of antibiotic resistance. However, experimental and evolutionary studies raise doubts about the role of CRISPRs as a sort of immune system ...
Adrian Julie Ann Luiz - - 2012
The nutrient composition of common guava, Psidium guajava L., and strawberry guava (waiwi), Psidium cattleianum var. lucidum, tree parts and fruits was determined during three seasons for six locations in Hawaii to assess guava as a potential feed for cattle. All guava plant parts were higher (p < 0.001) in ...
Kunishima Munetaka - - 2012
The reaction of 2-chloro-4,6-dimethoxy-1,3,5-triazine (CDMT) with various nitrogen-containing compounds, particularly tertiary amines (tert-amines), has been studied for the preparation of 2-(4,6-dimethoxy-1,3,5-triazinyl)trialkylammonium salts [DMT-Am(s)]. DMT-Ams derived from aliphatic tert-amines exhibited activity for the dehydrocondensation between a carboxylic acid and an amine to form an amide in a model reaction. Based on ...
Lee Haeok - - 2012
Purpose: The purpose of this article is to explain the evolution of a situation-specific theory developed to enhance understanding of health-related behaviors of Korean Americans (KAs) who have or are at risk for a chronic hepatitis B virus (HBV) infection. Organizing Construct: The situation-specific theory evolved from an integration of ...
da Silva Maria Stella Peccin - - 2012
ABSTRACT The purpose of this study was to evaluate the influence of helium-neon laser on skin injury in rabbits. For this purpose, fifteen New Zealand rabbits underwent bilateral skin damage in leg. Helium-neon laser light, at a fluence of 6 J/cm(2) and wavelength of 632.8 nm was applied on the ...
Alkjaer Tine - - 2012
This study investigated the function of the cruciate ligaments during a forward lunge movement. The mechanical roles of the anterior and posterior cruciate ligament (ACL, PCL) during sagittal plane movements, such as forward lunging, are unclear. A forward lunge movement contains a knee joint flexion and extension that is controlled ...
Yang Fanghong - - 2012
We exploited the synthesis of near-infrared (NIR) emitting ternary-alloyed CdTeSe and quaternary-alloyed CdZnTeSe quantum dots (QDs) with rod and tetrapod morphologies, which have tunable emission in the NIR electromagnetic spectrum. The morphologies of the QDs depended strongly on their growth kinetics, probably due to the coordinating ligands used in the ...
Das Priyadip - - 2012
In this work, we have rationally designed and synthesized two new reagents (L(1) and L(2) ), each bearing a pendant aldehyde functionality. This aldehyde group can take part in cyclization reactions with β- or γ-amino thiols to yield the corresponding thiazolidine and thiazinane derivatives, respectively. The intramolecular charge-transfer (ICT) bands ...
Bessinis Dimitrios P - - 2012
Purpose: This study evaluated the level of histamine in the interaction between the environment and the visual system during lifespan development, exploring potential sex differences. Methods: Male and female Wistar rats, reared in standard laboratory or enriched environment cages from birth to pre-puberty or adulthood, were sacrificed during the critical ...
Wang Yuna - - 2012
WRKY transcription factors are encoded by large gene families across the plant kingdom. So far, their biological and molecular functions in nonmodel plants, including pepper (Capsicum annuum) and other Solanaceae, remain poorly understood. Here, we report on the functional characterization of a new group I WRKY protein from pepper, termed ...
Lapi Francesco - - 2012
Adrenal insufficiency is a potential complication of therapy with inhaled corticosteroids (ICS). Although prior studies found the highest risk of adrenal insufficiency with fluticasone, a more potent ICS, these results might be explained by a channeling bias and concomitant exposure to oral corticosteroids.We re-examined the relationship between the use of ...
Suntharalingam Kogularamanan - - 2012
A new disubstituted terpyridine ligand and the corresponding tri-copper(II) complex have been prepared and characterised. The binding affinity and binding mode of this tri-copper complex (as well as the previously reported mono- and di-copper analogues) towards duplex DNA were determined by using UV/Vis spectroscopic titrations and fluorescent indicator displacement (FID) ...
Wu Jie - - 2012
An organosilane-directed alkyne-alkene reductive coupling of readily available propargyl silanes is used to access densely functionalized chiral allylsilanes. The divergent reactivity of the allylsilanes can be controlled to afford a range of novel carbocyclic ring systems through an intramolecular allylation, [3+2] annulation, and Sakurai-like homodimerization.
Lee In-Seob - - 2012
Abstract Background: Construction of an esophagojejunostomy is a major concern in totally laparoscopic total gastrectomy (TLTG). Use of a circular stapler can be technically challenging in laparoscopic procedures. We aimed to introduce our modified techniques and to assess the early outcomes following TLTG with side-to-side esophagojejunostomy using a linear stapler ...
Cho Hwa Jin - - 2012
Here, we report a case of lymphoepithelial tumor that developed in the sellar and suprasellar regions in a 56-year-old woman. The lesion was composed of abundant but benign squamous cell nests (Erdheim's nests) and heavy lymphoid tissue with well-developed lymphoid follicles. Therefore, it mimicked tonsil or adenoid tissue, but was ...
Gomes Inês M - - 2012
BACKGROUND: STEAP1 is over-expressed in several types of tumors, especially prostate cancer, where it is localized in the plasma membrane of epithelial cells, at cell-cell junctions. Its role in prostate carcinogenesis and its regulation in prostate cells remain unknown. Therefore, we propose to study the effect of sex hormones in ...
Guerra Arcadio - - 2012
In this study, a novel dimer-forming cyclic peptide composed exclusively by cyclic γ-amino acids with a saccharide-like outer surface is described. The antiparallel β-sheet type hydrogen bonding interactions responsible for the large association constant in non-polar solvents constitute a suitable model for a novel class of self-assembling peptide nanotubes.
Jaeger Johannes - - 2012
A central unresolved problem of evolutionary biology concerns the way in which evolution at the genotypic level relates to the evolution of phenotypes. This genotype-phenotype map involves developmental and physiological processes, which are complex and not well understood. These processes co-determine the rate and direction of adaptive change by shaping ...
Venegoni Ivan - - 2012
Polymer light-emitting diodes (PLEDs) have attracted growing interest in recent years for their potential use in displays and lighting fields. Nevertheless, PLED devices have some disadvantages in terms of low optoelectronic efficiency, high cost, short lifetimes and low thermal stability, which limit their final applications. Huge efforts have been made ...
Martin Keith R - - 2012
Abstract Consumption of polyphenol-rich fruits, for example, tart cherries, is associated with a lower risk of cardiovascular disease and cancer. This is due, in large part, to the diverse myriad bioactive agents, that is, polyphenol anthocyanins, present in fruits. Anthocyanin-rich tart cherries purportedly modulate numerous cellular processes associated with oncogenesis ...
De Padova Irene Paola - - 2012
The synthesis of silicene, graphene-like silicon, has generated very strong interest. Here, we reveal the growth of high aspect ratio, perfectly straight and aligned silicon nanoribbons, exhibiting pyramidal cross section. They are multi-stacks of silicene and show in angle-resolved photoemission cone-like dispersion of their π and π* bands, at the ...
Karbowiak Miroslaw - - 2012
Absorption emission and excitation spectra are measured and analyzed to achieve assignments of energy levels for 4fN ions in Ba2YCl7:RE3+ (RE = Pr, Nd, Tb, Dy, Ho, Er, and Tm) crystals. The experimental energy levels were analyzed in terms of the usual free-ion parameters and the crystal field (CF) ones, ...
Haldar Krishna Kanta - - 2012
We design well-defined metal-semiconductor nanostructures using thiol-functionalized CdTe quantum dots (QDs)/quantum rods (QRs) with bovine serum albumin (BSA) protein-conjugated Au nanoparticles (NPs)/nanorods (NRs) in aqueous solution. The main focus of this article is to address the impacts of size and shape on the photophysical properties, including radiative and nonradiative decay ...
Seo Keumyoung - - 2012
The change in the atomic nitrogen concentration on a semiconducting nanowire's surface and the consequent changes in the electrical characteristics of a nanowire transistor were investigated by exposing In(2)O(3) nanowires to nitrogen (N(2)) plasma. After plasma was applied at N(2) flow rates of 20, 40, and 70 sccm with a fixed ...
Portaccio E - - 2012
BACKGROUND AND PURPOSE: The development of treatment strategies for cognitive impairment in multiple sclerosis (MS) is still in its infancy. The objective of this prospective, non-randomized, pilot study was to assess the possible efficacy of treatment with natalizumab in comparison with interferon beta (IFNB) in a group of relapsing-remitting (RR) ...
Thompson Hayley S - - 2012
Low use of BRCA counseling and testing services among black women has been reported in several studies, even though such services may play an important role in reducing racial disparities in breast cancer. Surprisingly, little is known about the extent to which black women at high risk for BRCA mutations ...
Ding San-Yuan - - 2012
Covalent organic frameworks (COFs) represent an exciting new type of porous organic materials, which are ingeniously constructed with organic building units via strong covalent bonds. The well-defined crystalline porous structures together with tailored functionalities have offered the COF materials superior potential in diverse applications, such as gas storage, adsorption, optoelectricity, ...
Lee Jin - - 2012
One of the immunosuppressive responses when hepatocellular carcinoma (HCC) develops in mammals is defective proliferation in the spleen. The objective of this study was to investigate the protective effect of the Styrax japonica Siebold et al. Zuccarini (SJSZ) glycoprotein on the proliferation of splenocytes induced by diethlynitrosamine (DEN). To assess ...
Miles Rachael E H - - 2012
We compare and contrast measurements of the mass accommodation coefficient of water on a water surface made using ensemble and single particle techniques under conditions of supersaturation and subsaturation, respectively. In particular, we consider measurements made using an expansion chamber, a continuous flow streamwise thermal gradient cloud condensation nuclei chamber, ...
Guzar Igor - - 2012
  A series of experiments were conducted to highlight the mechanism of inhibition of hydrolysis and differences in hydrolysis among starches from different sources in the presence of green or black tea extract. The first experiment showed that black tea extract was more effective at reducing final viscosity for all ...
Akine Shigehisa - - 2012
The new acyclic tetraoxime ligand H(4)L(1), having two allyl groups at the terminal benzene rings, was designed and synthesized. The ligand H(4)L(1) was converted to five kinds of the trinuclear complexes, [L(1)Zn(3)(OAc)(2)], [L(1)Zn(2)La(OAc)(3)], [L(1)Zn(2)Ca(OAc)(2)], [L(1)Zn(2)Sr(OAc)(2)], and [L(1)Zn(2)Ba(OAc)(2)]. The terminal allyl groups were introduced so that the olefin metathesis could convert ...
Wang Hong-Ling - - 2012
Five unusual lactonic enamino ketones, gentiocrucines A-E (1-5), were isolated from Swertia macrosperma and S. angustifolia. Their structures were determined based on extensive spectroscopic analyses (IR, UV, MS, 1D- and 2D-NMR). By anti-HBV assay on the HepG 2.2.15 cell line in vitro, compound 1 inhibited both the secretion of hepatitis ...
Ahmad Farah - - 2012
South Asians comprise one of the fastest growing immigrant groups in North America. Evidence indicates that South Asian (SA) immigrant women are vulnerable to low rates of breast cancer screening. Yet, there is a dearth of knowledge pertaining to socioculturally tailored strategies to guide the uptake of screening mammography in ...
Martin Jeffrey S - - 2012
Elevated markers of systemic inflammation are associated with impaired glucose tolerance and type 2 diabetes mellitus. Enhanced external counterpulsation (EECP) has been shown to decrease circulating concentrations of pro-inflammatory markers in coronary artery disease patients. Here we provide novel evidence that EECP intervention also has a beneficial effect on circulating ...
Nakamura Yasuhiro - - 2012
BACKGROUND: Estrogen receptor beta (ERβ) has been demonstrated to be expressed in prostate carcinoma cells and estrogen signals through ERβ to act as a tumor suppressor in prostate cancer patients. ERβ is thought to regulate the cell cycle of prostate carcinoma cells by controlling the expression of cell cycle regulators ...
Bettinger Holger F - - 2012
The bisdecarbonylation of bridged α-diketones has turned into an important reaction for the photochemical generation of higher acenes, in particular under matrix isolation conditions. Here, a computational mechanistic analysis of the bisdecarbonylation of dibenzobicyclo[2.2.2]octadienedione 2 to anthracene 1 is presented. The study employed the B3LYP functional in conjunction with the ...
Nowaczyk MaƂgorzata J M - - 2012
Smith-Lemli-Opitz syndrome (SLOS) is a congenital multiple anomaly/intellectual disability syndrome caused by a deficiency of cholesterol synthesis resulting from a deficiency of 7-dehydrocholesterol (7DHC) reductase encoded by DHCR7. SLOS is inherited in an autosomal recessive pattern. It is characterized by prenatal and postnatal growth retardation, microcephaly, a variable degree of ...
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