Search Results
Results 301 - 350 of 2497
< 2 3 4 5 6 7 8 9 10 11 12 >
Enriquez G F - - 2013
The discrete typing units (DTUs) of Trypanosoma cruzi that infect domestic dogs and cats have rarely been studied. With this purpose we conducted a cross-sectional xenodiagnostic survey of dog and cat populations residing in 2 infested rural villages in Pampa del Indio, in the humid Argentine Chaco. Parasites were isolated ...
Sullivan Lisa M - - 2013
SMARCB1 gene alterations were first described in highly malignant rhabdoid tumors of the kidney, brain (atypical teratoid/rhabdoid tumor) and soft tissue. An increasing number of tumors have now shown loss of SMARCB1 protein expression by immunohistochemistry, including the majority of epithelioid sarcomas. However, investigations of SMARCB1 gene alterations in epithelioid ...
Miguel-Aliaga Irene - - 2012
Around 100 researchers gathered at the eighteenth EMBO Conference on 'The Molecular and Developmental Biology of Drosophila', which took place in Crete in June 2012. Whether deconstructing or integrating at the genetic, cellular or organ level, the talks highlighted the synergy of combining methods, approaches and disciplines in this increasingly ...
Rørth Pernille - - 2012
Cells can migrate individually or collectively. Collective movement is common during normal development and is also a characteristic of some cancers. This review discusses recent insights into features that are unique to collective cell migration, as well as properties that emerge from these features. The first feature is that cells ...
Han R C RC Newcastle Eye Centre, Royal Victoria Infirmary, Newcastle upon Tyne, - - 2012
Visual symptoms in older people can be complex and inadequately explained by eye pathology alone. Psychological and neurodegenerative processes may manifest as complex visual symptoms, and thus some patients may be poorly served by a purely ophthalmic approach. We have developed a novel multidisciplinary clinic with input from neurology, ophthalmology, ...
Bayoumi N H L NH Department of Ophthalmology, Faculty of Medicine, Alexandria University, 311 Horeya Avenue, Alexandria, Egypt. - - 2012
To study the additive value of deep sclerectomy to the procedure of combined trabeculotomy-trabeculectomy with mitomycin C (CTTM) for the treatment of primary congenital glaucoma. This study is a prospective, randomized case series. The study was conducted on 20 eyes of 20 children with primary congenital glaucoma presenting to the ...
Sehi M M Bascom Palmer Eye Institute, Department of Ophthalmology, University of Miami Miller School of Medicine, Palm Beach Gardens, FL, USA. - - 2012
The objective of this study is to assess whether baseline optic nerve head (ONH) topography and retinal nerve fiber layer thickness (RNFLT) are predictive of glaucomatous visual-field progression in glaucoma suspect (GS) and glaucomatous eyes, and to calculate the level of risk associated with each of these parameters. Participants with ...
Ting D S W DS The Australian E-Health Research Centre, Commonwealth Scientific Industrial Research Organization (CSIRO), Floreat, WA 6009, Australia. - - 2012
To evaluate the accuracy of different viewing monitors for image reading and grading of diabetic retinopathy (DR). Single-centre, experimental case series-evaluation of reading devices for DR screening. A total of 100 sets of three-field (optic disc, macula, and temporal views) colour retinal still images (50 normal and 50 with DR) ...
Liang X X State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, - - 2012
To explore a modified technique for silicone intubation for the repair of canalicular lacerations. The surgery was performed on 35 eyes in 35 adult patients from October 2007 to September 2009. Using a modified soft probe, silicone tubes were inserted through the lacrimal punctum and left in the bicanaliculi for ...
Therriault-Proulx François F Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, TX, - - 2012
The goal of this study was to develop a novel multi-point plastic scintillation detector (mPSD) capable of measuring the dose accurately at multiple positions simultaneously using a single optical transmission line. A 2-point mPSD used a band-pass approach that included splitters, color filters and an EMCCD camera. The 3-point mPSD ...
Ma Zhen Z Department of Microbiology, Cornell University, Ithaca, NY 14853-8101, - - 2012
Fur (ferric uptake regulator) is the master regulator of iron homeostasis in many bacteria, but how it responds specifically to Fe(II) in vivo is not clear. Biochemical analyses of Bacillus subtilis Fur (BsFur) reveal that in addition to Fe(II), both Zn(II) and Mn(II) allosterically activate BsFur-DNA binding. Dimeric BsFur co-purifies ...
Lu Shuo S Department of Chemistry and Biochemistry, University of Oklahoma, Stephenson Life Science Research Center, Norman, OK 73019, - - 2012
MacB is a founding member of the Macrolide Exporter family of transporters belonging to the ATP-Binding Cassette superfamily. These proteins are broadly represented in genomes of both Gram-positive and Gram-negative bacteria and are implicated in virulence and protection against antibiotics and peptide toxins. MacB transporter functions together with MacA, a ...
Raghavan Badrinarayanan B Department of Dermatology, University of Würzburg, Josef-Schneider Straße 2, 97080 - - 2012
Development of contact allergy requires cooperation of adaptive and innate immunity. Ni(2+) stimulates innate immunity via TLR4/MD2, the bacterial LPS receptor. This likely involves receptor dimerization, but direct proof is pending and it is unclear if related haptens share this mechanism. We reveal Co(2+) as second metal stimulating TLR4 and ...
Barr-Anderson D J DJ Arnold School of Public Health, University of South Carolina, Columbia, SC 29208, USA. - - 2013
Obesity interventions that involve family members may be effective with racial/ethnic minority youth. This review assessed the nature and effectiveness of family involvement in obesity interventions among African-American girls aged 5-18 years, a population group with high rates of obesity. Twenty-six databases were searched between January 2011 and March 2012, ...
Engel Philipp P Department of Ecology and Evolutionary Biology, Yale University, New Haven, CT, USA. - - 2013
The honey bee, Apis mellifera, harbors a characteristic gut microbiota composed of only a few species which seem to be specific to social bees. The maintenance of this stable and distinct microbial community depends on the social lifestyle of these insects. As in other animals, the bacteria in the gut ...
Christofi Theodoulakis T Department of Bbiological Sciences, University of Cyprus, Nicosia, - - 2013
The gastrointestinal tract is habitable by a variety of microorganisms and it is often a tissue inflicted by inflammation. Much discussion is raised in recent years about the role of microbiota in intestinal inflammation, but their role in intestinal cancer remains unclear. Here we discuss and extent our work on ...
Liu Shujuan S Key Laboratory for Organic Electronics & Information Displays (KLOEID), Nanjing University of Posts & Telecommunications (NUPT), Nanjing 210046, P R - - 2013
Homocysteine (Hcy) and cysteine (Cys) are two important kinds of amino acids in human bodies. Herein, we synthesized an iridium(III) complex-functionalized poly(N-isopropylacrylamide) and its hydrogel, which could be used as the excellent phosphorescent bioprobe for sensing Hcy and Cys. Their detection can be realized in aqueous system through the variations ...
Lyall D A M DA Tennent Institute of Ophthalmology, Gartnavel General Hospital, Glasgow, UK. - - 2012
To describe the incidence, features, management, and risk factors of post-intravitreal anti-VEGF endophthalmitis (PIAE) in patients undergoing treatment for exudative age-related macular degeneration in the United Kingdom. Prospective observational case control study. Forty-seven cases of PIAE were identified through the British Ophthalmological Surveillance Unit from January 2009 to March 2010. ...
Ziauddeen H H Department of Psychiatry, University of Cambridge, Cambridge, - - 2013
In this paper, we consider the concept of food addiction from a clinical and neuroscientific perspective. Food addiction has an established and growing currency in the context of models of overeating and obesity, and its acceptance shapes debate and research. However, we argue that the evidence for its existence in ...
Scott Nicola N Guy's and St Thomas' NHS Foundation Trust, London, UK. - - 2013
Associations between sleep duration and disturbance in infancy and early childhood and attention deficit hyperactivity disorder diagnoses were investigated. Data from the Avon Longitudinal Study of Parents and Children, a population-based prospective longitudinal birth-cohort study of children born in 1991-1992 in South-West England, were employed. Eight thousand, one hundred and ...
Yeh Gloria Y GY Osher Center for Integrative Medicine, Harvard Medical School, Boston, MA, - - 2013
Although exercise is an important component of heart failure management, optimal regimens, particularly in heart failure with preserved ejection fraction (HFPEF), are uncertain. Tai chi (TC) is a mind-body exercise that may have potential benefits but has not been studied in this population. The authors randomized 16 patients with HFPEF ...
He M M Key Laboratory of Cell Differentiation and Apoptosis of Ministry of Education, Department of Pathophysiology, Shanghai Jiao Tong University School of Medicine, Shanghai, - - 2013
Hypoxia-inducible factor 1 (HIF-1) is a crucial transcription factor for the cellular adaptive response to hypoxia, which contributes to multiple events in cancer biology. MicroRNAs (miRNAs) are involved in almost all cellular activities such as differentiation, proliferation, and apoptosis. In this work, we use miRNA microarrays to profile miRNA expression ...
Keil E E Institute of Medical Microbiology and Hospital Hygiene, Heinrich-Heine-University, Universitätsstr. 1, Düsseldorf, - - 2013
Autophagy is a lysosomal degradation pathway important for cellular homeostasis, mammalian development, cancer and immunity. Many molecular components of autophagy have been identified, but little is known about regulatory mechanisms controlling their effector functions. Here, we show that, in contrast to other p38 MAP kinase activators, the growth arrest and ...
McCrea Michael M Department of Neurosurgery and Neurology, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, USA. - - 2013
Sport-related concussion (SRC) is typically followed by clinical recovery within days, but reports of prolonged symptoms are common. We investigated the incidence of prolonged recovery in a large cohort (n = 18,531) of athlete seasons over a 10-year period. A total of 570 athletes with concussion (3.1%) and 166 controls ...
Lynch Susan V SV Colitis and Crohn's Disease Center, Division of Gastroenterology, Department of Medicine University of California, San Francisco, San Francisco, CA, USA. - - 2013
The composition of the gastrointestinal microbiome is increasingly recognized as a crucial contributor to immune and metabolic homeostasis-deficiencies in which are characteristic of cystic fibrosis (CF) patients. The murine model (CFTR (-/-) , CF), has, in previous studies, demonstrated characteristic CF gastrointestinal (GI) manifestations including slowed transit and significant upregulation ...
Ma Averil A Department of Medicine, University of California, San Francisco, California 94143-0451, USA. - - 2012
A20 (also known as TNFAIP3) is a potent anti-inflammatory signalling molecule that restricts multiple intracellular signalling cascades. Recent studies in three general areas have converged to highlight the clinical and biological importance of A20. First, human genetic studies have strongly linked polymorphisms and mutations in the gene encoding A20 to ...
Ach Emily E The Research Institute at Nationwide Children's Hospital, Columbus, OH 43205, - - 2013
The purpose of this study is to examine whether parental education, socioeconomic status, or family environment moderate the extent of academic achievement deficits in pediatric brain tumor survivors (PBTS) relative to classmate case-controls. PBTS are known to be at risk for cognitive and academic impairment; however, the degree of impairment ...
El-Sayed Hany A - - 2012
Highly ordered dimpled Ta (DT) nanotemplates, prepared by electrochemical anodization of Ta, were recently reported to be ideally suited for the fabrication of a Au nanoparticle (NP) array using a Au thin film dewetting method. Here, we provide guidance and understanding of the effect of the DT fabrication and Au ...
Son Kyung Hun - - 2012
In this review, the evaluation methods for the screening of depigmenting substrates were investigated. For this purpose, the evaluation method of tyrosinase, a key-enzyme of melanin biosynthesis, is most frequently used, but evaluating methods based on the regulation of cellular signal transfer factors, or the inhibition of melanosome transfer have ...
Li Tingting - - 2012
The reactivity of the cubane-type rare-earth methylidene complex [Cp'Lu(μ(3) -CH(2) )](4) (1, Cp'=C(5) Me(4) SiMe(3) ) with various unsaturated electrophiles was investigated. The reaction of 1 with CO (1 atm) at room temperature gave the bis(ketene dianion)/dimethylidene complex [Cp'(4) Lu(4) (μ(3) -CH(2) )(2) (μ(3) ,η(2) -O-CCH(2) )(2) ] (2) in 86 % ...
Kritchenkov Andreii S - - 2012
Palladium(II)-coordinated NCR(1) (R(1) = Et (1), NMe(2) (2), Ph (3)) species react smoothly with acyclic nitrones such as the ketonitrones Ph(2)C═N(O)R(4) (R(4) = p-MeC(6)H(4) (4), p-ClC(6)H(4) (5)) and the aldonitrone p-MeC(6)H(4)CH═N(O)Me (6) in the corresponding nitrile media. This reaction proceeds as a consecutive two-step intermolecular cycloaddition to give the mono- ...
Safdar Zeenat - - 2012
Pulmonary arterial hypertension (PAH) is characterized by pulmonary vascular remodeling that limits the ability of the pulmonary vascular bed to withstand the physiological changes of pregnancy. Historically, pregnancy in PAH carries a high risk to the parturient. Normal pulmonary vasculature can withstand the hemodynamic and physiological changes associated with pregnancy ...
Galmés Jeroni - - 2012
In a previous study, important acclimation to water stress was observed in the Ramellet tomato cultivar (TR) from the Balearic Islands, related to an increase in the water use efficiency through modifications in both stomatal (g(s) ) and mesophyll conductances (g(m) ). In the present work, the comparison of physiological ...
Arai Yonbon - - 2012
Controlling the adsorption behavior of bulk-phase self-assembling dye molecules at solid/liquid interfaces is of importance for application to various devices. Herein, we report an unexpected phenomenon on the adsorption behaviors of bulk J-aggregating water-soluble porphyrin diacids. A comparative study on the adsorption amounts of J-aggregated meso-tetrakis(4-sulfonatophenyl)porphyrin diacid from freshly prepared ...
Raphael Shyni - - 2012
A new aromatic carboxylate ligand, 4-[4-(9H-carbazol-9-yl)butoxy]benzoic acid (HL), has been synthesized by the replacement of the hydroxyl hydrogen of 4-hydroxy benzoic acid with a 9-butyl-9H-carbazole moiety. The anion derived from HL has been used for the support of a series of lanthanide coordination compounds [Ln = Eu (), Gd () ...
Zhou Yungang - - 2012
Developing approaches to effectively induce and control the magnetic states is critical to the use of magnetic nanostructures in quantum information devices but is still challenging. Here we have demonstrated, by employing the density functional theory calculations, an existence of infinite magnetic sheets with structural integrity and magnetic homogeneity. Examination ...
Clough Krishna B - - 2012
  Following a mastectomy, both the cosmetic and functional results can be impaired by the presence of a lateral "dog ear." This is a particular problem in women with a large body habitus giving an increased amount of adipose tissue lateral to the breast. The standard approaches to this operation ...
Nagaki Aiichiro - - 2012
We found that an integrated flow microreactor system enables the preparation of boronic esters bearing electrophilic functional groups using organolithium chemistry and that it allows for their use in Suzuki-Miyaura cross-coupling without intentionally added base. Based on this method, cross-coupling of two aryl halides bearing electrophilic functional groups was accomplished ...
Wang Zhiwei - - 2012
We report the atomic-scale structures and fluctuating dynamical behavior of size-selected Au55 clusters obtained by Aberration-Corrected Scanning Transmission Electron Microscopy (STEM) coupled with systematic STEM simulations. No high-symmetry structures (FCC polyhedron, icosahedron or decahedron) were observed in our statistical investigation. We find Au55 clusters that are characteristic of the theoretically ...
Schankin Christoph J - - 2012
Aim:The aim of this article is to generate hypotheses for the mechanism of pituitary adenoma headache.Patients and methods:Fifty-eight patients with pituitary adenoma were prospectively analysed for prevalence and manifestation of tumour headache. Intrapersonal and neoplasm-associated risk factors were assessed.Results:Twenty-four patients (41%) had tumour-attributed headache, seven had migraine-like, 11 tension-type headache-like ...
Hiemstra Tjisse - - 2012
Classically, silver (Ag) halides have been used to understand thermodynamic principles of the charging process and corresponding development of the electrical double layer (EDL). A mechanistic approach of the processes at the molecular level has not yet been done using advanced surface complexation modeling (SCM) as applied to metal (hydr) ...
Kim Junho - - 2012
Human mesenchymal stromal or stem cells (hMSCs) are being investigated for cell therapy in a wide range of diseases. MSCs are a potent source of trophic factors and actively remodel their immediate microenvironment through the secretion of bioactive factors in response to external stimuli such as oxygen tension. In this ...
Orlandi Ester M - - 2012
This study analyzed 140 patients with isolated del13q14 on interphase FISH (I-FISH), to identify subsets with a different progression risk and to assess the acquisition of additional chromosomal abnormalities (clonal evolution) in treatment-naïve del13q14 patients. A monoallelic deletion (del13qx1) was detected in 123 cases (88%), a biallelic deletion (del13qx2) in ...
Minguet Grégory - - 2012
Objective  To investigate the effects of the volatile anaesthetic sevoflurane on the release of total and active myeloperoxidase (MPO) by non-stimulated and stimulated polymorphonuclear neutrophils (PMNs) in whole blood from healthy horses. Study design  In vitro experimental study. Animals  Adult healthy horses. Methods  Samples of whole venous blood were collected ...
Kalubarme Ramchandra S - - 2012
This study suggests combustion synthesized Ce(1-x)Zr(x)O(2) (CZO; x = 0.1-0.5) as a new catalyst for the cathode in non-aqueous electrolyte based Li/O(2) cells. The spherical catalysts have a fluorite structure with a mean diameter of 5-17 nm. Zr doping into the ceria lattice leads to the reduction of Ce(4+) to Ce(3+), which further ...
Price Anthony N - - 2012
Cardiac MRI in neonates holds promise as a tool that can provide detailed functional information in this vulnerable group. However, their small size, rapid heart rate, and inability to breath-hold, pose particular challenges that require prolonged high-contrast and high-SNR methods. Balanced-steady state free precession (SSFP) offers high SNR efficiency and ...
Bliss Tim - - 2012
ABSTRACT: We are pleased to announce that Molecular Brain has been accepted by Thomson Reuters for tracking and is due to receive its first official Impact Factor in June 2013.
Abdu Kabir - - 2012
We show that DNA containing a conformationally-locked anti analogue of O(6)-alkylguanine is a poor substrate for human O(6)-methylguanine-DNA methyltransferase (MGMT) and the alkyltransferase-like protein, Atl1. This highlights the requirement for the syn conformation and rationalises why certain O(6)-alkylguanines are poor MGMT substrates.
Haugvik Marianne - - 2012
The aim of this article is to discuss how parallel therapy work with parents can be structured to achieve the goals of therapy with their children. Time-limited psychotherapy with children is a structured therapeutic method, where the goal and the number of sessions are contracted together with the child and ...
Khatri Khalil A - - 2012
Abstract Introduction: Fractional resurfacing with an Erbium: yttrium-aluminum-garnet (Er:YAG) 2940nm laser is an increasingly popular option for the treatment of the signs of facial photoaging, which include wrinkles as well as pigmentation issues and unwanted textural changes. Fractional treatment has produced favorable clinical responses, but with less complications and shorter ...
< 2 3 4 5 6 7 8 9 10 11 12 >