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Results 251 - 300 of 2501
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Eitaki Masato - - 2012
ABSTRACT: BACKGROUND: Anti-cancer drugs are widely used in cancer treatment frequently combined with surgical therapy and/or radiation therapy. Although surgery and radiation have been suggested to facilitate invasion and metastasis of tumor cells in some cases, there is so far little information about the effect of anti-cancer drugs on cellular ...
González-Sánchez M I - - 2012
An electrochemical approach to directly measure the dynamic process of H(2) O(2) release from cultures of Arabidopsis thaliana cells is reported. This approach is based on H(2) O(2 ) oxidation on a Pt electrode in conjunction with continuous measurement of sample pH. For [H(2) O(2) ] < 1 mM, calibration ...
Zhao Haiyan - - 2012
The objective of this study was to investigate the effects of grown origin, genotype and their interaction on multi-element fingerprints in wheat kernels to provide theoretical basis for geographical traceability. Ten varieties were grown in three different regions of China during the 2010-2011 growing seasons. The concentrations of ten elements ...
Aycan Zehra - - 2012
OBJECTIVE: There are a few studies regarding the prevalence of testicular adrenal rest tumors (TARTs) in boys and adolescent males with congenital adrenal hyperplasia (CAH), and there is little information regarding the treatment outcomes in patients with TARTs. The aim of this study was to determine the long-term treatment outcomes ...
Charlesworth T M - - 2012
An eight-month-old female English springer spaniel was presented with weight loss and severe haematochezia. Upper and lower endoscopy identified small intestinal inflammatory bowel disease and a vascular malformation within the descending colon. The colonic lesion was excised at coeliotomy and identified histopathologically as a colonic vascular ectasia. All clinical signs ...
Varga Csaba - - 2012
ABSTRACT: BACKGROUND: Identifying risk factors for Salmonella Enteritidis (SE) infections in Ontario will assist public health authorities to design effective control and prevention programs to reduce the burden of SE infections. Our research objective was to identify risk factors for acquiring SE infections with various phage types (PT) in Ontario, ...
Liang X X State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, - - 2012
To explore a modified technique for silicone intubation for the repair of canalicular lacerations. The surgery was performed on 35 eyes in 35 adult patients from October 2007 to September 2009. Using a modified soft probe, silicone tubes were inserted through the lacrimal punctum and left in the bicanaliculi for ...
Daly Blánaid - - 2012
Objective The aim of this study was to describe the dental services delivered by the Community Dental Service (CDS) of Tower Hamlets (TH) and City and Hackney (CH) for adult homeless people in 2009-2011, to assess if the service met its planned objectives and to report the outcomes of the ...
Jeya Marimuthu - - 2012
A novel type III polyketide synthase (RePKS) from Rhizobium etli produced a heptaketide pyrone using acetyl-CoA and six molecules of malonyl-CoA. Its catalytic efficiency (k(cat)/K(m) = 5230 mM(-1) min(-1)) for malonyl CoA was found to be the highest ever reported. Molecular dynamics studies revealed the unique features of RePKS.
Eljarrat A - - 2012
High-resolution monochromated electron energy loss spectroscopy (EELS) at subnanometric spatial resolution and <200 meV energy resolution has been used to assess the valence band properties of a distributed Bragg reflector multilayer heterostructure composed of InAlN lattice matched to GaN. This work thoroughly presents the collection of methods and computational tools ...
Nair Anroop B - - 2012
Treatment of nail diseases by topical drug delivery continues to draw much attention in the recent days. This study aims to systematically investigate the effect of constant voltage iontophoresis in the transungual drug delivery, using ciclopirox as a model drug. Preliminary permeation studies were carried out by applying constant voltage ...
Galán Amparo - - 2012
The purpose of this review is to provide a complete overview on the functions of the transcription/export factor Sus1. Sus1 is a tiny conserved factor in sequence and functions through the eukaryotic kingdom. Although it was discovered recently, research done to address the role of Sus1/ENY2 has provided in deep ...
Yan Jia - - 2012
In marine oxygen minimum zones (OMZs), ammonia-oxidizing archaea (AOA) rather than marine ammonia-oxidizing bacteria (AOB) may provide nitrite to anaerobic ammonium-oxidizing (anammox) bacteria. Here we demonstrate the cooperation between marine anammox bacteria and nitrifiers in a laboratory-scale model system under oxygen limitation. A bioreactor containing 'Candidatus Scalindua profunda' marine anammox ...
Varghese Shinto - - 2012
Three-in-one: A novel distyrylbenzene-based material forms J-type aggregates in single crystals with highly polarized and bright red emission, giving rise to optical gain narrowing, for which different mechanisms (amplified spontaneous emission, laser emission and stimulated resonance Raman scattering) are observed. These are correlated with the favorable intrinsic and macroscopic properties ...
- - 2012
Caries progression on proximal surfaces was arrested by both infiltration and sealing.
Gao Xue - - 2012
This paper describes a novel, simple method for the highly sensitive and selective detection of thrombin using fibrinogen (Fib) and CuInS(2) quantum dots (QDs) as biosensing probes. Water-soluble near-infrared CuInS(2) QDs capped by mercaptopropionic acid (MPA) were directly synthesized by a hydrothermal method. Addition of fibrinogen to the CuInS(2) QDs ...
Zakas Christina - - 2012
In many species, alternative developmental pathways lead to the production of two distinct phenotypes, promoting the evolution of morphological novelty and diversification. Offspring type in marine invertebrates influences transport time by ocean currents, which dictate dispersal potential and gene flow, and thus has sweeping evolutionary effects on the potential for ...
Shultz Leonard D - - 2012
Significant advances in our understanding of the in vivo functions of human cells and tissues and the human immune system have resulted from the development of 'humanized' mouse strains that are based on severely immunodeficient mice with mutations in the interleukin-2 receptor common γ-chain locus. These mouse strains support the ...
Chang Yung-Huang - - 2012
A three-dimensional Ni foam deposited with graphene layers on surfaces is used as a conducting solid support to load MoS(x) catalysts for electrocatalytic hydrogen evolution. The graphene sheets grown on Ni foams provide robust protection and efficiently increase the stability in acid. The superior performance of hydrogen evolution is attributed ...
Jang Tae-Won - - 2012
Objectives: This study aimed to investigate changes in the smoking rate among Korean adults from 1998-2009 by gender and occupational groups. Methods: Using the data from the first (1998), second (2001), third (2005) and fourth (2009) waves of the Korean National Health and Nutrition Examination Survey (KNHANES), we examined men ...
Prado Anselmo Del - - 2012
In this work the activation of transparent PS substrates by chlorosulfonation is described and their distribution in the subsurface region is analyzed. For this purpose XPS, FTIR-ATR and colorimetry have been used. It is shown that the electrophilic aromatic substitution of polystyrene in pure chlorosulfonic acid is extremely quick with ...
Abdulmalic Mohammad A - - 2012
Treatment of the diethyl ester of o-phenylenebis(oxamic acid) (opbaH(2)Et(2), ) with 5/6 equivalent of MeNH(2) in abs. EtOH results in the exclusive formation of the ethyl ester of o-phenylene(N'-methyl oxamide)(oxamic acid) (opooH(3)EtMe, ) in ca. 50% yield. Treatment of with four equivalents of [Me(4)N]OH followed by the addition of Cu(ClO(4))(2)·6H(2)O ...
Wagner Catherine E - - 2012
Although population genomic studies using next generation sequencing (NGS) data are becoming increasingly common, studies focusing on phylogenetic inference using these data are in their infancy. Here, we use NGS data generated from reduced representation genomic libraries of restriction-site-associated DNA (RAD) markers to infer phylogenetic relationships among 16 species of ...
He M M Key Laboratory of Cell Differentiation and Apoptosis of Ministry of Education, Department of Pathophysiology, Shanghai Jiao Tong University School of Medicine, Shanghai, - - 2013
Hypoxia-inducible factor 1 (HIF-1) is a crucial transcription factor for the cellular adaptive response to hypoxia, which contributes to multiple events in cancer biology. MicroRNAs (miRNAs) are involved in almost all cellular activities such as differentiation, proliferation, and apoptosis. In this work, we use miRNA microarrays to profile miRNA expression ...
Zhang Lu - - 2012
Multifunctional magnetic/upconversion luminescent mesoparticles, consisting of a Fe(3)O(4) nanoparticle core and a LaF(3):Yb(3+), Er(3+) nanocrystal shell, have been developed using a facile co-precipitation approach. Owing to their excellent superparamagnetic properties, superior T(2)-enhanced magnetic resonance effect and strong upconversion emissions, the as-formed mesoparticles have great potential in diverse medical diagnostics and ...
Gallagher J E - - 2012
Background and aim Dental professionals need adequate education in tobacco use prevention and cessation skills. The aim of this study was to identify the level of integration of tobacco education in undergraduate curricula of European dental schools.Method In 2009, a total of 197 European dental schools were identified through web-based ...
Scott Michael D - - 2012
Herein, we report the application of synthesized fluorescent, water soluble polymers for post-translational subtyping and differentiation of breast cancer cells in vitro. The fluorescence emission spectra from these polymers were modulated differently in the presence of conditioned cell culture media from various breast cancer cells. These polymers differentiate at a ...
White Joseph - - 2012
This article describes and analyzes the U.S. health care legislation of 2010 by asking how far it was designed to move the U.S. system in the direction of practices in all other rich democracies. The enacted U.S. reform could be described, extremely roughly, as Japanese pooling with Swiss and American ...
Kozaki Masatoshi - - 2012
A convergent method for the construction of shape-persistent nanoscale assemblies with conjugated backbones was developed. The copper-free Sonogashira coupling reaction was successfully applied to the formation of multiple covalent connections between conjugated terminals (iodide substituted aryl groups) of AB2-type outer components and four conjugated terminals (acetylenic bonds) of an inner ...
Weston Melissa C - - 2012
There is a need for a microfluidic pumping technique that is simple to fabricate, yet robust, compatible with a variety of solvents, and easy to control fluid flow. Redox-magnetohydrodynamics (MHD) offers these advantages. However, the presence of high concentrations of redox species, important for inducing sufficient convection at low magnetic ...
Tani Akira - - 2012
Objectives: Monoterpenes can positively or negatively affect human health depending on their concentrations. To assess the atmospheric risk for greenhouse workers, monoterpene concentrations and personal exposure in herb-growing greenhouses were measured. Methods: Monoterpene concentrations in a commercial greenhouse, where rosemary (Rosmarinus officinalis L.) and lavender (Lavandula angustifolia L.) were grown ...
Cumming Graeme S - - 2012
SUMMARY The relevance of spatial variation in the environment and host communities for parasite community composition is poorly documented, creating a need for additional case studies from which general principles can be developed. Avian malaria in southern African waterfowl has not previously been studied. As a first step towards documenting ...
Seymen Pinar - - 2012
Abstract: Objective. Acute ethanol intoxication has been shown to cause oxidative damage in many organ systems including the brain. Erythropoietin has antioxidant efffects and prevents neuronal damage in the animal model of ischemic brain injury. In this study, we aimed to investigate the effects of darbepoetin alpha, an analogue of ...
Shi Liang - - 2012
Noticeable differences between the vibrational (IR and Raman) spectra of neat H2O and D2O ice Ih are observed experimentally. Here we employ our theoretical mixed quantum/classical approach to investigate these differences. We find reasonable agreement between calculated and experimental line shapes at both high and low temperatures. From understanding the ...
Larson David J - - 2012
The ability to accurately reconstruct original spatial positions of field-evaporated ions emitted from a surface is fundamental to the success of atom probe tomography. As such, a clear understanding of the evolution of specimen shape and the resultant ions' trajectories during field evaporation plays an important role in improving reconstruction ...
Cupera Jakub - - 2012
The aim is to determine how well the rate parameter of the homogeneous model of dissolution can be estimated in dependency on the chosen times to measure the empirical data. The approach is based on the theory of Fisher information. We show that if the probability distribution of the measurement ...
Saboonchi Fredrik - - 2012
BACKGROUND: The syndrome of exhaustion is currently a medical diagnosis in Sweden. The description of the syndrome largely corresponds to the suggested core component of burnout, that is exhaustion. Karolinska Exhaustion Scale (KES) has been constructed to provide specific assessment of exhaustion in clinical and research settings. AIM: The purpose ...
Coutinho Eduardo - - 2012
There is strong evidence of shared acoustic profiles common to the expression of emotions in music and speech, yet relatively limited understanding of the specific psychoacoustic features involved. This study combined a controlled experiment and computational modelling to investigate the perceptual codes associated with the expression of emotion in the ...
Lee Eun Mi - - 2012
We conducted a phase II study of preoperative chemoradiation (CRT) with S-1 plus oxaliplatin in patients with locally advanced rectal cancer. The total radiotherapy dose was 50.4 Gy. Chemotherapy consisted of oxaliplatin 50 mg/m(2) on day 1, 8, 22 and 29, and S-1 80 mg/m(2) /day on day 1-14 and ...
Han R C RC Newcastle Eye Centre, Royal Victoria Infirmary, Newcastle upon Tyne, - - 2012
Visual symptoms in older people can be complex and inadequately explained by eye pathology alone. Psychological and neurodegenerative processes may manifest as complex visual symptoms, and thus some patients may be poorly served by a purely ophthalmic approach. We have developed a novel multidisciplinary clinic with input from neurology, ophthalmology, ...
Zhao Yang - - 2012
Graphene lite: A density of (2.1±0.3) mg cm(-3) , the lowest to date for a graphene framework architecture, is achieved by preparing an ultralight, N-doped, 3D graphene framework (see photo of a block of the material balancing on a dandelion). Its adsorption capacity for oils and organic solvents is much higher ...
Intartaglia Romuald - - 2012
Ultra small silicon nanoparticles (Si-NPs) with narrow size distribution are prepared in a one step process by UV picosecond laser ablation of silicon bulk in liquid. Characterization by electron microscopy and absorption spectroscopy proves Si-NPs generation with an average size of 2 nm resulting from an in situ photofragmentation effect. ...
Li X - - 2012
BACKGROUND AND OBJECTIVE: Adipocyte fatty acid-binding protein (A-FABP) is expressed in adipocytes, macrophages and microvascular endothelial cells, and it plays a central role in inflammation, atherosclerosis and metabolic responses. This pilot study investigated the effect of nonsurgical periodontal therapy on the serum levels of A-FABP in subjects with chronic periodontitis. ...
Hagemeister Fredrick B - - 2012
Observation until the development of symptoms, or 'watch and wait', has long been a proposed management technique for patients with indolent lymphomas. However, investigators have found that there may be differences in outcomes for various patient groups according to histopathology, clinical features of the disease, biologic factors as yet to ...
Pantic Igor - - 2012
Despite recent advances in hematopoietic tissue research, effects of aging on hematopoietic erythroid precursor (EP) cells are unclear. In this article we present results suggesting that chromatin textural entropy of EP cells in mouse spleen increases with age, while chromatin homogeneity decreases. The experiment was conducted on a total of ...
Saeheng Suwadee - - 2012
Background: To investigate the relationship between dermatopharmacokinetic (DPK) tape stripping from in vitro and in vivo using 1% terbinafine hydrochloride topical cream as the model formulation. Methodology: In vitro and in vivo tape strippings were conducted on separated pig ear skin used as a biological membrane for franz diffusion cell ...
Lee Hee Jin - - 2012
Colorectal micropapillary carcinoma has recently been reported as an aggressive variant of adenocarcinoma with a high incidence of lymph node metastasis, but has not been well investigated in terms of survival analysis. This study analyzed the clinicopathological characteristics, including survival data, of the patients with micropapillary carcinoma. We hypothesized that ...
Thuret Rodolphe - - 2012
What's known on the subject? and What does the study add? The European Association of Urology (EAU) guidelines recommend an inguinal lymph node dissection (ILND) in patients with T1G2-3 squamous cell carcinoma of the penis (SCCP). To date, only four series reported the rates of cancer-specific mortality (CSM) after primary ...
Yang Wenlong - - 2012
Brought to light: Ag(2) S-Ag hybrid nanotubes were synthesized by rapid microwave-assisted sulfidation of Ag(2) CO(3) nanorods. The relative amounts of Ag(2) S and Ag in the hybrid structure can be controlled easily by varying the concentration of the sulfur precursor. The optimized Ag(2) S-Ag hybrid structure has superior photocatalytic ...
Thomsen M - - 2012
We report how the three-dimensional structure of subcutaneous injections of soluble insulin can be visualized by x-ray computed tomography using an iodine based contrast agent. The injections investigated are performed ex vivo in porcine adipose tissue. Full tomography scans carried out at a laboratory x-ray source with a total acquisition ...
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