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Results 201 - 250 of 2501
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Seo Hwi Won - - 2012
This study was to compare the degree of cell-mediated immunity induced by three commercial Mycoplasma hyopneumoniae bacterins using interferon-γ (IFN-γ) measurements, lymphocyte stimulation assays, and delayed-type hypersensitivity tests. Serum IFN-γ levels were significantly elevated in all four vaccinated pig groups at 21 days post-vaccination (P<0.05). Lymphocytes isolated 21 days post-vaccination ...
Schmitt V - - 2012
Bismuth sodium titanate (Bi(0.5)Na(0.5))TiO(3) (BNT) is considered to be one of the most promising lead-free alternatives to piezoelectric lead zirconate titanate (PZT). However, the effect of dopants on the material has so far received little attention from an atomic point of view. In this study we investigated the effects of ...
Veit Michael - - 2012
Influenza virus is thought to assemble in raft-domains of the plasma membrane, but many of the conclusions were based on (controversial) Triton-extraction experiments. Here we review how sophisticated methods of fluorescence microscopy, such as FPALM, FRET and FRAP, contributed to our understanding of lipid domain association of the viral proteins ...
Sato Hirofumi - - 2012
The valence electronic states of thiophene (TP), 2-thiophenethiol (TT), 2,2'-bithiophene (BTP), and 2,2'-bithiophene-5-thiol (BTT) on Pt(111) were measured by ultraviolet photoemission spectroscopy (UPS) and metastable atom electron spectroscopy (MAES) to elucidate how the local electronic properties at the organic-metal interface are altered by the extent of π-conjugation and substituent effects. ...
- - 2012
The risks from physical inactivity for poor health are '...similar to the established risk factors of smoking and obesity.'
Kumar S S Department of Dermatology Channing Laboratory, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School Department of Epidemiology, Harvard School of Public Health, Boston, MA, - - 2013
To evaluate the associations between body mass index (BMI), weight change, waist circumference, hip circumference and risk of incident psoriasis. A prospective study of female nurses who were followed up over a 12-year period (1996-2008) in Nurses' Health Study, a cohort of 121,700 US women at the inception in 1976. ...
Zhang Wenjun - - 2012
Two new polyfluorenes with dipicolylamine (DPA) pendant, PF-TDPA and PF-HDPA, are designed and synthesized by pre- and post-functionalization, respectively. PF-TDPA with a rigid side chain shows a selective fluorescence quenching upon the addition of Cu(2+) in a mixture solution of tetrahydrofuran and 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid (HEPES) buffer. What is more, the ...
Möller Maaike Ip - - 2012
Abstract Objective: To assess the accuracy and reliability of cervico-portio (CP) length estimated using the Cervilenz™ compared to transvaginal ultrasound (TVU) cervical-length in women at high- and low-risk of spontaneous preterm birth (SPTB). Methods: Cervical-length was assessed longitudinally across gestation utilising CP-length measured with Cervilenz™ and TVU. Altman-Bland plots were ...
Liu Fuqiang - - 2013
Common variations in the gene with no-lysine kinase 1 (WNK1) are associated with hypertension, but because of gene-environment interaction, it is difficult to fully identify the genetic contribution of WNK1 gene polymorphism to blood pressure (BP) variability. The aim of this study was to identify the effect of common WNK1 ...
Müller Andreas - - 2012
AIMS: (1) To explore 'successful ageing' strategies in terms of selection, optimization and compensation in nursing; (2) To develop a scale that measures these strategies in nursing; (3) To investigate the association between these strategies in nursing and work ability of nurses and the moderating effects of age on this ...
Jin Xin - - 2012
Baohuoside I is an effective anti-cancer drug currently used for a variety of cancers in vitro. Unfortunately, baohuoside I has a very poor solubility in both water and in organic solvents. Besides that, it is subject to significant efflux. This work therefore aimed at evaluating the ability of mixed micelles ...
Ouyang Canbin - - 2012
One-dimensional nanostructures of the organic charge-transfer (CT) complex CuTNAP (copper 11,11,12,12-tetracyano-2,6-naphthoquinodimethane) were successfully synthesized by an organic vapor-solid phase reaction. The morphologies and field-emission properties of the CuTNAP nanostructures can be easily tuned by controlling the reaction conditions. It was observed that the field emission property is dependent on the ...
Rodgers Jonathan D - - 2012
We examined cognitive predictors of speech and articulation rate in 50 individuals with multiple sclerosis (MS) and 23 healthy controls. We measured speech and articulation rate from audio-recordings of participants reading aloud and talking extemporaneously on a topic of their choice (i.e., self-generated speech). Articulation rate was calculated for each ...
Middleton Christopher P - - 2012
A 454 sequencing snapshot was utilised to investigate the genome composition and nucleotide diversity of transposable elements for several Triticeae taxa, including T. aestivum, H. vulgare, H. spontaneum, S. cereale together with relatives of the A, B and D genome donors of wheat, T. urartu (A), Ae. speltoides (S), and ...
Tan Melvin X L - - 2012
Foam granulation technology is a new wet granulation approach for pharmaceutical formulations. This study evaluates the performance of foam and spray granulation in achieving uniform drug distribution using a model formulation. To observe wetting and nuclei formation, single drop/foam penetration experiments were performed on a static powder bed comprised of ...
Saeki Norihisa - - 2012
Gastric cancer (GC) is one of the major malignant diseases worldwide, especially in Asia, where Japan and Korea have the highest incidence in the world. GC is classified into intestinal and diffuse types. While the former is almost absolutely caused by Helicobacter pylori infection as initial insult, the latter seems ...
Bayoumi N H L NH Department of Ophthalmology, Faculty of Medicine, Alexandria University, 311 Horeya Avenue, Alexandria, Egypt. - - 2012
To study the additive value of deep sclerectomy to the procedure of combined trabeculotomy-trabeculectomy with mitomycin C (CTTM) for the treatment of primary congenital glaucoma. This study is a prospective, randomized case series. The study was conducted on 20 eyes of 20 children with primary congenital glaucoma presenting to the ...
Raghavan Badrinarayanan B Department of Dermatology, University of Würzburg, Josef-Schneider Straße 2, 97080 - - 2012
Development of contact allergy requires cooperation of adaptive and innate immunity. Ni(2+) stimulates innate immunity via TLR4/MD2, the bacterial LPS receptor. This likely involves receptor dimerization, but direct proof is pending and it is unclear if related haptens share this mechanism. We reveal Co(2+) as second metal stimulating TLR4 and ...
Miguel-Aliaga Irene - - 2012
Around 100 researchers gathered at the eighteenth EMBO Conference on 'The Molecular and Developmental Biology of Drosophila', which took place in Crete in June 2012. Whether deconstructing or integrating at the genetic, cellular or organ level, the talks highlighted the synergy of combining methods, approaches and disciplines in this increasingly ...
Manousaki Tereza - - 2012
The study of parallel evolution facilitates the discovery of common rules of diversification. Here, we examine the repeated evolution of thick lips in Midas cichlid fishes (the Amphilophus citrinellus species complex)-from two Great Lakes and two crater lakes in Nicaragua-to assess whether similar changes in ecology, phenotypic trophic traits and ...
Schicher N - - 2012
Background  Uveal melanoma is the most common intraocular neoplasm with a high tendency to metastasize predominantly to the liver. Prognostic parameters for progression and overall survival are not well defined. The aim of this study was to assess the value of pretherapeutic serum levels of C-reactive protein (CRP), lactate dehydrogenase, ...
Park Crystal L - - 2012
OBJECTIVE: We investigated predictors of emotional (worry) and cognitive (perceived risk) dimensions of fear of recurrence (FOR) and their relationships with psychological well-being in a sample of young and middle-aged adult cancer survivors. METHODS: Eligible participants were survivors between 18 and 55 years old and diagnosed from 1 to 3 years prior. ...
Brenner M K - - 2012
Cellular therapies for cancer are showing increasing efficacy but their introduction as a 'standard of care' for these disorders is hampered by technical, regulatory and financial concerns. This review identifies some of the major problems and suggests potential solutions.Cancer Gene Therapy advance online publication, 12 October 2012; doi:10.1038/cgt.2012.74.
Alam Anwar - - 2012
Abstract Addition of poly-dispersed acid functionalized Single-walled Carbon Nanotubes (AF-SWCNTs) significantly suppressed allo-immune cytotoxic T cell (CTL) response generated in a mixed lymphocyte reaction (MLR) between spleen cells from C57Bl/6 (H-2b) and BALB/c (H-2d) mice. AF-SWCNTs treatment also decreased the expression CD69 expression, enhanced apoptotic response in T cells and ...
Ohuchi Hideo - - 2012
Background: Maternal New York Heart Association (NYHA) class is associated with pregnancy outcome in women with congenital heart disease (WCHD), but objective predictive criteria of exercise capacity have not been established. Methods and Results: A total of 33 WCHD (age, 28±5 years; NYHA class, 1.3±0.6) who had undergone cardiopulmonary exercise testing (CPX) ...
Chime Salome Amarachi - - 2012
Objective: To formulate sustained-release diclofenac potassium-loaded solid lipid microparticles (SLMs) based on solidified reverse micellar solution (SRMS) and to evaluate the in vitro and in vivo properties. Methods: SRMS consisting of mixtures of Phospholipon® 90H and Softisan® 154 were used to formulate diclofenac potassium-loaded SLMs. Characterization based on the particle size and ...
Jiménez-Ruiz E - - 2012
SUMMARY Endogenous transplacental transmission (EnTT) of Neospora caninum is the most common route of infection in cattle and occurs as a consequence of a reactivation of N. caninum infection that may lead to abortion or to the birth of congenitally infected calves. The reactivation of N. caninum infection was studied ...
Valadas Jorge S - - 2012
In situations of hypoxia, glutamate excitotoxicity induces neuronal death. The release of extracellular adenosine is also triggered and is accompanied by an increase of the stress mediator, corticotrophin-releasing factor (CRF). Adenosine A(2A) receptors contribute to glutamate excitoxicity and their blockade is effective in stress-induced neuronal deficits, but the involvement of ...
Artini Marco - - 2012
AIMS: The purpose of this study was to evaluate the antimicrobial efficacy of five different proteases belonging to two different families on S. aureus and S. epidermidis strains. METHODS AND RESULTS: We used three serine proteases and two metalloproteases in single species biofilm formation assays and in human cell invasion ...
Bryant Daniel M - - 2012
To assess global and regional brain matter variations associated with XYY syndrome by comparison with Klinefelter syndrome and typical development. We used two conceptually distinct voxel-based magnetic resonance imaging methods to examine brain structure in young males with XYY syndrome: (1) volumetric comparison to assess global grey and white matter ...
Wehner Johannes W - - 2012
There is a wide range of immobilisation reactions to tether substrates to a variety of surfaces for array-based analysis. Most of these immobilisation strategies are specific for a particular surface and require an additional linker to be attached to the substrate or the surface. Furthermore, the analysis of functionalised surfaces ...
Eliseev Andrei A - - 2012
Best of both worlds: Electrochemical X-ray photolithography combines the advantages of X-ray photolithography with the versatility of electrochemical processing. A proof-of-concept was carried out by electrochemical deposition of nickel under coherent X-ray illumination guided through a lithographic mask with a 4 micrometer pitch, resulting in formation of a nickel grating.
Torres A - - 2012
Here is reported a disorder of sex development found in the Portuguese Lusitano horse breed. The complex genital phenotype included mammary glands, abdominal testes without epididymis, connected through oviducts to pelvic hypoplastic uterine horns and fused vulvar labia majora from which protruded ventrally a penis-like structure. This structure was presented ...
Stewart Beverly - - 2012
The formation of an active 16-electron ruthenium sec-alkoxide complex via loss of the CO ligand is an important step in the mechanism of the racemization of sec-alcohols by (η(5)-Ph(5)C(5))Ru(CO)(2)X ruthenium complexes with X = Cl and O(t)Bu. Here we show with accurate DFT calculations the potential energy profile of the ...
Bollag Gideon - - 2012
The identification of driver oncogenes has provided important targets for drugs that can change the landscape of cancer therapies. One such example is the BRAF oncogene, which is found in about half of all melanomas as well as several other cancers. As a druggable kinase, oncogenic BRAF has become a ...
Ting D S W DS The Australian E-Health Research Centre, Commonwealth Scientific Industrial Research Organization (CSIRO), Floreat, WA 6009, Australia. - - 2012
To evaluate the accuracy of different viewing monitors for image reading and grading of diabetic retinopathy (DR). Single-centre, experimental case series-evaluation of reading devices for DR screening. A total of 100 sets of three-field (optic disc, macula, and temporal views) colour retinal still images (50 normal and 50 with DR) ...
Scott Nicola N Guy's and St Thomas' NHS Foundation Trust, London, UK. - - 2013
Associations between sleep duration and disturbance in infancy and early childhood and attention deficit hyperactivity disorder diagnoses were investigated. Data from the Avon Longitudinal Study of Parents and Children, a population-based prospective longitudinal birth-cohort study of children born in 1991-1992 in South-West England, were employed. Eight thousand, one hundred and ...
Alves Hm - - 2012
This study aimed to evaluate various concentrations of egg yolk (5, 10, or 20%) in combination with different concentrations of glycerol (3% or 6%) added to a Tris-based extender on the post-thaw characteristics of sperm obtained from Tayassu tajacu. For this purpose, semen from 10 sexually male mature collared peccaries ...
Thompson J M - - 2012
AIMS: To investigate the presence of methicillin-resistant Staphylococcus aureus (MRSA) in untreated hospital wastewaters (UHWW), their transmission into the receiving sewage treatment plant (STP) and survival through the STP treatment. METHODS AND RESULTS: Over 8 consecutive weeks of sampling we isolated 224 S. aureus strains from UHWW-1, UHWW-2 and its ...
Mughal M Akhlaq - - 2012
Hydralazine hydrochloride is an antihypertensive used alone or in combination with isosorbide nitrate for the treatment of congestive heart failure. Since control of blood pressure should be continuous, sustained release delivery of this drug is considered therapeutically beneficial. Core beads for oral administration of this drug were prepared by extrusion-spheronization. ...
Liu Shujuan S Key Laboratory for Organic Electronics & Information Displays (KLOEID), Nanjing University of Posts & Telecommunications (NUPT), Nanjing 210046, P R - - 2013
Homocysteine (Hcy) and cysteine (Cys) are two important kinds of amino acids in human bodies. Herein, we synthesized an iridium(III) complex-functionalized poly(N-isopropylacrylamide) and its hydrogel, which could be used as the excellent phosphorescent bioprobe for sensing Hcy and Cys. Their detection can be realized in aqueous system through the variations ...
Whyte Sophie - - 2012
The National Institute for Health and Clinical Excellence (NICE) invited the manufacturer of bevacizumab (Roche Products) to submit evidence for the clinical and cost effectiveness of this drug for the treatment of patients with metastatic colorectal cancer (mCRC), as part of the Institute's Single Technology Appraisal (STA) process. The School ...
Engel Philipp P Department of Ecology and Evolutionary Biology, Yale University, New Haven, CT, USA. - - 2013
The honey bee, Apis mellifera, harbors a characteristic gut microbiota composed of only a few species which seem to be specific to social bees. The maintenance of this stable and distinct microbial community depends on the social lifestyle of these insects. As in other animals, the bacteria in the gut ...
Barr-Anderson D J DJ Arnold School of Public Health, University of South Carolina, Columbia, SC 29208, USA. - - 2013
Obesity interventions that involve family members may be effective with racial/ethnic minority youth. This review assessed the nature and effectiveness of family involvement in obesity interventions among African-American girls aged 5-18 years, a population group with high rates of obesity. Twenty-six databases were searched between January 2011 and March 2012, ...
Ramseier C A - - 2012
Background and aim Dental professionals need adequate education in tobacco use prevention and cessation skills. The aim of this study was to identify the level of integration of tobacco education in undergraduate curricula of European dental schools.Method In 2009, a total of 197 European dental schools were identified through web-based ...
Ronikier M - - 2012
The arctic-alpine Ranunculus glacialis s. l. is distributed in high-mountain ranges of temperate Europe and in the North, where it displays an extreme disjunction between the North Atlantic Arctic and Beringia. Based on comprehensive sampling and employing plastid and nuclear marker systems, we (i) test whether the European/Beringian disjunction correlates ...
Li Zifu - - 2012
The formation of hierarchical porous protein scaffolds from oil-in-water (o/w) high internal phase emulsions (HIPEs) stabilized by bovine serum albumin (BSA) protein nanoparticles (Pickering HIPE) is reported. The route consists of three principal steps. First, a stable o/w HIPE stabilized by BSA protein nanoparticles is formulated. Next, crosslinking the dispersed ...
Mehretie Solomon - - 2012
An iron(iii) doped zeolite modified glassy carbon electrode was constructed for the determination of pyridine-2-aldoxime methochloride. X-ray diffraction and chemical analysis were utilized to determine the optimum pH and chemical content for doping zeolite. Cyclic voltammetry was used to characterize the modified electrode and study the kinetics of the acid ...
Priddis Holly - - 2012
AIMS: This article presents a meta-ethnographic synthesis of studies on women's experiences of sustaining a third or fourth degree tear during childbirth. BACKGROUND: It has been reported that for women who sustain third or fourth degree perineal tears (severe perineal trauma) some may experience extensive physical and psychological outcomes. DESIGN: ...
Alvarez M - - 2012
The main goal of this work was to develop a methodology for the computed analysis of American College of Radiology (ACR) mammographic phantom images, to be used in a quality control (QC) program of mammographic services. Discrete wavelet transform processing was applied to enhance the quality of images from the ...
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