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Results 501 - 550 of 2497
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Viana Priscilla - - 2012
Gas ebullition-facilitated transport of metals and polycyclic aromatic hydrocarbons (PAHs) from the sediment to the water column was investigated in 14 urban waterway locations. Gas ebullition ranged from 2-450 mmol m-2 d-1 with a mean (±1 SEM) of 140±90 mmol m-2 d-1 over four seasons at the field sites and ...
Olmos Carmen - - 2012
AimsThe prognosis of patients with infective endocarditis (IE) remains poor despite the great advances in the last decades. One of the factors closely related to mortality is the development of septic shock (SS). The aim of our study was to describe the profile of patients with IE complicated with SS, ...
Kobayashi Leo - - 2012
BACKGROUND AND OBJECTIVES: Medical simulation and human factors engineering (HFE) may help investigate and improve clinical telemetry systems. Investigators sought to (1) determine the baseline performance characteristics of an Emergency Department (ED) telemetry system implementation at detecting simulated arrhythmias and (2) improve system performance through HFE-based intervention. METHODS: The prospective ...
Suh Dong-Hye - - 2012
Abstract Background: Infraorbital laxity is a common problem that increases with age. Blepharoplasty with lipectomy is a very commonly performed surgical procedure to treat this problem; however, it is invasive and is associated with the potential for reemergence. Therefore, young patients may prefer a non-surgical procedure to a surgical procedure. ...
Cui Yong - - 2012
INTRODUCTION: The presence of cigarette-related cues has been associated with smoking relapse. These cues are believed to activate brain mechanisms underlying emotion, attention, and memory. Electroencephalography (EEG) alpha desynchronization (i.e., reduction in alpha power) has been suggested to index the engagement of these mechanisms. Analyzing EEG alpha desynchronization in response ...
Medina-Bravo Patricia - - 2012
BACKGROUND: Recent evidence suggests that high-density lipoprotein (HDL) physicochemical characteristics and functional capacity may be more important that HDL-C levels in predicting coronary heart disease. There is little data regarding HDL subclasses distribution in youth with type 1 diabetes. OBJECTIVE: To assess the relationships between glycemic control and HDL subclasses ...
Kaufmann Anke - - 2012
G-protein coupled designer receptors that are specifically activated by designer drugs have been developed. Here, we have analyzed the regulation of gene transcription following activation of Gα(q) -coupled designer receptor (Rα(q) ). Stimulation of human embryonic kidney (HEK) 293 cells expressing Rα(q) with clozapine-N-oxide (CNO), a pharmacologically inert compound, induced ...
Ayuk Sandra M - - 2012
Abstract Background: Collagen type I (Col-I) is a major component of the extracellular matrix and is important in wound healing processes. Several studies have shown that low-intensity laser irradiation (LILI) biostimulates Col-I synthesis both in vitro and in vivo. This study aimed to determine if LILI affects collagen production and ...
Grigoriev Pavel - - 2012
We report analyses of regional trends in overall and cause-specific mortality in Belarus for the period 1990-2007. We explore the respective spatial patterns and attempt to determine the factors responsible for the regional mortality variation. The results show that inter-regional mortality differentials tend to rise, mainly because of the growing ...
Chen Miao - - 2012
Chromium mononitride (CrN) exhibits interesting magnetic, structural, and electronic properties for technological applications. Experimental reports on these properties are often inconsistent owing to differences in the degree of nonstoichiometry in CrN(x) . To date, the preparation of bulk and stoichiometric CrN has been challenging; most products are in the form ...
Chen Hao - - 2012
Using Pt3Fe nanoparticles as an example, a surfactant-free Np-KCl matrix method (Np stands for nanoparticle) is developed for the synthesis of nanoparticles with controlled size and structure. In this method, the Np-KCl assembly is formed in a one-pot reduction in THF at room temperature. KCl is an insoluble by-product of ...
Lee Hyung Min - - 2012
Abstract BACKGROUND: Although ablative fractional laser for the facial photodamaged skin was effective and safe, there have been only limited reports regarding the efficacy and safety of fractional Er:YAG laser treatments for photodamaged facial skin in Asians. OBJECTIVE: Our objective was to assess the efficacy and safety of the Er:YAG ...
Santini A - - 2012
A large database of invasive forest pathogens (IFPs) was developed to investigate the patterns and determinants of invasion in Europe. Detailed taxonomic and biological information on the invasive species was combined with country-specific data on land use, climate, and the time since invasion to identify the determinants of invasiveness, and ...
Jiao Yong - - 2012
Seeing in many colors: Confocal images acquired using fluorescently labeled amyloid β-peptide revealed its efficient internalization by endocytosis into endosomes/lysosomes of human neuronal cells with a small portion reaching mitochondria, inducing marked cellular and mitochondrial reactive oxygen species production.
Kushch L A - - 2012
A new high symmetry Mn(12) oxocarboxylate cluster [Mn(12)O(12)(CN-o-C(6)H(4)CO(2))(12)(CH(3)CO(2))(4)(H(2)O)(4)]·8CH(2)Cl(2) () with mixed carboxylate ligands is reported. It was synthesized by the standard carboxylate substitution method. crystallizes in the tetragonal space group I4(1)/a. Complex contains a [Mn(12)O(12)] core with eight CN-o-C(6)H(4)CO(2) ligands in the axial positions, four CH(3)CO(2) and four CN-o-C(6)H(4)CO(2) in ...
Perreault Michel - - 2012
This study assesses the Urban Breakaway Project, a collaborative project offering a structured vacation in the countryside of the province of Quebec intended for homeless (or street) youths. The objective of this study was to document participants' perspectives regarding this project by examining their satisfaction, intention to change following their ...
Li Qing - - 2012
Epithelial-mesenchymal transition (EMT) is a key cellular event in the early stage of tubulointerstitial fibrosis (TIF). Monocyte infiltration plays an important role in the progression of TIF. We have previously demonstrated that monocytes can directly induce HK-2 cell transition by direct contact. Dexamethasone, an important anti-inflammatory and immunosuppressant agent, has ...
Lodato Rossella - - 2012
In occupational environments, an increasing number of electromagnetic sources emitting complex magnetic field waveforms in the range of intermediate frequencies is present, requiring an accurate exposure risk assessment with both in vitro and in vivo experiments. In this article, an in vitro exposure system able to generate complex magnetic flux ...
Sudhyadhom Atchar - - 2012
PURPOSE: To employ and compare probabilistic diffusion tractography (PDT) for the explicit localization of connections from the thalamus to somatosensory cortex (S1) and primary motor cortex (M1) / supplementary motor area (SMA) with microelectrode electrophysiology in patients undergoing deep brain stimulation (DBS) surgery. MATERIALS AND METHODS: These tractography-derived connections were ...
Kaewkhaw Rossukon - - 2012
We describe a simple, rapid and highly selective protocol for the primary culture of Schwann cells in vitro from freshly dissociated adult rat nerve. The protocol is based on a selective culture medium comprising both mitogens (forskolin and optionally N2 supplement plus bovine pituitary extract), to stimulate growth of Schwann ...
Fukaya Chikashi - - 2012
OBJECTIVES: Intracranial hemorrhage is a crucial complication of deep brain stimulation (DBS) surgery. The bleeding caused by mechanical tissue injury due to microelectrode and/or DBS electrode lead insertion has been well studied. However, hemorrhage caused by a congenital underlying disease such as vascular malformation has not been examined carefully. MATERIALS ...
Choi Jong-Cheol - - 2012
A new method for the high-throughput study of cell spreading dynamics is devised by multi-step microscopy projection photolithography based on a cell-friendly photoresist. By releasing a large number of rounded cells in single cell arrays and monitoring their spreading dynamics by interference reflection microscopy, a large number of cell spreading ...
Fonseca Nuno A - - 2012
MOTIVATION: A ubiquitous and fundamental step in high-throughput sequencing analysis is the alignment (mapping) of the generated reads to a reference sequence. To accomplish this task numerous software tools have been proposed. Determining the mappers that are most suitable for a specific application is not trivial. RESULTS: This survey focuses ...
Kaplan Kursat Ali - - 2012
  Gastroprotective effects of α-lipoic acid (ALA) against oxidative gastric damage induced by indomethacin (IND) have been investigated. All doses (50, 75, 100, 150, 200, and 300 mg/kg body weight) of ALA reduced the ulcer index with 88.2% to 96.1% inhibition ratio. In biochemical analyses of stomach tissues, ALA administration ...
Sherwinter Danny A - - 2012
The rigid sigmoidoscope is an important tool in a surgeon's armamentarium, yet it has remained essentially unchanged despite poor imaging and the inability to project or record the images. Herein we report our initial experience with a novel introducer built from readily available operating room supplies and designed to convert ...
Byrne Sahara - - 2012
One reason that tobacco-sponsored smoking cessation ads are less effective than those sponsored by public health agencies may be that the persuasive arguments in tobacco-sponsored ads are inherently weaker than arguments made in public health ads. An alternate explanation is that sponsorship disclosure on the face of the ad activates ...
Wills B P D - - 2012
Metacarpal shaft fractures are common injuries that frequently unite with some shortening of the metacarpal. The aim of this study was to determine the effect of metacarpal shortening on digital flexion force. The index metacarpal of six cadaveric upper limbs was incrementally shortened. The flexion force produced at the end ...
Vanneste Sven - - 2012
A double-cone coil with large angled windings has been developed to modulate deeper brain areas such as the anterior cingulate cortex (ACC). Abnormal resting state activity in the pregenual ACC (pgACC), dorsal ACC (dACC) and subgenual ACC (sgACC) has been observed in depression. A patient with medication resistant chronic depression ...
Budec Mirela - - 2012
AIMS: We showed previously that the acute effect of ethanol on intestinal immunoglobulin A (IgA) expression might be mediated by endogenous nitric oxide (NO). To extend these findings, this study was designed to investigate a possible role of neuronal NO synthase (nNOS) in the observed phenomenon, using 7-nitroindazole (7-NI), a ...
Mazziotti Silvio - - 2012
MR of the small bowel is a useful technique for the evaluation of both intraluminal and extraluminal pathologic involvement of the small bowel in patients with Crohn's disease. Crohn's disease is associated with a range of extraintestinal complications that sometimes may be the initial presenting symptoms. Some of these extraintestinal ...
de la Fuente Marta González - - 2012
AIMS: β-adrenergic stimulation has profound influence in the genesis and maintenance of atrial fibrillation (AF). However, the effects of β-adrenoceptors stimulation on repolarizing currents and action potential (AP) characteristics in human atrial myocytes from left (LAA) and right atrial appendages (RAA) obtained from sinus rhythm (SR) and chronic AF (CAF) ...
Zeng Xian-Chun - - 2012
ABBA was reported to be an actin dynamics regulator. However, the molecular mechanism of action of ABBA is still totally obscure. Here we show that ABBA is ubiquitously expressed in all the examined cultured cells. We found that expression of ABBA in NIH3T3 cells promotes cell spreading. ABBA binds to ...
Cosconati Sandro - - 2012
Targeting of DNA secondary structures, such as G-quadruplexes, is now considered an appealing opportunity for drug intervention in anticancer therapy. So far, efforts made in the discovery of chemotypes able to target G-quadruplexes mainly succeeded in the identification of a number of polyaromatic compounds featuring end-stacking binding properties. Against this ...
Chan Tracey Evans - - 2012
Developments in medical technology, healthcare delivery, and commercial interests in medicine have increased both the potential for conflicts of interest on the part of physicians, and doubts over the sufficiency of patient autonomy as a justification for administering innovative therapy. The legal and regulatory treatment of innovative therapy is therefore ...
Zhang Lei - - 2012
Fe2O3 microboxes with hierarchically structured shells have been synthesized by simply annealing Prussian blue (PB) microcubes. By utilizing simultaneous oxidative decomposition of PB microcubes and crystal growth of iron oxide shells, we have demonstrated a scalable synthesis of anisotropic hollow structures with various shell architectures. When evaluated as an anode ...
Mei Qiang - - 2012
ABSTRACT: BACKGROUND: MTHFR 677C>T polymorphism is a genetic alteration in an enzyme involved in folate metabolism, but its effect on host susceptibility to cervical cancer is still uncertain. The aim of this study was to investigate the association between MTHFR 677C>T polymorphism and cervical cancer by performing a meta-analysis. METHODS: ...
Kallio Johanna - - 2012
Quercetin is a natural flavonoid possessing a number of health beneficial effects. Its bioactivity is restricted by low solubility and sensitivity to oxidative degradation, factors that are often ignored in laboratory studies. We studied the antimicrobial effects of quercetin on Staphylococcus aureus, Escherichia coli and Lactobacillus plantarum at concentrations at ...
Rebelo A - - 2012
Anthropometric characteristics, physical fitness and technical skills of under-19 (U19) soccer players were compared by competitive level (elite, n=95; non-elite, n=85) and playing position (goalkeeper, central defender, fullback, midfield, forward). Fitness tests included 5- and 30-m sprints, agility, squat jump (SJ) and countermovement jump (CMJ), strength and Yo-Yo intermittent endurance ...
Blades Megan L - - 2012
Further insight towards the complex association and dissociation events of macromolecules requires the development of a spectroscopic technique that can track individual components, or building blocks of these macromolecules, and the complexes which they form, in real time. 3-color fluorescence cross-correlation spectroscopy (3C-FCCS) has been shown to track assemblies of ...
Francés Daniel E A - - 2012
Increased expression of COX-2 has been linked to inflammation and carcinogenesis. Constitutive expression of COX-2 protects hepatocytes from several pro-apoptotic stimuli. Increased hepatic apoptosis has been observed in experimental models of diabetes. Our present aim was to analyze the role of COX-2 as a regulator of apoptosis in diabetic mouse ...
Lewis Melissa A - - 2012
Research has demonstrated ambiguity about the definition of hooking up among college students. The current research examined whether there were multiple definitions of hooking up among college students and how different definitions might be associated with the participant's own hooking up behavior and normative perceptions of peer hooking up behavior. ...
Stasiak Karolina - - 2012
Background: Outcome measurement in child and adolescent mental health services in New Zealand became mandatory in 2005 and little is known about how this is perceived by service users.Aims: This study aimed to ascertain what service users think about routine outcome measurement in child and adolescent mental health services.Method: Nine ...
Chang Victoria C - - 2012
Background. The influence of endoscopic video camera (VC) image quality on surgical performance has not been studied. Flexible endoscopes are used as substitutes for laparoscopes in natural orifice translumenal endoscopic surgery (NOTES), but their optics are originally designed for intralumenal use. Manipulable wired or wireless independent VCs might offer advantages ...
Müssig K - - 2012
Purpose: Though increased thyroid perfusion assessed by colour-coded Doppler ultrasound (CDUS) is characteristic of Graves' disease (GD), sometimes perfusion assessment by CDUS is not possible. In these cases, arterial spin labelling (ASL), a novel magnetic resonance imaging (MRI) technique allowing non-invasive thyroid perfusion quantification, may have additional diagnostic value. We ...
Shukla Awadhesh Kumar - - 2012
Over the past few years biodegradation of trichloroethylene (TCE) using different microorganisms has been investigated by several researchers. In this review article, an attempt has been made to present a critical summary of the recent results related to two major processes - reductive dechlorination and aerobic co-metabolism used for TCE ...
Forrester Mb - - 2012
1,3-Dimethylamylamine (DMAA) is an ingredient in a number of weight loss and exercise performance enhancing products. However, information on the safety of DMAA-containing products is limited. Exposures to DMAA-containing products reported to Texas poison centers during 2010-2011 were identified and selected factors were examined. A total of 56 exposures were ...
Drechsler Astrid - - 2012
AFM force measurements have been performed to study the influence of the pH value and salt concentration on the interactions between poly(2-vinyl pyridine) brushes and microsized silica spheres with focus on attractive and adhesion forces. It was found that the interaction was composed of a repulsive component reflecting the conformation ...
Ieong Ka-Weng - - 2012
Translations with unnatural amino acids (AAs) are generally inefficient and kinetic studies of their incorporations from tRNAs are few. Here, the incorporations of small and large, non-N-alkylated, unnatural L-AAs into dipeptides were compared with natural amino acids using quench-flow techniques. Surprisingly, all incorporations occurred in two phases: fast then slow, ...
Burgess Robert M - - 2012
Globally, estimated costs to manage (i.e., remediate and monitor) contaminated sediments are in the billions of U.S. dollars. Biologically based approaches for assessing the contaminated sediments which pose the greatest ecological risk range from toxicity testing to benthic community analysis. In addition, chemically based sediment quality guidelines (SQGs) provide a ...
Thakkar Santosh V - - 2012
A molecular understanding of excipient effects on the interrelationship(s) between dynamics and conformational stability of proteins, such as monoclonal antibodies (mAbs), can be important for their pharmaceutical development. The current study examines stabilizing and destabilizing effects of excipients on the conformational stability and local dynamics of distinct solvent-exposed regions within ...
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