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Dixon Mike J MJ University of Waterloo, Waterloo, - - 2013
Near-misses in slot machines resemble jackpot wins but fall just short. Previous research has demonstrated that near-misses are behaviorally reinforcing despite the absence of monetary reward. We assessed the hedonic properties of near-misses by measuring the time between outcome delivery and the initiation of the next spin-the post-reinforcement pause (PRP) ...
Rockloff Matthew J MJ Institute for Health and Social Science Research, Central Queensland University, Bundaberg, QLD, 4670, Australia, - - 2013
This paper reviews literature on how jackpots influence Electronic Gaming Machine (EGM) gambling behaviour. Most of the available evidence addresses the motivational effect of the mere presence of EGM jackpots on play, as actual wins are relatively rare for individual gamblers. The review identifies a distinction between rational, biased and ...
Spina Juan Carlos JC Department of Radiology, Hospital Italiano, Universidad de Buenos Aires, Gascón 450, Buenos Aires, - - 2013
Transcatheter arterial chemoembolization with drug-eluting beads (TACE-DC-beads) is a new local treatment for primary or metastatic liver tumors. Despite technical efforts to achieve highly selective embolization of the tumor-supplying vessels, small, or large insults to the non-tumorous parenchyma are inevitably induced by the embolic materials or procedure itself. Parenchymal changes ...
Maguiña Jorge L JL Unit of Health, Sexuality and Human Development, Cayetano Heredia Peruvian University, Lima, Peru. - - 2013
This article presents data about the relationship between alcohol consumption prior to sex and unprotected sex and the prevalence of at least one sexually transmitted infection (STI) including HIV among socially marginalized men in three coastal Peruvians cities. During an epidemiological survey with 2,146 men, we assessed their STI prevalence, ...
Rosell Karolina K Hidrosis Clinic, Sophiahemmet, Stockholm, - - 2013
Hyperhidrosis is a common disorder that may have a severe impact on quality of life. The aim of this study was to investigate the clinical effect of two novel botulinum toxins, Xeomin®, a type A botulinum toxin, and Neuro-bloc®, a type B botulinum toxin, in the treatment of axillary and ...
Dong M - - 2013
Traditionally, oestrogens were considered to be protective for the cardiovascular system for premenopausal women. Therefore, we conducted a retrospective case-control study to examine the association between endogenous oestrogens and acute myocardial infarction (AMI) risk among postmenopausal women. A case-control study was performed among 30 primary AMI patients and 60 control ...
Powers Daniel A - - 2013
I reexamine the epidemiological paradox of lower overall infant mortality rates in the Mexican-origin population relative to U.S.-born non-Hispanic whites using the 1995-2002 U.S. NCHS linked cohort birth-infant death files. A comparison of infant mortality rates among U.S.-born non-Hispanic white and Mexican-origin mothers by maternal age reveals an infant survival ...
Crawford Natalie D ND Department of Epidemiology, Center for Social Epidemiology and Population Health, School of Public Health, University of Michigan, Ann Arbor, MI 48109, USA. - - 2013
Social discrimination may isolate drug users into higher risk relationships, particularly in disadvantaged neighborhood environments where drug trade occurs. We used negative binomial regression accounting for clustering of individuals within their recruitment neighborhood to investigate the relationship between high-risk drug ties with various forms of social discrimination, neighborhood minority composition, ...
Kessler Jeff J Kaiser Los Angeles Medical Center, 4760 Sunset Boulevard, Los Angeles, CA 90027, USA. - - 2013
A number of studies have found an increased risk of lower extremity injuries in obese patients. Most studies, however, are unable to provide stable population-based estimates based on the degree of obesity and few assess the risk pertaining to more detailed fracture location in the lower extremities. We therefore investigated ...
Galeotti Nicoletta N Department of Preclinical and Clinical Pharmacology, Viale G. Pieraccini 6, Florence, 50139, Italy. - - 2013
There is convincing evidence that nitric oxide (NO) may be a causative factor in the pathogenesis of migraine. We investigated the consequences of NO donors' administration on meningeal processes related to the development of migraine pain in an animal model of meningeal nociception. The administration in mice of the NO ...
Shea Kevin G KG St Luke's Sports Medicine, St Luke's Children's Hospital, and Department of Biological Sciences, Boise State University, 109 East Bannock Street, Boise, ID 83712, - - 2013
Although many etiological theories have been proposed for osteochondritis dissecans (OCD), its etiology remains unclear. Histological analysis of the articular cartilage and subchondral bone tissues of OCD lesions can provide useful information about the cellular changes and progression of OCD. Previous research is predominantly comprised of retrospective clinical studies from ...
Lee Rushyuan J RJ Department of Orthopaedic Surgery, The Johns Hopkins University, Baltimore, MD, - - 2013
Obesity is a risk factor for various orthopaedic diseases, including fractures. Obesity's influence on circulating hormones and cytokines and bone mineralization ultimately influences the body's osteogenic response and bone mineralization, potentially increasing the risk of fracture and impacting fracture healing. Does obesity delay fracture recovery in overweight or obese children ...
Lang Delia L DL Department of Behavioral Sciences and Health Education, Rollins School of Public Health, Emory University, 1518 Clifton Road, Room 548, Atlanta, GA, USA. - - 2013
The purpose of this study was to examine the prevalence of pregnancy as well as multi-level factors (i.e., individual, family, and environment) associated with history of pregnancy among a sample of urban adolescent women seeking psychological services. Data were collected from a total of 264 sexually active, 13-18-year-old, adolescent women ...
Petroll W Matthew WM Department of Ophthalmology, University of Texas Southwestern Medical Center, Dallas, TX, USA. - - 2013
The purpose of this study was to develop and test hardware and software modifications to allow quantitative full-thickness corneal imaging using the Heidelberg Retina Tomograph (HRT) Rostock Corneal Module. A personal computer-controlled motor drive with positional feedback was integrated into the system to allow automated focusing through the entire cornea. ...
Norman James J JJ School of Chemical and Biomolecular Engineering, Georgia Institute of Technology, Atlanta, GA 30332, - - 2013
Limitations with standard intradermal injections have created a clinical need for an alternative, low-cost injection device. In this study, we designed a hollow metal microneedle for reliable intradermal injection and developed a high-throughput micromolding process to produce metal microneedles with complex geometries. To fabricate the microneedles, we laser-ablated a 70 ...
Miller Amanda C AC Vanderbilt University, 110 Magnolia Circle, Nashville, TN 37203, USA. - - 2013
We examined reading comprehension in children with ADHD by assessing their ability to build a coherent mental representation that allows them to recall central and peripheral information. We compared children with ADHD (mean age 9.78) to word reading-matched controls (mean age 9.89) on their ability to retell a passage. We ...
DeVolder Ian I Department of Psychiatry, University of Iowa Carver College of Medicine, Iowa City, IA, USA. - - 2013
Isolated cleft lip and/or palate (ICLP) is one of the most common congenital birth defects in the USA, affecting roughly 1 in 600 births annually. Along with the facial deformity, this population has been found to have abnormal neurodevelopment and gross structural abnormalities in the brain, particularly within the cerebellum. ...
Healey John H - - 2013
Compliant, self-adjusting compression technology is a novel approach for durable prosthetic fixation of the knee. However, the long-term survival of these constructs is unknown. We therefore determined the survival of the Compress prosthesis (Biomet Inc, Warsaw, IN, USA) at 5 and 10 actuarial years and identified the failure modes for ...
Stiefel Friedrich F Lausanne University Hospital, Lausanne, Switzerland. - - 2013
This study assessed medical students' perception of individual vs. group training in breaking bad news (BBN) and explored training needs in BBN. Master-level students (N = 124) were randomised to group training (GT)-where only one or two students per group conducted a simulated patient (SP) interview, which was discussed collectively with the ...
Ueda Takafumi T Osaka University Orthopaedic Oncology Group, Osaka, Japan, - - 2013
Limb-salvage reconstruction for periacetabular malignant tumors is one of the most challenging problems in orthopaedic oncology. Reconstructive options include resection arthroplasty, endoprosthesis, allograft, recycled autobone graft, arthrodesis, and pseudarthrosis. However, no standard procedure exists because of rarity and clinical variability of the disease. We previously developed a megaprosthetic system with ...
Wang Xiao B XB Department of Pediatrics, David Geffen School of Medicine at UCLA, Los Angeles, CA, - - 2013
This project examined sexual behavior and STI prevalence among HIV-infected individuals in South China. Adult HIV-infected outpatients in Guangzhou, Guangdong Province, China completed a self-administered survey about behaviors and antiretroviral treatment. Participants were screened for syphilis, gonorrhea, and chlamydia. Univariate and multivariate relationships with any STI were calculated using logistic ...
Erwin Deborah O DO Roswell Park Cancer Institute, Cancer Prevention and Population Sciences, Buffalo, NY, USA. - - 2013
Reported barriers to participation in biospecimen banking include unwillingness to undergo blood-draw procedures and concerns about confidentiality breaches, privacy, and discrimination. The study identified key factors and influential perspectives to address these barriers and inform methods to improve recruitment and research participation among racially diverse community. A mixed-methods, community-based participatory ...
Suzuki Hideo H Department of Psychiatry, Washington University School of Medicine, Saint Louis, MO 63110, USA. - - 2013
Although hippocampal atrophy and altered functional brain responses to emotional stimuli have been found in major depressive disorder (MDD), the relationship between the two is not yet well understood. The present study focused on children with and without a history of preschool onset MDD (PO-MDD) and directly examined the relations ...
Compton Rebecca J RJ Department of Psychology, Haverford College, Haverford, PA 19041, USA. - - 2013
In this study, we tested the relationship between error-related signals of cognitive control and cortisol reactivity, investigating the hypothesis of common systems for cognitive and emotional self-regulation. Eighty-three participants completed a Stroop task while electroencephalography (EEG) was recorded. Three error-related indices were derived from the EEG: the error-related negativity (ERN), ...
Hershey Linda A - - 2013
Most primary headaches in the elderly are similar to those in younger patients (tension, migraine, and cluster), but there are some differences, such as late-life migraine accompaniments and hypnic headaches. Although migraine in younger persons usually presents with headache, migraine in older persons may initially appear with visual or sensory ...
Manganiello Marc - - 2013
Understanding the role that urologic disease plays within central Haiti could lead to the development of sustainable and regionally appropriate urologic care. We aim to document the prevalence of urologic surgical disease presenting for treatment in central Haiti. The present study is based on a retrospective review of surgical case ...
Gorbach Pamina M PM Department of Epidemiology, University of California, Los Angeles, 90095-1772, USA. - - 2013
In a microbicide safety and effectiveness trial (HPTN 035) in Malawi, 585 women completed the same questionnaire through a face-to-face interview (FTFI) and an audio computer-assisted self-interview (ACASI). Concordance between FTFI and ACASI responses ranged from 72.0 % for frequency of sex in the past week to 95.2 % for ...
Ginnetti John G JG University of Utah, 590 Wakara Way, Salt Lake City, UT 84108, - - 2013
The indication for hip arthrotomy accompanied by intraarticular work during periacetabular osteotomy (PAO) has not been precisely defined. To validate a role for routine hip arthrotomy accompanied by intraarticular work, frequent intraarticular pathology must exist, and the adjunct procedures must not be associated with inferior relief of pain, reduced function, ...
Reiner Bruce I BI Department of Radiology, Veterans Affairs Maryland Healthcare System, Baltimore, MD 21201, USA. - - 2013
While occupational stress and fatigue have been well described throughout medicine, the radiology community is particularly susceptible due to declining reimbursements, heightened demands for service deliverables, and increasing exam volume and complexity. The resulting occupational stress can be variable in nature and dependent upon a number of intrinsic and extrinsic ...
Cardinal J S JS University of Pittsburgh Medical Center, Liver Cancer Center, 3459 Fifth Avenue, Pittsburgh, PA 15213, - - 2013
Laparoscopic liver resections are being performed with increasing frequency, with several groups having reported minimally invasive approaches for major anatomic hepatic resections. Some surgeons favor a pure laparoscopic approach, while others prefer a hand-assisted approach for major laparoscopic liver resections. There are clear advantages and disadvantages to a hand-assisted technique. ...
van der Straten Ariane A Women's Global Health Imperative, RTI International, San Francisco, CA 94104, USA. - - 2013
The Wisebag™, a lunchbag-style container with an electronic events-monitoring system, was designed as a real-time indirect objective measure of microbicide gel use. Due to cost, alternative functionalities (i.e. use of offline and dummy versions) were explored. We conducted a three-arm, double-blinded pilot study among 50 HIV-negative women in Durban, South ...
Kelly Cheryl M CM Beth-el College of Nursing and Health Sciences, University of Colorado, 1420 Austin Bluffs Parkway, Colorado Springs, CO 80904, USA. - - 2013
Observational field audits are recommended for public health research to collect data on built environment characteristics. A reliable, standardized alternative to field audits that uses publicly available information could provide the ability to efficiently compare results across different study sites and time. This study aimed to assess inter-rater reliability of ...
Vieira É L M ÉL Department of Biochemistry and Immunology, Biological Sciences Institute, Universidade Federal de Minas Gerais, Belo Horizonte, MG, - - 2013
Leishmaniasis is an important tropical disease composed of several clinical forms that adversely affect millions of people globally. Critical cells involved in the host-Leishmania interaction are monocytes and macrophages, which act to protect against infections due to their ability to both control intracellular infections and regulate the subsequent adaptive immune ...
Abood Gerard J GJ Division of Surgical Oncology, Department of Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA, - - 2013
Minimally invasive liver surgery has recently undergone an explosion in reported worldwide experience. Given its comparable outcomes to its open counterpart, high-volume centers are utilizing minimal access liver surgery more frequently under well-defined criteria. The recent introduction of robot-assisted surgery has further revolutionized the field of minimally invasive surgery and ...
Commins Scott P SP Department of Internal Medicine & Pediatrics, Division of Allergy and Immunology, University of Virginia Health System, Charlottesville, VA 22908, USA. - - 2013
Anaphylaxis is a severe allergic reaction that can be rapidly progressing and fatal. In instances where the triggering allergen is not known, establishing the etiology of anaphylaxis is pivotal to long-term risk management. Our recent work has identified a novel IgE antibody (Ab) response to a mammalian oligosaccharide epitope, galactose-alpha-1,3-galactose ...
Holinstat Michael M Department of Medicine, Cardeza Foundation for Hematologic Research, Thomas Jefferson University, Philadelphia, PA, - - 2013
Bivalirudin is a direct thrombin inhibitor that is increasingly used in percutaneous coronary intervention (PCI) and has been previously shown to lack inherent platelet activation. Thrombin works through activation of protease activated receptor-1 (PAR1) and PAR4 on human platelets to initiate signaling cascades leading to platelet aggregation. Despite the increasing ...
Zhu Lixin - - 2013
Nonalcoholic steatohepatitis (NASH) is a serious liver disease associated with obesity. Characterized by metabolic syndrome, hepatic steatosis, and liver inflammation, NASH is believed to be under the influence of the gut microflora. Here, the composition of gut bacterial communities of NASH, obese, and healthy children was determined by 16S ribosomal ...
Walsh Christopher T CT Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, 240 Longwood Ave., Boston, MA 02115, USA. - - 2013
Riboflavin-based coenzymes, tightly bound to enzymes catalyzing substrate oxidations and reductions, enable an enormous range of chemical transformations in biosynthetic pathways. Flavoenzymes catalyze substrate oxidations involving amine and alcohol oxidations and desaturations to olefins, the latter setting up Diels-Alder cyclizations in lovastatin and solanapyrone biosyntheses. Both C(4a) and N(5) of ...
Liu Xiaochun X University of Texas Health Science Center at Houston, Houston, TX 77030, - - 2013
To measure interferon (IFN)-inducible chemokines in the plasma of patients with systemic sclerosis (SSc) and investigate whether the chemokine levels are correlated with disease severity. Plasma levels of the IFN-inducible chemokines IFNγ-inducible protein 10 (IP-10/CXCL10), IFN-inducible T cell α chemoattractant (I-TAC/CXCL11), and monocyte chemoattractant protein 1 (CCL2) were measured in ...
Haynes Kevin K University of Pennsylvania, Department of Epidemiology and Biostatistics, Philadelphia, PA 19104, USA. - - 2013
To compare the incidence of cancer following tumor necrosis factor α (TNFα) inhibitor therapy to that with commonly used alternative therapies across multiple immune-mediated diseases. The Safety Assessment of Biological Therapeutics study used data from 4 sources: national Medicaid and Medicare databases, Tennessee Medicaid, pharmacy benefits plans for Medicare beneficiaries ...
Arora Daleep K DK Beta-Cell Biochemistry Laboratory, John D. Dingell VA Medical Center, Detroit, MI 48201, - - 2013
Emerging evidence implicates novel roles for post-translational prenylation (i.e., farnesylation and geranylgeranylation) of various signaling proteins in a variety of cellular functions including hormone secretion, survival and apoptosis. In the context of cellular apoptosis, it has been shown previously that caspase-3 activation, a hallmark of mitochondrial dysregulation, promotes hydrolysis of ...
Handlogten Michael W MW Department of Chemical and Biomolecular Engineering, University of Notre Dame, Notre Dame, IN 46556, - - 2013
The present paper describes the design of a HtTA (heterotetravalent allergen) as a multi-component experimental system that enables an integrative approach to study mast cell degranulation. The HtTA design allows presentation of two distinct haptens, each with a valency of 2, thereby better reflecting the complexity of natural allergens by ...
Nie Jingxin J Department of Radiology and BRIC, University of North Carolina at Chapel Hill, School of Medicine, Chapel Hill, NC 27599, USA. - - 2013
We propose an automated multi-atlas and multi-ROI based segmentation method for both skull-stripping of mouse brain and the ROI-labeling of mouse brain structures from the three dimensional (3D) magnetic resonance images (MRI). Three main steps are involved in our method. First, a region of interest (ROI) guided warping algorithm is ...
Bielekova Bibiana B Neuroimmunological Diseases Unit (NDU), Neuroimmunology Branch (NIB), National Institute of Neurological Disorders and Stroke (NINDS), Bethesda, MD 20892, USA. - - 2013
Daclizumab is a humanized monoclonal antibody of IgG1 subtype that binds to the Tac epitope on the interleukin-2 (IL-2) receptor α-chain (CD25), thus, effectively blocking the formation of the high-affinity IL-2 receptor. Because the high-affinity IL-2 receptor signaling promotes expansion of activated T cells in vitro, daclizumab was designed as ...
Yuan Yixuan Y School of Automation, Northwestern Polytechnical University, Xi'an, - - 2013
DICCCOL (Dense Individualized and Common Connectivity-based Cortical Landmarks) is a recently published system composed of 358 cortical landmarks that possess consistent correspondences across individuals and populations. Meanwhile, each DICCCOL landmark is localized in an individual brain's unique morphological profile, and therefore the DICCCOL system offers a universal and individualized brain ...
Chaiteerakij Roongruedee R Division of Gastroenterology and Hepatology, College of Medicine, Mayo Clinic and Mayo Clinic Cancer Center, Rochester, MN 55905, - - 2013
The associations between diabetes, smoking, obesity, and intrahepatic cholangiocarcinoma (ICC) risk remain inconclusive. Metformin is purportedly associated with a reduced risk for various cancers. This case-control study evaluated risk factors for ICC and explored the effects of metformin on ICC risk in a clinic/hospital-based cohort. ICC patients observed at the ...
Sakellariou Giorgos Konstantinos GK Department of Musculoskeletal Biology, Institute of Ageing and Chronic Disease, University of Liverpool, Liverpool, United - - 2013
The sources of cytosolic superoxide in skeletal muscle have not been defined. This study examined the subcellular sites that contribute to cytosolic superoxide in mature single muscle fibers at rest and during contractile activity. Isolated fibers from mouse flexor digitorum brevis loaded with superoxide and nitric-oxide-sensitive fluorescent probes, specific pathway ...
Tymstra Nynke - - 2012
Marginal bone changes around titanium plasma-sprayed implants (n = 240) placed in the mandibular interforaminal regions of 120 edentulous patients were assessed over 5 years of follow-up, with emphasis on the influence of the locations of the microgap and rough/smooth border. Marginal bone changes were measured on standardized radiographs. Locations ...
Kim Young-Kyun - - 2012
Primary wound closure is difficult in the posterior mandible when insufficient soft tissue is available. Primary wound closure using a buccinator musculomucosal flap after implant placement and guided bone regeneration was performed in a patient with an atrophic alveolar ridge in the posterior mandible. Implants were placed at the bone ...
Gurel Galip - - 2012
This article evaluates the long-term clinical performance of porcelain laminate veneers bonded to teeth prepared with the use of an additive mock-up and aesthetic pre-evaluative temporary (APT) technique over a 12-year period. Sixty-six patients were restored with 580 porcelain laminate veneers. The technique, used for diagnosis, esthetic design, tooth preparation, ...
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