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Han Youngshin - - 2012
BACKGROUND: There have been considerable disagreements regarding the therapeutic effects of probiotics in atopic dermatitis (AD). We performed this study to examine whether the oral administration of Lactobacillus plantarum CJLP133 improves pediatric AD. METHODS: In a randomized, double-blind, placebo-controlled study, either L. plantarum CJLP133 at a dosage of 0.5 × 10(10)  colony-forming units ...
Ohta Kouichi - - 2012
PURPOSE: To compare the thickness of each retinal layer in the parafoveal and perifoveal regions of eyes after successful closure of a macular hole (MH) by pars plana vitrectomy with internal limiting membrane (ILM) peeling to the corresponding areas of the normal fellow eyes. METHODS: Twenty-two eyes of 22 patients ...
Obinata Kaoru - - 2012
We experienced two cases of unrelated Japanese children with bacille Calmette-Guérin (BCG) multiple osteomyelitis with partial interferon (IFN)-γ receptor 1 (IFNGR1) deficiency. Heterozygous small deletions with frame shift (811 del4 and 818 del4) were detected, which were consistent with the diagnosis of partial dominant IFNGR1 deficiency. Case 1: a 2-year-old ...
Wachner Doreen - - 2012
Mixtures of suitable small particles, large particles and an "oil", spontaneously form mixed layers on a water surface. In these layers the small particles adhere to the upper interface while the large particles adhere to the lower interface. Solidification of the "oil" by photopolymerization, followed by removal of the particles ...
Farag Mohamed A - - 2012
INTRODUCTION: Brassica napus L. is a crop widely grown for its oil production and other nutritional components in the seed. In addition to the seed, other organs contain a wide range of phenolic metabolites although they have not been investigated to the same extent as in seeds. OBJECTIVE: To define ...
Wang Shen - - 2012
The evaporation of a tiny amount of water on the solid surface with different wettability has been studied by molecular dynamics simulations. From nonequilibrium MD simulations, we found that, as the surface changed from hydrophobic to hydrophilic, the evaporation speed did not show a monotonically decrease as intuitively expected, but ...
Yusuff Kazeem B - - 2012
Background The use of medicines is an action that involves a change in behaviour and it is a complex construct involving reciprocal interactions between social, environmental and cognitive factors. This is particularly true when a patient uses medicines for asymptomatic chronic conditions, requiring life-long use. Objective To identify patient-perceived medication ...
Midha Mukul Kumar - - 2012
Molecular mechanism governing biological processes leading to dietary obesity and diabetes are largely unknown. Here we study the liver proteome differentially expressed in a long-term high-fat and high sucrose diet (HFHSD)-induced obesity and diabetes mouse model. Changes in mouse liver proteins were identified using iTRAQ, offline 2D LC (SCX and ...
- - 2012
To the Editor: In their description of a patient with the hantavirus pulmonary syndrome, Rhee et al. (Aug. 2 issue)(1) note that hypoxemia developed after the patient received intravenous fluids. A lack of hemodynamic improvement in response to fluids is a hallmark of the hantavirus pulmonary syndrome,(2) and fluid restriction ...
Chen Haiping M - - 2012
Nanocrescent-like structures have become important surface enhanced Raman scattering structures because instead of relying on a few nanometer gap inter-particle plasmonic coupling to achieve local field enhancement, intra-particle plasmonic coupling between the cavity modes and the tip edges are utilized to achieve high local field enhancement at the tips. Our ...
Corrêa Juliana Moço - - 2012
In the present work, the gene xynB2, encoding a β-xylosidase II of the Glycoside Hydrolase 39 (GH39) family, of Caulobacter crescentus was cloned and successfully overexpressed in Escherichia coli DH10B. The recombinant protein (CcXynB2) was purified using nickel-Sepharose affinity chromatography, with a recovery yield of 75.5 %. CcXynB2 appeared as a ...
Prabu Gajjeraman - - 2012
Nucleoside diphosphate kinase (NDPK, EC 2.7.4.6) is a housekeeping gene, which functions in the general homeostasis of cellular nucleoside triphosphate (NTP) pools. Among the various NDPK isoforms, cytosolic NDPK1 has been shown to be the main NDPK isoform in plants, accounting for more than 70 % of total NDPK activity in ...
Sachse Alexander - - 2012
Well-dispersed Pd nanoparticles have been synthesized inside the mesoporosity of a silica monolith featuring hierarchical porosity of homogeneous interconnected macropores (4 microns) and mesopores (11 nm). These monoliths have been implemented as microreactors for selective hydrogenation reactions. Conversion and selectivity can be tuned by adjusting the flow rates of hydrogen ...
Soesbe Todd C TC Advanced Imaging Research Center, University of Texas Southwestern Medical Center, Dallas, TX, - - 2013
Paramagnetic chemical exchange saturation transfer (PARACEST) complexes are exogenous contrast agents that have great potential to further extend the functional and molecular imaging capabilities of magnetic resonance. As a result of the presence of a central paramagnetic lanthanide ion (Ln(3+) ≠ La(3+) , Gd(3+) , Lu(3+) ) within the chelate, ...
Alexander Matthew P - - 2012
High-levels of transcription through a gene stimulate spontaneous mutation rate, a phenomenon termed transcription-associated mutation (TAM). While transcriptional effects on specific mutation classes have been identified using forward mutation and frameshift-reversion assays, little is yet known about transcription-associated base substitutions in yeast. To address this issue, we developed a new ...
Iriarte José Luis - - 2012
Anthropogenic (aquaculture) changes in environment nutrient concentrations may affect phytoplankton (biomass and taxa composition) in marine coastal waters off the Chilean Patagonia. The effects of adding nitrate (NO(3) (-)) to natural phytoplankton assemblages were evaluated considering biomass, cell abundance, and taxonomic composition. Microcosm experiments were performed in the spring, summer, ...
Herrero-Medrano J M - - 2012
The Chato Murciano (CM), a pig breed from the Murcia region in the southeastern region of Spain, is a good model for endangered livestock populations. The remaining populations are bred on approximately 15 small farms, and no herdbook exists. To assess the genetic threats to the integrity and survival of ...
Zou Haidong - - 2012
PURPOSE: To assess the time trade-off (TTO) utility values in patients with persistent visually disabling vitreous floaters (DVF) and to determine the reliability and validity of TTO methods in DVF patients. METHODS: Prospective cross-sectional questionnaire survey: Eligible patients with persistent DVF referred to the Shanghai First People's Hospital outpatient service ...
Chervin A S - - 2012
Adoptive T-cell therapies have shown significant promise in the treatment of cancer and viral diseases. One approach, which introduces antigen-specific T-cell receptors (TCRs) into ex vivo activated T cells, is designed to overcome central tolerance mechanisms that prevent responses by endogenous T-cell repertoires. Studies have suggested that use of higher-affinity ...
Zivković Daniel - - 2012
Continuous progress in empirical population genetics based on the whole-genome polymorphism data requires the theoretical analysis of refined models in order to interpret the evolutionary history of populations with adequate accuracy. Recent studies focus prevalently on the aspects of demography and adaptation, whereas age structure (for example, in plants via ...
Cai Qian - - 2012
PURPOSE: To evaluate the effectiveness of an endoscopy-assisted surgical technique, designed to leave a scar-free neck, for removing large benign thyroid tumors. METHODS: The subjects were 63 patients who underwent endoscopy-assisted surgery via a subclavian approach (endoscopic group) and 79 patients who underwent similar surgery via the conventional approach (conventional ...
Zhao Guanjia - - 2012
In this paper, we present a rapid, high-yield, low-end and low-cost fabrication of nanojet motors using a template directed electrochemical deposition method. Using an electrochemical deposition method, the bubble-ejecting nanojets were grown within the alumina template, which is commercially available. These fabricated nanosized devices have typical dimensions of 300 nm ...
Soong Lynn L Department of Microbiology and Immunology, University of Texas Medical Branch, Galveston, TX 77555-1070, USA. - - 2012
The outcomes of Leishmania infection are determined by host immune and nutrition status, parasite species, and co-infection with other pathogens. While subclinical infection and self-healing cutaneous leishmaniasis (CL) are common, uncontrolled parasite replication can lead to non-healing local lesions or visceral leishmaniasis (VL). It is known that infection control requires ...
Ptinopoulou Anastasia G - - 2012
Data from randomized clinical trials and epidemiological evidence identify systemic hypertension as the second most common modifiable risk factor for chronic kidney disease (CKD) progression after diabetes mellitus. CKD may progress silently over the years and early diagnosis and control of hypertension is of major importance in delaying renal function ...
Liu Jun - - 2012
The efficient and concise synthesis of (-)-orthodiffenes A and C has been accomplished for the first time in 8 steps from readily available chiral synthons, D-mannose and D-ethyl lactate. Our work confirmed the complete structure of orthodiffenes A and C, including their absolute stereochemistry. The key steps of our total ...
Wales Jackie - - 2012
A 10-year retrospective case note study of adults with eating disorders at low weight examined levels of service consumption and the outcome in terms of body mass index. Records of 202 such patients, referred to a specialist secondary service, were studied. Just over one quarter of the patients failed to ...
Doyle John J - - 2012
This piece is being submitted as a short commentary for the special edition on Oceans and Human Health (OHH). It is written from the perspective of a student who has attended all three biennial Gordon Research Conferences and Seminars on OHH beginning in 2008.
Wick P A - - 2012
BACKGROUND AND OBJECTIVE: Anti-apolipoprotein A-1 (anti-apoA-1) IgG is a potential marker of atherosclerotic plaque vulnerability and cardiovascular complications. In patients with periodontitis the presence of anti-apoA-1 IgGs in serum and their association with atherosclerosis is unknown. MATERIAL AND METHODS: One-hundred and thirty subjects with periodontal disease and 46 healthy subjects, ...
Hashimoto Daisuke - - 2012
In patients undergoing pancreaticoduodenectomy, leakage from the pancreatic anastomosis remains an important cause of morbidity and contributes to prolonged hospitalization and mortality. Recently, a new end-to-end pancreaticojejunostomy technique without the use of any stitches through the pancreatic texture or pancreatic duct has been developed. In this novel anastomosis technique, the ...
Walker Christine - - 2012
BACKGROUND: Following a workshop with people with multiple conditions, the Chronic Illness Alliance undertook a literature review to explore current literature about multiple conditions. METHODS: The literature search was performed using Medline, CINAHL, Google Scholar and Cochrane Library employing an extensive list of search terms and limited to English language ...
Do T H T - - 2012
An occurrence and a magnitude of alcoholic liver diseases depend on the balance between ethanol-induced injury and liver regeneration. Like ethanol, polyamines including putrescine, spermidine, and spermine modulate cell proliferation. Thus, the purpose of this study was to evaluate the relationship between effect of ethanol on hepatocyte (HC) proliferation and ...
Schmidt J - - 2012
Detection of acute cardiac dysfunction and differential diagnosis of low cardiac output syndrome is challenging for emergency physicians. For the critical ill patient it is essential to rapidly identify the underlying disease to initiate the correct therapy and optimize patient outcome. Echocardiography is the diagnostic tool of choice for the ...
Paiva Carlos Eduardo - - 2012
PURPOSES: The purposes of this study are to evaluate the impact of cancer-related fatigue (CRF) on quality of life (QoL), and to identify its clinical predictors. In addition, the authors investigated the prognostic impact of CRF and its relationship with the inflammatory marker C-reactive protein. METHOD: Data regarding patient characteristics, ...
Hagag U - - 2012
The purpose of this study was to provide a detailed computed tomographic (CT) anatomic reference for the dromedary camel tarsus. Six cadaver pelvic limbs, obtained from three clinically and radiographically sound dromedary camels, were scanned in both soft tissue and bone windows starting from the calcaneal tuber towards the proximal ...
Bonifácio Clarissa Calil - - 2012
OBJECTIVE: Good survival rates (SR) have been reported for occlusal-atraumatic restorative treatment (ART) restorations but not for approximal-ART restorations. The high-viscosity consistency of the glass ionomer cement (GIC) may lead to its incorrect adaptation into the cavity and thus to failure of the restoration. Because the use of a flowable ...
Oshima Hiroko - - 2012
Accumulating evidence indicates that inflammation plays a critical role in cancer development. Cyclooxygenase-2 (COX-2) is a rate-limiting enzyme for prostanoid biosynthesis, including prostaglandin E(2) (PGE(2)), and plays a key role in both inflammation and cancer. It has been demonstrated that inhibition of COX-2 and PGE(2) receptor signaling results in the ...
Liu Dazhong - - 2012
Genetic polymorphisms of p53 codon 72 are thought to have significant effects on the metabolism of environmental carcinogens and thus on lung cancer risk, but the reported results are not always consistent. The aim of this study is to investigate the relationship between p53 codon 72 genetic polymorphisms and tobacco ...
Penin Lucie - - 2012
Mass bleaching events resulting in coral mortality are among the greatest threats to coral reefs, and are projected to increase in frequency and intensity with global warming. Achieving a better understanding of the consistency of the response of coral assemblages to thermal stress, both spatially and temporally, is essential to ...
Dai Boyi - - 2012
Abstract Discus throwing performance is associated with technique variables. However, the relationships between technique variability and performance in discus throwing are unknown. Video clips of three throws each by 18 male and 15 female discus throwers were collected during a competition. Two-dimensional coordinate data were manually digitised and transferred into ...
Lichter Seth - - 2012
A wide range of molecules, from inorganic to biological, self-assemble on surfaces. Previous studies have elucidated many features of solute reorganization on surfaces using coarse-grained modeling, implicit solvent, and constraints such as chemically bonding the solute to the surface. Using molecular dynamics simulations under various combinations of interaction parameters, solute ...
Chen Yan - - 2012
The purpose of this study was to develop an ophthalmic drug delivery system for cyclosporine A (CsA) based on glyceryl monooleate (GMO)/poloxamer 407 liquid crystalline nanoparticles with reduced ocular irritancy and improved corneal penetration. CsA-loaded liquid crystalline nanoparticles were prepared via fragmentation of a bulk GMO/poloxamer 407 cubic phase gel ...
Stoler Justin - - 2012
The advent and rapid spread of sachet drinking water in West Africa presents a new challenge for providing sustainable access to global safe water. Sachet water has expanded drinking water access and is often of sufficient quality to serve as an improved water source for Millennium Development Goals (MDG) monitoring ...
Choi Yeongchull - - 2012
Objectives  To investigate the magnitude and characteristics of the economic burden resulting from acute pesticide poisoning (APP) in South Korea. Methods  The total costs of APP from a societal perspective were estimated by summing the direct medical and non-medical costs together with the indirect costs. Direct medical costs for patients ...
Pandey Mithilesh K - - 2012
Pilonidal sinus is usually present in sacrococcygeal region. The common presentations are the cellulitis, abscess or sinus. Rarely malignant change may be seen in chronic pilonidal sinus. We report a case of chronic pilonidal sinus complicated with squamous cell carcinoma.
Carneiro F - - 2012
In 1998, Guilford et al. identified the hereditary diffuse gastric cancer (HDGC) syndrome, caused by germline alterations at the CDH1 (E-cadherin) gene. To date, 141 probands harboring more than 100 different germline CDH1 alterations, mainly point mutations and large deletions, have been described. In mutation-positive individuals prophylactic total gastrectomy is recommended. The ...
Carlsson Göran - - 2012
AIM: Severe congenital neutropenia (SCN) is a rare disorder of myelopoiesis characterized by neutropenia, recurrent bacterial infections, and a maturation arrest of the myelopoiesis in the bone marrow. Homozygous mutations in the HAX1 gene were described in patients with autosomal recessive SCN or Kostmann disease. Some of these patients display ...
Kaasalainen Sharon - - 2012
BACKGROUND: Providing palliative care in long-term care (LTC) homes is an area of growing importance. As a result, attention is being given to exploring effective palliative care learning strategies for personal support workers (PSWs) who provide the most hands-on care to LTC residents. AIM: The purpose of this intervention was ...
de Andrade Freitas Oliveira Luciana Soares - - 2012
BACKGROUND: Ankylosing spondylitis (AS) is a chronic inflammatory disease with multiple articular and para-articular involvement that has a predilection for the axial skeleton. In spite of its high prevalence, ankylosis secondary to AS is a rare condition. CASE REPORT: A 31-year-old male diagnosed with AS was referred for computed tomography ...
Jochimsen Marc C - - 2012
The link between compensatory dynamics and regime shifts is not well understood. We analyse a regime shift in phytoplankton in a large lake with respect to: (1) environmental forcing and (2) the type of dynamics (compensatory or synchronous) between phytoplankton groups. The regime shift in phytoplankton was related to gradual ...
Landrot Gautier - - 2012
Layered, poorly-crystalline Mn(IV)O2 phases are abundant in the environment. These mineral phases may rapidly oxidize Cr(III) to more mobile and toxic Cr(VI) in soils. There is still, however, little knowledge of how Cr(III) oxidation by Mn(IV)O2 proceeds at the microscopic and molecular levels. Therefore, the sorption mechanisms of Cr(III) and ...
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