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Liu Wenqi - - 2012
This paper describes a novel double phase transforming organogel (gel-sol-gel') composed of nontoxic beta-cyclodextrin, potassium carbonate and 1, 2-propylene glycol. The gel-sol-gel' transforming processes are followed by a reversible gel-sol transforming process and an irreversible sol-gel' transforming process based on heating. The gel-sol-gel' transformation is accompanied by microstructure changes from ...
Doll Joy - - 2012
The Core Competencies for Collaborative Practice identify the skills needed by every health care provider to be successful in implementing interprofessional practice. Health professions students need to build skills for interprofessional practice as emerging professionals. Reflection is a core skill needed for successful interprofessional practices. This study identifies themes from ...
Aiboushev Arseniy - - 2012
Transient absorption spectra of gold nanoparticles (AuNPs) embedded in mesoporous TiO(2) film were studied by a femtosecond laser photolysis pump-probe technique using 25 fs pulses at 740 nm (1.68 eV) and a low fluence of 24 μJ cm(-2). The shift of the bleaching peak in transient spectra by ∼100 meV ...
Gagnaire Beatrice - - 2012
In this study, we investigated the effects of depleted uranium (DU), the by-product of nuclear enrichment of uranium, on several parameters related to oxidative stress, detoxification, and the defence system in the zebrafish Danio rerio. Several parameters were recorded: phenoloxidase-like (PO) activity, reactive oxygen species (ROS) production, and 7-ethoxyresrufin-O-deethylase (EROD) ...
Ortega N - - 2012
We report the breakdown electric field and energy density of laser ablated BaTiO(3)/Ba((1-x))Sr(x)TiO(3) (x = 0.7) (BT/BST) relaxor-ferroelectric superlattices (SLs) grown on (100) MgO single crystal substrates. The dielectric constant shows a frequency dispersion below the dielectric maximum temperature (T(m)) with a merger above T(m) behaving similarly to relaxors. It also follows ...
Yan Xiang X Department of Psychology, Key Laboratory of Machine Perception, Ministry of Education, Beijing Engineering Research Center of Intelligent Rehabilitation Engineering, Peking University, Beijing, - - 2013
Studies of motor generalization usually perturb hand reaches by distorting visual feedback with virtual reality or by applying forces with a robotic manipulandum. Whereas such perturbations are useful for studying how the central nervous system adapts and generalizes to novel dynamics, they are rarely encountered in daily life. The most ...
Wang Dong-Mei DM Department of Hematology, The First Affiliated Hospital of Nanjing Medical University, Jiangsu Province Hospital, Nanjing, PR - - 2012
Human oncogene DEK has been shown to be upregulated in a number of neoplasms. The purpose of this study was to investigate DEK expression level in chronic lymphocytic leukemia (CLL), analyze the correlation between DEK expression and CLL prognostic markers, and characterize the role of DEK in the response to ...
Furley Philip - - 2012
In two experiments, we transferred perceptual load theory to the dynamic field of team sports and tested the predictions derived from the theory using a novel task and stimuli. We tested a group of college students (N = 33) and a group of expert team sport players (N = 32) on a general perceptual ...
Legg David A DA Department of Earth Sciences and Engineering, Imperial College London, London SW7 2BP, UK. - - 2012
Extant arthropods are diverse and ubiquitous, forming a major constituent of most modern ecosystems. Evidence from early Palaeozoic Konservat Lagerstätten indicates that this has been the case since the Cambrian. Despite this, the details of arthropod origins remain obscure, although most hypotheses regard the first arthropods as benthic predators or ...
Gryff-Keller Adam - - 2012
Magnetic shielding and indirect spin-spin coupling phenomena are tensorial properties and both their isotropic and anisotropic parts do affect NMR spectra. The involved interaction tensors, σ^ and J^, can nowadays be theoretically calculated, although the reliability of such methods in the case of anisotropic parameters, Δσ and ΔJ, in systems ...
Ordoñana Juan R - - 2012
PURPOSE: To describe the major findings in the literature regarding associations between biological and genetic factors and social functioning, paying special attention to: (1) heritability studies on social functioning and related concepts; (2) hypothesized biological pathways and genetic variants that could be involved in social functioning, and (3) the implications ...
Xu Chanzhi - - 2012
Purpose: To develop and validate a quality of life (QOL) instrument for patients with colorectal cancer, QLICP-CR. Methods: Using the programmed decision method and the theory in instrument development, the QLICP-CR was developed and evaluated based on the data measuring QOL thrice from a sample of 110 inpatients of colorectal ...
Cho Jun-Hyeong - - 2012
Pituitary adenylate cyclase-activating polypeptide (PACAP) is a pleiotropic neuropeptide expressed in the brain, where it may act as a neuromodulator or neurotransmitter contributing to different behavioral processes and stress responses. PACAP is highly expressed in the amygdala, a subcortical brain area involved in both innate and learned fear, suggesting a ...
Zhao Yadong - - 2012
This study investigates the resonant effects in nonlinear photon absorption in femtosecond laser ablation of Nd-doped silicate glass (Nd:glass). During the femtosecond laser ablation process, the resonant ablation threshold fluence is decreased by up to 40% compared with that of ordinary ablation. However, it is found that the resonant effect ...
Hsu Wei-Bin - - 2013
Transcription and replication of the influenza A virus RNA genome occur in the nucleus through the viral RNA-dependent RNA polymerase consisting of PB1, PB2, and PA. Cellular factors that associate with the viral polymerase complex play important roles in these processes. To look for cellular factors that could associate with ...
Firth Cadhla - - 2012
Hantaviruses are important contributors to disease burden in the New World, yet many aspects of their distribution and dynamics remain uncharacterized. To examine the patterns and processes that influence the diversity and geographic distribution of hantaviruses in South America, we performed genetic and phylogeographic analyses of all available South American ...
Ohto Umeharu U Graduate School of Pharmaceutical Sciences, The University of Tokyo, Hongo, Tokyo 113-0033, - - 2012
TLR4 polymorphism replacing Asp-299 with Gly and Thr-399 with Ile (D299G/T399I) causes LPS hyporesponsiveness. TLR4(SNPs)·MD-2·LPS exhibits an agonistic 2:2:2 architecture. Local structural differences were observed around D299G, but not around T399I, SNP site. These local differences cause the modulation of surface properties of TLR4, which may affect ligand binding. This ...
Kudsi Omar Yusef - - 2012
BACKGROUND: It has been hypothesized that alcohol metabolism is altered after weight-loss surgery (WLS), with a few studies suggesting a high prevalence of postoperative problem drinking. However, many of these studies were methodologically limited by lack of preoperative alcohol use data, high loss to follow-up, and/or nonsystematic ascertainment of alcohol ...
Andersen E S - - 2012
Variations in bladder position, shape and volume cause uncertainties in the doses delivered to this organ during a course of radiotherapy for pelvic tumors. The purpose of this study was to evaluate the potential of dose accumulation based on repeat imaging and deformable image registration (DIR) to improve the accuracy ...
Schraiber Joshua G JG Department of Integrative Biology, University of California, Berkeley, CA 94720-3140, - - 2012
We examine the distribution of heterozygous sites in nine European and nine Yoruban individuals whose genomic sequences were made publicly available by Complete Genomics. We show that it is possible to obtain detailed information about inbreeding when a relatively small set of whole-genome sequences is available. Rather than focus on ...
Pina M Fatima - - 2012
Paroxetine hydrochloride (HCl) is an anti-depressant drug, reported to exist in the anhydrous form (Form II) and as a stable hemihydrate (Form I). In this study, we investigate the hydration behaviour of paroxetine HCl Form II with a view to understanding both the nature of the interaction with water and ...
Han Rongfei - - 2012
The epithelial-mesenchymal transition (EMT) is a fundamental process governing morphogenesis in multicellular organisms and has recently been implicated in promoting carcinoma invasion and metastasis. Besides their therapeutic effects, accumulating evidences suggest that chemotherapeutic agents also induced EMT and enhanced the malignancy of treated cancer cells; however, the mechanism(s) still remains ...
Tiribelli Mario - - 2013
To assess the impact of BCR-ABL kinase domain mutations on dasatinib response in elderly chronic myeloid leukemia (CML) patients, we analyzed the outcome of 76 individuals aged >60 affected by imatinib-resistant chronic-phase CML. We found that 36 cases (47 %) displayed mutations before dasatinib. Compared to non-mutated patients, subjects with point ...
McDonald S D - - 2012
AIMS: Compared with women with uncomplicated pregnancies, women with a history of pre-eclampsia have two to five times the risk of cardiovascular disease. It is not known whether this risk is related to albuminuria, a known cardiovascular risk factor that is part of the definition of pre-eclampsia and that often ...
Pedrero Zoyne - - 2012
Microbial activity is recognised to play an important role on Hg methylation in aquatic ecosystems. However, the mechanism at the cellular level is still poorly understood. In this work subcellular partitioning and transformation of Hg species in two strains: Desulfovibrio sp. BerOc1 and Desulfovibrio desulfuricans G200 (which exhibit different Hg ...
Loko Marc-Arthur - - 2012
BACKGROUND: The aim of this study was to describe changes in repeated liver stiffness (LS) measurements and to assess the determinants of increase in LS in HIV-HCV-coinfected patients. METHODS: HIV-HCV-coinfected adults enrolled in the ANRS CO 13 HEPAVIH cohort, for whom two results of LS, evaluated over ≥24 months, were ...
Williams Leslie K - - 2012
The increasing prevalence of diabetes has accelerated the search for new drugs derived from natural sources. To define the functional features of two such families of compounds, the flavonols and the ethyl caffeates, we have determined the high-resolution structures of representative inhibitors in complex with human pancreatic α-amylase. Myricetin binds ...
Breton Daniel James - - 2012
We describe a microcontroller-based ice core melting and data logging system allowing simultaneous depth co-registration of a continuous flow analysis (CFA) system (for microparticle and conductivity measurement) and a discrete sample analysis system (for geochemistry and microparticles), both supplied from the same melted ice core section. This hybrid melting system ...
Péterfi Zoltán Z Institute of Experimental Medicine, Hungarian Academy of Sciences, H-1083 Budapest, - - 2012
Although endocannabinoids have emerged as essential retrograde messengers in several forms of synaptic plasticity, it remains controversial whether they mediate long-term depression (LTD) of glutamatergic synapses onto excitatory and inhibitory neurons in the hippocampus. Here, we show that parvalbumin- and somatostatin/metabotropic glutamate receptor 1(a) (mGlu(1a))-positive GABAergic interneurons express diacylglycerol lipase-α ...
Zhang Hanwei - - 2012
We report an all-fiberized, high-pulse-energy, high-average-power, Q-switched fiber master oscillator power amplifier (MOPA) oscillated at 1064 nm. The seed source is an acousto-optic Q-switched fiber laser, which is driven by an arbitrary waveform generator. A preamplifier is developed to boost the average power to about 3 W. Finally, we achieved an average ...
Chen Bing - - 2012
The self-imaging phenomena in multimode Bragg reflection waveguides (BRWs) have been predicted and investigated by using the plane-wave expansion method and the finite-difference time-domain method. A compact wavelength splitter based on self-imaging principles in BRWs is presented, and its transmission characteristics are investigated by using the finite-difference time-domain method. Calculated ...
Nechuta Sarah - - 2012
Data from in vitro and animal studies support a protective role for tea in the etiology of digestive system cancers; however, results from prospective cohort studies have been inconsistent. In addition, to our knowledge, no study has investigated the association of tea consumption with the incidence of all digestive system ...
Beery Annaliese K AK Robert Wood Johnson Health & Society Scholar at University of California at San Francisco, San Francisco, CA 04143, USA. - - 2012
The enzyme telomerase lengthens telomeres-protective structures containing repetitive DNA sequences at chromosome ends. Telomere shortening is associated with diseases of ageing in mammals. Chronic stress has been related to shorter immune-cell telomeres, but telomerase activity under stress may be low, permitting telomere loss, or high, partially attenuating it. We developed ...
Dyck Miriam - - 2012
While impairments in emotion recognition are consistently reported in schizophrenia, there is some debate on the experience of emotion. Only few studies investigated neural correlates of emotional experience in schizophrenia. The present functional magnetic resonance imaging (fMRI) study compared a standard visual mood induction paradigm with an audiovisual method aimed ...
Dogra Shivani - - 2012
The authors report an 18-mo-old girl who presented with features of incomplete Kawasaki disease and was refractory to intravenous immunoglobulin and infliximab treatment. She subsequently responded to pulse intravenous methylprednisolone therapy. The diagnostic dilemma arose after 2 mo when she developed clinical features suggestive of systemic onset juvenile idiopathic arthritis. Since ...
Barrot Michel M Institut des Neurosciences Cellulaires et Intégratives, Centre National de la Recherche Scientifique, Université de Strasbourg, 67084 Strasbourg, France. - - 2012
A new mesopontine structure exerting a strong influence on dopamine systems has recently been defined: the tail of the ventral tegmental area/rostromedial tegmental nucleus (tVTA/RMTg). This review presents a neuroanatomical, physiological, and behavioral overview of some of the recent and ongoing research on this brain region and its relationship with ...
Caballero Fernando - - 2012
K(+) acquisition by Arabidopsis roots is mainly mediated by the high-affinity K(+) transporter AtHAK5 and the inward-rectifier K(+) channel AtAKT1. This model is probably universal to plants. Mutant plants lacking these two systems (athak5,atakt1) take up K(+) and grow when the external K(+) concentration is above a certain level, indicating ...
Liu Yonghua - - 2012
SCY1-like 1-binding protein 1 (SCYL1BP1) is a newly identified transcriptional activator domain containing a protein with many unknown biological functions. Recently emerging evidence has revealed that it is a novel regulator of the p53 pathway, which is required for neurite outgrowth and regeneration. Here we present evidence that SCYL1BP1 inhibits ...
Nakagawa Saori - - 2012
Micafungin is an echinocandin antifungal agent that is important for treating candidiasis in emergency and intensive care medicine; however, current methods for measuring micafungin plasma levels are lengthy and complicated. We report a simple quantitative method using column-switching high-performance liquid chromatography (HPLC) for determining micafungin in human plasma samples. Human ...
Karriker-Jaffe Katherine J KJ Department of Health Behavior, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA. - - 2013
Adolescents develop within multiple contexts that synergistically influence their behavior and health. To understand the simultaneous influence of neighborhood and family contexts on adolescents, this study examined relationships of neighborhood socioeconomic disadvantage, neighborhood social disorganization, family conflict, parent-child bonding and parental control with trajectories of physical and social aggression. The ...
Eckenhoff William T - - 2012
Kinetic and mechanistic studies of atom transfer radical addition (ATRA) catalyzed by copper complexes with tris(2-pyridylmethyl)amine (TPMA) ligand were reported. In solution, the halide anions were found to strongly coordinate to [Cu(I)(TPMA)](+) cations, as confirmed by kinetic, cyclic voltammetry, and conductivity measurements. The equilibrium constant for atom transfer (K(ATRA) = ...
Rishal Ida - - 2012
Automated analyses of neuronal morphology are important for quantifying connectivity and circuitry in vivo, as well as in high content imaging of primary neuron cultures. The currently available tools for quantification of neuronal morphology are either highly expensive commercial packages or cannot provide automated image quantifications at single cell resolution. ...
Frydenberg Karin - - 2012
General practitioners have a key role in updating their patients' medication. Poor communication regarding patients' drug use may easily occur when patients cross health care levels. We wanted to explore whether such inadequate communication leads to errors in patients' medication on admission, during hospital stay, and after discharge, and whether ...
Wu Zhong - - 2012
Immune thrombocytopenia (ITP) is an autoimmune disorder described as autoantibody-mediated platelet deterioration. Platelets with affiliated IgG are targeted for exploitation by Fc receptor-mediated phagocytic cellular material within the reticuloendothelial system. The objective of this research is to investigate the relationship between the appearance of FC gamma receptors (FCGR) IIB and ...
Parvez Khaled - - 2012
The high cost of platinum based electrocatalysts for the oxygen reduction reaction (ORR) has hindered the practical application of fuel cells. Thanks to its unique chemical and structural properties, nitrogen doped graphene (NG) is among the most promising metal-free catalysts for replacing platinum. In this work, we have developed a ...
Kitson Alex P - - 2012
Docosahexaenoic acid (DHA, 22:6n-3) is higher in the blood and tissues of females relative to males, but the underlying mechanism is not clear. The present study examined the expression of enzymes involved in the biosynthesis of DHA from short-chain n-3 polyunsaturated fatty acids in male and female rats (n = ...
Chung J-W - - 2012
Klinefelter's syndrome, which is characterized by small testes, gynecomastia, hypogonadism, and infertility, is the most common cause of primary testicular failure, and commonly has an XXY karyotype. Deep vein thrombosis and thomboembolic events are a rare occurrence in these patients. Although the exact mechanism is not completely understood, it is ...
Grant Clare F J - - 2012
ABSTRACT: Understanding the mechanisms that maintain protective antibody levels after immunisation is important for vaccine design. In this study, we have determined the kinetics of plasma and memory B cells detectable in the blood of cattle immunised with model T-dependent or T-independent antigens. Immunisation with the T-D antigen resulted in ...
Castrén Eero - - 2012
Brain development in neurodevelopmental disorders has been considered to comprise a sequence of critical periods, and abnormalities occurring during early development have been considered irreversible in adulthood. However, findings in mouse models of neurodevelopmental disorders, including fragile X, Rett syndrome, Down syndrome, and neurofibromatosis type I suggest that it is ...
Pal Atasi - - 2012
A stable and tunable thulium-doped "all-fiber" laser offering a narrow linewidth has been created specifically to act as a compact and simple laser source for gaseous CO<sub>2</sub> detection. This has been done through a careful design to match the laser output wavelengths to the CO<sub>2</sub> absorption lines at 1.875 and ...
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