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Flege Christian - - 2012
In-stent restenosis is still an important issue and stent thrombosis is an unresolved risk after coronary intervention. Biodegradable stents would provide initial scaffolding of the stenosed segment and disappear subsequently. The additive manufacturing technology Selective Laser Melting (SLM) enables rapid, parallel, and raw material saving generation of complex 3- dimensional ...
Caraballo Deborah - - 2012
Recent literature describes methods to reduce "preventable" hospital-acquired venous thromboembolism; however, there is a paucity of data on "preventable" bleeding. While risk assessment models exist for both thrombosis and bleeding, these concepts should be differentiated from whether the event was preventable or non-preventable. Here we describe a protocol to identify, ...
Teramura T - - 2012
Background.  High-performance sunscreen protects both healthy consumers and photosensitive patients from strong ultraviolet (UV) exposure. The sun-protection factor (SPF), which indicates the efficacy of UV protection, is determined using a prescribed sunscreen application thickness of 2.0 mg/cm(2) . Therefore, users should apply at least 2.0 mg/cm(2) of sunscreen to obtain the level ...
Zhang Hanwei - - 2012
We report an all-fiberized, high-pulse-energy, high-average-power, Q-switched fiber master oscillator power amplifier (MOPA) oscillated at 1064 nm. The seed source is an acousto-optic Q-switched fiber laser, which is driven by an arbitrary waveform generator. A preamplifier is developed to boost the average power to about 3 W. Finally, we achieved an average ...
Chen Bing - - 2012
The self-imaging phenomena in multimode Bragg reflection waveguides (BRWs) have been predicted and investigated by using the plane-wave expansion method and the finite-difference time-domain method. A compact wavelength splitter based on self-imaging principles in BRWs is presented, and its transmission characteristics are investigated by using the finite-difference time-domain method. Calculated ...
Dyck Miriam - - 2012
While impairments in emotion recognition are consistently reported in schizophrenia, there is some debate on the experience of emotion. Only few studies investigated neural correlates of emotional experience in schizophrenia. The present functional magnetic resonance imaging (fMRI) study compared a standard visual mood induction paradigm with an audiovisual method aimed ...
Dogra Shivani - - 2012
The authors report an 18-mo-old girl who presented with features of incomplete Kawasaki disease and was refractory to intravenous immunoglobulin and infliximab treatment. She subsequently responded to pulse intravenous methylprednisolone therapy. The diagnostic dilemma arose after 2 mo when she developed clinical features suggestive of systemic onset juvenile idiopathic arthritis. Since ...
Caballero Fernando - - 2012
K(+) acquisition by Arabidopsis roots is mainly mediated by the high-affinity K(+) transporter AtHAK5 and the inward-rectifier K(+) channel AtAKT1. This model is probably universal to plants. Mutant plants lacking these two systems (athak5,atakt1) take up K(+) and grow when the external K(+) concentration is above a certain level, indicating ...
Nakagawa Saori - - 2012
Micafungin is an echinocandin antifungal agent that is important for treating candidiasis in emergency and intensive care medicine; however, current methods for measuring micafungin plasma levels are lengthy and complicated. We report a simple quantitative method using column-switching high-performance liquid chromatography (HPLC) for determining micafungin in human plasma samples. Human ...
Karriker-Jaffe Katherine J - - 2012
Adolescents develop within multiple contexts that synergistically influence their behavior and health. To understand the simultaneous influence of neighborhood and family contexts on adolescents, this study examined relationships of neighborhood socioeconomic disadvantage, neighborhood social disorganization, family conflict, parent-child bonding and parental control with trajectories of physical and social aggression. The ...
Eckenhoff William T - - 2012
Kinetic and mechanistic studies of atom transfer radical addition (ATRA) catalyzed by copper complexes with tris(2-pyridylmethyl)amine (TPMA) ligand were reported. In solution, the halide anions were found to strongly coordinate to [Cu(I)(TPMA)](+) cations, as confirmed by kinetic, cyclic voltammetry, and conductivity measurements. The equilibrium constant for atom transfer (K(ATRA) = ...
Rishal Ida - - 2012
Automated analyses of neuronal morphology are important for quantifying connectivity and circuitry in vivo, as well as in high content imaging of primary neuron cultures. The currently available tools for quantification of neuronal morphology are either highly expensive commercial packages or cannot provide automated image quantifications at single cell resolution. ...
Wu Zhong - - 2012
Immune thrombocytopenia (ITP) is an autoimmune disorder described as autoantibody-mediated platelet deterioration. Platelets with affiliated IgG are targeted for exploitation by Fc receptor-mediated phagocytic cellular material within the reticuloendothelial system. The objective of this research is to investigate the relationship between the appearance of FC gamma receptors (FCGR) IIB and ...
Parvez Khaled - - 2012
The high cost of platinum based electrocatalysts for the oxygen reduction reaction (ORR) has hindered the practical application of fuel cells. Thanks to its unique chemical and structural properties, nitrogen doped graphene (NG) is among the most promising metal-free catalysts for replacing platinum. In this work, we have developed a ...
Kitson Alex P - - 2012
Docosahexaenoic acid (DHA, 22:6n-3) is higher in the blood and tissues of females relative to males, but the underlying mechanism is not clear. The present study examined the expression of enzymes involved in the biosynthesis of DHA from short-chain n-3 polyunsaturated fatty acids in male and female rats (n = ...
Chung J-W - - 2012
Klinefelter's syndrome, which is characterized by small testes, gynecomastia, hypogonadism, and infertility, is the most common cause of primary testicular failure, and commonly has an XXY karyotype. Deep vein thrombosis and thomboembolic events are a rare occurrence in these patients. Although the exact mechanism is not completely understood, it is ...
Grant Clare F J - - 2012
ABSTRACT: Understanding the mechanisms that maintain protective antibody levels after immunisation is important for vaccine design. In this study, we have determined the kinetics of plasma and memory B cells detectable in the blood of cattle immunised with model T-dependent or T-independent antigens. Immunisation with the T-D antigen resulted in ...
Frakt Austin B - - 2012
By virtue of the Supreme Court's decision on the constitutionality of the Patient Protection and Affordable Care Act, states may reject the law's expansion of Medicaid without losing all Medicaid funding from the federal government. The Court's ruling potentially permits a range of Medicaid options for states, including some that ...
Nguyen Le Hoa - - 2012
In this paper, we address the control problem of bifurcations in the Morris-Lecar (ML) neuron model. With the use of a dynamic state-feedback control, two Hopf bifurcation points in the ML neuron model with Type II excitability can be relocated to new desired locations simultaneously. Also, with the proposed control ...
Oswal Dhawal P - - 2012
Sarin is a toxic organophosphorus (OP) nerve agent that has been reported to cause long-term alterations in behavioral and neuropsychological processes. The present study was designed to investigate the effect of low dose sarin exposure on the monoamine neurotransmitter systems in various brain regions of mice. The rationale was to ...
Yan Biao - - 2012
The shortage of freshwater resource in many countries leads to a shift to develop aquaculture in brackish water and sea water. Tilapias are euryhaline that can thrive from freshwater to full sea water. They and their hybrids are the best candidate species for cultivation in brackish habitats. Thus, understanding their ...
Braun M G - - 2012
We report on a retrospective study of 16 rheumatoid arthritis (RA) patients with reduction in size of pulmonary and peripheral rheumatoid nodules following treatment with rituximab (RTX). The 8 female and 8 male patients had an average disease duration of 12.2 years, 88 % were anti-CCP positive and 94 % seropositive. Prior ...
Metz-Flamant C - - 2012
Leukemia is one of the earliest cancer effects observed after acute exposure to relatively high doses of ionizing radiation. Leukemia mortality after external exposure at low doses and low-dose rates has been investigated at the French Atomic Energy Commission (CEA) and Nuclear Fuel Company (AREVA NC) after an additional follow-up ...
Nazir Shahid - - 2012
Chlorophyll biosynthesis is catalyzed by two multi subunit enzymes; a light-dependent and a light-independent protochlorophyllide oxidoreductase. The light-independent enzyme consists of three subunits (ChlL, ChlN and ChlB) in photosynthetic bacteria and plastids in which the chlB gene encodes the major subunit that catalyzes the reduction of protochlorophyllide to chlorophyllide. We ...
Zhang Yan - - 2012
Transcription factors regulate gene expression by binding to specific DNA sequences within the regulatory regions of genes, and have become potential targets in clinical diagnosis and drug development. However, traditional approaches for the detection of transcription factors are usually laborious and time-consuming with a low sensitivity. Here, we develop an ...
Zhao Yadong - - 2012
This study investigates the resonant effects in nonlinear photon absorption in femtosecond laser ablation of Nd-doped silicate glass (Nd:glass). During the femtosecond laser ablation process, the resonant ablation threshold fluence is decreased by up to 40% compared with that of ordinary ablation. However, it is found that the resonant effect ...
Kudsi Omar Yusef - - 2012
BACKGROUND: It has been hypothesized that alcohol metabolism is altered after weight-loss surgery (WLS), with a few studies suggesting a high prevalence of postoperative problem drinking. However, many of these studies were methodologically limited by lack of preoperative alcohol use data, high loss to follow-up, and/or nonsystematic ascertainment of alcohol ...
Andersen E S - - 2012
Variations in bladder position, shape and volume cause uncertainties in the doses delivered to this organ during a course of radiotherapy for pelvic tumors. The purpose of this study was to evaluate the potential of dose accumulation based on repeat imaging and deformable image registration (DIR) to improve the accuracy ...
Pina M Fatima - - 2012
Paroxetine hydrochloride (HCl) is an anti-depressant drug, reported to exist in the anhydrous form (Form II) and as a stable hemihydrate (Form I). In this study, we investigate the hydration behaviour of paroxetine HCl Form II with a view to understanding both the nature of the interaction with water and ...
Han Rongfei - - 2012
The epithelial-mesenchymal transition (EMT) is a fundamental process governing morphogenesis in multicellular organisms and has recently been implicated in promoting carcinoma invasion and metastasis. Besides their therapeutic effects, accumulating evidences suggest that chemotherapeutic agents also induced EMT and enhanced the malignancy of treated cancer cells; however, the mechanism(s) still remains ...
McDonald S D - - 2012
AIMS: Compared with women with uncomplicated pregnancies, women with a history of pre-eclampsia have two to five times the risk of cardiovascular disease. It is not known whether this risk is related to albuminuria, a known cardiovascular risk factor that is part of the definition of pre-eclampsia and that often ...
Pedrero Zoyne - - 2012
Microbial activity is recognised to play an important role on Hg methylation in aquatic ecosystems. However, the mechanism at the cellular level is still poorly understood. In this work subcellular partitioning and transformation of Hg species in two strains: Desulfovibrio sp. BerOc1 and Desulfovibrio desulfuricans G200 (which exhibit different Hg ...
Loko Marc-Arthur - - 2012
BACKGROUND: The aim of this study was to describe changes in repeated liver stiffness (LS) measurements and to assess the determinants of increase in LS in HIV-HCV-coinfected patients. METHODS: HIV-HCV-coinfected adults enrolled in the ANRS CO 13 HEPAVIH cohort, for whom two results of LS, evaluated over ≥24 months, were ...
Williams Leslie K - - 2012
The increasing prevalence of diabetes has accelerated the search for new drugs derived from natural sources. To define the functional features of two such families of compounds, the flavonols and the ethyl caffeates, we have determined the high-resolution structures of representative inhibitors in complex with human pancreatic α-amylase. Myricetin binds ...
Breton Daniel James - - 2012
We describe a microcontroller-based ice core melting and data logging system allowing simultaneous depth co-registration of a continuous flow analysis (CFA) system (for microparticle and conductivity measurement) and a discrete sample analysis system (for geochemistry and microparticles), both supplied from the same melted ice core section. This hybrid melting system ...
Zhao Shuangshuang - - 2012
In this paper, an optical accelerometer based on grating interferometer with phase modulation technique is proposed. This device architecture consists of a laser diode, a sensing chip and an optoelectronic processing circuit. The sensing chip is a sandwich structure, which is composed of a grating, a piezoelectric translator and a ...
Häkli Sanna - - 2012
The age at onset and the severity of hearing impairment (HI) varies widely among subjects and within families with the m.1555A>G mutation in mitochondrial DNA. We examined prospectively the hearing of 19 children in three nuclear families of a pedigree with m.1555A>G during a period of 7.8 years. The children ...
Ismail Z - - 2012
Descemet membrane detachment (DMD) is a rare but potentially serious surgical complication that arises most often during cataract surgery. A recent study (Couch, S. M. & Baratz, K. H. (2009) Cornea, 28, 1160-1163) cited the case of a patient with DMDs in both eyes, noting that though one detachment was ...
Stahl Wilhelm - - 2012
Protection against skin damage from sunlight by nutritional means has been examined. Likewise, there has been work on the topical application of phytochemicals to the skin. This review focuses on the nutritional aspect of phytochemicals in humans-ie, the provision of carotenoid micronutrients by dietary means to the skin and their ...
Mori Issei - - 2012
When too few photons reach detector elements, strong streaks appear through paths of high X-ray attenuation and an image becomes completely useless. This photon starvation artifact phenomenon occurs frequently when a pelvis or shoulder is scanned with thin slices. The common understanding regarding photon starvation streaks is that they are ...
Ogbuanu Chinelo - - 2012
We examined factors associated with children's access to quality health care, a major concern in Georgia, identified through the 2010 Title V Needs Assessment. Data from the 2007 National Survey of Children's Health were merged with the 2008 Area Resource File and Health Resources and Services Administration medically underserved area ...
Chitcholtan Kenny - - 2012
The structure and function of membrane-wall attachment sites in walled cells, and how these relate to animal focal adhesions, is an area that is poorly understood. In view of this, we investigated how membrane-wall attachments that form upon plasmolysis, respond to peptides that disrupt animal focal adhesions. The degree of ...
Guan Zheng-Hui - - 2012
A Pd-catalyzed regioselective C-H bond carbonylation of N-alkyl anilines for the synthesis of isatoic anhydrides has been developed. The key Pd-catalyst intermediate has been isolated and characterized. This novel Pd-catalyzed carbonylation reaction tolerates a wide range of functional groups and is a reliable method for the rapid elaboration of readily ...
Agmon-Levin Nancy - - 2012
The elevated cardiovascular morbidity in rheumatoid arthritis, systemic lupus erythematosus, and the antiphospholipid syndrome is well known, as well as the pulmonary involvement observed in these conditions and to a major extent in systemic sclerosis. These manifestations constitute a major challenge for clinicians involved in patient management. Moreover, several issues ...
Coco Daniela - - 2012
A novel soybean-infecting begomovirus from Brazil was identified in Jaíba, in the state of Minas Gerais, and molecularly characterized. By using rolling-circle amplification-based cloning of viral DNAs, three DNA-A variants and a cognate DNA-B were isolated from infected samples. The DNA variants share more than 98 % sequence identity but have ...
Ganesan Latha P - - 2012
It has long been known that the ITIM-bearing IgG Fc receptor (FcγRIIb, RIIb) is expressed on liver sinusoidal endothelial cells (LSEC) and that the liver is the major site of small immune complex (SIC) clearance. Thus, we proposed that RIIb of LSEC eliminates blood-borne SIC, thereby controlling immune complex-mediated autoimmune ...
Sisler Jeffrey J - - 2012
PURPOSE: This study examines at a population level how colorectal cancer (CRC) survivors evaluate the continuity and quality of their follow-up care after treatment, particularly for those in the care of a primary care provider (PCP). METHODS: A survey was mailed in 2010 to all individuals in Manitoba, Canada diagnosed ...
Ng Chee-Hoe - - 2012
Mutations in parkin and LRRK2 together account for the majority of familial Parkinson's disease (PD) cases. Interestingly, recent evidence implicates the involvement of parkin and LRRK2 in mitochondrial homeostasis. Supporting this, we show here by means of the Drosophila model system that, like parkin, LRRK2 mutations induce mitochondrial pathology in ...
Timsit Edouard - - 2012
Mycoplasma bovis is an important cause of bovine respiratory disease (BRD) in newly received cattle at fattening operations. However, little information on its within-pen transmission dynamics during a BRD outbreak is available. Such information is nevertheless crucial to adapt control measures during M. bovis-associated BRD outbreaks. The objective of the ...
Paraknowitsch Jens Peter - - 2012
Carbon materials that are intrinsically co-doped with nitrogen and sulfur heteroatoms are synthesised by facile annealing of nitrile-functionalised thiazolium salts. Extremely high degrees of doping are achieved, especially for sulfur. The method further allows for direct tuning of the amounts of both N and S, establishing a new synthetic pathway ...
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