Search Results
Results 601 - 650 of 5601
< 8 9 10 11 12 13 14 15 16 17 18 >
Maia Berta R - - 2012
The role of perfectionism as a correlate and as a predictor of perinatal depressive symptomatology and disorder was examined. Three-hundred and eighty-six pregnant women (mean age = 30.08 years; SD = 4.205; range = 19-44) completed the Portuguese versions of the Multidimensional Perfectionism Scale, Beck Depression Inventory-II/BDI-II and three questions evaluating anxiety trait, life stress and social ...
Lütgendorf-Caucig C - - 2012
BACKGROUND AND PURPOSE: In pediatric Hodgkin's lymphoma (PHL) improvements in imaging and multiagent chemotherapy have allowed for a reduction in target volume. The involved-node (IN) concept is being tested in several treatment regimens for adult Hodgkin's lymphoma. So far there is no consensus on the definition of the IN. To ...
Hesse Daniela - - 2012
Chronic otitis media is a common disease often accompanied by recurrent bacterial infections. These may lead to the destruction of the middle ear bones such that prostheses have to be implanted to restore sound transmission. Surface coatings with layered double hydroxides (LDHs) are evaluated here as a possibility for drug ...
Halvorsen Michele B MB Pacific Northwest National Laboratory, Marine Sciences Laboratory, Sequim, WA 98382, - - 2012
Pile-driving and other impulsive sound sources have the potential to injure or kill fishes. One mechanism that produces injuries is the rapid motion of the walls of the swim bladder as it repeatedly contacts nearby tissues. To further understand the involvement of the swim bladder in tissue damage, a specially ...
Allentoft Morten E ME Ancient DNA Laboratory, School of Biological Sciences and Biotechnology, Murdoch University, 90 South Street, Perth, Western Australia 6150, Australia. - - 2012
Claims of extreme survival of DNA have emphasized the need for reliable models of DNA degradation through time. By analysing mitochondrial DNA (mtDNA) from 158 radiocarbon-dated bones of the extinct New Zealand moa, we confirm empirically a long-hypothesized exponential decay relationship. The average DNA half-life within this geographically constrained fossil ...
Perdigão João - - 2012
OBJECTIVES: The development and transmission of extensively drug-resistant (XDR) tuberculosis (TB) constitutes a serious threat to the effective control of TB in several countries. Here, in an attempt to further elucidate the dynamics of the acquisition of resistance to second-line drugs and investigate an eventual role for eis promoter mutations ...
Kumar Sukhbinder S Institute of Neuroscience, Medical School, Newcastle University, Newcastle upon Tyne, NE2 4HH, United Kingdom. - - 2012
This study addresses the neuronal representation of aversive sounds that are perceived as unpleasant. Functional magnetic resonance imaging in humans demonstrated responses in the amygdala and auditory cortex to aversive sounds. We show that the amygdala encodes both the acoustic features of a stimulus and its valence (perceived unpleasantness). Dynamic ...
Zhou Huijuan - - 2012
A single-mode Brillouin-erbium fiber laser (BEFL) is realized using only a 5 m single-mode fiber (SMF) as Brillouin gain medium, which to our best knowledge is the shortest SMF ever used to construct a BEFL. The Brillouin pump (BP) preamplification technique is adopted using a bidirectionally amplified erbium-doped fiber amplifier inside ...
Sharoni Yoav - - 2012
Evidence from epidemiologic studies has suggested that carotenoids, and lycopene in particular, decrease the risk of cancer: however, not all studies support this view. To gain insight into the molecular mechanisms whereby lycopene and other carotenoids may exert their chemoprotective effects, we and others performed a series of studies that ...
Ramos-Cordoba Eloy - - 2012
The decomposition of ⟨Ŝ(2)⟩ for a general wave function has been carried out in the framework of the Hilbert-space analysis. The one and two-center components fulfill all physical requirements imposed to date. An inherent ambiguity of the Hilbert-space decomposition of a two-electron quantity, in particular using a Mulliken-type scheme, is ...
Altmann Annette - - 2012
The ubiquitin-proteasome pathway has been identified as a potential molecular target for cancer therapy. In this study, we investigated the effect of the proteasome inhibitor bortezomib on anaplastic thyroid carcinoma (ATC) characterized by complete refractoriness to multimodal therapeutic approaches. METHODS: The ATC cell lines C643 and SW1736 were treated with ...
Erol Erdal - - 2012
Nocardioform actinomycetes are significant causes of placentitis and abortions in horses. In the current study, antimicrobial susceptibility patterns of 38 Amycolatopsis spp. and 22 Crossiella equi isolates, the most common nocardioform actinomycetes causing placentitis in horses, were evaluated. Antimicrobial susceptibilities of these isolates were tested by broth microdilution method in ...
Lan Xiaolan - - 2012
Oscillating chemiluminescence enhanced by the addition of tri-n-propylamine (TPrA) to the typical Belousov-Zhabotinsky (BZ) reaction system catalyzed by ruthenium(II)tris(2.2'-bipyridine)(Ru(bpy)(3) (2+) ) was investigated using a luminometry method. The [Ru(bpy)(3) ](2+) /TPrA system was first used as the catalyst for a BZ oscillator in a closed system, which exhibited a shorter ...
Poonawalla Aziz H AH Department of Radiology, University of Wisconsin, Madison, Wisconsin 53792-3252, - - 2013
To validate adipose tissue magnetic resonance imaging (atMRI) for rapid, quantitative volumetry of visceral adipose tissue (VAT) and total adipose tissue (TAT). Data were acquired on normal adults and clinically overweight girls with Institutional Review Board (IRB) approval/parental consent using sagittal 6-echo 3D-spoiled gradient-echo (SPGR) (26-sec single-breath-hold) at 3T. Fat-fraction ...
Zaferanloo Bita - - 2012
Endophytes are microorganisms that live within plant tissues that are potential sources of novel bioactive compounds, including enzymes. We have identified endophytes of the Australian native plant Eremophilia longifolia which were screened for the production of industrially useful enzymes. Seventeen fungal endophytes were isolated from the leaves of E. longifolia ...
Rapley P L - - 2012
Recent research in cell biology as well as oncology research has focused on apoptosis or programmed cell death as a means of quantifying the induced effects of treatment. A hallmark of late-stage apoptosis is nuclear fragmentation in which DNA is degraded to release nucleosomes with their associated histones. In this ...
Ottaviani Donatella - - 2012
We investigated the virulence properties of four Vibrio parahaemolyticus strains causing acute gastroenteritis following consumption of indigenous mussels in Italy. The isolated strains were cytotoxic and adhesive but, surprisingly, lacked tdh, trh, and type three secretion system 2 (T3SS2) genes. We emphasize that nontoxigenic V. parahaemolyticus can induce acute gastroenteritis, ...
Tavares Luiz F D - - 2012
Biosurfactants are a class of functional molecules produced and secreted by microorganisms, which play important roles in cell physiology such as flagellum-dependent or -independent bacterial spreading, cell signaling, and biofilm formation. They are amphipathic compounds and comprise a variety of chemical structures, including rhamnolipids, typically produced by Pseudomonas spp. and ...
Błachnio-Zabielska Agnieszka U - - 2012
Obesity is a risk factor for metabolic diseases. Intramuscular lipid accumulation of ceramides, diacylglycerols, and long chain acyl-CoA is responsible for the induction of insulin resistance. These lipids are probably implicated in obesity-associated insulin resistance not only in skeletal muscle but also in fat tissue. Only few data are available ...
D'Abreu Lylla Cysne Frota - - 2012
Despite the increased attention devoted to sexual aggression among college students in the international research literature, Brazil has no systematic studies on the prevalence of sexual aggression in college populations. The present research measured the prevalence of sexual aggression and victimization since age 14 among 742 first-year college students in ...
Berndt Rolf-Dietrich - - 2012
Abstract Objective: The increasing number of elderly and chronically ill patients is currently stressing healthcare systems. One of the solutions for reaching an economically and socially viable solution is exploiting the benefits of modern technologies. This article presents an innovative mobile teledermatology program for assisting both the therapy and the ...
Tognini Sara - - 2012
Conflicting data are reported on the association between mild thyroid failure and lipid profile, primarily regarding serum triglyceride values and patients with slightly elevated thyrotropin (TSH, <10 mIU/L). In this study, we assessed the possible influence of gender and age on this relationship. The study included 2308 consecutive patients who ...
Sun Jing - - 2012
A facile synthetic protocol was developed for the efficient synthesis of complex dispirooxindole-fused heterocycles via a three-component reaction. The key strategies involve a domino 1,4-dipolar addition and Diels-Alder reaction of the in situ generated Huisgen 1,4-dipoles from the addition reaction of 4-dimethylaminopyridine with acetylenedicarboxylate to 3-phenacylideneoxindole.
Sari Esin Sogutlu - - 2012
BACKGROUND: To evaluate the 3-year clinical outcomes after toric implantable collamer lens (ICL) implantation for the management of moderate to high myopic astigmatism. METHODS: Thirty-four eyes of 20 patients who underwent toric ICL implantation were reviewed. All eyes completed 3-year follow-up. Uncorrected (UDVA) and corrected (CDVA) distance LogMAR visual acuities, refraction, ...
Takekoshi Daisuke - - 2012
Mycobacterium chelonae, a species of rapidly growing mycobacteria, may grow in routine blood culture media and stain as gram-positive bacilli, which may cause diagnostic confusion. A patient with native-valve endocarditis caused by M. chelonae, which was misidentified as various gram-positive bacilli, is presented.
He Weiyang W Department of Urology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, - - 2012
Although it is known that tumor necrosis factor-related apoptosis-inducing ligand (TNFSF10/TRAIL) induces autophagy, the mechanism by which autophagy is activated by TNFSF10 is still elusive. In this report, we show evidence that TRAF2- and RIPK1-mediated MAPK8/JNK activation is required for TNFSF10-induced cytoprotective autophagy. TNFSF10 activated autophagy rapidly in cancer cell ...
Bien Christian G - - 2012
BACKGROUND: Presurgical epilepsy diagnostics and surgical treatment have become standard procedures of neurology. Here, we report on presurgical patients grouped according to their underlying pathology by giving results of presurgical evaluation, surgical therapy and long-term follow-up between 1989-2009 and describe trends over this period. PATIENTS AND METHODS: Data of prospectively ...
Klug Achim A Department of Physiology and Biophysics, University of Colorado School of Medicine, Aurora, Colorado 80045, USA. - - 2012
Synaptic transmission is highly dependent on recent activity and can lead to depression or facilitation of synaptic strength. This phenomenon is called "short-term synaptic plasticity" and is shown at all synapses. While much work has been done to understand the mechanisms of short-term changes in the state of synapses, short-term ...
Bhagat Rahul - - 2012
PURPOSE: Tumor suppressor gene (TSG) silencing through promoter hypermethylation plays an important role in cancer development. The aim of this study was to assess the extent of methylation of the RASSF1A and APC TSG promoters in ovarian epithelial adenomas, low malignant potential tumours and carcinomas in order to reveal a ...
Ramakrishnan Vijay R - - 2012
BACKGROUND: Chronic rhinosinusitis (CRS) is an idiosyncratic and multifactorial disease process. Bacteria play a role in some patients, by infection or stimulation of inflammation. Staphylococcus aureus (SA) appears to be implicated in a number of infectious and inflammatory mechanisms, and may be particularly relevant in CRS patients with nasal polyps ...
Dodurga Yavuz Y Department of Medical Biology, School of Medicine, Pamukkale University, Kinikli Kampusu Morfoloji Binasi Kat:3 Kinikli, Denizli, Turkey. - - 2012
Hepatocellular carcinoma (HCC) originates from liver cells and is one of the most common malignant cancers in the world. microRNAs (miRNA), are single strand non-coding RNA molecules with the length of 18-25 nucleotides. miRNAs play an important role in the development of HCC, i.e., miRNAs have a significant impact on ...
Dai Zhichu - - 2012
SUMMARY AT A GLANCE: A retrospective cohort study of non-neutropenic patients who had been diagnosed with IPA at our institution over the last 10 years was conducted to investigate epidemiology, clinical characteristics, outcomes, prognosis and survey the difference between non-neutropenic patients with and without underlying diseases. ABSTRACT: Background and Objective:  ...
Soma Junichi - - 2012
Rotavirus C (RVC) has been frequently detected in epidemic cases and/or outbreaks of diarrhea in humans and animals worldwide. Because it is difficult to cultivate RVCs serially in cell culture, available sequence date of RVCs are limited despite their potential economical and epidemiological impact. Although whole-genome sequences of one porcine ...
Okiror Lawrence - - 2012
Meningiomas are tumours arising from the meninges that ensheath the central nervous system. They are benign tumours, but can very rarely metastasize. We report a case of pulmonary meningioma diagnosed incidentally with concurrent brain masses in an ex-smoker and discuss the difficulties in surgical decision making in a mass that ...
De Deyne Simon - - 2012
In this article, we describe the most extensive set of word associations collected to date. The database contains over 12,000 cue words for which more than 70,000 participants generated three responses in a multiple-response free association task. The goal of this study was (1) to create a semantic network that ...
Murphy Sean C - - 2012
Dried blood spots (DBS) are useful for molecular assays but are prone to false positives from cross-contamination. In our malaria DBS assay, cross-contamination was encountered despite cleaning techniques suitable for HIV-1. We therefore developed a contact-free laser cutting system that effectively eliminated cross-contamination during DBS processing.
Zubin Maslov Petra - - 2012
Premature ventricular contractions (PVC) elicit larger bursts of multi-unit muscle sympathetic nerve activity (MSNA) reflecting the ability to increase postganglionic axonal recruitment. We tested the hypothesis that chronic heart failure (CHF) limits the ability to recruit postganglionic sympathetic neurons as a response to PVC due to the excessive sympathetic activation ...
Lalko Jon F - - 2012
It is well established that certain chemicals cause respiratory allergy. In common with contact allergens, chemicals that induce sensitization of the respiratory tract must form stable associations with host proteins to elicit an immune response. Measurement of the reactivity of chemical allergens to single nucleophilic peptides is increasingly well-described, and ...
Chen Rong - - 2012
Conventional sol-gel processing requires several distinct steps involving hydrolysis, condensation and drying to obtain a highly porous, glassy solid material. With the goal of achieving controlled release of small molecules, herein we focus on the acceleration of the condensation and drying steps by casting the hydrolyzed sol on a large ...
Chatzimpaloglou Anthoula - - 2012
The total synthesis of the structure assigned to the natural product phaeosphaeride A 1a was accomplished. The key steps involve the addition of vinyllithium reagent 7 to the acetonide-protected aldehyde 8 to access the carbon backbone of 1a, the introduction of methoxylamino group followed by intramolecular hetero-Michael cyclization and methanol ...
Emery Andrew C AC National Institute of Mental Health, 49 Convent Drive, Building 49, Room 5A-38, Bethesda, MD 20892-4090, - - 2013
We evaluated the efficacy, potency, and selectivity of the three most commonly used adenylate cyclase (AC) inhibitors in a battery of cell lines constructed to study signaling via three discrete cAMP sensors identified in neuroendocrine cells. SQ22,536 [9-(tetrahydrofuryl)-adenine] and 2',5'-dideoxyadenosine (ddAd) are effective and potent AC inhibitors in HEK293 cells ...
Wei Liping - - 2012
A new synthesis of γ-rubromycin is presented through a new oxidative, bisbenzannulated spiroketalization as a key step which is catalyzed by an in situ generated hypoiodite species, developed previously by our group. This key transformation has high efficiency and convenient conditions. This is a new and efficient catalytic application for ...
Franco Edgar F Mendoza - - 2012
As part of a biological inventory of the Rio Lacantún basin in the Biosphere Reserve of Montes Azules from Chiapas State (southeastern, Mexico), the following monogenoid ectoparasites infecting the external surface of the anal opening and the gill lamellae of the freshwater fish Astyanax aeneus (Characidae) in ten streams were ...
Teng Yun Y Department of Biochemistry & Molecular Biology and Center for Genetics and Molecular Medicine, University of Louisville School of Medicine, Louisville, Kentucky 40292, - - 2013
Fenhexamid and fludioxonil are antifungal agents used in agricultural applications, which are present at measurable amounts in fruits and vegetables. Fenhexamid and fludioxonil showed endocrine disruptor activity as antiandrogens in an androgen receptor reporter assay in engineered human breast cancer cells. Little is known about how environmental chemicals regulate microRNA ...
Funatsu T - - 2012
We evaluated the relationship between antithrombotic effects and pharmacodynamic (PD) marker changes produced by the novel factor (F)Xa inhibitors darexaban (YM150) and rivaroxaban in a rabbit model of plaque disruption-induced arterial thrombosis. Animals were subjected to catheter-induced endothelial denudation via the femoral artery followed by a two-week high-cholesterol diet. Plaque ...
King Gordon J GJ Institute for Molecular Bioscience, University of Queensland, Brisbane, Queensland 4072, - - 2012
The APPL1 and APPL2 proteins (APPL (adaptor protein, phosphotyrosine interaction, pleckstrin homology (PH) domain, and leucine zipper-containing protein)) are localized to their own endosomal subcompartment and interact with a wide range of proteins and small molecules at the cell surface and in the nucleus. They play important roles in signal ...
Antonica Francesco - - 2012
The primary function of the thyroid gland is to metabolize iodide by synthesizing thyroid hormones, which are critical regulators of growth, development and metabolism in almost all tissues. So far, research on thyroid morphogenesis has been missing an efficient stem-cell model system that allows for the in vitro recapitulation of ...
Hernando Diego D Department of Radiology, University of Wisconsin, Madison, Wisconsin 53705, USA. - - 2013
To investigate R2* mapping robustness in the presence of fat using in-phase echoes, without and with spectral modeling of fat (single-peak and multipeak models, respectively), using varying numbers of echoes. Data from 88 volunteers (men/women: 52/36, ages: 55.4 ± 12.2) were randomly chosen according to magnetic resonance imaging (MRI) liver ...
Ly Donald L DL Keenan Research Centre in the Li Ka Shing Knowledge Institute, St. Michael’s Hospital and Department of Surgery, University of Toronto, Ontario, - - 2013
Hyperosmotic stress initiates several adaptive responses, including the remodeling of the cytoskeleton. Besides maintaining structural integrity, the cytoskeleton has emerged as an important regulator of gene transcription. Myocardin-related transcription factor (MRTF), an actin-regulated coactivator of serum response factor, is a major link between the actin skeleton and transcriptional control. We ...
Sundararajan Lakshmi L Programs in Genetics and Molecular, Cellular, and Developmental Biology, Department of Molecular Biosciences, University of Kansas, Lawrence, KS 66045, - - 2012
Migration of neurons and neural crest cells is of central importance to the development of nervous systems. In Caenorhabditis elegans, the QL neuroblast on the left migrates posteriorly, and QR on the right migrates anteriorly, despite similar lineages and birth positions with regard to the left-right axis. Initial migration is ...
< 8 9 10 11 12 13 14 15 16 17 18 >