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Results 551 - 600 of 5599
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Ito Shuichi - - 2012
BACKGROUND: Rituximab (RTX) is a promising option for treating childhood-onset steroid-dependent (SDNS), frequently relapsing (FRNS), and steroid-resistant (SRNS) nephrotic syndrome. METHODS: We retrospectively surveyed RTX treatment for these conditions to evaluate its indications, efficacy and adverse events. Questionnaires were sent to 141 hospitals in Japan. RESULTS: Seventy-four patients (52 SDNS; ...
Anckaert Ellen - - 2012
BACKROUNDFollicle culture and oocyte in vitro maturation (IVM) are emerging assisted reproductive technologies with potentially important future applications in the fertility clinic. There is concern that these technologies might interfere at the epigenetic level and, in particular, with genomic imprinting. The timely acquisition of correct imprinting patterns in oocytes and ...
Guerron Alfredo D - - 2012
BACKGROUND: Findings have shown laparoscopic liver resection (LLR) to be feasible and safe, but the data in the literature regarding oncologic outcomes are scant. This study aimed to compare the perioperative and short-term oncologic outcomes between LLR and open resection of colorectal liver metastasis (CLM). METHODS: Between January 2006 and ...
Trost Barry M - - 2012
Here it goes again: A tandem catalytic process that effects sequential Pd(0) -catalyzed allylic alkylations through leaving group ionization and Pd(II) -catalyzed allylic alkylations by CH activation is reported. By employing an oxidative trigger to convert the catalytic species from Pd(0) to Pd(II) , both transformations can be conducted in ...
Liu Xiaonao - - 2012
We describe an ink-jet printing assisted cooperative-assembly method for high-throughput generation of catalyst libraries (multi-component mesoporous metal oxides) at a rate of 1,000,000-formulations/hour with up to eight-component compositions. The compositions and mesostructures of the libraries can be well controlled and continuously varied. Fast identification of an inexpensive and efficient quaternary ...
Berhouma Moncef - - 2012
BACKGROUND: Since the introduction of the endoscopic endonasal approaches in the field of skull base surgery during the last two decades, several variants of the sella turcica endoscopic surgery have been described. The aim of this study is to provide a stepwise description of one of these variants in a ...
Heußner P - - 2012
The relationships between the psyche and cancer are manifold. Psycho-oncology focuses on the psychological adjustment to life-threatening illnesses. Crises are not unusual in health care, but the perception of cancer is totally different because the diagnosis of cancer often results in an irrational shock reaction in all parties involved. A ...
Krasovsky Tal - - 2012
Falls during walking are a major cause of injury in post-stroke individuals, and walking faster may further decrease gait stability. We compared gait stability between high-functioning post-stroke individuals and controls at matched speeds. We also evaluated the effect of a speed increase on gait stability in post-stroke individuals. Ten stroke ...
Trotman Carroll-Ann E - - 2012
Objectives :  (1) To collect three-dimensional, dynamic facial images from two groups of infants: one group born with cleft lip and palate slated to have a primary lip repair and a second, age-matched, noncleft control group. (2) To develop analyses to determine differences in facial movement between infants with cleft ...
Nguyen Khiem Van - - 2012
Present-day organisms are under constant environmental stress that damages bases in DNA, leading to mutations. Without DNA repair processes to correct these errors, such damage would be catastrophic. Organisms in all kingdoms have repair processes ranging from direct reversal to base excision and nucleotide excision repair, and the recently characterized ...
Tofighi Sara - - 2012
In this paper we study the optical bistability in a double coupler fiber ring resonator which consists of an erbium doped fiber amplifier (EDFA) in half part of the fiber ring and a quantum dot doped fiber (QDF) saturable absorber in the other half. The bistability is provided by the ...
Kreis Julia - - 2012
In the United States and internationally, the trend for public engagement in health policy and practice is increasing, particularly regarding health technology assessment (HTA), which informs often controversial coverage decisions. However, there is no consensus about which members of the public should be involved in which processes or what the ...
Jain Richa - - 2012
Superior Vena Cava Syndrome (SVCS) refers to signs and symptoms caused by obstruction of the superior vena cava. Superior mediastinal syndrome (SMS) is the term used when SVCS coexists with obstruction of trachea. In children, a mediastinal pathology causing SVCS generally results in SMS as well, due to the limited ...
Huang Hui - - 2012
In this paper, one-dimensional (1D) mesoporous single-crystalline Co3O4 nanobelts are synthesized by a facile hydrothermal method followed by calcination treatment. The as-prepared nanobelts have unique mesoporous structures, which are constructed by many interconnected nanocrystals with sizes of about 20-30 nm. And typical size of the nanobelts is in the range ...
Ogouyèmi-Hounto A - - 2012
The aim of the study was to determine the accuracy of a rapid diagnostic test (SD Bioline Malaria Ag P.f/ Pan®) and fluorescent microscopy (CyScope®) in confirming presumptive malaria diagnosis in Cotonou. Thick blood smear was used as the reference technique for comparison. Testing was conducted on persons between the ...
Monico Letizia - - 2012
Previous investigations about the darkening of chrome yellow pigments revealed that this form of alteration is attributable to a reduction of the original Cr(VI) to Cr(III) and that the presence of sulfur-containing compounds, most often sulfates, plays a key role during this process. We recently demonstrated that different crystal forms ...
Fijlstra Margot - - 2012
It is unknown what feeding strategy to use during chemotherapy-induced gastrointestinal mucositis, which causes weight loss and possibly malabsorption. To study the absorptive capacity of amino acids during mucositis, we determined the plasma availability of enterally administered amino acids (AA), their utilization for protein synthesis, and the preferential side of ...
Gao Hongli - - 2012
Yerba Mate tea (Mate) is believed to be a natural source of cardioprotective lipid-lowering and antioxidant compounds. In this study, the antihyperlipidemic and antioxidant effects of Mate tea in a rat hyperlipidemia model were investigated. Male Sprague-Dawley rats were divided randomly into five groups and fed varying diets: standard diet, ...
Leja Chris - - 2012
Lasers have been proposed for various applications involving dental implants, including uncovering implants and treating peri-implantitis. However, the effect of laser irradiation on the implant surface temperature is only partially known. The aim of this pilot study was to determine the effect of irradiation with diode, carbon dioxide, and Er:YAG ...
Kim Tark - - 2012
R-CHOP chemotherapy composed of rituximab, cyclophosphamide, adriamycin, vincristine, and prednisolone which might increase the risk of Pneumocystis pneumonia in patients with non-Hodgkin lymphoma. We estimated the point prevalence of Pneumocystis pneumonia in non-Hodgkin lymphoma patients according to the number of R-CHOP cycles and investigated whether cytoreduction by chemotherapy is associated ...
Menger-Krug Eve Katrin - - 2012
Integrating microalgae systems (MAS) at municipal wastewater treatment plants (WWTPs) to produce of bio energy offers many potential synergies. Improved energy balances provide a strong incentive for WWTPs to integrate MAS, but it is crucial that WWTPs maintain their barrier function to protect water resources. We perform a prospective analysis ...
de Leon Erich E - - 2012
Confocal microscopy rejects out-of-focus light from the object by scanning a pinhole through the image and reconstructing the image point by point. Volume holographic imaging systems with bright-field illumination have been proposed as an alternative to conventional confocal-type microscopes that does not require scanning of a pinhole or a slit. ...
Tang Guangwen - - 2012
Dietary β-carotene is the most important precursor of vitamin A. However, the determination of the efficiency of in vivo conversion of β-carotene to vitamin A requires sensitive and safe techniques. It presents the following challenges: 1) circulating β-carotene concentration cannot be altered by eating a meal containing ≤6 mg β-carotene; ...
Zhao Guo-Yang - - 2012
Bone metabolism has a close relationship with iron homeostasis. To examine the effects of iron excess and iron deficiency on the biological activities of osteoblast in vitro, human osteoblast cells (hFOB1.19) were incubated in a medium supplemented with 0-200 μmol/L ferric ammonium citrate and 0-20 μmol/L deferoxamine. The intracellular iron was measured ...
Lu Yi-Qun - - 2012
This study aims to explore the effect of advanced glycosylation end products (AGEs) on proliferation of human bone marrow mesenchymal stem cells in vitro and the underlying mechanism. Bone marrow cell proliferation was determined by WST-8 assay using Cell Counting Kit-8 under the intervention of AGEs. In addition, the content ...
Wei Meiying - - 2012
A bis-bisurea receptor () based on the R,R-cyclohexane-1,2-diamino scaffold forms an uncommon 2 : 2 complex () with the monohydrogen phosphate ion (HPO(4)(2-)) and a 1 : 1 complex () with the sulfate ion (SO(4)(2-)). Solution binding properties of the two anions were studied by (1)H NMR, UV-vis, and circular dichroism (CD) methods.
Yu Dayu - - 2012
A putative indigoidine biosynthetic gene cluster was located in the genome of Streptomyces chromofuscus ATCC 49982. The silent 9.4-kb gene cluster consists of five open reading frames, named orf1, Sc-indC, Sc-indA, Sc-indB, and orf2, respectively. Sc-IndC was functionally characterized as an indigoidine synthase through heterologous expression of the enzyme in ...
Fernandes Rita Lencastre - - 2012
Despite traditionally regarded as identical, cells in a microbial cultivation present a distribution of phenotypic traits, forming a heterogeneous cell population. Moreover, the degree of heterogeneity is notably enhanced by changes in micro-environmental conditions. A major development in experimental single-cell studies has taken place in the last decades. It has ...
Höffner K - - 2012
Dynamic flux balance analysis (DFBA) provides a platform for detailed design, control and optimization of biochemical process technologies. It is a promising modeling framework that combines genome-scale metabolic network analysis with dynamic simulation of the extracellular environment. Dynamic flux balance analysis assumes that the intracellular species concentrations are in equilibrium ...
Zhang Jing - - 2012
SUMMARY AT A GLANCE: This study showed that underdiagnosis and undertreatment of COPD remains substantial in lung cancer patients. Documentation of smoking history or respiratory symptoms promotes disease diagnosis. Education of COPD knowledge among patients and doctors and improvement of disease management are urgently required in this special population. ABSTRACT: ...
Stanilov Noyko S - - 2012
The main regulator of anti-tumor immune response is the activity of monocytes, suggesting that the produced cytokines may have a prognostic role. This study investigates gene expression of interleukin (IL)-12-related cytokine and IL-10 in stimulated monocytes from colorectal cancer (CRC) patients. Relative quantification of IL-12A, IL-12B, IL-23A and IL-10 mRNA ...
Sonneville Romain - - 2012
OBJECTIVES: Cerebral toxoplasmosis remains a common neurologic complication in patients with AIDS. In this study, we aimed to characterize the prognosis of patients with HIV infection with severe forms of cerebral toxoplasmosis and to investigate the effects of adjunctive steroids on outcomes. METHODS: We carried out a retrospective cohort study ...
Goldstein Ido - - 2012
Cytochrome P450 enzymes (P450) are abundantly expressed in the human liver where they hydroxylate organic substrates. In a microarray screen performed in human liver cells, we found a group of eleven P450 genes whose expression was induced by p53 (CYP3A4, CYP3A43, CYP3A5, CYP3A7, CYP4F2, CYP4F3, CYP4F11, CYP4F12, CYP19A1, CYP21A2 and ...
Wang Yinan - - 2012
To know the involvement of glycosaminoglycans (GAGs) in the metastasis of mouse FBJ osteosarcoma cells, N ( α )-lauroyl-O-(β-D-xylopyranosyl)-L-serinamide (Xyl-Ser-C12), which initiates elongation of GAG chains using the glycan biosynthesis system in cells, was administered to FBJ cells with different metastatic capacities. Production of glycosylated products derived from Xyl-Ser-C12, especially ...
Obeidat Basil R - - 2012
To assess the immuno-histochemical expression of various markers in, endometrial biopsies of patients with endometrial cancer, and to correlate their expression with the final pathologic findings. Sixty-two patients with primary endometrial cancer who underwent surgical treatment were included in this study. Immuno-histochemical expression of estrogen receptor (ER), progesterone receptor (PR), ...
Dey Sabita Brata - - 2012
The work addresses the issues of the ever-expanding demand of wide free spectral range (FSR) compatible integrated optic passive devices used in commercial communication systems like dense wavelength division multiplexing and a host of other applications. FSR expansion has been achieved by using the Vernier principle. The analysis has been ...
Xin Jingtao - - 2012
A stable and simple interferometric arrangement based on a Wollaston prism is designed to combine two helical beams into a polarization vortex (PV). Different modes of helical beams are generated by a spatial light modulator (SLM). Due to the flexibility of the SLM, PVs with different kinds of intensity distribution, ...
Florentin Jonathan - - 2012
The elimination of hepatitis C virus (HCV) in more than 50% of chronically infected patients by treatment with interferon-α (IFN-α) suggests that plasmacytoid dendritic cells (pDCs), major producers of IFN-α, play an important role in the control of HCV infection. However, despite large amounts of Toll-like receptor 7 (TLR7)-mediated IFN-α, ...
Khandelwal Hitesh - - 2012
With an increase in temperature, an unprecedented restoration of symmetry in the symmetry breaking excited state charge transfer is observed in a geminal pair of near-orthogonally connected perylenimide dimers. Such restoration of symmetry could be attributed to the interchromophoric planarization and/or loss of solvation asymmetry at elevated temperature resulting in ...
Ramesh Veera V E - - 2012
Herein, we report on the folding pattern observed in a synthetic peptide featuring two highly mutually dependent, yet strikingly dissimilar, closed networks of hydrogen-bonded rings that work in a cumulative fashion to stabilize the entire folded architecture of the peptide. Structural studies unequivocally suggest that disruption of any one of ...
Pessoa Clarice R M - - 2012
Cutaneous and rhinofacial infections by Pythium insidiosum have previously been reported in sheep in Brazil. In the current study, a new form of pythiosis involving the alimentary tract of 2 nursing lambs from 2 different farms in the semiarid region of Brazil is described. The first lamb showed food regurgitation, ...
Del Nogal María - - 2012
Renal fibrosis is the final outcome of many clinical conditions that lead to chronic renal failure, characterized by a progressive substitution of cellular elements by extracellular-matrix proteins, in particular collagen type I. The aim of this study was to identify the mechanisms responsible for human mesangial cell survival, conditioned by ...
Prescot Andrew P - - 2012
PURPOSE: To investigate human brain metabolite discriminability and general measurement reproducibility of two-dimensional (2D) J-resolved (1) H MRS and Prior Knowledge Fitting (ProFit). MATERIALS AND METHODS: 2D J-resolved (1) H MRS spectra were acquired from the anterior cingulate cortex (ACC) and the parietal-occipital cortex (POC) of 10 healthy subjects at ...
Hansson B M E - - 2012
BACKGROUND: Parastomal hernia is a frequent complication of intestinal stomata. Mesh repair gives the best results, with the mesh inserted via laparotomy or laparoscopically. It was the aim of this retrospective multicenter study to determine the early and late results of the laparoscopically performed, modified Sugarbaker technique with ePTFE mesh. ...
Hariri I - - 2012
Recent advances in the field of optics have enabled accurate and localized measurement of optical properties of biological substrates. This work aimed to elucidate the relationship between the local refractive index (n) and mineral content (MC) of enamel and dentin. De- and remineralized lesions in bovine enamel and dentin blocks ...
Boukari Khaoula - - 2012
We present a theoretical study in the framework of density functional calculations, taking into account the van der Waals interactions (DFT-D) of isolated Cu-5,10,15,20-tetrakis(3,5-di-tert-butyl-phenyl) porphyrin (Cu-TBPP) molecules in a C2v conformation adsorbed on a Si(111)√3x√3R30°-boron surface [denoted Si(111)-B]. With this approach, we investigate interactions between perfect or boron-defect Si(111)-B substrates ...
Rinne Juha O - - 2012
Molecular imaging techniques developed to 'visualize' amyloid in vivo represent a major achievement in Alzheimer's disease (AD) research. This pooled analysis of four studies determined the level of association between uptake of the fibrillar amyloid β positron emission tomography (PET) imaging agent [(18)F]flutemetamol (Pittsburgh Compound B analog with a 5.5 ...
Yao Hongjie - - 2012
Cinchona alkaloid-derived chiral quaternary ammonium organocatalysts were developed. The catalyst with a bulky 1-adamantoyl group at the C-9 position promoted the enantioselective α-hydroxylation of beta-oxo esters and resulted in the corresponding products in 35-95% yields and 58-90% ee. The reaction was successfully scaled to a gram-quantity scale with a similar ...
Smith Edith Caroline - - 2012
Hereditary breast and ovarian cancer syndrome is an inherited condition that women's health care providers are likely to encounter in their practices. Persons affected by this disorder have extremely high risks for developing cancer. This article provides a definition and overview of the syndrome, including cancer prevention/risk reduction strategies and ...
Singh Anand - - 2012
The [3 + 2] dipolar cycloaddition reaction of nitrile imines with 3-alkylidene oxindoles is described. The pyrazoline spiroadducts were obtained in high yields and with excellent regio- and diastereoselectivities. These spirocyclic intermediates have been elaborated to synthetically versatile 3-amino oxindole building blocks such as β-amino nitrile, 1,3-diamine, and pyrrolo[2,3-b]indoline derivatives.
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