Search Results
Results 551 - 600 of 5601
< 7 8 9 10 11 12 13 14 15 16 17 >
Uchida Hiroki - - 2012
PURPOSE: Surgical treatment of local recurrent papillary thyroid carcinoma is still controversial because of the increased morbidity in comparison to primary surgery, and the unclear efficacy. This study analyzed the efficacy and safety of surgery for recurrent disease. METHODS: A retrospective cohort analysis of 86 patients who underwent surgery for ...
Noor Rashed - - 2012
Emergence of extensively drug-resistant (XDR) tuberculosis (TB) in Bangladesh has increased as a result of the inadequate management of TB-infected individuals. The present study attempted to detect the frequency of multidrug resistance (MDR) among the TB patients categorically from relapse, category I failure, category II failure, and return after default ...
Akcalar Seray - - 2012
Lipomatosis is a benign and non-encapsulated mature form of fat tissue proliferation, which can be isolated or multiple, symmetrical or infiltrative, and may be associated with several syndromes. Lipomatosis has been reported to involve almost every part and organ in the body. In this review, we present imaging findings at ...
Zaarour Moussa - - 2012
The second order nonlinear optical (NLO) properties of various simple tris-cyclometallated Ir(iii) complexes bearing 2-phenylpyridine ligands have been investigated by means of the EFISH technique, evidencing how appropriate substitution of the cyclometallated ligands may allow the tuning of the second-order NLO response of this unusual family of 3D chromophores. To ...
Sanon Hadja Oumou - - 2012
The chemical composition, digestibility, and voluntary feed intake by sheep of mango by-products were studied in an experiment with five dietary treatments consisting of mango peels and seed kernels, offered individually or together with urea block and a control. The mango residues were offered with rice straw and the control ...
Tsai Jong-Rung - - 2012
BACKGROUND: Heme oxygenase-1 (HO-1), a rate-limiting enzyme in heme catabolism, is known to play a role in the protection of cells against oxidative stress, inflammation, anomalous proliferation and apoptosis. As yet, the role of HO-1 expression in non-small cell lung cancer (NSCLC) development and metastasis remains unclear and insufficient data ...
Wright Anthony G - - 2012
Drawing from ethnographic observations and interview data gathered during 6 months working as a home caregiver at the Pinewood Apartments, a recovery-oriented supported housing community in Texas, I demonstrate how stigma and social defeat were moral and social processes that pervaded life for all involved, including service providers. Yet, because of ...
Trojnar Eva - - 2012
Group A rotaviruses (RVAs) are an important cause of diarrhoeal illness in humans as well as in mammalian and avian animal species. Previous sequence analyses indicated that avian RVAs are only distantly related to mammalian RVAs. Here, the complete genomes of RVA strain 03V0002E10 from turkey (Meleagris gallopavo) and RVA ...
Zhao Chenghai - - 2012
Secreted Frizzled-Related Protein 5 (SFRP5) is frequently found downregulated in gastric cancer due to SFRP5 gene hypermethylation, and there is a great necessity to elucidate the role of its downregulation in gastric cancer. Via binding Wnt molecules, SFRP5 is generally supposed to exert negative effects on Wnt signal pathways widely ...
Ponsard Isabelle - - 2012
We demonstrated that an exogenous conjugate consisting of a β-lactamase and a monoclonal antibody against a surface antigen of Salmonella is capable of conferring selective penicillin resistance on bacteria. This immunoenzymatic approach allows the rapid growth and detection of specific bacteria and may find other applications when temporary and nongenetic ...
Smith Kimberly R KR Department of Psychology and Program in Neuroscience, Florida State University, Tallahassee, FL 32306-4301, - - 2012
In rodents, at least two transduction mechanisms are involved in salt taste: 1) the sodium-selective epithelial sodium channel, blocked by topical amiloride administration, and 2) one or more amiloride-insensitive cation-nonselective pathways. Whereas electrophysiological evidence from the chorda tympani nerve (CT) has implicated the transient receptor potential vanilloid-1 (TRPV1) channel as ...
Yadav Amarjeet - - 2012
Glutathione is an immensely important antioxidant, particularly in the central nervous system. The scavenging mechanism of glutathione towards the OH radical was studied theoretically, considering its neutral, non-zwitterionic form relevant to acidic media. Gibbs free barrier and released energies involved in hydrogen abstraction from the different sites of glutathione by ...
Wang Cun-Huan - - 2012
The static second-order nonlinear optical (NLO) properties on a series of the two-dimensional (2D) pincer Ru(II) complexes with the substituted Tpy and H(2)SCS tridentate ligands (Tpy = 2,2':6',2''-terpyridyl and H(2)SCS = 2,6-bis(benzylaminothiocarbonyl)phenyl) have been investigated by density functional theory (DFT). Introducing different donor/acceptor substituents to two ligands has an influence ...
Rockstroh Jürgen Kurt - - 2012
Early HIV therapy in HIV-HCV-coinfected individuals appears advisable in order to not only improve HIV outcome but also delay the natural course of liver disease. Indeed, antiretroviral-therapy-induced control of HIV infection with undetectable plasma HIV RNA levels affects HIV-HCV viral interactions and decreases liver inflammation resulting in lower fibrosis progression ...
Nicoletti A - - 2012
Serious cartilage lesions (Outerbridge III, IV) may be successfully treated with a three-layered gradient scaffold made by magnesium-doped hydroxyapatite and type I collagen, manufactured through a bio-inspired process and stabilised by a reactive bis-epoxy (1,4-butanediol diglycidyl ether, BDDGE). Each layer was analysed to elucidate the effects of crosslinking variables (concentration, ...
Murphy Patricia Aikins - - 2012
Emergency contraception (EC) is any method used after sexual intercourse to prevent pregnancy. This article provides an overview of the history of EC methods and describes the current availability of oral and intrauterine EC. Oral forms include the Yuzpe regimen (combining ethinyl estradiol and levonorgestrel), levonorgestrel-only pills, and ulipristal acetate, ...
Sozmen Fazli - - 2012
Bodipy dyes with integral phenanthroline and terpyridine units heteroleptically assemble in the presence of zinc(II) ions to form energy transfer cassettes. These discrete complexes exhibit an approach to modularly designed efficient energy transfer and light harvesting systems through metal ion coordination.
Shang Xiying - - 2012
Claudin-3 (CLDN3) and claudin-4 (CLDN4) are the major structural molecules that form tight junctions (TJs) between epithelial cells. We found that knockdown of the expression of either CLDN3 or CLDN4 produced marked changes in the phenotype of ovarian cancer cells including an increase in resistance to cisplatin (cDDP). The effect ...
Constanza Karen E - - 2012
To explore a potential use for peanut skins as a functional food ingredient, milled skins were extracted with 70% ethanol, filtered to remove insoluble material, and the soluble extract was spray dried with or without the addition of maltodextrin. Peanut skin extracts had high levels of procyanidin oligomers (DP2-DP4) but ...
de Leon Erich E - - 2012
Confocal microscopy rejects out-of-focus light from the object by scanning a pinhole through the image and reconstructing the image point by point. Volume holographic imaging systems with bright-field illumination have been proposed as an alternative to conventional confocal-type microscopes that does not require scanning of a pinhole or a slit. ...
Tang Guangwen - - 2012
Dietary β-carotene is the most important precursor of vitamin A. However, the determination of the efficiency of in vivo conversion of β-carotene to vitamin A requires sensitive and safe techniques. It presents the following challenges: 1) circulating β-carotene concentration cannot be altered by eating a meal containing ≤6 mg β-carotene; ...
Zegdi Rachid R Université René Descartes, Paris, France. - - 2013
The diagnostic accuracy of multiplane bi-dimensional transoesophageal echocardiography (TEE) in detecting aortic valve bicuspidy is good, but is less reliable when the leaflets are moderately or severely calcified. We hypothesized that systolic colour Doppler analysis might improve the accuracy of diagnosing aortic bicuspidy by TEE in patients with severe symptomatic ...
Zhao Guo-Yang - - 2012
Bone metabolism has a close relationship with iron homeostasis. To examine the effects of iron excess and iron deficiency on the biological activities of osteoblast in vitro, human osteoblast cells (hFOB1.19) were incubated in a medium supplemented with 0-200 μmol/L ferric ammonium citrate and 0-20 μmol/L deferoxamine. The intracellular iron was measured ...
Eitel Ingo I Department of Internal Medicine-Cardiology, University of Leipzig-Heart Center, Leipzig, Germany. - - 2012
Hyperglycemia on admission is associated with increased mortality rates in patients with ST-elevation myocardial infarction (STEMI). However, data regarding the relationship between hyperglycemia and myocardial damage in STEMI are scarce. The aim of this study was to determine the relationship of diabetes mellitus status and hyperglycemia on myocardial damage assessed ...
Lu Yi-Qun - - 2012
This study aims to explore the effect of advanced glycosylation end products (AGEs) on proliferation of human bone marrow mesenchymal stem cells in vitro and the underlying mechanism. Bone marrow cell proliferation was determined by WST-8 assay using Cell Counting Kit-8 under the intervention of AGEs. In addition, the content ...
Wei Meiying - - 2012
A bis-bisurea receptor () based on the R,R-cyclohexane-1,2-diamino scaffold forms an uncommon 2 : 2 complex () with the monohydrogen phosphate ion (HPO(4)(2-)) and a 1 : 1 complex () with the sulfate ion (SO(4)(2-)). Solution binding properties of the two anions were studied by (1)H NMR, UV-vis, and circular dichroism (CD) methods.
Torzilli Guido G Department of Surgery, Hepatobiliary Surgery Unit, Humanitas Cancer Center, Istituto Clinico Humanitas, IRCCS, University of Milan, Milan, Italy. - - 2013
Anatomical resection is the gold standard for liver resection in patients with hepatocellular carcinoma (HCC). Bimanual hepatic vessel compression has been already described, although segmental and subsegmental resection of segment 8 (S8) remain challenging by this technique. We demonstrate how to obtain a S8 demarcation by means of ultrasound-guided vessel ...
Monteleon Christine L - - 2012
Epithelial cysts comprise the structural units of the glandular epithelium. Although glandular inversion in epithelial tumors is thought to be a potential mechanism for the establishment of metastatic disease, little is known about the morphogenic cues and signaling pathways that govern glandular polarity and organization. Using organotypic cultures of Madin-Darby ...
Yu Dayu - - 2012
A putative indigoidine biosynthetic gene cluster was located in the genome of Streptomyces chromofuscus ATCC 49982. The silent 9.4-kb gene cluster consists of five open reading frames, named orf1, Sc-indC, Sc-indA, Sc-indB, and orf2, respectively. Sc-IndC was functionally characterized as an indigoidine synthase through heterologous expression of the enzyme in ...
Fernandes Rita Lencastre - - 2012
Despite traditionally regarded as identical, cells in a microbial cultivation present a distribution of phenotypic traits, forming a heterogeneous cell population. Moreover, the degree of heterogeneity is notably enhanced by changes in micro-environmental conditions. A major development in experimental single-cell studies has taken place in the last decades. It has ...
Höffner K - - 2012
Dynamic flux balance analysis (DFBA) provides a platform for detailed design, control and optimization of biochemical process technologies. It is a promising modeling framework that combines genome-scale metabolic network analysis with dynamic simulation of the extracellular environment. Dynamic flux balance analysis assumes that the intracellular species concentrations are in equilibrium ...
Zhang Jing - - 2012
SUMMARY AT A GLANCE: This study showed that underdiagnosis and undertreatment of COPD remains substantial in lung cancer patients. Documentation of smoking history or respiratory symptoms promotes disease diagnosis. Education of COPD knowledge among patients and doctors and improvement of disease management are urgently required in this special population. ABSTRACT: ...
Stanilov Noyko S - - 2012
The main regulator of anti-tumor immune response is the activity of monocytes, suggesting that the produced cytokines may have a prognostic role. This study investigates gene expression of interleukin (IL)-12-related cytokine and IL-10 in stimulated monocytes from colorectal cancer (CRC) patients. Relative quantification of IL-12A, IL-12B, IL-23A and IL-10 mRNA ...
Sonneville Romain - - 2012
OBJECTIVES: Cerebral toxoplasmosis remains a common neurologic complication in patients with AIDS. In this study, we aimed to characterize the prognosis of patients with HIV infection with severe forms of cerebral toxoplasmosis and to investigate the effects of adjunctive steroids on outcomes. METHODS: We carried out a retrospective cohort study ...
Goldstein Ido - - 2012
Cytochrome P450 enzymes (P450) are abundantly expressed in the human liver where they hydroxylate organic substrates. In a microarray screen performed in human liver cells, we found a group of eleven P450 genes whose expression was induced by p53 (CYP3A4, CYP3A43, CYP3A5, CYP3A7, CYP4F2, CYP4F3, CYP4F11, CYP4F12, CYP19A1, CYP21A2 and ...
Wang Yinan - - 2012
To know the involvement of glycosaminoglycans (GAGs) in the metastasis of mouse FBJ osteosarcoma cells, N ( α )-lauroyl-O-(β-D-xylopyranosyl)-L-serinamide (Xyl-Ser-C12), which initiates elongation of GAG chains using the glycan biosynthesis system in cells, was administered to FBJ cells with different metastatic capacities. Production of glycosylated products derived from Xyl-Ser-C12, especially ...
Philippot Remi R Department of Orthopaedic Surgery, University Hospital Center of Saint Etienne, Saint Étienne Cedex 2 42055, France. - - 2013
The dual-mobility concept was proposed as an alternative to prevent postoperative dislocation events. However, intraprosthetic dislocation (IPD) is a troublesome and specific complication induced by the loss of the polyethylene retentive rim and escape of the femoral head from the polyethylene liner. The factors associated with IPD are unknown as ...
Obeidat Basil R - - 2012
To assess the immuno-histochemical expression of various markers in, endometrial biopsies of patients with endometrial cancer, and to correlate their expression with the final pathologic findings. Sixty-two patients with primary endometrial cancer who underwent surgical treatment were included in this study. Immuno-histochemical expression of estrogen receptor (ER), progesterone receptor (PR), ...
Paletta Joseph T - - 2012
A series of sterically shielded pyrrolidine nitroxides were synthesized, and their reduction by ascorbate (vitamin C) indicate that nitroxide 3, a tetraethyl derivative of 3-carboxy-PROXYL, is reduced at the slowest rate among known nitroxides, i.e., at a 60-fold slower rate than that for 3-carboxy-PROXYL.
Gómez Eduardo J - - 2012
The politics of government response to health epidemics is a new area of scholarly research. Nevertheless, to date scholars have not considered how social science theory can be used and interdependently linked to provide a more thorough discussion of civil societal and national government response to different types of health ...
Bonderman D - - 2012
Precapillary pulmonary hypertension (PH) is diagnosed when mean pulmonary arterial pressure (mPAP) equals or exceeds 25 mmHg and the pulmonary capillary wedge pressure (PCWP) is equal or lower than 15 mmHg. Because both parameters can only be derived from invasive hemodynamic assessment, right heart catheter (RHC) is still a gold ...
Bierbaum Stefanie S Department of Training and Movement Sciences, Humboldt-University Berlin, Philippstr. 13, Haus 11, 10115, Berlin, - - 2013
Unexpected changes during gait challenge elderly individuals to a greater degree than young adults. However, the adaptive potential of elderly seems to be retained, and therefore, the training of the mechanisms of dynamic stability as well as muscle strength training may improve the dynamic stability after unexpected perturbations. Thirty-eight subjects ...
White Jim F JF Membrane Protein Structure Function Unit, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Department of Health and Human Services, Rockville, Maryland 20852, - - 2012
Neurotensin (NTS) is a 13-amino-acid peptide that functions as both a neurotransmitter and a hormone through the activation of the neurotensin receptor NTSR1, a G-protein-coupled receptor (GPCR). In the brain, NTS modulates the activity of dopaminergic systems, opioid-independent analgesia, and the inhibition of food intake; in the gut, NTS regulates ...
Gaidhu Mandeep P MP Muscle Health Research Center–School of Kinesiology and Health Science, York University, Toronto, Ontario, - - 2012
This study investigated the effects of chronic in vivo AMP-kinase activation with 5-aminoimidazole-4-carboxamide-1-β-d-ribofuranoside (AICAR) on lipolysis in subcutaneous inguinal, epididymal, and retroperitoneal fat pads. Male Wistar rats received daily single intraperitoneal injections of either saline or AICAR (0.7 g/kg body wt) for a period of 8 wk. The fat pads ...
Chin Brian L - - 2012
The connection between genotype and phenotype was assessed by determining the adhesion phenotype for the same mutation in two closely related yeast strains, S288c and Sigma, using two identical deletion libraries. Previous studies, all in Sigma, had shown that the adhesion phenotype was controlled by the filamentation mitogen-activated kinase (fMAPK) ...
Wang Guoxiang - - 2012
Five novel antimicrobial peptides (temporin-LK1, rugosin-LK1, rugosin-LK2, gaegurin-LK1, and gaegurin-LK2) are purified and characterized from Kuhl's wart frog skin secretions, Limnonectes kuhlii. They share obvious similarity to temporin, rugosin, and gaegurin antimicrobial peptide family, respectively. Their amino acid sequences were determined by Edman degradation and mass spectrometry, and further confirmed ...
Long Hélène - - 2012
New proposals for the diagnosis of gestational diabetes (GDM), promulgated by the International Association of Diabetes and Pregnancy Study Groups (IADPSG), will substantially increase the number of women diagnosed with GDM. This will have an enormous impact on healthcare resources, diverting attention away from genuinely high risk diabetic pregnancies. Randomized ...
Tsang Raymond S W - - 2012
This study examined serogroup B meningococci (MenB) from invasive meningococcal disease (IMD) cases in the provinces of Québec and Ontario in the last decade by multilocus sequence typing (MLST) to determine their sequence types (STs) and clonal complexes (CCs). Forty isolates from individual MenB IMD cases were found to belong ...
Zhu Shugao - - 2012
We report in this paper an interesting sequential reaction involving sequential Sonogashira coupling, propargyl-allenyl isomerization, [4 + 2] cycloaddition and aromatization reaction, which provides a facile method for the synthesis of a variety of polycyclic isoindoline derivatives from easily accessible starting materials.
Allario Thierry - - 2012
Whole-genome duplication, or polyploidy, is common in many plant species and often leads to better adaptation to adverse environmental condition. However, little is known about the physiological and molecular determinants underlying adaptation. We examined the drought tolerance in diploid (2x) and autotetraploid (4x) clones of Rangpur lime (Citrus limonia) rootstocks ...
< 7 8 9 10 11 12 13 14 15 16 17 >