Search Results
Results 501 - 550 of 5598
< 6 7 8 9 10 11 12 13 14 15 16 >
Kim Seok-Jo - - 2012
TGF-β-induced epithelial-mesenchymal transition (EMT) induces the proliferation and migration of the human lens epithelial (HLE) cells. Ganglioside GM3, a simple sialic acid-containing glycosphingolipids on mammalian cell membranes, regulates various pathological phenomena such as insulin resistance and tumor progression. However, the relation between ganglioside GM3 and TGF-β-induced EMT in the HLE ...
Yingguang Zhang - - 2012
Abstract Toxoplasma gondii is an important protozoan parasite that can infect virtually all warm-blooded animals, including humans; oocysts in the environment are an important infection source. Microtus fortis can be used as a sentinel reflecting the distribution of T. gondii oocysts in the environment indirectly. In the present study, we ...
Fortier Marie-Ève - - 2012
Exposure to stressors results in a spectrum of autonomic, endocrine, and behavioral responses. A key pathway in this response to stress is the hypothalamic-pituitary-adrenal (HPA) axis, which results in a transient increase in circulating cortisol, which exerts its effects through the two related ligand-activated transcription factors: the glucocorticoid receptor (GR) ...
Jin Yue - - 2012
A fast, simple and quantitative approach was established for monitoring autophagy in HeLa cells by directly detecting the conversion of green fluorescent protein (GFP) labelled autophagy markers, GFP-LC3-I to GFP-LC3-II, in crude cellular extract using capillary electrophoresis (CE) with laser-induced fluorescence (LIF). Compared with the traditional methods, this proposed method ...
Liang Jingjing - - 2012
The cellular prion protein (PrP (C) ) is subjected to various processing under physiological and pathological conditions, of which the α-cleavage within the central hydrophobic domain not only disrupts a region critical for both PrP toxicity and PrP (C) to PrP (Sc) conversion but also produces the N1 fragment that ...
Tuzcu E Murat - - 2012
The first mechanical heart valve prosthesis designed by Dr Charles Hufnagel was implanted to the descending aorta of a 30 year old woman with severe aortic regurgitation in 1952(1). Eight years after the initial succesful prosthetic valve implantation, Dr Harken sutured a prosthetic valve (Starr Edwards Valve) to the aortic ...
Gauthier Baptiste - - 2012
Both our environment and our behavior contain many spatiotemporal regularities. Preferential and differential tuning of neural populations to these regularities can be demonstrated by assessing rate dependence of neural responses evoked during continuous periodic stimulation. Here, we used functional magnetic resonance imaging to measure regional variations of temporal sensitivity along ...
Ding Shi-Ling - - 2012
This work aimed to investigate the effectiveness of ultraviolet (UV) radiation on the degradation of the antimicrobial triclocarban (TCC). We investigated the effects of several operational parameters, including solution pH, initial TCC concentration, photocatalyst TiO(2) loading, presence of natural organic matter, and most common anions in surface waters (e.g., bicarbonate, ...
Liu Yong - - 2012
The open reading frame 7a of the Bombyx mori nucleopolyhedrovirus (BmNPV orf7a, Bm7a) encodes a predicted polypeptide consisting of 53 amino acid residues. While this polypeptide's homologues were found in certain baculoviruses, its function has not yet been studied. A protein structural assay revealed that the polypeptide expressed from this ...
Helal Olfa - - 2012
The present study was aimed to investigate the effect of 12 weeks of extra-virgin olive oil (EVOO) consumption on the capacity of HDL to promote cholesterol efflux (CE) and to determine which CE pathways are modulated by EVOO consumption. Whole HDL and HDL2/HDL3 subclasses were isolated from the plasma of ...
Shao Yuan-Jun - - 2012
The first complete mitochondrial genome (mitogenome) of Tachinidae Exorista sorbillans (Diptera) is sequenced by PCR-based approach. The circular mitogenome is 14,960 bp long and has the representative mitochondrial gene (mt gene) organization and order of Diptera. All protein-coding sequences are initiated with ATN codon; however, the only exception is Cox I ...
Clayton Emma L - - 2012
The four mammalian phosphatidylinositol 4-kinases, together with the PI(4,5)P(2) depleting 5-phosphatases of the oculocerebrorenal syndrome of Lowe and synaptojanin families, modulate neuronal pools of PI4P lipid and regulate intracellular membrane trafficking in the endocytic and secretory pathways. Dysfunctions in these enzymes have been associated with a broad spectrum of disorders ...
Hayashi Nobuyuki - - 2012
To recognize α-amino acids with highly polar side chains in water, poorly water soluble scandium complexes with both Lewis acidic and basic portions were synthesized as artificial receptors. A suspension of some of these receptor molecules in an α-amino acid solution could remove acidic and basic α-amino acids from the ...
Göransson Erik - - 2012
In the context of long-range electron transfer for solar energy conversion, we present the synthesis, photophysical, and computational characterization of two new zinc(II) phthalocyanine oligophenylene-ethynylene based donor-bride-acceptor dyads: ZnPc-OPE-AuP(+) and ZnPc-OPE-C(60). A gold(III) porphyrin and a fullerene has been used as electron accepting moieties, and the results have been compared ...
Polat Zubeyda Akin - - 2012
Acanthamoeba keratitis (AK) is a potentially devastating and sight-threatening infection of the cornea caused by the ubiquitous free-living amoebae, Acanthamoeba species. Its eradication is difficult because the amoebas encyst, making it highly resistant to anti-amoebic drugs. Acriflavine neutral (ACF) has been used for treatment of microbial infections for humans and ...
Blendon Robert J - - 2012
The outcome of the 2012 election will have far-reaching ramifications for the future of U.S. health care. Rarely in a national election have the two major candidates' views about health care been so diametrically opposed. The views of President Barack Obama and Republican presidential nominee Mitt Romney differ on whether ...
Xiong Yule - - 2012
We use the LOCal oxidation of silicon (LOCOS) method as a fabrication technique to define submicrometer photonic waveguides. We attempted fabricating the wire waveguides with two different masking processes, one with a stack of pad oxide and silicon nitride layers, and the other with a single silicon nitride layer. The ...
Morris James A - - 2012
MOTIVATION: The existence of families with many individuals affected by the same complex disease has long suggested the possibility of rare alleles of high penetrance. In contrast to Mendelian diseases, however, linkage studies have identified very few reproducibly linked loci in diseases like diabetes and autism. Genome-wide association studies have ...
Nakajima Kentaro - - 2012
A rectoseminal vesicle fistula is a rare complication after a low anterior resection for rectal cancer, usually developing in the outpatient postoperative period with pneumaturia, fever, scrotal swelling or testicular pain. A diagnostic water-soluble contrast enema, cystography and computed tomography reveal a tract from the rectum to the seminal vesicle. ...
Antos Joseph - - 2012
In the wake of the Supreme Court decision, states should not rush to expand eligibility for Medicaid. They cannot be certain that the federal support promised in the Patient Protection and Affordable Care Act will remain available, and a better deal might be possible after the election. Adding millions more ...
Ito Shuichi - - 2012
BACKGROUND: Rituximab (RTX) is a promising option for treating childhood-onset steroid-dependent (SDNS), frequently relapsing (FRNS), and steroid-resistant (SRNS) nephrotic syndrome. METHODS: We retrospectively surveyed RTX treatment for these conditions to evaluate its indications, efficacy and adverse events. Questionnaires were sent to 141 hospitals in Japan. RESULTS: Seventy-four patients (52 SDNS; ...
Anckaert Ellen - - 2012
BACKROUNDFollicle culture and oocyte in vitro maturation (IVM) are emerging assisted reproductive technologies with potentially important future applications in the fertility clinic. There is concern that these technologies might interfere at the epigenetic level and, in particular, with genomic imprinting. The timely acquisition of correct imprinting patterns in oocytes and ...
Guerron Alfredo D - - 2012
BACKGROUND: Findings have shown laparoscopic liver resection (LLR) to be feasible and safe, but the data in the literature regarding oncologic outcomes are scant. This study aimed to compare the perioperative and short-term oncologic outcomes between LLR and open resection of colorectal liver metastasis (CLM). METHODS: Between January 2006 and ...
Trost Barry M - - 2012
Here it goes again: A tandem catalytic process that effects sequential Pd(0) -catalyzed allylic alkylations through leaving group ionization and Pd(II) -catalyzed allylic alkylations by CH activation is reported. By employing an oxidative trigger to convert the catalytic species from Pd(0) to Pd(II) , both transformations can be conducted in ...
Liu Xiaonao - - 2012
We describe an ink-jet printing assisted cooperative-assembly method for high-throughput generation of catalyst libraries (multi-component mesoporous metal oxides) at a rate of 1,000,000-formulations/hour with up to eight-component compositions. The compositions and mesostructures of the libraries can be well controlled and continuously varied. Fast identification of an inexpensive and efficient quaternary ...
Berhouma Moncef - - 2012
BACKGROUND: Since the introduction of the endoscopic endonasal approaches in the field of skull base surgery during the last two decades, several variants of the sella turcica endoscopic surgery have been described. The aim of this study is to provide a stepwise description of one of these variants in a ...
Heußner P - - 2012
The relationships between the psyche and cancer are manifold. Psycho-oncology focuses on the psychological adjustment to life-threatening illnesses. Crises are not unusual in health care, but the perception of cancer is totally different because the diagnosis of cancer often results in an irrational shock reaction in all parties involved. A ...
Krasovsky Tal - - 2012
Falls during walking are a major cause of injury in post-stroke individuals, and walking faster may further decrease gait stability. We compared gait stability between high-functioning post-stroke individuals and controls at matched speeds. We also evaluated the effect of a speed increase on gait stability in post-stroke individuals. Ten stroke ...
Trotman Carroll-Ann E - - 2012
Objectives :  (1) To collect three-dimensional, dynamic facial images from two groups of infants: one group born with cleft lip and palate slated to have a primary lip repair and a second, age-matched, noncleft control group. (2) To develop analyses to determine differences in facial movement between infants with cleft ...
Nguyen Khiem Van - - 2012
Present-day organisms are under constant environmental stress that damages bases in DNA, leading to mutations. Without DNA repair processes to correct these errors, such damage would be catastrophic. Organisms in all kingdoms have repair processes ranging from direct reversal to base excision and nucleotide excision repair, and the recently characterized ...
Tofighi Sara - - 2012
In this paper we study the optical bistability in a double coupler fiber ring resonator which consists of an erbium doped fiber amplifier (EDFA) in half part of the fiber ring and a quantum dot doped fiber (QDF) saturable absorber in the other half. The bistability is provided by the ...
Kreis Julia - - 2012
In the United States and internationally, the trend for public engagement in health policy and practice is increasing, particularly regarding health technology assessment (HTA), which informs often controversial coverage decisions. However, there is no consensus about which members of the public should be involved in which processes or what the ...
Jain Richa - - 2012
Superior Vena Cava Syndrome (SVCS) refers to signs and symptoms caused by obstruction of the superior vena cava. Superior mediastinal syndrome (SMS) is the term used when SVCS coexists with obstruction of trachea. In children, a mediastinal pathology causing SVCS generally results in SMS as well, due to the limited ...
Huang Hui - - 2012
In this paper, one-dimensional (1D) mesoporous single-crystalline Co3O4 nanobelts are synthesized by a facile hydrothermal method followed by calcination treatment. The as-prepared nanobelts have unique mesoporous structures, which are constructed by many interconnected nanocrystals with sizes of about 20-30 nm. And typical size of the nanobelts is in the range ...
Ogouyèmi-Hounto A - - 2012
The aim of the study was to determine the accuracy of a rapid diagnostic test (SD Bioline Malaria Ag P.f/ Pan®) and fluorescent microscopy (CyScope®) in confirming presumptive malaria diagnosis in Cotonou. Thick blood smear was used as the reference technique for comparison. Testing was conducted on persons between the ...
Monico Letizia - - 2012
Previous investigations about the darkening of chrome yellow pigments revealed that this form of alteration is attributable to a reduction of the original Cr(VI) to Cr(III) and that the presence of sulfur-containing compounds, most often sulfates, plays a key role during this process. We recently demonstrated that different crystal forms ...
Fijlstra Margot - - 2012
It is unknown what feeding strategy to use during chemotherapy-induced gastrointestinal mucositis, which causes weight loss and possibly malabsorption. To study the absorptive capacity of amino acids during mucositis, we determined the plasma availability of enterally administered amino acids (AA), their utilization for protein synthesis, and the preferential side of ...
Gao Hongli - - 2012
Yerba Mate tea (Mate) is believed to be a natural source of cardioprotective lipid-lowering and antioxidant compounds. In this study, the antihyperlipidemic and antioxidant effects of Mate tea in a rat hyperlipidemia model were investigated. Male Sprague-Dawley rats were divided randomly into five groups and fed varying diets: standard diet, ...
Leja Chris - - 2012
Lasers have been proposed for various applications involving dental implants, including uncovering implants and treating peri-implantitis. However, the effect of laser irradiation on the implant surface temperature is only partially known. The aim of this pilot study was to determine the effect of irradiation with diode, carbon dioxide, and Er:YAG ...
Kim Tark - - 2012
R-CHOP chemotherapy composed of rituximab, cyclophosphamide, adriamycin, vincristine, and prednisolone which might increase the risk of Pneumocystis pneumonia in patients with non-Hodgkin lymphoma. We estimated the point prevalence of Pneumocystis pneumonia in non-Hodgkin lymphoma patients according to the number of R-CHOP cycles and investigated whether cytoreduction by chemotherapy is associated ...
Menger-Krug Eve Katrin - - 2012
Integrating microalgae systems (MAS) at municipal wastewater treatment plants (WWTPs) to produce of bio energy offers many potential synergies. Improved energy balances provide a strong incentive for WWTPs to integrate MAS, but it is crucial that WWTPs maintain their barrier function to protect water resources. We perform a prospective analysis ...
de Leon Erich E - - 2012
Confocal microscopy rejects out-of-focus light from the object by scanning a pinhole through the image and reconstructing the image point by point. Volume holographic imaging systems with bright-field illumination have been proposed as an alternative to conventional confocal-type microscopes that does not require scanning of a pinhole or a slit. ...
Tang Guangwen - - 2012
Dietary β-carotene is the most important precursor of vitamin A. However, the determination of the efficiency of in vivo conversion of β-carotene to vitamin A requires sensitive and safe techniques. It presents the following challenges: 1) circulating β-carotene concentration cannot be altered by eating a meal containing ≤6 mg β-carotene; ...
Zhao Guo-Yang - - 2012
Bone metabolism has a close relationship with iron homeostasis. To examine the effects of iron excess and iron deficiency on the biological activities of osteoblast in vitro, human osteoblast cells (hFOB1.19) were incubated in a medium supplemented with 0-200 μmol/L ferric ammonium citrate and 0-20 μmol/L deferoxamine. The intracellular iron was measured ...
Lu Yi-Qun - - 2012
This study aims to explore the effect of advanced glycosylation end products (AGEs) on proliferation of human bone marrow mesenchymal stem cells in vitro and the underlying mechanism. Bone marrow cell proliferation was determined by WST-8 assay using Cell Counting Kit-8 under the intervention of AGEs. In addition, the content ...
Wei Meiying - - 2012
A bis-bisurea receptor () based on the R,R-cyclohexane-1,2-diamino scaffold forms an uncommon 2 : 2 complex () with the monohydrogen phosphate ion (HPO(4)(2-)) and a 1 : 1 complex () with the sulfate ion (SO(4)(2-)). Solution binding properties of the two anions were studied by (1)H NMR, UV-vis, and circular dichroism (CD) methods.
Yu Dayu - - 2012
A putative indigoidine biosynthetic gene cluster was located in the genome of Streptomyces chromofuscus ATCC 49982. The silent 9.4-kb gene cluster consists of five open reading frames, named orf1, Sc-indC, Sc-indA, Sc-indB, and orf2, respectively. Sc-IndC was functionally characterized as an indigoidine synthase through heterologous expression of the enzyme in ...
Fernandes Rita Lencastre - - 2012
Despite traditionally regarded as identical, cells in a microbial cultivation present a distribution of phenotypic traits, forming a heterogeneous cell population. Moreover, the degree of heterogeneity is notably enhanced by changes in micro-environmental conditions. A major development in experimental single-cell studies has taken place in the last decades. It has ...
Höffner K - - 2012
Dynamic flux balance analysis (DFBA) provides a platform for detailed design, control and optimization of biochemical process technologies. It is a promising modeling framework that combines genome-scale metabolic network analysis with dynamic simulation of the extracellular environment. Dynamic flux balance analysis assumes that the intracellular species concentrations are in equilibrium ...
Zhang Jing - - 2012
SUMMARY AT A GLANCE: This study showed that underdiagnosis and undertreatment of COPD remains substantial in lung cancer patients. Documentation of smoking history or respiratory symptoms promotes disease diagnosis. Education of COPD knowledge among patients and doctors and improvement of disease management are urgently required in this special population. ABSTRACT: ...
< 6 7 8 9 10 11 12 13 14 15 16 >