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Results 251 - 300 of 3015
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Malinauskiene Laura - - 2012
Several disperse dyes (DDs) are still considered to be the most important allergens in textile dermatitis, but there are sparse data about their current use in textiles. The aim of this review was to evaluate published studies and reports on contact allergy to DDs published in PubMed during the last ...
Dubuisson C - - 2012
Background/Objective:Our objective was to investigate whether school lunch attendance was associated with overall eating habits and sedentary behaviour in a French sample of children and adolescents.Subjects/Methods:Data for the study were taken from the second French cross-sectional dietary survey (INCA2-2006-07). In total, 1413 school children aged 3-17 years old were classified ...
van Vught Anneke J A H - - 2012
The amino acid arginine is a well-known growth hormone (GH) stimulator and GH is an important modulator of linear growth. The aim of the present study was to investigate the effect of dietary arginine on growth velocity in children between 7 and 13 years of age. Data from the Copenhagen ...
Skovgaard Alf - - 2012
The myxozoan Tetracapsuloides bryosalmonae is the causative agent of proliferative kidney disease (PKD), a widespread and serious condition in salmonid fishes in Europe and North America. In Europe, PKD is primarily reported affecting farmed rainbow trout Oncorhynchus mykiss, but limited information exists on the occurrence and effects of T. bryosalmonae ...
Huang Sheng-You SY Department of Physics and Astronomy, University of Missouri, Columbia, Missouri 65211, - - 2013
Protein-RNA interactions play an important role in many biological processes. The ability to predict the molecular structures of protein-RNA complexes from docking would be valuable for understanding the underlying chemical mechanisms. We have developed a novel nonredundant benchmark dataset for protein-RNA docking and scoring. The diverse dataset of 72 targets ...
Stewart Merry - - 2012
AIM: To explore the influence of the haemodialysis regimen on African Americans' perceptions of sexuality. BACKGROUND: Sexuality is defined as the quality of humans as males or females. Sexuality concerns are commonly reported for individuals receiving haemodialysis; yet, sexuality-related research for this population has been limited to a focus on ...
Jang Seong Soon - - 2012
Abstract Purpose: The modification of radiation-induced lung injuries by melatonin was studied by measuring changes in oxidative stress, cytokine expression and histopathology in the lung tissue of mice following irradiation. Materials and methods: The thoraces of C57BL/6 mice were exposed to a single X-ray radiation dose of 12 Gy with ...
Cheng Bastian B Klinik und Poliklinik für Neurologie, Kopf- und Neurozentrum, Universitätsklinikum Hamburg-Eppendorf, Hamburg, Germany. - - 2013
In acute stroke magnetic resonance imaging, a 'mismatch' between visibility of an ischemic lesion on diffusion-weighted imaging (DWI) and missing corresponding parenchymal hyperintensities on fluid-attenuated inversion recovery (FLAIR) data sets was shown to identify patients with time from symptom onset ≤4.5 hours with high specificity. However, moderate sensitivity and suboptimal ...
Broderick Carolyn R CR Sydney Medical School, University of Sydney, Sydney, NSW, Australia. - - 2012
Vigorous physical activity is thought to increase risk of bleeds in children with hemophilia, but the magnitude of the risk is unknown. To quantify the transient increase in risk of bleeds associated with physical activity in children with hemophilia. A case-crossover study nested within a prospective cohort study was conducted ...
Aznar M N - - 2012
Bovine brucellosis is a zoonotic disease spread worldwide. The infection in cattle is predominantly caused by Brucella abortus and is usually detected in pregnant females through abortions. The disease is endemic in Argentina; however, infection in humans is underestimated and often not reported. The prevalence of bovine brucellosis in countries ...
Cavazzoni Emanuel - - 2012
Aim:  The effectiveness of Doppler guided transanal haemorrhoidal dearterialization (THD) was studied in arresting persistent haemorrhoidal bleeding in patients admitted as an emergency. Method:  Eleven patients with severe anal bleeding underwent emergency THD as definitive treatment for haemorrhoids. In the majority of patients antiplatelet or anticoagulant therapy was ongoing and ...
Uchiumi Takeshi - - 2012
Dubin-Johnson syndrome (DJS) is a recessive inherited disorder characterized by conjugated hyperbilirubinemia. It is caused by dysfunction of adenosine triphosphate-binding cassette, sub-family C, member 2 (ABCC2/MRP2) on the canalicular membrane of hepatocytes. We performed mutational analysis of the ABCC2/MRP2 gene in a Japanese female with DJS. Furthermore, we investigated the ...
Rivera Norma - - 2012
The compound VAM2-6 (1-methyl-7-nitro-4-(5-(piperidin-1-yl)pentyl)-3,4-dihydroquinoxalin-2(1H)-one) has previously been shown to have an in vitro efficacy of 100% at a concentration of 100 µg ml(-1) against Trichomonas vaginalis, a protozoon parasite that causes the sexually transmitted disease trichomoniasis. Because VAM2-6 is a quinoxaline derivative and given the lack of studies on the genotoxic activity ...
Melander Olle O Department of Clinical Sciences, Lund University, Malmö, Sweden. - - 2012
Neurotensin regulates both satiety and breast cancer growth in the experimental setting, but little is known about its role in the development of breast cancer or cardiometabolic disease in humans. To test if fasting plasma concentration of a stable 117-amino acid fragment from the neurotensin precursor hormone proneurotensin is associated ...
Evander Mikael - - 2012
This part of the Acoustofluidics tutorial series reviews applications in acoustic trapping of micron-sized particles and cells in microfluidic systems. Acoustic trapping enables non-invasive and non-contact immobilisation of cells and particles in microfluidic systems. Acoustic trapping has been used for reducing the time needed to create 3D cell clusters, enhance ...
Zhan Yihong - - 2012
The biomechanics of erythrocytes, determined by the membrane integrity and cytoskeletal structure, provides critical information on diseases such as diabetes mellitus, myocardial infarction, hypertension, and sickle cell anemia. Here we demonstrate a simple microfluidic tool for examining erythrocyte fragility based on characterizing osmotic lysis kinetics. Hydrodynamic focusing is used for ...
Tran Nga L - - 2012
Usual intake estimates describe long-term average intake of food and nutrients and food contaminants. The frequencies of fish and shellfish intake over a 30-day period from National Health and Examination Survey (NHANES 1999-2006) were combined with 24-h dietary recall data from NHANES 2003-2004 using a Monte Carlo procedure to estimate ...
Hutchinson L M - - 2012
BACKGROUND: Although staff attitudes towards individuals with intellectual disability (ID) whose behaviour challenges may be an important part of a positive support culture, very little research has focused on the development of training specifically designed to change staff attitudes. Positive contact is hypothesised to be an effective way to change ...
Zhang Yi - - 2012
The mechanism(s) by which hydrogen peroxide (H2O2) is photo-produced by humic substances (HS) and chromophoric dissolved organic matter (CDOM) was probed by examining the dependence of the initial H2O2 photo-production rate (RH2O2) and apparent H2O2 quantum yields on dioxygen concentration for both untreated and borohydride-reduced samples. Although borohydride reduction substantially ...
Vinther-Jensen Tua T Memory Disorders Research Group, Neurogenetics Clinic, Department of Neurology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, - - 2013
The spinocerebellar ataxias (SCA) are a genetically and clinically heterogeneous group of diseases, characterized by dominant inheritance, progressive cerebellar ataxia and diverse extracerebellar symptoms. A subgroup of the ataxias is caused by unstable CAG-repeat expansions in their respective genes leading to pathogenic expansions of polyglutamine stretches in the encoded proteins. ...
Allemani Claudia - - 2012
Few studies have addressed longer-term survival for breast cancer in European women. We have made predictions of ten-year survival for European women diagnosed with breast cancer in 2000-2002. Data for 114,312 adult women (15-99 years) diagnosed with a first primary malignant cancer of the breast during 2000-2002 were collected in ...
Chng J P L - - 2012
BACKGROUND: As adults with intellectual disability age, retirement options need to be explored. One option is to attend a mainstream community group for retirees. Support within these groups could come from group members who are trained to act as mentors for the older adults with intellectual disability. This research evaluated ...
Finsterer J - - 2012
Cerebral involvement in parasitoses is an important clinical manifestation of most of the human parasitoses. Parasites that have been described to affect the central nervous system (CNS), either as the dominant or as a collateral feature, include cestodes (Taenia solium (neurocysticerciasis), Echinococcus granulosus (cerebral cystic echinococcosis), E. multilocularis (cerebral alveolar ...
Szterk Arkadiusz - - 2012
A novel method to determine of azaarenes in refined and cold-pressed vegetable oils and animal fats is reported. The method may be used to determine eight most important acridine derivatives (benz[a]acridine, dibenz[a,i]acridine, benz[c]acridine, dibenz[a,j]acridine, 7,9-dimethylbenz[c]acridine, dibenz[a,h]acridine, dibenz[a,c]acridine, dibenz[c,h]acridine) at a high sensitivity (LOQ in the 2-25 ng kg(-1) range), high ...
Banks M D - - 2012
BACKGROUND/OBJECTIVES:This study estimates the economic outcomes of a nutrition intervention to at-risk patients compared with standard care in the prevention of pressure ulcer.SUBJECTS/METHODS:Statistical models were developed to predict 'cases of pressure ulcer avoided', 'number of bed days gained' and 'change to economic costs' in public hospitals in 2002-2003 in Queensland, ...
Pénichoux Juliette - - 2012
In the risk analysis of sequential events, the successive gap times are often correlated, e.g. as a result of an individual heterogeneity. Correlation is usually accounted for by using a shared gamma-frailty model, where the variance φ of the random individual effect quantifies the correlation between gap times. This method ...
Ambrosetti Patrick - - 2012
I thank Dr Biondo for his letter and am pleased to comment on his pertinent remarks. I agree with his statement that we are still ignorant of many areas of diverticular disease, but concerning the controversial debate about age, I would like to propose some arguments that could explain our ...
Lupo F N - - 2012
Objective: In cancer care, the burden of psycho-emotional elements involved on the patient-healthcare provider relationship cannot be ignored. The aim of this work is to have an impact on the level of burnout experienced by European Institute of Oncology (IEO) gynecologic oncology nurses (N = 14) and on quality of multidisciplinary team ...
Groeber Florian Kai - - 2012
A pivotal requirement for the generation of vascularized tissue equivalents is the development of culture systems that provide a physiological perfusion of the vasculature and tissue-specific culture conditions. Here, we present a bioreactor system that is suitable to culture vascularized tissue equivalents covered with culture media and at the air-medium ...
Li Qin - - 2012
One conceptual mechanism for the induction of associative long-term memory is that a synaptic tag, set by a weak event, can capture plasticity-related proteins from a nearby strong input, thus enabling associativity between the 2 (synaptic tagging and capture, STC). So far, STC has been observed for only a limited ...
Abe Sanae - - 2012
Abstract Purpose: To clarify the mechanism of prostaglandin (PG) analogue-dependent relaxation in ciliary arteries from wild-type (WT) and PG receptor-deficient mice. Methods: The intracellular-free calcium concentration ([Ca(2+)](i)) in isolated WT mouse ciliary arteries was measured by fluorescence photometry. Reduction of [Ca(2+)](i) leading to vascular relaxation by PG analogues latanoprost, isopropyl ...
Packnett Elizabeth R - - 2012
Since the start of Operation Iraqi Freedom and Operation Enduring Freedom, over 2 million U.S. military members were deployed to Iraq and Afghanistan. The estimated prevalence of posttraumatic stress disorder (PTSD) among soldiers and Marines returning from combat zones varies from 5%-20%; little is known about those individuals whose PTSD ...
Chen Yiping - - 2012
Molecularly imprinted film with diphenolic acid (DPA) as dummy template molecule has been grafted on the surface of Mn doped ZnS quantum dots (QDs) to develop a selective and sensitive sensor for rapid determination of Tetrabromobisphenol A (TBBPA) in water and soils. The obtained DPA-MIP-QDs sensor has distinguished selectivity and ...
Hovorka Roman R Metabolic Research Laboratories, Institute of Metabolic Science, Cambridge, United Kingdom. - - 2013
We investigated whether continuous glucose monitoring (CGM) levels can accurately assess glycemic control while directing closed-loop insulin delivery. Data were analyzed retrospectively from 33 subjects with type 1 diabetes who underwent closed-loop and conventional pump therapy on two separate nights. Glycemic control was evaluated by reference plasma glucose and contrasted ...
Shoshani Ofer - - 2012
Mesenchymal stromal cells (MSCs) are used extensively in clinical trials; however, the potential for malignant transformation of MSCs has been raised. We examined the genomic stability versus the tumor forming capacity of multiple mouse MSCs. Murine MSCs have been shown to be less stable and more prone to malignant transformation ...
Rachmawati Heni - - 2012
Curcumin, a naturally occuring polyphenolic phytoconstituent, is isolated from the rhizomes of Curcuma longa Linn. (Zingiberaceae). It is water insoluble under acidic or neutral conditions but dissolves in alkaline environment. In neutral or alkaline conditions, curcumin is highly unstable undergoing rapid hydrolytic degradation to feruloyl methane and ferulic acid. Thus, ...
Hidalgo-Tallón Javier - - 2012
Abstract Objectives: The objectives of this study were to evaluate the effectiveness and tolerability of ozone therapy by rectal insufflation as add-on therapy in fibromyalgia management. Design: Patients with fibromyalgia received 24 sessions of ozone therapy during a 12-week period. At each session, the administered dose of ozone was 8 mg ...
Saha S - - 2012
Apart from their role in cardiovascular homeostasis and immunomodulation, aldosterone and cortisol are also implicated in the pathogenesis of insulin resistance and type 2 diabetes mellitus (T2DM). Furthermore, glycoxidative modifications of lipoproteins are increasingly recognized as an etiological factor for increased cardiovascular morbidity and mortality in prediabetic individuals. The causative ...
Dong Haiqing - - 2012
A multi-component nanosystem based on graphene and comprising individual cyclodextrins at its surface is assembled, creating hybrid structures enabling new and important functionalities: optical imaging, drug storage, and cell targeting for medical diagnosis and treatment. These nanohybrids are part of a universal system of interchangeable units, capable of mutilple functionalities. ...
Namtvedt Silje K SK Department of Internal Medicine, Division of Medicine, Akershus University Hospital, Lorenskog, - - 2013
Obstructive sleep apnoea (OSA) and obesity are both associated with endothelial dysfunction, which precedes the development of atherosclerosis. As obesity is highly prevalent in OSA, we wanted to test the hypothesis that OSA is associated with endothelial dysfunction independently of obesity. Cross-sectional, population-based study. Norwegian university hospital. Seventy-one subjects (median ...
Theoduloz Cristina - - 2012
The stem bark of Tabebuia species and the rhizomes of Jatropha isabelii are used in Paraguayan traditional medicine to treat gastric lesions and as anti-inflammatory agents. The sesquiterpene cyperenoic acid obtained from J. isabelii has been shown to display a gastroprotective effect in animal models of induced gastric ulcers while ...
Bernardo Bianca C - - 2012
MicroRNAs are dysregulated in a setting of heart disease and have emerged as promising therapeutic targets. MicroRNA-34 family members (miR-34a, -34b, and -34c) are up-regulated in the heart in response to stress. In this study, we assessed whether inhibition of the miR-34 family using an s.c.-delivered seed-targeting 8-mer locked nucleic ...
Wu J - - 2012
Molecules show a much increased multiple ionization rate in a strong laser field as compared with atoms of similar ionization energy. A widely accepted model attributes this to the action of the joint fields of the adjacent ionic core and the laser on its neighbour inside the same molecule. The ...
Metsavaht Leonardo L Instituto Brasil de Tecnologias da Saúde, Rio de Janeiro, Brazil. - - 2012
Clinical measurement. To translate and culturally adapt the Lower Extremity Functional Scale (LEFS) into a Brazilian Portuguese version, and to test the construct and content validity and reliability of this version in patients with knee injuries. There is no Brazilian Portuguese version of an instrument to assess the function of ...
Hong Jong Soo - - 2012
Various methods of photodynamic therapy (PDT) for acne have been introduced. However, comparative studies among them are still needed. We performed this study to compare the effect of methyl aminolevulinate (MAL) PDT for acne between red light and intense pulsed light (IPL). Twenty patients were enrolled in this eight-week, prospective, ...
Berghoff A S - - 2012
The clinical course of breast cancer patients with brain metastases (BM) as only metastatic site (brain-only metastatic breast cancer (BO-MBC)) has been insufficiently explored. All breast cancer patients with BM treated at our institution between 1990 and 2011 were identified. For each patient, full information on follow-up and administered therapies ...
Chen Baoen - - 2012
The direct nucleic acid repair dioxygenase FTO is an enzyme that demethylates N6-methyladenosine (m6A) residues in mRNA in vitro and inside cells. FTO is the first RNA demethylase discovered that also serves a major regulatory function in mammals. Together with structure-based virtual screening and biochemical analyses, we report the first ...
Kidane Dawit - - 2012
Natural transformation is a programmed mechanism characterized by binding of free double-stranded (ds) DNA from the environment to the cell pole in rod-shaped bacteria. In Bacillus subtilis some competence proteins, which process the dsDNA and translocate single-stranded (ss) DNA into the cytosol, recruit a set of recombination proteins mainly to ...
Hutton Jonathon - - 2012
INTRODUCTION: This article describes how patients with metastatic spinal cord compression (MSCC) were treated from 2005 to 2011 at a single institution. A comparison is made with an international and standardized scoring system which would have predicted which patients would have a better outcome with neurosurgery in addition to radiotherapy ...
Sezer Rabia Gönül - - 2012
Abstract Background: This study investigated the association among breastfeeding, serum zinc levels, and nutritional status of children. Subjects and Methods: One hundred healthy infants were included in the study. Anthropometric measurements of the children were taken, and their plasma zinc levels were determined. The mothers were interviewed about the duration ...
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