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Janghorbani Mohsen - - 2012
Abstract Background: The aim of this study was to determine the ability of glycated hemoglobin (GHb) to predict metabolic syndrome in an Iranian population with normal glucose tolerance (NGT). Methods: A cross-sectional study of first-degree relatives (FDRs) of patients with type 2 diabetes was conducted from 2003 to 2005. A ...
Park Minsung - - 2012
Magnetic nanoparticles (MNPs) were covalently immobilized on the surface of Acetobacter xylinus and the location of the bacteria was controlled to manipulate bacterial bioactivation. The bacteria were positioned in the middle of an incubation tube by applying an external magnetic field, and the cellulose produced at the different metabolizing locations ...
Gatrell S K - - 2012
The primary pathway of lysine degradation in pigs presumably depends on the bifunctional protein α-aminoadipate δ-semialdehyde synthase (AASS), which contains lysine α-ketoglutarate reductase (LKR) and saccharopine dehydrogenase (SDH) activities. In liver, AASS is restricted to the mitochondrial matrix and lysine is presumptively transported through the plasma membrane by a cationic ...
Petersen Julien - - 2012
Organosilicon plasma polymer and silica-like layers are deposited at different temperatures in a dielectric barrier discharge at atmospheric pressure operating in the Townsend regime. Final properties of these two kinds of layers can be finely tuned by the plasma process conditions. In particular, influence of deposition temperature is investigated when ...
Chen Jun - - 2012
The endoplasmic reticulum (ER) is an interconnected network comprised of ribosome-studded sheets and smooth tubules. The ER plays crucial roles in the biosynthesis and transport of proteins and lipids, and in calcium (Ca(2+) ) regulation in compartmentalized eukaryotic cells including plant cells. To support its well-segregated functions, the shape of ...
Littlefield Benjamin T R - - 2012
Nanoporous materials have important industrial applications as molecular sieves, catalysts and in gas separation and storage. They are normally produced as moderately dense silicates (SiO(2)) and aluminosilicates making their specific capacities for the uptake and storage of gases, such as hydrogen, relatively low. Here we report the synthesis and characterization ...
Shui Jiang-Lan - - 2012
Using a microfocused synchrotron X-ray diffraction (μ-XRD) method, we systematically investigated the distributions of insoluble lithium precipitates, which formed through electrolyte decomposition, separately in all three regions (cathode, separator, and anode) of failed batteries with a spatial resolution of 20 μm. We found unexpectedly that there was a significantly higher concentration ...
Aung Kyaw - - 2012
Dynamin-related proteins (DRPs) are key components of the organelle division machineries, functioning as molecular scissors during the fission process. In Arabidopsis, DRP3A and DRP3B are shared by peroxisomal and mitochondrial division, whereas the structurally-distinct DRP5B (ARC5) protein is involved in the division of chloroplasts and peroxisomes. Here, we further investigated ...
Valizadeh H - - 2012
In the present study pharmacokinetics and bioequivalence of 2 brands of ciprofloxacin 500 mg were evaluated in 24 healthy male volunteers after a single dose oral administration in an open, randomized, 2-way crossover study.Blood samples were taken before and within 12 h after the administration of the drug. Plasma concentrations of ciprofloxacin ...
Wang Xu-Dong - - 2012
Living color: Fluorescent pH-sensitive nanoparticles 12 nm in diameter were prepared and incorporated into agarose gel in a Petri dish to image pH changes during bacterial growth and metabolism.
Das Suresh - - 2012
Star-shaped molecules consisting of a 1, 3, 4-oxadiazole core derivatized with alkoxy substituted phenyl ethynylenes, FD12 (dodecyl) and FD16 (hexadecyl) were synthesized. These molecules exhibited enantiotropic columnar mesophases over a wide temperature range, with the liquid crystalline phases exhibiting strong blue fluorescence. On cooling FD12 transformed into a transparent glass ...
Compare Angelo - - 2012
Background: Binge eating disorder (BED) is a complex and multifaceted eating disorder and the literature indicates that BED patients show greater difficulty identifying and making sense of emotional states, and that they have limited access to emotion regulation strategies. Findings show many links between mindfulness and emotional regulation however there ...
Race Margaret - - 2012
Abstract This paper reports recent efforts to gather experts from the humanities and social sciences along with astrobiologists to consider the cultural, societal, and psychological implications of astrobiology research and exploration. We began by convening a workshop to draft a research roadmap on astrobiology's societal implications and later formed a ...
Venugopal Ram Rao - - 2012
A 36-year old woman presented with a 5-year history of progressive dysphagia. The barium swallow of the oesophagus revealed an oblique extrinsic defect consistent with an aberrant right subclavian artery. A computed tomography angiogram confirmed the diagnosis. Surgical correction is indicated for dysphagia lusoria in association with an aberrant right ...
Sejersen H - - 2012
We have investigated the liver response in young pigs to a high-fat diet (containing 25% animal fat) and diet restriction (equivalent to 60% of maintenance) using differential proteome analysis. The objective was to investigate whether young pigs can be used to model the liver response in adolescents to a high-fat ...
Mackay J - - 2012
Objectives of this study were: (i) to compare fatty acid composition of subcutaneous adipose tissue of entire boars, barrows, and male pigs vaccinated against boar taint with a vaccine containing a GnRH analogue-protein conjugate (Improvac, Pfizer Animal Health), and (ii) to investigate the association between fatty acid composition and protein ...
Ashe Leah M - - 2012
Public health nutrition sits at the nexus of a global crisis in food, environmental and health systems that has generated - along with numerous other problems - an urgent and changing problem of food insecurity. The 'new' food insecurity, however, is different from the old: it is bimodal, encompassing issues ...
Schmidt Markus A - - 2012
Optical nanosensors based on plasmonic nanoparticles have great potential for chemical and biological sensing applications, but their spectral detection resolution is severely constrained by their broad resonance linewidth, and their spatial sensing depth is limited to several tens of nanometres. Here we demonstrate that coupling a strong dipolar plasmonic resonance ...
Pavord Ian D - - 2012
The identification of phenotypes of asthma has a long history, but previous classifications have not identified clinically important differences in pathology, natural history, or treatment response. Progress has accelerated recently, fueled by the development of new techniques to assess airway disease, particularly noninvasive techniques to assess airway inflammation. This article ...
Tsatalas Themistoklis - - 2012
Abstract This study investigated the effects of knee localised muscle damage on running kinematics at varying speeds. Nineteen young women (23.2 ± 2.8 years; 164 ± 8 cm; 53.6 ± 5.4 kg), performed a maximal eccentric muscle damage protocol (5 × 15) of the knee extensors and flexors of both legs at 60 rad · s(-1). Lower body kinematics was assessed ...
Merstorf Céline - - 2012
Being able to differentiate local fluctuations from global folding/unfolding dynamics of a protein is of major interest for better understanding structure/function determinants. The maltose binding protein (MBP), a protein that belongs to the maltose transport system, has a structure composed of two globular domains separated by a rigid-body "hinge-bending". Here, ...
Merrill Tl - - 2012
Therapeutic hypothermia can reduce both ischemic and reperfusion injury arising after strokes and heart attacks. New localized organ cooling systems offer a way to reduce tissue damage more effectively with fewer side effects. To assess initial blood safety of our new organ cooling system, the CoolGuide Cooling System (CCS), we ...
Jang Kerry L - - 2012
The University of British Columbia (UBC) Twin Project is a registry of approximately 2,000 pairs of reared-together twins recruited across the major Canadian provinces. The focus of the project is an investigation of the behavioral genetics of personality and its disorders, and their relationship to other forms of mental illness. ...
Reuter R R - - 2012
Stocker cattle production practices may affect subsequent performance of cattle in economically meaningful ways. Literature was reviewed to summarize possible carryover effects of stocker cattle management on finishing performance and carcass traits. The most consistent effects of stocker phase practices on finishing-phase and carcass performance of cattle appear to be ...
Ndrepepa Gjin - - 2012
BACKGROUND: THE OPTIMAL ANTITHROMBOTIC THERAPY FOR PATIENTS WITH NONST-SEGMENT ELEVATION MYOCARDIAL INFARCTION UNDERGOING PERCUTANEOUS CORONARY INTERVENTION IS NOT WELL DEFINED. WE INVESTIGATED THE EFFICACY AND SAFETY OF BIVALIRUDIN VERSUS HEPARIN PLUS A GLYCOPROTEIN IIB/IIIA INHIBITOR (GPI) IN PATIENTS WITH NONST-SEGMENT ELEVATION MYOCARDIAL INFARCTION UNDERGOING PERCUTANEOUS CORONARY INTERVENTION AFTER CLOPIDOGREL PRETREATMENT.METHODS ...
Carter Frances A - - 2012
Objective:To evaluate the suitability and acceptability of computerised cognitive behaviour therapy (CCBT).Method:Participants were patients who had been referred to a secondary care service in the usual manner, and then offered participation in a randomised controlled trial comparing the efficacy of CCBT with a control condition (waitlist) for patients with a ...
Rodriguez-Mateos Ana - - 2012
Growing evidence suggests that intake of flavonoid-containing foods may exert cardiovascular benefits in human subjects. We have investigated the effects of a 10-week blueberry (BB) supplementation on blood pressure (BP) and vascular reactivity in rats fed a high-fat/high-cholesterol diet, known to induce endothelial dysfunction. Rats were randomly assigned to follow ...
Reginskaya Irina - - 2012
The mechanism which leads to a dielectric barrier electrospray (DB-ES) was investigated by measurements of the electrical current. It comprises several components, namely the displacement current, currents which are initiated by electromagnetic transmission, an ion current inside the capillary which is responsible for the built-up of the potential at the ...
Lee Young Bok - - 2012
Background  The aim of this study was to evaluate whether Fas (CD95) and Fas ligand (FasL) immunoreactivity in cutaneous squamous cell carcinoma (SCC) are correlated with grade of tumor differentiation. Methods  A total of 31 cutaneous SCC specimens excised during 1997-2004 were collected from the four branch hospitals of the ...
Laurberg Jens R - - 2012
What's known on the subject? and What does the study add? Several studies have shown that defects in DNA-damage response are associated with good survival after chemotherapy and radiotherapy. Furthermore, loss of cell cycle regulators may be prognostic indicators of poor survival after cystectomy. However, the potential clinical impact of ...
Marshall Lewis A - - 2012
Preparation of raw, untreated biological samples remains a major challenge in microfluidics. We present a novel microfluidic device based on the integration of printed circuit boards and an isotachophoresis assay for sample preparation of nucleic acids from biological samples. The device has integrated resistive heaters and temperature sensors as well ...
Harding Rosie - - 2012
This paper explores the legal position of the off-label prescription of antipsychotic medications to people with dementia who experience behavioural and psychological symptoms of dementia (BPSD). Dementia is a challenging illness, and BPSD can be very difficult for carers to manage, with evidence that this contributes to carer strain and ...
Siladke Nathan A - - 2012
The synthesis of mixed tethered alkyl uranium metallocenes has been investigated by examining the reactivity of the bis(tethered alkyl) metallocene [(η(5) -C(5) Me(4) SiMe(2) CH(2) -κC)(2) U] (1) with substrates that react with only one of the UC linkages. The effect of these mixed tether coordination environments on the reactivity ...
Bernhard B C - - 2012
Crossbred steers (n = 20; 235 ± 4 kg) were fed for 53 d during a receiving period to determine if supplementing chromium (Cr; KemTRACE®(brand)ChromiumPropionate 0.04%, Kemin Industries) would alter glucose or lipid metabolism of newly received cattle. Chromium premixes were supplemented to add 0 (Con) or 0.2 mg/kg of ...
Mårtensson J - - 2012
Acute kidney injury (AKI) has a number of triggers, including ischaemia, nephrotoxins, radiocontrast, and bacterial endotoxins. It occurs in around one-third of patients treated in intensive care unit (ICU) and is even more prevalent in cardiac surgery patients. There is a higher mortality in patients with AKI compared with non-AKI ...
Narvaez-Rosales Veronica - - 2012
Background  Transient myeloproliferative disorder (TMD) affects up to 10% of patients with Down syndrome (DS). A small proportion of newborns are asymptomatic and only manifest circulating blast cells, with or without leukocytosis, while others present with hepatomegaly, splenomegaly, serous effusions, and liver fibrosis. Few cases in the literature also have ...
Heller Laura E - - 2012
Controlling the self-assembly of thiophene-containing molecules and polymers requires a strong fundamental understanding of the relationship between molecular features and structure-directing forces. Here, the effects of ring-substitution position on the two-dimensional self-assembly of mono-substituted thiophenes at the phenyloctane/HOPG interface are studied using scanning tunneling microscopy (STM). The influence of π…π-stacking, ...
Börnigen Daniela - - 2012
MOTIVATION: Gene prioritization aims at identifying the most promising candidate genes among a large pool of candidates-so as to maximize the yield and biological relevance of further downstream validation experiments and functional studies. During the past few years, several gene prioritization tools have been defined and some of them have ...
Hempel Marek - - 2012
Here we report on the fabrication and characterization of a novel type of strain gauge based on percolative networks of 2D materials. The high sensitivity of the percolative carrier transport to strain induced morphology changes was exploited in strain sensors that can be produced from a wide variety of materials. ...
Liang Chen-Hsien - - 2012
α-catulin is oncoprotein that help sustains proliferation by preventing cellular senescence. Here we report that α-catulin also drives malignant invasion and metastasis. α-catulin was upregulated in highly invasive non-small cell lung cancer (NSCLC) cell lines, where its ectopic expression or shRNA-mediated attenuation enhanced or limited invasion or metastasis, respectively. α-catulin ...
Meng Weihua - - 2012
PURPOSE. Myopia is a complex trait affected by both genetic and environmental factors. High myopia is associated with increased risk of sight-threatening eye disorders such as retinal detachment. The purpose of this genome-wide association study was to identify susceptibility genes contributing to high myopia in the French population. METHODS. High ...
Polinski Matthew J - - 2012
Reactions of LnCl(3)·6H(2)O (Ln = La-Nd, Sm, Eu), concentrated (11 M) perchloric acid, and molten boric acid result in the formation of four different compounds. These compounds are Ln[B(8)O(10)(OH)(6)(H(2)O)(ClO(4))]·0.5H(2)O (Ln = La-Nd, Sm), Pr[B(8)O(11)(OH)(4)(H(2)O)(ClO(4))], Ln[B(7)O(11)(OH)(H(2)O)(2)(ClO(4))] (Ln = Pr, Nd, Sm, and Eu), and Ce[B(8)O(11)(OH)(4)(H(2)O)(ClO(4))]. All Ln(III) cations are ten-coordinate with ...
Dunberger Gail - - 2012
Every year medical researchers make contact with a large number of cancer survivors with the aim of evaluating cancer treatment. For this reason we decided to investigate how Swedish cancer survivors perceived their participation in research studies focusing on the long-term consequences of being a survivor of gynaecological or urinary ...
Takahashi Ryoji - - 2012
AbstractPurple-blue flower of soybean (Glycine max [L.] Merr.) is controlled by the W2 locus. Previous studies revealed that a MYB transcription factor gene GmMYB-G20-1 was located at a position similar to the W2 gene and that a base substitution generated a stop codon in the MYB domains of 2 soybean ...
Wang Xun - - 2012
The metal nanocrystals with high-index facets (HIFs) has drawn significant attention for their superior catalysis activity compared with low-index faces. However, due to the high surface energy of HIFs, it is still challenging to preserve HIFs during the growth of nanocrystal. In this study, the highly selective Pt concave nanocubes ...
Lommatzsch Marek - - 2012
Airway hyperresponsiveness (AHR) is the most characteristic clinical feature of asthma. The pathogenesis of AHR in asthma is characterized by a variety of epithelial, microbial, and inflammatory triggers on one hand and abnormalities of effector structures in the airways such as smooth muscle cells, blood vessels, and nerves on the ...
Christie John M - - 2012
Light is a key environmental factor that drives many aspects of plant growth and development. Phototropism, the reorientation of growth toward or away from light, represents one of these important adaptive processes. Modern studies of phototropism began with experiments conducted by Charles Darwin demonstrating that light perception at the shoot ...
Igci Mehri - - 2012
Cytokine-induced expression of suppressors of cytokine signalling (SOCS) molecules is important for the negative feedback control of STAT-dependent cytokine signalling. The aim of this study was to investigate possible association between the promoter region polymorphisms of the SOCS3 gene and metastatic colorectal carcinoma in a Turkish population. The DNA samples ...
Hyun Jerome K - - 2012
An elastomeric poly(dimethylsiloxane) (PDMS) block engraved with periodically arrayed nanopillars serves as a transferable light-trapping stamp for encapsulated organic thin-film solar cells. Diffracted light rays from the stamp interfere with one another and self-focus onto the active layer of the solar cell, generating enhanced absorption, as indicated in the current ...
Mohd Yusop Mohd Zamri - - 2012
In situ transmission electron microscopy (TEM) of single Fe-included carbon nanofibers (CNFs) revealed that the fine polycrystalline structure in the shank region of CNFs transformed to graphitic, hollow structures during a field emission (FE) process. The iron (Fe) metal platelets agglomerated during the FE process and perceptibly were emitted from ...
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