Search Results
Results 601 - 650 of 3014
< 8 9 10 11 12 13 14 15 16 17 18 >
Szram Joanna - - 2012
Population-based studies suggest that one in 10 cases of new, recurrent, or deteriorating asthma in adulthood is related to the workplace environment. Nonspecific, irritant exposures at work can upset symptom control in pre-existing disease (work-exacerbated asthma); where disease arises de novo from the workplace (occupational asthma) it generally has an ...
Lee Young Ho - - 2012
OBJECTIVE: The aim of this study was to determine whether the insertion (I) /deletion (D) polymorphism within intron 16 of angiotensin-converting enzyme (ACE) confers susceptibility to systemic lupus erythematosus (SLE) and lupus nephritis (LN). METHODS: A meta-analysis was conducted on the associations between the ACE I/D polymorphism and SLE and ...
Karatas Ilhami - - 2012
The effects of long-term drought stress on chlorophyll, proline, protein and hydrogen peroxide (H(2)O(2)) contents, malondialdehyde (MDA) in terms of lipid peroxidation and on the changes in the activities of antioxidant enzymes such as superoxide dismutase (SOD, EC 1.15.1.1), ascorbate peroxidase (APX, EC 1.11.1.11), catalase (CAT, EC 1.11.1.6) and peroxidase ...
Wrzodek Clemens - - 2012
MOTIVATION: Traditionally, microarrays were almost exclusively employed for the genome-wide analysis of differential gene expression. But nowadays, their scope of application has been extended to various genomic features, such as microRNAs, proteins, and DNA methylation. Most available methods for the visualization of these datasets are focused on individual platforms and ...
Enguidanos Susan - - 2012
Abstract Background: Inpatient palliative consultation are generally provided to seriously ill hospitalized patients with the intent to alleviate pain and suffering and develop a plan of care for the patient. Although numerous benefits of this service have been documented, little is known about hospital readmission rates and factors associated with ...
Ertuğrul Sabahattin - - 2012
Abstract Objective: We aimed to determine the value of uNGAL levels in the early diagnosis of late-onset sepsis in preterms, and to compare CRP and PCT. Materials and Methods: Preterm infants admitted to the NICU between the ages of 7 to 28 days, were divided into two groups: 24 cases ...
Huis In 't Veld Diana - - 2012
ABSTRACT: BACKGROUND: Alcohol abuse comes with risks for increased morbidity and mortality among patients with HIV. This study aims to determine the prevalence of alcohol use and other risk factors in a sample of primary care patients with HIV in South Africa and to assess a brief intervention to reduce ...
Holmes Alison Volpe - - 2012
Abstract Background and Objectives: Lack of physician knowledge about breastfeeding is associated with decreased initiation and continuation of breastfeeding by patients. We evaluated the effects of a breastfeeding education program on physicians' breastfeeding knowledge, attitudes, and beliefs, measured changes in clinical practice, and examined breastfeeding rates of patients of participating ...
Chen Chang - - 2012
Wastewater analysis has the potential to provide objective and timely data on population drug consumption, but some crucial factors such as pre-analysis drug loss during sample storage and filtration could affect the accuracy and reliability of the method, and these uncertainties have yet to be fully assessed. This study was ...
De Cosmo S - - 2012
Several lines of evidence suggest a pathogenic role of insulin resistance on kidney dysfunction. Potential mechanisms are mostly due to the effect of single abnormalities related to insulin resistance and clustering into the metabolic syndrome. Hyperinsulinemia, which is inevitably associated to insulin resistance in non diabetic states, also appears to ...
Okumi Hirokuni - - 2012
Capsaicin and 6-gingerol, pungent components of chilli pepper and ginger, are known as dietary agonists of transient receptor potential vanilloid-1. Transient receptor potential vanilloid-1 nerve fibers are recognized to play a role in gastric mucosal integrity in rats. In the present studies, we examined the acute effects of peroral administration ...
Gao Qi - - 2012
Rationale: Apoptosis and fatty acid-binding protein-4 (FABP4) induced-endoplasmic reticulum (ER) stress in macrophage is an important pathological process in several vascular occlusive diseases, including atherosclerosis, both of which are accelerated by lipids or inflammatory cytokines. Objective: To determine whether interleukin 17A (IL-17A) accelerates atherosclerosis through activating FABP4-mediated ER stress in ...
Vagiri Michael Rajeev - - 2012
Although the fruits are the economic driver for the black currant industry, the buds and leaves are excellent sources of beneficial phenolic compounds that may contribute to the future value of the crop. In this study, extraction of phenolic compounds for different parts of the black currant plant was optimized ...
Virchow J Christian - - 2012
Asthma is a chronic inflammatory condition affecting up to 10% of all women of child-bearing age. In most patients asthma can be safely treated during pregnancy. However, asthma crises or exacerbations during pregnancy can be life threatening to both the mother and the child. Uncontrolled asthma has been associated with ...
Baldwin Katherine L - - 2012
During gravitropism, the potential energy of gravity is converted into a biochemical signal. How this transfer occurs remains one of the most exciting mysteries in plant cell biology. New experiments are filling in pieces of the puzzle. In this review, we introduce gravitropism and give an overview of what we ...
Liu Qian - - 2012
Currently, concerns of clopidogrel and proton pump inhibitors (especially omeprazole) interaction are raised, because they are both metabolized by CYP2C19. What is more, omeprazole can also inhibit the activity of CYP2C19. The study was to compare the influence of omeprazole on platelet inhibition of clopidogrel in various CYP2C19 mutant alleles. ...
Farmer Jennifer Lynn - - 2012
The cross-coupling of allylpinacolboronic ester derivatives with aryl and heteroaryl halides occurred with high selectivity (>97%) at the α-carbon of the allylboron reagent in the presence of Pd-PEPPSI-IPent precatalyst and 5M KOH in refluxing THF. In case of trisubstituted E-allylboronates, mi-nor olefin geometry isomerization was observed (E/Z ~ 80/20).
McCann Dustin A - - 2012
A 69 year old white male presented to a tertiary hospital from a skilled nursing facility with malaise, fatigue, night sweats, and a non-productive cough for seven days.. He was a retired Midwestern farmer who lived near a fresh water stream, and a remote former smoker. There had been no ...
Wang Teng - - 2012
Hot couple: Propargyl azides were coupled with carboxylic acids by an iron-catalyzed dehydrogenative CO bond formation. This method enables propargylic C sp 3H functionalization under mild reaction conditions and also may involve the application of the azido moiety as an assisting group in CH activation.
Pollin Reiko - - 2012
Lyssavirus matrix proteins (M) support virus budding and have accessory functions that may contribute to host cell manipulation and adaptation to specific hosts. Here, we show that rabies virus (RABV) and European Bat Lyssavirus Type 1 (EBLV-1) M proteins differ in targeting and accumulation at cellular membranes. In contrast to ...
Hatfield Kimberley J - - 2012
Increased bone marrow angiogenesis is seen in several hematological malignancies, including acute myeloid leukemia (AML). We used a co-culture assay of endothelial and vascular smooth muscle cells to investigate the effects of AML-conditioned medium on capillary networks. We investigated primary AML cells derived from 44 unselected patients and observed that ...
Wadsworth Andrew D - - 2012
The total syntheses of the initially reported and revised structures of the neuroprotective agent palmyrolide A are reported. The key macrocyclization step was achieved using a sequential ring closing metathesis/olefin isomerization reaction. The synthetic work described herein serves to confirm the recent structural revision of this unusual natural product.
Gravel Dominique - - 2012
There is consensus that biodiversity losses will result in declining ecosystem functioning if species have different functional traits. Phylogenetic diversity has recently been suggested as a predictor of ecosystem functioning because it could approximate the functional complementarity among species. Here we describe an experiment that takes advantage of the rapid ...
Tan Feng - - 2012
Proteomic analysis allows detection of changes of proteins expression in organisms exposed to environmental pollutants, leading to the discovery of biomarkers of exposure and understanding of the action mechanism of toxicity. In the present study, we applied iTRAQ labeling quantitative proteomic technology for global characterization of the liver proteome in ...
Thompson Sanna J - - 2012
This study examined the direct effects of physical and sexual abuse, neglect, poor family communication and worries concerning family relationships, depression, anxiety, and dissociation on posttraumatic stress symptoms. Runaway youth were recruited from emergency youth shelters in New York and Texas. Interviews were completed with 350 youth who averaged 15 ...
Yadav Prasad - - 2012
Thumbs up for porous graphene! Single-layer-graphene-assembled 3D hexaporous carbon is prepared by catalyst-free pyrolysis of poly(4-styrenesulfonic acid-co-maleic acid) sodium salt. The material has a hierarchical structure of mesoporous as well as microporous graphene with hexagonal nanopores of uniform size and shape. The results show that the sample is highly conducting ...
Selvaraj M - - 2012
We demonstrate a much green synthesis method for highly selective synthesis of 6,8-di-t-butylated flavan (6,8-DTBF) by liquid phase alkylation of 2,4-di-t-butylphenol (2,4-DTBP) with cinnamyl alcohol (Cin-OH) over mesoporous Zn-Al-MCM-41 catalysts synthesized under direct basic hydrothermal method. The main alkylated product, 6,8-DTBF is importantly used as an intermediate in the manufacture ...
Zhao Yao - - 2012
Two photons are better than one: A square-planar Pt(II) complex with derivatized pyridine ligands was synthesized, which undergoes two-photon-induced ligand substitution with 600-740 nm light. Linear and quadratic density functional response theory allowed identification of the electronic transitions involved.
Beh Maia M - - 2012
The first wildfires in sudden oak death-impacted forests occurred in 2008 in the Big Sur region of California, creating the rare opportunity to study the interaction between an invasive forest pathogen and a historically recurring disturbance. To determine whether and how the sudden oak death pathogen, Phytophthora ramorum, survived the ...
Hakeem Khalid Rehman - - 2012
Abstract Plant growth and productivity are influenced by various abiotic stresses. Stressful conditions may lead to delays in seed germination, reduced seedling growth, and decreased crop yields. Plants respond to environmental stresses via differential expression of a subset of genes, which results in changes in omic compositions, such as transcriptome, ...
Andolfi Anna - - 2012
Two isolates of Neofusicoccum australe belonging to ITS haplotypes H4 and H1 and associated with grapevine cordon dieback and branch dieback of Phoenicean juniper, respectively, have been shown to produce in vitro structurally different secondary metabolites. From the strain BOT48 of N. australe (haplotype H4) a new cyclohexenone oxide, namely, ...
Murgiano Leonardo - - 2012
ABSTRACT: BACKGROUND: Bovine congenital pseudomyotonia (PMT) is an impairment of muscle relaxation induced by exercise preventing animals from performing rapid movements. Forms of recessively inherited PMT have been described in different cattle breeds caused by two independent mutations in ATP2A1 encoding a skeletal-muscle Ca2+-ATPase (SERCA1). We observed symptoms of congenital ...
Switlyk Md - - 2012
BackgroundMagnetic resonance imaging (MRI) is the recommended primary investigation method for metastatic spinal cord compression (MSCC). Initiating treatment before the development of motor deficits is essential to preserve neurological function. However, the relationship between MRI-assessed grades of spinal metastatic disease and neurological status has not been widely investigated.PurposeTo analyze the ...
Hu Guoping - - 2012
This study aims to identify inhibitors that bind at the interface of HIV-1 integrase and human LEDGF/p75, which represents a novel target for anti-HIV therapy. To date, only a few such inhibitors have been reported. Here structure-based virtual screening was performed to search for the inhibitors from an in-house library ...
Ralston Shawn - - 2012
BACKGROUND: Acute viral bronchiolitis is the most common diagnosis resulting in hospital admission in pediatrics. Utilization of non-evidence-based therapies and testing remains common despite a large volume of evidence to guide quality improvement efforts. OBJECTIVE: Our objective was to reduce utilization of unnecessary therapies in the inpatient care of bronchiolitis ...
Randall J - - 2012
Background. Human rights violations are commonly experienced by people in psychiatric and social care institutions. States and private organizations providing such health and social services must comply with international human rights law. Monitoring of such compliance is increasingly recognized as a vital component in ensuring that rights are respected and ...
Reid E D - - 2012
Early detection of disease can speed treatment, slow the spread of disease in a herd, and improve the health status of animals. Immune stimulation elevates rectal temperature (RT). Injectable radio frequency implants (RFI) can provide temperature at the site of implantation. The fidelity of peripheral site temperature, determined by RFI, ...
Y Wang Christina - - 2012
Objective: To review immunologic contact urticaria (ICU) in the occupational and environmental context, and describe its continued relevance in light of the ever-increasing onslaught of new chemicals and products, as well as new technology placing novel interactions, such as nanoparticles, within reach of the population at home and work. Methods: ...
Tobe Makoto - - 2012
OBJECTIVE The National Health Insurance Program (NHIP) in the Philippines is a social health insurance system partially subsidized by tax-based financing which offers benefits on a fee-for-service basis up to a fixed ceiling. This paper quantifies the extent to which beneficiaries of the NHIP incur out-of-pocket expenses for inpatient care, ...
Giesing Michael - - 2012
What's known on the subject? and What does the study add? The role of circulating cancer cells in metastogenesis is generally accepted. Two forms of these cells have been reported in a number of studies, cancer cell clusters (CCCs) and individual epithelial cancer cells. Clusters appear at higher frequencies in ...
Foresta C - - 2012
Background: Recent data suggest a potential role of testis in vitamin D activation, where Leydig cells could represent key players in this process since they express the highest amount of CYP2R1, a key enzyme involved in vitamin D 25- hydroxylation. Aim: To evaluate bone status in unilateral orchiectomy and to ...
Lotta Ingrid Astrid - - 2012
Abstract Leucocytozoon spp. infections have been rarely studied in Neotropical countries. The apparent low prevalence of these parasites compared to the Nearctic regions, suggests the absence of competent vectors in this geographical region; however a 21.3% overall prevalence has recently been reported in non-migratory birds from the paramo region of ...
Martirosyan Varsik - - 2012
The aim of the present work was to investigate the frequency-dependent effects of mechanical vibration at infrasound frequency (MV at IS frequency or MV) on E. coli K-12 growth by investigating the cell proliferation, using radioactive [(3)H]-thymidine assay. The frequency-dependent effects of MV were shown that it could either stimulate ...
Armistead-Jehle Patrick - - 2012
The study examined Symptom Validity Test (SVT) performance in a sample of military service members on active orders as a function of evaluation context. Service members were assessed in the context of either a pending disability evaluation (Medical Evaluation Board; MEB) or a non-MEB/clinical evaluation. Overall, 41.8% of the sample ...
Ma Da - - 2012
Be My Guest: Two acyclic cucurbit[n]uril-type receptors that carry SO(3) (-) -groups bind tightly to several commonly used neuromuscular blocking agents, such as rocuronium, in aqueous solution as revealed by direct and competitive UV/Vis binding assays. One of these containers functions as a potent reversal agent for rocuronium-induced neuromuscular block ...
Chi Celestine N - - 2012
The PDZ domain is a protein-protein interaction module with a shallow binding groove where protein ligands bind. However, interactions that are not part of this canonical binding groove are likely to modulate peptide binding. We have investigated such interactions beyond the binding groove for PDZ3 from PSD-95 and a peptide ...
Phillips P S - - 2012
Aim: To assess the clinical and radiological characteristics of the posterior prolongation of the cartilaginous nasal septum, an under-utilised source of autologous cartilage for nasal reconstruction. Materials and methods: Consecutive patients undergoing primary, external approach rhinoplasty were included. The septal cartilage was assessed intra-operatively prior to routine harvest. Cartilage use ...
Bartz M - - 2012
Fatty acid composition in porcine intramuscular fat affects the dietetic value and technological properties of meat. The stearoyl-CoA desaturase (SCD) gene is a strong positional and functional candidate for fatty acid composition. Our sequence analysis in 4 breeds (Duroc, Pietrain, Polish Landrace, and Polish Large White) revealed a novel single-nucleotide ...
Agudelo Carlos A - - 2012
Magnetic resonance imaging is one of the most important fields for cellular imaging due to its non-invasive capacity, spatial resolution, and sensibility to visualized transplanted cells. An enhanced magnetic resonance image can be achieved by using contrast agents containing paramagnetic gadolinium chelates, which have the widest clinical use. To obtain ...
Yan Juan - - 2012
Although "hot spots" have been proved to contribute to surface enhanced Raman scattering (SERS), less attention was paid to increase the number of the "hot spot" to directly enhance the Raman signals in bioanalytical systems. Here we report a new strategy based on nano-rolling circle amplification (nanoRCA) and nano-hyperbranched rolling ...
< 8 9 10 11 12 13 14 15 16 17 18 >