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Barrett Helen L HL UQ Centre for Clinical Research, University of Queensland, Herston, Queensland, Australia. - - 2013
This study was designed to compare glucose, lipids, and C-reactive protein (CRP) in women with gestational diabetes mellitus treated with metformin or insulin and in cord plasma of their offspring and to examine how these markers relate to infant size at birth. Women with gestational diabetes mellitus were randomly assigned ...
Michaleff Zoe A - - 2012
There is uncertainty about the optimal approach to screen for clinically important cervical spine (C-spine) injury following blunt trauma. We conducted a systematic review to investigate the diagnostic accuracy of the Canadian C-spine rule and the National Emergency X-Radiography Utilization Study (NEXUS) criteria, 2 rules that are available to assist ...
Ito Chiharu - - 2012
Proteinuria is common adverse effect that occurs after the use of bevacizumab, but it occurs rarely during administration of cetuximab. We report the first case of nephrotic syndrome induced by cetuximab after completing mFOLFOX6 with bevacizumab followed by sLV5FU2 with bevacizumab for metastatic rectal cancer. Prior to the administration of ...
El-Gendy Reem - - 2012
The increasing clinical demand for bone substitutes has driven significant progress in cell based therapies for bone tissue engineering. The underpinning goals for success are to identify the most appropriate cell source and to provide 3D scaffolds that support cell growth and enhance osteogenic potential. In this study, human dental ...
Szram Joanna - - 2012
Population-based studies suggest that one in 10 cases of new, recurrent, or deteriorating asthma in adulthood is related to the workplace environment. Nonspecific, irritant exposures at work can upset symptom control in pre-existing disease (work-exacerbated asthma); where disease arises de novo from the workplace (occupational asthma) it generally has an ...
Battaglia Gina M GM Department of Kinesiology, College of Health and Human Performance, East Carolina University, Greenville, NC 27858, - - 2012
Obese individuals typically exhibit a reduced capacity for metabolic flexibility by failing to increase fatty acid oxidation (FAO) upon the imposition of a high-fat diet (HFD). Exercise training increases FAO in the skeletal muscle of obese individuals, but whether this intervention can restore metabolic flexibility is unclear. The purpose of ...
Lee Young Ho - - 2012
OBJECTIVE: The aim of this study was to determine whether the insertion (I) /deletion (D) polymorphism within intron 16 of angiotensin-converting enzyme (ACE) confers susceptibility to systemic lupus erythematosus (SLE) and lupus nephritis (LN). METHODS: A meta-analysis was conducted on the associations between the ACE I/D polymorphism and SLE and ...
Karatas Ilhami - - 2012
The effects of long-term drought stress on chlorophyll, proline, protein and hydrogen peroxide (H(2)O(2)) contents, malondialdehyde (MDA) in terms of lipid peroxidation and on the changes in the activities of antioxidant enzymes such as superoxide dismutase (SOD, EC 1.15.1.1), ascorbate peroxidase (APX, EC 1.11.1.11), catalase (CAT, EC 1.11.1.6) and peroxidase ...
Wrzodek Clemens - - 2012
MOTIVATION: Traditionally, microarrays were almost exclusively employed for the genome-wide analysis of differential gene expression. But nowadays, their scope of application has been extended to various genomic features, such as microRNAs, proteins, and DNA methylation. Most available methods for the visualization of these datasets are focused on individual platforms and ...
Badger Terry A TA College of Nursing, The University of Arizona, Tucson, AZ, - - 2013
We examined selected survivor characteristics to determine what factors might moderate the response to two psychosocial interventions. Seventy-one prostate cancer survivors (PCSs) were randomly assigned to either a telephone-delivered health education (THE) intervention or a telephone-delivered interpersonal counselling (TIP-C) intervention. Psychological quality of life (QOL) outcomes included depression, negative and ...
Enguidanos Susan S University of Southern California, Leonard Davis School of Gerontology, Los Angeles, California 90089-0191, USA. - - 2012
Inpatient palliative consultation are generally provided to seriously ill hospitalized patients with the intent to alleviate pain and suffering and develop a plan of care for the patient. Although numerous benefits of this service have been documented, little is known about hospital readmission rates and factors associated with these readmissions. ...
Ertuğrul Sabahattin - - 2012
Abstract Objective: We aimed to determine the value of uNGAL levels in the early diagnosis of late-onset sepsis in preterms, and to compare CRP and PCT. Materials and Methods: Preterm infants admitted to the NICU between the ages of 7 to 28 days, were divided into two groups: 24 cases ...
Huis In 't Veld Diana - - 2012
ABSTRACT: BACKGROUND: Alcohol abuse comes with risks for increased morbidity and mortality among patients with HIV. This study aims to determine the prevalence of alcohol use and other risk factors in a sample of primary care patients with HIV in South Africa and to assess a brief intervention to reduce ...
Holmes Alison Volpe - - 2012
Abstract Background and Objectives: Lack of physician knowledge about breastfeeding is associated with decreased initiation and continuation of breastfeeding by patients. We evaluated the effects of a breastfeeding education program on physicians' breastfeeding knowledge, attitudes, and beliefs, measured changes in clinical practice, and examined breastfeeding rates of patients of participating ...
Chen Chang - - 2012
Wastewater analysis has the potential to provide objective and timely data on population drug consumption, but some crucial factors such as pre-analysis drug loss during sample storage and filtration could affect the accuracy and reliability of the method, and these uncertainties have yet to be fully assessed. This study was ...
De Cosmo S - - 2012
Several lines of evidence suggest a pathogenic role of insulin resistance on kidney dysfunction. Potential mechanisms are mostly due to the effect of single abnormalities related to insulin resistance and clustering into the metabolic syndrome. Hyperinsulinemia, which is inevitably associated to insulin resistance in non diabetic states, also appears to ...
Okumi Hirokuni - - 2012
Capsaicin and 6-gingerol, pungent components of chilli pepper and ginger, are known as dietary agonists of transient receptor potential vanilloid-1. Transient receptor potential vanilloid-1 nerve fibers are recognized to play a role in gastric mucosal integrity in rats. In the present studies, we examined the acute effects of peroral administration ...
Gao Qi Q Department of Immunology, Shandong University School Medicine, Shandong, P.R. - - 2012
Apoptosis and fatty acid-binding protein-4 (FABP4) induced-endoplasmic reticulum (ER) stress in macrophage is an important pathological process in several vascular occlusive diseases, including atherosclerosis, both of which are accelerated by lipids or inflammatory cytokines. To determine whether interleukin 17A (IL-17A) accelerates atherosclerosis through activating FABP4-mediated ER stress in macrophage. We ...
Vagiri Michael Rajeev - - 2012
Although the fruits are the economic driver for the black currant industry, the buds and leaves are excellent sources of beneficial phenolic compounds that may contribute to the future value of the crop. In this study, extraction of phenolic compounds for different parts of the black currant plant was optimized ...
Schramm A - - 2012
Using mRNA expression-derived signatures as predictors of individual patient outcome has been a goal ever since the introduction of microarrays. Here, we addressed whether analyses of tumour mRNA at the exon level can improve on the predictive power and classification accuracy of gene-based expression profiles using neuroblastoma as a model. ...
Muscat Martina - - 2012
Background: Calciphylaxis is a rare condition characterized by calcification of the tunica media of small arteries with or without endovascular fibrosis, extravascular calcification and vascular thrombosis, leading to tissue ischemia and hence necrosis of tissues supplied by respective vessel. Case report: An 83-year-old lady presented with a 2-week history of ...
An Rong - - 2012
A simple physical strategy to reduce the frictional and adhesive forces on TiO2 films was proposed by constructing mesoporous TiO2 films with heterogeneously distributed nanopores on the film surfaces. In comparison, TiO2 films with densely-packed nanoparticles were also prepared. The crystal structure and morphology of the films were characterized with ...
El Kadiri Moulay Youness - - 2012
Water, a powerful ally: A Mn(III) complex with an N(4) O-coordinating ligand and a deprotonated water molecule as sixth ligand is chemically oxidized by a Ce(IV) one-electron oxidant. The results indicate catalytic oxygen atom transfer to alkenes, with the oxygen atom originating from a water molecule. These findings demonstrate the ...
Zaluzhna Oksana - - 2012
Inverse-micelle-encapsulated water formed in the two-phase Brust-Schiffrin method (BSM) synthesis of Au nanoparticles (NPs) is identified as essential for dialkyl diselenide/disulfide to react with the Au(III) complex in which the Se-Se/S-S bond is broken, leading to formation of higher-quality Au NPs.
Herrmann Anders - - 2012
Orellanine is a nephrotoxin found in various Cortinaceae mushroom species. Unintentional consumption after these species were confused with edible mushrooms such as Cantharellus tubaeformis has caused several casualties. In this work, a quantitative HPLC-ESI-MS/MS method for total orellanine in Cortinarius rubellus, spiked blood plasma, and a mushroom stew prepared from ...
Shirai Soichi - - 2012
Paracyclophanes are simple idealized model molecules for the study of interacting π-stacking systems. In this study, the excited states of [2.2]paracyclophane ([2.2]PCP), [3.3]paracyclophane ([3.3]PCP), and siloxane-bridged paracyclophane (SiPCP) are systematically investigated using the multiconfiguration quasi-degenerated perturbation theory (MCQDPT) method. The excited states of the alkyl- and silyl-substituted benzene monomers and ...
Sureddi Ravi K - - 2012
OBJECTIVES: Atrial fibrillation (AF) often develops in patients with multiple myeloma following autologous stem cell transplantation (ASCT), but the exact incidence of, and the risk factors for AF have not been described. In this study, we sought to determine the incidence of AF in patients with multiple myeloma undergoing ASCT. ...
Chang Eric Y - - 2012
Purpose:To determine the prevalence of magnetic resonance (MR) imaging abnormalities after metal-on-metal total hip arthroplasty and to determine whether presence of symptoms correlates with findings at MR imaging.Materials and Methods:This HIPAA-compliant study was approved by the institutional review board, and informed consent was waived. MR imaging was performed with conventional ...
Orava Erik W - - 2012
Tumour necrosis factor-alpha (TNFα) is a pivotal component of the cytokine network linked to inflammatory diseases. Protein-based, TNFα inhibitors have proven to be clinically valuable. Here, we report the identification of short, single stranded DNA aptamers that bind specifically to TNFα. One such 25-base long aptamer, termed VR11, was shown ...
Alshatwi Ali A - - 2012
An urgent need for toxicological studies on aluminium oxide nanoparticles (Al(2) [Formula: see text]NPs) has arisen from their rapidly emerging range of applications in the food and agricultural sectors. Despite the widespread use of nanoscale aluminium and its composites in the food industry, there is a serious lack of information ...
Zorrilla-Rios J M - - 2012
Twenty three thousand four hundred eighty four beef carcasses were classified according to the Mexican norm NMX-FF-078-SCFI-2002 at the No 51 Federal Inspected Type abattoir located in the State of Tabasco, Mexico, owned by the Beef Cattle Union of Tabasco State. Tabasco State has a Tropical humid (Am) and sub-humid ...
Green Jennifer C - - 2012
Although compounds that feature 3-centre 2-electron (3c-2e) bonds are well known, there has been no previous effort to classify the interactions according to the number of electrons that each atom contributes to the bond, in a manner analogous to the classification of 2-centre 2-electron (2c-2e) bonds as either normal covalent ...
Herreria-Bustillo Vicente J - - 2012
A 3-year-old domestic shorthair cat was witnessed ingesting mushrooms and developed signs of muscarine intoxication. After stabilisation and treatment with atropine the cat recovered well and was discharged from hospital in 2 days. This report describes the features and successful management of this unusual toxicosis in cats.
Ormiston John A - - 2012
BACKGROUND: NONSERIAL OBSERVATIONS HAVE SHOWN THIS BIORESORBABLE SCAFFOLD TO HAVE NO SIGNS OF AREA REDUCTION AT 6 MONTHS AND RECOVERY OF VASOMOTION AT 1 YEAR. SERIAL OBSERVATIONS AT 6 MONTHS AND 2 YEARS HAVE TO CONFIRM THE ABSENCE OF LATE RESTENOSIS OR UNFAVORABLE IMAGING OUTCOMES.METHODS AND RESULTS: THE ABSORB TRIAL ...
Littlefield Benjamin T R - - 2012
Nanoporous materials have important industrial applications as molecular sieves, catalysts and in gas separation and storage. They are normally produced as moderately dense silicates (SiO(2)) and aluminosilicates making their specific capacities for the uptake and storage of gases, such as hydrogen, relatively low. Here we report the synthesis and characterization ...
Shui Jiang-Lan - - 2012
Using a microfocused synchrotron X-ray diffraction (μ-XRD) method, we systematically investigated the distributions of insoluble lithium precipitates, which formed through electrolyte decomposition, separately in all three regions (cathode, separator, and anode) of failed batteries with a spatial resolution of 20 μm. We found unexpectedly that there was a significantly higher concentration ...
Aung Kyaw - - 2012
Dynamin-related proteins (DRPs) are key components of the organelle division machineries, functioning as molecular scissors during the fission process. In Arabidopsis, DRP3A and DRP3B are shared by peroxisomal and mitochondrial division, whereas the structurally-distinct DRP5B (ARC5) protein is involved in the division of chloroplasts and peroxisomes. Here, we further investigated ...
Sarma Nayan J NJ Department of Surgery, Washington University School of Medicine, St. Louis, MO, - - 2012
Transcriptional regulation is a complex process that requires the integrated action of many multi-protein complexes. The way in which a living cell coordinates the action of these complexes in time and space is still poorly understood. Recent work has shown that nuclear pores, well known for their role in 3' ...
Valizadeh H - - 2012
In the present study pharmacokinetics and bioequivalence of 2 brands of ciprofloxacin 500 mg were evaluated in 24 healthy male volunteers after a single dose oral administration in an open, randomized, 2-way crossover study.Blood samples were taken before and within 12 h after the administration of the drug. Plasma concentrations of ciprofloxacin ...
Wang Xu-Dong - - 2012
Living color: Fluorescent pH-sensitive nanoparticles 12 nm in diameter were prepared and incorporated into agarose gel in a Petri dish to image pH changes during bacterial growth and metabolism.
Das Suresh - - 2012
Star-shaped molecules consisting of a 1, 3, 4-oxadiazole core derivatized with alkoxy substituted phenyl ethynylenes, FD12 (dodecyl) and FD16 (hexadecyl) were synthesized. These molecules exhibited enantiotropic columnar mesophases over a wide temperature range, with the liquid crystalline phases exhibiting strong blue fluorescence. On cooling FD12 transformed into a transparent glass ...
Compare Angelo - - 2012
Background: Binge eating disorder (BED) is a complex and multifaceted eating disorder and the literature indicates that BED patients show greater difficulty identifying and making sense of emotional states, and that they have limited access to emotion regulation strategies. Findings show many links between mindfulness and emotional regulation however there ...
Race Margaret - - 2012
Abstract This paper reports recent efforts to gather experts from the humanities and social sciences along with astrobiologists to consider the cultural, societal, and psychological implications of astrobiology research and exploration. We began by convening a workshop to draft a research roadmap on astrobiology's societal implications and later formed a ...
Venugopal Ram Rao - - 2012
A 36-year old woman presented with a 5-year history of progressive dysphagia. The barium swallow of the oesophagus revealed an oblique extrinsic defect consistent with an aberrant right subclavian artery. A computed tomography angiogram confirmed the diagnosis. Surgical correction is indicated for dysphagia lusoria in association with an aberrant right ...
Sejersen H - - 2012
We have investigated the liver response in young pigs to a high-fat diet (containing 25% animal fat) and diet restriction (equivalent to 60% of maintenance) using differential proteome analysis. The objective was to investigate whether young pigs can be used to model the liver response in adolescents to a high-fat ...
Mackay J - - 2012
Objectives of this study were: (i) to compare fatty acid composition of subcutaneous adipose tissue of entire boars, barrows, and male pigs vaccinated against boar taint with a vaccine containing a GnRH analogue-protein conjugate (Improvac, Pfizer Animal Health), and (ii) to investigate the association between fatty acid composition and protein ...
Ashe Leah M - - 2012
Public health nutrition sits at the nexus of a global crisis in food, environmental and health systems that has generated - along with numerous other problems - an urgent and changing problem of food insecurity. The 'new' food insecurity, however, is different from the old: it is bimodal, encompassing issues ...
Nihei Yoshihiro Y Department of Neurology, School of Medicine, Keio University, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, - - 2012
The RNA-binding proteins TDP-43 and Fused in Sarcoma (FUS) play central roles in neurodegeneration associated with amyotrophic lateral sclerosis and frontotemporal lobar degeneration. Both proteins are components of messenger ribonucleoprotein (mRNP) granules and show cytoplasmic mislocalization in affected tissues. Recently, ataxin-2 was identified as a potent modifier of TDP-43 toxicity ...
Kurita Rei - - 2012
Often experimentalists study particulate samples that are nominally monodisperse. In reality, many samples have a polydispersity of 4-10%. At the level of an individual particle, the consequences of this polydispersity are unknown as it is difficult to measure an individual particle size from images of a dense sample. Here we ...
Pépin Geneviève - - 2012
The ribonuclease Dicer plays a central role in the microRNA pathway by catalyzing the formation of microRNAs, which are known to regulate messenger RNA (mRNA) translation. In order to improve our understanding of the molecular context in which Dicer functions and how it is regulated in human cells, we sought ...
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