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Results 251 - 300 of 2040
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Schagdarsurengin Undraga - - 2012
An understanding of the epigenetic mechanisms involved in sperm production and their impact on the differentiating embryo is essential if we are to optimize fertilization and assisted reproduction techniques in the future. Male germ cells are unique in terms of size, robustness, and chromatin structure, which is highly condensed owing ...
Ochodnicky Peter - - 2012
Increased voiding frequency and urgency are among the most prevalent storage lower urinary tract symptoms (LUTS), often diagnosed as part of overactive bladder syndrome (OAB). It has been suggested that these symptoms are caused by excessive sensory activation of the neural micturition circuit. It seems likely that sensory pathway remodelling ...
Xu Fang - - 2012
This manuscript first describes a simple synthesis of tungsten oxide (WO(x)) nanorods from templated W foil using a chemical vapour deposition (CVD) technique at 600-750 °C, then presents the formation of tungsten oxynitride (WO(x)N(y)) nanorods via nitridation at 650 °C for different reaction times. The W foil, blade engraved, acid ...
Pang Maolin - - 2012
Structures of Gold: A simple transformative method for nanoscale sculpturing has been developed. Five different types of complex nanocomposites of cuprite and gold have been formed by using this self-etching approach.
Fluttert Frans Aj - - 2012
AIMS AND OBJECTIVES: The Forensic Early Warning Signs of Aggression Inventory (FESAI) was developed to assist nurses and patients in identifying early warning signs and constructing individual early detection plans (EDP) for the prevention of aggressive incidents. The aims of this research were as follows: First, to study the prevalence ...
Bieberle-Hütter A - - 2012
An integrated system of a microreformer and a carrier allowing for syngas generation from liquefied petroleum gas (LPG) for micro-SOFC application is discussed. The microreformer with an overall size of 12.7 mm × 12.7 mm × 1.9 mm is fabricated with micro-electro-mechanical system (MEMS) technologies. As a catalyst, a special ...
Vignolini Silvia - - 2012
The Mediterranean orchid genus Ophrys is remarkable for its pseudocopulatory pollination mechanism; naïve male pollinators are attracted to the flowers by olfactory, visual and tactile cues. The most striking visual cue is a highly reflective, blue speculum region at the centre of the labellum, which mimics the corresponding female insect ...
Bergamasco M D - - 2012
Candidemia in cancer patients may differ according to the type of cancer. To characterise the epidemiology and outcome of candidemia in cancer patients from Brazilian hospitals, we compared the characteristics of patients with hematologic malignancies (HM) and solid tumours (ST). A retrospective study was performed, based on data collected from ...
Stock E - - 2012
A novel concept for on-chip quantum optics using an internal electrically pumped microlaser is presented. The microlaser resonantly excites a quantum dot microcavity system operating in the weak coupling regime of cavity quantum electrodynamics. This work presents the first on-chip application of quantum dot microlasers, and also opens up new ...
Tao L - - 2012
BACKGROUND:CYR61 (cysteine-rich protein 61, also named IGFBP10) is a secreted signaling molecule that promotes angiogenesis and tumor growth. The goal of this study is to determine whether a functional polymorphism in the promoter region of the CYR61 gene (rs3753793) is associated with prostate cancer (PCa) risk and gene expression in ...
Furlotti Guido - - 2012
Since the discovery of 5-HT4R a large number of receptor ligands have been studied. The safety concerns and the lack of market success of these ligands have mainly been attributed to their lack of selectivity. In this study we describe the discovery of N-[(4-piperidinyl)methyl]-1H-indazole-3-carboxamide and 4-[(4-piperidinyl)methoxy]-2H-pyrrolo[3,4-c]quinoline derivatives as new 5-HT4R ...
Li Feng - - 2012
Fluorination: A wide range of nitroolefins and pyrazol-5-ones undergo a sequential 1,4-addition/dearomative-fluorination transformation when treated with a catalytic amount of a tertiary-amine-thiourea compound and the terminal electrophile, N-fluorobenzenesulfonimide to give fluorinated products in 72-95 % yield with up to 99:1 d.r. and 98 % ee. Notably, these products contain adjacent tertiary and α-fluoro ...
Concina Isabella - - 2012
Growth kinetics of CdSe nanocrystals generated inside three selected polymers (polyvinylpyrrolidone - PVP, polyethyleneglycol - PEG and polyvinylalcohol - PVA) are demonstrated to follow a self-catalytic path, with growth rates depending on the nature of the polymer, i.e. on the capability to activate the cadmium species present in the solution ...
Polonsky Michael Jay - - 2012
BACKGROUND: The Theory of Planned Behavior (TPB) has been extensively used to examine donation intentions in the general community. This research seeks to examine whether TPB applies to one culturally and linguistically diverse (CALD) community in Australia and also incorporates blood donation knowledge as an antecedent in the model, given ...
Liu Shihui - - 2012
The endothelialization of the metal surface of vascular stents came into focus as a new method for improving the biocompatibility of intravascular stents. This article has its focus on building a biofunctional layer on the activated titanium surface with anti-CD34 antibody, vascular endothelial growth factor (VEGF), and heparin by a ...
Zhang H - - 2012
The establishment of equine pregnancy is a unique and long process during which a series of physical and possibly biochemical interactions are required between the conceptus and uterus. In this study, we investigated the expression pattern of inhibin/activin subunits in the uterus during early pregnancy. The uteri from four adult ...
Ishida Naoki - - 2012
A rhodium catalyst induced ring opening of benzocyclobutenols with selective cleavage of the C(sp2)-C(sp3) bond adjacent to the hydroxyl group. The site-selectivity markedly contrasted with that of their thermal ring-opening reaction. The rhodium-catalyzed ring opening led to the development of a new alkyne insertion reaction construct-ing a dihydronaphthalene framework.
Vedantam A - - 2012
Study design:Case report.Objective:To demonstrate the utility of diffusion tensor imaging (DTI) and tractography in two patients with Brown-Sequard syndrome after penetrating cervical cord injury.Setting:Milwaukee, WI, USA.Methods:Two patients, who presented with features of Brown-Sequard syndrome after sustaining stab wounds to the neck, underwent DTI and tractography of the cervical cord within ...
Lesch Bluma J - - 2012
The germ line represents a continuous cellular link between generations and between species, but the germ cells themselves develop in a specialized, organism-specific context. The model organisms Caenorhabditis elegans, Drosophila melanogaster and the mouse display striking similarities, as well as major differences, in the means by which they control germ ...
Gao Shigang - - 2012
Curvularia lunata is an important pathogen causing Curvularia leaf spot in maize. Significant pathogenic variation has been found in Curvularia lunata. To better understand the mechanism of this phenomenon, we consecutively put the selective pressures of resistant maize population on Curvularia lunata strain WS18 (low virulence) artificially. As a result, ...
Díaz Franco - - 2012
BACKGROUND: Surfactant deficiency is the pivotal abnormality in Neonatal and Acute Respiratory Distress Syndrome. Surfactant deactivation can produce hypoxemia, loss of lung compliance, and pulmonary edema, but its circulatory consequences are less understood. OBJECTIVE: To describe the sequential hemodynamic changes and pulmonary edema formation after surfactant deactivation in piglets. METHODS: ...
Gumina S - - 2012
Abstract Objective. Arthroscopic rotator cuff repair generally provides satisfactory results, in terms of decreasing shoulder pain and resulting in improvement in range of motion. Unfortunately, imaging studies demonstrate that after surgical repair re-rupture rate is potentially high. Literature data indicate that each of the components present in a supplement commercialized ...
Priye Aashish - - 2012
There is a need for innovative educational experiences that unify and reinforce fundamental principles at the interface between the physical, chemical, and life sciences. These experiences empower and excite students by helping them recognize how interdisciplinary knowledge can be applied to develop new products and technologies that benefit society. Microfluidics ...
Vasko F T - - 2012
Low-energy electronic states in heterostructures formed by ultranarrow layers (single or several monolayers in thickness) are studied theoretically. The host material is described within the effective mass approximation and the effect of ultranarrow layers is taken into account within the framework of the transfer matrix approach. Using the current conservation ...
Li Wei - - 2012
Surface precipitation of metals such as nickel (Ni), zinc (Zn), and cobalt (Co) as layered double hydroxide (LDH) phases is an important pathway for toxic metal sequestration and decontamination in soil environments. To better understand their formation, here we systematically examined the presence of Al and the role of mineral ...
Acevedo J P - - 2012
AIMS: Cloning, expression and characterization of a new cold-adapted protease with potential biotechnological application, isolated from Antarctic bacteria. METHOD AND RESULTS: A subtilisin-like gene was isolated from several Antarctic bacterial genus using CODPEHOP-designed primers and a genome walking method. This gene encodes a precursor protein which undergoes an autocatalytic cleavage ...
Kim Kwan - - 2012
Many drugs are charged molecules and are weak bases or acids having counterions. Their binding to biological surfaces is generally difficult to assess by vibrational spectroscopy. In this work, we demonstrated the potential of surface-enhanced Raman scattering (SERS) conducted using a polyethylenimine (PEI)-capped Ag nanoparticle film for the quantification of ...
Pan Shiguang - - 2012
We here disclosed that the first example of direct C-H bond alkylation of "C2 position" of indole in the cationic iridium-catalyzed reaction with various alkenes. The choice of protecting group (acetyl or benzoyl group) of nitrogen-atom and ligand on Ir (BINAP derivatives or SDP) control the linear/branched selectivity. As for ...
Ducarme Guillaume - - 2012
Abstract Objective: To analyze short-term neonatal outcomes in pregnancies after bariatric surgery according to procedure, to the body mass index (BMI) at the beginning of the pregnancy and to the interval from surgery to conception, using a retrospective multicentric cohort study in three French tertiary perinatal care and bariatric centers. ...
Krumbholz Markus - - 2012
B cells and antibodies account for the most prominent immunodiagnostic feature in patients with multiple sclerosis (MS), namely oligoclonal bands. Furthermore, evidence is accumulating that B cells and antibodies contribute to MS pathogenesis in at least a subset of patients. The CNS provides a B-cell-fostering environment that includes B-cell trophic ...
Ryu Jiwon - - 2012
Robot-assisted minimally invasive surgery is effective for operations in limited space. Enhancing safety based on automatic tracking of surgical instrument position to prevent inadvertent harmful events such as tissue perforation or instrument collisions could be a meaningful augmentation to current robotic surgical systems. A vision-based instrument tracking scheme as a ...
O'Tuathaigh Colm M P - - 2012
Student-selected components (SSCs) encourage the following within the undergraduate medical curriculum: greater exploration of core curriculum topics; exploration of non-core subjects/experiences; research and self-directed learning; and personal and professional development opportunities. This study examined the motivational factors which influence SSC choice to assess (a) SSC selection patterns across each year ...
Chang Ching-Chih - - 2012
Hepatopulmonary syndrome (HPS) is characterized by oxygen desaturation in patients with chronic liver disease. The initiation of HPS comes from abnormal pulmonary vasodilatation and/or angiogenesis. In this study, we evaluated the anti-angiogenesis therapy using sorafenib in experimental HPS animals. HPS was induced by common bile duct ligation (CBDL) in rats. ...
Walker Mark S - - 2012
Abstract Objective: In this retrospective observational study, we describe treatment patterns and longitudinal health related quality of life (HRQOL) among metastatic breast cancer patients with bone metastasis from 9 community oncology clinics. Methods: For description of treatment patterns, patients were classified as treated if they started zoledronic acid within 60 ...
Ford Katy L - - 2012
OBJECTIVE: This study examined variation by age in satisfaction with and perceived benefit from mental health services (MHS). METHODS: Drawn from the nationally representative Collaborative Psychiatric Epidemiology Surveys (2001-2003), the current sample included 1286 adults from age 18 to 87 years who had at least one DSM-IV diagnosis and had used ...
Rahane Amol Babanrao - - 2012
The optical properties of the (Ga(2)O(3))(n) clusters with n=1-10 have been studied within the framework of time dependent density functional theory. The gallium oxide cluster geometries showed evolution from planer configuration (C(2v)) for Ga(2)O(3) to layered globular configuration (C(s)) for Ga(2)O(3))(10) via corundum configuration D(3d)) for (Ga(2)O(3))(4). For n ≤ ...
Saeed Diyar - - 2012
The aim of this study was to evaluate the safety and performance of the Arrow CorAide left ventricular assist system (LVAS) (Arrow International, Reading, PA, USA), a continuous-flow left ventricular assist device, as bridge to transplantation or recovery as well as destination therapy in patients with New York Heart Association ...
Haris Mohammad - - 2012
Glutamate (Glu) is a major excitatory neurotransmitter in the brain and has been shown to decrease in the early stages of Alzheimer's disease (AD). Using a glutamate chemical (amine) exchange saturation transfer (GluCEST) method, we imaged the change in [Glu] in the APP-PS1 transgenic mouse model of AD at high ...
Loughran Jonathan - - 2012
An investigation into the effect of clinical ultrasound exposure on adherent microbubbles is described. A flow phantom was constructed in which targeted microbubbles were attached using biotin-streptavidin linkages. Microbubbles were insonated by broadband imaging pulses (centred at 2.25 MHz) over a range of pressures (peak negative pressure (PNP) = 60-375 kPa). ...
Gião Maria S - - 2012
AIMS: To calculate the shear stress needed to remove sessile Listeria monocytogenes cells from stainless steel (SS) and polytetrafluoroethylene (PTFE) surfaces. METHODS AND RESULTS: L. monocytogenes biofilms were formed on SS and PTFE surfaces. Shear stress was calculated using a radial flow chamber device and cells quantified by staining with ...
Dooley-Hash Suzanne - - 2012
OBJECTIVE: This study describes patterns of emergency department (ED) utilization by patients who screen positive for eating disorders. METHOD: ED patients aged 14-20 years (n = 1,920) completed a computerized questionnaire. The analyses compared the rates of ED use between patients who screened positive for an eating disorder and those ...
Foti Cuzzola V - - 2012
Multiple sclerosis (MS) is an inflammatory and demyelinating disease of central nervous system comprising several subtypes. Pharmacological treatment involves only few drugs. Among these, interferon beta (IFN-β) and glatiramer acetate were the most used. Although evidence supports the efficacy of these agents in treating MS symptoms, actual studies allowed to ...
Mungalpara Jignesh - - 2012
In the absence of an experimentally determined binding mode for the cyclopentapeptide CXCR4 antagonists, we have rationally designed conformationally constrained analogs to further probe the small peptide binding pocket of CXCR4. Two different rigidification strategies were employed, both resulting in highly potent ligands (compounds 9 and 13). The information provided ...
Zhang Ying - - 2012
OBJECTIVE: The purpose of our report is to evaluate the use of color Doppler echocardiography (CDE) with four chamber view (4CV), scanning around left atrium, and four-dimensional echocardiography with B-flow imaging and spatiotemporal image correlation (4D BF-STIC) in detecting fetal pulmonary veins at 17 to 40 weeks' gestation. METHODS: This was ...
Feldkirchner Sarah - - 2012
Myofibrillar myopathies (MFM) are histopathologically characterized by desmin-positive protein aggregates and myofibrillar degeneration. While about half of all MFM are caused by mutations in genes encoding sarcomeric and extra-sarcomeric proteins (desmin, filamin C, plectin, VCP, FHL1, ZASP, myotilin, αB-crystallin, and BAG3), the other half of these diseases is due to ...
Lu Hsiao-Chi - - 2012
Photoluminescence (PL) spectra of natural diamond powders of type IaAB at 300 and 13 K were excited with synchrotron radiation in the wavelength range 150-260 nm. The spectral features observed in the excitation spectra at 13 K show four vibrational progressions -- A, B, B' and N3 related to nitrogen ...
Zhang Lianbin - - 2012
In this study, three-dimensional (3D) graphene assemblies are prepared from graphene oxide (GO) by a facile in situ reduction-assembly method, using a novel, low-cost, and environment-friendly reducing medium which is a combination of oxalic acid (OA) and sodium iodide (NaI). It is demonstrated that the combination of a reducing acid, ...
Audisio Riccardo A - - 2012
Colorectal cancer (CRC) largely affects older individuals; almost half of cases occur in patients >75 years old. The incidence increases with advancing age, doubling every 7 years in patients aged ≥50 years. The medical and societal burdens of CRC will probably worsen over the coming decades as the number of ...
Copie-Bergman Christiane - - 2012
The International Extranodal Lymphoma Study Group (IELSG) promoted this study to determine the inter-observer agreement in the application of the Groupe d' Etude des Lymphomes de l' Adulte (GELA) histological scoring system for evaluating residual disease in post-treatment gastric biopsies of patients with gastric Mucosa-Associated Lymphoid Tissue (MALT) lymphoma (GML). ...
Hansen Richard - - 2012
OBJECTIVES:The gastrointestinal microbiota is considered important in inflammatory bowel disease (IBD) pathogenesis. Discoveries from established disease cohorts report reduced bacterial diversity, changes in bacterial composition, and a protective role for Faecalibacterium prausnitzii in Crohn's disease (CD). The majority of studies to date are however potentially confounded by the effect of ...
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