Search Results
Results 201 - 250 of 2040
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Huang L - - 2012
Objectives:To quantify spinal cord perfusion by using contrast-enhanced ultrasound (CEUS) in a porcine model with acute spinal cord injury.Methods:Microcirculatory changes of acute spinal cord injury were shown by CEUS in a porcine model with spinal cord contusion at three selected time points, coupling with conventional ultrasound (US) and Color Doppler ...
Champagne Antoine - - 2012
Madagascar periwinkle (Catharanthus roseus) is the major source of terpenoid indole alkaloids, such as vinblastine or vincristine, used as natural drugs against various cancers. In this study, we have extensively analyzed the proteome of cultured C. roseus cells. Comparison of the proteomes of two independent cell lines with different terpenoid ...
Lam David Cl - - 2012
We are witnessing a rapid transformation of clinical practice as more of what we do in medicine becomes informed by an increasingly accelerated application of scientific knowledge derived from basic science research. This process represents the essence of what is now termed clinical translational research, which entails the infusion of ...
Barratt Monica J - - 2012
INTRODUCTION AND AIMS: To assess the demographic profile, use patterns, market characteristics, reasons for first use and self-reported harms associated with use of synthetic cannabinoids in Australia. DESIGN AND METHODS: An online questionnaire was administered to a purposive sample of 316 Australian synthetic cannabinoid users [96% cannabis users, 77% male, ...
Claramunt Rafael - - 2012
The mechanical behavior of calf pericardium, a biomaterial utilized in the manufacture of cardiac bioprostheses, in response to a short tensile cyclic test has been evaluated. The trial involved 120 samples cut longitudinally or transversely, subjected to 10 cycles until a stress of between 1 and 3 MPa was reached. Tests ...
Koh Andy - - 2012
A common question of interest to researchers in psychology is the equivalence of two or more groups. Failure to reject the null hypothesis of traditional hypothesis tests such as the ANOVA F-test (i.e., H(0) : μ(1)  = … = μ(k) ) does not imply the equivalence of the population means. Researchers interested ...
Yang Zhi - - 2012
Using density functional theory and the non-equilibrium Green's function technique, we performed theoretical investigations on the magnetic and quantum transport properties of benzene-vanadium-borazine mixed organic/inorganic ligand sandwich clusters. The calculated results show that these finite sandwich clusters coupled to Ni electrodes exhibit novel quantum transport properties such as half-metallicity, negative ...
Hua Renyi - - 2012
PROBLEM: Human labour is an inflammatory process with a heavy infiltration of immune cells into the myometrium and cervix induced by local chemokine production. Myometrial cells also express chemokine receptors, but there is little information about their behaviour or function during pregnancy and labour. METHOD OF STUDY: We studied the ...
Elliott Timothy G - - 2012
BACKGROUND/OBJECTIVES: Dermatologists commonly perform surgical procedures, including Mohs micrographic surgery, in an outpatient, office-based setting. Although this may be widely perceived to be safe and effective, formal data on the practice are limited. The aim of this study was to examine the range of surgical procedures and associated complications in ...
Sattar Akm A - - 2012
Adiponectin (Adp), an adipocyte secreted hormone, exerts its effect via its specific receptors, adiponectin receptors (AdipoR1 and AdipoR2), in insulin sensitive cells in muscle, liver, and adipose tissues and plays an important role in lipid and glucose metabolism. The aim of the current study was to investigate the effect of ...
Digirolamo Douglas J - - 2012
Surprising new discoveries in the field of skeletal biology show that bone cells produce endocrine hormones that regulate phosphate and glucose homeostasis. In this Review, we examine the features of these new endocrine pathways and discuss their physiological importance in the context of our current understanding of energy metabolism and ...
Zhu Hui - - 2012
Poly(o-phenylenediamine) (POPD)-derived functional carbon materials with excellent capacitive performance are successfully synthesized by means of an integrated one-step process, in which FeCl(3) not only oxidizes the polymerization of the organic monomers but also activates the carbonization. Furthermore, extensive research has proved that this strategy to discover novel carbons is useful ...
Lyseng-Williamson Katherine A - - 2012
Melatonin prolonged release (PR) 2 mg is approved for the treatment of primary insomnia characterized by poor sleep quality in patients aged ≥55 years in the EU and elsewhere. Patients may receive treatment with melatonin PR for up to 13 weeks. Production of endogenous nocturnal melatonin, which helps regulate circadian rhythm, may be ...
- - 2012
The following articles are being highlighted as part of Circulation's Topic Review series. This series will summarize the most important manuscripts, as selected by the editors, published in Circulation and the Circulation subspecialty journals. The studies included in this article represent the most read manuscripts published on the topic of ...
Cui C - - 2012
We report a study of the atomic structure of the threefold icosahedral (i-)Ag-In-Yb quasicrystal surface using scanning tunneling microscopy (STM) and low energy electron diffraction (LEED). The LEED confirms that the surface exhibits quasicrystalline long-range order with the threefold symmetry expected from the bulk. The STM reveals large atomically flat ...
Andrzejczak Ewa - - 2012
BACKGROUD: The present study assessed the degree to which undergoing a mastectomy without reconstructive surgery negatively impacts the patient's psychological state. We focus on body image and self-esteem as well as the influence of mastectomy on patient sex lives and partnership relations. METHODS: The participants were 60 women, either married ...
Sivertsen Børge - - 2012
Several studies have indicated a high degree of overlap between insomnia and obstructive sleep apnoea, but little is known regarding how the overlap may affect adverse outcomes associated with each of the disorders. The aim of the current study was to examine the separate and combined effects of symptoms of ...
Li Yi-Chen - - 2012
Context: For 2000 years, traditional Chinese medicine has been used as a remedy for general health improvement, including the fight against aging. Pearl powder has recently been used as a health food that has antioxidant, antiaging, antiradioactive, and tonic activities for cells; it is also applied to cure aphthous ulcer, ...
Rescigno Pasquale - - 2012
Prostate Cancer is the most commonly diagnosed malignancy and the second leading cause of cancer-related death in men in the Western World. Docetaxel-based chemotherapy has been the mainstay of treatment until a few years ago for metastatic castration resistant prostatic cancer (mCRPC). Recently, a broad range of therapeutic options has ...
Jacobson George Lloyd - - 2012
Between 45,000 cal y BP and the beginning of the Holocene, the accumulation rate for Hg in sediments of Lake Tulane, Florida USA ranged from ≈2 to 10 µg m-2 y-1, compared with 53 µg Hg m-2 y-1 in the 1985-1990 period of anthropogenic input. The locality experienced regional draw-down ...
Szekeres A - - 2012
Fumonisin B1 (FB1) is a highly toxic mycotoxin produced by fungal strains belonging to the Fusarium genus, which can be found mainly in maize products, and is gaining interest in food safety. To produce large amounts of pure FB1, a novel purifying method was developed by using centrifugal partition chromatography, ...
Samuel Edward R - - 2012
Cytomegalovirus (CMV) infections post-haematopoietic stem cell transplantation (HSCT) can be effectively controlled through the adoptive transfer of donor-derived CMV-specific T cells (CMV-T). Current strategies involve a second leukapheresis collection from the original donor to manufacture CMV-T, which is often not possible in the unrelated donor setting. To overcome these limitations ...
Cédola C V - - 2012
Among the herbivorous arthropods that feed on strawberry, the most important are the two-spotted spider mite (TSSM), Tetranychus urticae Koch, and several species of aphids. Mites and aphids belong to different guilds that coexist in the field and feed on the undersides of strawberry leaflets. However, the occurrence of large ...
Striegel Ruth H - - 2012
OBJECTIVE: To examine productivity impairment in individuals with obesity and/or binge eating. METHOD: Based on current weight and eating behavior, 117,272 employees who had completed a health risk appraisal and psychosocial functioning questionnaire were classified into one of four groups. Gender-stratified analyses compared groups on four measures: absenteeism, presenteeism, total ...
Klotsche Jens - - 2012
Models that predict disease incidence or disease recurrence are attractive for clinicians as well as for patients. The usefulness of a risk prediction model is linked to the two questions whether the observed outcome is confirmed by the prediction and whether the risk prediction is accurate in predicting the future ...
Karppi Jouni - - 2012
Intake of fruits and vegetables and levels of serum carotenoids have been associated with decreased risk of stroke, but the results have been inconsistent. The aim of the present study was to examine whether serum concentrations of major carotenoids, α-tocopherol and retinol, are related to any stroke and ischemic stroke ...
Morawski J - - 2012
Abstract Objective. Chronic pancreatitis (CP) is the most common cause of pancreatic exocrine insufficiency (PEI). Management of PEI due to CP is achieved through lifelong treatment with pancreatic enzyme replacement therapy (PERT). To our knowledge no cost-effectiveness analysis on the benefit of PERT in CP patients with PEI has been ...
Golay Vishal - - 2012
AIM: Optimal time of observation following percutaneous biopsy has not been clearly established. Outpatient biopsy protocol was established in our centre for low risk patients and we assessed its efficacy and safety. METHODS: Patients fulfilling the low risk profile underwent a real time ultrasound-guided percutaneous native kidney biopsy. They were ...
Manning Victoria - - 2012
INTRODUCTION AND AIMS: Evidence of treatment effectiveness for alcohol use disorders (AUD) have emerged predominantly from Western studies, using highly controlled trials that may not reflect real-world settings. This paper examines treatment outcome and its predictors among Asian problem drinkers participating in a treatment outcome monitoring program at an addiction ...
Ulusoy Sukru - - 2012
Hemodialysis (HD) adequacy requires monitoring in line with standards and at appropriate intervals. However, the use of inappropriate or incorrectly applied techniques in the determination of HD adequacy can lead to highly unfortunate results. This study was intended to identify the path to a solution by determining how far HD ...
Guo Xia - - 2012
A new copolymer PIDTDTQx based on indacenodithiophene and quinoxaline is synthesized and characterized. The correlation between the D/A ratio, mobility, and photovoltaic properties, as well as morphology of the D/A blend based on a PIDTDTQx:PC(70) BM system is investigated. The power conversion efficiency of the polymer solar cells based on ...
Chandio Zaheer A - - 2012
The concentration of cadmium and zinc in vegetables was determined by using an online flame atomic absorption spectrophotometer after simultaneous pre-concentration based on the complexation of Cd and Zn with 1,5-diphenylthiocarbazone immobilised on naphthalene. The effect of pH, sample flow rate and amount of 1,5-diphenylthiocarbazone on adsorption was investigated. After ...
Wetterling Friedrich - - 2012
A double-tuned (23)Na/(1)H resonator system was developed to record multinuclear MR image data during and after transient cerebral ischemia. (1)H-diffusion-, (1)H perfusion, (1)H T(2)-, (1)H arterial blood flow- and (23)Na spin density-weighted images were then acquired at three time points in a rodent stroke model: (I) during 90 min artery occlusion, ...
Schnabel Alexander - - 2012
BACKGROUND: Aim of the current meta-analysis was to assess the effects of intraoperative dexmedetomidine on postoperative pain, analgesic consumption, and adverse events in comparison with placebo or opioids in children undergoing surgery. METHODS: This meta-analysis was performed according to the recommendations of the PRISMA statement and the Cochrane collaboration. For ...
Egan Sarah J - - 2012
Background: Clinical perfectionism is a transdiagnostic process that has been found to maintain eating disorders, anxiety disorders and depression. Cognitive behavioural models explaining the maintenance of clinical perfectionism emphasize the contribution of dichotomous thinking and resetting standards higher following both success and failure in meeting their goals. There has been ...
Kim Jin-Sun - - 2012
Aims and objectives.  The aim of this study was to test the initial psychometric properties of the Emotional Reactions Instrument-English with hospitalised American children, ages 7-12 years, in the USA. Background.  Children's negative emotional responses have been a subject of concern for paediatric clinicians and researchers, especially because negative emotional responses ...
Timoshkin Alexey Y - - 2012
Lewis acidity trends of aluminum and gallium halides have been considered on the basis of joint X-ray and density functional theory studies. Structures of complexes of heavier group 13 element trihalides MX(3) (M = Al, Ga; X = Cl, Br, I) with monodentate nitrogen-containing donors Py, pip, and NEt(3) as ...
Farrow Sheelagh - - 2012
Abstract Objective: The requirement for formal Continuing Medical Education (CME) is growing in Europe with a concomitant focus on quality and independence of medical educational programmes together with a need for measurable effects on patient outcomes. However, during this rapid evolution, it has become clear that there are misunderstandings and ...
Frankel H L - - 2012
This Ludwig Guttmann Lecture was presented at the 2012 meeting of the International Spinal Cord Society in London. It describes the contribution of Stoke Mandeville Hospital to the field of spinal cord injuries. Dr Ludwig Guttmann started the Spinal Unit at Stoke Mandeville Hospital in 1944 and introduced a novel, ...
Mas Salvador - - 2012
Chenopodiaceae pollens such as those from Salsola kali and Chenopodium album are important causes of allergy in Mediterranean areas because of the progress of desertification in European countries. Among the different allergenic protein families, profilins constitute a group of panallergens involved in polysensitization and pollen-food allergy syndrome. Two-dimensional electrophoresis analysis ...
Chen Zhuo - - 2012
A 29-year-old renal transplant patient taking mycophenolate mofetil 1 g b.i.d., cyclosporine 100 mg b.i.d. and prednisone 10 mg q.d. presented with white paint, dot-like incrustations on the skin of his right scrotum. A 10% potassium hydroxide preparation of scrapings from the lesions showed septate hyphae and Microsporum gypseum was cultured. Topical bifonazole ...
Kolář Michal - - 2012
BACKGROUND INFORMATION: Considering an analogy between wound healing and tumor progression, we studied chemo- and cytokine expression in normal fibroblasts by coculture and in situ, completed by transcriptome analyses. RESULTS: Whole-genome transcriptome profiling revealed strong upregulation for the interleukins-6 and -8 (IL-6, IL-8) and the chemokine CXCL-1 in in vitro ...
Berland Astrid - - 2012
This study explored patient safety and falls, based on the experiences of home care nurses. Four focus group interviews were conducted with 20 home care nurses. The data were analyzed by content analysis. This study identified the following four themes: (i) patient safety was not viewed as primary prevention; (ii) ...
Sainthillier Jean-Marie - - 2012
BACKGROUND: Post-menopausal skin aging has intrinsic as well as extrinsic origins, and this process induces important disparities of appearance and feeling within an age range. OBJECTIVE: The objective of this study was to identify 3 grades of maturity of the facial skin of menopausal women. MATERIAL AND METHOD: One hundred ...
Jacobs M M - - 2012
Opioid drugs are highly addictive and their abuse has a strong genetic load. Dopamine-glutamate interactions are hypothesized to be important for regulating neural systems central for addiction vulnerability. Balanced dopamine-glutamate interaction is mediated through several functional associations, including a physical link between discs, large homolog 4 (Drosophila) (DLG4, PSD-95) and ...
Charles P H - - 2012
The purpose of this study was to investigate the effect of very small air gaps (less than 1 mm) on the dosimetry of small photon fields used for stereotactic treatments. Measurements were performed with optically stimulated luminescent dosimeters (OSLDs) for 6 MV photons on a Varian 21iX linear accelerator with a ...
Yiannakopoulou E Ch - - 2012
The clinical impact of pharmacogenomics remains a hot topic of current research efforts. Although pharmacogenomics of phase I metabolizing enzymes seems to have been well studied, knowledge on the clinical impact of genetic variability of phase II metabolizing enzymes and drug transporters is more limited. This paper reviews data on ...
Woodling Marie - - 2012
Abstract There have been recent indications that the primacy of AIDS among global health issues may be under threat. In this article we examine one response to have emerged from the AIDS policy community as a result of this perceived threat: the 'AIDS plus Millennium Development Goals (MDGs)' approach, which ...
Schagdarsurengin Undraga - - 2012
An understanding of the epigenetic mechanisms involved in sperm production and their impact on the differentiating embryo is essential if we are to optimize fertilization and assisted reproduction techniques in the future. Male germ cells are unique in terms of size, robustness, and chromatin structure, which is highly condensed owing ...
Ochodnicky Peter - - 2012
Increased voiding frequency and urgency are among the most prevalent storage lower urinary tract symptoms (LUTS), often diagnosed as part of overactive bladder syndrome (OAB). It has been suggested that these symptoms are caused by excessive sensory activation of the neural micturition circuit. It seems likely that sensory pathway remodelling ...
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