Search Results
Results 201 - 250 of 2040
< 1 2 3 4 5 6 7 8 9 10 >
Graziano P A - - 2012
Objectives:To investigate the role of toddlers' self-regulation skills and temperament in predicting weight outcomes in preadolescence.Methods:Participants for this study included 195 children (114 girls) obtained from three different cohorts participating in a larger ongoing longitudinal study. At 2 years of age, participants participated in several laboratory tasks designed to assess ...
Chen Zhuo - - 2012
A 29-year-old renal transplant patient taking mycophenolate mofetil 1 g b.i.d., cyclosporine 100 mg b.i.d. and prednisone 10 mg q.d. presented with white paint, dot-like incrustations on the skin of his right scrotum. A 10% potassium hydroxide preparation of scrapings from the lesions showed septate hyphae and Microsporum gypseum was cultured. Topical bifonazole ...
Kolář Michal - - 2012
BACKGROUND INFORMATION: Considering an analogy between wound healing and tumor progression, we studied chemo- and cytokine expression in normal fibroblasts by coculture and in situ, completed by transcriptome analyses. RESULTS: Whole-genome transcriptome profiling revealed strong upregulation for the interleukins-6 and -8 (IL-6, IL-8) and the chemokine CXCL-1 in in vitro ...
Berland Astrid - - 2012
This study explored patient safety and falls, based on the experiences of home care nurses. Four focus group interviews were conducted with 20 home care nurses. The data were analyzed by content analysis. This study identified the following four themes: (i) patient safety was not viewed as primary prevention; (ii) ...
Badr Hoda H Oncological Sciences, Mount Sinai School of Medicine, New York, NY 10029, USA. - - 2013
Quality of life (QOL) is a multidimensional construct that includes physical, psychological, and relationship well-being. We conducted a systematic review and meta-analysis of randomized controlled studies published between 1980 and 2012 of interventions conducted with both cancer patients and their partners that were aimed at improving QOL. Using bibliographic software ...
Baschant Ulrike - - 2012
Glucocorticoids have potent anti-inflammatory effects and have been used to treat patients with rheumatoid arthritis for more than 60 years. However, severe adverse effects of glucocorticoid treatment, including loss of bone mass and increased risk of fractures, are common. Data from studies of glucocorticoid-mediated gene regulation, which utilized conditional knockout ...
Karppi Jouni - - 2012
Intake of fruits and vegetables and levels of serum carotenoids have been associated with decreased risk of stroke, but the results have been inconsistent. The aim of the present study was to examine whether serum concentrations of major carotenoids, α-tocopherol and retinol, are related to any stroke and ischemic stroke ...
Morawski J - - 2012
Abstract Objective. Chronic pancreatitis (CP) is the most common cause of pancreatic exocrine insufficiency (PEI). Management of PEI due to CP is achieved through lifelong treatment with pancreatic enzyme replacement therapy (PERT). To our knowledge no cost-effectiveness analysis on the benefit of PERT in CP patients with PEI has been ...
Golay Vishal - - 2012
AIM: Optimal time of observation following percutaneous biopsy has not been clearly established. Outpatient biopsy protocol was established in our centre for low risk patients and we assessed its efficacy and safety. METHODS: Patients fulfilling the low risk profile underwent a real time ultrasound-guided percutaneous native kidney biopsy. They were ...
Flint Jonathan J The Wellcome Trust Centre for Human Genetics, Roosevelt Drive, Oxford OX3 7BN, - - 2012
Genome-wide association studies (GWASs) have transformed the field of human genetics and have led to the discovery of hundreds of genes that are implicated in human disease. The technological advances that drove this revolution are now poised to transform genetic studies in model organisms, including mice. However, the design of ...
Xu Fang - - 2012
This manuscript first describes a simple synthesis of tungsten oxide (WO(x)) nanorods from templated W foil using a chemical vapour deposition (CVD) technique at 600-750 °C, then presents the formation of tungsten oxynitride (WO(x)N(y)) nanorods via nitridation at 650 °C for different reaction times. The W foil, blade engraved, acid ...
Arpan Ishu I Department of Physical Therapy, University of Florida, Gainesville, FL, - - 2013
Skeletal muscles of children with Duchenne muscular dystrophy (DMD) show enhanced susceptibility to damage and progressive lipid infiltration, which contribute to an increase in the MR proton transverse relaxation time (T₂). Therefore, the examination of T₂ changes in individual muscles may be useful for the monitoring of disease progression in ...
Pang Maolin - - 2012
Structures of Gold: A simple transformative method for nanoscale sculpturing has been developed. Five different types of complex nanocomposites of cuprite and gold have been formed by using this self-etching approach.
Chandio Zaheer A - - 2012
The concentration of cadmium and zinc in vegetables was determined by using an online flame atomic absorption spectrophotometer after simultaneous pre-concentration based on the complexation of Cd and Zn with 1,5-diphenylthiocarbazone immobilised on naphthalene. The effect of pH, sample flow rate and amount of 1,5-diphenylthiocarbazone on adsorption was investigated. After ...
Wetterling Friedrich - - 2012
A double-tuned (23)Na/(1)H resonator system was developed to record multinuclear MR image data during and after transient cerebral ischemia. (1)H-diffusion-, (1)H perfusion, (1)H T(2)-, (1)H arterial blood flow- and (23)Na spin density-weighted images were then acquired at three time points in a rodent stroke model: (I) during 90 min artery occlusion, ...
Schnabel Alexander - - 2012
BACKGROUND: Aim of the current meta-analysis was to assess the effects of intraoperative dexmedetomidine on postoperative pain, analgesic consumption, and adverse events in comparison with placebo or opioids in children undergoing surgery. METHODS: This meta-analysis was performed according to the recommendations of the PRISMA statement and the Cochrane collaboration. For ...
Egan Sarah J - - 2012
Background: Clinical perfectionism is a transdiagnostic process that has been found to maintain eating disorders, anxiety disorders and depression. Cognitive behavioural models explaining the maintenance of clinical perfectionism emphasize the contribution of dichotomous thinking and resetting standards higher following both success and failure in meeting their goals. There has been ...
Cédola C V - - 2012
Among the herbivorous arthropods that feed on strawberry, the most important are the two-spotted spider mite (TSSM), Tetranychus urticae Koch, and several species of aphids. Mites and aphids belong to different guilds that coexist in the field and feed on the undersides of strawberry leaflets. However, the occurrence of large ...
Striegel Ruth H - - 2012
OBJECTIVE: To examine productivity impairment in individuals with obesity and/or binge eating. METHOD: Based on current weight and eating behavior, 117,272 employees who had completed a health risk appraisal and psychosocial functioning questionnaire were classified into one of four groups. Gender-stratified analyses compared groups on four measures: absenteeism, presenteeism, total ...
Klotsche Jens - - 2012
Models that predict disease incidence or disease recurrence are attractive for clinicians as well as for patients. The usefulness of a risk prediction model is linked to the two questions whether the observed outcome is confirmed by the prediction and whether the risk prediction is accurate in predicting the future ...
Sandborn William J WJ University of California San Diego, La Jolla, CA 92093-0956, USA. - - 2013
Andrographis paniculata has in vitro inhibitory activity against TNF-α, IL-1β and NF-κB. A pilot study of A. paniculata extract (HMPL-004) suggested similar efficacy to mesalamine for ulcerative colitis. A randomized, double-blind, placebo-controlled trial evaluated the efficacy of A. paniculata extract (HMPL-004) in 224 adults with mild-to-moderate ulcerative colitis. Patients were ...
Kritzinger E C - - 2012
A novel, robust and fast ultra-high performance liquid chromatography-MS method has been developed for the simultaneous quantification of reduced glutathione (GSH) and oxidised glutathione (GSSG) in grape juice, wine and model wine solution. Sample preparation is minimal and does not require derivatisation. The method has very good performance in terms ...
Furtado Paulo Sampaio - - 2012
Disorders of sex development (DSDs) are estimated to be prevalent in 0.1-2% of the global population, although these figures are unlikely to adequately represent non-white patients as they are largely based on studies performed in Europe and the USA. Possible causes of DSDs include disruptions to gene expression and regulation-processes ...
Xu Xinxiu - - 2013
Environmental stress-mediated adaptation plays essential roles in the evolution of life. Cellular adaptation mechanisms usually involve the regulation of chromatin structure, transcription, mRNA stability and translation, which eventually lead to efficient changes in gene expression. Global epigenetic change is also involved in the reprogramming of somatic cells into induced pluripotent ...
Concina Isabella - - 2012
Growth kinetics of CdSe nanocrystals generated inside three selected polymers (polyvinylpyrrolidone - PVP, polyethyleneglycol - PEG and polyvinylalcohol - PVA) are demonstrated to follow a self-catalytic path, with growth rates depending on the nature of the polymer, i.e. on the capability to activate the cadmium species present in the solution ...
Polonsky Michael Jay - - 2012
BACKGROUND: The Theory of Planned Behavior (TPB) has been extensively used to examine donation intentions in the general community. This research seeks to examine whether TPB applies to one culturally and linguistically diverse (CALD) community in Australia and also incorporates blood donation knowledge as an antecedent in the model, given ...
Liu Shihui - - 2012
The endothelialization of the metal surface of vascular stents came into focus as a new method for improving the biocompatibility of intravascular stents. This article has its focus on building a biofunctional layer on the activated titanium surface with anti-CD34 antibody, vascular endothelial growth factor (VEGF), and heparin by a ...
Dalleur Olivia - - 2012
BACKGROUND: Over the last few years, the Screening Tool of Older Person's Prescriptions (STOPP) and Screening Tool to Alert doctors to Right Treatment (START) criteria have been increasingly used to evaluate the prevalence of inappropriate prescribing. However, very few studies have evaluated the link between these criteria and clinical outcomes. ...
Wyatt J E - - 2012
With the beginning of the Human Genome Project, an emerging field of science was brought to the forefront of the pharmaceutical community. Pharmacogenetics facilitates optimization of the current patient-centered care model and pharmacotherapy as a whole. Utilizing these ever-expanding branches of science to nonsteroidal anti-inflammatory drugs (NSAIDs) can provide novel ...
O'Tuathaigh Colm M P - - 2012
Student-selected components (SSCs) encourage the following within the undergraduate medical curriculum: greater exploration of core curriculum topics; exploration of non-core subjects/experiences; research and self-directed learning; and personal and professional development opportunities. This study examined the motivational factors which influence SSC choice to assess (a) SSC selection patterns across each year ...
Chang Ching-Chih - - 2012
Hepatopulmonary syndrome (HPS) is characterized by oxygen desaturation in patients with chronic liver disease. The initiation of HPS comes from abnormal pulmonary vasodilatation and/or angiogenesis. In this study, we evaluated the anti-angiogenesis therapy using sorafenib in experimental HPS animals. HPS was induced by common bile duct ligation (CBDL) in rats. ...
Bat Taha T Hematology Branch, National Heart, Lung, and BloodInstitute, National Institutes of Health, Bethesda, MD 20892, - - 2013
The ability to distinguish increased platelet (PLT) destruction from PLT hypoproduction is important in the care of patients with marrow failure syndromes and patients receiving high-dose chemotherapy. The measurement of immature circulating PLTs based on RNA content using an automated counter is now feasible. This study evaluated the impact of ...
Dmitrienko Alex - - 2012
Much progress has been made over the past decade with the development of novel methods for addressing increasingly more complex multiplicity problems arising in confirmatory Phase III clinical trials. This includes traditional problems with a single source of multiplicity, for example, analysis of multiple endpoints or dose-placebo contrasts. In addition, ...
Clasie Benjamin M - - 2012
The γ-index is used routinely to establish correspondence between two dose distributions. The definition of the γ-index can be written with a single equation but solving this equation at millions of points is computationally expensive, especially in three dimensions. Our goal is to extend the vector-equation method in Bakai et ...
Hailer Yasmin D - - 2012
Previous studies have suggested that Legg-Calvé-Perthes disease (LCPD) is associated with repetitive trauma, coagulation problems and anatomical abnormalities of the blood supply to the femoral head. The hypothesis that repetitive trauma can affect the blood supply of the femoral head, leading to LCPD, is supported by an animal model. For ...
Persson Asha - - 2012
Abstract Serodiscordant primary relationships, in which one partner is HIV-positive and the other is HIV-negative, are increasingly recognised as a key context for the transmission of HIV globally. Yet insights into the dynamics of serodiscordance remain relatively limited. I argue that to understand what makes serodiscordant couples engage in sexual ...
Fluttert Frans Aj - - 2012
AIMS AND OBJECTIVES: The Forensic Early Warning Signs of Aggression Inventory (FESAI) was developed to assist nurses and patients in identifying early warning signs and constructing individual early detection plans (EDP) for the prevention of aggressive incidents. The aims of this research were as follows: First, to study the prevalence ...
Bieberle-Hütter A - - 2012
An integrated system of a microreformer and a carrier allowing for syngas generation from liquefied petroleum gas (LPG) for micro-SOFC application is discussed. The microreformer with an overall size of 12.7 mm × 12.7 mm × 1.9 mm is fabricated with micro-electro-mechanical system (MEMS) technologies. As a catalyst, a special ...
Vignolini Silvia - - 2012
The Mediterranean orchid genus Ophrys is remarkable for its pseudocopulatory pollination mechanism; naïve male pollinators are attracted to the flowers by olfactory, visual and tactile cues. The most striking visual cue is a highly reflective, blue speculum region at the centre of the labellum, which mimics the corresponding female insect ...
Bergamasco M D - - 2012
Candidemia in cancer patients may differ according to the type of cancer. To characterise the epidemiology and outcome of candidemia in cancer patients from Brazilian hospitals, we compared the characteristics of patients with hematologic malignancies (HM) and solid tumours (ST). A retrospective study was performed, based on data collected from ...
Zakai Neil A NA Departments of Medicine and Pathology, University of Vermont, Burlington, Vermont College of Medicine, USA. - - 2013
While anemia is associated with poor functional and mortality outcomes in the elderly, the impact of hemoglobin decline is less studied. We evaluated the determinants and consequences of hemoglobin decline in 3,758 non-anemic participants from the Cardiovascular Health Study, a prospective cohort of community-dwelling elderly ≥65 years old at baseline ...
Stock E - - 2012
A novel concept for on-chip quantum optics using an internal electrically pumped microlaser is presented. The microlaser resonantly excites a quantum dot microcavity system operating in the weak coupling regime of cavity quantum electrodynamics. This work presents the first on-chip application of quantum dot microlasers, and also opens up new ...
Acevedo J P - - 2012
AIMS: Cloning, expression and characterization of a new cold-adapted protease with potential biotechnological application, isolated from Antarctic bacteria. METHOD AND RESULTS: A subtilisin-like gene was isolated from several Antarctic bacterial genus using CODPEHOP-designed primers and a genome walking method. This gene encodes a precursor protein which undergoes an autocatalytic cleavage ...
Kim Kwan - - 2012
Many drugs are charged molecules and are weak bases or acids having counterions. Their binding to biological surfaces is generally difficult to assess by vibrational spectroscopy. In this work, we demonstrated the potential of surface-enhanced Raman scattering (SERS) conducted using a polyethylenimine (PEI)-capped Ag nanoparticle film for the quantification of ...
Pan Shiguang - - 2012
We here disclosed that the first example of direct C-H bond alkylation of "C2 position" of indole in the cationic iridium-catalyzed reaction with various alkenes. The choice of protecting group (acetyl or benzoyl group) of nitrogen-atom and ligand on Ir (BINAP derivatives or SDP) control the linear/branched selectivity. As for ...
Priye Aashish - - 2012
There is a need for innovative educational experiences that unify and reinforce fundamental principles at the interface between the physical, chemical, and life sciences. These experiences empower and excite students by helping them recognize how interdisciplinary knowledge can be applied to develop new products and technologies that benefit society. Microfluidics ...
Vasko F T - - 2012
Low-energy electronic states in heterostructures formed by ultranarrow layers (single or several monolayers in thickness) are studied theoretically. The host material is described within the effective mass approximation and the effect of ultranarrow layers is taken into account within the framework of the transfer matrix approach. Using the current conservation ...
Li Wei - - 2012
Surface precipitation of metals such as nickel (Ni), zinc (Zn), and cobalt (Co) as layered double hydroxide (LDH) phases is an important pathway for toxic metal sequestration and decontamination in soil environments. To better understand their formation, here we systematically examined the presence of Al and the role of mineral ...
Li Yi-Chen - - 2012
Context: For 2000 years, traditional Chinese medicine has been used as a remedy for general health improvement, including the fight against aging. Pearl powder has recently been used as a health food that has antioxidant, antiaging, antiradioactive, and tonic activities for cells; it is also applied to cure aphthous ulcer, ...
Rescigno Pasquale - - 2012
Prostate Cancer is the most commonly diagnosed malignancy and the second leading cause of cancer-related death in men in the Western World. Docetaxel-based chemotherapy has been the mainstay of treatment until a few years ago for metastatic castration resistant prostatic cancer (mCRPC). Recently, a broad range of therapeutic options has ...
< 1 2 3 4 5 6 7 8 9 10 >