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Salamonsen Lois A - - 2012
Failure of the endometrium to achieve receptivity results in infertility, and it is also a rate-limiting step in in vitro fertilization (IVF) success. The microenvironments provided by the endometrium during the receptive phase and that support implantation are highly complex and constantly changing as implantation progresses. Although a number of gene ...
Bazot M - - 2012
AIM: To analyse the morphological magnetic resonance imaging (MRI) features of borderline ovarian tumours (BOT) and to evaluate whether MRI can be used to distinguish serous from mucinous subtypes. MATERIALS AND METHODS: A retrospective study of 72 patients who underwent BOT resection was undertaken. MRI images were reviewed blindly by ...
Tian Ruijuan - - 2013
To determine differential expression of G-protein-coupled receptor 30 (GPR30) in uterine leiomyoma and its matched myometrium. GPR30 expression examined in both tissues and cultured cells. Research laboratories. Women 35 to 50 years old with uterine leiomyomas. Hysterectomy. GPR30 expression profile. Using Western blot and real-time quantitative polymerase chain reaction analyses, ...
Bellantuono Cesario - - 2013
Benzodiazepines (BDZs) safety profiles in pregnancy suggest that the risk of major malformations (MMs) cannot be considered simply as a "class effect". The aim of this paper was to review and update the available literature on the risks of MMs in women exposed to BDZs in the first trimester of ...
Afsar Baris - - 2013
Cognitive impairment, depression, sleep disorders and impaired quality of life are very common in hemodialysis (HD) patients. However, whether there are any seasonal changes of cognitive impairment, depression, sleep disorders and quality of life in HD patients is not known. The laboratory parameters, depressive symptoms, health-related quality of life, sleep ...
Gros Daniel F - - 2013
Obsessive compulsive disorder (OCD) is a severely impairing psychiatric disorder with an estimated 12-month prevalence of 0.39% to 1.20% in community settings. However, there has been little research on the prevalence of OCD in primary care settings and veteran samples. Thus, the present study investigated prevalence, comorbidity, and physical and ...
Simopoulos Eugene F - - 2013
Erectile dysfunction (ED), defined as the inability to achieve or maintain an erection sufficient for satisfactory sexual performance, is the most common sexual problem in men. ED arises when there is disruption of the complex interplay between vascular, neurologic, hormonal and psychologic factors necessary for normal erectile function. It may ...
Hsu Heng-Jung - - 2013
Patients with chronic kidney disease (CKD) who are undergoing maintenance hemodialysis have a higher prevalence of depression than the general population. The underlying cause of this association is unknown, but may be related to accumulation of uremic toxins. Little is known about the association of accumulation of uremic toxins and ...
Ma J - - 2012
The use of a percutaneous compression plate (PCCP) provides a minimally invasive technique for the fixation of stable intertrochanteric femoral fractures. It has several theoretically potential advantages over the dynamic hip screw (DHS) such as shorten incision and lower incidence of wound infection. PCCP have several advantages than DHS, such ...
Massin P - - 2012
Extended femoral and tibial osteotomies were performed to remove infected cemented hinged knee prostheses in five patients (six knees) with a mean age of 72 years (44-85) and a history of multiple knee surgeries. A tibial osteotomy was used to mobilise the distal quadriceps insertion and to release the tibial ...
Lonjon G - - 2012
Spine surgery is known to have a high risk of surgical site infection (SSI). Multiple studies have looked into the risk factors and incidence of SSI during elective surgery, but only two retrospective studies have specifically evaluated SSI during surgery following spine trauma. This work was based on a prospective ...
Cator Lauren J - - 2012
Malaria parasites have been suggested to alter the behavior of mosquito vectors to increase the likelihood of transmission. Some empirical evidence supports this hypothesis, yet the role of manipulation is ignored in most epidemiological models, and behavioral differences between infected and uninfected females are not considered in the development or ...
Huang Liyi L Department of Infectious Diseases, First Affiliated College & Hospital, Guangxi Medical University, Nanning, China - - 2012
Sodium azide (NaN(3)) is widely employed to quench singlet oxygen during photodynamic therapy (PDT), especially when PDT is used to kill bacteria in suspension. We observed that addition of NaN(3) (100 μM or 10 mM) to gram-positive Staphylococcus aureus and gram-negative Escherichia coli incubated with methylene blue (MB) and illuminated ...
Todman Steven H SH Department of Pediatrics (Cardiology), Indiana University School of Medicine, Indianapolis, Ind, - - 2013
Interrupted aortic arch is a rare congenital anomaly affecting 1.5% of infants with congenital heart disease. Multiple surgical modalities exist to address this defect. We evaluate the long-term outcome of interrupted aortic arch with the left carotid artery turndown technique from a single institution. Patients with interrupted aortic arch who ...
Cerimele Joseph M JM University of Washington School of Medicine, Department of Psychiatry and Behavioral Sciences, Box 356560, Seattle, WA 98195, USA. - - 2013
To systematically review the literature to determine if health risk behaviors in patients with schizophrenia or bipolar disorder are associated with subsequent symptom burden or level of functioning. Using the PRISMA systematic review method we searched PubMed, Cochrane, PsychInfo and EMBASE databases with key words: health risk behaviors, diet, obesity, ...
Momeni Arash A Division of Plastic and Reconstructive Surgery, Stanford University Medical Center, Palo Alto, CA 94304-5715, USA. - - 2013
The increasing incidence of breast cancer is paralleled by an increasing demand for post-mastectomy breast reconstruction. At the time of breast reconstruction routine submission of mastectomy scars has been considered appropriate clinical practice to ensure that no residual cancer exists. However, this practice has been challenged by some and has ...
Leeper Nicholas J NJ Division of Vascular Surgery, Department of Surgery, Stanford University School of Medicine, Stanford, CA, USA. - - 2013
The objective of this study was to assess the predictive value of clinical and exercise test variables in patients with peripheral arterial disease (PAD). A customized symptom-limited ramp treadmill protocol was used to assess 725 PAD patients referred for exercise testing at the Palo Alto Veterans Hospital between 1997 and ...
Marzano Michela M Université Paris Descartes, Philosophie morale, CERSES (UMR 8137), 75006 Paris, France. - - 2013
In the past, doctors did not hesitate to impose their point of view to patients. Today, informing patients and obtain their consent is the norm. But the patient is really in a position to make a decision about his health, when in a vulnerable situation? Which are the limits of ...
Addington Jean J Department of Psychiatry, University of Calgary, Calgary, Alberta, Canada. - - 2012
The North American Prodrome Longitudinal Study (NAPLS) is a consortium of eight programs focusing on the psychosis prodrome. Funded by the National Institute of Mental Health (NIMH), the sites are located at Emory University, Harvard University, University of Calgary, UCLA, UCSD, University of North Carolina Chapel Hill, Yale University, and ...
Garcia-Rill Edgar E Center for Translational Neuroscience, Department of Neurobiology & Dev. Sci., University of Arkansas for Medical Sciences, 4301 West Markham St., Slot 847, Little Rock, AR 72205, USA. - - 2013
This review considers recent evidence showing that cells in the reticular activating system (RAS) exhibit (1) electrical coupling mainly in GABAergic cells, and (2) gamma band activity in virtually all of the cells. Specifically, cells in the mesopontine pedunculopontine nucleus (PPN), intralaminar parafascicular nucleus (Pf), and pontine dorsal subcoeruleus nucleus ...
O'Connor Mary-Frances MF Department of Psychology, University of Arizona, Tucson, AZ 85721, USA. - - 2013
Could sympathetic hyperarousal limit treatment success in complicated grief? The present study investigated persons with complicated grief, a chronic condition with distinct symptoms including persistent intense yearning and longing for the person who died, avoidance of reminders that the person is gone, deep relentless sadness, self-blame, bitterness, or anger in ...
Aguilar-Ponce J L JL Department of Medical Oncology, Instituto Nacional de Cancerología, Mexico City, Mexico. - - 2013
Many studies have shown gemcitabine and cisplatin are radiosensitizers. Concurrent chemoradiation seems to be an efficient approach for treatment of advanced head and neck cancer (HNC), but toxicity is significant. To evaluate safety and explore efficacy of alternating chemotherapy with gemcitabine and cisplatin concurrent with radiotherapy in patients with advanced ...
Moon Sung-Hwan SH Division of Cardiology, Department of Medicine, Emory University School of Medicine, Atlanta, GA 30322, United - - 2013
Human pluripotent stem cells (hPSCs) hold great promise for treating ischemic heart disease. However, current protocols for differentiating hPSCs either result in low yields or require expensive cytokines. Here we developed a novel two dimensional (2D) stepwise differentiation system that generates a high yield of cardiomyocytes (CMs) from hPSCs without ...
Harris William S WS Sanford School of Medicine, University of South Dakota, Sioux Falls, SD, United States. - - 2013
Blood omega-3 and omega-6 fatty acid levels have been associated with reduced risk for total mortality in patients with stable coronary heart disease (CHD), but their relationships with mortality in the setting of myocardial infarction (MI) are unknown. To determine the association between red blood cell (RBC) fatty acid levels ...
Facette Michelle R - - 2012
Stomata are generated via asymmetric cell division in both dicots and monocots. Intrinsic or extrinsic polarity cues are perceived and acted upon to generate mother cell polarity and determine asymmetric division planes. Arabidopsis employs both intrinsic and extrinsic cues to orient a variable series of asymmetric stomatal divisions, using novel ...
Thubert Thibault - - 2012
OBJECTIVE: To compare complication rates and short-term outcomes of laparoscopic sacrocolpopexy among obese and non-obese women. METHODS: A retrospective multicenter study of 39 obese women and 111 non-obese women was conducted. Obesity was defined as a body mass index (BMI, calculated as weight in kilograms divided by the square of ...
Puffer Ross C - - 2012
OBJECTIVE: Previously we reported anterior decompression of C1-2 synovial cysts and subsequent posterior fusion in a large series. Although the surgical morbidity and mortality were acceptable, prior reports of stand alone C1-2 fusion with resolution of cyst compression presumptively by correction of joint instability were intriguing and obviated the need ...
Björkman Ingeborg - - 2012
BACKGROUND: In Sweden, a mass vaccination campaign against the influenza A(H1N1) 2009 resulted in 60% vaccination coverage. However, many countries had difficulty in motivating citizens to be vaccinated. To be prepared for future vaccination campaigns, it is important to understand people's reasons for not taking the vaccination. OBJECTIVE: The aim ...
Chowdhury Chiranjit - - 2012
Outer membrane vesicles (OMVs) are released from Pseudomonas syringae pv. tomato T1 (Pst T1) during their normal growth. These extracellular compartments are comprised of a complete set of biological macromolecules that includes proteins, lipids, lipopolysaccharides etc. It is evident from proteomics analyses the OMVs of Pst T1 contain membrane- and ...
Canan Chelsea E - - 2012
ABSTRACT: Study Design. Retrospective reviewObjective. To determine the incremental cost-effectiveness of cell saver for single-level posterior lumbar decompression and fusion (PLDF).Summary of Background Data. Intraoperative cell salvage is used during surgery to reduce the need for perioperative allogeneic blood transfusion. While the use of cell saver may be beneficial in ...
Ishii Shirou - - 2012
PURPOSE: The aim of this study was to compare uptake lesions in sarcoidosis and IgG4-related disease through gallium-67 (Ga) scintigraphy to differentiate between the two diseases. MATERIALS AND METHODS: Whole-body Ga scintigraphy findings of 27 patients with sarcoidosis and 16 with IgG4-related disease were reviewed between 2005 and 2011 at ...
Cha Soo-Min - - 2012
PURPOSE: To prospectively compare the clinical and radiological outcomes of 2 treatment methods for unstable distal ulna fractures associated with distal radius fractures in patients 65 years of age and older. METHODS: From February 2008 to March 2010, the first 29 ulnas were treated surgically (group 1) and the next ...
Zhan Yan-Yan - - 2012
The orphan receptor TR3 is an important regulator of cell proliferation and apoptosis. However, whether TR3 is involved in regulating the stem-like properties of cancer cells remains unknown. The present study shows that TR3 expression is increased in gastric tumorsphere cells and is positively correlated with cancer stem cell (CSC) ...
Ahmad Ejaj - - 2012
The development of a prophylactic vaccine against systemic candidiasis, employing Candida albicans cytosolic proteins (Cp) as antigen and fibrin cross-linked plasma beads as an antigen bearing dual delivery system is described. Groups of mice were administered with either free Cp, or Cp entrapped in plasma beads, Cp entrapped in liposomes ...
Bakhsh Turki A - - 2012
OBJECTIVES: This study investigated class-I cavity floor adaptation by swept-source optical coherence tomography (OCT) in combination with microtensile bond strength (MTBS) using different filling methods. METHODS: Two adhesive systems; Tokuyama Bond Force and Tri-S Bond Plus were used in conjunction with a universal composite (Estelite Sigma Quick) placed either incrementally ...
Yılmaz Engin - - 2012
Congenital scrotal agenesis is the rarest anomaly of scrotal development disorder and is characterized by the absence of scrotal rugae in the perineum between the penis and anus. We report here a case of hemiscrotal agenesis in a 2-year-old boy. To the best of our knowledge, our patient is the ...
Wascher Edmund - - 2012
Age related changes in frontal lobe functions are often related to attentional deficits that lead to increased distractibility by irrelevant stimuli. However, attentional functions have been reported not to decline in general with increasing age but simply be too slow to deal properly with distraction in time. Therefore older people ...
Ramírez-Rodríguez Gerardo - - 2012
Melatonin modulates adult hippocampal neurogenesis in adult mice. Also, plasma melatonin levels and new neuron formation decline during aging probably causing cognitive alterations. In this study, we analyzed the impact of exogenous supplementation with melatonin in three key events of hippocampal neurogenesis during normal aging of mice. The analysis was ...
Esfandiarpour Fateme - - 2012
BACKGROUND: Studying the kinematics of the ACL deficient (ACLD) knees, during different physiological activities and muscle contraction patterns, can improve our understanding of the joint's altered biomechanics due to ACL deficiency as well as the efficacy and safety of the rehabilitations exercises. METHODS: Twenty-five male volunteers, including 11 normal and ...
Ozkaya Esen - - 2012
BACKGROUND: Little is known about the characteristic features of oral mucosal fixed drug eruption (FDE). OBJECTIVE: To present the clinical highlights and the differential diagnosis of oral mucosal FDE in a relatively large group of patients from Turkey. METHODS: This was a methodological, retrospective, cross-sectional study of 61 patients with ...
Susa Koichiro - - 2012
Blood pressure and renal salt excretion show circadian rhythms. Recently, it has been clarified that clock genes regulate circadian rhythms of renal transporter expression in the kidney. Since we discovered the WNK-OSR1/SPAK-NaCl cotransporter (NCC) signal cascade, which is important for regulating salt balance and blood pressure, we have sought to ...
Deponte Marcel - - 2012
Quite aside from it's immense importance as a human pathogen, studies in recent years have brought to light the fact that the malaria parasite P. falciparum is an interesting eukaryotic model system to study protein trafficking. Studying parasite cell biology often reveals an overrepresentation of atypical cell biological features, possibly ...
Kantovitz Kamila Rosamilia - - 2012
OBJECTIVES: This study evaluated the effect of fluoride and non-fluoride sealants on hardness decrease (HD) and marginal adaptation (MA) on enamel substrates after cariogenic challenge. METHODS: Occlusal enamel blocks, from human third molars, were randomly divided into six groups (n=12), according to occlusal fissures condition (S-sound; C-caries-like lesion; CF-caries-like lesion+topical ...
Makiyama Tomohiko - - 2012
Ceramide-1-phosphate (C1P) has been shown to bind with C2 domain in group IVA cytosolic phospholipase A(2) (cPLA(2)α, PLA2G4A) and activate the enzyme activity directly. In cells, C1P causes translocation of cPLA(2)α to perinuclear regions including the Golgi complex by interacting with C2 domain in the enzyme, and then cPLA(2)α releases ...
Biro Jan C - - 2012
Transfer RNA molecules (tRNA) have the thermodynamic potential to interact with each other to form dimers (hybridization energy, dG=-33.2±6.7kcal/mole, compared to the folding energy of the cloverleaf configuration, dG=-25±4.4kcal/mole, p<0.0001). The dG values have a strong negative correlation with the frequency of co-locations and substitutions of associated amino acids. We ...
Liu Tianqing - - 2012
This study was designed to demonstrate the potential of small nanoparticulate lymphotropic contrast agents designed to bind with high affinity to lymphoid cells overexpressing the CD45 antigen. To this end, small gold nanoparticles used as model were conjugated to anti-CD 45 antibodies and injected in mice in the dorsal toe ...
Tapia-Pérez J Humberto - - 2012
OBJECTIVE: In our previous study, we had suggested the usefulness of cerebral endoscopy as a therapeutic option for hydrocephalus due to neurocysticercosis (NCC). Now, we propose a scoring system for the assessment of the inflammatory alterations caused by NCC inside the ventricular cavities and the basal subarachnoid space. METHODS: We ...
Vivancos J - - 2012
OBJECTIVE: To update the Spanish Society of Neurology's guidelines for subarachnoid haemorrhage diagnosis and treatment. MATERIAL AND METHODS: A review and analysis of the existing literature. Recommendations are given based on the level of evidence for each study reviewed. RESULTS: The most common cause of spontaneous subarachnoid haemorrhage (SAH) is ...
Chesney Russell W - - 2012
Despite several recent studies, the advisability of antimicrobial prophylaxis and certain imaging studies for urinary tract infections (UTIs) remains controversial. The role of vesicoureteral reflux (VUR) on the severity and re-infection rates for UTIs is also difficult to assess. Registries and repositories of data and biomaterials from clinical studies in ...
Bryan Nathan S - - 2012
Over the past ten years, despite a slight increase in life expectancy and a decrease in all causes of deaths, the percentage of the US population with heart disease, cancer, diabetes, hypertension and obesity has increased. So even though Americans are living longer, they are plagued by increasing incidences of ...
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