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Sentic Milica - - 2012
Swimmer in the dark: Propulsion of a conducting object is intrinsically coupled with light emission using bipolar electrochemistry. Asymmetric redox activity on the surface of the swimmer (black bead; see picture) causes production of gas bubbles to propel the swimmer in a glass tube with simultaneous electrochemiluminescence (ECL) emission to ...
Holley Tracey A - - 2012
The crystal structure of Sco5413 from Streptomyces coelicolor A3(2) has been determined at 1.25 Å resolution, the highest resolution reported for a MarR family transcriptional regulator. Putative orthologs are encoded by the majority of sequenced actinomycete genomes, and may play roles in regulating growth and antibiotic production, but they have ...
Durand Caylib A - - 2012
During the progression of autoimmune (type 1) diabetes, T cells and macrophages infiltrate the pancreas, disrupt islet function, and destroy insulin-producing beta cells. B-lymphocytes, particularly innate like B-cell populations such as marginal zone B cells and B-1 cells, have been implicated in many autoimmune diseases, and non-obese diabetic (NOD) mice ...
Akhtar Hashaam - - 2012
ABSTRACT: BACKGROUND: Transgender males are at high risk for sexually transmitted diseases including AIDS caused by the notorious Human Immunodeficiency Virus (HIV), yet little consideration is given by the policy makers, researchers and non-governmental organizations (NGOs) towards this sensitive issue in Pakistan. METHODS: In this study, we have investigated the ...
Zhou Wei - - 2012
High-pressure synchrotron x-ray powder diffraction experiments were performed on PbVO(3) tetragonal perovskite in a diamond anvil cell under hydrostatic pressures of up to 10.6 GPa at room temperature. The compression behavior of the PbVO(3) tetragonal phase is highly anisotropic, with the c-axis being the soft direction. A reversible tetragonal to cubic ...
Cv Bellieni - - 2012
Abstract Aim: To compare the analgesic effect of 3 treatments to relieve the pain produced by intramuscular injections (IMI) in term newborns, and to assess sex-linked differences in their response to pain. Material and methods: We studied 62 babies. Each baby received antibiotic IMIs for clinical aims. During each IMI, ...
Kobr Lukáš - - 2012
Hexagonal tris(o-phenylenedioxy)cyclotriphosphazene (TPP) is used as ahost for organizing dipolar molecular rotor guests into regular trigonal arrays. Inclusion of molecular rotors with transversely dipolar rotators into TPP channels is followed by solid-state nuclear magnetic resonance, diifferential scanning calorimetry, X-ray diffraction, and dielectric spectroscopy. The more polar of the two rotors ...
Belecki Katherine - - 2012
A light in the dark: the fermentation products of the polyketide synthase CalE8 (without its cognate thioesterase) were identified and gave some insight into the elusive early steps of calicheamicin biosynthesis. Fermentation in either the light or dark resulted in different proportions of a new octaketide and led to an ...
Wulferding Dirk - - 2012
The spin dynamics and magnetic excitations of the slightly distorted triangular s = 3/2 system α-CaCr (2)O (4) are investigated by means of Raman spectroscopy and electron spin resonance (ESR) to elucidate its peculiar magnetic properties. Two-magnon excitations in circular RL symmetry show a multi-maximum structure with a dominant spectral weight at ...
Mangera Altaf - - 2013
The field of tissue engineering is rapidly progressing. Much work has gone into developing a tissue engineered urethral graft. Current grafts, when long, can create initial donor site morbidity. In this article, we evaluate the progress made in finding a tissue engineered substitute for the human urethra. Researchers have investigated ...
Bender Georg - - 2012
The five-membered zirconacycloallenoids react rapidly with dihydrogen under mild conditions to yield the corresponding (s-cis-conjugated diene)zirconocenes . The reaction involves splitting of the H(2) molecule between the metal center and a ligand carbon atom.
Wu Qian - - 2012
Interferon (IFN)-λ1 is a newly described cytokine that is known for its proinflammatory activity in viral infection and in cancer. Since Because recent studies indicated that IFN-λ can influence significantly the innate and adaptive immune response, we studied IFN-λ in a prototypic systemic autoimmune disease, rheumatoid arthritis (RA). It was ...
Bakitas Marie - - 2012
Objective: The purpose of this study was to understand oncology clinicians' perspectives about the care of advanced cancer patients following the completion of the ENABLE II (Educate, Nurture, Advise, Before Life Ends) randomized clinical trial (RCT) of a concurrent oncology palliative care model. Method: This was a qualitative interview study ...
Taucher Monika - - 2012
Characteristic mass differences between fragment ions from backbone cleavage of RNA by electron detachment (d, w) and fragment ions from collisionally activated dissociation (c, y) provide extensive sequence information. Structure analysis by this approach should be especially useful for the detailed characterization of synthetic or post-transcriptionally modified RNA.
de Mascena Diniz Maia Paula Ferdinanda Conceição - - 2012
Abstract IGF2 gene has an important role in fetal growth. It was investigated association of the IGF2/ApaI polymorphism with low birth weight and normal birth weight (as control) in children attended in Hospital Dom Malan Petrolina, PE-Brazil. The genotype frequencies did not differ statistically between low birth weight (AA = ...
Baik Ran - - 2012
Aims:  We evaluated echocardiography and electrocardiography (ECG) results in children with non-specific mitochondrial disease (MD) in order to study early cardiac involvement, a well-known complication of the disease. Methods:  Among non-specific MD children whose isolated mitochondrial respiratory chain complex I defect was confirmed by muscle biopsy and satisfied the criteria ...
Hindocha Sumeet - - 2012
Early diagnosis of human immunodeficiency virus (HIV) leads to a decreased morbidity and mortality. General practice offers an important window for earlier diagnosis. The British HIV Association produced guidelines in 2008 advocating an increase in HIV testing, with specific references to primary care. This study explores the awareness of, and ...
- - 2012
My favorite pieces of music are Beethoven's symphonies. If I were not a scientist, I would be a chef in a restaurant.
Müller Thomas - - 2012
From analysis towards synthesis: Charged microdroplets act as microreaction vessels, extending the use of electrospray mass spectrometry from chemical analysis to synthesis. Application of this unique reaction conditions allows microscale carbon-carbon bond forming reactions to be performed rapidly and in high yields.
Johnsen Anna Thit - - 2012
OBJECTIVES: The aim of the study was to investigate the adequacy of help delivered by the healthcare system for 12 symptoms/problems in a national, randomly selected sample of advanced cancer patients in Denmark. METHODS: Advanced cancer patients (n = 1630) from 54 hospital departments across Denmark received the 3-Levels-of-Needs Questionnaire (3LNQ). The ...
Reyes-Esparza Jorge - - 2012
In the present study, we evaluated the effect of an analogue of L-carnitine on parameters involved with Metabolic Syndrome in obese Zucker rats. Twenty-four rats were treated for five weeks with L-carnitine (300 mg/kg) and its analogue at two concentrations (100 and 250 mg/kg) to assess their impact on glucose, ...
Cader Rizna A - - 2012
AIMS AND OBJECTIVES: To assess the degree of overhydration in our peritoneal dialysis patients and to examine the factors contributing to overhydration. BACKGROUND: Volume control is critical for the success of peritoneal dialysis, but dry weight has been difficult to ascertain accurately. Chronic fluid overload and hypertension are among the ...
Yang Mei-Ling - - 2012
Modifications of both DNA and protein by methylation are key factors in normal T and B cell immune responses as well as in the development of autoimmune disease. For example, the failure to maintain the methylation status of CpG dinucleotides in DNA triggers T cell autoreactivity. Methylated proteins are known ...
Arabin Birgit - - 2012
Abstract Aim of the study: Studies investigating the impact of pre- or postnatal music exposure on child development are scarce. Therefore we conducted this pilot study. Material and Methods: Five hundred pregnant women, 246 primigravidae and 254 multigravidae were interviewed about listening to, singing and performing music during pregnancy and ...
Humphries T J - - 2012
Pain is a critical aspect in the lives of individuals with congenital haemophilia A or B. Initially, pain serves as a warning sign for an active bleeding event; however, after multiple bleeding episodes, pain may become chronic, debilitating, and distracting. It is essential that pain instruments be developed and validated ...
Luo Shaobo - - 2012
The aim of this study was to investigate the impact of a Chinese herbal decoction on the intracellular calcium (Ca2+) concentration of sperm and the expression of the cation channel 1 of sperm (CatSper1), which is a calcium-channel protein specific to sperm tail, in a murine model of asthenospermia induced with ...
Roy Babhrubahan - - 2012
High fidelity chromosome segregation is essential for efficient transfer of the genetic material from the mother to daughter cells. The kinetochore, which connects the centromere DNA to the spindle apparatus, plays a pivotal role in this process. In spite of considerable divergence in the centromere DNA sequence, basic architecture of ...
Lok Sheau Wen - - 2012
BACKGROUND: Congenital heart disease is common yet poorly understood in childhood. We reviewed the understanding of older children and adolescents of the commonest congenital heart defect namely a small ventricular septal defect (VSD) through a questionnaire and/or their drawings of their abnormality. METHODS: As part of a wider study older ...
Morikawa Masa-Aki - - 2012
β-Nicotinamide adenine dinucleotide (NAD(+)) and its reduced form NADH specifically interact with a cyanine dye in aqueous media, giving distinct spectral and nanostructural characteristics to which molecular information of constituent coenzymes are converted via self-assembly.
Hare Jennifer I - - 2012
Purpose: We used two ligand-modified liposomal drugs to selectively deliver two different chemotherapeutics to tumor cells (TC) and tumor vasculature endothelial (TV) cells, and examined the therapeutic effect of altering the order of treatment administration, and the effect of the temporal spacing of the treatments on the accumulation of a ...
Napierska Dorota - - 2012
There is evidence that nanoparticles can induce endothelial dysfunction. Here, the effect of monodisperse amorphous silica nanoparticles (SiO(2) -NPs) of different diameters on endothelial cells function is examined. Human endothelial cell line (EA.hy926) or primary human pulmonary artery endothelial cells (hPAEC) are seeded in inserts introduced or not above triple ...
Li Yingke Y Department of Anesthesiology, Changzheng Hospital, Second Military Medical University, Shanghai 200003, - - 2012
Effective recognition of viral infections and subsequent triggering of antiviral innate immune responses are essential for the host antiviral defense, which is tightly regulated by multiple regulators, including microRNAs (miRNAs). A previous study showed that miR-466l upregulates IL-10 expression in macrophages by antagonizing RNA-binding protein tristetraprolin-mediated IL-10 mRNA degradation. However, ...
Hammoud Ahmad O - - 2012
Vitamin D levels have been linked to various health outcomes including reproductive disorders. The purpose of this study was to explore the association between serum vitamin D level (25-hydroxy-vitamin D, or 25OHD) and semen and hormonal parameters. This is a cross-sectional study that included 170 healthy men recruited for the ...
Hoshi Akio - - 2012
OBJECTIVES: To describe a novel dorsal vein complex preserving technique for intrafascial nerve-sparing laparoscopic radical prostatectomy and to evaluate its postoperative outcomes. METHODS: A total of 109 patients who underwent laparoscopic radical prostatectomy by a single surgeon were evaluated, including 44 patients with dorsal vein complex preserving technique for intrafascial ...
Könning Daniel - - 2012
A method for generating (E)-α,β-unsaturated aldehydes from Z-allylic alcohols or E/Z-mixtures is described. The one-pot procedure involves a Cu-catalyzed oxidation followed by an organocatalytic Z/E-isomerization with N,N-dimethylaminopyridine (DMAP).
Langer Oded - - 2012
Abstract The new criteria for diagnosis of gestational diabetes mellitus proposed by the International Diabetes in Pregnancy Consensus group (IADPSG) transports back the controversy and the lack of agreement to the frontlines. The recommended criteria are based on results of the observational hyperglycemia and adverse pregnancy outcome study (HAPO). These ...
Lee Robert J - - 2012
Innate and adaptive defense mechanisms protect the respiratory system from attack by microbes. Here, we present evidence that the bitter taste receptor T2R38 regulates the mucosal innate defense of the human upper airway. Utilizing immunofluorescent and live cell imaging techniques in polarized primary human sinonasal cells, we demonstrate that T2R38 ...
Kujawska Małgorzata - - 2012
The aim of the study was to evaluate a protective effect of apple juice on KBrO(3) -induced oxidative stress in rats. Male Wistar rats were administered apple juice per os, 10 ml/kg b.w. for 28 days. On 27 day of the experiment, some rats were given i.p. a single 125 mg/kg b.w. dose of ...
Maher Nicola - - 2012
Abstract In this centre women with a history of gestational diabetes (GDM) are treated without rescreening from early pregnancy in any subsequent pregnancies, commencing with a low glycaemic diet and insulin if and when indicated. The objective of this study was to see if this practice reduced the incidence of ...
Hjorthøj C R - - 2012
BACKGROUND: Cannabis abuse in psychotic patients is associated with rehospitalizations, reduced adherence and increased symptom severity. Previous psychosocial interventions have been ineffective in cannabis use, possibly because of low sample sizes and short interventions. We investigated whether adding CapOpus to treatment as usual (TAU) reduces cannabis use in patients with ...
Cruise Sharon - - 2012
Aim:  Chloral hydrate is generally considered a safe and effective single dosing procedural sedative for neonates in the clinical setting. However, its safety profile as a repetitive dosing maintenance sedative is largely unknown. This study aimed to document current administration practices of chloral hydrate in the Neonatal Unit, Royal Children's ...
Mitchell Meghan B - - 2012
Accurate measurement of cognitive function is critical for understanding the disease course of Alzheimer's disease (AD). Detecting cognitive change over time can be confounded by level of premorbid intellectual function or cognitive reserve and lead to under- or over-diagnosis of cognitive impairment and AD. Statistical models of cognitive performance that ...
Saleta M E - - 2012
Vanadium oxide nanotubes constitute promising materials for applications in nanoelectronics as cathode materials, in sensor technology and in catalysis. In this work we present a study on hybrid vanadium oxide/hexadecylamine multiwall nanotubes doped with Co ions using state of the art x-ray diffraction and absorption techniques, to address the issue ...
Rice B - - 2012
SUMMARY We examined the uptake of HIV testing in black Africans living in England before the introduction of national testing guidelines. Analyses were conducted using data from an anonymous self-completed questionnaire linked to oral fluid samples to establish HIV status in black Africans attending community venues in England in 2004. ...
Colquhoun Samantha M - - 2012
We designed a pilot study of a training module for nurses to perform rheumatic heart disease echocardiography screening in a resource-poor setting. The aim was to determine whether nurses given brief, focused, basic training in echocardiography could follow an algorithm to potentially identify cases of rheumatic heart disease requiring clinical ...
Tavares Adriana Alexandre S - - 2012
This study aims to investigate the pharmacokinetics of a recently developed radiotracer for imaging of the norepinephrine transporter (NET) in baboon brain, (123) I-INER, using single photon emission computed tomography (SPECT). In addition, it also aims to determine NET occupancy by atomoxetine and reboxetine, two selective norepinephrine reuptake inhibitors, using ...
Howie E K EK Department of Exercise Science, University of South Carolina, Columbia, SC, USA. - - 2013
Understanding the physical activity behaviour of young children who are highly active may provide important guidance for promoting physical activity in preschools. The objective of this study was to describe the movement characteristics of high-active (HA) children during attendance at preschools. Children in 20 preschools (n = 231) wore accelerometers and were ...
Kamradt-Scott Adam - - 2012
Abstract This article examines how pandemic influenza has been framed as a security issue, threatening the functioning of both state and society, and the policy responses to this framing. Pandemic influenza has long been recognised as a threat to human health. Despite this, for much of the twentieth century it ...
Simonin Vagner - - 2012
Nitric oxide (NO) is described as an inhibitor of plant and mammalian respiratory chains due to its high affinity for cytochrome c oxidase (COX), which hinders reduction of oxygen to water. Here we show that in plant mitochondria NO may interfere with other respiratory complexes as well. We analyzed oxygen ...
Shipe Nancy K - - 2012
Objectives To assess intra-rater and inter-rater reliability of the tragus wall distance (TWD) measurement in non-pathologic individuals aged 18-34. Background: Physical therapists evaluate posture as a component of health status. A literature review suggests need for reliable clinical tools to assess head position. Methods: The TWD measurement is the horizontal ...
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