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Craig Evisabel A EA Department of Dermatology, University of Wisconsin School of Medicine and Public Health, Madison, WI 53706, - - 2012
We have previously shown that the mRNA binding protein CRD-BP is overexpressed in human melanomas, where it promotes cell survival and resistance to chemotherapy. The present study investigates the role of hypoxia, a common characteristic of the tumor microenvironment, in the regulation of CRD-BP expression and melanoma cell responses. We ...
Martínez Inés I Department of Food Science and Technology, University of Nebraska, Lincoln, NE 68583, - - 2013
The involvement of the gut microbiota in metabolic disorders, and the ability of whole grains to affect both host metabolism and gut microbial ecology, suggest that some benefits of whole grains are mediated through their effects on the gut microbiome. Nutritional studies that assess the effect of whole grains on ...
Kim Hye Sung - - 2012
ABSTRACT: INTRODUCTION: TLR4 promotes joint inflammation in mice. Despite that several studies report a functional link between TLR4 and IL-1in arthritis, TLR4-mediated regulation of the complicated cytokine network in arthritis is poorly understood. To address this, we investigated the mechanisms by which TLR4 regulates the cytokine network in antibody-induced arthritis. ...
Kosicka Anna - - 2012
Obesity-related metabolic disorders are characterized by mild chronic inflammation, leukocyte infiltration, and tissue fibrosis as a result of adipocytokine production from the expanding white adipose tissue. Annexin A1 (AnxA1) is an endogenous glucocorticoid regulated protein, which modulates systemic anti-inflammatory processes and, therefore, may be altered with increasing adiposity in humans. ...
Berg Karl S - - 2012
Parrots rely heavily on vocal signals to maintain their social and mobile lifestyles. We studied vocal ontogeny in nests of wild green-rumped parrotlets (Forpus passerinus) in Venezuela. We identified three successive phases of vocal signaling that corresponded closely to three independently derived phases of physiological development. For each ontogenetic phase, ...
Imayama Ikuyo - - 2012
BACKGROUND: Regular exercise increases exercise self-efficacy and health-related quality of life (HRQOL); however, the mechanisms are unknown. We examined the associations of exercise adherence and physiological improvements with changes in exercise self-efficacy and HRQOL. METHODS: Middle-aged adults (N=202) were randomized to 12 months aerobic exercise (360 minutes/week) or control. Weight, ...
Pruden Amy - - 2012
Antimicrobial resistance remains a serious and growing human health challenge. The water environment may represent a key dissemination pathway of resistance elements to and from humans. However, quantitative relationships between landscape features and antibiotic resistance genes (ARGs) have not previously been identified. The objective of this study was to examine ...
Mahadevan Raynuha - - 2012
Introduction.  Decreased libido is recognized as one of the vegetative symptoms of depression. Increased libido has not been acknowledged as one of its symptoms, neither has it been reported, particularly in depressed bipolar patients. Aim.  We hereby report a case of atypical presentation of increased sexual function in a patient ...
Wu F - - 2012
The main objective of this study was to investigate the pharmacokinetic characters of eszopiclone (CAS: 138729-47-2) after single and multiple-dose oral administration in healthy adult Chinese volunteers.In single-dose study, 12 subjects were given oral administrations of 1.5, 3 and 6 mg eszopiclone in an open-label, randomized, crossover fashion. In multiple-dose study, ...
Ritchie David - - 2012
Criteria used in the evaluation and selection of applicants for clinical neuropsychology internships were identified by a survey of programs that met guidelines for specialty training. The number of internships that offer training with specialization in clinical neuropsychology has more than doubled during the past 10 years. Supervising neuropsychologists from ...
Tu Yawei - - 2012
The radical cyclization between aliphatic acyclic esters and alkenes was achieved unprecedentedly in the presence of allylsamarium bromide with HMPA and H(2)O as additives. The cascade radical cyclization-ring-opening-anionic cyclization allowed facile and efficient access to 2-(2-hydroxyalkyl)cyclopropanols from readily available materials.
Washington Karla T KT Kent School of Social Work, University of Louisville, Louisville, Kentucky 40292, USA. - - 2013
The ACTIVE (Assessing Caregivers for Team Intervention through Video Encounters) intervention uses technology to enable family caregivers to participate in hospice interdisciplinary team (IDT) meetings from geographically remote locations. Previous research has suggested that effective communication is critical to the success of these meetings. The purpose of this study was ...
Kroes Geert-Jan - - 2012
This perspective addresses four challenges facing theorists whose aim is to make quantitatively accurate predictions for reactions of molecules on metal surfaces, and suggests ways of meeting these challenges, focusing on dissociative chemisorption reactions of H(2), N(2), and CH(4). Addressing these challenges is ultimately of practical importance to a more ...
Shoja Mohammadali M - - 2012
Today, the study of human anatomy utilizing the ultimate study guide, the cadaver, is relatively safe. In the past, however, human dissection was dangerous. Prior to the germ theory, antibiotics, and the use of gloves, cadavers were often life threatening to dissectors including both the teacher and the student. Medical ...
Lee Yu Kyung - - 2012
1. Protein-calorie malnutrition (PCM) could occur frequently in cancer patients and alter the pharmacokinetics of drugs. Also cysteine shows anti-oxidative effect and changes the activities of drug metabolizing enzyme and/or transporters. Herein, we investigated the effects of cysteine on the pharmacokinetics of tamoxifen in rats with protein-calorie malnutrition (PCM). 2. The in ...
Nomoto Yuji - - 2012
The plant circadian clock generates rhythms with a period close to 24 h, and it controls a wide variety of physiological and developmental events, enabling plants to adapt to ever-changing environmental light conditions. In Arabidopsis thaliana, the clock regulates the diurnal and photoperiodic plant growth including the elongation of hypocotyls ...
Gauri Samiran S - - 2012
AIMS: To examine tannic acid (TA) utilization capacity by nitrogen fixing bacteria, Azotobacter sp. SSB81 and identify the intermediate products during biotransformation. Another aim of this work is to investigate the effects of TA on major biopolymers (EPS and PHB) synthesis. METHODS AND RESULTS: Tannic acid utilization and tolerance capacity ...
King Brenee S BS Department of Pharmaceutical Sciences, College of Pharmacy, University of New Mexico, Albuquerque, New Mexico 87131, - - 2012
Exposure to ultraviolet radiation (UVR) promotes the formation of UVR-induced, DNA helix distorting photolesions such as (6-4) pyrimidine-pyrimidone photoproducts and cyclobutane pyrimidine dimers. Effective repair of such lesions by the nucleotide excision repair (NER) pathway is required to prevent DNA mutations and chromosome aberrations. Poly(ADP-ribose) polymerase-1 (PARP-1) is a zinc ...
Xu Xiao - - 2012
A simple and rapid bacterial counting method was developed based on dark-field light-scattering imaging of bacteria and gold nanoparticle (AuNP) reporter simultaneously. Commercially available DH5α E. coli strain was used as the model bacterium to demonstrate the feasibility of the proposed method. With antibody-conjugated AuNPs, the simple sample treatment and ...
Zhang Yi - - 2012
ABSTRACT: BACKGROUND: Cardiac structure and function are well-studied in western countries. However, epidemiological data is still scarce in China. METHODS: Our study was conducted in the framework of cardiovascular health examinations for the current and retired employees of a factory and their family members. According to the American Society of ...
Di Minno Matteo Nicola Dario - - 2012
ABSTRACT: INTRODUCTION: We prospectively evaluated whether hepatic steatosis (HS) and the presence of carotid plaques (CPs) impacts on achieving minimal disease activity (MDA) in psoriatic arthritis (PsA) patients starting tumor necrosis factor (TNF)-alpha blockers treatment. METHODS: Before starting treatment with TNF-alpha blockers, consecutive PsA subjects with an active disease were ...
Zhao Yang - - 2012
Abstract Objective: To investigate the clinical characteristics of mirror syndrome. Methods: Retrospective analysis of cases with mirror syndrome. Data of clinical manifestations, laboratory examinations, placental morphology, treatment and prognosis of these patients were obtained and studied. Results: Five cases satisfying the inclusion criteria for mirror syndrome were identified from our ...
Toran Laura - - 2012
A freeze core sampler was used to characterize hyporheic zone storage during a stream tracer test. The pore water from the frozen core showed tracer lingered in the hyporheic zone after the tracer had returned to background concentration in collocated well samples. These results confirmed evidence of lingering subsurface tracer ...
Tierney Travis S - - 2012
Surgical therapy for the secondary dystonias is generally perceived to be less effective than for primary disease. However, a number of case reports and small open series have recently appeared describing quite favorable outcomes following surgery for some nonprimary dystonias. We discuss surgical treatment options for this group of diverse ...
Eloy Jean Anderson - - 2012
BACKGROUND: Endoscopic endonasal transcribriform (EET) resection of anterior skull base (ASB) tumors results in large defects that may extend the entirety of the cribriform plate. Endoscopic repair of these cribriform defects can often be challenging. We describe our reconstruction technique for large ASB defects after EET resection of ASB tumors. ...
Okawa Makio - - 2012
OBJECTIVE: Prior to 2003, the target blood glucose level at our institute was <200 mg/dl. This target was reassessed in 2004 and again in 2006 based on reports that showed a decreased mortality rate in patients with a target glucose level between 80 mg/dl and 110 mg/dl and subsequent reports ...
Yoshinari Takeshi - - 2012
Babesia ovata is a tick-transmitted hemoprotozoan parasite that infects cattle. In our study, bovine blood samples (n=2,034) were collected from 10 different countries (Brazil, China, Ghana, Japan, Mongolia, the Philippines, South Africa, Sri Lanka, Thailand, and Vietnam) and DNA extracted. The DNA samples were screened using an established and specific ...
Tronic Tristan A - - 2012
Cyclopentadienyl and pentamethylcyclopentadienyl ruthenium(II) complexes have been synthesized with cyclic (RPCH(2)NR'CH(2))(2) ligands, with the goal of using these [Cp(R'')Ru(P(R)(2)N(R')(2))](+) complexes for catalytic O(2) reduction to H(2)O (R = t-butyl, phenyl; R' = benzyl, phenyl; R″ = methyl, H). In each compound, the Ru is coordinated to the two phosphines, positioning ...
Song Zhiguang - - 2012
In this study silica nanoparticles (SiNPs) were covalently modified by the fluorescence ligand 2-((7-oxo-7H- furo [3, 2-g] chromen-9-yl) oxy)-N-(3-(triethoxysilyl) propyl) acetamide (CTPA) and provided an optical sensor allowing highly sensitive and selective detection for Au(3+). The probe exhibited a dynamic response range for Au(3+) from 5.0 × 10(-7) to 1.0 × 10(-4) M, with a ...
Zeng Xianghui - - 2012
Dendrimers and their less well defined cousins, hyperbranched polymers, are widely investigated as scaffold materials in tissue engineering, as drug delivery agents, and in diagnostic imaging applications. Despite the large interest of using these unique materials as polymer based nanoparticles in biomedical applications, a clear understanding of the cellular uptake ...
Kovacs Jozsef - - 2012
Anderson and Dyck claim that the current trend of almost exclusively using citation-based evaluative metrics to assess the research output of scholars is unsound. I agree with them in this, but I feel that, for practical reasons, this system will not disappear in the near future, so we must concentrate ...
Viola Tracey - - 2012
This was a study that surveyed state medical licensing boards in the USA, to see if they have laws or exemptions for travelling team physicians to practice medicine on their own team, while travelling to that state. Surveys were sent to 58 medical boards, with legislative data being obtained for ...
Alfieri Alessio - - 2012
ABSTRACT: INTRODUCTION: Severe sepsis is characterized by intravascular or extravascular infection with microbial agents, systemic inflammation and microcirculatory dysfunction, leading to tissue damage, organ failure and death. The growth factor angiopoietin-1 (Ang-1) has therapeutic potential but recombinant Ang-1 tends to aggregate and has a short half life in vivo. This ...
Goodman Robert L RL Department of Physiology and Pharmacology, Robert C. Byrd Health Sciences Center, Morgantown, WV 26506, USA. - - 2012
Recent work has implicated stimulatory kisspeptin neurons in the arcuate nucleus (ARC) as important for seasonal changes in reproductive function in sheep, but earlier studies support a role for inhibitory A15 dopaminergic (DA) neurons in the suppression of GnRH (and LH) pulse frequency in the nonbreeding (anestrous) season. Because A15 ...
Chan Sum Yee SY The Courtyard Clinic, Blackshaw Road, Tooting, London SW17 0QT, UK. - - 2013
Environmental contamination with DNA from Chlamydia trachomatis (CT) has previously been found in Genitourinary Medicine (GUM) clinics. There are no known cases of cross-contamination of clinical samples and no known nosocomial infections. We investigated whether diagnostic samples could become contaminated from the environment by running dummy sample and carrying out ...
Duchnowska Renata - - 2012
Neurological symptoms are uncommon in patients administered sunitinib therapy; however, a few cases of dramatic neurotoxicity attributable to the development of reversible posterior leukoencephalopathy syndrome have been reported. Here, we report a case of a 71-year old woman with severe neurological symptoms occurring during sunitinib therapy for metastatic renal cell ...
Stanton Jennifer S - - 2012
A previously published regional groundwater-flow model in north-central Nebraska was sequentially linked with the recently developed soil-water-balance (SWB) model to analyze effects to groundwater-flow model parameters and calibration results. The linked models provided a more detailed spatial and temporal distribution of simulated recharge based on hydrologic processes, improvement of simulated ...
Takebayashi Takashi - - 2012
Objective:To investigate the long-term effects of the 'transfer package' in constraint-induced movement therapy, which is an optional protocol to facilitate actual use of the trained affected arm in activities of daily living.Design:A pilot quasi-randomized controlled trial with a blinded single assessor with six-month follow-up.Setting:Hospitalized care at university hospital.Subjects:Twenty-one post-stroke patients ...
Mohapatra Hemakesh - - 2012
Smell of success: Reagent 1 provides the dual readouts of odor (ethanethiol) and fluorescence (derivative of 7-hydroxycoumarin) and can be used in down-selection assays based on smell and quantitative fluorescence assays of the samples that give a positive result. An important feature of 1 is the matched sensitivity of the ...
Oderda Marco - - 2012
Abstract Objective. Leiomyomata are benign neoplasms that are rarely encountered in the genitourinary tract outside the uterus. Pathological confirmation is always needed for definitive diagnosis, in order to rule out malignancies such as leiomyosarcoma. In cases of small leiomyomata, a surveillance strategy can be suggested, although the preferred approach is ...
Liversidge Helen M - - 2012
Background: A frequently reported advancement in dental maturity compared with the 50(th) percentile of Demirjian, Goldstein and Tanner (1973, Hum Biol 45:211-27) has been interpreted as a population difference. Aim: To review the assessment and interpretation of Demirjian et al.'s dental maturity. Subjects and methods: Dental maturity of boys from ...
Sigel Erwin E Institute of Biochemistry and Molecular Medicine, University of Bern, CH-3012 Bern, Switzerland. - - 2012
The GABA(A) receptors are the major inhibitory neurotransmitter receptors in mammalian brain. Each isoform consists of five homologous or identical subunits surrounding a central chloride ion-selective channel gated by GABA. How many isoforms of the receptor exist is far from clear. GABA(A) receptors located in the postsynaptic membrane mediate neuronal ...
Kim Dongwon - - 2012
Lipid profiles in wheat leaves and the effects of tan spot on the profiles were quantified by mass spectrometry. Inoculation with Pyrenophora tritici-repentis significantly reduced the amount of many leaf lipids, including the major plastidic lipids monogalactosyldiacylglycerol (MGDG) and digalactosyldiacylglycerol (DGDG), which together accounted for 89% of the mass spectral ...
Lawson Jr Larry L - - 2012
The initial version (v1) of the Fish Invasiveness Scoring Kit (FISK) was adapted from the Weed Risk Assessment of Pheloung, Williams, and Halloy to assess the potential invasiveness of nonnative freshwater fishes in the United Kingdom. Published applications of FISK v1 have been primarily in temperate-zone countries (Belgium, Belarus, and ...
Pitino Marco - - 2012
Microbial pathogens and pests produce effectors to modulate host processes. Aphids are phloem-feeding insects, which introduce effectors via saliva into plant cells. However, it is not known if aphid effectors have adapted to modulate processes in specific plant species. Myzus persicae is a polyphagous insect that colonizes Arabidopsis thaliana and ...
Dart Anna E - - 2012
Phagocytosis is the force-dependent complex cellular process by which immune cells engulf particles. Whilst there has been considerable progress in understanding ligand-receptor-induced actin polymerization in pushing the membrane around the particle, significantly less is known about how localized contractile activities regulate cup closure in coordination with the actin cytoskeleton. Herein, ...
Aguila Jerell R - - 2012
Within the complex life cycle of holometabolous insects, nutritional resources acquired during larval feeding are utilized by the pupa and the adult. The broad features of the transfer of larval resources to the pupae and the allocation of larval resources in the adult have been described by studies measuring and ...
Ha Leah Y - - 2012
BACKGROUND: A failure of urine ammonium to increase during acidosis indicates impaired renal acidification, and the urinary ammonium concentration is therefore a useful investigation in determining the cause of a metabolic acidosis. However, urine ammonium measurements are not widely available in routine diagnostic laboratories. This has led to the use ...
Rillahan Cory D - - 2012
Click 'n' chips: Azide and alkyne-bearing sialic acids (purple diamond; see picture) were subjected to high-throughput click chemistry to generate a library of sialic acid analogues. Microarray printing of the library and screening with the siglec family of sialic-acid-binding proteins, led to the identification of high-affinity ligands for siglec-9 and ...
Uerpairojkit Chairoj - - 2012
The objectives of the study are to demonstrate the innervation patterns of the triceps muscles and the most suitable branch of the radial nerve for nerve transfer to restore the motor function of the deltoid muscle in patients with complete C5-C6 root injury. Seventy-nine arms (40 left arms and 39 ...
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