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Results 301 - 350 of 2847
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Martínez G - - 2012
The present work addresses the main bottleneck in the synthesis of magnetic nanoparticles by laser pyrolysis. Since the introduction of laser pyrolysis for the production of nanoparticles nearly three decades ago, this method has been repeatedly presented as a highly promising alternative, on account of two main characteristics: (i) its flexibility, ...
Connor Thomas Richard TR Pathogen Genomics, Wellcome Trust Sanger Institute, Cambridge, - - 2012
The disparity in diversity between unencapsulated (non-typable; NT) and encapsulated, serotypable Haemophilus influenzae (Hi) has been recognized for some time. It has previously been suggested that the wider diversity evidenced within NTHi compared with typable lineages may be due to different rates of recombination within the encapsulated and NT populations. ...
Lind Bonnie K BK Saint Luke's Health System, Boise, ID 83712, USA. - - 2013
Complementary and alternative medicine (CAM) providers are becoming more integrated into the United States health care system. Because patients self-select CAM use, risk adjustment is needed to make the groups more comparable when analyzing utilization. This study examined how the choice of risk adjustment method affects assessment of CAM use ...
Taylor J David - - 2012
The 8-repetition maximum test has the potential to be a feasible, cost-effective method of measuring muscle strength for clinicians. The purpose of this study was to investigate the concurrent validity of the 8-repetition maximum test in the measurement of muscle strength by comparing the 8-repetition maximum test to the gold ...
Woollard David J - - 2012
BACKGROUND: Prostate cancer disseminates to regional lymph nodes, however the molecular mechanisms responsible for lymph node metastasis are poorly understood. The vascular endothelial growth factor (VEGF) ligand and receptor family have been implicated in the growth and spread of prostate cancer via activation of the blood vasculature and lymphatic systems. ...
Leuchte Hanno H - - 2012
Background: Pulmonary hypertension (PH) of various causes leads to a poor prognosis. Pulmonary vasoreactivity testing during right heart catheterization (RHC) has prognostic and therapeutic consequences. Objective: To characterize the acute hemodynamic response to short-term oxygen supplementation (SHOT) in adult PH patients and its impact on prognosis. Methods: After a stable ...
Tabaee Abtin - - 2012
BACKGROUND: The past decade has witnessed the emergence of rhinology as a distinct subspecialty within otolaryngology. A critical evaluation of this process is necessary to define the field and to determine the impact of subspecialization on residency education. METHODS: An Internet-based survey of otolaryngology residency chairmen was performed to query ...
Yoo Woo-Jin - - 2012
A simple and straightforward method for the preparation of indole-3-carboxylic acids was discovered through the direct carboxylation of indoles with atmospheric pressure of carbon dioxide (CO(2)) under basic conditions. The key for the reaction was found to be the use of a large excess of LiO(t)Bu as a base to ...
Shamseldin Hanan E HE Department of Genetics, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi - - 2013
Mendelian phenotypes in humans vary from benign variants to lethal disorders. Embryonic lethal phenotypes that are similar to what has been known for a long time in mice have remained largely unknown because of the difficulty in arriving at a molecular diagnosis. The purpose of this study is to test ...
Benjamin Neelon Sara E - - 2012
OBJECTIVE: The purpose of the present study was to assess the nutritional quality of foods and beverages listed on menus serving children in government-sponsored child-care centres throughout Mexico. DESIGN: For this cross-sectional menu assessment, we compared (i) food groups and portion sizes of foods and beverages on the menus with ...
Kotikam Venubabu - - 2012
The fluorescently labelled short octameric oligothymine sequences of DNA, PNA and PCNA were used in fluorescence quenching studies in conjunction with dispersed graphene oxide. The measurable restoration of their fluorescence by complementary oligodeoxyadenylate was compared. This is the first study aimed at replacing the natural DNA probes with synthetic DNA ...
Donadeu Francesc Xavier - - 2012
Although much progress has been made in the genetic dissection of biological networks involved in follicular/luteal development in the mammalian ovary, the gene regulation mechanisms involved are still poorly understood. Over the last 10 years, miRNAs have emerged as master regulators of tissue growth and differentiation in animals. However, compared ...
Lau Tze Kin - - 2012
Abstract Non-invasive prenatal screening for fetal Down syndrome (NIFTY) by maternal plasma sequencing was performed in 12 subjects with twin pregnancies, including 11 with normal fetuses and 1 with discordant fetal Trisomy 21. For every sample, it was processed, sequenced and reported as soon as it was collected as other ...
Devaraj Sridevi - - 2012
Abstract Background: Metabolic syndrome affects 1 in 3 U.S. adults. The primary target of treatment of patients with metabolic syndrome is therapeutic lifestyle change. Numerous animal trials have reported positive effects of Aloe vera in in vivo models of diabetes, but there is a paucity of controlled clinical trials in patients ...
Judson Robert N RN School of Medical Sciences, University of Aberdeen, Aberdeen, AB25 2ZD, - - 2012
Satellite cells are the resident stem cells of skeletal muscle. Mitotically quiescent in mature muscle, they can be activated to proliferate and generate myoblasts to supply further myonuclei to hypertrophying or regenerating muscle fibres, or self-renew to maintain the resident stem cell pool. Here, we identify the transcriptional co-factor Yap ...
Lin Y - - 2012
Amplification of aurora kinase A (AK-A) overrides the mitotic spindle assembly checkpoint, inducing resistance to taxanes. RNA interference targeting AK-A in human pancreatic cancer cell lines enhanced taxane chemosensitivity. In this study, a novel AK-A inhibitor, CYC3, was investigated in pancreatic cancer cell lines, in combination with paclitaxel. Western blot, ...
Lazzaro Daniel P - - 2012
Many platinum(II) polypyridine complexes are good luminophores, an enigmatic exception being Pt(trpy)Ph(+), where trpy denotes 2,2':6',2″-terpyridine. A new analysis suggests the complex is nonemissive due to (3)SBLCT (sigma-bond-to-ligand charge transfer) character in the lowest energy excited state. Bases for two distinct strategies for inducing emission from aryl derivatives become clear. ...
Singh Balwinder - - 2012
OBJECTIVES: To perform a systematic review and meta-analysis including all the current studies to assess the accuracy of pulmonary embolism rule-out criteria (PERC) in ruling out pulmonary embolism (PE). METHODS: We conducted a comprehensive search of the major databases (Ovid Medline In-Process & Other Non-Indexed Citations, Ovid MEDLINE, Ovid EMBASE, ...
Kazantseva Marina - - 2012
ABSTRACT: INTRODUCTION: Smoking increases the risk of developing rheumatoid arthritis (RA) and affects the severity of established RA. Smoking can impact on Th17 lymphocyte differentiation and function through activation of the aryl hydrocarbon receptor (AHR), a process with implications for the pathogenic mechanisms in RA that involve the cytokine, interleukin ...
Yu Yanwen - - 2012
A new p-phenylenevinylene-linked perylene diimide has been synthesized and self-assembled for the formation of zero-dimensional molecular aggregate structures of nanospheres and vesicles through solvent tuning. The solid-state optical properties induced by a special wavelength laser were studied and the results indicated excellent fluorescent enhancement properties. The emission intensity of these ...
Atar Murat - - 2012
Abstract Objective.The aim of this study was to investigate the effects of acute exercise on the diameter of the spermatic vein, and on the duration of reflux in patients with varicocele. Material and methods. The study included 38 patients with complaints of infertility and scrotal pain between 2009 and 2010. ...
Jalabert D - - 2012
Medium energy ion spectroscopy experiments have been performed on an ensemble of nanowires deposited by molecular beam epitaxy on Si(111), taking advantage of their reduced in-plane mosaicity. In particular, the strain in nanometric GaN insertions embedded in AlN sections deposited on top of GaN nanowires has been determined. The measured ...
Al Aïn Syrina - - 2012
It is a mammalian female strategy to emit odor cues and signals that direct their inexperienced newborns to the nipple, and optimize their initial sucking success and, hence, viability. Here, natural odorous substrates that contribute to nipple grasping were investigated in mice, a species that has not been much scrutinized ...
Sullivan Kevin M - - 2012
OBJECTIVE: Neonates are at high risk for significant morbidity and mortality from medication prescribing errors. Despite general awareness of these risks, mistakes continue to happen. Alerts in computerised physician order entry intended to help prescribers avoid errors have not been effective enough. This improvement project delivered feedback of prescribing errors ...
Bremner Fion D - - 2012
Purpose:To investigate the correlation between measurements of amplitude (A) and peak velocity (V) of constriction in the pupil light reflex of normal subjects, and to determine the effects of stimulus intensity, pupil size and age on this relationship. Methods:The pupil response to a variable intensity 1.0 second light stimulus presented ...
Rashamuse Konanani - - 2012
A shotgun metagenomic library was constructed from termite hindgut symbionts and subsequently screened for esterase activities. A total of 68 recombinant clones conferring esterolytic phenotypes were identified, of which the 14 most active were subcloned and sequenced. The nucleotide lengths of the esterase-encoding open reading frames (ORFs) ranged from 783 ...
Murray Jennifer J Department of Diabetes and Metabolic Diseases Research, Division of Cellular and Molecular Diabetes Research, Beckman Research Institute, City of Hope, Duarte, California 91010, - - 2013
Specialized contractile function and increased mitochondrial number and oxidative capacity are hallmark features of myocyte differentiation. The estrogen-related receptors (ERRs) can regulate mitochondrial biogenesis or mitochondrial enzyme expression in skeletal muscle, suggesting that ERRs may have a role in promoting myogenesis. Therefore, we characterized myogenic programs in primary myocytes isolated ...
Panahi Yunes - - 2012
BACKGROUND: Chronic cutaneous complications such as pruritus are among the very frequent complaints of sulphur mustard (SM)-exposed patients. The present trial investigated the impact of curcumin on serum inflammatory biomarkers and their association with pruritus severity and quality of life (QoL). METHODS: This was a randomized, double-blind trial among 96 ...
Sah Shatrughan P - - 2012
AIMS: DOG1 is a recently described marker of gastrointestinal stromal tumour (GIST) which is considered to be extremely sensitive and, among mesenchymal neoplasms, quite specific for this tumour type. Following the identification of DOG1 immunoreactivity in a uterine leiomyosarcoma, we wished to ascertain how prevalent DOG1 immunoreactivity was in this ...
Gama Sofia - - 2012
New [PtCl(pz*NN)](n+) complexes anchored by pyrazolyl-diamine (pz*NN) ligands incorporating anthracenyl or acridine orange DNA-binding groups have been synthesized so as to obtain compounds that would display synergistic effects between platination and intercalation of DNA. Study of their interaction with supercoiled DNA indicated that the anthracenyl-containing complex L(2) Pt displays a ...
Schrezenmeier Eva - - 2012
Background/Aims: Putative in vitro-in vivo correlations of pharmacokinetic (PK) parameters are regarded as a prerequisite to filter hits derived from high-throughput screening (HTS) approaches for subsequent murine in vivo PK studies. Methods: In this study, we assessed stabilities in rat and human microsomes of 121 compounds from an early, academic ...
Klimek-Piotrowska Wiesława - - 2012
During a routine dissection at the Department of Anatomy, Collegium Medicum, Jagiellonian University, one cadaver was found to have multiple variations of the arteries of the upper limbs. The variations pertained to the course of the brachial artery as well as to its distribution. An unusual formation of the superficial ...
Himanen Risto - - 2012
There are four operating nuclear power plant (NPP) units in Finland. The Teollisuuden Voima (TVO) power company has two 840 MWe BWR units supplied by Asea-Atom at the Olkiluoto site. The Fortum corporation (formerly IVO) has two 500 MWe VVER 440/213 units at the Loviisa site. In addition, a 1600 ...
Lovaas Jenna D JD Cancer Research Center and Department of Medicine, Boston University School of Medicine, Boston, Massachusetts 02118, - - 2013
Matrix metalloproteinase-2 (MMP2) has been shown to play an important role in cancer cell invasion and the expression of MMP2 is associated with the poor prognosis of prostate cancer; however, the mechanism of MMP2 expression is largely unknown. SIRT1 is a nicotinamide adenine dinucleotide-dependent histone deacetylase (class III HDAC) that ...
Martins Clarice - - 2012
Background: Metabolic Syndrome (MS) is highly prevalent among obese children with fatty liver. However, it is well-known that there is a lower prevalence of MS in individuals with higher cardiorespiratory fitness (CRF). Aim: To analyse the association between CRF with features of the MS in obese children that present fat ...
Jin Kai - - 2012
Fungal biocontrol agents have great potential in integrated pest management. However, poor efficacy and sensitivity to various adverse factors have hampered their wide application. In eukaryotic cells, Hog1 kinase plays a critical role in stress responses. In this study, MaHog1 (GenBank accession number EFY85878), encoding a member of the Hog1/Sty1/p38 ...
Wyndaele Jean-Jacques - - 2012
What's known on the subject? and What does the study add? Clean intermittent catheterization (CIC) is considered the method of choice for bladder emptying when neurological or non-neurological causes make normal voiding impossible or incomplete. The outcome is overall good, also in the long-term. There is neither one best technique ...
Szarek Dariusz - - 2012
In this study, scanning electron microscopy (SEM) has been applied for instantaneous assessment of processes occurring at the site of regenerating nerve. The technique proved to be especially useful when an artificial implant should have been observed but have not yet been extensively investigated before for assessment of nerve tissue. ...
Shakibaie Mojtaba - - 2012
Context: In the present investigation, acute and subacute toxicity of the biogenic Se nanoparticles (Se NPs) has been reported. Objective: To characterize the Se NPs produced by a bacterium species and to evaluate their toxicity and impact on clinical chemistry and hematological parameters of NMRI mice. Materials and methods: The ...
Yan Biao - - 2012
MyoD is one of the helix-loop-helix proteins regulating muscle-specific gene expression in tilapia. Tight regulation of MyoD protein level is necessary for the precise regulation of skeletal muscle development. MicroRNAs (miRNAs) are a class of regulatory RNAs that post-transcriptionally regulate gene expression. Increasing evidences have suggested that miRNAs play an ...
Lipke Mark C - - 2012
Hydridosilicate anions ([ArSiH(4) ](-) and [SiH(6) ](2-) ) were stabilized as ligands in diruthenium SiH σ-complexes [{(PhBP(Ph) (3) )Ru}(2) (μ-Cl)(μ-η(3) ,η(3) -H(4) SiAr)] (Ar=2-MeOC(6) H(4) , Mes, Ph) and [{(PhBP(Ph) (3) )Ru}(2) (μ-η(4) ,η(4) -H(6) Si)]. These complexes were formed under mild conditions and characterized by single-crystal X-ray diffraction, NMR ...
Grochala Wojciech - - 2012
Elemental helium is a prototypical noble gas and its atom sets the records for many physicochemical properties. With its two electrons in the closed 1s shell, He is the smallest, the least polarizable, the most difficult to ionize, the hardest (in Pearson's sense) and the most electronegative atom known. Helium ...
Brandmayr Caterina - - 2012
Useful diversity: Quantification of modified tRNA nucleobases in different murine and porcine tissues reveals a tissue-specific overall modification content. The modification content correlates with rates of protein synthesis in vitro, suggesting a direct link between tRNA modification levels and tissue-specific translational efficiency.
Modan-Moses Dalit - - 2012
Background:Multiple studies associate low vitamin D levels with cancer morbidity and mortality. However, few studies measured vitamin D in pediatric patients with malignancy. Our aim was to assess vitamin D status in a large cohort of pediatric cancer patients and define risk factors for deficiency.Methods:Circulating 25-hydroxyvitamin D (25OHD) was measured ...
Yan Jin - - 2012
Introduction.  Monogamous female sexually transmitted infection (STI) patients are at high risk of recurrent STI, but there is no study investigating their risk behaviors. Aim.  We investigated the prevalence of male condom use and associated factors among monogamous STI female patients. Main Outcome Measures.  Independent variables included socio-demographic characteristics, STI ...
Stephenson F Anne FA University College London School of Pharmacy, London WC1N 1AX, UK. - - 2012
The year 2012 marks the 25th anniversary of the discovery of the Cys loop ligand-gated ion channel superfamily of neurotransmitter receptors. This minireview series celebrates this with a series of articles reviewing current information for each of the family members, nicotinic acetylcholine receptors, glycine receptors, GABA(A) receptors, serotonin-3 (5-HT(3)) receptors, ...
Koh Travis L - - 2012
Vertically aligned metal oxide nanostructures (e.g., wires, needles, pillars and trees) of CuO, PdO and NiO were synthesized on several substrates (e.g., Si and ITO (indium tin oxide)) using a high-pressure (∼Torr) microplasma-based growth technique. Organometallic precursors were dissociated in the hollow cathode region of a supersonic plasma jet creating ...
Joo Kisu - - 2012
Although graphene looks attractive to replace indium tin oxide (ITO) in optoelectronic devices, the luminous efficiency of light emitting diodes (LEDs) with graphene transparent conducting electrodes has been limited by degradation in graphene taking place during device fabrication. In this study, it was found that the quality of graphene after ...
Rodriguez L L Center for Motility and Functional Gastrointestinal Disorders, Division of Gastroenterology, Department of Medicine, Children's Hospital Boston, Harvard Medical School, Boston, MA, USA. - - 2013
Antegrade continence enemas (ACE) have been used in the treatment of defecation disorders in children; little is known on their effect on colon motility and the utility of the colon manometry (CM) predicting long-term ACE outcomes. Retrospective review of children with constipation undergoing CM before and after ACE to evaluate ...
Xu Jin J Department of Ophthalmology and Visual Sciences, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI 53705, - - 2012
Fusion of lysosomes with the plasma membrane is a calcium-dependent process that is crucial for membrane repair, limiting pathogen entry and clearing cellular debris. In non-polarized cells, lysosome exocytosis facilitates rapid resealing of torn membranes. Here, we investigate the mechanism of lysosome exocytosis in polarized epithelia, the main barrier between ...
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