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Results 251 - 300 of 2847
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Romejko-Wolniewicz Ewa - - 2012
Abstract Objective: The objective of this study was to compare the effects of two betamethasone dosage regimens on selected parameters in mothers and on the status of the preterm newborn. Methods: The analysis included 121 patients who gave birth by gestational week 35 and within 7 days after the completion ...
Sen Anik - - 2012
Crystal face lift: Barbituric acid is shown to be a new crystal-habit modifier for sodium chloride crystals. Two morphologies of salt crystals can be prepared separately with this new additive. It is of the few additives able to induce rhombic dodecahedron crystals for NaCl, and is required only a trace ...
Lee Ban S - - 2012
OBJECTIVES: To compare survival in older (≥65) and younger (<65) individuals with biliary tract cancer (BTC) and to determine whether treatment efficacy varies according to age. DESIGN: Retrospective cohort study and nested case-control study. SETTING: Tertiary referral center in Korea. PARTICIPANTS: Five hundred thirty-one individuals diagnosed with BTC from 2003 ...
Lowe David A - - 2012
ACADEMIC EMERGENCY MEDICINE 2012; 19:000-000 © 2012 by the Society for Academic Emergency Medicine ABSTRACT: Objectives:  Patient and parent satisfaction are important measures of quality of care. Data are lacking regarding satisfaction with emergency procedures, including laceration repair. The objective was to define the elements of care that are important ...
Mitsui Jun - - 2012
Genetic and phenotypic heterogeneities are considerably high in adult-onset leukoencephalopathy, in which comprehensive mutational analyses of the candidate genes by conventional methods are too laborious. We applied exome sequencing to conduct a comprehensive mutational analysis of genes for autosomal dominant leukoencephalopathies. Genomic DNA samples from four patients of three families ...
Beach Christopher - - 2012
ACADEMIC EMERGENCY MEDICINE 2012; 19:000-000 © 2012 by the Society for Academic Emergency Medicine ABSTRACT: Patient care transitions across specialties involve more complexity than those within the same specialty, yet the unique social and technical features remain underexplored. Further, little consensus exists among researchers and practitioners about strategies to improve ...
Atanasova-Penichon Vessela - - 2012
Fusarium graminearum is the causal agent of Gibberella ear rot and produces trichothecene mycotoxins. Basic questions remain unanswered regarding the kernel stage(s) associated with trichothecene biosynthesis and the kernel metabolites potentially involved in the regulation of trichothecene production in planta. In a two-year field study, F. graminearum growth, trichothecene accumulation, ...
Haisch Christoph - - 2012
A photoacoustic spectrometer for the measurement of aerosol absorption spectra, based on the excitation of a pulsed nanosecond Optical Parametrical Oscillator (OPO), will be introduced. This spectrometer is working at ambient pressure and can be used to detect and characterize different classes of aerosols. The spectrometer features a spectral range ...
Tawadros T - - 2012
High intake of omega-6 polyunsaturated fatty acids (PUFA) has been associated with clinical progression in prostate cancer (CaP). This study investigates the signalling mechanism by which the omega-6 PUFA arachidonic acid (AA) induces prostatic cellular migration to bone marrow stroma. Western blot analysis of the PC-3, PC3-GFP, DU 145 and ...
Piskin Mehmet Mesut - - 2012
Abstract Purpose: In this study, we report our initial experience using microperc for treatment of kidney stones and the implications of the microperc system in bladder stone management. Patients and Methods: Microperc was performed with a 4.85F "all-seeing needle" in 11 patients with stone disease; 9 of the patients had ...
Ogundipe Kolawole Olubunmi - - 2012
BACKGROUND: Emergency department (ED) violence is common and widespread. ED staff receive both verbal and physical abuse, with ED nurses bearing the brunt of this violence. The violence is becoming increasingly common and lethal and many institutions are still improperly prepared to deal with it. METHODS: A questionnaire based survey ...
Caso Jorge J Division of Urologic Surgery, Duke Prostate Center, Department of Surgery, Duke University Medical Center, Durham, North Carolina 27710, - - 2013
No- and low-carbohydrate diets delay tumor growth compared to western diet (WD) in prostate cancer (PCa) xenograft studies. The effect of these diets in concert with androgen deprivation is unknown. A total of 160 male SCID mice were injected with 1× 10(5) LAPC-4 human PCa cells. Of these, 150 mice ...
Pfannenschmidt Ulrike - - 2012
The phosphides REIr(2)P(2) (RE = La-Nd, Sm) and arsenides REIr(2)As(2) (RE = La-Nd) were synthesized by a ceramic route via precursor compounds REIr(2) with phosphorus and arsenic, respectively. Well-shaped single crystals were obtained from lead and bismuth fluxes, respectively. The nine pnictides crystallize with the tetragonal CaBe(2)Ge(2) type structure, space ...
Shill Jessica - - 2012
ACADEMIC EMERGENCY MEDICINE 2012; 19:000-000 © 2012 by the Society for Academic Emergency Medicine ABSTRACT: Objectives:  The objective was to determine, among emergency department (ED) patients, the factors associated with a high level of satisfaction with pain management. Methods:  This was a prospective cohort study in a single ED. Consecutive ...
Browning Travis - - 2012
PURPOSE: To improve timely evaluation and management of newly identified, suspected, gastrointestinal (GI) malignancies discovered on radiologic imaging at a safety-net hospital through direct critical results messaging to surgical specialists. MATERIALS AND METHODS: To address delays in evaluating patients for suspected GI malignancies identified on imaging, an enhanced workflow was ...
Shi Geng-Xian GX Department of Molecular and Cellular Biochemistry, University of Kentucky College of Medicine, Lexington, Kentucky 40536-0509, USA. - - 2012
The cAMP response element (CRE)-binding protein (CREB) is a key regulatory factor of gene transcription, and plays an essential role in development of the central nervous system and for neuroprotection. Multiple signaling pathways have been shown to contribute to the regulation of CREB-dependent transcription, including both ERK and p38 mitogen-activated ...
Chen Jeng-Sheng - - 2012
Study Type--Prognosis (cohort) Level of Evidence 2a. What's known on the subject? and What does the study add? Higher mortality and morbidity rates in men presenting with AUR have been reported in previous studies. This study has comprehensive comparisons of post-TURP complications between patients with and without AUR. Furthermore, it ...
Kostikov Alexey P - - 2012
N-Succinimidyl 3-(di-tert-butyl[(18)F]fluorosilyl)benzoate ([(18)F]SiFB) is a highly reactive prosthetic group for radiolabeling of proteins for use in positron emission tomography (PET). It is similar to N-succinimidyl-4-[(18)F]fluorobenzoate ([(18)F]SFB), the 'gold-standard' prosthetic group for protein (18)F-labeling, but can be synthesized using a much shorter and technically easier procedure. A recently reported simple procedure ...
Marks Sebastian - - 2012
The divalent lanthanide borohydrides [Ln(BH(4))(2)(THF)(2)] (Ln = Eu, Yb) have been prepared in a straightforward approach. The europium compound shows blue luminescence in the solid state, having a quantum yield of 75%. Nonradiative deactivation of C-H and B-H oscillator groups could be excluded in the perdeuterated complex [Eu(BD(4))(2)(d(8)-THF)(2)], which showed ...
Fancello Laura - - 2012
Here, we present the first metagenomic study of viral communities from four perennial ponds (gueltas) located in the central Sahara (Mauritania). Three of the four gueltas (Ilij, Molomhar and Hamdoun) are located at the source of three different wadis belonging to the same hydrologic basin, whereas the fourth (El Berbera) ...
Kraft Andrew W AW The Hope Center for Neurological Disorders, Knight Alzheimer's Disease Research Center, Department of Neurology, Washington University School of Medicine, St. Louis, Missouri 63124, - - 2013
The accumulation of aggregated amyloid-β (Aβ) in amyloid plaques is a neuropathological hallmark of Alzheimer's disease (AD). Reactive astrocytes are intimately associated with amyloid plaques; however, their role in AD pathogenesis is unclear. We deleted the genes encoding two intermediate filament proteins required for astrocyte activation-glial fibrillary acid protein (Gfap) ...
Dowd W Wesley - - 2012
Coping with environmental stress may involve combinations of behavioral and physiological responses. We examined potential interactions between adult mussels' simple behavioral repertoire - opening/closing of the shell valves - and thermal stress physiology in common-gardened individuals of three Mytilus congeners found on the West Coast of North America, two of ...
Neat Michael J - - 2012
Fluorescence in situ hybridisation (FISH) analysis is now widely employed in the diagnosis and risk stratification of a wide range of malignant diseases. While this technique is used successfully with formalin-fixed paraffin-embedded (FFPE) sections from numerous tissue types, FISH analysis of FFPE tissue sections from trephine biopsy specimens has been ...
Biegus Jan - - 2012
INTRODUCTION Acute heart failure (AHF) is associated with multiorgan dysfunction which unfavorably affects prognosis.  OBJECTIVES We investigated the prevalence, determinants and prognostic consequences of abnormal liver function tests (LFTs) in AHF population.  PATIENTS AND METHODS Retrospective analysis of AHF patients with LFTs (serum bilirubin, AST [Aspartate aminotransferase], ALT [Alanine Aminotransferase] and albumin) on ...
Larrouy-Maumus Gérald G CNRS, Institut de Pharmacologie et de Biologie Structurale, Département Mécanismes Moléculaires des Infections Mycobactériennes, F-31077 Toulouse, - - 2012
The biosynthesis of the major cell envelope glycoconjugates of Mycobacterium tuberculosis is topologically split across the plasma membrane, yet nothing is known of the transporters required for the translocation of lipid-linked sugar donors and oligosaccharide intermediates from the cytoplasmic to the periplasmic side of the membrane in mycobacteria. One of ...
Charpentier P A - - 2012
Grafting from polymerization was used to synthesize nano-titania/polyurethane (nTiO(2)/polyurethane) composite coatings, where nTiO(2) was chemically attached to the backbone of the polyurethane polymer matrix with a bifunctional monomer, 2,2-bis(hydroxymethyl) propionic acid (DMPA). This bifunctional monomer can coordinate to nTiO(2) through an available -COOH group, with two available hydroxyl groups that ...
Takenaka Mizuki - - 2012
RNA editing is an RNA maturation process that changes the nucleotide present at particular positions (editing sites) in specific RNAs; in plant organelles, the most common nucleotide change is from cytidine (C) to uridine (U). In a mutant suspected of affecting RNA editing, all known editing sites have to be ...
Blease Charlotte Rosalind - - 2012
Major depressive disorder is not only the most widespread mental disorder in the world, it is a disorder on the rise. In cases of particularly severe forms of depression, when all other treatment options have failed, the use of electroconvulsive therapy (ECT) is a recommended treatment option for patients. ECT ...
Su Wenhui W The Mary M. Wohlford Laboratory for Male Contraceptive Research, Center for Biomedical Research, Population Council, New York, NY 10065, - - 2012
During spermatogenesis, spermiogenesis that releases sperm into the tubule lumen and restructuring of the blood-testis barrier (BTB) that accommodates the transit of preleptotene spermatocytes take place simultaneously, but at the opposite ends of the seminiferous epithelium. These events are tightly regulated and coordinated; however, neither the underlying mechanism(s) nor the ...
Lam Matthew - - 2012
BACKGROUND: Chronic rhinosinusitis (CRS) is a heterogeneous disease defined by epithelial inflammation. The link between measures of traditional disease severity and markers of epithelial inflammation is poorly understood as prior research has focused on presence of polyps or degree of eosinophilia. The expression of 3 epithelial derived cytokines implicated in ...
Valencia-Hernández Ignacio - - 2012
The present study investigated the hypothesis that the duration of ovarian hormone deprivation before reintroduction of oestrogen affects the role of oestrogen as a mediator of the contractile function of α(1)-adrenergic receptors. Rats underwent ovariectomy (OVX) or were sham-operated, and the OVX rats were treated with vehicle (corn oil) or ...
Tang Wenjian - - 2012
In chromophore-containing cyclobutane pyrimidine dimer (CPD) model systems, solvent effects on the splitting efficiency may depend on the length of the linker, the molecular conformation, and the oxidation potential of the donor. To further explore the relationship between chromophore structure and splitting efficiency, we prepared a series of substituted indole-T<>T ...
van Hasselt F M - - 2012
Therapeutic drug monitoring to optimize blood plasma concentrations is advised for certain psychiatric drugs. The current standard is to change the dose based on the blood plasma concentration. We present an overview that blood plasma concentrations can also be influenced by adding co-medication based on pharmacokinetic knowledge.We performed a systematic ...
Hedberg Magnus - - 2012
Abstract Objectives: Stroke following cardiac surgery may occur in association to surgery (early) or postoperatively (delayed). The hemispheric distribution of lesions may provide information about embolic routes, which was analyzed here. Design: In 10 809 patients undergoing cardiac surgery, early (n=223) and delayed stroke (n=116) were explored. Symptoms and computed-tomography ...
Tschanz Joann T JT Department of Psychology, Utah State University, Logan, UT, - - 2013
Stressful life events (SLE) have been associated with increased dementia risk, but their association with cognitive decline has been inconsistent. In a longitudinal population-based study of older individuals, we examined the association between SLE and cognitive decline, and the role of potential effect modifiers. A total of 2665 non-demented participants ...
Hoffman Michele T - - 2012
Huanglongbing (HLB) is one of the most destructive diseases of citrus worldwide. The three known causal agents of HLB are species of α-proteobacteria, 'Candidatus Liberibacter asiaticus' (Las), 'Ca. Liberibacter africanus' and 'Ca. Liberibacter americanus'. Previous studies have found distinct variations in temperature sensitivity and tolerance among these species. Here we ...
Seppala Jonathan E - - 2012
We present a spatially resolved approach for the solvent vapor annealing (SVA) of block copolymer thin films that permits the facile and relatively rapid manipulation of nanoscale ordering and nanostructure orientation. In our method, a localized (point) SVA zone is created through the use of a vapor delivery nozzle. This ...
Braun Donald P - - 2012
Abstract Objectives: Use of naturopathic and nutritional supplements (NNS) with antioxidant activity is controversial in patients receiving radiation therapy. The effects of concomitant use of NNS with antioxidant activity during radiation therapy for prostate cancer were investigated in terms of clinical tumor responsiveness, kinetics, and durability. Materials and methods: A ...
Cao Chuanding - - 2012
ABSTRACT: INTRODUCTION: 3% Sodium Chloride (NaCl) treatment has been shown to reduce brain edema and inhibited brain aquaporin 4 (AQP4) expression in bacterial meningitis induced by Escherichia coli. Lipopolysaccharide (LPS) is the main pathogenic component of Escherichia coli. We aimed to explore the effect of 3% NaCl in mouse brain ...
Desmettre Thibaut - - 2012
ABSTRACT: INTRODUCTION: Prothrombin Complex Concentrate (PCC) is a key treatment in the management of bleeding related to Vitamin K antagonists (VKA). This study aimed to evaluate prospectively PCC use in patients with VKA-related bleeding in view of the current French guidelines edited in 2008. METHODS: All consecutive patients with VKA-related ...
Louw Adriaan A International Spine Pain Institute and Neuro Orthopaedic Institute, Story City, IA, - - 2013
Evaluate content and educational delivery methods of preoperative education in total joint arthroplasties of the hip and knee (THA and TKA) addressing postoperative pain. Systematic searches conducted on Biomed Central, BMJ.com, CINAHL, the Cochrane Library, NLM Central Gateway, OVID, ProQuest (Digital Dissertations), PsycInfo, PubMed/Medline, ScienceDirect, and Web of Science. Secondary ...
Herrmann Stephen D - - 2012
BACKGROUND: There is little consensus on how many hours of accelerometer wear time is needed to reflect a usual day. This study identifies the bias in daily physical activity (PA) estimates caused by accelerometer wear time. METHODS: 124 adults (age = 41 ± 11 years; BMI = 27 ± 7 ...
Smith Wayne S - - 2012
The human eye continuously forms images of our 3D environment using a finite and dynamically changing depth of focus. Since different objects in our environment reside at different depth planes, the resulting retinal images consist of both focused and spatially blurred objects concurrently. Here, we wanted to measure what effect ...
Krasowska MaƂgorzata - - 2012
The electronic and geometric structure of various substituted borylenes BR (where R = H, F, Cl, Br, CH(3), Ph, NH(2), NHMe, and NMe(2)) in their lowest singlet and triplet electronic states was investigated by computational means using hybrid density functional (B3LYP) and second-order Møller-Plesset perturbation theories combined with 6-311+G** and ...
Choi Soo Young - - 2012
Background: Protein translation and translocation at the rough endoplasmic reticulum (RER) are the first steps in the secretory pathway. The translocon through which newly made proteins are translocated into or across the RER membrane consists of three main subunits: Sec61α, -β, and -γ. Sec61β facilitates translocation, and we and others ...
Siew Edward D ED Department of Medicine, Division of Nephrology, Vanderbilt University Medical Center, 116121st Avenue South, Nashville, TN 37232-2372, USA. - - 2013
Baseline creatinine (BCr) is frequently missing in AKI studies. Common surrogate estimates can misclassify AKI and adversely affect the study of related outcomes. This study examined whether multiple imputation improved accuracy of estimating missing BCr beyond current recommendations to apply assumed estimated GFR (eGFR) of 75 ml/min per 1.73 m(2) ...
Isobe H - - 2012
Full geometry optimizations of several inorganic model clusters, CaMn(4)O(4)XYZ(H(2)O)(2) (X, Y, Z = H(2)O, OH(-) or O(2-)), by the use of the B3LYP hybrid density functional theory (DFT) have been performed to illuminate plausible molecular structures of the catalytic site for water oxidation in the S(0), S(1), S(2) and S(3) ...
Busson Mickaël P - - 2012
An aureate dye: Confined electromagnetic fields in DNA-templated gold nanoparticle dimers were tuned to engineer the fluorescence properties of organic dyes in water. Purified suspensions of hybrid metal-organic chromophores featured unprecedented photophysical properties, such as a short lifetime and low quantum yield but high brightness.
Therrell Bradford L - - 2012
Purpose: We provide background information/education for national recommendations to include initial newborn screening dried bloodspot serial numbers in electronic birth registrations. Mutual data linking would provide quality checks for each data source, determinations of percentages of newborns screened, and identification of locations where screening is lacking.Methods: State newborn screening dried ...
Asthana Jayant J Department of Biosciences and Bioengineering, Indian Institute of Technology Bombay, Mumbai 400076, - - 2012
Dynein Light Chain 1 (LC8) has been shown to pull down tubulin subunits, suggesting that it interacts with microtubules. LC8 decorates microtubules in vitro and in Drosophila embryos, promotes microtubule assembly, and stabilizes microtubules both in vitro and in tissue-cultured cells. LC8 stabilizes microtubules. Data provide the first evidence of ...
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