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Hwang Jin Taek - - 2012
Context: Resveratrol (3,5,4'-trihydroxystilbene) is a phytoalexin synthesized by plants, most notably grapes, against microbial invasion or ultraviolet stimulation, and is known to exert antioxidant, anticancer, and antiobesity effects. Objective: This study was conducted to find resveratrol derivatives with higher anti-obesity activity compared to resveratrol and to verify their mechanism of ...
Rassart Jessica - - 2012
This study investigated how the Big Five personality traits were related to quality of life and perceived health in adolescents with congenital heart disease (CHD). Adolescents with CHD were selected from the database of paediatric and congenital cardiology of the University Hospitals Leuven. A total of 366 adolescents (15-20 years) ...
Tausz-Posch Sabine - - 2012
This study evaluates whether the target breeding trait of superior leaf level transpiration efficiency is still appropriate under increasing carbon dioxide levels of a future climate using a semi-arid cropping system as a model. Specifically, we investigated whether physiological traits governing leaf level transpiration efficiency, such as net assimilation rates ...
Niiyama Nanako - - 2012
Metallic copper has been shown significantly to reduce methicillin-resistant Staphylococcus aureus (MRSA) contamination of the ambient surroundings of the beds of MRSA-carrying patients in dermatology wards. The aim of this study was to determine whether a bed sheet made of copper-coated film will reduce the spread of MRSA contamination in ...
Forier Katrien - - 2012
Aim: The aim of this study was to evaluate the effect of the surface functionalization of model nanoparticles on their mobility in bacterial biofilms and cystic fibrosis sputum. Materials & methods: With single-particle tracking microscopy, the mobility of 0.1 and 0.2 µm fluorescent polyethylene glycol (PEG) modified, carboxylate- and N,N-dimethylethylenediamine-modified ...
Kolluru Lakshmi Prasanna - - 2012
Background: Generally, chemotherapeutic drugs attack on both normal and tumor cells non-specifically causing life threatening side effects, necessitating targeted drug delivery to tumors. Purpose: The purpose of this study is to formulate albumin-based nanoparticles for tumor targeted drug delivery and noninvasive diagnosis. Methods: Albumin based nanoparticles (NPs) were developed as ...
Shen Laifa - - 2012
Self-supported Li(4) Ti(5) O(12) nanowire arrays with high conductivity architectures are designed and fabricated for application in a Li-ion battery. The Li(4) Ti(5) O(12) nanowire arrays grow directly on Ti foil by a facile solution-based method, further enhancing Li-ion storage properties by creating Ti(3+) sites through hydrogenation. This configuration ensures ...
Stieglitz Thomas - - 2012
Abstract Phantom limb pain (PLP) is a chronic condition that develops in the majority of amputees. The underlying mechanisms are not completely understood, and thus, no treatment is fully effective. Based on recent studies, we hypothesize that electrical stimulation of afferent nerves might alleviate PLP by giving sensory input to ...
Scott Lesley J - - 2012
Pneumococcal polysaccharide conjugate vaccine (13-valent, adsorbed) (PCV13; Prevenar 13(®); Prevnar 13(®)) is approved in adults aged ≥50 years (focus of review) and in children aged 6 weeks to 5 years for protection against pneumococcal diseases caused by Streptococcus pneumoniae in numerous countries worldwide, including the US and those in the EU; specific indications ...
Hu Benlin - - 2012
The uniformity of operating parameters in organic nonvolatile memory (ONVM) devices is very important to avoid false programming and error readout problems. In the present work, we fabricated an organic resistive switching memory based on protonic acid doped-polyazomethine (PA-TsOH), which demonstrates an excellent operative uniformity and multilevel storage capability. The ...
Kretzschmar Ruben - - 2012
Blast furnace sludge (BFS), an industrial waste generated in pig iron production, typically contains high contents of iron and various trace metals of environmental concern, including Zn, Pb, and Cd. The chemical speciation of these metals in BFS is largely unknown. Here, we used a combination of synchrotron X-ray diffraction, ...
Lalmi B - - 2012
A new table top technique is used to simultaneously analyze the local morphology of crystalline surfaces as well as the misalignment of large scale domains at the topmost surface layer. The approach is based on fast atom diffraction at grazing incidence (GIFAD); the diffraction pattern yields the structural characteristics and ...
Sellu D H - - 2012
BACKGROUND: In order to minimise the risk of blood transfusion errors, all healthcare professionals who participate in the transfusion process are required to be assessed as competent. New and innovative methods of training and competency assessment are required to improve the training process. AIM/OBJECTIVE: The aim of this study was ...
Green Patrick A - - 2012
Within the nasal cavity of mammals is a complex scaffold of paper-thin bones that function in respiration and olfaction. Known as turbinals, the bones greatly enlarge the surface area available for conditioning inspired air, reducing water loss, and improving olfaction. Given their functional significance, the relative development of turbinal bones ...
Kraigsley Alison M - - 2012
Biofilm-material interactions are increasingly recognized as critical to success of some materials/devices and failure of others. We use a model system of dental monomers, salivary pellicles, and oral biofilms to demonstrate for the first time that degree of conversion of cross-linked dimethacrylate polymers alters biofilm metabolic activity. This response is ...
Baer Matthias - - 2012
The purpose of this study was to develop and evaluate the hybrid scatter correction algorithm (HSC) for CT imaging. Therefore, two established ways to perform scatter correction, i.e. physical scatter correction based on Monte Carlo simulations and a convolution-based scatter correction algorithm, were combined in order to perform an object-dependent, ...
Cragg Gordon M - - 2012
Covering: 1955 to 2012The discovery and development of novel, biologically active agents from natural sources, whether they be drugs, agrochemicals or other bioactive entities, involve a high level of interdisciplinary as well as international collaboration. Such collaboration, particularly at the international level, requires the careful negotiation of collaborative agreements protecting ...
Gu Zhengyi - - 2012
A sensitive and specific high-performance liquid chromatography-electrospray ionization-tandem mass spectrometry (HPLC-ESI-MS/MS) method was developed and validated for determination of rupestonic acid in rat plasma. Protein precipitation method was used to extract rupestonic acid and the internal standard (IS) warfarin sodium from rats plasma. The chromatographic separation was performed on an ...
Cao Lingling - - 2012
Defects in the desmin gene have been identified in patients with cardiac and skeletal myopathy characterized by sarcoplasmic accumulation of desmin-positive deposits and electron dense granulofilamentous aggregates. We describe a desminopathy family with unusual clinical features of complete atrioventricular block and mild myopathy. The atrioventricular block can be found in ...
Nolan Michael - - 2012
In this paper we present the results of empirical potential and density functional theory (DFT) studies of models of interfaces between amorphous silicon (a-Si) or hydrogenated amorphous Si (a-Si:H) and crystalline Si (c-Si) on three unreconstructed silicon surfaces, namely (100), (110) and (111). In preparing models of a-Si on c-Si, ...
Sánchez Juana - - 2012
SCOPE: This study investigates the lasting effects of maternal supplementation with different fat sources during pregnancy and lactation on feeding behavior and energy homeostasis of their offspring, and its relation to hypothetical effects in the development of main central structures involved in leptin signaling. METHODS AND RESULTS: Offspring of dams ...
Drake M - - 2012
Cloacal swabs and caecal contents sampled from 58 cane toads (Bufo marinus) in St George's parish, Grenada, during a 7-month period in 2011 were examined by an enrichment and selective culture method for presence of Salmonella spp. Twenty-four (41%) toads were positive for Salmonella spp. of which eight were Salmonella ...
Fernandes C - - 2012
BACKGROUND: Citrobacter koseri has not been associated to infection caused by blood component transfusions. CASE REPORT: A 46-year-old female patient presented sudden chills, dyspnoea, and tachycardia during a transfusion from a unit of packed red blood cells. Citrobacter koseri was isolated in the two sample collected from the patient and ...
Taylor Stephanie M - - 2012
A combination of complementary cluster ligands results in the formation of a new calixarene-supported ferromagnetic [Mn(5)] cage that displays the characteristic bonding modes of each support.
Prati Gabriele - - 2012
The aim of the present study was to examine the comprehension of gesture in a situation in which the communicator cannot (or can only with difficulty) use verbal communication. Based on theoretical considerations, we expected to obtain higher semantic comprehension for emblems (gestures with a direct verbal definition or translation ...
Benda Christina - - 2012
Traditionally, clinicians and researchers have relied on a skin biopsy or blood extraction as relatively accessible supplies for in vitro cell expansion and biological studies. Perhaps surprisingly, limited attention has been given to a totally noninvasive source, urine, which eliminates the discomfort associated with other procedures. This may arise from ...
van den Ende Joost A - - 2012
We study the effects of temperature and sliding velocity on superlubricity in numerical simulations of the Frenkel-Kontorova model. We show that resonant excitations of the phonons in an incommensurate sliding body lead to an effective friction and to thermal equilibrium with energy distributed over the internal degrees of freedom. For ...
Dalmay C - - 2012
The biological mechanisms induced by the application of nanosecond pulsed electric fields (nsPEFs: high electrical field amplitude during very short duration) on cells remain partly misunderstood. In this context, there is an increasing need for tools that allow the delivering of such pulses with the possibility to monitor their effects ...
Wong Hoi Shan - - 2012
Context: Earlier findings demonstrated that pretreatment of Herba Cistanches [the dried whole plant of Cistanche deserticola Y.C. Ma (Orobanchaceae)], a "Yang-invigorating" Chinese tonic herb, stimulated the ATP-generation capacity (ATP-GC) in mitochondria isolated from rat heart ex vivo. The enhancement of mitochondrial ATP-GC by Herba Cistanches was associated with induction of ...
Gómez-Pereira Paola R - - 2012
Flow cytometric sorting, based on cellular optical properties and macromolecule content, has been successfully employed to taxonomically affiliate bacterioplankton. However, this approach has not been much used for eukaryotic plankton. To redress this imbalance we identified a conspicuous group of red autofluorescent picoplankton in surface waters of the South Atlantic ...
Ypma P F - - 2012
BACKGROUND: The reported percentage of haemato-oncological patients experiencing bleeding complications is highly variable, ranging from 5 to 70%, posing a major problem for comparison of clinical platelet transfusion trials using bleeding complications as a primary endpoint. In a pilot study we assessed the impact of the design of scoring of ...
Aarvold A - - 2012
Tissue engineering offers enormous potential for bone regeneration. Despite extensive in vitro and in vivo work, few strategies translate into clinical practice. This paper describes the combination of skeletal stem cells (SSCs) and impaction bone grafting (IBG) for the treatment of patients with bone defects associated with avascular necrosis of ...
Ray Valerie A - - 2012
Biofilm formation by Vibrio fischeri is a complex process involving multiple regulators, including the sensor kinase (SK) RscS and the response regulator (RR) SypG, which control the symbiosis polysaccharide (syp) locus. To identify other regulators of biofilm formation in V. fischeri, we screened a transposon library for mutants defective in wrinkled ...
Dao Kinh-Luan D - - 2012
Abstract: The estrogen receptor (ER) is a potentially useful biological target for the diagnosis and therapy in hormonally responsive human breast cancer. This protein is often over expressed both on the membrane and nuclear compartment of breast cancer cells and provides a mechanism for both localization and therapy. Over the ...
Girmenia Corrado - - 2012
In the attempt to establish key therapy definitions and provide shared approaches to invasive fungal diseases in neutropenic patients, trials of empiric, preeemptive and targeted antifungal therapy (EAT, PAT and TAT) were reviewed, and a Consensus Development Conference Project was convened. The Expert-Panel concurred that all antifungal treatments, including EAT, ...
Stübig Timo - - 2012
Thoracic injuries are common in vehicle crashes, but only a few studies thus far have analysed the relationship between injury characteristics and collision details and discussed the possible implications for future vehicle design and prevention. In this study, the crash details were prospectively collected at the scene of injury between ...
Fukami Kei - - 2012
Collagenofibrotic glomerulopathy is a very rare glomerular disease characterized by the deposition of Type III collagen fibrils within the subendothelial and mesangial areas, and by elevated serum levels of pro-collagen Type III peptide. We reported here an elderly patient representing the first case of collagenofibrotic glomerulopathy with a "full-house" pattern ...
Douglas Tel - - 2012
Interest is growing in the use of hydrogels as bone tissue-engineering (TE) scaffolds due to advantages such as injectability and ease of incorporation of active substances such as enzymes. Hydrogels consisting of gellan gum (GG), an inexpensive calcium-crosslinkable polysaccharide, have been applied in cartilage TE. To improve GG suitability as ...
Miyazaki Ryo - - 2012
Aim:  Although previous studies have shown that consumption of green tea catechins (GTC) and walking might prevent development of cardiovascular disease (CVD), the effects of GTC supplementation on CVD risk in active older people are unknown. Methods:  A total of 52 older adults (male/female 20/32, mean age 69.1 ± 5.9 years) participating ...
Yu Junping - - 2012
The effects of two C(60) derivatives: C(60)[C(COOH)(2)](3) and C(60)(NH(2))(x)(OH)(y), have been investigated on the bioluminescence of humanized Gaussia luciferase (hGluc) for the first time. Utilizing the dual properties of carboxyl C(60) with luminescence quenching and free radicals scavenging, a novel BRET system was constructed for protease detection with high sensitivity.
Melzer Michael - - 2012
The first highly stretchable and sensitive spin valve sensor on elastomeric membranes are demonstrated. The sensor elements exhibit stable GMR behavior up to tensile strains of 29% in in situ stretching experiments and show no fatigue over 500 loading cycles. This remarkable stretchability is achieved by a predetermined periodic fracture ...
Seidu-Larry Salifu - - 2012
A propargyl containing guanosine phosphoramidite was synthesized and incorporated into siRNA, enabling click-ligation with an azido fluorophore onto the nucleobase sugar edge. Duplex stability was not affected by labeling at this new site, which allowed deconvolution of the effects of label, structure and attachment site on RNAi activity.
Hong Sungmin - - 2012
We report the first comprehensive and reliable time series for As, Mo, Sb, and Tl in the snowpack from Dome Fuji in the central East Antarctic Plateau. Our results show significant enrichment of these elements due to either anthropogenic activities or large volcanic eruptions during the past 50 years. With ...
Dar Sabzar Ahmad - - 2012
Context: Medicinal plants are a largely unexplored source of drug repository. Urtica dioica L. (Urticaceae) is used in traditional medicine to treat diverse conditions. Objective: The present study describes the antidiabetic, antiinflammatory, antibacterial activity, and toxicological studies of Urtica dioica. Materials and methods: U. dioica leaves were subjected to solvent ...
Legrand C - - 2012
The displacement effect of cylindrical ionization chambers is taken into account either by an effective point of measurement (EPOM) or, alternatively, by using a displacement correction factor. The dependence of these effects on water was examined as a function of the cavity radius for (60)Co gamma radiation in a previous ...
Shepherd C - - 2012
PI3 K, mTOR and NOTCH pathways are frequently dysregulated in T-ALL. Blockade of PI3 K and mTOR with the dual inhibitor PI-103 decreased proliferation in 15 T-ALL cell lines tested, inducing cell death in 3. Combined PI3K/mTOR/NOTCH inhibition (with a gamma-secretase inhibitor (GSI)) led to enhanced cell-cycle arrest and to subsequent cell ...
Nadeem Shahid - - 2012
Denitrifying bacteria have variable ability to perform efficient and balanced denitrification during oxygen depletion. NO is often assumed to exert a positive feedback in the transcription of denitrification genes, since NO-dependent activators have been identified. The regulatory network of denitrification is complex, however, and the significance of NO signalling needs ...
Radhakumary Changerath - - 2012
This article reports a simple dipping method for the detection of cyanide ions in water and biological samples, such as blood, using chitosan-gold nanoparticle (CH-Au NP) composite films prepared using CH-Au NP colloids. Here, gold nanoparticles were generated by heating (to ∼80 °C) a solution of chitosan and gold chloride, ...
Benton David - - 2012
The criteria used to establish dietary reference values are discussed and it is suggested that the too often the "need" they aim to satisfy is at the best vaguely specified. The proposition is considered that if we aim to establish optimal nutrition we will gain from considering psychological in addition ...
Liu Guo-Min - - 2012
The conventional lumbar separation was performed by removing soft tissue, subsidiary structures and leaving only the vertebral body. The vertebral body was cut into two halves along the median sagittal plane, keeping the upper and lower end plates of each half, which were subsequently used for biomechanical, morphological and density ...
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