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Results 601 - 650 of 2845
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Wang Haifang - - 2012
A diverse array of carbon nanomaterials (NMs), including fullerene, carbon nanotubes (CNTs), graphene, nanodiamonds, and carbon nanoparticles, have been discovered and widely applied in a variety of industries. Carbon NMs have been detected in the environment and have a strong possibility of entering the human body. The safety of carbon ...
Rybakowski J K - - 2012
We present the case of a male patient with a family history of both bipolar disorder (BD) and Wilson's disease (WD). Wilson's disease was diagnosed for this patient in 2008, at the age of 28 years, and shortly thereafter his bipolar illness began with depressive episodes. The patient has been ...
Morgan Kevin - - 2012
OBJECTIVES: To evaluate the effectiveness of a self-help cognitive behavioral intervention in improving sleep quality in older adults reporting insomnia symptoms associated with chronic disease. DESIGN: A pragmatic two-arm randomized controlled trial comparing supported self-help with treatment as usual (TAU). SETTING: Primary care. PARTICIPANTS: One hundred ninety-three self-referred individuals aged ...
Braun Donald P - - 2012
Abstract Objectives: Use of naturopathic and nutritional supplements (NNS) with antioxidant activity is controversial in patients receiving radiation therapy. The effects of concomitant use of NNS with antioxidant activity during radiation therapy for prostate cancer were investigated in terms of clinical tumor responsiveness, kinetics, and durability. Materials and methods: A ...
Louw Adriaan - - 2012
Objective Evaluate content and educational delivery methods of preoperative education in total joint arthroplasties of the hip and knee (THA and TKA) addressing postoperative pain. Data sources: Systematic searches conducted on Biomed Central, BMJ.com, CINAHL, the Cochrane Library, NLM Central Gateway, OVID, ProQuest (Digital Dissertations), PsycInfo, PubMed/Medline, ScienceDirect, and Web ...
Herrmann Stephen D - - 2012
BACKGROUND: There is little consensus on how many hours of accelerometer wear time is needed to reflect a usual day. This study identifies the bias in daily physical activity (PA) estimates caused by accelerometer wear time. METHODS: 124 adults (age = 41 ± 11 years; BMI = 27 ± 7 ...
Smith Wayne S - - 2012
The human eye continuously forms images of our 3D environment using a finite and dynamically changing depth of focus. Since different objects in our environment reside at different depth planes, the resulting retinal images consist of both focused and spatially blurred objects concurrently. Here, we wanted to measure what effect ...
Krasowska Małgorzata - - 2012
The electronic and geometric structure of various substituted borylenes BR (where R = H, F, Cl, Br, CH(3), Ph, NH(2), NHMe, and NMe(2)) in their lowest singlet and triplet electronic states was investigated by computational means using hybrid density functional (B3LYP) and second-order Møller-Plesset perturbation theories combined with 6-311+G** and ...
Choi Soo Young - - 2012
Background: Protein translation and translocation at the rough endoplasmic reticulum (RER) are the first steps in the secretory pathway. The translocon through which newly made proteins are translocated into or across the RER membrane consists of three main subunits: Sec61α, -β, and -γ. Sec61β facilitates translocation, and we and others ...
Isobe H - - 2012
Full geometry optimizations of several inorganic model clusters, CaMn(4)O(4)XYZ(H(2)O)(2) (X, Y, Z = H(2)O, OH(-) or O(2-)), by the use of the B3LYP hybrid density functional theory (DFT) have been performed to illuminate plausible molecular structures of the catalytic site for water oxidation in the S(0), S(1), S(2) and S(3) ...
Busson Mickaël P - - 2012
An aureate dye: Confined electromagnetic fields in DNA-templated gold nanoparticle dimers were tuned to engineer the fluorescence properties of organic dyes in water. Purified suspensions of hybrid metal-organic chromophores featured unprecedented photophysical properties, such as a short lifetime and low quantum yield but high brightness.
Therrell Bradford L - - 2012
Purpose: We provide background information/education for national recommendations to include initial newborn screening dried bloodspot serial numbers in electronic birth registrations. Mutual data linking would provide quality checks for each data source, determinations of percentages of newborns screened, and identification of locations where screening is lacking.Methods: State newborn screening dried ...
Lee Chung Gun - - 2012
PURPOSE: Suicide is the leading cause of death among Korean adolescents. This study investigates the cross-sectional relations of physical activity with suicidal ideation and attempts in adolescents, simultaneously considering previously reported risk factors of suicide such as depression, stress, and body image. METHODS: This study utilized the 2007 Korea Youth ...
O'Leary Kevin J - - 2012
BACKGROUND: Research supports medical record review using screening triggers as the optimal method to detect hospital adverse events (AE), yet the method is labour-intensive. METHOD: This study compared a traditional trigger tool with an enterprise data warehouse (EDW) based screening method to detect AEs. We created 51 automated queries based ...
Choritz Lars - - 2012
Purpose: Endothelin-1 (ET-1) has been found in elevated concentrations in the aqueous humor of glaucoma patients. Indirect evidence from animal studies suggests that ET-1 might directly influence intraocular pressure (IOP). The aim of this study was to determine whether ET-1 concentrations in aqueous humor of cataract and glaucoma patients correlate ...
Stodulski Maciej - - 2012
Inspired by nature: Self-assembled peptide nanoparticles have been designed that accelerate ester hydrolysis (see picture; Cbz=carbobenzyloxy, NP=p-NO(2) -C(6) H(4) ). The concerted interplay of the multivalent surface with the catalytically active peptide and the substrate at the same time combines several aspects decisive for the catalyst's efficiency, a property characteristic ...
Sato Hisako - - 2012
Mononuclear and dinuclear ruthenium(iii) complexes with bis-β-diketonato ligands (denoted by [Ru(acac)(2)(L-LH)] and [Ru(acac)(2)(L-L)Ru(acac)(2)], respectively) were synthesized, where acac, L-LH(-) and L-L(2-) denote acetylacetonato, monoprotonated and unprotonated bis-β-diketonato ligands, respectively. The following three ligands were used as the bis-β-diketonato ligand (L-L(2-)): 1,2-diacetyl-1,2-dibenzoylethanato (denoted by dabe(2-)), 1,2-diacetyl-1,2-bis(3-methylbutanoyl)ethanato (baet(2-)) and 1,2-diacetyl-1,2-dipropanoylethanato (dpe(2-)). For ...
Dudenko Dmytro - - 2012
To tilt or not to tilt: The crystal structure for bulk P3HT (phase I) was determined by "multi-technique crystallography", which combines X-ray diffraction, solid-state NMR spectroscopy, and DFT calculations. The results showed that this semiconducting polymer crystallizes in the monoclinic space group P2(1) /c with nontilted π-stacks at a distance ...
McGrew Genette I - - 2012
Ligand in a haystack: The first catalytic asymmetric cross-coupling of benzyllithiums α to tertiary amines using [Cr(CO)(3) ] activation of benzylic C sp 3H bonds is described. The stabilized organolithium undergoes Pd-catalyzed coupling with aryl triflates (ArOTf) by a novel dynamic kinetic resolution to yield enantioenriched diarylmethylamines. The chiral ligand for this ...
Rodrigues Nuno - - 2012
Bull rays (Pteromylaeus bovinus) and Dolphinfish (Coryphaena hippurus and Coryphaena equiselis) were collected in Olhão (south of Portugal). These animals hosted multiple parasites, namely Caligus spp., and underwent a variety of treatments to remove them. Of all treatments tested, hydrogen peroxide showed the best results, although only concentrations above 100 ...
Zhu Shuyun - - 2012
Proteases play a central role in several widespread diseases. Thus, there is a great need for the fast and sensitive detection of various proteolytic enzymes. Herein, we have developed a carbon nanotube (CNT)-based protease biosensing platform that uses peptides as a fluorescence probe for the first time. Single-walled carbon nanohorns ...
Mlynarska Agnieszka - - 2012
Background:  Whether the functional status of the heart can influence the coronary venous system itself has not yet been examined. In order to answer this question, we used multislice computed tomography (CT) imaging. Purpose:  To answer the question of whether the heart failure (HF) is associated with significant anatomical changes ...
Charpentier P A - - 2012
Grafting from polymerization was used to synthesize nano-titania/polyurethane (nTiO(2)/polyurethane) composite coatings, where nTiO(2) was chemically attached to the backbone of the polyurethane polymer matrix with a bifunctional monomer, 2,2-bis(hydroxymethyl) propionic acid (DMPA). This bifunctional monomer can coordinate to nTiO(2) through an available -COOH group, with two available hydroxyl groups that ...
Takenaka Mizuki - - 2012
RNA editing is an RNA maturation process that changes the nucleotide present at particular positions (editing sites) in specific RNAs; in plant organelles, the most common nucleotide change is from cytidine (C) to uridine (U). In a mutant suspected of affecting RNA editing, all known editing sites have to be ...
Blease Charlotte Rosalind - - 2012
Major depressive disorder is not only the most widespread mental disorder in the world, it is a disorder on the rise. In cases of particularly severe forms of depression, when all other treatment options have failed, the use of electroconvulsive therapy (ECT) is a recommended treatment option for patients. ECT ...
Lam Matthew - - 2012
BACKGROUND: Chronic rhinosinusitis (CRS) is a heterogeneous disease defined by epithelial inflammation. The link between measures of traditional disease severity and markers of epithelial inflammation is poorly understood as prior research has focused on presence of polyps or degree of eosinophilia. The expression of 3 epithelial derived cytokines implicated in ...
Valencia-Hernández Ignacio - - 2012
The present study investigated the hypothesis that the duration of ovarian hormone deprivation before reintroduction of oestrogen affects the role of oestrogen as a mediator of the contractile function of α(1)-adrenergic receptors. Rats underwent ovariectomy (OVX) or were sham-operated, and the OVX rats were treated with vehicle (corn oil) or ...
Tang Wenjian - - 2012
In chromophore-containing cyclobutane pyrimidine dimer (CPD) model systems, solvent effects on the splitting efficiency may depend on the length of the linker, the molecular conformation, and the oxidation potential of the donor. To further explore the relationship between chromophore structure and splitting efficiency, we prepared a series of substituted indole-T<>T ...
van Hasselt F M - - 2012
Therapeutic drug monitoring to optimize blood plasma concentrations is advised for certain psychiatric drugs. The current standard is to change the dose based on the blood plasma concentration. We present an overview that blood plasma concentrations can also be influenced by adding co-medication based on pharmacokinetic knowledge.We performed a systematic ...
Hedberg Magnus - - 2012
Abstract Objectives: Stroke following cardiac surgery may occur in association to surgery (early) or postoperatively (delayed). The hemispheric distribution of lesions may provide information about embolic routes, which was analyzed here. Design: In 10 809 patients undergoing cardiac surgery, early (n=223) and delayed stroke (n=116) were explored. Symptoms and computed-tomography ...
Hoffman Michele T - - 2012
Huanglongbing (HLB) is one of the most destructive diseases of citrus worldwide. The three known causal agents of HLB are species of α-proteobacteria, 'Candidatus Liberibacter asiaticus' (Las), 'Ca. Liberibacter africanus' and 'Ca. Liberibacter americanus'. Previous studies have found distinct variations in temperature sensitivity and tolerance among these species. Here we ...
Seppala Jonathan E - - 2012
We present a spatially resolved approach for the solvent vapor annealing (SVA) of block copolymer thin films that permits the facile and relatively rapid manipulation of nanoscale ordering and nanostructure orientation. In our method, a localized (point) SVA zone is created through the use of a vapor delivery nozzle. This ...
Xu Xiao - - 2012
A simple and rapid bacterial counting method was developed based on dark-field light-scattering imaging of bacteria and gold nanoparticle (AuNP) reporter simultaneously. Commercially available DH5α E. coli strain was used as the model bacterium to demonstrate the feasibility of the proposed method. With antibody-conjugated AuNPs, the simple sample treatment and ...
Zhang Yi - - 2012
ABSTRACT: BACKGROUND: Cardiac structure and function are well-studied in western countries. However, epidemiological data is still scarce in China. METHODS: Our study was conducted in the framework of cardiovascular health examinations for the current and retired employees of a factory and their family members. According to the American Society of ...
Di Minno Matteo Nicola Dario - - 2012
ABSTRACT: INTRODUCTION: We prospectively evaluated whether hepatic steatosis (HS) and the presence of carotid plaques (CPs) impacts on achieving minimal disease activity (MDA) in psoriatic arthritis (PsA) patients starting tumor necrosis factor (TNF)-alpha blockers treatment. METHODS: Before starting treatment with TNF-alpha blockers, consecutive PsA subjects with an active disease were ...
Zhao Yang - - 2012
Abstract Objective: To investigate the clinical characteristics of mirror syndrome. Methods: Retrospective analysis of cases with mirror syndrome. Data of clinical manifestations, laboratory examinations, placental morphology, treatment and prognosis of these patients were obtained and studied. Results: Five cases satisfying the inclusion criteria for mirror syndrome were identified from our ...
Toran Laura - - 2012
A freeze core sampler was used to characterize hyporheic zone storage during a stream tracer test. The pore water from the frozen core showed tracer lingered in the hyporheic zone after the tracer had returned to background concentration in collocated well samples. These results confirmed evidence of lingering subsurface tracer ...
Tierney Travis S - - 2012
Surgical therapy for the secondary dystonias is generally perceived to be less effective than for primary disease. However, a number of case reports and small open series have recently appeared describing quite favorable outcomes following surgery for some nonprimary dystonias. We discuss surgical treatment options for this group of diverse ...
Eloy Jean Anderson - - 2012
BACKGROUND: Endoscopic endonasal transcribriform (EET) resection of anterior skull base (ASB) tumors results in large defects that may extend the entirety of the cribriform plate. Endoscopic repair of these cribriform defects can often be challenging. We describe our reconstruction technique for large ASB defects after EET resection of ASB tumors. ...
Okawa Makio - - 2012
OBJECTIVE: Prior to 2003, the target blood glucose level at our institute was <200 mg/dl. This target was reassessed in 2004 and again in 2006 based on reports that showed a decreased mortality rate in patients with a target glucose level between 80 mg/dl and 110 mg/dl and subsequent reports ...
Yoshinari Takeshi - - 2012
Babesia ovata is a tick-transmitted hemoprotozoan parasite that infects cattle. In our study, bovine blood samples (n=2,034) were collected from 10 different countries (Brazil, China, Ghana, Japan, Mongolia, the Philippines, South Africa, Sri Lanka, Thailand, and Vietnam) and DNA extracted. The DNA samples were screened using an established and specific ...
Tronic Tristan A - - 2012
Cyclopentadienyl and pentamethylcyclopentadienyl ruthenium(II) complexes have been synthesized with cyclic (RPCH(2)NR'CH(2))(2) ligands, with the goal of using these [Cp(R'')Ru(P(R)(2)N(R')(2))](+) complexes for catalytic O(2) reduction to H(2)O (R = t-butyl, phenyl; R' = benzyl, phenyl; R″ = methyl, H). In each compound, the Ru is coordinated to the two phosphines, positioning ...
Yildiz Saliha Handan - - 2012
Apolipoprotein E (ApoE) gene polymorphisms are thought to be the most important genetic risk factor in the pathogenesis of late onset and sporadic Alzheimer's disease (AD). Moreover, interleukin-1α (IL-1α) is found to be associated with the pathogenesis of AD. In this research, ε2, ε3, and ε4 polymorphisms of ApoE gene ...
Grünwald G K - - 2012
In this study, we determined the in vitro and in vivo efficacy of sodium iodide symporter (NIS) gene transfer and the therapeutic potential of oncolytic virotherapy combined with radioiodine therapy using a conditionally replicating oncolytic adenovirus. For this purpose, we used a replication-selective adenovirus in which the E1a gene is ...
Liu Kai - - 2012
Abstract Induced pluripotent stem cells (iPSCs) can be artificially reprogrammed from somatic cells by overexpression of exogenous transcription factors. The pig has increasingly become an important large animal model for preclinical tests and studies of human diseases; thus, the generation of porcine iPSCs will facilitate research into the efficacy and ...
La Kim Eun - - 2012
A new cyclic tetrapeptide (1), along with known congeners (2 and 3), was isolated from the fungus Phoma sp. derived from the giant jellyfish Nemopilema nomurai. The absolute configuration of 1 was determined using the modified Mosher's method and Marfey's method. Compound 1 displayed a weak suppressive effect on the ...
Hajjaji Nawale - - 2012
Body weight loss during the course of cancer disease has been associated with poor prognosis. Beside cancer-associated cachexia, weight loss can also result from chemotherapy. This work explored whether a model of mammary tumors in female Sprague Dawley rats could be appropriate to study the effect of doxorubicin on body ...
Nomoto Yuji - - 2012
The plant circadian clock generates rhythms with a period close to 24 h, and it controls a wide variety of physiological and developmental events, enabling plants to adapt to ever-changing environmental light conditions. In Arabidopsis thaliana, the clock regulates the diurnal and photoperiodic plant growth including the elongation of hypocotyls ...
Nomoto Yuji - - 2012
In Arabidopsis thaliana, the circadian clock regulates diurnal and photoperiodic plant growth including the elongation of hypocotyls in a time-of-day-specific and short-day (SD)-specific manner. The clock-controlled PHYTOCHROME-INTERACTING FACTOR 4 (PIF4) encoding a basic helix-loop-helix (bHLH) transcription factor plays crucial roles in this regulation. PIF4 is transcribed precociously at the end ...
Codony-Servat Jordi - - 2013
Previous work showed that the NF-κB survival pathway is activated by docetaxel (D) and contributes to D resistance in prostate cancer. In this study we aimed to investigate the dynamics of the relationship between NF-κB and IL-6 in the shift from D-naive castration-resistant prostate cancer (CRPC) to D-resistance in patients ...
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