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Results 501 - 550 of 2845
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Tavares L - - 2012
Here, we report localized, polarized and waveguided electroluminescence (EL) from well aligned organic nanofibres integrated via roll printing on transistor platforms. The localized emission is due to the application of an alternating current voltage to the transistor gate electrodes, which causes sequential injection of holes and electrons into the organic ...
Barker David J P - - 2012
Context: Memorial to Jim Tanner. Objective: To examine the links between early growth and chronic disease in later life. Methods: Literature review. Results: There is now a developmental model for the origins of chronic disease in which the causes to be identified are linked to normal variations in feto-placental, infant ...
Marras Theodore K - - 2012
SUMMARY AT A GLANCE: We evaluated CT features, symptoms and microbiological disease criteria in pulmonary Mycobacterium xenopi. Cavitation and large nodules were associated with microbiologic criteria for disease. Bronchiectasis and small nodules were associated with symptoms. Cavitation and large nodules should be considered as being supportive for early initiation of ...
Solovyov Leonid A - - 2012
Ordered mesostructured mesoporous materials, combining nano-organization with atomic disorder, are both attractive and challenging objects of investigation by X-ray and neutron diffraction. The development of diffraction mesostructure analysis methods and their applications in studies on structural characterization, formation processes and physisorption phenomena in these advanced materials are summarized in this ...
Otto-Hanson Lindsey K - - 2012
Success in biological control of plant diseases remains inconsistent in the field. A collection of well- characterized Streptomyces antagonists (n=19 isolates) was tested for their capacities to inhibit pathogenic Streptomyces scabies (n=15 isolates). There was significant variation among antagonists in ability to inhibit pathogen isolates and among pathogens in their ...
Wängler Björn - - 2012
Proteins previously derivatized with the cross-coupling reagent sulfo-SMCC (4-(N-maleimidomethyl)cyclohexane-1-carboxylic acid 3-sulfo-N-hydroxy-succinimide ester sodium salt) can be easily labeled in high radiochemical yields with the silicon-fluoride acceptor (SiFA) reagent [(18)F]SiFA-SH, obtained via isotopic exchange, by thiol-maleimide coupling chemistry (n = 10). The specific activity of SiFA-SH obtained in a one-step labeling ...
Clapin Helen F - - 2012
Epidemiological evidence suggests that folate may lower the risk of colorectal cancer (CRC) although studies have been inconsistent and some have indicated differences in the effects of naturally occurring dietary folate and the synthetic form of this vitamin, folic acid. Most studies to date have considered CRC as a single ...
Saidun Salilah - - 2012
Visual recording of human subjects is commonly used in biomedical disciplines for clinical, research, legal, academic and even personal purposes. Guidelines on practice standards of biomedical recording have been issued by certain health authorities, associations and journals, but none of the literature discusses this from an Islamic perspective. This article ...
Moorin Rachael - - 2012
OBJECTIVES: Controversy persists over the relationships between health care expenditure, time-to-death and age, undermining attempts to generate convincing predictions for policy. This paper explores the relationships between time-to-death (TTD), age and health care expenditure for Australian Medicare-funded, out-of-hospital services in the last five years of life, assessing if the relationship ...
Kenwright Alan M - - 2012
The preparation of a number of alkyl and alkoxy derivatives of pentacyclo[5.4.0.0(2,6) .0(3,10) .0(5,9) ]undecane-8,11-dione derivatives utilising a cheap, practical, low energy, 'green', single-pass continuous flow photochemical reactor is reported. Their (1)  H and (13) C NMR spectra are fully assigned, revealing some general characteristics not previously reported for this ...
Chen Songbiao - - 2012
Interactions between rice and Magnaporthe oryzae involve the recognition of cellular components and the exchange of complex molecular signals from both partners. How these interactions occur in rice cells is still elusive. We employed robust-long serial analysis of gene expression (RL-SAGE), massively parallel signature sequencing (MPSS), and sequencing by synthesis ...
Horemans Benjamin - - 2012
Urban atmospheres in modern cities carry characteristic mixtures of particulate pollution which are potentially aggravating for chronic respiratory patients (CRP). Although air quality surveys can be detailed, the obtained information is not always useful to evaluate human health effects. This paper presents a novel approach to estimate particle deposition rates ...
Kohda Naohisa - - 2012
Abstract Objective: To measure the forces delivered by thermoplastic appliances made from three materials and investigate effects of mechanical properties, material thickness, and amount of activation on orthodontic forces. Materials and Methods: Three thermoplastic materials, Duran (Scheu Dental), Erkodur (Erkodent Erich Kopp GmbH), and Hardcast (Scheu Dental), with two different ...
Wang Ziwen - - 2012
On the basis of our previous structure-activity relationship (SAR) and antiviral mechanism studies, a series of phenanthroindolizidines and their analogues 3-20 were designed, targeting tobacco mosaic virus (TMV) RNA, synthesized, and systematically evaluated for their antiviral activity against TMV. The bioassay results showed that most of these compounds displayed good ...
Furuyama Taniyuki - - 2012
Supersized: Three pentaazapentaphyrin derivatives, that is, the superazaporphyrins (SAzPs), as well as a superphthalocyanine (SPc) and a mixed low-symmetry derivative have been prepared and characterized. Decaaryl SAzPs have a distorted (4n+2) π structure and show the Q bands at about λ=840-880 nm. These compounds are relatively air stable.
Gyllenhammer Lauren Elizabeth - - 2012
BACKGROUND: Lifetime physical activity (PA) is associated with decreased breast cancer (BC) risk; reports suggest that PA during adolescence contributes strongly to this relationship. PA lowers production of sex hormones, specifically estradiol, or decreases insulin resistance (IR), thereby lowering risk. Overweight Latina adolescents are insulin resistant and exhibit low levels ...
Vicente Js - - 2012
The aim of this work was to study the influence of embryonic and maternal genotype of two lines of rabbits selected by growth rate (line R) and litter size at weaning (line A) on prenatal survival. Embryos were recovered at 48 h of gestation from R and A donors (39 and ...
Chu Fu-Lu - - 2012
Objectives: To determine the effects of heptad repeat regions (HRs) and N-linked carbohydrate sites of the Newcastle disease virus hemagglutinin-neuraminidase (HN) protein on fusion of HN and fusion (F) proteins and HN-F interaction. Methods: We mutated six 'a' residues in the HRs and four asparagines in N-linked carbohydrate sites to ...
Samuel Prinson P - - 2012
The reactions of silylenes with organic azides are quite diverse, depending on the substituents of the silylene center and on the nature of the azide employed. Elusive silaimine with three-coordinate silicon atom L(1)SiN(2,6-Triip(2)-C(6)H(3)) (5) {L(1) = CH[(C═CH(2))(CMe)(2,6-iPr(2)C(6)H(3)N)(2)] and Triip = 2,4,6-triisopropylphenyl} was synthesized by treatment of the silylene L(1)Si (1) ...
Komatsu Yuki - - 2012
Background: Whether procedural termination of persistent atrial fibrillation (AF) is necessary for optimal clinical efficacy still remains controversial. We sought to characterize the patients with persistent AF in whom procedural AF termination impacted an improved clinical outcome after ablation. Methods: We retrospectively assessed 132 patients (61.0 ± 9.3 years, 114 ...
Jeong Seung Hee - - 2012
Recently, microfluidic stretchable electronics has attracted great interest from academia since conductive liquids allow for larger cross-sections when stretched and hence low resistance at longer lengths. However, as a serial process it has suffered from low throughput, and a parallel processing technology is needed for more complex systems and production ...
Gebala Magdalena - - 2012
Label-free electrochemical detection of DNA hybridization with high selectivity and sensitivity is only achievable if the properties of DNA at an electrified interface are understood in depth. After a short summary of concepts of electrochemical DNA detection as well as initial attempts towards label-free DNA assays the review discusses the ...
Zhou Jun - - 2012
In my (DNA) dreams: A tri-G-quadruplex was constructed from three strands (T1-T3) of DNA using duplex formation to guide the G-rich tracts into close proximity with the addition of Li(+) ions. The defined G-quadruplex structure was formed upon addition of Na(+) ions and characterized by gel electrophoresis and spectroscopy.
Lee Jung-Hoon - - 2012
Obtaining a strong and reproducible surface-enhanced Raman scattering (SERS) signal with a narrow distribution of the high SERS enhancement factor (EF) values from the plasmonic nanostructures is critical for better understanding and practical use of the single-molecule SERS (SMSERS) nanoprobes. In this regard, the systematic and thorough studies about the ...
Van Wassenbergh Sam - - 2012
Seahorses and other sygnathid fishes rely on a widening of the snout to create the buccal volume increase needed to suck prey into the mouth. This snout widening is caused by abduction of the suspensoria, the long and flat bones outlining the lateral sides of the mouth cavity. However, it ...
Peck Amy R - - 2012
ABSTRACT: INTRODUCTION: Signal transducer and activator of transcripton-5a (Stat5a) and its close homolog, Stat5b, mediate key physiological effects of prolactin and growth hormone in mammary glands. In breast cancer, loss of nuclear localized and tyrosine phosphorylated Stat5a/b is associated with poor prognosis and increased risk of antiestrogen therapy failure. Here ...
Choi Jong Young - - 2012
An integrated allele-specific polymerase chain reaction (AS PCR) and microarray chip has been developed for multiplex single nucleotide polymorphism (SNP) typing on a portable genetic analyzer instrumentation. We applied the integrated PCR-microarray system for on-site Hanwoo (Korean indigenous beef cattle) identification. Eleven sets of primers were designed, among which ten ...
Saha Pipas - - 2012
Substituted dihydropyrans can be efficiently synthesized in good yields with excellent diastereoselectivity from the reaction of aldehydes or epoxides and ethyl 3-alkyl-3-hydroxy-5-methylhex-5-enoate via an oxonium-ene cyclization reaction catalyzed by trimethylsilyl trifluoromethanesulfonate (TMSOTf) under mild conditions.
Sjoerds Z - - 2012
BACKGROUND: A family history (FH) of alcohol dependence (AD) not only increases the risk for AD, but is also associated with an increased risk for mood and anxiety disorders. However, it is unknown how a FH of AD affects neural substrates in patients with mood and anxiety disorders. In this ...
Cheung Tan To - - 2012
BACKGROUND: Liver resection provides one of the best oncological outcomes for liver metastases in patients with colorectal cancer. However, long-term results concerning laparoscopic resection versus open hepatectomy for stage IV colon cancer are still limited. The aim of this study is to compare the survival outcome of laparoscopic liver resection ...
Farsi Zohreh - - 2012
There is huge number of oligomeric proteins which show allosteric behavior as soon as their allosteric effector is provided. Thermus sp. GH5 methylglyoxal synthase (TMGS) is also a homohexameric protein which displays cooperative behavior when phosphate concentration increases. Previous studies on this enzyme have indicated that binding of phosphate leads ...
Kreuter Justin - - 2012
Thrombotic microangiopathy is a pathological process that results in thrombocytopenia, schistocytes, and organ ischemia. A wide variety of causes of thrombotic microangiopathy have been described, each associated with a different pathological stimulus and predisposition toward certain vascular territories. This review will summarize our understanding of key drugs that have been ...
Kahouadji Y - - 2012
OBJECTIVES: Previous studies in HIV-infected populations have yielded conflicting results on the effect of antiretroviral therapy (ART) on cognition. Our objective was to investigate the effect of several years of ART with stable central nervous system penetration effectiveness (CPE) score on neuropsychological performance in HIV-infected individuals. METHODS: We analysed a ...
Slany Michal - - 2012
The isolation of nontuberculous mycobacteria (NTM) from clinical specimens has become very common in recent years. Such organisms are typically environmental and occasionally pathogenic for humans and animals. Standard diagnosis of mycobacterial infections relies on direct examination and culture. However, molecular tools are now available which allow quicker and more ...
Yeh Li-Hsien - - 2012
A novel polyelectrolyte (PE)-modified nanopore, comprising a solid-state nanopore functionalized by a non-regulated PE brush layer connecting two large reservoirs, is proposed to regulate the electrokinetic translocation of a soft nanoparticle (NP), comprising a rigid core covered by a pH-regulated, zwitterionic, soft layer, through it. The type of NP considered ...
Wang Xiao-Ming - - 2012
ABSTRACT: INTRODUCTION: X-linked adrenoleukodystrophy (X-ALD) is a complex disorder with variable expressivity that affects the nervous, adrenocortical, and male reproductive systems. Although ABCD1 mutations are known to provide the genetic basis for X-ALD, its pathogenesis is not fully elucidated. While elevated very long chain fatty acid (VLCFA) levels in blood ...
Alain Karine - - 2012
Aromatic hydrocarbons are among the main constituents of crude oil and represent a major fraction of biogenic hydrocarbons. Anthropogenic influences as well as biological production leads to exposure and accumulation of these toxic chemicals in the water column and sediment of marine environments. The ability to degrade these compounds in ...
Jamieson Frances F - - 2012
This study examined the antigenic and genetic diversity of serogroup B Neisseria meningitidis (MenB) recovered from invasive meningococcal disease (IMD) cases in Ontario, Canada for the 10 year period of 2001 to 2010 during which no MenB outbreaks had occurred. MenB was found to be responsible for 39% of all ...
Bradford Andrea - - 2012
Introduction.  Placebo responses are substantial in many clinical trials of treatments for female sexual dysfunctions (FSDs). Recent studies from other fields suggest a need to reconceptualize placebo response and to design future trials accordingly. Aim.  The aims of this review are to (i) summarize current conceptualizations of placebo response in ...
Paier S - - 2012
For the first time we present the case of a microsurgical reconstruction with an osteo-tendo-cutaneous free flap harvested from the medial femoral condyle for the coverage of a bone-tendon-soft tissue defect of the foot.�
Li Philip Hei - - 2012
Objective. This study aims to identify the existence of, and relationship between autoantibody clusters and clinical subsets in Chinese SLE patients.Methods. Data from 1928 SLE patients from Hong Kong were analysed. Using cluster analysis, patients were grouped by autoantibodies into clusters. The frequencies of various clinical manifestations were then compared ...
Wang Xi - - 2012
Abstract miR-34a was identified as one of the downregulated microRNAs (miRNAs) in human lung cancer. However, the precise biological role of miR-34a in p53 deficient lung cancer cell lines remains largely elusive. In the present study, we aimed to identify the role of miR-34a in the regulation of lung cancer ...
Martí-Gastaldo Carlos - - 2012
Pepped up: Notwithstanding the intrinsic conformational flexibility of peptides, [Zn(Gly-Thr)(2) ] behaves as a robust porous metal-organic framework thanks to the rigidity introduced by the use of Gly-Thr. This rigidity arise from the sequence of amino acids in the dipeptide that locks its conformational flexibility in the framework.
Stranne Johan - - 2012
Abstract Objective.The aim was to explore how erectile dysfunction (ED) correlates with increasing age and a number of demographic, physical and lifestyle factors. Material and methods. A questionnaire was sent to a random sample (10 458) of men living in Gothenburg, Sweden, in 1992. The men were from the age ...
Sgro Michael J - - 2012
Frustrating ruthenium: The ruthenium complex 1 is shown to bind carbon dioxide or aldehyde in a manner similar to a frustrated Lewis pair. Compound 2 catalyzes the reduction of CO(2) in the presence of pinacolborane (HBpin), yielding MeOBpin and O(Bpin)(2) (see picture; Ru red, P orange, N green, O light ...
Kurra Narendra - - 2012
We describe a transfer-free method for the fabrication of nanocrystalline graphene (nc-graphene) on SiO(2) substrates directly from patterned carbonaceous deposits. The deposits were produced from the residual hydrocarbons present in the vacuum chamber without any external source by using an electron beam induced carbonaceous deposition (EBICD) process. Thermal treatment under ...
Mendiratta P - - 2012
Objectives: To investigate national trends in percutaneous endoscopic gastrostomy (PEG) tube placement for hospitalized elderly patients from 1993to 2003. Methods: Retrospective analysis of patients ≥65 years of age with PEG tube placement from 1993 to 2003 from the Nationwide Inpatient Sample (NIS) database was utilized to calculate PEG placement rates ...
Capra Louise - - 2012
OBJECTIVES: To determine and identify the characteristics and circumstances of femur fractures in ambulatory young children. DESIGN AND SETTING: Retrospective review of 203 ambulatory children, between 1 and 5 years old, presenting with femur fractures to an urban paediatric hospital over a 10-year period. χ(2) And Student's t test were ...
Hawley Karen A - - 2012
BACKGROUND: Sinonasal respiratory epithelial adenomatoid hamartoma (REAH) is a benign glandular proliferation with ciliated epithelium. Little is known about REAH, with only a few published case reports appearing since its original description in 1995. Classically described as an isolated polypoid lesion arising from the nasal septum, more recent descriptions also ...
Pawlicki Miłosz - - 2012
Behind the wheel: A 10 nm diameter nanoring, containing 24 porphyrin units, has been created by a Vernier-templating self-organization of hexa- or octadente templating units and linear covalently linked porphyrin oligomers. Coordination of a bidentate ligand triggers a conversion of the molecular nanocylinder into a molecular nanoannulus to afford the ...
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