Search Results
Results 301 - 350 of 1352
< 2 3 4 5 6 7 8 9 10 11 12 >
Zhang Haitao - - 2012
A rational synthetic method is developed to produce monodisperse metal sulfide nanocrystals (NCs) in organic non-polar solutions by using (NH(4))(2)S as a sulfide precursor. (NH(4))(2)S is stabilized in an organic primary amine solution and exhibits high reactivity toward metal complexes. This novel technique exhibits wide applicability for the organic phase ...
Li Yu-Feng - - 2012
Due to a long history of extensive mercury mining and smelting activities, local residents in Wanshan, China, are suffering from elevated mercury exposure. The objective of the present study was to study the effects of oral supplementation with selenium-enriched yeast in these long-term mercury-exposed populations. One hundred and three volunteers ...
Hardefeldt Prue J - - 2012
The hyperinsulinaemia associated with type 2 diabetes and the known proliferative effects of insulin has lead to the hypothesis that diabetes mellitus increases the risk of breast cancer. The aim of this meta-analysis was to collate and analyse all primary observational studies investigating the risk of breast cancer associated with ...
Hirshfeld-Becker Dina R - - 2012
OBJECTIVE The authors examined the specificity and course of psychiatric disorders from early childhood through adolescence in offspring of parents with confirmed panic disorder and major depressive disorder. METHOD The authors examined rates of psychiatric disorders at 10-year-follow-up (mean age, 14 years) in four groups: offspring of referred parents with ...
Finkenzeller Thomas - - 2012
PURPOSE: To evaluate if the use of BLADE sequences might overcome some limitations of magnetic resonance imaging (MRI) in the extracranial head and neck, which is a diagnostically challenging area with a variety of artifacts and a broad spectrum of potential lesions. MATERIALS AND METHODS: After informed consent and Institutional ...
Neely J Gail - - 2012
Multivariable analyses are complex statistical methods to evaluate the impact of multiple variables on outcomes of interest. Books have been written on each of these methods detailing the mathematical and statistical objectives and processes. However, we have found very little in the way of brief reports that help the nonstatistically ...
Jun Bo Ram - - 2012
BackgroundThe radiation dose of coronary computed tomography (CT) angiography (CCTA) is generally higher than that of CT scans of other parts of the body, and there is concern that the high radiation dose may result in increased cancer risk. Although various techniques have recently been introduced to lower the radiation ...
Moayedi Massieh - - 2012
Several theoretical frameworks have been proposed to explain the physiological basis of pain, although none yet completely account for all aspects of pain perception. Here, we provide a historical overview of the major contributions, ideas, and competing theories of pain from ancient civilizations to Melzack and Wall's Gate Control theory ...
Dai Boyi - - 2012
BACKGROUND:Anterior cruciate ligament (ACL) reinjury rates are high in adolescent patients. Knee braces are commonly used after ACL reconstruction to prevent reinjury during return to sports. HYPOTHESIS:Adolescent patients following ACL injury would demonstrate a decreased vertical ground-reaction force, knee extension moment, knee flexion angle, and knee flexion velocity on the ...
Fortunato Rodrigo Soares - - 2012
Background: Dual oxidases (DUOX1 and DUOX2) are NADPH oxidases involved in hydrogen peroxide production necessary for thyroid hormonogenesis, but recently the NADPH oxidase 4 (NOX4) has also been described in the thyroid gland. The prevalence of thyroid disease is higher in women, and the basis for this difference might involve ...
Le Bastard Nathalie - - 2012
The current treatment for Alzheimer's disease (AD) is purely symptomatic, but medications interfering with underlying pathophysiological processes are being developed. To evaluate a possible disease-modifying effect, cerebrospinal fluid (CSF) biomarkers with a direct link to the underlying pathophysiology, such as amyloid-β1-42 (Aβ1-42), total tau protein (T-tau), and hyperphosphorylated tau (P-tau181P), ...
Darvish-Kazem Saeed - - 2012
Patients receiving anticoagulant or antiplatelet therapy who require noncardiac surgery represent a common yet challenging clinical problem. Clinicians must balance the risk of thromboembolic and major adverse cardiovascular events that are associated with interrupting these therapies, against the risk of bleeding from continuing these drugs in the perioperative period. Identifying ...
Ng Lih Chyuan - - 2012
Previous studies in pulmonary artery smooth muscle cells (PASMCs) showed that acute hypoxia activates capacitative Ca(2+) entry (CCE) but the molecular candidate(s) mediating CCE caused by acute hypoxia remain unclear. The present study aimed to determine if TRPC1 and Orai1 interact with STIM1 and mediate CCE caused by acute hypoxia ...
Cowie B - - 2012
BACKGROUND: /st>Developments in transducer technology have enabled the use of three-dimensional transoesophageal echocardiography (3D TOE) in the operating theatre. Transthoracic echocardiography (TTE) 3D left ventricular (LV) volumes and ejection fraction (EF) agree better with magnetic resonance imaging (MRI) measurements, with less intra- and inter-observer variability compared with 2D. This has ...
Merindol Natacha - - 2012
CMV and varicella zoster virus (VZV) are significant causes of morbidity and mortality following umbilical cord blood transplantation (UCBT). However, the kinetics of reconstitution and protective potential of antiviral cell-mediated immune responses following UCBT remain poorly characterized. In this study, the reconstitution of CMV- and VZV-specific T cell responses was ...
Correale Jorge - - 2012
OBJECTIVE: Our objective was to evaluate risk of exacerbations in multiple sclerosis (MS) patients undergoing assisted reproduction technology (ART) infertility treatment. METHODS: Sixteen patients with relapsing-remitting MS subjected to 26 ART treatment cycles receiving gonadotropin-releasing hormone (GnRH) agonists and recombinant follicle-stimulating hormone were studied prospectively. The baseline study period encompassed ...
Bautista-Garcia Pablo - - 2012
Zona occludens-2 (ZO-2) is a protein present at the tight junction and nucleus of epithelial cells. ZO-2 represses the transcription of genes regulated by the Wnt/β-catenin pathway. This pathway plays a critical role in podocyte injury and proteinuria. Here we analyze if the over-expression of ZO-2 in the glomerulus, by ...
Gal Joseph - - 2012
In 1886, Italian chemist Arnaldo Piutti isolated, for the first time, d-asparagine, the enantiomer of the known l-asparagine. He obtained 100 g of d-asparagine from 6500 kg of vetches. Using an ingenious synthetic scheme, Piutti established the chemical structure of asparagine and demonstrated that his isolation of d-asparagine from plants was not ...
Di Martino Maria T - - 2012
PURPOSE: Deregulated expression of microRNAs (miRNAs) has been demonstrated in multiple myeloma (MM). A promising strategy to achieve a therapeutic effect by targeting the miRNA regulatory network is to enforce the expression of miRNAs that act as tumor suppressor genes, such as miR-34a EXPERIMENTAL DESIGN: Here, we investigated the therapeutic ...
Hu Chiung-Wen - - 2012
Areca nut is a carcinogen to human and has been strongly associated with oral pre-malignant and malignant diseases. Previous studies speculated the presence of unknown direct-acting mutagens present in aqueous extracts of areca nut. We hypothesized whether any direct-acting alkylating agents present in areca nut and its commercial products. In ...
Kole Goutam Kumar - - 2012
This tutorial review discusses recent literature on coordination polymers and metal-organic frameworks (MOFs) that exhibit solid-state reactivity and structural transformation under various experimental conditions. Removal or exchange of solvents and guest molecules, exposure to reactive vapours, and external stimuli such as heat, light or mechanochemical force cause such structural transformations ...
Kim Andrea A - - 2012
Background: Honduras has one of the highest HIV prevalence rates in Central America. Data on HIV incidence is needed to identify groups at greatest need of prevention interventions to inform the HIV response. Methods: We applied a test for recent infection to HIV-positive specimens from a biologic and behavioral survey ...
Chiu Tsan-Yu - - 2012
NTPDases (Apyrases) (EC 3.6.1.5) hydrolyze di- and triphosphate nucleotides, but not monophosphate nucleotides. They are categorized as E-type ATPases, have a broad divalent cation (Mg(2+), Ca(2+)) requirement for activation, and are insensitive to inhibitors of F-type, P-type, and V-type ATPases. Among the seven NTPDases identified in Arabidopsis, only APYRASE 1 ...
Mefford Heather C - - 2012
Advances in technology are rapidly changing the field of medical genetics in both the research laboratory and the clinic. With the use of next-generation, or massively parallel, DNA sequencing, it is possible to determine the sequence of essentially all genes in an individual's genome - referred to as the exome ...
Gwon Dong Il - - 2012
BackgroundAs bacterial attachment and subsequent biofilm formation on the surface of a stent lumen may be important in initiating sludge formation and subsequent stent blockage, there is a need for antibiotic-eluting stents to prevent sludge formation by bacterial attachment and colonization.PurposeTo evaluate the antimicrobial effects of cefotaxime-eluting covered self-expandable stents ...
Tamaki Hiroya - - 2012
Mismatched human leukocyte antigens (HLAs) on leukemic cells can be targeted by donor T cells in HLA-mismatched/haploidentical stem cell transplantation. In two cases of acute myeloid leukemia with t(6;11)(q27;q23) abnormality presented here, flow cytometry analysis showed a lack of HLA-A unshared between recipients and donors in relapsing leukemic cells after ...
Moniz Sónia - - 2012
The gene encoding protein kinase WNK2 was recently identified to be silenced by promoter hypermethylation in gliomas and meningiomas, suggesting a tumour suppressor role in these brain tumours. Following experimental depletion in cell lines, WNK2 was further found to control GTP-loading of Rac1, a signalling GTPase involved in cell migration ...
Huang Aisheng - - 2012
Making use of the preferred adsorption affinity and capacity to CO(2) as well as the highly porous structure with huge cavities of 2.4 nm, a highly permeable and selective ZIF-95 molecular sieve membrane was developed for the separation of H(2) from CO(2).
Côté José - - 2012
We conducted a study of the acceptability and feasibility of a web application which was designed to empower people living with HIV to manage their daily antiretroviral therapies. The application (VIH-TAVIE) consists of four interactive computer sessions with a virtual nurse who guides the user through a learning process aimed ...
Raote Ishier - - 2012
G protein-coupled receptor (GPCR) signalling is modulated by endocytosis and endosomal sorting of receptors between degradation and recycling. Differential regulation of these processes by endogenous ligands and synthetic drugs is a poorly understood area of GPCR signalling. Here, we describe remarkable diversity in the regulation of trafficking of a GPCR ...
Harner Holly M - - 2012
Many women enter prison with significant mental health conditions. Without appropriate intervention during incarceration, there is the potential for these conditions to worsen during confinement. As a result, women, most of whom will eventually be released from prison, might return to their families and communities with even more complex mental ...
Stack J Conrad - - 2012
Models of infectious disease spread that incorporate contact heterogeneity through contact networks are an important tool for epidemiologists studying disease dynamics and assessing intervention strategies. One of the challenges of contact network epidemiology has been the difficulty of collecting individual and population-level data needed to develop an accurate representation of ...
Jette Nathalie - - 2012
Continuous EEG monitoring (cEEG) is increasingly employed to detect nonconvulsive seizures (NCSz) and nonconvulsive status epilepticus (NCSE) in critically ill patients. A recent international survey of 338 neurologists found that 83% use cEEG at least monthly.(1) The growth in cEEG utilization has led to an increase in the recognition of ...
Kang Sun Hee - - 2012
A ganglioneuroma is an extremely rare benign neoplasm composed of neural elements, including mature ganglion cells that originate from the sympathetic ganglia. It is located most frequently in the posterior mediastinum and can be found in the retroperitoneum, including the adrenal medulla.It may evolve from a differentiating neuroblastoma or may ...
Raymond Andrew R - - 2012
AIMS: A reduced average leucocyte telomere length is associated with ischaemic heart failure. Whether this relationship represents a cause or consequence of heart failure or is attributed to associated risk factors and coronary artery disease is uncertain. We evaluated if average leucocyte telomere length is associated with idiopathic dilated cardiomyopathy ...
Mansouri-Attia Nadéra - - 2012
In mammals, successful pregnancy is dependant in part on the adaptation or regulation of the maternal immune system to prevent the rejection of the embryonic semi-allograft. A modification in Th cell function and secretion is a requirement for the establishment and maintenance of pregnancy. Although there is strong evidence from ...
Tran Bich - - 2012
Evidence is accumulating to suggest that higher exposure to solar ultraviolet radiation (UVR) is associated with decreased risk of internal cancers, but data for ovarian cancer are unclear. We aimed to examine the association between lifetime ambient UVR and ovarian cancer in a population-based case control study. The study included ...
Scheidler Capi Seeger - - 2012
The most typical symptom of Chiari malformation type I in children is headache. The authors describe a 14-year-old girl who presented with a 3-year history of gait decline and no headache, which is very unusual. After surgery to correct the Chiari I malformation, the patient's gait improved; however, she went ...
Blanco Rodriguez Josefa - - 2012
Accurate homolog synapsis during meiosis is essential for faithful chromosome segregation and formation of viable gametes. The finding of Spo11-dependent γH2AX formation during leptotene and data on mutant mice have led to the notion that synapsis in mammals depends on meiotic DNA double-stranded break (DSB) repair. A second wave of ...
Meyer Elaine C - - 2012
OBJECTIVE:: To explore how practitioners in the United States respond to the question "What would you do if this were your child?" during realistic enactments with professional actors. DESIGN:: Descriptive study of realistic pediatric critical care enactments. SETTING:: Pediatric critical care. SUBJECTS:: Interprofessional practitioners who enrolled in the Program to ...
Spermon Deborah - - 2012
In this article, we report on a phenomenological study of experiences of recovery of 7 women with histories of childhood maltreatment. We propose a model that recalls the Anglo-Franc etymological origins of rekeverer: to regain consciousness, health, or strength. Dimensions include development of a selfhood; tasks of connection and separation; ...
Moriwaki Kumi - - 2012
BACKGROUND: Intercultural differences influence acute inpatient psychiatric care systems. AIMS: To evaluate characteristics of acute inpatient care in a German and a Japanese hospital. METHOD: Based on a sample of 465 admissions to the Psychiatric State Hospital Regensburg (BKR) and 91 admissions to the Hirakawa Hospital (HH) over a six-month ...
Shao Liming - - 2012
Ventilation is very important during the biodrying process because it affects the biodrying efficiency and secondary pollution. In this study, three ventilation modes-intermittent negative ventilation (IN), continuous negative ventilation (CN) and intermittent positive ventilation (IP)-were used to provide the same amount of total air during biodrying of municipal solid waste ...
Lamarca Nicole Holuba - - 2012
Spinal muscular atrophy is an autosomal recessive neurodegenerative disease caused by homozygous mutation to the survival motor neuron 1 (SMN1) gene. Historically, spinal muscular atrophy has been considered to almost exclusively affect the function and survival of alpha motor neurons of the spinal cord and brainstem. With the development of ...
Zamboni Paolo - - 2012
ABSTRACT: BACKGROUND: Multiple sclerosis (MS) is a chronic inflammatory demyelinating disease of the central nervous system with a disabling progressive course. Chronic cerebrospinal venous insufficiency (CCSVI) has recently been described as a vascular condition characterized by restricted venous outflow from the brain, mainly due to blockages of the internal jugular ...
Aser Raed - - 2012
Objective To determine the pacing and sensing properties of different temporary epicardial pacemaker electrodes after cardiac surgery depending on position at the heart and time after surgery.Methods From September 2009 to October 2010, 60 patients undergoing cardiac surgery were prospectively randomized into two groups: group O: Osypka-electrodes (n = 30), group M: Medtronic-electrodes (n = 30). ...
Costanza-Robinson Molly S - - 2012
Surfactant miscible-displacement experiments represent a conventional means of estimating air-water interfacial area (A(I)) in unsaturated porous media. However, changes in surface tension during the experiment can potentially induce unsaturated flow, thereby altering interfacial areas and violating several fundamental method assumptions, including that of steady-state flow. In this work, the magnitude ...
Shigeta Toshimasa - - 2012
BACKGROUND: The inhibition of dipeptidylpeptidase-4 (DPP4) protects the heart from acute myocardial ischemia. However, the role of DPP4 in chronic heart failure independent of coronary artery disease remains unclear. METHODS AND RESULTS: We first localized the membrane-bound form of DPP4 (m-DPP4) to the capillary endothelia of rat and human heart ...
Kersh Gilbert J - - 2012
BACKGROUND: Coxiella burnetii, an obligate intracellular organism, is the causative agent of the zoonotic disease Q fever. The seroprevalence rate for Q fever in the United States is 3.1%, suggesting a high number of infections each year. However, fewer than 200 cases of Q fever are reported to the CDC ...
Decock Anneleen - - 2012
ABSTRACT: BACKGROUND: Accurate outcome prediction in neuroblastoma, which is necessary to enable the optimal choice of risk-related therapy, remains a challenge. To improve neuroblastoma patient stratification, this study aimed to identify prognostic tumor DNA methylation biomarkers. RESULTS: To identify genes silenced by promoter methylation, we first applied two independent genome-wide ...
< 2 3 4 5 6 7 8 9 10 11 12 >