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Wootton David M - - 2012
Systemic delivery of tissue-type plasminogen activator (t-PA) to dissolve a thrombus after a heart attack or stroke is accompanied by the risk of hemorrhage. A recent study shows the use of nanoaggregates to target t-PA to the thrombus in mouse models of mesenteric injury and pulmonary embolism.
Byeon Jeong Hoon - - 2012
Herein we report the development of anisotropic bimetallic nanoparticles where aerosol gold nanoparticles served as the seeds for the continuous deposition of silver atoms on their surfaces. Initially, aerosol gold nanoparticles were formed by spark discharge and then injected into a silver precursor solution in an impinging device. The gold ...
Toldi Gergely - - 2012
Objective: Soluble urokinase plasminogen activator receptor (suPAR) is a biomarker of systemic inflammation. We aimed to characterize plasma suPAR levels in SLE patients. Methods: We measured plasma suPAR, C reactive protein (CRP) and erythrocyte sedimentation rate (ESR) in 89 SLE patients and 29 healthy controls. Results: suPAR and ESR values ...
Kavalakis Ioannis - - 2012
OBJECTIVE: To evaluate the routine midsagittal view of the posterior brain at the 11-13 weeks' ultrasound examination, for predicting open neural tube defects. METHODS: Posterior brain was examined midsagittally for normality of the four-line view (upper and lower border of the brain stem, the choroid plexus of the fourth ventricle and ...
Wang Linlin - - 2012
Various CuO nanostructures have been well studied as anode materials for lithium ion batteries (LIBs); however, there are few reports on the synthesis of porous CuO nanostructures used for anode materials, especially one-dimensional (1D) porous CuO. In this work, novel 1D highly porous CuO nanorods with tunable porous size were ...
Hesse Deike - - 2012
Lipid droplets carrying triglycerides and cholesteryl esters are emerging as dynamic cellular organelles that are generated in nearly every cell. They play a key role in lipid and membrane homeostasis. Abnormal lipid droplet dynamics are associated with the pathophysiology of many metabolic diseases, such as obesity, diabetes, atherosclerosis, fatty liver, ...
Craig Eva - - 2012
OBJECTIVE: A variety of methods are available for defining undernutrition (thinness/underweight/under-fat) and overnutrition (overweight/obesity/over-fat). The extent to which these definitions agree is unclear. The present cross-sectional study aimed to assess agreement between widely used methods of assessing nutritional status in children and adolescents, and to examine the benefit of body ...
Zhou Weijia - - 2012
MoS(2) nanosheet-coated TiO(2) nanobelt heterostructures-referred to as TiO(2) @MoS(2) -with a 3D hierarchical configuration are prepared via a hydrothermal reaction. The TiO(2) nanobelts used as a synthetic template inhibit the growth of MoS(2) crystals along the c-axis, resulting in a few-layer MoS(2) nanosheet coating on the TiO(2) nanobelts. The as-prepared ...
- - 2012
To the Editor: Boyer (July 12 issue)(1) reports that use of naloxone to treat opioid overdose is logical because it is a direct antagonist of mu opioid receptors. Other strategies for treating opioid-induced respiratory depression and oversedation are now plausible and should be developed as alternatives to single-drug therapy with ...
Carro Antonia M - - 2012
Chemicals are widely used in aquaculture and one of the main recipients of these analytes is the aquatic environment. The aim of this work was to develop and validate a simple and sensitive method for the determination of multiclass chemotherapeutic agents in farmed fish and shellfish using matrix solid-phase dispersion ...
Lippi G - - 2012
INTRODUCTION: Nucleated red blood cells (NRBCs) and reticulocytes are early and important measures of red blood cells' (RBCs) turnover, but little is known on how spurious hemolysis may affect the reliability of these parameters. MATERIALS AND METHODS: Ten EDTA-anticoagulated samples were divided into three aliquots. The first was immediately tested, ...
Shinoda Satoshi - - 2012
Structural dynamism plays important roles in artificial and biological systems, because it controls structures and functions of various molecules and assemblies. In this review, molecular recognition and self-assembling behavior of dynamic armed cyclen-metal complexes are discussed at the molecular and supramolecular levels. These metal complexes provide useful platforms for molecular ...
Kooijmans H - - 2012
Purpose: To evaluate the effectiveness of a 16-week self-management intervention on physical activity level and self-management skills (self-efficacy, proactive coping and problem solving skills) in persons with chronic SCI. Method and design: Multicenter randomized controlled trial (RCT). Eighty persons with a SCI for at least 10 years and aged 18 ...
Hutchinson Marie - - 2012
HUTCHINSON M and JACKSON D. Nursing Inquiry 2012 [Epub ahead of print] Transformational leadership in nursing: towards a more critical interpretation Effective nurse leadership is positioned as an essential factor in achieving optimal patient outcomes and workplace enhancement. Over the last two decades, writing and research on nursing leadership has ...
Naseem M Talha - - 2012
Because of the limitations of the X-ray hardware systems in mammogram machines, the quality of the breast mammogram images may undergo from poor resolution or low contrast. Quantum noise occurs in the mammogram images during acquisition due to low-count X-ray photons. In this work, an adaptive frost filter has been ...
Goldberg Debora Goetz - - 2012
OBJECTIVE: To understand what motivates primary care practices to engage in practice improvement, identify external and internal facilitators and barriers, and refine a conceptual framework. DATA SOURCES: In-depth interviews and structured telephone surveys with clinicians and practice staff (n = 51), observations, and document reviews. STUDY DESIGN: Comparative case study of primary ...
Chen Yijie - - 2012
SCOPE: Mushrooms are well known for their nutritional and medicinal value. Agrocybe aegerita has been used as a nutritious food around the world and for its herbal medicinal properties in Asia. In recent years, several antitumor proteins have been identified from A. aegerita. The objective of this study was to ...
McLucas Bruce - - 2012
Abstract Objective:This paper seeks to evaluate the ability to conceive and deliver term pregnancies following uterine artery embolization. Methods: We conducted a retrospective chart review of patients under the age of 40 who indicated a desire for fertility prior to embolization. Patients were questioned regarding attempts to conceive, subsequent pregnancies, ...
Wan Shunzhou - - 2012
Janus kinase 2 (JAK2) is a protein tyrosine kinase implicated in signalling by specific members of the cytokine receptor family. Although it has been established that the JAK2 tyrosine kinase is negatively regulated by the JAK homology 2 (JH2) pseudokinase domain, the underlying mechanism of JH2 mediated regulation remains elusive. ...
Si Cheng - - 2012
The driving mechanism of the metal-insulator transition (MIT) in VO(2) has always attracted attention, in particular with regards to understanding if and how the doping mechanism may tune the MIT transition temperature. However, due to the lack of detailed local structural information, in this oxide the underlying MIT mechanism is ...
Larrea Edurne S - - 2012
The three-dimensional Co(pym)(VO(3))(2), , hybrid compound, where pym is pyrimidine, has been synthesized under mild hydrothermal conditions at 120 °C. The compound has been characterized by FT-IR spectroscopy, elemental analysis, thermogravimetric measurements, thermodiffractometry, UV-Vis spectroscopy, temperature-dependent magnetic susceptibility and magnetization, and finally a study of specific heat has been performed. ...
Chang Chin Hao - - 2012
Lung cancer is the leading cause of cancer death worldwide as well as in Taiwan. Interleukin-6 (IL-6) is a multifunctional cytokine and has been implicated in tumor progression. The present study recruited 245 patients with advanced (Stage 3B/4) non-small cell lung cancer (NSCLC) that had received chemotherapy, to evaluate associations ...
Levallois Clement - - 2012
The social and neural sciences share a common interest in understanding the mechanisms that underlie human behaviour. However, interactions between neuroscience and social science disciplines remain strikingly narrow and tenuous. We illustrate the scope and challenges for such interactions using the paradigmatic example of neuroeconomics. Using quantitative analyses of both ...
Schmitt Markus - - 2012
Of the 120 known human papillomaviruses (HPV), 51 HPV types infect the genital mucosa. Very little is known about the prevalence and viral load of the majority of these low-risk (Lr-) HPV types in screening populations. We determined the prevalence of 51 HPV types and 3 subtypes in 999 consecutive ...
Throckmorton Douglas C - - 2012
To the Editor: Boyer (July 12 issue)(1) reports that use of naloxone to treat opioid overdose is logical because it is a direct antagonist of mu opioid receptors. Other strategies for treating opioid-induced respiratory depression and oversedation are now plausible and should be developed as alternatives to single-drug therapy with ...
Chen Yang - - 2012
The present study attempted to test the postulate that sounds of a foreign language that are familiar can be produced with less accuracy than sounds that are new to second language (L2) learners. The first two formant frequencies (F1 and F2) were obtained from the 11 English monophthong vowels produced ...
Yanagisawa Michiro - - 2012
Abstract Background and purpose. Giant cell tumor of bone (GCT) is sometimes difficult to distinguish from other giant-cell-rich tumors such as chondroblastoma (CHB) and aneurysmal bone cyst (ABC). The usefulness of p63 as a diagnostic marker for GCT is controversial. While there have been no reports about p63 as a ...
Ileri Nazar - - 2012
Molecular transport properties in short cylindrical and pyramidal nanopores are investigated by mesoscale dissipative particle dynamics simulations. We examine the effect of pore geometry, size, flow direction, particle diameter and electrostatic forces on membrane flux, selectivity and fouling. Biomolecules of various sizes are represented by spherical particles as they move ...
Mathew Thomas - - 2012
Mesoporous ferrihydrite nanoparticles with incorporated Mn (MMnFh) were prepared for the first time, and MMnFh exhibits excellent performance in removing organic contaminants (CH(3)CHO and toluene) in air. The interesting physico-chemical properties and remarkable activity of MMnFh give great commercial potential in air purification application in diverse sectors.
Goghari V M - - 2012
BACKGROUND: Hallucinations are a major aspect of psychosis and a diagnostic feature of both psychotic and mood disorders. However, the field lacks information regarding the long-term course of hallucinations in these disorders. Our goals were to determine the percentage of patients with hallucinations and the relationship between hallucinations and recovery, ...
Liu Ruchuan - - 2012
Cadherins, a large family of calcium-dependent adhesion molecules, are critical for intercellular adhesion. While crystallographic structures for several cadherins show clear structural similarities, their relevant adhesive strengths vary and their mechanisms of adhesion between types I and II cadherin subfamilies are still unclear. Here, stretching of cadherins was explored experimentally ...
Held Leonhard - - 2012
Infectious disease data from surveillance systems are typically available as multivariate times series of disease counts in specific administrative geographical regions. Such databases are useful resources to infer temporal and spatiotemporal transmission parameters to better understand and predict disease spread. However, seasonal variation in disease notification is a common feature ...
Steinemann Daniel C - - 2012
Abstract Introduction: We report our experience and learning curve in single-port laparoscopic cholecystectomy (SPLC) using an internal anchored retraction system. Methods: Usefulness of the retraction system was analysed in 18 SPLC. The first eight, the following ten SPLC and 20 consecutive four-port laparoscopic cholecystectomies (4PLC) were compared. Duration of operation, ...
Ott Susan M - - 2012
To the Editor: In a recent pooled analysis of vitamin D dose requirements for fracture prevention, Bischoff-Ferrari and colleagues (July 5 issue)(1) reanalyzed data from clinical trials by taking into account vitamin D supplementation taken by participants in addition to the study medication. This reanalysis provides a more accurate estimation ...
Ghosh Mimi M Department of Epidemiology and Biostatistics, The George Washington University, Washington, DC 20037, USA. - - 2013
Studies on HIV acquisition and transmission in women exposed to sexual trauma throughout their life cycle are lacking, but some findings suggest that rates of HIV acquisition through coercive sex are significantly higher than that seen in consensual sex. Sexual trauma can also occur as a result of female genital ...
Rapaport Sivan - - 2012
BACKGROUND: Shared decision making (SDM) encourages the patient to play a more active role in the process of medical consultation and its primary objective is to find the best treatment for a specific patient. Recent findings, however, show that patient preferences cannot be easily or accurately judged on the basis ...
Bologna Matteo - - 2012
Paired-pulse transcranial magnetic stimulation (TMS) is used to measure the excitability of interhemispheric inhibition (IHI) between the hand areas of the two motor cortices. It varies from person to person, and is highly predictive of individual differences in callosal anatomy (fractional anisotropy) and even motor behaviour, e.g. the amount of ...
Protudjer Jennifer - - 2012
Objective. Low physical activity and high sedentary behavior are associated with adverse health outcomes, including asthma. The purposes were to ( 1 ) determine if low physical activity and/or high screen time increase the risk of asthma and airway hyperresponsiveness (AHR) in youth and ( 2 ) determine if weight ...
Hartfelder Urs - - 2012
Efficient catalysts are of extraordinary importance for the development of efficient chemical processes as well as applications such as energy storage. Rational development of catalysts requires a mechanistic understanding of the catalytic reaction. Since steady-state investigations are insufficient to gain mechanistic understanding, transient methods such as SSITKA and frequency response ...
Beer Beate - - 2012
Among numerous available genotyping techniques, mass spectrometry (MS) based methods play a major role in providing high quality genotype data at reasonable costs for research and diagnostics, e.g. for pharmacogenetic applications. Ion-pair reversed-phase liquid chromatography hyphenated to electrospray ionization time-of-flight MS (ICEMS) is, for example, a powerful instrument that allows ...
Ruiz-Narváez Edward A EA Slone Epidemiology Center at Boston University, Boston, MA 02215, USA. - - 2013
Genome-wide association studies have identified a multitude of single-nucleotide polymorphisms (SNPs) associated with a wide spectrum of human phenotypic traits. However, the SNPs identified so far do not explain much of the expected genetic variation and they are poor predictors of the occurrence of disease. I recently advanced the hypothesis ...
De Freitas Jilian N JN Chemistry Institute, University of Campinas, Campinas, P.O Box 6154, 13083970, - - 2012
CdSe(ZnS) core(shell) aerogels were prepared from the assembly of quantum dots into mesoporous colloidal networks. The sol-gel method produces inorganic particle interfaces with low resistance to electrical transport while maintaining quantum-confinement. The photoelectrochemical properties of aerogels and their composites with poly(3-hexylthiophene) are reported for the first time.
Yüksel Yusuf - - 2012
We have presented dynamic phase transition features and stationary-state behavior of a ferrimagnetic small nanoparticle system with a core-shell structure. By means of detailed Monte Carlo simulations, a complete picture of the phase diagrams and magnetization profiles has been presented and the conditions for the occurrence of a compensation point ...
Chou Stella T - - 2012
Red blood cell (RBC) transfusions can be life-sustaining in chronic inherited anaemias, such as thalassaemia, and the indications for blood transfusions in patients with sickle cell disease continue to expand. Complications of transfusions, such as allosensitization, can create significant medical challenges in the management of patients with haemoglobinopathies. This review ...
- - 2012
To the Editor: Kang et al. (June 28 issue)(1) report significantly better outcomes with early surgery than with conventional treatment in patients with infective endocarditis and vegetations with a diameter greater than 10 mm. More than 90% of the patients in their study had severe aortic-valve or mitral-valve regurgitation; however, ...
Liu Xin - - 2012
We investigated the electronic structure of Fe nanoparticle-graphene composites and the impact of the interfacial interaction on NH(x) (x = 0, 1, 2, 3) adsorption by first-principles based calculations. We found that Fe(13) nanoparticles can be stabilized by the sp(2) dangling bonds on single vacancy graphene substrate with a binding ...
Shimada Masayuki - - 2012
PROBLEM: The aim of this study was to find immune-related genes expressed in cumulus cells of ovulated cumulus oocyte complexes (COCs) and to clear the functional roles during fertilization process. METHOD OF STUDY: Ovulated COCs were collected from oviduct 16 hr after the hCG injections followed by eCG priming. The cumulus ...
Baeck M - - 2012
BACKGROUND: Although unexpected and paradoxical, allergic hypersensitivity to corticosteroids is a common finding, delayed-type reactions being much more frequently encountered than the immediate-type ones. Although the skin is the main sensitization and elicitation route, other routes, amongst them systemic administration of corticosteroids may exceptionally be involved. OBJECTIVE: To determine the ...
Caetano S L - - 2012
In most studies on beef cattle longevity, only the cows reaching a given number of calvings by a specific age are considered in the analyses. With the aim of evaluating all cows with productive life in herds, taking into consideration the different forms of management on each farm, it was ...
Vunda Aaron - - 2012
A healthy 3-year old boy was brought to the emergency department because of an acutely dilated right pupil, which developed after he had played in the garden. Half an hour before presentation, his parents noticed he had been crying.
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