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Kwon Beom-June - - 2012
Thiazide-type diuretics are the most commonly used blood pressure (BP)-lowering drug for patients with uncomplicated hypertension. However, it has remained unclear whether hydrochlorothiazide (HCTZ) or chlorthalidone (CTD) shows better improvement in central aortic pressure. We conducted an open-label, randomized, prospective cross-over study with an 8-week active treatment (HCTZ of 25 mg ...
Arabaci T - - 2012
Roughness on tooth surfaces is reported to facilitate the reestablishment of microbial dental plaque. Hence, the main goal of dental scaling is to remove bacterial plaque and obtain smoother tooth surfaces. This study was aimed to assess the influence of tip wear of ultrasonic scaler inserts on root surface roughness ...
Kakeri A R - - 2012
Objective: We report an extremely rare case of primary otoscleroma. Method: We present a case report and a review of the world literature concerning otoscleroma. Results: An adult woman presented with chronic suppurative otitis media with tubotympanic disease and conductive hearing loss. On mastoid exploration, dark granulations were seen, which ...
Li Jun - - 2012
Autoimmune cholangitis, Immunoglobulin G4-associated cholangitis (IAC), is a part of multiorgan IgG4-related systemic disease, which was recognized as a new clinicopathological entity in recent years. IAC is defined as a biliary stricture that responds to steroid therapy, frequently is associated with other fibrosing conditions, especially autoimmune pancreatitis and characterized by ...
Ascierto Paolo A - - 2012
To the Editor: Although the efficacy of serine-threonine protein kinase (BRAF) inhibitors has been shown in patients with advanced melanoma who have the V600E BRAF mutation,(1),(2) data on the population with the V600K BRAF mutation are more limited and less encouraging. A phase 2 trial of vemurafenib showed a partial ...
Lutter Chessa K - - 2012
OBJECTIVE: To identify lessons learned from 30 years of implementing the International Code of Marketing of Breast-milk Substitutes ('the Code') and identify lessons learned for the regulation of marketing foods and beverages to children. DESIGN: Historical analysis of 30 years of implementing the Code. SETTING: Latin America and the Caribbean. ...
Mumm Florian - - 2012
A method to fabricate inexpensive and transparent nanowire impalement devices is invented based on CuO nanowire arrays grown by thermal oxidation. By employing a novel process the nanowires are transferred to a transparent, cell-compatible epoxy membrane. Cargo delivery and detailed cell-nanowire interaction studies are performed, revealing that the cell plasma ...
Majeski Elizabeth - - 2012
To determine the feasibility of administering iloprost by inhalation in patients with mild atopic asthma. Volunteers underwent supervised inhalation of iloprost in the clinic with measurement of spirometry and blood pressure for 2 hours. The volunteers then inhaled iloprost four times daily at a dose of 2.5 or 5 μg ...
Lecoindre P - - 2012
A seven-year-old West Highland white terrier was presented for chronic vomiting associated with mild regenerative anaemia and hypoalbuminaemia. Further examination showed a giant polypoid cerebriform mass located in the lesser curvature of the stomach. Partial gastrectomy was performed and histology was consistent with hypertrophic gastritis with typical features of Ménétrier's ...
Cho Heejin - - 2012
The roles of CdS nanocrystals (quantum dots) stabilized by oleic acid ligands in toluene were investigated in the 1,1'-oxalyldiimidazole chemiluminescence (ODI-CL) reaction generated under various environmental conditions. CdS excited by high-energy intermediates formed in ODI-CL reaction emitted dim CL. Also, CdS acted as a catalyst to enhance the yield of ...
Ware James H - - 2012
The statistical consultants to the Journal provide guidance on missing data in reports submitted for publication.
Pravaz Olivier - - 2012
The synthesis via in situ polymerization and characterization of nanocomposites (NCs) made from silica (SiO(2)) nanoparticles in a methyl methacrylate (MMA) monomer matrix is reported. We first investigate the transfer of well-defined spherical silica nanoparticles (NPs) (average radius R = 24.2 ± 3.2 nm) into the monomer solvent. We study ...
Jones Lisa - - 2012
Polycyclic aromatic hydrocarbons (PAHs) are commonly occurring environmental pollutants, 8 of which have been chosen from the list of priority substances in the EU Water Framework Directive (WFD). The levels of PAHs in the environment are affected by a number of emission factors including anthropogenic activities, population equivalents, and weather, ...
- - 2012
To the Editor: Although the efficacy of serine-threonine protein kinase (BRAF) inhibitors has been shown in patients with advanced melanoma who have the V600E BRAF mutation,(1),(2) data on the population with the V600K BRAF mutation are more limited and less encouraging. A phase 2 trial of vemurafenib showed a partial ...
Byeon Jeong-Sik - - 2012
BACKGROUND AND AIM: Performance of double balloon enteroscopy (DBE) on older patients with comorbidities is a matter of safety. We aimed to investigate the utility and safety of DBE in older patients. METHODS: We retrospectively reviewed the medical records of patients 75 years or older who underwent DBE in our ...
Kim Se Hye - - 2012
The self-assembly of small molecules provides a potentially powerful method to create functional nanomaterials for many applications ranging from optoelectronics to oncology. However, the design of well-defined nanostructures via molecular assembly is a highly empirical process, which severely hampers efforts to create functional nanostructures using this method. In this review, ...
Bräutigam Maximilian - - 2012
Resonance Raman microspectroscopy is used to investigate dye-sensitized NiO(x) nanoparticle films to be used as photocathodes in tandem dye-sensitized solar cells. It is shown that rR microspectroscopy has potential for applications in quality assurance in such systems and also in integrated dye-sensitized solar cell modules. Here, ruthenium dye-sensitized NiO(x) nanoparticle ...
Kløverpris Søren - - 2012
The plasma concentration of placentally derived proform of eosinophil major basic protein (proMBP) increases in pregnancy, and three different complexes containing proMBP have been isolated from pregnancy plasma and serum: A 2:2 complex with the metalloproteinase, pregnancy-associated plasma protein-A (PAPP-A), a 2:2 complex with angiotensinogen (AGT), and a 2:2:2 complex ...
Borgmann Silvia H M - - 2012
The present study reports the solid-state properties of Fluvastatin sodium salt crystallized from different solvents for comparison with crystalline forms of the commercially available raw material and United States Pharmacopeia (USP) reference standard. Fluvastatin (FLV) samples were characterized by several techniques; such as X-ray powder diffractometry, differential scanning calorimetry, thermogravimetry, ...
Kim Sungwoo - - 2012
PbS colloidal quantum dot (CQD)-sensitized inorganic-organic heterojunction solar cells fabricated by using the PbS CQDs co-capped by the oleic acid (OA) and 1-dodecanethiol (DT) ligand showed better device stability with aging time under ambient conditions without encapsulation. Furthermore, the device performance is better than the cell fabricated from PbS CQDs ...
Kim Hong K - - 2012
To the Editor: Boyer (July 12 issue)(1) reports that use of naloxone to treat opioid overdose is logical because it is a direct antagonist of mu opioid receptors. Other strategies for treating opioid-induced respiratory depression and oversedation are now plausible and should be developed as alternatives to single-drug therapy with ...
Tranchida Peter Quinto - - 2012
The present manuscript reports a comparative study between conventional and split-flow comprehensive GC×GC-MS. Conventional GC×GC-MS was performed by using a single GC oven, and with a widely employed apolar (30 m × 0.25 mm id)-polar (1 m × 0.10 mm id) column combination. Split-flow GC×GC-MS experiments were carried out by ...
Louwerse Max M - - 2012
Spatial mental representations can be derived from linguistic and non-linguistic sources of information. This study tested whether these representations could be formed from statistical linguistic frequencies of city names, and to what extent participants differed in their performance when they estimated spatial locations from language or maps. In a computational ...
Han Sae-Won - - 2012
The prognostic impact of CpG island methylator phenotype (CIMP) and microsatellite instability (MSI) on the treatment outcome of colon cancer patients receiving adjuvant 5-fluorouracil/ leucovorin/oxaliplatin (FOLFOX) is unclear. We investigated CIMP and MSI status in colorectal cancer patients treated with adjuvant FOLFOX. Stage II and III sporadic colorectal cancer patients ...
Zhang Xinxin - - 2012
The high-pressure crystal structures of the "111" type iron-based superconductors: NaFeAs, LiFeP and LiFeAs have been systematically explored by using particle-swarm structural searches. It was found that though these iron-based superconductors are chemically similar, they adopted distinct structural phase transitions: P4/nmm → Cmcm → P3[combining macron]m1 for NaFeAs, P4/nmm → ...
Winter Shawn S - - 2012
The role of limbic system structures in spatial orientation continues to be debated. The hippocampus (HPC) has been implicated in encoding symbolic representations of environments (i.e., cognitive map), whereas entorhinal cortex (EC) function has been implicated in self-movement cue processing (i.e., dead reckoning). These distinctions largely depend on the electrophysiological ...
Galán Elena - - 2012
The formal [2 + 2] cycloaddition-cycloreversion (CA-CR) between 4-ethynyl-N,N-dimethylaniline and polyenic Donor-π-Acceptor (D-π-A) systems takes place to yield compounds bearing two donors and one acceptor. Structural, linear and second-order nonlinear optical (NLO) properties of the new molecules reveal the stronger polarization of these systems when compared to analogous merocyanines lacking ...
Jamshidi Maral - - 2012
Germ line variation in the TP53 network genes PRKAG2, PPP2R2B, CCNG1, PIAS1 and YWHAQ was previously suggested to have an impact on drug response in vitro. Here, we investigated the effect on breast cancer survival of germ line variation in these genes in 925 Finnish breast cancer patients and further ...
Bellin Milena - - 2012
Worldwide increases in life expectancy have been paralleled by a greater prevalence of chronic and age-associated disorders, particularly of the cardiovascular, neural and metabolic systems. This has not been met by commensurate development of new drugs and therapies, which is in part owing to the difficulty in modelling human diseases ...
Jayasinghe R C - - 2012
The optical properties of p-type InP epitaxial films with different doping concentrations are investigated by infrared absorption measurements accompanied by reflection and transmission spectra taken from 25 to 300 K. A complete dielectric function (DF) model, including intervalence band (IVB) transitions, free-carrier and lattice absorption, is used to determine the optical ...
Hallock Henry L - - 2012
Hippocampal place fields show remapping between environments that contain sufficiently different contextual features, a phenomenon that may reflect a mechanism for episodic memory formation. Previous studies have shown that place fields remap to changes in the configuration of visual landmarks in an environment. Other experiments have demonstrated that remapping can ...
Tsai Ming-Hung - - 2012
BACKGROUND AND AIMS: Acute renal failure (ARF) is a common complication of liver cirrhosis and severe sepsis. Differentiating functional renal failure from acute tubular necrosis (ATN) has been difficult in this clinical setting. It has been shown urinary interleukin 18 (IL-18) can serve as a sensitive marker for ARF and ...
Liao En-Chih - - 2012
A 70-year-old man presented with a 2-month history of pruritus and a sense of fullness in the right ear. There was no hearing impairment, tinnitus, or otorrhea.
Urrechaga E - - 2012
INTRODUCTION: Consequence of the imbalance between the erythroid marrow iron requirements and the actual supply is a reduction in red cell hemoglobin content, which causes hypochromic mature red cells and reticulocytes. Sysmex XE 5000 analyzer (Sysmex Corporation, Kobe, Japan) reports reticulocyte hemoglobin equivalent (Ret-He) and the percentages of erythrocyte subsets, ...
Murray Craig D - - 2012
Purpose: To identify and synthesize qualitative literature on the experience of amputation and prosthesis use for adults, and to make recommendations based on these findings for rehabilitation services. Methods: A systematic search of three databases for qualitative research exploring the experience of amputation and prosthesis use for adults was undertaken. ...
Haneda M - - 2012
BACKGROUND: Pepsinogen (PG) method is widely used to identify high risk group of gastric cancer.It is very useful before Helicobacter pylori (H. pylori) eradication, but after eradication the method becomes useless because PGI, PGII, PGI/II ratio change. Therefore, we aimed to identify for high risk group of gastric cancer using ...
Brinks Ralph - - 2012
This article describes new relationships between the age-specific incidence of, the prevalence of and mortality from a chronic disease. We express these relationships in terms of an ordinary differential equation and form the methodological basis for a novel approach to estimating incidences from age-specific prevalence data. We examine practical aspects ...
Dammak Hichem - - 2012
Molecular dynamics (MD) simulations have been carried out to study isotope effects in lithium hydride and lithium deuteride crystals. Quantum effects on nuclear motion have been included through a quantum thermal bath (QTB). The interatomic forces were described either within the density functional theory (DFT) in the generalized gradient approximation ...
Walsh Jason M - - 2012
DinB is one of two Y family polymerases in E. coli and is involved in copying damaged DNA. DinB is specialized to bypass deoxyguanosine adducts that occur at the N(2) position, with its cognate lesion being the furfuryl adduct. Active site residues have been identified that make contact with the ...
Andreassen Christian Nicolaj - - 2012
Working as a physician at an oncology department has some distinctive characteristics that may lead to a stressful work environment. The present study was conducted to provide a nationwide description of the work conditions of all oncologists in Denmark. By comparing the results of the present study with those of ...
House Jennifer - - 2012
OBJECTIVE: To explore the role of specialist outpatient eating disorders services and investigate how direct access to these affects rates of referral, admissions for inpatient treatment, and continuity of care. METHOD: Services beyond primary care in Greater London retrospectively identified adolescents who presented with an eating disorder over a 2-year ...
Tejedor David - - 2012
The propargyl Claisen rearrangement is a known protocol to gain access to functionalized allenes through the [3,3]-sigmatropic transformation of propargyl vinyl ethers. The correct use of appropriate propargyl vinyl ethers as starting materials coupled with suitable reaction conditions can aid in the development of new domino methodologies in which the ...
Rivera Patricia - - 2012
Diet-induced obesity produces changes in endocannabinoid signaling (ECS), influencing the regulation of energy homeostasis. Recently, we demonstrated that, in high-fat-diet-fed rats, blockade of CB1 receptor by AM251 not only reduced body weight but also increased adult neurogenesis in the hippocampus, suggesting an influence of diet on hippocampal cannabinoid function. To ...
Grey Andrew - - 2012
To the Editor: In a recent pooled analysis of vitamin D dose requirements for fracture prevention, Bischoff-Ferrari and colleagues (July 5 issue)(1) reanalyzed data from clinical trials by taking into account vitamin D supplementation taken by participants in addition to the study medication. This reanalysis provides a more accurate estimation ...
Abdelbary Aly A - - 2012
The aim of this study was to evaluate the effect of the thickness of adsorbed polymer layer (also known as Fixed Aqueous Layer Thickness, FALT) of polymeric stabilizers on zeta potential and stability of nanoparticles in a suspension. Aripiprazole, a poorly water soluble drug was used as a model drug ...
Kim Bo Hyun - - 2012
BACKGROUND AND AIM: As a rare liver disease, little is known about autoimmune hepatitis (AIH). This study investigated the clinical features and compared two diagnostic criteria of AIH in Korea. METHODS: A nationwide, multicenter, retrospective analysis was done of data of adult patients diagnosed with AIH from January 2005 to ...
Guan Zhenping - - 2012
We have demonstrated that cysteine and glutathione induced edge-to-edge coupling of Au NCs, which caused a band selective enhancement of two-photon photoluminescence. The intensity of X band of photoluminescence of Au NCs was found to be enhanced up to 60-fold and 46-fold upon addition of cysteine and glutathione respectively, while ...
Joh Jennifer E - - 2012
  Neo-adjuvant chemotherapy is used for locally advanced breast cancer patients with significant variation in tumor response. Our objective is to determine the clinicopathologic effect of neo-adjuvant chemotherapy on invasive lobular carcinoma. A review of a single-institution data base of women diagnosed with breast cancer identified 30 patients from 1999 ...
Throckmorton Douglas C - - 2012
To the Editor: Boyer (July 12 issue)(1) reports that use of naloxone to treat opioid overdose is logical because it is a direct antagonist of mu opioid receptors. Other strategies for treating opioid-induced respiratory depression and oversedation are now plausible and should be developed as alternatives to single-drug therapy with ...
Chen Yang - - 2012
The present study attempted to test the postulate that sounds of a foreign language that are familiar can be produced with less accuracy than sounds that are new to second language (L2) learners. The first two formant frequencies (F1 and F2) were obtained from the 11 English monophthong vowels produced ...
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