Search Results
Results 251 - 300 of 3179
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Smith Catherine M - - 2012
Purpose: The aim of this study was to investigate experiences of participating in a feasibility trial of a novel physiotherapy intervention (Blue Prescription). The trial was designed to increase participation in physical activity for people with multiple sclerosis living in the community. Methods: We individually interviewed 27 volunteers from two ...
Witte Christopher - - 2012
Increasing the sensitivity of NMR experiments is an ongoing field of research to help realise the exquisite molecular specificity of this technique. Hyperpolarisation of various nuclei is a powerful approach that enables the use of NMR for molecular and cellular imaging. Substantial progress has been achieved over recent years in ...
Li Ying - - 2012
A novel surface-enhanced Raman scattering (SERS) assay is demonstrated by developing a cross strand-displacement amplification (CSDA) method to enhance the SERS signals. Highly sensitive and selective detection of any single-stranded DNA is achieved and an aptasensor for proteins is constructed.
Echard Arnaud - - 2012
The ESCRT (endosomal sorting complex required for transport) machinery is responsible for scission of the cytokinetic bridge that connects daughter cells at the end of mitosis. Specific endosomes are now found to mediate local bridge constriction and actin clearance in human cells, which contribute to the recruitment of ESCRT components ...
Chen G-C - - 2012
Epidemiologic studies have suggested that magnesium intake may be associated with a decreased risk of colorectal cancer (CRC), but the findings have been inconsistent. We aimed to assess this association by conducting a meta-analysis of prospective studies. We performed a literature search on PubMed database through July 2012 to identify ...
de Almeida Natália E C - - 2012
Lupulones, hops β-acids, are one of the main constituents of the hops resin and have an important contribution to the overall bacteriostatic activity of hops during beer brewing. The use of lupulones as natural alternatives to antibiotics is increasing in the food industry and also in the bio-ethanol production. However, ...
Abbès Samir - - 2012
Aflatoxin M(1) (AFM(1)) has been detected in many parts of the world both in raw milk and many dairy products, causing great economic losses and human disease. Unfortunately, there are few studies dealing with AFM(1) immunotoxicity/interactions with lactic acid bacteria for potential application as a natural preventive agent. The aim ...
Winter Heidi - - 2012
ABSTRACT Background: Globally, falls in older people are a leading cause of injury-related mortality and morbidity. Cognitive impairment is a well-known risk factor for falls in this population group. While there is now a large body of evidence to support effective interventions for falls reduction across care settings, very little ...
Johnson Bryce E - - 2012
Effective collection of trace-level lanthanides and actinides is advantageous for recovery and recycling of valuable resources, environmental remediation, chemical separations, and in situ monitoring. Using isotopic tracers, we have evaluated a number of conventional and nanoporous sorbent materials for their ability to capture and remove selected lanthanides (Ce and Eu) ...
Rogers Benedict A - - 2012
Preoperative planning is essential to define anatomy, clarify the operative approach and exposure, and ensure that suitable implants are available.Concerns exist regarding the long-term effectiveness and safety of hip resurfacing arthroplasty for the young dysplastic hip.In light of current evidence, concerns exist regarding the use of metal-on-metal articulations for hip ...
Shah Sanjiv J - - 2012
Pulmonary hypertension (PH), defined as elevated pulmonary artery pressure, is common in the general population and associated with increased mortality. Accordingly, physicians commonly encounter patients with dyspnea, exercise intolerance, and/or right heart failure who have elevated pulmonary artery systolic pressure (PASP) on echocardiography. Although pulmonary arterial vasodilators may often be ...
Lazić P - - 2012
Density functional theory (DFT) has been steadily improving over the past few decades, becoming the standard tool for electronic structure calculations. The early local functionals (LDA) were eventually replaced by more accurate semilocal functionals (GGA) which are in use today. A major persisting drawback is the lack of the nonlocal ...
Dominguez P L - - 2012
Background  Depression is a common mental health condition that has been associated with psoriasis. In the absence of prospective data, it remains unclear whether depression precedes psoriasis as a risk factor. Objectives  To examine the association between depression and the risk of new-onset psoriasis. Methods  A prospective cohort of 86 ...
Davies James E - - 2012
Aim This study aims to evaluate changes in the durations of English National Health Service prescriptions, as indicated by the volumes of unit doses supplied between 1998 and 2009, and consider relevant policy implications. BACKGROUND: Around the world, countries are seeking to manage the increase in medicines prescribing. In England, ...
Miller Robert A - - 2012
Abstract Objective: To compare the changes in incisor inclination between two compliance-free Class II correction protocols for the treatment of mild to moderate Class II malocclusions. Materials and Methods: Among Class II malocclusion patients a total of 38 consecutive patients treated with the Xbow appliance and later with full brackets ...
Baynam Gareth - - 2012
Three-dimensional (3D) facial analysis is ideal for high-resolution, nonionizing, noninvasive objective, high-throughput phenotypic, and phenomic studies. It is a natural complement to (epi)genetic technologies to facilitate advances in the understanding of rare and common diseases. The face is uniquely reflective of the primordial tissues, and there is evidence supporting the ...
Gupta Madhulika A - - 2012
Abstract INTRODUCTION: Acne can be associated with psychiatric morbidity and suicide, which have been sometimes considered an adverse reaction to some acne therapies. A recent population-based study reports that suicide in acne is related to the psychosocial burden of substantial acne, rather medication effects. As suicidality is not always directly ...
Sergeeva Alina P - - 2012
Clusters of boron atoms exhibit intriguing size-dependent structures and chemical bonding that are different from bulk boron and may lead to new boron-based nanostructures. We report a combined photoelectron spectroscopic and ab initio study of the 22- and 23-atom boron clusters. The joint experimental and theoretical investigation shows that B22- ...
Xu Xuan - - 2012
We report here a catalyst made of Pd nanoparticles supported on a mesoporous N-doped carbon, Pd@CN0.132, which was shown to be highly active and promoted the biomass refining. Using task-specific ionic liquid (3-methyl-1-butylpyridine dicyanamide) as precursor and silica nanoparticles as hard template, high nitrogen (12 wt%) con-tent, mesoporous carbon material ...
Haqq-Misra Jacob - - 2012
Abstract Proposals to address present-day global warming through the large-scale application of technology to the climate system, known as geoengineering, raise questions of environmental ethics relevant to the broader issue of planetary engineering. These questions have also arisen in the scientific literature as discussions of how to terraform a planet ...
Larsen Martin M - - 2012
Analyses of lead (Pb) isotopes have been performed in terrestrial and fresh water environments to estimate historical uses of leaded fuel, but so far this method has not been employed in studies of world-wide marine surface sediments. We analyzed Pb and its isotopes in 23 surface sediments from four continents ...
Li Q - - 2012
The hydrogen-methane compound (H(2))(4)CH(4)-or for short H4M-is one of the most promising hydrogen-storage materials. This van der Waals compound is extremely rich in molecular hydrogen: 33.3 mass%, not including the hydrogen bound in CH(4); including it, we reach even 50.2 mass%. Unfortunately, H4M is not stable under ambient pressure and temperature, requiring ...
Yang Hui-Yu - - 2012
Angiotensin-(1-7) (Ang-(1-7)), a metabolite of angiotensin I and angiotensin II (Ang II), is a counterregulatory mediator of Ang II. Here, we investigated the effects of Ang-(1-7) on Ang II-induced apoptosis in human umbilical vein endothelial cells (HUVECs). Acridine orange/ethidium bromide (AO/EB) staining and propidium iodide (PI) staining were used to ...
Konieczny Markus R - - 2012
The appropriate treatment of dens fractures is unclear. We established a staged treatment protocol for dens fractures and conducted a prospective study to evaluate the outcome of treatment based on this protocol. We prospectively evaluated sixty-nine consecutive patients who presented to our institution with a dens fracture. The mean duration ...
Madden Ros - - 2012
Purpose: This paper seeks to contribute to thoughtful description, recording and measurement of functioning, by discussing some fundamental questions to consider before starting, framed as: why, what, how and who. Method: Generic literature on measurement methods and the more specialised literature on application of the ICF over the last decade ...
Schaak Raymond E - - 2012
Colloidal hybrid nanoparticles merge multiple distinct materials into single particles, producing nanostructures that often exhibit synergistic properties and multifunctionality. As the complexity of such nanostructures continues to expand and the design criteria become increasingly stringent, the synthetic pathways required to access such materials are growing in sophistication. Multistep pathways are ...
Elcin Gonca - - 2012
Abstract Background: Narrowband ultraviolet B (UVB) provides complete response (CR) in 54 to 91% of early mycosis fungoides (MF) patients. Data concerning relapse rate and relapse-free interval after discontinuation of therapy need clarification. The purpose of this study was to evaluate the relapse rate and the relapse-free intervals of early ...
Annen Samuel P - - 2012
Acids, esters and amides have to date been the only isolated products from the dehydrogenation of primary alcohols with [Rh(trop(2)N)(L)] (trop = 5-H-dibenzo[a,d]cyclohepten-5yl) type complexes. With the reported method the available product family is finally to aldehydes. Using nitrosobenzene as a hydrogen acceptor the aldehydes could be isolated in up ...
Szlachetko Jakub - - 2012
We report on the decomposition of platinum acetylacetonate (Pt(acac)(2)) in hydrogen induced by flash heating. The changes in the local Pt structure were followed by high energy resolution off-resonant spectroscopy uniquely performed with sub-second time resolution. The decomposition consists of a two-step reduction process of the Pt(ii) species.
Obi D - - 2012
We report on the elastic and piezoresistive properties of individual epitaxial Si-NWs grown on n-doped Si(111) by pulsed laser deposition. Using scanning probe microscopy, we obtained a Young's modulus between 82 and 900 GPa for the nanowires, unaffected by the nanowire shape. A relative resistivity change is observed in the prestrained ...
Stevens Sara A - - 2012
Background: Children with fetal alcohol spectrum disorders (FASD) exhibit difficulties in many cognitive and behavioral domains and also have high comorbidity with other disorders such as attention deficit/hyperactivity disorder (ADHD) and conduct disorder as well as autism. Although the FASD profile is shown to be distinct from ADHD and conduct ...
Mason Rose A - - 2012
Introduction: Empirical support regarding effective interventions for individuals with autism spectrum disorder (ASD) within a postsecondary community is limited. Video modeling, an empirically supported intervention for children and adolescents with ASD, may prove effective in addressing the needs of individuals with ASD in higher education. Objective: This study evaluated the ...
Bainbridge Lesley - - 2012
This is the second paper in a two-part series. The first paper presented a study that provided a more contextual description of the commonly applied definition of interprofessional education (IPE) offered in 2002 by the Centre for the Advancement of Interprofessional Education (CAIPE) in the UK. The study's results confirm ...
Moellmann Jonas - - 2012
The structures and relative energies of the three naturally occurring modifications of titanium dioxide (rutile, brookite and anatase) were investigated. For an accurate description, atom-pairwise dispersion-corrected density functional theory (DFT-D) was applied. The DFT-D3 scheme was extended non-empirically to improve the description of Ti atoms in bulk systems. New dispersion ...
Sarisozen Can - - 2012
Overexpression of drug efflux pump P-gp is one of the major reasons to cause multidrug resistance (MDR). To overcome P-gp mediated MDR, modulators, so called P-gp inhibitors, can be used to block efflux pump activity. Elacridar is one of the most potent P-gp inhibitors, which can cause irreversible and total ...
Yanikkerem Emre - - 2012
AIMS AND OBJECTIVES: To determine awareness, use and attitudes of Turkish women towards prenatal screening tests (PST) for Down syndrome (DS). BACKGROUND: The technology of screening and diagnosing congenital diseases and abnormalities of foetuses has rapidly developed in the past few decades and prenatal screening for DS in early pregnancy ...
Hubbs Jed L - - 2012
A series of triterpene-based gamma-secretase modulators is optimized. An acetate present at the C24 position of the natural product was replaced with either carbamates or ethers to provide compounds with better metabolic stability. With one of those pharmacophores in place at C24, morpholines or carbamates were installed at the C3 ...
Kamel Amin - - 2012
The metabolism of elzasonan has been examined in vitro using hepatic microsomes from human and recombinant heterologously expressed P450 enzymes (rCYP). Metabolism occurs primarily via oxidative N-demethylation to form M4 and oxidation reactions to form elzasonan N-oxide (M5) and 5-hydroxyelzasonan metabolite (M3). Additionally, elzasonan was shown to be metabolized to ...
Ouyang L - - 2012
Programmed cell death (PCD), referring to apoptosis, autophagy and programmed necrosis, is proposed to be death of a cell in any pathological format, when mediated by an intracellular program. These three forms of PCD may jointly decide the fate of cells of malignant neoplasms; apoptosis and programmed necrosis invariably contribute ...
Kuntzer T - - 2012
In diabetes mellitus, it is expected to see a common, mainly sensitive, distal symmetrical polyneuropathy (DPN) involving a large proportion of diabetic patients according to known risk factors. Several other diabetic peripheral neuropathies are recognized, such as dysautonomia and multifocal neuropathies including lumbosacral radiculoplexus and oculomotor palsies. In this review, ...
Walker M - - 2012
A quartz crystal microbalance (QCM) with a graphene/Ni(111) electrode has been used to probe frictional heating effects in Kr monolayers sliding on the microbalance electrode in response to its oscillatory motion. The temperatures of the sliding Kr monolayers are observed to rise approximately 13 K higher than their static counterparts, but ...
Chiesa O A - - 2012
This study is part of an ongoing effort to develop animal models that provide milk and sufficient infant (offspring) plasma samples to fully describe a drug's pharmacokinetics to quantitate the risk to the nursing infant. Ciprofloxacin was administered to six healthy Holstein cows as a constant rate intravenous infusion (flow ...
Bogas J Alexandre - - 2012
This article presents a detailed study of the microstructure of Iberian expanded clay lightweight aggregates (LWA). Other than more commonly used mercury porosimetry (MP) and water absorption methods, the experimental study involves optical microscopy, scanning electron microscopy (SEM), and microtomography (μ-CT). Pore connectivity and how it is deployed are shown ...
Bisschoff Izak J - - 2012
OFD1, now recognized as a ciliopathy, is characterized by malformations of the face, oral cavity and digits, and is transmitted as an X-linked condition with lethality in males. Mutations in OFD1 also cause X-linked Joubert syndrome (JBTS10) and Simpson-Golabi-Behmel syndrome type 2 (SGBS2). We have studied 55 sporadic and six ...
Le Duy - - 2012
The physisorption of the nucleobases adenine (A), cytosine (C), guanine (G), thymine (T), and uracil (U) on graphene is studied using several variants of the density functional theory (DFT): the generalized gradient approximation with the inclusion of van der Waals interaction (vdW) based on the TS approach (Tkatchenko and Scheffer ...
Phelps James R - - 2012
Successful mood stabilizing treatments reduce intracellular sodium in an activity-dependent manner. This can also be achieved with acidification of the blood, as is the case with the ketogenic diet. Two women with type II bipolar disorder were able to maintain ketosis for prolonged periods of time (2 and 3 years, ...
Zanna H - - 2012
Cytosine deaminase (CD) from Aspergillus parasiticus, which has half-life of 1.10 h at 37°C, was stabilized by immobilization on calcium alginate beads. The immobilized CD had pH and temperature optimum of 5 and 50°C respectively. The immobilized enzyme also stoichiometrically deaminated Cytosine and 5-fluorocytosine (5-FC) with the apparent K(M) values of ...
Sherlaw William - - 2012
To understand the French public's response to the 2009 pandemic A/H1N1 influenza health threat a sequence analysis framework has been employed mobilising different theoretical strands such as innovations diffusion theory, surprise theory and social representation theory. These tend to suggest that disease episodes, public health policy and the public's response ...
Den Hertog Martien Ilse - - 2012
GaN nanowires (NWs) with an AlN insertion were studied by correlated optoelectronic and aberration-corrected scanning transmission electron microscopy (STEM) characterization on the same single NW. Using aberration-corrected annular bright field and high angle annular dark field STEM, we identify the NW growth axis to be the N-polar [000-1] direction. The ...
Hanson Lindsey - - 2012
Vertically aligned nanopillars can serve as excellent electrical, optical and mechanical platforms for biological studies. However, revealing the nature of the interface between the cell and the nanopillar is very challenging. In particular, a matter of debate is whether the cell membrane remains intact around the nanopillar. Here we present ...
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