Search Results
Results 201 - 250 of 3178
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Mason Rose A - - 2012
Introduction: Empirical support regarding effective interventions for individuals with autism spectrum disorder (ASD) within a postsecondary community is limited. Video modeling, an empirically supported intervention for children and adolescents with ASD, may prove effective in addressing the needs of individuals with ASD in higher education. Objective: This study evaluated the ...
Bainbridge Lesley - - 2012
This is the second paper in a two-part series. The first paper presented a study that provided a more contextual description of the commonly applied definition of interprofessional education (IPE) offered in 2002 by the Centre for the Advancement of Interprofessional Education (CAIPE) in the UK. The study's results confirm ...
Tsampalieros Anne A Department of Pediatrics, Children's Hospital of Eastern Ontario, University of Ottawa, Ottawa, Ontario, - - 2013
The impact of pediatric chronic kidney disease (CKD) on acquisition of volumetric bone mineral density (BMD) and cortical dimensions is lacking. To address this issue, we obtained tibia quantitative computed tomography scans from 103 patients aged 5-21 years with CKD (26 on dialysis) at baseline and 12 months later. Gender, ...
Moellmann Jonas - - 2012
The structures and relative energies of the three naturally occurring modifications of titanium dioxide (rutile, brookite and anatase) were investigated. For an accurate description, atom-pairwise dispersion-corrected density functional theory (DFT-D) was applied. The DFT-D3 scheme was extended non-empirically to improve the description of Ti atoms in bulk systems. New dispersion ...
Sarisozen Can - - 2012
Overexpression of drug efflux pump P-gp is one of the major reasons to cause multidrug resistance (MDR). To overcome P-gp mediated MDR, modulators, so called P-gp inhibitors, can be used to block efflux pump activity. Elacridar is one of the most potent P-gp inhibitors, which can cause irreversible and total ...
Yanikkerem Emre - - 2012
AIMS AND OBJECTIVES: To determine awareness, use and attitudes of Turkish women towards prenatal screening tests (PST) for Down syndrome (DS). BACKGROUND: The technology of screening and diagnosing congenital diseases and abnormalities of foetuses has rapidly developed in the past few decades and prenatal screening for DS in early pregnancy ...
Kruse L M LM Department of Orthopedic Surgery, Washington University School of Medicine, 660 South Euclid Avenue, Campus Box 8233, St. Louis, MO 63110, - - 2012
Rigorous rehabilitation after anterior cruciate ligament (ACL) reconstruction is necessary for a successful surgical outcome. A large number of clinical trials continue to assess aspects of this rehabilitation process. Prior systematic reviews evaluated fifty-four Level-I and II clinical trials published through 2005. Eighty-five articles from 2006 to 2010 were identified ...
Jain-Gupta Neeta - - 2012
Brucellosis is the most common zoonotic disease worldwide and there is no vaccine for human use. Brucella melitensis Rev1, a live attenuated strain, is the commercial vaccine for small ruminants to prevent B. melitensis infections but has been associated with abortions in animals. Moreover, strain Rev1 is known to cause ...
Lee D H DH Department of Dermatology, Seoul National University College of Medicine, Institute of Human-Environment Interface Biology, Seoul National University, Seoul, - - 2013
Optimum dose ratios of rimabotulinumtoxinB (BTX-B) and onabotulinumtoxinA (BTX-A) have not been determined for forehead wrinkles. To compare the efficacy and safety of BTX-B and BTX-A for the treatment of forehead lines. Twenty-two women (mean age, 40 years) with symmetrical moderate to severe forehead lines were randomized to receive single ...
Létourneau Mathieu - - 2012
Manganese oxide (MnO) nanoparticles have been suggested as a promising "positive" MRI contrast agent for cellular and molecular studies. Mn-based contrast agents could enable T(1)-weighted quantitative cell tracking procedures in vivo, based on signal enhancement. In this study, ultra-small MnO particles were synthesized and coated with thiolated molecules (DMSA) and ...
Gallotti Roberto - - 2012
Neonatal aortic thrombosis is a potentially life-threatening condition with significant morbidity and mortality if undiagnosed and untreated. The most common location of arterial thrombosis in neonates is in the abdominal aorta and is associated with umbilical artery catheterisation. There are only a few previous reports of thrombosis in the ascending ...
Zhang Xiqi - - 2012
A series of remarkable multifunctional 9,10-distyrylanthracene derivatives (, n = 7-12) was synthesized. All derivatives possess typical aggregation-induced emission (AIE) property. Some of the derivatives exhibit multifunctional properties, including AIE, mechanofluorochromism, vapochromism, thermochromism, and mesomorphism, which are rarely found to exist simultaneously in a single compound.
Chew Wee-Siong - - 2012
Context: Increased use of engineered nanoparticles may result in exposure of workers and consumers, making them a health concern. Objective: To identify potential blood miRNA biomarkers after intravenous gold nanoparticle (AuNP) exposure. Materials and methods: miRNA microarray analysis was carried out on blood of rats at 1 week and 2 ...
Murphy Elizabeth Carmel - - 2012
Among the Gram-positive anaerobic bacteria associated with clinical infections, the Gram-positive anaerobic cocci (GPAC) are the most prominent and account for approximately 25-30% of all isolated anaerobic bacteria from clinical specimens. Still, routine culture and identification of these slowly growing anaerobes to the species level has been limited in the ...
Morin Jean-Paul - - 2012
1. We review the specific approaches for lung tissue slices preparation and incubation systems and the research application fields in which lung slices proved to be a very efficient alternative to animal experimentation for biomechanical, physiological, pharmacological and toxicological approaches. 2. Focus is made on air-liquid interface dynamic organ culture systems that ...
Deshmukh-Taskar Priya - - 2012
OBJECTIVE: To examine the association between breakfast skipping and type of breakfast consumed with overweight/obesity, abdominal obesity, other cardiometabolic risk factors and the metabolic syndrome (MetS). DESIGN: Cross-sectional. Three breakfast groups were identified, breakfast skippers (BS), ready-to-eat-cereal (RTEC) consumers and other breakfast (OB) consumers, using a 24 h dietary recall. ...
Capo-Chichi José-Mario - - 2012
Mutations in the gene encoding the iron-sulfur-containing DNA helicase DDX11 (ChlR1) were recently identified as a cause of a new recessive cohesinopathy Warsaw breakage syndrome (WABS), in a single patient with severe microcephaly, pre- and postnatal growth retardation, and abnormal skin pigmentation. Here, using homozygosity mapping in a Lebanese consanguineous ...
Song He H Department of Chemistry, Mississippi State University, Mississippi State, Mississippi 39762, - - 2012
Carbonic anhydrase (CA, general abbreviation for human carbonic anhydrase II) is a well-studied, zinc-dependent metalloenzyme that catalyzes hydrolysis of carbon dioxide to the bicarbonate ion. The apo-form of CA (apoCA, CA where Zn(2+) ion has been removed) is relatively easy to generate, and reconstitution of the human erythrocyte CA has ...
Ishizuka Takumi - - 2012
Toward new biotechnology by genetic alphabet expansion, we developed an efficient site-specific labeling method for large RNA molecules. The combination of unnatural base pair transcription and post-transcriptional modification by click chemistry enables simple RNA labeling with a wide variety of functional groups at desired positions, in a one-pot reaction.
Fang Jingjing - - 2012
A metabolic profiling study was carried out on rapeseed (Brassica napus L.). Eleven glucosinolates were identified by high-performance liquid chromatography (HPLC) coupled with diode array detection (DAD) and mass spectrometry (MS). Additionally, 18 phenolic compounds were profiled from an ethanol extract of rapeseed. Beside two major phenols, sinapine and methyl ...
Mesch Gustavo S - - 2012
This paper examines the relationship between attention to the mass media and concern about becoming infected with H1N1 in two nationwide random samples interviewed during the flu epidemic of 2009. The first sample (N = 1004) was taken at the end of the first wave of the outbreak in the US and ...
Donaldson D S - - 2012
The B subunit of E. coli heat-labile enterotoxin (EtxB) protects against the development of T helper type 1 (Th1)-mediated autoimmune pathologies in mice. Protection was transferable with splenic CD4(+) T cells and was less effective following CD25 depletion; implying a T regulatory cell (Treg)-mediated process. We hypothesized that if this ...
Stam Mette K - - 2012
An MRI-linac system provides direct MRI feedback and with that the possibility of adapting radiation treatments to the actual tumour position. This paper addresses the use of fast 1D MRI, pencil-beam navigators, for this feedback. The accuracy of using navigators was determined on a moving phantom. The possibility of organ ...
Bangalore Sripal S Cardiovascular Clinical Research Center, New York University School of Medicine, 550 First Ave, New York, NY 10016, USA. - - 2012
β-Blockers remain the standard of care after a myocardial infarction (MI). However, the benefit of β-blocker use in patients with coronary artery disease (CAD) but no history of MI, those with a remote history of MI, and those with only risk factors for CAD is unclear. To assess the association ...
Dumantepe Mert M Department of Cardiovascular Surgery, Memorial Atasehir Hospital, Istanbul, Turkey. - - 2012
To evaluate the efficacy of endovenous laser ablation (EVLA) of incompetent perforating veins (IPVs) with 1470 nm laser with 400 μm radial fiber. EVLA for perforating veins can be performed with insignificant postprocedural morbidity. This allows treatment to be offered to elderly patients with comorbidities that would preclude anesthesia for surgical treatment ...
Lau Rosanna - - 2012
Cellular inhibitor of apoptosis proteins (cIAP1 and cIAP2) function to prevent apoptosis and are often overexpressed in various cancers. However, mutations in cIAP1/2 can activate the alternative NFκB pathway through IκBα-kinase-α (IKKα) and are associated with hematopoetic malignancies. In the current study, we found that knockdown of cIAP2 in human ...
Milošev Ingrid - - 2012
To improve the long-term performance of hip prostheses, alternative bearings with metal-on-metal (MoM) and ceramic-on-ceramic (CoC) couples have been introduced. Although currently the results from the use of these bearings are in the midterm stage, there have been few comparative studies of these different bearings. From 2000 to 2002, 487 ...
Björkman T - - 2012
We apply a range of density-functional-theory-based methods capable of describing van der Waals interactions with weakly bonded layered solids in order to investigate their accuracy for extended systems. The methods under investigation are the local-density approximation, semi-empirical force fields, non-local van der Waals density functionals and the random-phase approximation. We ...
Zanna H - - 2012
Cytosine deaminase (CD) from Aspergillus parasiticus, which has half-life of 1.10 h at 37°C, was stabilized by immobilization on calcium alginate beads. The immobilized CD had pH and temperature optimum of 5 and 50°C respectively. The immobilized enzyme also stoichiometrically deaminated Cytosine and 5-fluorocytosine (5-FC) with the apparent K(M) values of ...
Sherlaw William - - 2012
To understand the French public's response to the 2009 pandemic A/H1N1 influenza health threat a sequence analysis framework has been employed mobilising different theoretical strands such as innovations diffusion theory, surprise theory and social representation theory. These tend to suggest that disease episodes, public health policy and the public's response ...
Den Hertog Martien Ilse - - 2012
GaN nanowires (NWs) with an AlN insertion were studied by correlated optoelectronic and aberration-corrected scanning transmission electron microscopy (STEM) characterization on the same single NW. Using aberration-corrected annular bright field and high angle annular dark field STEM, we identify the NW growth axis to be the N-polar [000-1] direction. The ...
Hanson Lindsey - - 2012
Vertically aligned nanopillars can serve as excellent electrical, optical and mechanical platforms for biological studies. However, revealing the nature of the interface between the cell and the nanopillar is very challenging. In particular, a matter of debate is whether the cell membrane remains intact around the nanopillar. Here we present ...
Rogers Benedict A - - 2012
Preoperative planning is essential to define anatomy, clarify the operative approach and exposure, and ensure that suitable implants are available.Concerns exist regarding the long-term effectiveness and safety of hip resurfacing arthroplasty for the young dysplastic hip.In light of current evidence, concerns exist regarding the use of metal-on-metal articulations for hip ...
Shah Sanjiv J SJ Division of Cardiology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois 60611, USA. - - 2012
Pulmonary hypertension (PH), defined as elevated pulmonary artery pressure, is common in the general population and associated with increased mortality. Accordingly, physicians commonly encounter patients with dyspnea, exercise intolerance, and/or right heart failure who have elevated pulmonary artery systolic pressure (PASP) on echocardiography. Although pulmonary arterial vasodilators may often be ...
Lazić P - - 2012
Density functional theory (DFT) has been steadily improving over the past few decades, becoming the standard tool for electronic structure calculations. The early local functionals (LDA) were eventually replaced by more accurate semilocal functionals (GGA) which are in use today. A major persisting drawback is the lack of the nonlocal ...
Dominguez P L PL Department of Dermatology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, - - 2013
Depression is a common mental health condition that has been associated with psoriasis. In the absence of prospective data, it remains unclear whether depression precedes psoriasis as a risk factor. To examine the association between depression and the risk of new-onset psoriasis. A prospective cohort of 86 880 US female ...
Davies James E - - 2012
Aim This study aims to evaluate changes in the durations of English National Health Service prescriptions, as indicated by the volumes of unit doses supplied between 1998 and 2009, and consider relevant policy implications. BACKGROUND: Around the world, countries are seeking to manage the increase in medicines prescribing. In England, ...
Miller Robert A - - 2012
Abstract Objective: To compare the changes in incisor inclination between two compliance-free Class II correction protocols for the treatment of mild to moderate Class II malocclusions. Materials and Methods: Among Class II malocclusion patients a total of 38 consecutive patients treated with the Xbow appliance and later with full brackets ...
Baynam Gareth - - 2012
Three-dimensional (3D) facial analysis is ideal for high-resolution, nonionizing, noninvasive objective, high-throughput phenotypic, and phenomic studies. It is a natural complement to (epi)genetic technologies to facilitate advances in the understanding of rare and common diseases. The face is uniquely reflective of the primordial tissues, and there is evidence supporting the ...
Gupta Madhulika A - - 2012
Abstract INTRODUCTION: Acne can be associated with psychiatric morbidity and suicide, which have been sometimes considered an adverse reaction to some acne therapies. A recent population-based study reports that suicide in acne is related to the psychosocial burden of substantial acne, rather medication effects. As suicidality is not always directly ...
Sergeeva Alina P - - 2012
Clusters of boron atoms exhibit intriguing size-dependent structures and chemical bonding that are different from bulk boron and may lead to new boron-based nanostructures. We report a combined photoelectron spectroscopic and ab initio study of the 22- and 23-atom boron clusters. The joint experimental and theoretical investigation shows that B22- ...
Xu Xuan - - 2012
We report here a catalyst made of Pd nanoparticles supported on a mesoporous N-doped carbon, Pd@CN0.132, which was shown to be highly active and promoted the biomass refining. Using task-specific ionic liquid (3-methyl-1-butylpyridine dicyanamide) as precursor and silica nanoparticles as hard template, high nitrogen (12 wt%) con-tent, mesoporous carbon material ...
Rietjens Saskia J - - 2012
Clinical outcome following 3,4-methylenedioxymethamphetamine (MDMA) intake ranges from mild entactogenic effects to a life-threatening intoxication. Despite ongoing research, the clinically most relevant mechanisms causing acute MDMA-induced adverse effects remain largely unclear. This complicates the triage and treatment of MDMA users needing medical care. The user's genetic profile and interactions resulting ...
Arélin Maria M Institute of Human Genetics, Charité University Medicine Berlin, Berlin, - - 2013
Genome-wide linkage analysis is an established tool to map inherited diseases. To our knowledge it has not been used in prenatal diagnostics of any genetic disorder. We present a family with a severe recessive mental retardation syndrome, where the mother wished pregnancy termination to avoid delivering another affected child. By ...
Azulai Daniel - - 2012
Gold /silver nanowires of controlled diameter were synthesized from catalytic metal seed particles at the substrate/solution interface. Small seed nanoparticles of three different sizes: ~1 nm (11 gold atoms), ~1.4 nm (~55 gold atoms), and homemade nanoparticles of ~2 nm were used. By varying a single type of seed particle ...
Caciuc Vasile - - 2012
We have performed a systematic semi-empirical and ab initio van der Waals study to investigate the bonding mechanism of benzene (C(6)H(6)), triazine (C(3)N(3)H(3)) and borazine (B(3)N(3)H(6)) adsorbed on graphene and a single boron nitride (BN) sheet. The two semi-empirical approaches used to include the van der Waals (vdW) interactions in ...
Mimiaga Matthew J - - 2012
Crystal methamphetamine use is a major driver behind high-risk sexual behavior among men who have sex with men (MSM). Prior work suggests a cycle of continued crystal methamphetamine use and high-risk sex due to loss of the ability to enjoy other activities, which appears to be a side effect of ...
Lynch Danielle C - - 2012
Acrodysostosis is characterized by nasal hypoplasia, peripheral dysostosis, variable short stature, and intellectual impairment. Recently, mutations in PRKAR1A were reported in patients with acrodysostosis and hormone resistance. Subsequently, mutations in a phosphodiesterase gene (PDE4D) were identified in seven sporadic cases. We sequenced PDE4D in seven acrodysostosis patients from five families. ...
Sabo Marlis T - - 2012
The reference points for rotational orientation of the humeral component during elbow arthroplasty typically are on the articular surface or the humeral epicondyles. With bone loss, these landmarks may be compromised. Our purpose was to assess whether the flat posterior humeral cortex proximal to the olecranon fossa is a reliable ...
Murdoch David R DR Department of Pathology, University of Otago, Christchurch, PO Box 4345, Christchurch 8011, New Zealand. - - 2012
Observational studies have reported an inverse association between serum 25-hydroxyvitamin D (25-OHD) levels and incidence of upper respiratory tract infections (URTIs). However, results of clinical trials of vitamin D supplementation have been inconclusive. To determine the effect of vitamin D supplementation on incidence and severity of URTIs in healthy adults. ...
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