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Results 201 - 250 of 3179
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Wang Hung-Jen - - 2012
Chronic renal failure is a devastating disease that leads to a multitude of complications. Cell therapy has emerged as a potential treatment modality for renal failure. However, efficacy testing on systemic renal function has been challenging due to the limited availability of reliable models that are fully characterized. In this ...
Skelley Nathan W - - 2012
Since the 1910 Flexner Report, medical education continues to undergo curriculum and graduation guideline reform to meet the needs of physicians and patients. Our aims were to (1) assess the quality of musculoskeletal education at our institution's School of Medicine by reporting the results of the Freedman and Bernstein examination ...
Hanke Felix - - 2012
We have investigated the performance of popular density functionals that include van der Waals interactions for the experimentally well-characterized problem of ethene (C(2)H(4)) adsorbed on the low-index surfaces of copper. This set of functionals does not only include three van der Waals density functionals-vdwDF-PBE, vdwDF-revPBE and optB86b-vdwDF-and two dispersion-corrected functionals-Grimme and TS-but ...
Hahm Myung Gwan - - 2012
Here, we design and develop high-power electric double-layer capacitors (EDLC) using carbon based dimensional (3D) hybrid nanostructured electrodes. 3D hybrid nanostructured electrodes consist of vertically aligned carbon nanotubes (CNT) on highly porous carbon nanocups (CNC) were synthesized by combination of anodization and chemical vapor deposition techniques. 3D electrode based supercapacitor ...
Pereira Raquel - - 2012
A SAR study has been carried out around the modified scaffold of the psammaplin A natural product obtained replacing the o-bromophenol unit by an indole ring. A series of indole-psammaplin A constructs were generated in a short synthetic sequence that attachs the oximinoamide chain to the corresponding C3 indole position. ...
Longo Stefania - - 2012
Intrauterine Growth Retardation (IUGR) is defined as a rate of growth of a fetus that is less than normal for the growth potential of the fetus (for that particular gestational age). Small for Gestational Age (SGA) is defined infant born following IUGR, with a weight at birth below the 10th ...
Keeve P L - - 2012
BACKGROUND AND OBJECTIVE: Stem cells derived from periodontal and palatal tissues may be useful for regenerative therapies of periodontal tissues. In addition to the use of single periodontium-derived stem cells (pdSCs) and palatal-derived stem cells (paldSCs), the application of pdSC and paldSC dentospheres, providing a pool of vital stem cells, ...
Liaugaudas G - - 2012
The decay time of luminescence from neutral nitrogen-vacancy (NV (0)) centres in synthetic diamond is reported. The intrinsic luminescence lifetime of NV (0) is measured as τ(r) = 19 ± 2 ns. Neutral substitutional nitrogen atoms [Formula: see text] are shown to quench luminescence from NV(0) by dipole-dipole resonant energy transfer at a rate such ...
Sanjaya Stephen - - 2012
A Cu-catalyzed aminoacetoxylation of N-alkenylamidines has been achieved using PhI(OAc)(2) as an oxygen source for synthesis of 4-acetoxymethyl-4,5-dihydroimidazoles, which could be further converted into 2,3-diaminopropanol derivatives using AlH(3) as a reductant.
Zhang K H L - - 2012
The growth of Bi on Ag(111) induces different surface structures, including [Formula: see text] surface alloy, Bi-[Formula: see text] overlayer and Bi(110) thin film, as a function of increasing Bi coverage. Here we report the study of electronic states of these structures using core level and valence band photoemission spectroscopy ...
Sargent M Catherine - - 2012
Orthopaedic residents and attending physicians who report having a supportive spouse show lower levels of burnout and psychological distress than those without supportive spouses. However, little is known about the experiences of the spouses. This nationwide study examines burnout, psychological distress, and marital satisfaction of the spouses and significant others ...
Flores-Gaspar Areli - - 2012
The first Pd-catalyzed intramolecular acylation of aryl chlorides via C-H bond functionalization is presented. The method allows for the synthesis of a variety of elusive benzocyclobutenones with a wide range of functional groups and substitution patterns. We demonstrate that a change in the ligand backbone dictates the selectivity pattern.
Dayeh Shadi Ahmad - - 2012
The growth of heteroepitaxially-strained semiconductors at the nanoscale enables tailoring of material properties for improved device performance. For core/shell nanowires (NWs), theoretical predictions of the coherency limits and the implications they carry remain uncertain without proper identification of the mechanisms by which strains relax. We present here for the Ge/Si ...
Capriles Vanessa D - - 2012
The effect of adding increasing levels of prebiotic inulin-type fructans (ITFs) (0, 4, 8, 10 and 12%) on the sensory and nutritional quality of gluten-free bread (GFB) was assessed. ITFs can provide structure and gas retention during baking, thus improving GFB quality by yielding better specific volume, softer crumb, improved ...
Cowdrey Felicity A - - 2012
Functional brain imaging studies have shown abnormal neural activity in individuals recovered from anorexia nervosa (AN) during both cognitive and emotional task paradigms. It has been suggested that this abnormal activity which persists into recovery might underpin the neurobiology of the disorder and constitute a neural biomarker for AN. However, ...
Karra Nour - - 2012
Pulmonary delivery of drug-loaded nanoparticles is a novel approach for lung cancer treatment and the conjugation of nanoparticles to a targeting ligand further promotes specificity of the carrier cargo to cancer cells. Notably, the epithelial cell adhesion molecule (EpCAM, CD326) is over expressed in lung cancer. Here, we report the ...
Nakano Hiroshi - - 2012
Columnaris disease, enteric septicemia of catfish, and streptococcosis are common bacterial diseases of certain freshwater fish and are caused by Flavobacterium columnare, Edwardsiella ictaluri, and Streptococcus iniae, respectively. During the process of evaluating several species of plants in order to isolate and identify compounds with toxicity against these bacteria, a ...
Shibuya Taizo - - 2012
The polaronic nature of excess electrons accompanying an oxygen vacancy in a TiO(2)(110) surface has been studied by several theoretical approaches. According to previous studies, DFT + U and hybrid functional methods predict different sites of localization of the polarons. In this paper, we conducted a thorough comparison of the results obtained ...
van der Woude L H V - - 2012
Background: With today's specialized medical care, life expectancy of persons with a spinal cord injury (SCI) has considerably improved. With increasing age and time since injury, many individuals with SCI, however, show a serious inactive lifestyle, associated with deconditioning and secondary health conditions (SHCs) (e.g. pressure sores, urinary and respiratory ...
Riaz Asif - - 2012
We report the controlled diffusion of gas-phase high-reactivity chemical species into long polymeric microcavities to form glass-like, low-permeability barrier films on the interior surfaces of the microcavities. Reactive species created from fragmentation of O(2) and hexamethyldisiloxane (HMDSO) in a radio-frequency (RF) plasma environment are allowed to diffuse into the microcavities ...
Milej Daniel - - 2012
It was reported that time-resolved reflectance measurements carried out during inflow and washout of an optical contrast agent may provide information on the blood supply to the brain cortex of human adults. It was also shown that a measurement of fluorescence excited in the dye circulating in the brain is ...
Aullón Gabriel - - 2012
To date, crystal structures of the cyclic mercury complexes [μ-1,2-(C(2)B(10)H(10))(n)Hg(n)], with n = {3, 4}, have been found. However, the same structures substituting Hg by Au, which implies a charge z = {-3, -4} for n = {3, 4} respectively, have not been found. In this work, we present geometrical ...
Husemoen L L N - - 2012
BACKGROUND/OBJECTIVES:Mild to moderate vitamin D insufficiency has been proposed as a risk factor for several common chronic diseases including type 2 diabetes. This study aimed to examine the association between serum 25-hydroxy vitamin D (25(OH)D) and incident diabetes.SUBJECTS/METHODS:The MONICA10 cohort consists of 2656 participants (men and women aged 41-71 years) ...
Turygin Nicole - - 2012
Objective: To determine the effect of the changing fifth edition of the Diagnostic and Statistical Manual (DSM-5) criteria on the developmental profiles of children diagnosed with an Autism spectrum disorder (ASD). Methods: This study examines the effect of DSM-5 changes on impairment profiles of a population of 2054 at-risk toddlers ...
Perdew John P - - 2012
Fullerene molecules such as C(60) are large nearly spherical shells of carbon atoms. Pairs of such molecules have a strong long-range van der Waals attraction that can produce scattering or binding into molecular crystals. A simplified classical-electrodynamics model for a fullerene is a spherical metal shell, with uniform electron density ...
Winkels Diny G M - - 2012
Objective: Commercially available virtual reality systems can possibly support rehabilitation objectives in training upper arm function in children with Cerebral Palsy (CP). The present study explored the effect of the Nintendo Wii™ training on upper extremity function in children with CP. Methods: During six weeks, all children received twice a ...
Murphy Elizabeth Carmel - - 2012
Among the Gram-positive anaerobic bacteria associated with clinical infections, the Gram-positive anaerobic cocci (GPAC) are the most prominent and account for approximately 25-30% of all isolated anaerobic bacteria from clinical specimens. Still, routine culture and identification of these slowly growing anaerobes to the species level has been limited in the ...
Morin Jean-Paul - - 2012
1. We review the specific approaches for lung tissue slices preparation and incubation systems and the research application fields in which lung slices proved to be a very efficient alternative to animal experimentation for biomechanical, physiological, pharmacological and toxicological approaches. 2. Focus is made on air-liquid interface dynamic organ culture systems that ...
Deshmukh-Taskar Priya - - 2012
OBJECTIVE: To examine the association between breakfast skipping and type of breakfast consumed with overweight/obesity, abdominal obesity, other cardiometabolic risk factors and the metabolic syndrome (MetS). DESIGN: Cross-sectional. Three breakfast groups were identified, breakfast skippers (BS), ready-to-eat-cereal (RTEC) consumers and other breakfast (OB) consumers, using a 24 h dietary recall. ...
Capo-Chichi José-Mario - - 2012
Mutations in the gene encoding the iron-sulfur-containing DNA helicase DDX11 (ChlR1) were recently identified as a cause of a new recessive cohesinopathy Warsaw breakage syndrome (WABS), in a single patient with severe microcephaly, pre- and postnatal growth retardation, and abnormal skin pigmentation. Here, using homozygosity mapping in a Lebanese consanguineous ...
Azulai Daniel - - 2012
Gold /silver nanowires of controlled diameter were synthesized from catalytic metal seed particles at the substrate/solution interface. Small seed nanoparticles of three different sizes: ~1 nm (11 gold atoms), ~1.4 nm (~55 gold atoms), and homemade nanoparticles of ~2 nm were used. By varying a single type of seed particle ...
Caciuc Vasile - - 2012
We have performed a systematic semi-empirical and ab initio van der Waals study to investigate the bonding mechanism of benzene (C(6)H(6)), triazine (C(3)N(3)H(3)) and borazine (B(3)N(3)H(6)) adsorbed on graphene and a single boron nitride (BN) sheet. The two semi-empirical approaches used to include the van der Waals (vdW) interactions in ...
Lynch Danielle C - - 2012
Acrodysostosis is characterized by nasal hypoplasia, peripheral dysostosis, variable short stature, and intellectual impairment. Recently, mutations in PRKAR1A were reported in patients with acrodysostosis and hormone resistance. Subsequently, mutations in a phosphodiesterase gene (PDE4D) were identified in seven sporadic cases. We sequenced PDE4D in seven acrodysostosis patients from five families. ...
Jacquet P - - 2012
Results obtained from the end of the 1950s suggested that ionizing radiation could induce foetal malformations in some mouse strains when administered during early pre-implantation stages. Starting in 1989, data obtained in Germany also showed that radiation exposure during that period could lead to a genomic instability in the surviving ...
Searle Julia - - 2012
Context: Acute myocardial infarction (AMI) related to percutaneous coronary intervention (PCI) (MI type 4a) occurs in up to 26% of elective patients. Objective: To evaluate if sFLT-1 helps to predict MI type 4a in troponin negative patients with elective PCI. Materials and methods: We enrolled 135 patients, 106 had a ...
Gerber Hans-Dieter - - 2012
To thoroughly study the functional role of prokaryotic t-RNA-guanine-transglycosylases which are essential in the pathogenesis of shigellosis, novel efficient, high-yielding synthetic approaches for preQ(1) base, Q base, as well as for (ent)-Q base mainly employing cheap and readily available starting materials have been developed. Q base as well as (ent)-Q ...
Olsson Sara K - - 2012
Olsson SK, Sellgren C, Engberg G, Landén M, Erhardt S. Cerebrospinal fluid kynurenic acid is associated with manic and psychotic features in patients with bipolar I disorder. Bipolar Disord 2012: 00: 000-000. © 2012 The Authors. Journal compilation © 2012 John Wiley & Sons A/S. Objectives:  Kynurenic acid (KYNA), an ...
Ghani E - - 2012
Spermatozoa are capable of producing small amounts of reactive oxygen species (ROS), and sperm in teratozoospermia generate more ROS than sperm in normozoospermia. The source of ROS production in ejaculated human sperm has not been fully clarified. Recently, NADPH oxidase 5 (NOX5) was detected in human sperm, and ROS generation ...
Wu Shing-Sheng - - 2012
Vitis thunbergii var. taiwaniana (VTT) is an indigenous Taiwanese wild grape and is used as a folk medicine in Taiwan. VTT is rich in polyphenols, especially quercetin and resveratrol derivatives, which were demonstrated to exhibit inhibitory activities against carcinogenesis and prevent some neurodegenerative diseases. (-)-Vitisin B is one of the ...
Ishizuka Takumi - - 2012
Toward new biotechnology by genetic alphabet expansion, we developed an efficient site-specific labeling method for large RNA molecules. The combination of unnatural base pair transcription and post-transcriptional modification by click chemistry enables simple RNA labeling with a wide variety of functional groups at desired positions, in a one-pot reaction.
Fang Jingjing - - 2012
A metabolic profiling study was carried out on rapeseed (Brassica napus L.). Eleven glucosinolates were identified by high-performance liquid chromatography (HPLC) coupled with diode array detection (DAD) and mass spectrometry (MS). Additionally, 18 phenolic compounds were profiled from an ethanol extract of rapeseed. Beside two major phenols, sinapine and methyl ...
Mesch Gustavo S - - 2012
This paper examines the relationship between attention to the mass media and concern about becoming infected with H1N1 in two nationwide random samples interviewed during the flu epidemic of 2009. The first sample (N = 1004) was taken at the end of the first wave of the outbreak in the US and ...
Donaldson D S - - 2012
The B subunit of E. coli heat-labile enterotoxin (EtxB) protects against the development of T helper type 1 (Th1)-mediated autoimmune pathologies in mice. Protection was transferable with splenic CD4(+) T cells and was less effective following CD25 depletion; implying a T regulatory cell (Treg)-mediated process. We hypothesized that if this ...
Stam Mette K - - 2012
An MRI-linac system provides direct MRI feedback and with that the possibility of adapting radiation treatments to the actual tumour position. This paper addresses the use of fast 1D MRI, pencil-beam navigators, for this feedback. The accuracy of using navigators was determined on a moving phantom. The possibility of organ ...
Bangalore Sripal - - 2012
β-Blockers remain the standard of care after a myocardial infarction (MI). However, the benefit of β-blocker use in patients with coronary artery disease (CAD) but no history of MI, those with a remote history of MI, and those with only risk factors for CAD is unclear. To assess the association ...
Dumantepe Mert - - 2012
Abstract Objective: To evaluate the efficacy of endovenous laser ablation (EVLA) of incompetent perforating veins (IPVs) with 1470 nm laser with 400 μm radial fiber. Background data: EVLA for perforating veins can be performed with insignificant postprocedural morbidity. This allows treatment to be offered to elderly patients with comorbidities that would preclude ...
Lemaire Katleen - - 2012
After food consumption, insulin-secreting pancreatic β-cells detect increased glucose and incretin hormones, and respond by releasing insulin. Wolfram syndrome 1, a protein that mitigates endoplasmic reticulum (ER) stress, is now shown to regulate insulin synthesis and release - revealing a molecular point of convergence between the ER stress and insulin ...
Agostinho Moreira J - - 2012
In this work we investigate the magnetic field dependence of A(g) octahedra rotation (tilt) and B(2g) symmetric stretching modes frequencies at different temperatures. Our field-dependent Raman investigation at 10 K is interpreted by an ionic displacive nature of the magnetically-induced ferroelectric phase transition. The increasing frequency of the A(g) tilt mode ...
Nanni Umberto - - 2012
Biobanks provide stored material to basic, translational, and epidemiological research and this material should be transferred without institute-dependent intrinsic bias.
The ISBER Biospecimen Science Working Group has released a "Standard PREanalytical Code" (SPREC), which is a proposal for a standard coding of the preanalytical options that have been adopted in order ...
Smith Catherine M - - 2012
Purpose: The aim of this study was to investigate experiences of participating in a feasibility trial of a novel physiotherapy intervention (Blue Prescription). The trial was designed to increase participation in physical activity for people with multiple sclerosis living in the community. Methods: We individually interviewed 27 volunteers from two ...
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