Search Results
Results 551 - 600 of 3179
< 7 8 9 10 11 12 13 14 15 16 17 >
Martha Satyabadi - - 2012
A series of visible light responsive nanorods of InGaZn mixed oxide photocatalyst are designed by varying the concentration of In(NO(3))(3)via a solid state reaction method without the need for a surfactant or template. The photocatalysts are characterized by XRD, diffuse reflectance UV-vis spectra, TEM, BET surface area analysis, PL, and ...
Balagopal Padmini - - 2012
PurposeThe purpose of this study was to test the effectiveness of a 6-month community-based diabetes prevention and management program in rural Gujarat, India.MethodsA community-based participatory research method was used to plan and tailor the intervention by engaging trained community health workers as change agents to provide lifestyle education, serve as ...
Yue Lan - - 2012
Photochemical switches represent a powerful method for improving pharmacological therapies and controlling cellular physiology. Here we report the photoregulation of GABA(A) receptors (GABA(A)Rs) by a derivative of propofol (2,6-diisopropylphenol), a GABA(A)R allosteric modulator, which we have modified to contain photoisomerizable azobenzene. Using α(1)β(2)γ(2) GABA(A)Rs expressed in Xenopus laevis oocytes and ...
Ishida Akio - - 2012
Aims: Age-related change of ankle-brachial index (ABI) within the general population, especially <40 years, has not been determined in large population studies. We evaluated the value of the ABI by age- and sex-related differences in a screened cohort.Methods and results: The ABI was examined in 13,211 participants (aged 21-89 years) ...
Kontos Anthony P - - 2012
Mild traumatic brain injury (mTBI) has gained considerable notoriety during the past decade of conflict in Afghanistan and Iraq. However, the relationship between combat-related mTBI and residual mTBI symptoms, post-traumatic stress disorder (PTSD) symptoms, and neurocognitive deficits remains unclear. The purpose of the study was to compare residual mTBI and ...
Enkvist Erki - - 2012
Up-regulation of an acidophilic protein kinase, CK2, has been established in several types of cancer. This cognition has made CK2 an important target for drug development for cancer chemotherapy. The characterization of potential drug candidates, determination of the structure and clarification of the functions of CK2 could be facilitated by ...
Gloria Antonio - - 2012
The requirement of a multifunctional scaffold for tissue engineering capable to offer at the same time tunable structural properties and bioactive interface is still unpaired. Here we present three-dimensional biodegradable polymeric (PCL) scaffolds with controlled morphology, macro-, micro-, and nano-mechanical performances endowed with bioactive moieties (RGD peptides) at surface. Such ...
Friedenreich Christine Marthe - - 2012
Markers of insulin resistance such as the adiponectin:leptin ratio (A:L) and the homeostasis model assessment ratio (HOMA-IR) are associated with obesity and hyperinsulinemia, both established risk factors for endometrial cancer, and may therefore be informative regarding endometrial cancer risk. This study investigated the association between endometrial cancer risk and markers ...
Hu Lanhua - - 2012
Ferrate [Fe(VI); FeO42-] is an emerging oxidizing agent capable of controlling chemical and microbial water contaminants. Here, inactivation of MS2 coliphage by Fe(VI) was examined. The inactivation kinetics observed in individual batch experiments was well described by a Chick-Watson model with first-order dependences on disinfectant and infective phage concentrations. The ...
Karade Vikas - - 2012
ABSTRACT: BACKGROUND: In a standard total knee replacement, tibial component alignment is a key factor for the long term success of the surgery. The purpose of this study is to compare the accuracy of extramedullary and intramedullary tibial cutting guides used in indigenous and imported implants respectively, in positioning of ...
Chuang Victor Tuan Giam - - 2012
OBJECTIVE:To comprehensively review the literature regarding the efficacy, safety, and costs associated with the use of levoleucovorin in cancer treatment and to assess whether levoleucovorin would be a reasonable alternative to the use of racemic leucovorin.DATA SOURCES:A MEDLINE search was conducted for English-language human studies published between January 1980 and ...
Ng Tsz Kin - - 2012
Adult stem cells are critical for the healing process in regenerative medicine. However, cigarette smoking inhibits stem cell recruitment to tissues and delays the wound healing process. This study investigated the effect of nicotine, a major constituent in the cigarette smoke, on the regenerative potentials of human mesenchymal stem cells ...
Penberthy Lynne - - 2012
BACKGROUND: Clinical trials (CTs) are the mechanism by which research is translated into standards of care. Low recruitment among underserved and minority populations may result in inequity in access to the latest technology and treatments, compromise the generalizability, and lead to failure in identification of important positive or negative treatment ...
Leroi A M - - 2012
OBJECTIVES:The objective of this study was to show that although transcutaneous electrical tibial nerve stimulation (TENS) is being increasingly used to treat fecal incontinence (FI), its efficacy has never been proved using controlled trials.METHODS:In this randomized, double-blind, sham-controlled trial, 144 patients aged 30-82 years from nine centers were randomly assigned ...
Staffa Katharina - - 2012
Gene expression of specific brain biomarkers offers the possibility to shed light on the diffi-cult molecular pathways of traumatic brain injury (TBI) and may be useful to estimate the age of trauma. Gene expression rates of cerebellar injuries are not yet sufficiently established. In 12 cases of TBI including a ...
Scherbaum Charles A - - 2012
A concern about personality inventories in diagnostic and decision-making contexts is that individuals will fake. Although there is extensive research on faking, little research has focused on how perceptions of personality items change when individuals are faking or responding honestly. This research demonstrates how the delta parameter from the generalized ...
Benitez-Herreros Javier - - 2012
PURPOSE: To evaluate the effect of the cannula removal technique on postoperative vitreous incarceration using an experimental model of vitrectomized eye. METHODS: In a prospective, experimental, randomized and observer-masked study, 118 cadaveric pig eyes were vitrectomized through 23-gauge transconjunctival sclerotomies. Once vitrectomy was finished, one of the superior cannulas was ...
Liu Jiyang - - 2012
A new nanocomposite material for enzyme immobilization and subsequent direct electrochemistry and electrocatalysis was developed by using 1,2-dimyristoyl-sn-glycero-3-phospho-(1-rac-glycerol)-phospholipid-monolayer-membrane-modified graphene (DMPG-G). Microperoxidase-11 (MP11) was chosen as a model enzyme to investigate the composite system. Owing to the improved conductivity and biocompatible microenvironment, MP11 that was immobilized in the matrix of the ...
Comper Maria L C - - 2012
BACKGROUND: Most of the available instruments aimed to assess risk exposure associated with work-related musculoskeletal disorders were originally developed in English, which makes their use difficult in countries such as Brazil. OBJECTIVE: To test the clinimetric properties of the Quick Exposure Check (QEC) instrument previously adapted into Brazilian-Portuguese. METHOD: The ...
Crespo-Otero Rachel - - 2012
The photochemistry of N-methylformamide (MF) is elucidated by investigating its photodissociation products generated by UV irradiation (248 nm) in an argon matrix (10 K). We find that, starting from trans-MF, prolonged irradiation produces cis-MF, CH(3) NH(2) and CO fragments as major products. Another photoproduct is identified as methylformimidic acid (FIA). Nonadiabatic dynamics ...
Gao Hongwei - - 2012
Background: Enzymatical conversion of A or B RBCs into group O RBCs (ECORBCs) was achieved by using α-N-acetylgalactosaminidase and α-galactosidase, respectively. Now, we initiated AB to O-RBC conversion by using these two enzymes together. But α-N-acetylgalactosaminidase and α-galactosidase's preserving and their reaction buffer were quite different. The aim of this ...
Rose P C - - 2012
BACKGROUND: Treatment options for drug-resistant tuberculosis (DR-TB) are limited. Linezolid has been successfully used to treat DR-TB in adults, but there are few case reports of its use in children for TB. The reported rate of adverse events in adults is high.METHODS: We conducted a retrospective review of children with ...
Schmitt Christian M - - 2012
Background: A free gingival graft (FGG) is currently the gold standard for augmenting small areas of keratinized mucosa. The porcine collagen matrix (CM) represents an alternative to autologous tissue harvesting. This study aimed to compare the CM versus FGGs for augmenting keratinized peri-implant mucosa, based on clinical and histological evaluations. ...
Liu Feng - - 2012
Nanopatterning by molecular self-assembly has been a topic of intense research in pursuit of 'bottom-up' methods of generating structures for use in nanotechnology. The systems most widely studied have been two- and three-dimensional morphologies of block copolymers. However, T- and X-shaped polyphilic liquid crystals have recently been shown to have ...
Calamia Valentina - - 2012
ABSTRACT: INTRODUCTION: Chondroitin sulfate (CS) is a symptomatic slow-acting drug for osteoarthritis (OA) widely used in clinic. The aim of this work is to find proteins whose secretion from cartilage cells under proinflammatory stimuli (interleukin-1beta, IL1beta) is regulated by CS, employing a novel quantitative proteomic approach. METHODS: Human articular chondrocytes ...
Carvalho G - - 2012
The benefits of tight glucose control in critically ill and surgical patients remains a subject of debate. While some studies demonstrated a survival benefit associated with intensive insulin therapy, more recent studies have failed to demonstrate this correlation. On the contrary, the difficulty in achieving normoglycemia with the conventional insulin ...
Berkessel Albrecht - - 2012
The synthesis of six enantiopure alpha,alpha,alpha',alpha'-tetrakisperfluoroalkyl/aryl-2,2'-dimethyl-1-3-dioxolan-4,5-dimethanols (TEFDDOLs), by addition of perfluorinated organolithium reagents or Ruppert's reagent (TMS-CF3) to iso-propylidene tartaric dichloride, is reported. X-Ray crystal structures of the TEFDDOLs alone or in complexes with H-bond acceptors such as water or DABCO revealed that this new class of highly fluorinated chiral ...
Perkins Martinique - - 2012
Objectives Using a large, national sample, this study examined perceived caregiving strain and other caregiving factors in relation to all-cause mortality.Method The REasons for Geographic and Racial Differences in Stroke (REGARDS) study is a population-based cohort of men and women aged 45 years and older. Approximately 12% (n = 3,710) ...
Bansal D - - 2012
Background:Emerging evidence suggests that diabetes may increase the risk of cancers. However, available evidence on prostate cancer is conflicting. We therefore examined the association between Type 2 diabetes and risk of prostate cancer by conducting a detailed meta-analysis of all studies published regarding this subject.Methods:PubMed database and bibliographies of retrieved ...
Srinivas Dharavath - - 2012
The amino, azido, nitro, and nitrogen-rich azole substituted derivatives of 1H-benzotriazole have been synthesized for energetic material applications. The synthesized compounds were fully characterized by (1) H and (13) C NMR spectroscopy, IR, MS, and elemental analysis. 5-Chloro-4-nitro-1H-benzo[1,2,3]triazole (2) and 5-azido-4,6-dinitro-1H-benzo[1,2,3]triazole (7) crystallize in the Pca2(1) (orthorhombic) and P2(1) /c (monoclinic) ...
Bröker Michael - - 2012
Neisseria meningitidis is differentiated into 12 distinct serogroups, of which A, B, C, W-135, X, and Y are medically most important and represent an important health problem in different parts of the world. The epidemiology of N. meningitidis is unpredictable over time and across geographic regions. Recent epidemiological surveillance has ...
Lee Younghyurk - - 2012
Background: The brain levels of glutamate (Glu) and glutamine (Gln) are partially regulated through the Glu-Gln cycle. Astrocytes play a role in regulating the Glu-Gln cycle, and loss of astrocytes has been associated with depressive disorders. We hypothesized that levels of Glu and Gln would be affected by astrocyte loss ...
Maeng Michael - - 2012
ABSTRACT: BACKGROUND: We evaluated the effectiveness and safety of a zotarolimus-eluting (ZES) versus a sirolimus-eluting (SES) coronary stent in a large cohort of patients treated with one of these stents in Western Denmark. METHODS: A total of 6,122 patients treated with ZES (n = 2,282) or SES (n = 3,840) ...
Hakim Iman A - - 2012
BACKGROUND: Several studies suggested that women may be more susceptible to oxidative damage induced by cigarette smoking, but the role of smoking status and antioxidant capacity in gender difference in susceptibility to oxidative damage has not been well studied. METHODS: We performed a cross-sectional analysis of the baseline data from ...
Reich Sabrina - - 2012
The crystal structure of the "ene" nicotinamide-dependent cyclohexenone reductase (NCR) from Zymomonas mobilis (PDB ID: 4A3U) has been determined in complex with acetate ion, FMN, and nicotinamide, to a resolution of 1.95 Å. To study the activity and enantioselectivity of this enzyme in the bioreduction of activated α,β-unsaturated alkenes, the ...
Tran Bich - - 2012
OBJECTIVES:Ecological studies have suggested an inverse relationship between latitude and risks of some cancers. However, associations between solar ultraviolet radiation (UVR) exposure and esophageal cancer risk have not been fully explored. We therefore investigated the association between nevi, freckles, and measures of ambient UVR over the life-course with risks of ...
Bluekens Adriana M J - - 2012
Purpose:To compare screen-film mammography with digital mammography in a breast cancer screening program, with a focus on the clinical relevance of detected cancers.Materials and Methods:The study was approved by the regional medical ethics review board. Informed consent was not required. Before the nationwide transition to digital mammography in the Dutch ...
Cortese Juliann - - 2012
Abstract As the United States prepares for the 2012 Presidential Election, we reflect on how the 2008 candidates and the voting public adopted social computing technology with specific focus on YouTube. Using the Social Influence Model as a framework, this article sought to examine how candidates adopted YouTube to determine ...
Hempel Klaus - - 2012
Approximately 3-20% of all reticulocytes in blood of healthy persons are immature and transferrin receptor positive (Tf-Ret). Tf-Ret were measured by flow cytometry in 27 patients treated with three different radiopharmaceuticals labeled with (131)I and in 25 healthy controls. Patients were chronically exposed within 6 days to blood doses from ...
Kaye Stan B - - 2012
Abstract PURPOSE: Hedgehog (Hh) pathway inhibition has been suggested as a potential maintenance treatment approach in ovarian cancer through disruption of tumor-stromal interactions. Vismodegib is an orally available Hh pathway inhibitor with clinical activity in advanced basal cell carcinoma and medulloblastoma. This phase II, randomized, double-blind, placebo-controlled trial was designed ...
Williams Hywel D - - 2012
The LFCS Consortium was established to develop standardized in vitro tests for lipid-based formulations (LBF) and to examine the utility of these tests to probe the fundamental mechanisms that underlie LBF performance. In this publication, the impact of bile salt (sodium taurodeoxycholate, NaTDC) concentration and LBF drug loading on the ...
Liu Ketang - - 2012
A functionalized periodic mesoporous organosilica with incorporated chiral bis(cyclohexyldiamine)-based Ni(II) complexes within the silica framework was developed by the co-condensation of (1R,2R)-cyclohexyldiamine-derived silane and ethylene-bridge silane, followed by the complexation of NiBr(2) in the presence of (1R,2R)-N,N'-dibenzylcyclohexyldiamine. Structural characterization by XRD, nitrogen sorption, and TEM disclosed its orderly mesostructure, and ...
Kocabay Ozge - - 2012
A novel highly sensitive electrochemical carboxymethylcellulose-gelatin-superoxide dismutase biosensor was used for the determination of superoxide radicals enhancement in tomato plants exposed to salinity, drought, cold and heavy metal stress. The variations in superoxide radicals depending on abiotic stress was determined using biosensor. The superoxide radical production with regard to control ...
Wencui Li - - 2012
To study the adhesion, proliferation and expression of bone marrow mesenchymal stem cells (BMSCs) on nano-hydroxyapatite (Nano-HA) bone graft material after transfection of adenovirus-mediated human bone morphogenetic protein-2 expression vector (Ad-BMP-2). BMSCs were transfected using Ad-BMP-2. Immunohistochemistry and Western blot were used to detect BMP-2 expression in transfected cells. After ...
Balasubramanian Gokulakrishnan - - 2012
OBJECTIVES:Chronic gastroesophageal reflux disease (GERD) is a risk factor for Barrett's esophagus (BE), the most important surrogate marker for the development of esophageal adenocarcinoma (EAC). The need to document the presence of intestinal metaplasia in esophageal biopsies from a columnar lined esophagus (CLE) to diagnose BE is debated. The objective ...
Xu Jianqiang - - 2012
BACKGROUND: ALTHOUGH CARINA SHIFT AND PLAQUE SHIFT ARE SUGGESTED AS MECHANISMS OF SIDE BRANCH OSTIAL (SBO) COMPROMISE AFTER MAIN VESSEL (MV) STENTING IN BIFURCATION LESIONS, THERE ARE FEW DIRECT EVIDENCE. OUR PURPOSE WAS TO CONFIRM THE MECHANISM OF SBO COMPROMISE AFTER MV STENT IMPLANTATION.METHODS AND RESULTS: INTRAVASCULAR ULTRASOUND IMAGES OF ...
Ohno-Matsui Kyoko - - 2012
Purpose. To examine the intrascleral and retrobular blood vessels in highly myopic eyes by swept-source optical coherence tomography (swept-source OCT). Methods. Six hundred and sixty-two eyes of 357 patients with pathologic myopia were studied. Radial scans along 12 meridians of 12 mm scan length centered on the fovea were made. ...
Kvavilashvili Lia - - 2012
Research on ageing and prospective memory-remembering to do something in the future-has resulted in paradoxical findings, whereby older adults are often impaired in the laboratory but perform significantly better than younger adults in naturalistic settings. Nevertheless, there are very few studies that have examined prospective memory both in and outside ...
Anonsen Jan Haug - - 2012
The bacterial human pathogen Neisseria gonorrhoeae expresses a general O-linked protein glycosylation system (Pgl) known to target at least 12 membrane-associated proteins. To facilitate a better understanding of the mechanisms, significance and function of this glycosylation system, we sought to further delineate the target proteome of the Pgl system. To ...
Leker Ronen R - - 2012
BACKGROUND AND PURPOSE: Our goal was to compare outcomes of patients with proximal middle cerebral artery occlusions treated with intravenous tissue plasminogen activator (tPA) with those of patients treated with stent-based thrombectomy (SBT). METHODS: Patients with proximal middle cerebral artery occlusions included in our prospective stroke registry were identified. Patients ...
< 7 8 9 10 11 12 13 14 15 16 17 >