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Results 351 - 400 of 3887
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Teixeira M C B - - 2012
Gastrointestinal (GI) complications are common after renal transplantation, mainly owing to immunosuppressive therapy. Assessment of GI transit time can facilitate rational management of these disorders. We evaluate the GI transit parameters in renal transplant recipients taking tacrolimus, azathioprine, and prednisone with the use of the alternate current biosusceptometry (ACB) technique ...
Ozçakar Z Birsin - - 2012
OBJECTIVE: Genetic and environmental factors have been implicated in disease severity and development of amyloidosis in familial Mediterranean fever (FMF). We investigated similarities in clinical characteristics, disease severity, and treatment response within siblings with FMF. METHODS: The study group consisted of 2 or more siblings who were followed in our ...
Glaser Stephanie S Department of Biochemistry, University of Cambridge, Cambridge, CB2 1GA, - - 2012
Most plastids proteins are post-translationally imported into organelles through multisubunit translocons. The TIC and TOC complexes perform this role in the two membranes of the plant chloroplast and in the inner two membranes of the apicoplasts of the apicomplexan parasites, Toxoplasma gondii and Plasmodium falciparum. Tic22 is a ubiquitous intermembrane ...
Davies Michelle - - 2012
The current study investigated the impact that respondent gender, victim-perpetrator relationship, and the level of emotional closeness had on attributions in a hypothetical child sexual abuse case. A total of 160 university students read a hypothetical scenario depicting a female child sexually abused by an adult male. The perpetrator was ...
Fladischer Stefanie - - 2012
This study shows that the morphology of organic/metal interfaces strongly depends on process parameters and the involved materials. The interface between organic n-type blocking layer materials and the top Ag cathode within an organic photodiode was investigated. Ag was deposited on either amorphous tris-8-hydroxyquinolinato-aluminium (Alq3) or crystalline 4,7-diphenyl-1,10-phenanthroline (Bphen) using ...
Rigamonti Antonello E - - 2012
Human growth hormone (hGH) is a heterogeneous protein hormone consisting of several isoforms. This heterogeneity is the consequence of multiple hGH genes, mRNA splicing, post-translational modifications and peripheral metabolism, and it represents one important reason for the disparity among GH assay results from different laboratories. However, other factors are involved: ...
Sokolenko Stanislav - - 2012
As native virus particles typically cannot be resolved using a flow cytometer, the general practice is to use fluorescent dyes to label the particles. In this work, an attempt was made to use a common commercial flow cytometer to characterize a phage display strategy that allows for controlled levels of ...
Zimmerman Ryan M - - 2012
The distal radioulnar joint (DRUJ) is a complex structure that contributes to full, painless forearm rotation and weight bearing. Stability requires adequate bony architecture and robust soft-tissue support. Arthritis of the DRUJ between the sigmoid notch of the distal radius and the ulnar head can be caused by traumatic, inflammatory, ...
Matsuo Takashi - - 2012
Porphycene is a structural isomer of porphyrin with 18pi-conjugated aromatic character. Porphycene modified with trifluoromethyl CF3 groups in the periphery of the framework readily affords the isolable 20pi-conjugated anti-aromatic form through a reaction with a proton-donating reductant. The 20pi-conjugated form can be characterized by not only a variety of spectroscopies ...
Ma Menglin - - 2012
Clostridium perfringens type C strains are the only non-type-A isolates that cause human disease. They are responsible for enteritis necroticans, which was termed Darmbrand when occurring in post-World War II Germany. Darmbrand strains were initially classified as type F because of their exceptional heat resistance but later identified as type ...
Miller Bryan Lee - - 2012
Researchers commonly use a person's perception of the drug use of friends to determine the impact that peers exert on one's own behavior. Recently, there has been concern over this measure's validity. Novel drugs, which are either newly discovered drugs or existing substances only recently used for recreational purposes, may ...
Ueba Tetsuya - - 2012
Background Indocyanine green videography has been introduced into neurosurgical fields for minimally invasive neurosurgery. To establish a new intraoperative imaging modality, we performed transdural indocyanine green videography during the surgery of meningiomas.Method  A dose of 12.5 mg of indocyanine green was injected transvenously in two cases of meningiomas just before the dural ...
Keel Pamela K PK Department of Psychology, Florida State University, Tallahassee, FL 32306, USA. - - 2013
Research supports both concurrent and prospective associations between peer behaviors and disordered eating levels in late adolescent and young adult men and women. However, no study has examined peer influence after a follow-up duration over which peer groups change dramatically. This study examined how college roommates' dieting predicted disordered eating ...
Filppula Anne M - - 2012
Recent data suggest that the role of CYP3A4 in imatinib metabolism is smaller than presumed. This study aimed to evaluate the quantitative importance of different cytochrome P450 (P450) enzymes in imatinib pharmacokinetics. First, the metabolism of imatinib was investigated using recombinant P450 enzymes and human liver microsomes with P450 isoform-selective ...
Kisel Yael - - 2012
Species population genetics could be an important factor explaining variation in clade species richness. Here, we use newly generated amplified fragment length polymorphism (AFLP) data to test whether five pairs of sister clades of Costa Rican orchids that differ greatly in species richness also differ in average neutral genetic differentiation ...
Smee Donald F - - 2012
Compounds lacking oral activity may be delivered intranasally to treat influenza virus infections in mice. However, intranasal treatments greatly enhance the virulence of such virus infections. This can be partially compensated for by giving reduced virus challenge doses. These can be 100- to 1,000-fold lower than infections without such treatment ...
Antoun Ayman - - 2012
NKG2D (KLRK1) is an activating receptor on natural killer (NK) and T-cells and binds a diverse panel of polymorphic ligands encoded by the MIC and RAET1 gene families. We studied the clinical importance of retinoic acid early transcript-1 (RAET1) polymorphism in allogeneic stem cell transplantation (SCT) by determining the frequency ...
Lapierre Matthew A - - 2012
OBJECTIVE:US parents were surveyed to determine the amount of background television that their children are exposed to as well as to isolate demographic factors associated with increased exposure to background television. After this, we ask how certain home media practices are linked to children's background television exposure.METHODS:US parents/caregivers (N = ...
de Savigny Don - - 2012
There are striking similarities in health system and other contexts between Tanzania and Ghana that are relevant to the scaling up of continuous delivery of insecticide treated nets (ITNs) for malaria prevention. However, specific contextual factors of relevance to ITN delivery have led implementation down very different pathways in the ...
Kaiser Meghann L - - 2012
Clearance of cervical spine (CS) precautions in the neurologically altered blunt trauma patient can be difficult. Physical examination is not reliable, and although computed tomography (CT) may reveal no evidence of fracture, it is generally believed to be an inferior modality for assessing ligamentous and cord injuries. However, magnetic resonance ...
Hu Wei-Shau WS Viral Recombination Section, HIV Drug Resistance Program, National Cancer Institute, Frederick, Maryland 21702-1201, - - 2012
Reverse transcription and integration are the defining features of the Retroviridae; the common name "retrovirus" derives from the fact that these viruses use a virally encoded enzyme, reverse transcriptase (RT), to convert their RNA genomes into DNA. Reverse transcription is an essential step in retroviral replication. This article presents an ...
Lee Sang Bae - - 2012
B23/nucleophosmin is a multifunctional protein that participates in cell survival signaling by shuttling between the nucleolus/nucleoplasm and nucleus/cytoplasm. In this paper, we report a novel neuroprotective function of B23 through regulation of the SIAH1-glyceraldehyde-3-phosphate dehydrogenase (GAPDH) death cascade. B23 physiologically bound to both SIAH1 and GAPDH, disrupting the SIAH1-GAPDH complex ...
Koivukangas Vesa - - 2012
Stenting has proven to be a promising treatment of spontaneous esophageal perforation, but currently, the scientific background to treatment of this condition is limited. Fourteen consecutive patients with spontaneous esophageal perforation were treated with coated self-expandable stent and a debridement procedure (three patients by thoracotomy, four by thoracoscopy, three by ...
Scott Ian A - - 2012
Published research evidence does not automatically diffuse into clinical practice but requires active processes of translation that start with clinicians' awareness of the science and end with patient adherence to the recommended care. Many barriers thwart the uptake of valid and clinically important research into practice, with cognitive, motivational and ...
Ricaud S - - 2012
A mode-locked thin-disk laser based on Yb:CALGO is demonstrated for the first time. At an average output power of 28 W we obtained pulses with a duration of 300 fs and a pulse energy of 1.3 μJ. 197 fs pulses with 0.9 μJ of energy were achieved at an average output power of 20 W. The ...
Danz Norbert - - 2012
The position of light-emitting molecules can be identified using interferometric approaches. Standard schemes utilize constructive interference to obtain a sectioned area of interest with high detection efficiency. The examination of organic light-emitting diodes (OLED) removes the common constraint of low light levels and enables a more generalized analysis. The OLED ...
Mai Kenny T - - 2012
Postoperative flexion is an important factor in the outcome of total knee arthroplasty. Although normal activities of daily living require a minimum of 105° to 110° of flexion, patients from non-Western cultures often engage in activities such as kneeling and squatting that require higher flexion. The desire to achieve greater ...
Machado S - - 2012
The scarcity of organs available for transplantation has led to the use of kidneys from old deceased donors including those ≥70 years of age. The results of kidney transplants performed using such "limit" organs warrent further study. We retrospectively evaluated all cadaveric heart-beating renal transplants performed from September 1996 to ...
Oliveira-Braga K A - - 2012
All transplant patients are at increased risk of developing pulmonary infections, a significant cause of morbidity and mortality. Immunosuppressants increase the incidence of lung infection by acting not only directly on the inflammatory cells, but also on the native immune system. Experimental studies have shown corticosteroid therapy, which is used ...
Alkhawajah Mona M - - 2012
Multiple sclerosis (MS) is a demyelinating disorder of the central nervous system (CNS) but the causes have not been defined. The disease process appears to involve interplay between environmental factors and certain susceptibility genes. It is likely that the identification of the exact etiological mechanisms will permit the development of ...
Wieneke Heinrich - - 2012
AIMS: Leadless pacing can be done by transmitting energy by an alternating magnetic field from a subcutaneous transmitter unit (TU) to an endocardial receiver unit (RU). Safety and energy consumption are key issues that determine the clinical feasibility of this new technique. The aims of the study were (i) to ...
Wang Hong H Mouse Biology Unit, European Molecular Biology Laboratory (EMBL), Via Ramarini 32, 00015 Monterotondo, - - 2013
The capacity to sense temperature is essential for the survival of all animals. At the molecular level, ion channels belonging to the transient receptor potential (TRP) family of channels function as temperature sensors in animals across several phyla. TRP channels are opened directly by changes in temperature and show pronounced ...
Singer Susanne - - 2012
The aim of this study was to determine the effect of art therapy on post-traumatic growth in patients with haematological malignancies in a non-randomised trial (n = 36, intervention group; n = 129, control group). Art therapy was administered over a period of 22 weeks in small groups. Post-traumatic growth ...
Yeap Swee Pin - - 2012
A detailed study on the conflicting role of colloid stability plays in magnetophoresis is presented. Magnetic iron oxide particles (MIOPs) which were sterically stabilized via surface modificaiton with poly(sodium 4-styrene sulfonate) of different molecular weight (ie. 70 kDa and 1000 kDa) were employed as our model system. Both sedimentation kinetics ...
Li Xiaoyan - - 2012
p53-binding protein-1 (53BP1) plays a critical role in cell cycle checkpoint and DNA repair activities. Recently, 53BP1 was recognized as a potential tumor suppressor gene. In this report, we investigated its tumor suppressor function in breast cancer. In clinical samples, we observed a lower level of 53BP1 expression in the ...
Löfkvist Ulrika - - 2012
Löfkvist, U., Almkvist, O., Lyxell, B. & Tallberg, I.-M. (2012). Word fluency performance and strategies in children with cochlear implants: age-dependent effects? Scandinavian Journal of Psychology. Word fluency was examined in 73 Swedish children aged 6-9 years divided into two age groups, 6-7 and 8-9 years; 34 deaf children with cochlear implants ...
Wilkins John T - - 2012
Background: It is unclear if associations between a parental history of premature CVD (pCVD) and subclinical atherosclerosis are attenuated by adjustment for long-term risk factor levels through middle adulthood.Design: Prospective community-based cohort study.Methods: CARDIA participants who attended the year-20 exam (n = 2283, mean age 45 years) were grouped by ...
Baumgarten A - - 2012
New diagnostic tools and therapeutic options for Non Hodgkin Lymphoma (NHL) contributed to several improvements in the understanding and treatment of this hematological malignancies. In diffuse large cell lymphoma (DLBCL) gene expression profiling and molecular analyses of myc and bcl-2 gene rearrangements resulted in the description of new DLBCL entities ...
Sigmarsdóttir Margrét - - 2012
Sigmarsdóttir, M. and Björnsdóttir, A., (2012). Community implementation of PMTO™: Impacts on referrals to specialist services and schools. Scandinavian Journal of Psychology. In 2000, the city of Hafnarfjörður, Iceland, implemented Parent Management Training - Oregon Model (PMTO(™) ) to prevent and treat behavioral problems among children. This paper describes the ...
Lakshmipriya Nagarajan - - 2012
There is little data on the type of vegetable oil used and the prevalence of metabolic syndrome (MS) in Asian Indians. Food frequency questionnaire was used to document the type of cooking oil in 1875 adults in Chennai city. MS was assessed by new harmonizing criteria. The prevalence of MS ...
Nomura Mitsushiro - - 2012
Reaction of tropolone or hinokitiol with phosphorus pentasulfide (P(2)S(5)) directly gives the sulfurized precursor [PS(2)(SST)](2) or [PS(2)(SSH)](2) (SST = dithiotropolonato or SSH = dithiohinokitiolato). The resulting [PS(2)(SST)](2) or [PS(2)(SSH)](2) is further reacted with [CpCoI(2)(CO)] (Cp = η(5)-cyclopentadienyl) to form the organometallic [CpCo(I)(SST)] (1) or [CpCo(I)(SSH)] (2), respectively. 1 and 2 ...
Tryon Valerie L - - 2012
Many different species of animals including mole rats, pigeons, and sea turtles are thought to use the magnetic field of the earth for navigational guidance. While laboratory rats are commonly used for navigational research, and brain networks have been described in these animals that presumably mediate accurate spatial navigation, little ...
Tiziana Arcangeli - - 2012
Abstract OBJECTIVES: to reassess the usefulness of midtrimester uterine Doppler in low risk multiparous women. METHODS: we prospectively recruited low risk pregnant women at 20-22 weeks attending our clinic. Among those, women with a favourable obstetric history (group A) were distinguished from nulliparous (group B) and of each group we ...
Pedersen Cort A CA Department of Psychiatry, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599-7160, USA. - - 2013
The neuropeptide, oxytocin (OT), has been reported to block tolerance formation to alcohol and decrease withdrawal symptoms in alcohol-dependent rodents. Numerous recent studies in human subjects indicate that OT administered by the intranasal route penetrates into and exerts effects within the brain. In a randomized, double-blind clinical trial, intranasal OT ...
Dreher Lena - - 2012
The increasing use of mesenchymal stromal cells (MSC) in clinical cellular therapy requires a safe and controlled production process compliant with Good Manufacturing Practice (GMP). Pooled blood group AB human serum (HS) has been used to replace fetal bovine serum (FBS), critically rated by the regulatory agencies, since it can ...
Hyde Rebecca - - 2012
OBJECTIVES:To determine whether maternal report of infant behavioral dysregulation at 6 months is associated with a higher prevalence of behavioral concerns at 5, 14, and 21 years of age; and to assess the extent to which maternal and social factors may affect reported child behavior outcomes.METHODS:From the Mater-University of Queensland ...
Sciascia S - - 2012
Objectives: To evaluate the clinical accuracy of antiphospholipid antibody (aPL) specificities both, individually and/or in combination, in a wide cohort of systemic lupus erythematosus (SLE) patients in an attempt to identify a panel of tests that may provide the best accuracy for diagnosing antiphospholipid syndrome (APS). Patients and Methods: This ...
Bertino E - - 2012
Objective: To discuss the duration and types of breastfeeding and to identify the factors associated with the early introduction of formula milk. Materials and methods: This longitudinal study was conducted in the largest birthing centre of Turin. 562 mother-infant pairs were selected randomly and enrolled from among all the births ...
Finigan Ryan - - 2012
The objective of this study was to determine if elderly trauma patients are at risk for contrast-induced nephropathy (CIN). A retrospective study was conducted identifying 362 patients 65 years and older in our Level I trauma center who received computerized tomography (CT) scans with intravenous contrast. CIN was defined as ...
Oliaei Sepehr - - 2012
Recent advances in optical technologies have produced laser systems capable of optimizing the appearance of scars from various etiologies. Laser treatment can commence as early as the time of the initial injury and as late as several years after the injury. Optimal results can now be attained with minimal down ...
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