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Dong Charlotte X - - 2012
Dysregulation of nutrient homeostasis is implicated in the current epidemics of obesity and type 2 diabetes mellitus. The maintenance of homeostasis in the setting of repeated cycles of feeding and fasting occurs through complex interactions between metabolic, hormonal and neural factors. Although pancreatic islets, the liver, muscle, adipocytes and the ...
Han Young Ah - - 2012
Ginger has long been used worldwide as a spice, seasoning, and wine and is also used as a traditional medicine. There have been no previous studies of the potential beneficial effects of the ginger constituent 12-dehydrogingerdione (12-DHGD). We investigated the anti-inflammatory effect of 12-DHGD on lipopolysaccharide (LPS)-stimulated Raw 264.7 cells. ...
Dang Dong-Bin - - 2012
A 2D Wells-Dawson-based silver(i) coordination polymer was achieved based on silver-Schiff base building blocks and [P(2)Mo(18)O(62)](6-) clusters using AgNO(3), N,N'-bis(furan-2-ylmethylene)hydrazine and Keggin [PMo(12)O(40)](3-) as original materials at room temperature. It is structurally characterized by IR spectroscopy, (31)P NMR, XRPD, thermogravimetric (TG) analyses and X-ray crystallography. The structure of exhibits a ...
Chen Xiao - - 2012
The complete mitogenomes of the endangered Asian giant softshell turtle Pelochelys cantorii (Testudinata: Trionychidae) were first determined from two living specimens, with the lengths of 17,612 and 17,499 bp, which showed the typical mitogenomic characteristics of vertebrates. An A+1 frameshift mutation at position 174 of the ND3 gene was identified. Seven ...
Meng Xueping - - 2012
The mitochondrial genome sequence of Coelomactra antiquata (Mollusca: Bivalvia) in Zhangzhou (zz-mtDNA) was fully sequenced and compared with that in Rizhao (rz-mtDNA) in this study. A tRNA (tRNA(Met)) located between tRNA(Ala) and cox1 genes was identified in zz-mtDNA but not in rz-mtDNA. The largest non-coding region (NCR; MNR) contained 11 ...
Stoklosa Jakub - - 2012
In capture-recapture models, survival and capture probabilities can be modelled as functions of time-varying covariates, such as temperature or rainfall. The Cormack-Jolly-Seber (CJS) model allows for flexible modelling of these covariates; however, the functional relationship may not be linear. We extend the CJS model by semi-parametrically modelling capture and survival ...
Müller Knut - - 2012
This article deals with the measurement of strain in semiconductor heterostructures from convergent beam electron diffraction patterns. In particular, three different algorithms in the field of (circular) pattern recognition are presented that are able to detect diffracted disc positions accurately, from which the strain in growth direction is calculated. Although ...
Varga Elisabeth - - 2012
Beer is one of the most popular beverages worldwide. Malted cereal grains are among the basic ingredients and hence mycotoxin contamination might occur. Previous studies reported the presence of the Fusarium mycotoxins deoxynivalenol (DON) and 3-acetyl-deoxynivalenol (3ADON), as well as of the masked mycotoxin deoxynivalenol-3-glucoside (D3G) in beer. In the ...
Butler Matt - - 2012
Adenosine possesses potent anti-inflammatory properties which are partly mediated by G(i) -coupled adenosine A3 receptors (A3Rs). A3R agonists have shown clinical benefit in a number of inflammatory conditions although some studies in A3R-deficient mice suggest a pro-inflammatory role. We hypothesized that, in addition to cell signaling effects, A3R compounds might ...
Scalco Nayara - - 2012
OBJECTIVE: The present study investigated Guarani village interviewees' diet changes over time, their perceptions about the changes and the effects of these changes on their health. DESIGN: The study employed qualitative methods with a sample of Guarani Indians selected by snowball sampling. Ethnographic methods and techniques included field diaries, informal ...
Chevalier Y - - 2012
Background and Objectives  Total knee replacement (TKR) is the treatment of choice in case of end-stage knee arthropathy, the main complication of haemophilia. We report here a retrospective evaluation of 72 total knee replacement in 51 haemophilia A and B patients using continuous infusion of factor concentrates (CIFC). Materials and ...
Oh Dae-Ju - - 2012
The taxonomic relationship between two Korean field mice species, Apodemus agrarius coreae and A. a. chejuensis, as well as their possible historic migration routes, was examined by molecular genetic analysis of the complete mitochondrial cytochrome b gene of 73 mice collected from the Korean Peninsula and Jeju Island. Our findings ...
Pietrzak Robert H - - 2012
OBJECTIVE: Alprazolam is a benzodiazepine that, when administered acutely, results in impairments in several aspects of cognition, including attention, learning, and memory. However, the profile (i.e., component processes) that underlie alprazolam-related decrements in visual paired associate learning has not been fully explored. METHODS: In this double-blind, placebo-controlled, randomized cross-over study ...
van Beers Miranda M C - - 2012
Adverse immune responses severely hamper the success of biopharmaceutical therapies. Possible clinical consequences include anaphylaxis, reduced drug half-life and neutralization of the therapeutic protein as well as the endogenous human homologue. Controlling potential triggers of the immune system helps to minimize the immunogenicity of biopharmaceuticals, a crucial consideration in biopharmaceutical ...
Shibata Maho - - 2012
Recent studies of prostate cancer and other tumor types have revealed significant support, as well as unexpected complexities, for the application of concepts from normal stem cell biology to cancer. In particular, the cell of origin and cancer stem cell models have been proposed to explain the heterogeneity of tumors ...
Nolte Kim - - 2012
Abstract The aim of this study was to evaluate the benefits and limitations of using three dimensional (3D) musculoskeletal modelling (LifeModeler(TM)) in assessing the safety and efficacy of exercising on an abdominal crunch resistance training machine. Three anthropometric cases were studied, representing a 5(th) percentile female, and 50(th) percentile and ...
de Bruin Eveline A - - 2012
OBJECTIVE: We investigated the association between mean corpuscular volume (MCV), carbohydrate-deficient transferrin (CDT), and gamma-glutamyl transferase (GGT) levels and gray and white brain matter in male drinkers to find out which if any of these biomarkers of alcohol consumption is indicative for alcohol-related differences in brain volume. METHOD: Plasma levels ...
Iannucci Glen J - - 2012
OBJECTIVE: Necrotising enterocolitis is a rare, though catastrophic complication that may occur in term newborns with congenital heart disease. There is considerable controversy regarding the factors that lead to necrotising enterocolitis in this population. We sought to determine the incidence of necrotising enterocolitis among term and near-term newborns with congenital ...
Brown Kate L - - 2012
OBJECTIVE: To categorise records according to primary cardiac diagnosis in the United Kingdom Central Cardiac Audit Database in order to add this information to a risk adjustment model for paediatric cardiac surgery. DESIGN: Codes from the International Paediatric Congenital Cardiac Code were mapped to recognisable primary cardiac diagnosis groupings, allocated ...
Sadowska-Woda Izabela - - 2012
Abstract It has been suggested lately that erythrocytes contribute significantly to the oxidant scavenging capacity (OSC) of blood and that surface adsorption of polyphenols enhances the antioxidant capacity of erythrocytes. The aim of this study was to examine the contribution of erythrocytes to the OSC of whole blood measured with ...
Yang Xin-An - - 2012
A simple and green flow injection chemiluminescence (FI-CL) method for determination of the fungicide azoxystrobin was described for the first time. CL signal was generated when azoxystrobin was injected into a mixed stream of luminol and KMnO(4) . The CL signal of azoxystrobin could be greatly improved when an off-line ...
Schoormans Dounya - - 2012
BACKGROUND: Patient satisfaction with care has received little attention within the field of congenital heart disease. Our objective was to examine patient satisfaction with the care received when undergoing open-heart surgery in order to identify the best and worst aspects of peri-operative care. Moreover, we examined whether having contact with ...
Liu Li-Ting - - 2012
Objective: The purpose of this study is to examine the psychometric properties of the Chinese version of the Paediatric Volitional Questionnaire (PVQ-C) for use amongst preschoolers in Taiwan. Methods: Forty preschoolers with developmental delays were randomly selected from northern Taiwan, along with another 40 typically developing preschoolers. The data was ...
Audemard A - - 2012
Microsporidiosis is an opportunistic infection in organ transplant recipients and patients with other cellular immunodeficiency. Fumagillin is an effective treatment against Enterocytozoon bieneusi, one of the two main species causing the microsporidiosis involved in human diseases. We report the first case, to our knowledge, of a probable drug-induced aseptic meningoencephalitis, ...
Jo Seong-Gi - - 2012
Guide me: Laser confocal microscope photoluminescence (LCM-PL) and optical waveguiding characteristics for tin(IV) porphyrin based microcrystalline rods and plates were investigated. The efficiency of optical waveguiding for the rods (0.04 μm(-1) ) was five times better than for the plate, due to stronger π-π interaction and a short layer distance (3.035 ...
Travia Nicholas E - - 2012
The thorium(iv) tetraiodide complex ThI(4)(DME)(2) () (DME = 1,2-dimethoxyethane) has been prepared in high yield by reacting the corresponding chloride complex ThCl(4)(DME)(2) with an excess of trimethylsilyl iodide (Me(3)SiI) in toluene. This new route avoids the use of thorium metal as a reagent. ThI(4)(DME)(2) () exhibits excellent thermal stability compared ...
Iannucci Glen J - - 2012
The combination of both right and left heart obstruction has only rarely been described in the medical literature. We present three cases of coarctation of the aorta in patients with variants of tetralogy of Fallot and hypothesise that this condition may be more common than previously suspected and could represent ...
Petchsang Nattasamon - - 2012
The electrostatic alignment and directed assembly of semiconductor nanowires into macroscopic, centimeter-long yarns is demonstrated. Different morphologies can be produced, including longitudinally segmented/graded yarns or mixed composition fibers. Nanowire yarns display long range photoconductivities and open up exciting opportunities for potential use in future nanowire-based textiles or in solar photovoltaics.
Boukhris Maher - - 2012
Pelargonium graveolens (Geraniaceae) was characterized with respect to its chemical composition, antioxidant potential and antimicrobial activities. This is the first investigation focusing on the comparison of both essential oil and polar extracts from this species. The chemical composition of the essential oil of the aerial parts of P. graveolens was ...
Lhuillier Emmanuel - - 2012
HgTe colloidal quantum dots (CQD) in an inorganic As(2) S(3) matrix allow 100-fold higher mobility with optimized transport properties compared to HgTe-organic CQD film while remaining intrinsic. The material's electronic properties are measured by field effect transistors as a function of temperature and the responsivity and detectivity of the mid-IR ...
Lam Walter Y H - - 2012
OBJECTIVE: To compare "survival" and "success" of implant-supported crowns (ISC) and tooth-supported 2-unit cantilevered resin-bonded bridges (cRBB) in the rehabilitation of a bounded single tooth space (BSTS), after an observation period of ≥5 years. METHODS: A case-control study among subjects who received ISC or cRBB rehabilitation at a teaching hospital. The ...
Marasca Roberto - - 2012
Deletion on the long arm of chromosome 11 occurs in 5-20% of chronic lymphocytic leukaemia (CLL) patients. We analysed clinical-biological characteristics of 131 CLL patients carrying 11q deletion documented before therapy (de novo 11q deleted CLL). De novo 11q deleted CLL were characterized by high frequencies of unmutated immunoglobulin variable ...
Xiang Yu-Tao - - 2012
OBJECTIVE: Bipolar disorder (BD) is frequently misdiagnosed as major depressive disorder (MDD), which may lead to inappropriate treatment and poor outcomes. This study aimed to examine prescribing patterns of antidepressants, antipsychotics and mood stabilizers in BD patients misdiagnosed with MDD in China. METHODS: A total of 1487 patients originally diagnosed ...
Burr Jamie F - - 2012
Abstract Mountain biking is a popular recreational pursuit and the physiological demands of cross-country style riding have been well documented. However, little is known regarding the growing discipline of gravity-assisted downhill cycling. We characterised the physiological demands of downhill mountain biking under typical riding conditions. Riding oxygen consumption ([Vdot]O(2)) and ...
Bao Ying - - 2012
Flexible and freestanding poly(methyl methacrylate) nanofibers containing the upconversion nanoparticles (UCNPs) of lanthanide-doped sodium yttrium fluoride have been successfully fabricated via an electrospinning process. The UCNPs in nanofibers commonly formed chain-like aggregates aligned along the fiber axes. The effect of the electrospinning process on the upconversion properties of the embedded ...
Sakamaki Kazuhiro - - 2012
FADD is an adaptor protein that transmits apoptotic signals from death receptors. Additionally, FADD has been shown to play a role in various functions including cell proliferation. However, the physiological role of FADD during embryonic development remains to be delineated. Here, we show the novel roles FADD plays in development ...
Tyner Sophie E - - 2012
World Youth Day 2008 was held in Sydney, Australia in July 2008. New South Wales (NSW) Health, the government health provider in Australia's most populous state, worked with partner agencies to provide medical services via on-site medical units at key event venues. A post-event review of medical records from the ...
Li Qilu - - 2012
This study presents the first investigation of concentrations and congener group patterns of atmospheric short-chain chlorinated paraffins (SCCPs) throughout East Asia. Based on an absorption rate calibration experiment, a spatial survey of SCCPs was performed using passive air samplers in China, Japan and South Korea during two separate periods in ...
Qian Qin - - 2012
Direct selective determination of cysteine in the cerebral system is of great importance because of the crucial roles of cysteine in physiological and pathological processes. In this study, we report a sensitive and selective colorimetric assay for cysteine in the rat brain with gold nanoparticles (Au-NPs) as the signal readout. ...
Gumennik Alexander - - 2012
A new all-in-fiber trace-level chemical sensing approach is demonstrated. Photoconductive structures, embedded directly into the fiber cladding along its entire length, capture light emitted anywhere within the fiber's hollow core and transform it directly into an electrical signal. Localized signal transduction circumvents problems associated with conventional fiber-optics, including limited signal ...
Toma Luminita Marilena - - 2012
We herein present the synthesis and magneto-structural study of a new family of heterobimetallic chains of general formula {[Fe(III)(dmbpy)(CN)(4)](2)M(II)(H(2)O)(2)}(n)·pnH(2)O [dmbpy = 4,4'-dimethyl-2,2'-bipyridine; M = Mn (), Cu (), Ni () and Co () with p = 4 (), 3 (), 9 () and 3.5 ()] which were prepared by using ...
Chen Tianyou - - 2012
Organic-inorganic hybrid mesoporous polymers were successfully synthesized by using a template-directed free radical polymerization technique in aqueous solution at 0-5 oC with oxidative complexes as self-decomposed soft templates. The oxidative complexes ((CTA)2S2O8), which were formed between anionic oxidant (S2O82-) and cationic surfactant (cetyl trimethylammonium bromide, CTAB) at 0-5 oC, can ...
Franklin Robin J M - - 2012
Multiple sclerosis (MS) is an inflammatory demyelinating disease that is considered by many people to have an autoimmune aetiology. In recent years, new data emerging from histopathology, imaging and other studies have expanded our understanding of the disease and may change the way in which it is treated. Conceptual shifts ...
Zhao Jiaji - - 2012
An efficient synthesis of 2- or 4-iododibenzofurans through CuI-mediated sequential iodination/cycloetherification of two aromatic C-H bonds in o-arylphenols has been developed. Both the preexisting electron-withdrawing groups (NO(2), CN, and CHO) and the newly introduced iodide are readily modified for a focused dibenzofuran library synthesis. Mechanistic studies and DFT calculations suggest ...
Shi Yizhi - - 2012
Amplitude modulation (AM) scanning force microscopy (SFM) is superior to frequency modulation SFM in simplicity, sensitivity, and stability, but is still replaced by the latter because it is too slow when the Q factor is high (bandwidth < 0.5 Hz for Q > 50,000 and resonant frequency ω0 < 50 ...
Cao Zhen-Hui - - 2012
Pu-erh tea has shown anti-obesity effects but little is known about its effect on proliferation and differentiation of preadipocytes. This study investigated the effects of the aqueous extracts of raw pu-erh tea and ripened pu-erh tea on proliferation and differentiation of murine 3T3-L1 preadiopocytes. We examined dose and time effects ...
Pan Zhi-Zhen - - 2012
4'-Thiosemicarbazonegriseofulvin, a new thiosemicarbazide derivative of griseofulvin, was synthesized and evaluated for its potential on the control of enzymatic browning and postharvest disease of fruits. Browning on fruits is mainly due to the enzymatic oxidation of phenolic compounds catalyzed by tyrosinase. 4'-thiosemicarbazonegriseofulvin could effectively inhibit the activity of tyrosinase and ...
Martínez-Aguilar Juan - - 2012
This review documents the uses of quantitative mass spectrometry applied to colorectal cancer (CRC) proteomics for biomarker discovery and molecular pathway profiling. Investigators are adopting various labeling and label-free mass spectrometry approaches to quantitate differential protein levels in cells, tumours and plasma/serum. We comprehensively review recent uses of this technology ...
Boschetti Elisa - - 2012
In this study, we sought the use of cultured human abdominal aortic aneurysm (AAA) tissue to investigate the transcriptional effects of some bioactives, whose role in the prevention of atherosclerotic plaque development through the regulation of gene expression has been hypothesized. After supplementation with n - 3 polyunsaturated fatty acids or epigallocatechin-3-gallate, ...
Karimi Mohsen - - 2012
We report a case of tricuspid atresia with transposed great arteries and rudimentary right ventricle owing to which the patient developed severe subaortic stenosis and restrictive bulboventricular foramen 5 years after her extracardiac Fontan operation. She underwent a successful modified Damus-Kaye-Stansel operation using her native pulmonary valve. Spiral cardiac computed ...
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