Search Results
Results 101 - 150 of 3883
1 2 3 4 5 6 7 8 9 10 >
Gerin M - - 2012
The Herschel-guaranteed time key programme PRobing InterStellar Molecules with Absorption line Studies (PRISMAS)(1) is providing a survey of the interstellar hydrides containing the elements C, O, N, F and Cl. As the building blocks of interstellar molecules, hydrides provide key information on their formation pathways. They can also be used ...
Kragh Helge - - 2012
Triatomic hydrogen became a major research area only after 1980, but its history goes back to J. J. Thomson's discovery in 1911. In fact, the possible existence of H(3) was suggested as early as 1895. This paper outlines the history of H(3) and H(3)(+) up to the mid-1930s, when chemists ...
Indriolo Nick - - 2012
Owing to its simple chemistry, H(3)(+) is widely regarded as the most reliable tracer of the cosmic-ray ionization rate in diffuse interstellar clouds. At present, H(3)(+) observations have been made in over 50 sight lines that probe the diffuse interstellar medium (ISM) throughout the Galaxy. This small survey presents the ...
Johnsen Rainer - - 2012
Recombination in plasmas containing H(3)(+) ions occurs not only by binary recombination but also by third-body-assisted mechanisms, the principal subject of this contribution. Third-body effects on recombination are of interest for model calculations of hydrogen discharges, their spectral emissions and the inference of binary recombination coefficients from plasma afterglow data.
Polyansky Oleg L - - 2012
The molecular ion H(3)(+) is the simplest polyatomic and poly-electronic molecular system, and its spectrum constitutes an important benchmark for which precise answers can be obtained ab initio from the equations of quantum mechanics. Significant progress in the computation of the ro-vibrational spectrum of H(3)(+) is discussed. A new, global ...
Adamowicz Ludwik - - 2012
The most accurate electronic structure calculations are performed using wave function expansions in terms of basis functions explicitly dependent on the inter-electron distances. In our recent work, we use such basis functions to calculate a highly accurate potential energy surface (PES) for the H(3)(+) ion. The functions are explicitly correlated ...
Aragon Katherine - - 2012
In the last 6 months of life, many older adults will experience a hospitalization, followed by a transfer to a skilled nursing facility (SNF) for additional care. We sought to examine patterns of Medicare posthospitalization SNF use in the last 6 months of life. We used data from the Health ...
Higuchi Masayoshi M Centre for Eye Research Australia, East Melbourne, Victoria, - - 2013
Both reactive oxygen species (ROS) and Forkhead box O (FOXO) family transcription factors are involved in the regulation of adipogenic differentiation of preadipocytes and stem cells. While FOXO has a pivotal role in maintaining cellular redox homeostasis, the interactions between ROS and FOXO during adipogenesis are not clear. Here we ...
Rifkind Joseph M - - 2013
The physiological mechanism(s) for recognition and removal of red blood cells (RBCs) from circulation after 120 days of its lifespan is not fully understood. Many of the processes thought to be associated with the removal of RBCs involve oxidative stress. We have focused on hemoglobin (Hb) redox reactions, which is ...
Zhu Heng H Department of Pharmacology and Molecular Sciences, The Johns Hopkins University School of Medicine, MD, USA. - - 2012
Functional protein microarrays were developed as a high-throughput tool to overcome the limitations of DNA microarrays and to provide a versatile platform for protein functional analyses. Recent years have witnessed tremendous growth in the use of protein microarrays, particularly functional protein microarrays, to address important questions in the field of ...
Zito Ester - - 2013
Peroxiredoxin 4 (PRDX4) is an endoplasmic reticulum (ER)-resident peroxiredoxin that has the characteristic of coupling hydrogen peroxide (H(2)O(2)) catabolism with oxidative protein folding. This enzymatic arrangement involves the ingenious use of H(2)O(2) as a substrate to streamline protein metabolism. Mice with compound mutations in Prdx4 and Ero1 have revealed the ...
Barbagallo Ignazio - - 2013
Many physiological effects of natural antioxidants, their extracts or their major active components, have been reported in recent decades. Most of these compounds are characterized by a phenolic structure, similar to that of α-tocopherol, and present antioxidant properties that have been demonstrated both in vitro and in vivo. Polyphenols may ...
Cho Seung-Hyun - - 2013
The cell envelope of aerobic bacteria is an oxidizing environment in which most cysteine residues are involved in disulfide bonds. However, reducing redox pathways are also present in this cellular compartment where they provide electrons to a variety of cellular processes. The membrane protein DsbD plays a central role in ...
Polo Andrea - - 2012
The study characterized the sessile microbial communities on mortar and stone in Milan University's Richini's Courtyard and investigated the relationship between airborne and surface-associated microbial communities. Active colonization was found in three locations: green and black patinas were present on mortar and black spots on stone. Confocal laser scanning microscopy, ...
Seibyl John - - 2012
Brain imaging of striatal dopamine terminal degeneration serves an important role in the clinical management of Parkinson's disease (PD). Imaging biomarkers for interrogating dopaminergic systems are used for clarifying diagnosis when only subtle motor symptoms are present. However, motor dysfunction is not the earliest symptom of PD. There is increasing ...
Otao R - - 2012
Bile acid signalling and farnesoid X receptor activation are assumed to be essential for liver regeneration. This study was designed to investigate the association between serum bile acid levels and extent of liver regeneration after major hepatectomy. Patients who underwent left- or right-sided hemihepatectomy between 2006 and 2009 at the ...
Krook Melanie A - - 2012
Polyphenols found in foods and beverages are under intense scrutiny for their potential beneficial effects on human health. We examined the stability of two bioactive polyphenols, epigallocatechin-O-gallate (EGCg) and 1,2,3,4,6-penta-O-galloyl-β-D-glucopyranose (PGG), in a model digestive system at low oxygen tension with and without added digestive components and foods. Both compounds ...
Yamazaki S - - 2012
Abdominal drains have been placed prophylactically and removed in liver resection without robust evidence. The present study was designed to establish the optimal time for removal of such drains. Data on abdominal prophylactic drains were analysed in a consecutive series of patients who underwent liver resection for malignancy between 2006 ...
Chen Shu-Wen - - 2012
To examine demographic characteristics, knowledge, and attitudes of adolescents on osteoprotective practices in Taichung City, Taiwan. Using convenience sampling, 329 students from randomly selected high schools and colleges were recruited to respond to a 58-item questionnaire. Adolescents had significantly higher overall osteoprotective behavior practice scores than those of young adults ...
Hong Oisaeng - - 2012
To determine stages of hearing-protection behavioral change and their relationships with cognitions and hearing status. A cross-sectional study of 769 construction workers who completed a survey and audiometric tests. The majority of participants (over 64%) were in the preparation stage. Participants in the action/maintenance stage demonstrated significantly greater benefits, self-efficacy, ...
Kim M J - - 2012
The purpose of this study was to identify management strategies for non-functioning pancreatic neuroendocrine tumours (NF-PNETs) by analysis of surgical outcomes at a single institution. Archived records of patients with NF-PNETs who underwent surgery between 1994 and 2010 were reviewed. Among 125 patients, the median tumour size was 2·5 (range ...
Wickrama Thulitha - - 2012
To test a longitudinal and multilevel model predicting young adult risky sexual behaviors and sexually transmitted infections. Data from 14,058 participants in 3 waves were used to link community and family disadvantage, adolescent adjustment problems, and risky sexual behaviors with STIs. Community-level disadvantage, being African American, and being female remained ...
Stocks Janet - - 2012
Lung disease begins early in life in cystic fibrosis (CF), yet our understanding of CF lung abnormalities in the first years of life remains limited. By facilitating earlier diagnosis, newborn screening for CF provides the opportunity to understand and characterize presymptomatic lung disease in infants and young children. This could ...
Park J Y - - 2012
There is a lack of reports evaluating the outcomes of robotic gastrectomy and conventional laparoscopic surgery. The aim of this study was to compare the surgical stress response and costs of robot-assisted distal gastrectomy (RADG) with those of laparoscopy-assisted distal gastrectomy (LADG). This prospective study compared a cohort of patients ...
Habr-Gama A - - 2012
The Editors welcome topical correspondence from readers relating to articles published in the Journal. Responses should be sent electronically via the BJS website (http://www.bjs.co.uk). All letters will be reviewed and, if approved, appear on the website. A selection of these will be edited and published in the Journal. Letters must ...
Tung Gregory J - - 2012
To examine the application of behavioral science theories to explain the voting behavior of legislators for public health policies. We conducted a systematic review to identify studies that examined factors associated with legislator support, intention to vote, or actual votes on public health policies, emphasizing those grounded in behavior science ...
Adams Marc A - - 2012
To explore among older adults whether multivariate neighborhood profiles were associated with physical activity (PA) and BMI. Adults (66-97 years) were recruited from Baltimore-Washington, DC (n=360), and Seattle-King County, Washington (n=368), regions. Latent profile analyses were conducted using the Neighborhood Environment Walkability Scale. ANCOVA models tested for criterion validity of ...
Burbach Guido J - - 2012
Cox-2 inhibitors have been identified as promising candidates for cancer therapy. Several studies have recently proposed the use of celecoxib in long-term low-intensity chemotherapy protocols for recurrent tumors. However, drug-induced hypersensitivity reactions may force discontinuation of the medication and, thus, significantly complicate successful care. Here, we report on celecoxib desensitization ...
Briez N - - 2012
Morbidity after oesophageal cancer surgery remains high, mainly due to major postoperative pulmonary complications (MPPCs). The aim of this study was to test the hypothesis that hybrid minimally invasive oesophagectomy (HMIO) decreases the 30-day MPPC rate without compromising oncological outcomes. Consecutive patients undergoing curative oesophagectomy for cancer by laparoscopic gastric ...
Li Kaigang - - 2012
To develop and test an explicative model of leisure-time physical activity (LTPA), including 6 selected contributory factors: self-efficacy, self-regulation, social support, perceived physical environment, outcome-expectancy value, and policy beliefs. A social-ecological model of LTPA using the structural equation modeling technique was estimated in a regional, church-going sample of 649 African ...
Cook-Craig Patricia - - 2012
To examine how individuals residing in low-income neighborhoods use their social networks for health advice. Secondary data analysis of 363 individuals living in low-income neighborhoods was conducted using social network analysis and logistic regression techniques. Findings suggest that residents typically seek health advice from one or 2 friends and family ...
Rocchiccioli Silvia - - 2012
Proteomics is considered a promising tool in the discovery of new biomarkers and/or therapeutic targets. The aim of this study was to identify proteins expressed in the plasma of survivors of myocardial infarction and possible correlations between expression of some proteins and the severity of coronary artery disease (CAD) in ...
Torosyan Nare - - 2012
Recently, the National Institute on Aging and the Alzheimer's Association identified specific structural and functional neuroimaging findings as valuable markers of biological processes occurring in the human brain, especially processes that herald impending dementia caused by Alzheimer's disease (AD) in its prodromal form. In particular, the imaging modalities of magnetic ...
Takahashi Masanori - - 2012
This prospective study was performed in 179 hepatocellular carcinoma (HCC) lesions treated by radio-frequency ablation (RFA) to explore the clinical outcome of "linear enhancement" on contrast-enhanced sonogram. Thirty-three lesions (18.4%) showed linear enhancement, a linear-shaped positive enhancement in the RFA-treated area. Seventeen of them were followed up with no treatment ...
Ward Rose Marie - - 2012
To establish a short measure of attitudes toward sexual consent in the context of alcohol consumption. Using a multistage and systematic measurement development process, the investigators developed the Alcohol and Sexual Consent Scale using a sample of college students. The resulting 12-item scale, the Alcohol and Sexual Consent Scale, was ...
Carl C - - 2012
Fouling-release (FR) coatings minimise the adhesion strength of fouling organisms. This study describes improved technologies to control the settlement and adhesion of the important fouling organism Mytilus galloprovincialis by incorporating the nanofillers titanium dioxide (TiO(2)) and carbon nanotubes (CNTs) in polydimethylsiloxane (PDMS) matrices. The incorporation of TiO(2) prevented larval settlement ...
Lewis David H - - 2012
Stroke and cerebrovascular diseases are major causes of mortality, morbidity, and disability. Nuclear Medicine, primarily via tomographic methods, has made significant contributions to the understanding of the hemodynamic and metabolic consequences of cerebrovascular diseases. In this review, the findings in acute, subacute, and chronic cerebrovascular diseases are described. Many of ...
Tamber Mandeep S - - 2012
Epilepsy is the most common serious brain disorder in children, occurring in all parts of the world and within every stratum of the population. Through its effects, it exerts a significant physical, psychological, economic, and social toll on children and their caregivers. Historically, the surgical treatment of epilepsy has been ...
Kung Justin W - - 2012
Digital professionalism is increasingly being integrated into postgraduate medical education. We developed a small-group, reflective practice-based session incorporating radiology-specific cases to heighten residents' awareness about digital professionalism. Case-based, radiology-specific scenarios were created for a small-group, reflective practice-based session on digital professionalism. Anonymous pre- and postsession surveys evaluating residents' use of ...
Francis W R - - 2012
Changes in human bone marrow associated with the systemic inflammatory response to injury are little understood. It was hypothesized that major trauma results in an altered bone marrow leucocyte progenitor profile, with either uniform depletion or the balance between multipotent and committed progenitors varying, depending on whether self-renewal is favoured ...
Stremitzer S - - 2012
The prognostic value of KRAS mutation in patients with colorectal cancer liver metastases (CLM) receiving neoadjuvant chemotherapy including bevacizumab before liver resection is unclear. The KRAS and BRAF status of resected CLM was assessed in prospectively studied patients. Mutations were correlated with recurrence-free and overall survival. Only patients with remaining ...
Kahraman Deniz - - 2012
The aim was to assess the value of tumor lesion glycolysis (TLG) and tumor lesion proliferation (TLP) determined by FDG and 3'-deoxy-3'-F-fluorothymidine (FLT) PET for response prediction and prognostic differentiation in patients with advanced non-small cell lung cancer (NSCLC) treated with erlotinib. FDG-PET and FLT-PET were performed in 30 patients ...
Leventhal Adam M - - 2012
To examine the relation of 2 measures of anhedonia-a specific facet of depression indicative of inability to experience pleasure-to physical activity (PA). Cross-sectional correlational survey study of 157 college students (73% female, M age 19.9 years). One or both measures of anhedonia were inversely associated with walking frequency, moderate-intensity PA ...
Kelly Kimberly M - - 2012
To examine perceptions of cervical cancer risk in elevated-risk Appalachians. Appalachian women (n=571) completed interviews examining self-regulation model factors relevant to perceived risk of cervical cancer. Women with good/very good knowledge of cervical cancer, greater worry, and history of sexually transmitted infection had higher odds of rating their perceived risk ...
Hock Barry D - - 2012
Human polymorphonuclear leucocytes (PMN) are thought to be immunosuppressive. The suppressive mechanism(s) used by PMN are, however, not well defined and in this study they were analysed using T-cell responses to CD3(+) CD28 monoclonal antibodies (mAb) as a readout. We demonstrate that in vitro activated PMN (PMN(act)) can, without any ...
Weigand Luise U - - 2012
Adoptive transfer of T cells genetically modified with tumour-specific T-cell receptors (TCR) is a promising novel approach in the treatment of cancer. We have previously isolated an allorestricted MHC class I-restricted TCR with specificity for Formin-like protein 1 (FMNL1) with potent activity against chronic lymphocytic leukaemia cells. CD4(+) T cells ...
Escoto Kamisha Hamilton - - 2012
To describe time-related beliefs and behaviors regarding healthful eating, indicators of dietary intake, and their associations with the number of weekly hours of paid work among young adults. Population-based study in a diverse cohort (N=2287). Working > 40 hours per week was associated with time-related barriers to healthful eating most ...
Daley Ellen M EM Department of Community and Family Health, University of South Florida, College of Public Health, Tampa, FL, USA. - - 2012
To report psychosocial differences between self-reported HPV-positive and HPV-negative Florida men. Men (n=536) in an HPV natural-history study completed a cross-sectional survey (2007-2010). Most participants were white, non-Hispanic, and unmarried with some college education. HPV knowledge was high overall. HPV-positive men reported more negative emotions and perceived threat (P<0.05). HPV-negative ...
Herholz Karl K School of Cancer and Enabling Sciences, The University of Manchester, Wolfson Molecular Imaging Centre, Manchester, England. - - 2012
This review addresses the specific contributions of nuclear medicine techniques, and especially positron emission tomography (PET), for diagnosis and management of brain tumors. (18)F-Fluorodeoxyglucose PET has particular strengths in predicting prognosis and differentiating cerebral lymphoma from nonmalignant lesions. Amino acid tracers including (11)C-methionine, (18)F-fluoroethyltyrosine, and (18)F-L-3,4-dihydroxyphenylalanine provide high sensitivity, which ...
Mayes Maureen D MD Division of Rheumatology and Clinical Immunogenetics, University of Texas Health Science Center, Houston, Texas 77030, USA. - - 2012
The last decade has seen enormous progress in understanding genetic associations of systemic sclerosis to explain the observed heritability. This review highlights the most recent findings and places them in the context of proposed functional roles. Over 30 genes and gene regions have now been identified as scleroderma susceptibility loci. ...
1 2 3 4 5 6 7 8 9 10 >