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Results 601 - 650 of 3887
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Lima M L - - 2012
There is a growing need to improve heart preservation benefit the performance of cardiac operations, decrease morbidity, and more important, increase the donor pool. Therefore, the objective of this study was to evaluate the cardioprotective effects of Krebs-Henseleit buffer (KHB), Bretschneider-HTK (HTK), St. Thomas No. 1 (STH-1), and Celsior (CEL) ...
Elgazwy Abdel-Sattar S Hamad - - 2012
Khelline is naturally occurring furochromone exhibited significant Epidermal Growth Factor Receptor (EGFR) inhibitory activity. The newly synthesized compounds 2-5 displayed the most potent EGFR inhibitory activity on MCF-7 and HeLa. In vitro study against 59 different human tumour cell lines derived from nine cancer type in NCI (USA), which was ...
Ghosh Deepa - - 2012
BACKGROUND: Small vitiliginous patches have been treated with epidermal grafts or their cell suspensions. In an attempt to overcome some of the shortcomings of cell suspension delivery, we have delivered melanocytes on a polymeric film. OBJECTIVES: To evaluate the clinical effectiveness of a cultured graft consisting of autologous cultured melanocytes ...
Bayindir Funda - - 2012
Introduction:  Understanding the distribution of incisal translucency will provide clinicians a guide to use this knowledge to improve the esthetic replication of anterior restorations. The aim of this study is to investigate the distribution of incisal translucency of unrestored vital natural maxillary central, lateral, and canine vital teeth from a ...
Kemp Catherine Jarrett CJ Department of Animal Science, University of California, Davis, California, USA. - - 2012
An attempted proteomic study of Daphnia pulex response to sodium chloride exposure revealed an unexpected result: very strong proteome degradation previously observed in D. pulex is halted when animals have been exposed to elevated salinity prior to protein extraction. Further characterization of conditions controlling proteome degradation shows that the proteolytic ...
Becker-Santos Daiana D DD Department of Integrative Oncology, British Columbia Cancer Research Centre, Vancouver, British Columbia, Canada V5Z - - 2012
Approximately half of prostate cancers (PCa) carry TMPRSS2-ERG translocations; however, the clinical impact of this genomic alteration remains enigmatic. Expression of v-ets erythroblastosis virus E26 oncogene like (avian) gene (ERG) promotes prostatic epithelial dysplasia in transgenic mice and acquisition of epithelial-to-mesenchymal transition (EMT) characteristics in human prostatic epithelial cells (PrECs). ...
Langer Marybeth - - 2012
The lung is the site of entry for Bacillus anthracis in inhalation anthrax, the deadliest form of the disease. Bacillus anthracis produces virulence toxins required for disease. Alveolar macrophages were considered the primary target of the Bacillus anthracis virulence factor lethal toxin because lethal toxin inhibits mouse macrophages through cleavage ...
Sha Qiong - - 2012
The diversity of Salmonella was analyzed in biofilm and water samples from the spring and slough arms of Spring Lake, the headwaters of the San Marcos River, Texas, during the drought of 2011, with only one potential run-off event at the beginning of the study. Salmonellae were detected in semi-selective ...
Liu Chong - - 2012
Gallium phosphide (GaP) nanowire photocathodes synthesized using a surfactant-free solution-liquid-solid (SLS) method were investigated for their photoelectrochemical evolution of hydrogen. Zinc as a p-type dopant was introduced into the nanowires during synthesis to optimize the photocathode's response. Investigation of the electrical properties of Zn-doped GaP nanowires confirmed their p-type conductivity. ...
Domingues Vera S - - 2012
To understand how organisms adapt to novel habitats, which involves both demographic and selective events, we require knowledge of the evolutionary history of populations and also selected alleles. There are still few cases in which the precise mutations (and hence, defined alleles) that contribute to adaptive change have been identified ...
Ward Roslyn - - 2012
This study evaluates kinematic movements of the jaw and lips in six children (3-11 years) with moderate-to-severe speech impairment associated with cerebral palsy before, during, and after participation in a motor-speech (PROMPT) intervention program. An ABCA single subject research design was implemented. Subsequent to the baseline phase (A), phase B ...
Grégoire Charles - - 2012
We report a case of severe daptomycin-induced immune thrombocytopenia in a patient treated for methicillin-resistant Staphylococcus epidermidis and ampicillin-resistant Enterococcus faecalis bacteremia acquired in an intensive care unit. Serum antibodies bound to platelets in the presence of daptomycin on flow cytometry. There was no evidence of other causes of thrombocytopenia. ...
Hindi Sajedah M - - 2012
Skeletal muscle is a postmitotic tissue that repairs and regenerates through activation of a population of stem-cell-like satellite cells. However, signaling mechanisms governing adult skeletal muscle regeneration remain less understood. In the present study, we have investigated the role of tumor necrosis factor (TNF) receptor-associated factor 6 (TRAF6), an adaptor ...
Salm F - - 2012
Chemotherapeutic drug resistance is one of the major causes for treatment failure in high-risk neuroblastoma (NB), the most common extra cranial solid tumor in children. Poor prognosis is typically associated with MYCN amplification. Here, we utilized a loss-of-function kinome-wide RNA interference screen to identify genes that cause cisplatin sensitization. We ...
Poncet Valérie V Institut de Recherche pour le Développement (IRD), Unité Mixte de Recherche-Diversité Adaptation et Développement des plantes (UMR DIADE), BP 64501, 34394 Montpellier Cedex 5, France. - - 2012
• Informative markers are required for assessing the diversity of Amborella trichopoda, the only species of its order, endemic to New Caledonia and considered to be the sister species to all flowering plants. Therefore, expressed sequence tag (EST)-based microsatellite markers were developed. • Fifty-five microsatellite loci were characterized in 14896 ...
Mahler Donald A - - 2012
Abstract Background: Patients who exhibit a suboptimal peak inspiratory flow rate (PIFR) against the resistance (resist) of a dry powder inhaler (DPI) may not be able to effectively inhale the medication into their lower respiratory tract. PIFRresist was measured using the In-Check DIAL(®) to simulate the resistance of the Diskus(®) ...
Carlson Daniel F - - 2012
Transcription activator-like effector nucleases (TALENs) are programmable nucleases that join FokI endonuclease with the modular DNA-binding domain of TALEs. Although zinc-finger nucleases enable a variety of genome modifications, their application to genetic engineering of livestock has been slowed by technical limitations of embryo-injection, culture of primary cells, and difficulty in ...
Lee Peter S - - 2012
Continual and rapid mutation of seasonal influenza viruses by antigenic drift necessitates the almost annual reformulation of flu vaccines, which may offer little protection if the match to the dominant circulating strain is poor. S139/1 is a cross-reactive antibody that neutralizes multiple HA strains and subtypes, including those from H1N1 ...
Nissen Nicholas N - - 2012
Pancreatic fistula (PF) continues to be the Achilles' heel of pancreaticoduodenectomy (PD) with both morbidity and mortality linked to its occurrence. The optimal drain management strategy after PD remains unclear. We evaluated drain amylase (DA) levels on postoperative Day (POD) 0 to 5 in 76 consecutive patients undergoing PD to ...
Rogers John - - 2012
To identify how to translate dental public health surveillance and broader research into policy and practice. Via a literature review to identify both the potential uses of surveillance data and key elements in the policy making process. Then through a consideration of Australian dental public health examples to identify ways ...
Gordon Leslie B - - 2012
Cell biologists love to think outside the box, pursuing many surprising twists and unexpected turns in their quest to unravel the mysteries of how cells work. But can cell biologists think outside the bench? We are certain that they can, and clearly some already do. To encourage more cell biologists ...
Rosendaal F R - - 2012
See also Lowe GDO. Epidemiology of venous thromboembolism: the need for large (including prospective) studies and meta-analyses. This issue, pp 2186-8 and El-Galaly TC, Kristensen SR, Overvad K, Steffensen R, Tjønneland A, Severinsen MT. Interaction between blood type, smoking and factor V Leiden mutation and risk of venous thromboembolism: a Danish ...
Chitgarha Mohammad Reza - - 2012
We experimentally demonstrate a tunable and reconfigurable optical discrete Fourier transform (DFT) to demultiplex orthogonal-frequency-division-multiplexed subcarriers with 2/3/4 subcarriers at 20/40  GHz frequency spacing. An average power penalty of ∼5  dB (∼3.5) at bit error ratio of 10<sup>-9</sup> is achieved for 4×20  Gbit/s (4×10  Gbit/s) OFDM signal with 20 GHz frequency spacing.
Chen Chih-Wei - - 2012
In this Letter, we present a three-dimensional (3D) imaging system with axially distributed sensing (ADS) using an electronically controlled liquid crystal (LC) lens. The proposed system performed an optical image acquisition by varying the focal lengths of the LC lens without mechanical movements of an image sensor. Multiple images with ...
Korovessis Panagiotis - - 2012
As a result of reading this article, physicians should be able to:1.Understand the importance of early diagnosis and treatment of spinal infection in an effort to avoid devastating and crippling complications such as paralysis, painful deformity, and death.2.Understand current perceptions in the ongoing debate of whether operative or conventional treatment ...
Dell Agnolo C M - - 2012
There has been a great improvement in transplantation medicine in Brazil in the last 2 decades. However, there remain several barriers regarding notification of brain and cardiac death as well as completion of the donation process. This retrospective study was performed between January 2008 and December 2010. We reviewed all ...
Fiorelli A I - - 2012
Endomyocardial biopsy (EMB) plays an important role in allograft surveillance to screen an acute rejection episode after heart transplantation (HT), to diagnose an unknown cause of cardiomyopathies (CMP) or to reveal a cardiac tumor. However, the procedure is not risk free. The main objective of this research was to describe ...
Turan Taylan - - 2012
ABSTRACT The objective of this study was to determine the changes in protein profiles of U-266 multiple myeloma cells in response to Bortezomib. Bortezomib inhibited cell proliferation and increased loss of mitochondrial membrane potential and caspase-3 activity in a dose dependent manner. DECODON Delta2D Version 4.3 software demonstrated 37 differentially ...
Taylor Matthew P MP Department of Molecular Biology, Princeton University, Princeton, NJ 08544, - - 2012
The spread of viral infection within a host can be restricted by bottlenecks that limit the size and diversity of the viral population. An essential process for alphaherpesvirus infection is spread from axons of peripheral nervous system neurons to cells in peripheral epithelia (anterograde-directed spread, ADS). ADS is necessary for ...
Drogoudi Pavlina D - - 2012
Almond protein and potassium (K), phosphorus (P), calcium (Ca) and magnesium (Mg) contents were determined in 72 cultivars and accessions grown in France, Greece and Italy, as part of the networking of European SAFENUT AGRI GEN RES project, which aimed to explore and valorize the almond genetic resources in Europe. ...
Pluess Michael - - 2012
The notion that some people are more vulnerable to adversity as a function of inherent risk characteristics is widely embraced in most fields of psychology. This is reflected in the popularity of the diathesis-stress framework, which has received a vast amount of empirical support over the years. Much less effort ...
O'Neill Patrick Ross - - 2012
We show that DNA hairpins template the site-specific assembly of fluorescent few-atom Ag clusters on DNA nanotubes. Fluorescent clusters form only at hairpin sites and not on the double stranded DNA scaffold, allowing for spatially programmed self-assembly. Ag clusters synthesized on hairpins protruding from DNA nanotubes can have nearly identical ...
Mutlu Asuman - - 2012
Platelet apoptosis and activation have been studied in human platelets treated with BH3-only mimetic ABT-737 and calcium ionophore A23187, agents triggering apoptosis through the intrinsic mitochondrial pathway. Platelet apoptosis was determined as activation of crucial apoptosis-associated caspases, initiator caspase-9 of intrinsic apoptosis pathway, executioner caspase-3 and initiator caspase-8 of extrinsic ...
Dani Carlo - - 2012
We aimed to assess the current knowledge on the nutritional management of preterm infants at risk of developing bronchopulmonary dysplasia (BPD) or with BPD. We considered the evidence supporting the actual fluid and energy intake, proteins, lipids, and electrolytes requirement, and need for other nutrients in preterm infant at risk ...
Lau Briana - - 2012
The current data available describing the relationship of obesity and abdominal wall hernias is sparse. The objective of this study was to investigate the current prevalence of noninguinal abdominal wall hernias and their correlation with body mass index (BMI) and other demographic risk factors. Patients with umbilical, incisional, ventral, epigastric, ...
Joo Chirlmin - - 2012
Single-molecule (sm) fluorescence detection is a powerful method for studying biological events without time and population averaging. Förster (fluorescence) resonance energy transfer (FRET) is a spectroscopic technique in which the efficiency of energy transfer from donor to acceptor molecules is used to determine distances between molecules in the 30-80 Å ...
Cheng Xiang - - 2012
T lymphocytes exhibit pro-inflammatory or anti-inflammatory activities in obesity and diabetes, depending on their subtypes. Guanidine-rich immunosuppressive oligodeoxynucleotides (ODNs) effectively control Th1/Th2-cell counterbalance. This study reveals a non-toxic regulatory ODN (ODNR01) that inhibits Th1- and Th17-cell polarization by binding to STAT1/3/4 and blocking their phosphorylation without affecting Th2 and regulatory ...
Jablonka Eric M - - 2012
Chemoimmobilization with botulinum toxin A is an ideal biochemical agent that allows near-total elimination of muscle pull on the healing facial wound. The goal of chemoimmobilization of facial cutaneous wounds is to eliminate dynamic tension on the healing tissues to improve wound healing and minimize scarring for optimal aesthetic results.
Fritz Deborah - - 2012
Constipation remains a challenging problem for patients and caregivers in home health. In Part 1 of this 2-part series, the scope, physiology, and evidence-based practice for nonpharmacological interventions for constipation are discussed. Part 2 will focus on pharmacological management of constipation, including medication cost, prevention of occurrence, and implications for ...
Soares Neelkamal S - - 2012
ABSTRACT:: Developmental-behavioral pediatrics (DBP) is recognized as one of the fields with the greatest shortages of pediatric subspecialists. Families who access care often must travel great distances to tertiary academic medical centers or endure long waiting lists. While the shortages are likely to persist due to limited provider availability and ...
Englert Chris - - 2012
In the present article, we analyzed the role of self-control strength and state anxiety in sports performance. We tested the hypothesis that self-control strength and state anxiety interact in predicting sports performance on the basis of two studies, each using a different sports task (Study 1: performance in a basketball ...
Rouifed Mohamed Said - - 2012
Room-temperature quantum-confined Stark effect in a Ge/SiGe quantum-well structure is reported at the wavelength of 1.3 μm. The operating wavelength is tuned by the use of strain engineering. Low-energy plasma-enhanced chemical vapor deposition is used to grow 20 periods of strain-compensated quantum wells (8 nm Ge well and 12 nm Si<sub>0.35</sub>Ge<sub>0.65</sub> barrier) on ...
Liu Kexin - - 2012
We demonstrate that one-way electromagnetic modes could be sustained by the edge of a gyromagnetic photonic crystal slab of triangular lattice under an external dc magnetic field. The applied magnetic field breaks the time-reversal symmetry of the three-dimensional system, and thus the original degeneracy point in k space, at which ...
Louch William E - - 2012
Following contraction of the heart, efficient relaxation (diastole) is essential for refilling the ventricles with blood. This review describes how ventricular relaxation is controlled by Ca(2+) homeostasis in cardiac muscle cells and how alterations in Ca(2+) cycling affect diastolic function in the normal and failing heart. These discussions illustrate that ...
Boin I F S F - - 2012
Renal insufficiency can be associated with poor long-term survival of liver transplant recipients. The objective of this study was to study renal insufficiency observed pretransplantation and its long-term impact after liver transplantation. We analyzed retrospectively an electronic database collected prospectively including transplant records from June 1994 to October 2010 using ...
Dodge Tonya - - 2012
This study applied aspects of the Theory of Reasoned Action and the Prototype/Willingness model to understand cognitions associated with the use of illegal performance-enhancing substances. There were two study objectives. One was to investigate whether the illegal-is-effective heuristic (i.e. belief that illegal performance-enhancing substances are more effective than legal performance-enhancing ...
Wojciechowski Filip - - 2012
Multiple 2-pyrenyl-C-nucleosides were incorporated into the center of a DNA duplex resulting in stable pyrene self-recognition and excimer formation. This helical pyrene array may find use in DNA-mediated charge transfer and in the creation of DNA-based sensors.
Tucker Ian M - - 2012
Small angle neutron scattering, zeta potential measurements, and dynamic light scattering have been used to investigate the adsorption of polymer-surfactant mixtures at the oil-water interface. The water-hexadecane interface investigated was in the form of small oil-in-water emulsion droplets stabilized by the anionic surfactant sodium dodecyl sulfate, SDS. The impact of ...
Yoder John H - - 2012
When a new student first begins to push flies, an immediate skill that must be learned is sorting the sexes. In Drosophila melanogaster several sexually dimorphic characters can be used to readily distinguish males from females including abdominal pigmentation, male sex combs and genital morphology. Another, often-overlooked, sexual dimorphism is ...
White Mary - - 2012
In recent years, the growth of interest in global health among medical students and residents has led to an abundance of short-term training opportunities in low-resource environments. Given the disparities in resources, needs and expectations between visitors and their hosts, these experiences can raise complex ethical concerns. Recent calls for ...
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