Search Results
Results 501 - 550 of 3887
< 6 7 8 9 10 11 12 13 14 15 16 >
Zwar Nicholas A NA University of New South Wales, Sydney, NSW, Australia. - - 2012
To evaluate a partnership model of care for patients with a diagnosis of chronic obstructive pulmonary disease (COPD). Cluster randomised controlled trial with blinded outcome assessment of 44 general practices in south-western Sydney comprising 451 people with a diagnosis of COPD, conducted between 2006 and 2009. Participants from intervention group ...
Zhu Z H - - 2012
We show that optical transmission of linearly polarized light through a plasmonic subwavelength metallic grating cascaded with a dielectric grating at a 45° angle to each other is asymmetric in opposite directions. A key characteristic of this asymmetric transmission is that the polarization of the transmitted light is changed. Simulation ...
Liemert André - - 2012
The three-dimensional radiative transfer equation is solved in the spatial frequency domain for modeling the light propagation due to a spatially modulated light source obliquely incident on a semi-infinite uniform medium. The dependence of the derived solution on the spatial frequencies as well as on position and direction is found ...
Xie Youzhuan - - 2012
A prospective, randomized clinical study was performed to determine whether unilateral pedicle screw fixation was comparable with bilateral fixation in 1- or 2-segment lumbar interbody fusion. One hundred eight patients with lumbar degenerative diseases were randomly assigned to the unilateral (n=56) or bilateral (n=52) pedicle screw fixation group. Interbody fusion ...
Silva S M - - 2012
Dysfunction of the liver after transplantation may be related to the graft size and ischemia/reperfusion (I/R) injury. N-Acetylcysteine (NAC) exerts beneficial effects on livers undergoing ischemia reperfusion. We sought to evaluate NAC modulation on reduced livers associated with I/R injury. Male C57BL/6 mice of 8 weeks of age were divided ...
Prates L C - - 2012
Pain induced by calcineurin inhibitors is a rare complication of unknown pathogenesis. We have reported herein a 7-year-old child who presented with abdominal pain, vomiting, and weight loss showing no significant findings after an extensive laboratory and imaging workup. After conversion from tacrolimus to sirolimus, there was complete resolution of ...
Kuba Hiroshi H Nagoya University Faculty of Medicine, Physiology, Tsurumai-cho 65, Showa-ku, Nagoya 466-8550, Japan. - - 2012
The axon initial segment (AIS) that separates axonal and somato-dendritic compartments is a highly specialised neuronal structure enriched with voltage-gated Na(+) channels and functions as the site of spike initiation in neurons. The AIS was once thought to be uniform and static in structure, but has been found to be ...
Russo Eleonora - - 2012
Hashimoto's thyroiditis (HT) is an autoimmune disorder characterized by the presence of specific antibodies and by a lymphocytic infiltration of the thyroid secreting inflammatory cytokines. Macrophages, lymphocytes and cytokines play a pivotal role in both development and progression of Th1-mediated autoimmune diseases, and a direct role in the destruction of ...
Amiraraghi Natasha - - 2012
The authors report a case of paraganglioma of the skull base presenting as nasal polyps. A 29-year-old patient presented with epistaxis and was found to have nasal polyps. The patient underwent a nasal polypectomy. After pathology showed an unusual appearance, the mass was subsequently excised endoscopically using radiofrequency coblation, and ...
Stephens Mary Ann Parris MA Department of Psychology, Kent State - - 2013
To investigate daily dietary adherence and diabetes-specific distress among older adults with type 2 diabetes mellitus (T2DM) as a function of spouses' diet-related support and diet-related control (persuasion and pressure) and whether these daily processes differ among couples who do and do not appraise responsibility for managing T2DM as shared. ...
Vaz-Luis Ines - - 2012
ABSTRACT: INTRODUCTION: In gene expression experiments, hormone receptor (HR)-positive/human epidermal growth factor-2 (HER2)-positive tumors generally cluster within the luminal B subset; whereas HR-negative/HER2-positive tumors reside in the HER2-enriched subset. We investigated whether the clinical behavior of HER2-positive tumors differs by HR status. METHODS: We evaluated 3,394 patients who presented to ...
Hansson Monika - - 2012
ABSTRACT: INTRODUCTION: Autoantibodies directed against citrullinated proteins/peptides (ACPA) are highly specific and predictive for the development of rheumatoid arthritis (RA). Different subgroups of RA patients, which have different prognosis and may require different treatments, are characterized by different autoantibody profiles. The objective of this study was to develop a microarray ...
Boyer Bret A - - 2012
To test 3 models that examine the relationship of posttraumatic stress (PTS), family functioning (FF), and level of spinal cord injury (SCI) to functional independence (FI) among patients with pediatric-onset SCI. Participants were 109 pediatric spinal cord injury patients, ages 11-24 years, from 2 surgical and rehabilitation hospitals. Data from ...
Giordano Mario M Pediatric Nephrology and Dialysis Unit, Ospedale Pediatrico Giovanni XXIII, Bari, Italy. - - 2012
Genetic mutations in complement components are associated with the development of atypical hemolytic uremic syndrome (aHUS), a rare disease with high morbidity rate triggered by infections or unidentified factors. The uncontrolled activation of the alternative pathway of complement results in systemic endothelial damage leading to progressive development of renal failure. ...
Kirkham James D - - 2012
The synthesis of a range of novel ynone trifluoroborates has been achieved, in a two-pot process from propargylic alcohols. These alkynes have been subsequently used in the formation of a range of pyrazole trifluoroborate salts via cyclization with hydrazines. The products are generated with high levels of regiocontrol and in ...
Hartman Z Z Department of Biochemistry, School of Medicine, West Virginia University, Morgantown, WV 26506, - - 2013
One of the causes of breast cancer is overexpression of the human epidermal growth factor receptor 2 (HER2). Enhanced receptor autophosphorylation and resistance to activation-induced downregulation have been suggested as mechanisms for HER2-induced sustained signaling and cell transformation. However, the molecular mechanisms underlying these possibilities remain incompletely understood. In the ...
Choi Hyun A - - 2012
Curcumin, a major constituent in rhizomes of Curcuma longa L., has shown various biological activities. It has widely been used as a food additive to provide potential health benefits. In the present study, we investigated changes in chemical stability and cytotoxic properties of curcumin and commonly-consumed over-the-counter (OTC) drugs including ...
Richardson Jason F - - 2012
Endoscopic access to the gastric remnant and pancreatobiliary tree is technically difficult after Roux-en-Y gastric bypass even when facilitated by the use of specialized techniques such as balloon enteroscopy and the use of overtubes. Furthermore, such techniques are not universally available at all medical centers. We describe a case series ...
Law L Matthew - - 2012
The anterior thalamus (AT) is anatomically interconnected with the hippocampus and other structures known to be involved in memory, and the AT is involved in many of the same learning and memory functions as the hippocampus. For example, like the hippocampus, the AT is involved in spatial cognition and episodic ...
Park Hyun Woo HW Department of Pharmacology, Brain Korea 21 Project for Medical Science, Yonsei University College of Medicine, Seoul 120-752, - - 2012
Many cystic fibrosis transmembrane conductance regulator (CFTR)-expressing epithelia secrete bicarbonate (HCO(3)(-))-containing fluids. Recent evidence suggests that defects in epithelial bicarbonate secretion are directly involved in the pathogenesis of cystic fibrosis, in particular by building up hyperviscous mucus in the ductal structures of the lung and pancreas. Pancreatic juice is one ...
Merriweather Nakia - - 2012
Percutaneous coronary intervention for acute coronary syndrome or non-ST-elevation myocardial infarction requires the use of potent oral and intravenous anti-platelet and antithrombin medications. Although these potent antithrombotic agents and regimens may increase the effectiveness of percutaneous coronary intervention, they are also generally associated with an increased risk of vascular access ...
Arnold Catherine K - - 2012
Abstract This qualitative study examines the support needs of adult siblings of people with developmental disabilities. A survey completed by 139 siblings of people with developmental disabilities captured the needs of adult siblings through 2 open-ended questions. A grounded theory approach was used, and the sibling responses anchored the analysis, ...
Engel Benjamin D - - 2012
The maintenance of flagellar length is believed to require both anterograde and retrograde intraflagellar transport (IFT). However, it is difficult to uncouple the functions of retrograde transport from anterograde, as null mutants in dynein heavy chain 1b (DHC1b) have stumpy flagella, demonstrating solely that retrograde IFT is required for flagellar ...
Cestier Isabelle - - 2012
We report on a chip scale parametric amplifier based on a GaInP photonic crystal waveguide. The amplifier operates with both pump and signal in the 1550 nm wavelength range and offers an on-chip gain of 11 dB (5 dB including the 6 dB coupling losses) when pumped at only 800 mW. It enables us, therefore, ...
Tyazhev Aleksey - - 2012
The orthorhombic biaxial crystal BaGa<sub>4</sub>S<sub>7</sub> has been employed in a 1064 nm pumped optical parametric oscillator generating <6  ns long idler pulses with energies as high as 0.5 mJ at 6.217 μm and average power of ∼50  mW at 100 Hz. Notwithstanding the relatively low nonlinearity, ∼3 times above threshold operation has been achieved at pump ...
Beck John D - - 2012
The purpose of this retrospective study was to examine pediatric supracondylar humerus fractures at a Level I trauma center. Data were analyzed to identify risk factors associated with closed reduction failure. Closed pediatric supracondylar humerus fractures that were treated at the authors' trauma center between October 1997 and January 2009 ...
Taha M O - - 2012
To study whether ischemic preconditioning (IPC) attenuated intestinal dysfunction caused by ischemia (I) and reperfusion (R), rats were underwent 60 minutes of I which was produced by occlusion of the superior mesenteric artery, and/or 120 minutes R. The IPC group had the I procedure previously stimulated for 5 minutes and ...
Abboud C S CS Serviço de Controle de Infecção Hospitalar e Seção Médica de Infectologia, Institute Dante Pazzanese de Cardiologia, São Paulo, Brazil. - - 2012
Mucormycosis is a rare but emerging fungal infection complicating solid organ transplantation (SOT), with a cumulative incidence of around 2% during the first year after SOT. The associated mortality rate is high, and surgical debridement is frequently required as part of the treatment along with antifungal therapy based mostly on ...
Jiang Yiling - - 2012
The introduction of routine infant vaccination against pneumococcal disease has resulted in a decreased overall invasive pneumococcal disease incidence in adults but also a change in invasive pneumococcal disease serotypes. This study aimed to assess the cost-effectiveness of 23-valent pneumococcal polysaccharide vaccine (PPV23) in Germany in this context. A population-based ...
Iguchi Hiroyoshi - - 2012
Abstract Conclusion: Most hematolymphoid malignancies in the head and neck were malignant lymphomas that most often occurred in sexagenarian men. Approximately 80% of them were B-cell lymphomas with a predominance of diffuse large B-cell lymphoma (DLBCL) in both nodal and extranodal sites. Our results were compatible with those in a ...
Rochelle Tina L - - 2012
The present study investigates illness perceptions of inflammatory bowel disease patients in an outpatient population, examining whether these illness perceptions are related to disease severity, quality of life and psychological adjustment. A cohort of 102 inflammatory bowel disease outpatients was prospectively enrolled on the study. The participants completed a questionnaire ...
Andujar-De Sanctis Ivonne L - - 2012
Intramolecular (13)C kinetic isotope effects were determined for the dimerization of methacrolein. Trajectory studies accurately predict the isotope effects and support an origin in Newton's second law of motion, with no involvement of zero-point energy or transition state recrossing. Atomic motion reaction coordinate diagrams are introduced as a way to ...
Fagan Jay - - 2012
The major goal of the present study was to examine the reciprocal and longitudinal associations between coparenting conflict and father engagement with children during the early childhood years. Using data from the Early Childhood Longitudinal Survey-Birth Cohort (N = 3600), the findings supported the hypothesis that father engagement at 9 ...
Pham Nam - - 2012
p53 is a tetrameric multi-domain protein that triggers the anti-cancer cellular response to stress. We have calculated a three-dimensional reconstruction of full-length human p53 in the absence of DNA using single particle electron microscopy. The reconstruction of DNA-free full-length p53 shows a square-shaped structure with four distinct domains and a ...
Wang Lei - - 2012
p-Hydroxybenzoic acid esters (parabens) and bisphenol A diglycidyl ether (BADGE) are widely present in personal care products, food packages and material coatings. Nevertheless, little is known about the occurrence of these compounds in indoor dust. In this study, we collected 158 indoor dust samples from the U.S., China, Korea, and ...
Greskowiak Janek - - 2012
Simple closed-form approximations are presented for calculating the steady-state groundwater age distribution in two-dimensional vertical cross sections of idealized fresh water lenses overlying salt water, for aquifers that are vertically semi-infinite and of finite thickness. The approximations are developed on the basis of existing one-dimensional analytical solutions for travel-time calculation ...
König Stefanie - - 2012
In Arabidopsis, the fatty acid moiety of sphingolipids is mainly α-hydroxylated. The consequences of a reduction in this modification were analysed. Mutants of both Fatty Acid Hydroxylase genes (AtFAH1 and AtFAH2) were analysed for sphingolipid profiles. To elucidate further consequences of the mutations, metabolic analyses were performed and the influence ...
Silva Raquel - - 2012
Microspheres of bovine serum albumin (BSA) and silk fibroin (SF) are produced by applying ultrasound in a biphasic system consisting of an aqueous protein solution and an organic solvent. The protein microspheres are dispersed in an aqueous media where the protein remains at the interface covering the organic solvent. This ...
McCormick Emily V - - 2012
OBJECTIVE:To assess physician attitudes regarding school-located adolescent vaccination and influenza vaccination.METHODS:From July through September 2010, a 20-item survey was mailed to 1337 practicing Colorado family physicians and pediatricians. Standard statistical methods were used to examine unadjusted and adjusted odds ratios of factors associated with physician support for school-located vaccination programs.RESULTS:Overall, ...
Khan D - - 2012
Tumor-suppressor protein p53, the 'guardian of the genome', is critical in maintaining cellular homeostasis and genomic stability. Earlier, we have reported the discovery of internal ribosome entry sites (IRESs) within the p53 mRNA that regulate the translation of the full length and its N-terminal-truncated isoform, ΔN-p53. Polypyrimidine tract-binding protein (PTB) ...
Janssen Eva - - 2012
OBJECTIVE: Evidence is accumulating for the importance of feelings of risk in explaining cancer preventive behaviours, but best practices for influencing these feelings are limited. The aim of this experimental study was to compare the effects of narrative and non-narrative risk communication about sunbed use on ease of imagination and ...
Delvadia Renish R - - 2012
Abstract Background: Inhaler orientation with respect to a patient's mouth may be an important variable determining the efficiency of aerosol lung delivery. The effect of insertion angle on regional deposition was evaluated for a series of inhalers using concurrent in vitro and computational fluid dynamics (CFD) analysis. Methods: Geometrically realistic ...
Pakula Andrea M - - 2012
Necrotizing fasciitis is a rare severe soft tissue infection that has historically been associated with high mortality. We sought to evaluate our experience with necrotizing fasciitis focusing on outcomes based on timing of operative intervention. Our study hypothesis was that delays in surgical management would negatively impact outcomes. Fifty-four patients ...
Nash David A - - 2012
Health is critical to human well-being. Oral health is an integral component of health. One is not healthy without oral health. As health is essential to human flourishing, it is important that an oral healthcare delivery system and workforce be developed and deployed which can help ensure all citizens have ...
Finley Daniel - - 2012
Protein modifications provide cells with exquisite temporal and spatial control of protein function. Ubiquitin is among the most important modifiers, serving both to target hundreds of proteins for rapid degradation by the proteasome, and as a dynamic signaling agent that regulates the function of covalently bound proteins. The diverse effects ...
Mehling I - - 2012
This review evaluates which conclusions can be drawn for the clinical daily routine in operative treatment of distal radius fractures, regarding the published biomechanical studies concerning implant systems within the last 10 years.After identification of 21 articles about biomechanical studies of implant systems for the treatment of distal radius fractures ...
Carlos Ruth C - - 2012
The Patient-Centered Outcomes Research Institute was created in response to a mandate to conduct comparative effectiveness research in clinical care to inform decision making. The institute will be funded by the Patient-Centered Outcomes Research Trust Fund, through congressional set-asides, and by Medicare and private health insurers, through a per beneficiary ...
Kaplan Peter W - - 2012
Genetic epilepsies with generalized spike-wave complexes (GSWCs) and encephalopathy triphasic waves (TWs) may resemble each other and have three phases per complex. Electroencephalographic (EEG) interpretation is subjective, and EEGers have noted "TWs" in cases labeled nonconvulsive status epilepticus (NCSE). Direct comparison of both wave forms under the same conditions is ...
Chistiakova Maria V - - 2012
Optical microcavities provide an intriguing platform for the development of low threshold microlasers based on nonlinear effects. Long photon lifetimes within the cavity translate to high circulating optical intensities, thereby reducing the lasing threshold. It is therefore possible to create lasers that can operate in complex environments. In the present ...
Kim Tae-Hoon - - 2012
The authors hypothesized that an image-free navigation system would be more accurate than postoperative 3-dimensional (3-D) reconstructed computed tomography (CT) for acetabular cup inclination and anteversion during total hip arthroplasty (THA) in an Asian population. Eighty-one THAs were performed in 72 patients using the OrthoPilot image-free navigation system (B. Braun ...
< 6 7 8 9 10 11 12 13 14 15 16 >