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Results 501 - 550 of 4408
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Xing Yan - - 2012
The active metabolite in the post-harvested biomass of zinc (Zn) and cadmium (Cd) hyperaccumulator Sedum alfredii Hance from phytoextraction is of great interest in China. The current study demonstrates that a salidroside-type metabolite can be yielded from the Zn/Cd hyperaccumulator S. alfredii biomass by means of sonication/ethanol extraction and macroporous ...
Iamsaard Sitthichai - - 2012
To examine the structure of the oviduct of the shrimp Penaeus monodon. The oviducts of P. monodon with three different major groups of ovarian development (Group (Gr.) 1: Stages I & V; Gr. 2: Stages II & III; and Gr. 3: Stage IV) were examined by light, transmission electron, and ...
Wang Hui-ying - - 2012
Chinese bayberry Myrica rubra is a very popular fruit in southeastern China. In spite of its wide consumption, no allergies to this fruit have been reported previously. Here we report on a 40-year-old woman suffering from anaphylaxis to Chinese bayberry fruit. Prick-prick skin tests revealed strong reactions to fresh Chinese ...
Matthews Karen A - - 2012
Poor sleep may play a role in insulin resistance and diabetes risk. Yet few studies of sleep and insulin resistance have focused on the important developmental period of adolescence. To address this gap, we examined the association of sleep and insulin resistance in healthy adolescents. Cross-sectional. Community setting in one ...
Ulman T Frances - - 2012
We compared sleep problems during pregnancy and sleep dissatisfaction 18 months after pregnancy in pregnant women with binge eating disorder (BED) symptoms and pregnant women without an eating disorder. Norwegian Mother and Child Cohort Study (MoBa). Data were gathered from 72,435 women. A total of 1,495 (2.1%) women reported having ...
Reeder Amy L - - 2012
Homozygous null mutation of the fibroblast growth factor receptor 2IIIb (Fgfr2IIIb) gene in mice results in 42% of embryos developing duodenal atresias. Retinaldehyde dehydrogenase 2 (Raldh2, a gene critical for the generation of retinoic acid) is expressed in the mouse duodenum during the temporal window when duodenal atresias form. Raldh2 ...
Dalla-Favera Riccardo - - 2012
The lymphoid tissues, including both the B and T cell lineages, are characterized by a unique level of biological complexity due to the anatomical organization of functionally distinct cell subpopulations and complex processes of genetic alteration required to generate immune responses. Not surprisingly, this physiological diversity and complexity is mirrored ...
Kridel Robert - - 2012
The hallmark t(14;18)(q32;q21) in follicular lymphoma (FL) results in constitutive overexpression of the BCL2 protein, allowing B cells to abrogate the default germinal center apoptotic program. Most tumors are characterized by recurrent secondary genetic alterations including genomic gains, losses, and mutations, some providing a growth advantage, including alterations in MLL2, ...
Küppers Ralf - - 2012
Hodgkin lymphoma (HL), a B cell-derived cancer, is one of the most common lymphomas. In HL, the tumor cells--Hodgkin and Reed-Sternberg (HRS) cells--are usually very rare in the tissue. Although HRS cells are derived from mature B cells, they have largely lost their B cell phenotype and show a very ...
Chen Shi-chao - - 2012
Total dissolved gas (TDG) supersaturation caused by dam sluicing can result in gas bubble trauma (GBT) in fish and threaten their survival. In the present study, Chinese suckers (Myxocyprinus asiaticus Bleeker) were exposed to TDG supersaturated water at levels ranging from 120% to 145% for 48 h. The median lethal ...
Fernandez Jose-Maria - - 2012
Biomedical innovation has become riskier, more expensive and more difficult to finance with traditional sources such as private and public equity. Here we propose a financial structure in which a large number of biomedical programs at various stages of development are funded by a single entity to substantially reduce the ...
Pilliod Rachel A - - 2012
We sought to evaluate the risk of intrauterine fetal death (IUFD) in small-for-gestational-age (SGA) fetuses. We analyzed a retrospective cohort of all births in the United States in 2005, as recorded in a national database. We calculated the risk of IUFD within 3 sets of SGA threshold categories as well ...
Heffner Jaimee L - - 2012
There is a high prevalence of smoking among individuals with bipolar disorder, yet there have been few efforts to identify potential contributing factors as a means of improving prevention and treatment approaches. The goal of this study was to examine the association between impulsivity and the initiation or maintenance of ...
Asghari Golaleh - - 2012
The aim of this study was to investigate the ability of diet quality indices in predicting obesity and abdominal obesity in a population in nutrition transition. This study explored the association of the Mediterranean Diet Scale (MDS), Healthy Eating Index-2005 (HEI-2005), and Diet Quality Index-International (DQI-I) with body mass index ...
Iannuzzi James C - - 2012
We hypothesized that patients referred for the evaluation and management of primary hyperparathyroidism (pHPT) often do not have pHPT and that they may be harmed by unwarranted parathyroidectomy (PTX). We reviewed all patients who were referred to our endocrine surgery practice between 2008 and 2011 with International Classification of Diseases, ...
Lionaki Sophia - - 2012
To compare the usefulness of 3 currently used classification systems in predicting the outcomes of treatment resistance, disease relapse, end-stage renal disease (ESRD), and death in patients with antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV). Three classification systems were applied to 502 patients with biopsy-proven AAV: 1) the Chapel Hill Consensus ...
Wolfe-Christensen Cortney - - 2012
To assess rates of psychosocial difficulties in children seen in a pediatric urology clinic to determine whether all patients should be screened for psychosocial problems, and to use standardized measures to determine whether the severity of voiding dysfunction and/or enuresis in children is related to their degree of psychosocial difficulties. ...
Vanderbilt Douglas L - - 2012
To identify risk factors for cerebral lesions among survivors of twin-twin transfusion syndrome treated with laser surgery. A multilevel regression analysis examined risk factors for neonatal cerebral lesions identified by imaging. Imaging was routine in "high-risk survivors," defined as those delivered at <32 weeks' gestation, and by clinical indications if ...
Shields Wendy C - - 2012
This study focuses on parental report of exposure to dogs and highlights the potential for using a computer kiosk in an urban pediatric emergency department to increase knowledge around dog bite safety. Nine hundred one parents of young children completed a kiosk assessment and received a report that contained information ...
Kubicek Katrina - - 2012
This study was designed to develop a descriptive profile of parents and caregivers who bring their children to the emergency department (ED) for nonurgent issues and to explore the reasons for presenting to an urban hospital pediatric ED for nonurgent conditions. Such work is necessary to develop effective interventions. A ...
Nixon Abigail F - - 2012
The purpose of this study was to evaluate the effectiveness of the probiotic Lactobacillus GG (LGG) in reducing the duration of acute infectious diarrhea in the pediatric emergency department. We conducted a double-blind, randomized controlled trial of children 6 months to 6 years presenting to the pediatric emergency department with ...
Ramsawh Holly J - - 2012
Adolescence is a time of increasing risk for some anxiety disorders. Scant data exist on adolescent anxiety in emergency department (ED) settings. We sought to characterize select clinical characteristics and health care use associated with anxiety disorders in a pediatric ED. We screened a convenience sample of 100 adolescent-parent dyads ...
Tichauer K M - - 2012
The quantification of tumor molecular expression in vivo could have a significant impact for informing and monitoring emerging targeted therapies in oncology. Molecular imaging of targeted tracers can be used to quantify receptor expression in the form of a binding potential (BP) if the arterial input curve or a surrogate ...
Guilcher Sara J T - - 2013
To understand the journey of care in the prevention and management of secondary health conditions (SHCs) following spinal cord injury (SCI). This was a case study design with 'Ontario' as the case. The Network Episode Model was used as the conceptual framework. Data sources included in depth interviews with persons ...
Jiang Peng - - 2012
We have previously established that CAST/EiJ (CAST) mice differ from normal mice, such as C57BL/6J (B6), in the timing of wheel-running onset relative to light/dark cycles. These mice provide an animal model for studies of the genetic and neurobiological basis for circadian phase misalignment in humans. Neither differences in endogenous ...
Goodmanson Nicholas W - - 2012
Injured elderly patients experience high rates of undertriage to trauma centers (TCs) whereas debate continues regarding the age defining a geriatric trauma patient. We sought to identify when mortality risk increases in injured patients as the result of age alone to determine whether TC care was associated with improved outcomes ...
Richman Ilana B IB Stanford University, Stanford, California, - - 2012
African Americans, East Asians, and Hispanics with systemic lupus erythematosus (SLE) are more likely to develop renal disease than are SLE patients of European descent. This study was undertaken to investigate whether European genetic ancestry protects against the development of lupus nephritis, with the aim of exploring the genetic and ...
Butterworth Karl T KT Centre for Cancer Research and Cell Biology, Queen's University Belfast, Belfast, UK. - - 2012
The relative biological effectiveness (RBE) of passive scattered (PS) and pencil beam scanned (PBS) proton beam delivery techniques for uniform beam configurations was determined by clonogenic survival. The radiobiological impact of modulated beam configurations on cell survival occurring in- or out-of-field for both delivery techniques was determined with intercellular communication ...
Grant Marcia M City of Hope National Medical Center, Beckman Research Institute, Duarte, CA, USA. - - 2012
For some patients diagnosed with rectal cancer, surgery will involve the creation of a temporary or permanent ostomy. When the colostomy is located in the sigmoid or descending colon, regulation of fecal output can occur through irrigation, a procedure that involves instilling fluid into the bowel to flush out gas ...
Atakan Z Z Section of Neuroimaging, Department of Psychosis Studies, Institute of Psychiatry, King's College London, London, UK. - - 2013
Cannabis can induce transient psychotic symptoms, but not all users experience these adverse effects. We compared the neural response to Δ9-tetrahydrocannabinol (THC) in healthy volunteers in whom the drug did or did not induce acute psychotic symptoms. Method In a double-blind, placebo-controlled, pseudorandomized design, 21 healthy men with minimal experience ...
Kothari R R Behavioural and Brain Sciences Unit, Institute of Child Health, University College London, UK. - - 2013
There is a large body of evidence indicating that eating disorders (EDs) are characterized by particular neuropsychological profiles. We aimed to further explore whether impairments in neuropsychological functioning previously found in ED groups are present prior to onset, or are secondary to the disorder. Method This is the first study ...
Zhong Quincy Q Section of Reproductive Endocrinology, Department of Obstetrics and Gynecology; and Institute of Molecular Medicine and Genetics, Neuroscience Program, Georgia Health Sciences University, Augusta, Georgia 30912, - - 2012
Turner syndrome (TS) is a complex developmental disorder in individuals with short stature who possess a 45,X cell line, with or without mosaicism. Because the single X chromosome is maternally derived in 80% of patients, the genesis of the 45,X karyotype is due to instability of the Y chromosome leading ...
Guvenc Pelin P Department of Electrical and Computer Engineering, Southern Illinois University, Edwardsville, IL 62025, - - 2013
Blue-gray ovoids (B-GOs), a critical dermoscopic structure for basal cell carcinoma (BCC), offer an opportunity for automatic detection of BCC. Due to variation in size and color, B-GOs can be easily mistaken for similar structures in benign lesions. Analysis of these structures could afford accurate characterization and automatic recognition of ...
Ebrahimi-ghiri Mohaddeseh M Department of Biology, Faculty of Basic Sciences, Tarbiat Moalem (Kharazmi) University, Tehran, - - 2012
Several investigations have indicated that cholestasis decreases opioid receptor expression in the brain following increased opioidergic neurotransmission. The opioidergic system plays an important role in regulation of reward circuits that may be produced via dopamine-dependent mechanisms. It has been suggested that the dopaminergic system of the nucleus accumbens is necessary ...
Gaidano Gianluca G Division of Hematology, Department of Translational Medicine, Amedeo Avogadro University of Eastern Piedmont, Novara, - - 2012
Chronic lymphocytic leukemia (CLL) is the most common leukemia in adults. Here, we highlight important genetic alterations that contribute to tumorigenesis, clinical progression, and chemorefractoriness of CLL. All CLLs share a common gene expression profile that suggests derivation from antigen-experienced B cells, a model supported by frequent B cell receptor ...
Bauer Rebecca N RN Curriculum in Toxicology, Gillings School of Public Health, The University of North Carolina at Chapel Hill, Chapel Hill, NC, - - 2012
The leading cause of asthma exacerbation is respiratory viral infection. Innate antiviral defense pathways are altered in the asthmatic epithelium, yet involvement of inflammasome signaling in virus-induced asthma exacerbation is not known. This study compared influenza-induced activation of inflammasome and innate immune signaling in human bronchial epithelial cells from volunteers ...
Yu Shibin - - 2012
ABSTRACT: BACKGROUND: Estrogens play an important role in modulating the morphology and function of temporomandibular joints (TMJs), which is suggested to act via estrogen receptors (ERs). The present study was to investigate the expression of aggrecan, collagen type II (Col II), Col X, aromatase, ERalpha and ERbeta in degenerative changes ...
van 't Erve O M J - - 2012
Spin manipulation in a semiconductor offers a new paradigm for device operation beyond Moore's law. Ferromagnetic metals are ideal contacts for spin injection and detection, but the intervening tunnel barrier required to accommodate the large difference in conductivity introduces defects, trapped charge and material interdiffusion, which severely compromise performance. Here, ...
Sandberg Richard L - - 2012
Carrier multiplication (CM) is the process in which absorption of a single photon produces multiple electron-hole pairs. Here, we evaluate the effect of particle shape on CM efficiency by conducting a comparative study of spherical nanocrystal quantum dots (NQDs) and elongated nanorods (NRs) of PbSe using a time-resolved technique that ...
Xu Jianfeng - - 2012
Prostate cancer risk-associated variants have been reported in populations of European descent, African-Americans and Japanese using genome-wide association studies (GWAS). To systematically investigate prostate cancer risk-associated variants in Chinese men, we performed the first GWAS in Han Chinese. In addition to confirming several associations reported in other ancestry groups, this ...
Lenting P J - - 2012
Von Willebrand factor (VWF) is a protein best known from its critical role in hemostasis. Indeed, any dysfunction of VWF is associated with a severe bleeding tendency known as von Willebrand disease (VWD). Since the first description of the disease by Dr. Erich von Willebrand in 1926, remarkable progress has ...
Kotani Yasuhiro - - 2012
From 2005 to 2011, 23 of 178 (12.9%) patients with venoarterial (VA) extracorporeal membrane oxygenation (ECMO) had left atrial (LA) decompression to help improve left ventricular (LV) function, LA/LV dilatation, and/or lung edema. LA decompression was achieved with LA cannulation (n = 16), surgically created adjustable atrial septal defect (n ...
Pahari Dipak R - - 2012
A minimized perfusion circuit (MPC) has proven to be superior to the conventional circulatory perfusion bypass (CCPB) as it reduces the blood-material interaction and hemodilution. Until now not much is known about impact these different perfusion systems have on the brain. The objective of this study is to determine carnosinase ...
Barrera D - - 2012
The possible epigenomic effect of oviductal fluid on expression of DNA methyltransferase (DNMT) genes was examined in early bovine embryos (4-cell stage). Real-time quantitative PCR was performed to determine the relative expression of DNMT1, DNMT3a and DNMT3b transcripts in embryos cultured in vitro in the presence or absence of oviductal ...
Reichert M - - 2012
Viral haemorrhagic septicaemia (VHS), caused by the novirhabdovirus viral haemorrhagic septicaemia virus (VHSV), causes significant economic problems to European rainbow trout, Oncorhynchus mykiss (Walbaum), production. The virus isolates can be divided into four distinct genotypes with additional subgroups. The main source of outbreaks in European rainbow trout farming is sublineage ...
Adhikari Sajag - - 2012
microRNAs (miRNAs) are short, non-coding regulatory RNAs that play crucial roles in plant development and responses to environmental cues. Reliable and accurate measurements of miRNA abundance by Northern hybridization and qPCR have significantly contributed to our understanding of miRNA function. Two most commonly used methods to generate cDNAs for miRNA ...
Pieters J J P M - - 2012
OBJECTIVE: Incidental findings in prenatal diagnostic testing may or may not have clear prognostic significance for the phenotype. We studied experts' opinions of the benefit and disadvantage of an incidental prenatal diagnosis of a sex chromosomal aneuploidy (SCA). METHODS: We interviewed 16 experts in the field of counseling and treatment ...
Chen Wen-Xin - - 2012
We report herein that amides are excellent N-sources in the NHC-Pd(II)-Im complex 1 catalyzed amination of aryl chlorides. In the presence of KOtBu, various aryl chlorides and amides can react smoothly to give the corresponding aminated products in moderate to almost quantitative yields at room temperature within 6 h.
Chen Ying-Jia - - 2012
To evaluate the effect of glucose and fructose on the glycation of β-lactoglobulin (β-Lg) in intermediate moisture food (IMF), model systems consisted of β-Lg, glucose/fructose/sorbitol, glycerol and water were established. All systems were stored at 25 and 35 °C for two months. The progress of Maillard reaction and the mass ...
Young J - - 2012
BackgroundPeople with type 1 diabetes may find diabetic control more difficult when working shifts.AimsTo investigate the proportion of people with type 1 diabetes in employment undertaking shift work and diabetic control as assessed by glycosylated haemoglobin (HbA1c) among individuals undertaking shift work compared to those not doing so.MethodsA postal questionnaire ...
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