Search Results
Results 401 - 450 of 2840
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Meyer Jeffrey H - - 2012
Neurochemical imaging is frequently applied to measure markers of pathological change so as to understand mechanisms that create symptoms of major depressive disorder. For example, indices of greater monoamine oxidase A(MAO-A) level, particularly in the prefrontal and anterior cingulate cortex, are associated with depressed mood states, and high-risk states for ...
Kuper-Hommel Marion J J - - 2012
Primary B-cell lymphoma of the testis, breast and thyroid are rare and data concerning cytogenetic aberrations at these extranodal sites are scarce. We examined the presence of extranodal marginal zone lymphoma-associated translocations, t(11;18)(q21;q21), t(1;14)(p22;q32), t(14;18)(q32;q21), t(3;14)(p14.1;q32) and numerical aberrations of chromosomes 1, 3, 12 and 18 by fluorescence in situ ...
Gumieiro David N - - 2012
The aim of the present study was to evaluate the Mini Nutritional Assessment (MNA), the Nutritional Risk Screening (NRS) 2002 and the American Society of Anesthesiologists Physical Status Score (ASA) as predictors of gait status and mortality 6 months after hip fracture. A total of eighty-eight consecutive patients over the ...
Wang Hui - - 2012
In this work, a simple and fast sample pretreatment method was proposed for determination of steroid hormones in fish tissues by coupling dynamic microwave-assisted extraction with salting-out liquid-liquid extraction. The steroid hormones were successively extracted with acetonitrile and water under the action of microwave energy. Subsequently, the extract was separated ...
Christiansen A E AE Department of Biochemistry and Molecular Biology, The University of Texas M. D. Anderson Cancer Center, Genes & Development Graduate Program, 1515 Holcombe Boulevard-Unit 1000, Houston, TX 77030, - - 2013
Hedgehog (Hh) signaling is important for development and homeostasis in vertebrates and invertebrates. Ligand-independent, deregulated Hh signaling caused by loss of negative regulators such as Patched causes excessive cell proliferation, leading to overgrowth in Drosophila and tumors in humans, including basal-cell carcinoma and medulloblastoma. We show that in Drosophila deregulated ...
Chou Sharon H - - 2012
We introduce a model for the effect of cesium adsorbates on the work function of transition metal surfaces. The model builds on the classical point-dipole equation by adding exponential terms that characterize the degree of orbital overlap between the 6s states of neighboring cesium adsorbates and its effect on the ...
Atrei Andrea - - 2012
Ultrathin films of TiO(2) were grown on Ag(100) by evaporation of titanium in the presence of O(2) at a pressure in the 10(-4) Pa range and annealing at 770 K. The composition of the deposited films was monitored by XPS and LEIS. The morphology at the nanometric scale of the TiO(2) films ...
Astray Gonzalo - - 2012
In this article, an artificial neural network to predict the flash point of 95 esters was implemented. Four variables were used for its development. A neural network with 4-5-8-5-1 topology was encountered to gain the best agreement of the experimental results with those predicted (square correlation coefficient (R(2) ) and ...
Akasbi Yousra - - 2012
"Classic" Kaposi's sarcoma (CKS) not related to HIV is a multifocal angioproliferative neoplasm that is linked to human herpesvirus. CKS is a cutaneous cancer frequently occurring with an indolent course. However, it can compromise the quality of life by causing pain, disfigurement and functional disability. For this reason, the main ...
D'Urso Luisa - - 2012
Physicochemical properties of the graphene-water interface have been investigated to scrutinize the perturbations with respect to the graphene-air interface, in terms of changes in optical and vibrational spectra, as well as in the 3D network of water. Experimental investigations were carried out using Raman spectroscopy and laser scanning confocal microscopy, ...
Nomura Kazuhiro - - 2012
Obesity is a major risk factor for sleep-disordered breathing (SDB). However, many Japanese subjects with diabetes are less obese despite compared with Caucasian. We evaluated the relationship between SDB and clinical characteristics other than obesity, especially in relation to cardiac autonomic neuropathy (CAN) in Japanese subjects with diabetes. The study ...
Andersen F H - - 2012
BACKGROUND: The number of elderly (≥ 80 years) will increase markedly in Norway over the next 20 years, increasing the demand for health-care services, including intensive care. The aims of this study were to see if intensive care unit (ICU) resource use and survival are different for elderly ICU patients than ...
Chiu Yvonne E YE Division of Pediatric Dermatology, Department of Dermatology, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, USA. - - 2013
Piebaldism is a rare genodermatosis caused by KIT mutations. We report the case of a 5-year-old boy who had the white forelock and leukoderma of piebaldism, but the presence of many café-au-lait macules and axillary and inguinal freckling complicated the diagnosis. Patients with similar cutaneous findings have been previously reported, ...
Wiig Jared A JA Department of Molecular Biology and Biochemistry, University of California, Irvine, CA 92697-3900, - - 2012
The active site of nitrogenase, the M-cluster, is a metal-sulfur cluster containing a carbide at its core. Using radiolabeling experiments, we show that this carbide originates from the methyl group of S-adenosylmethionine (SAM) and that it is inserted into the M-cluster by the assembly protein NifB. Our SAM cleavage and ...
Robinson Katie - - 2012
Abstract The aim of this study was to investigate the discourses used by people with chronic pain. Using qualitative interview data from five Irish people with a variety of chronic pain conditions, Foucauldian discourse analysis was undertaken to identify the discourses in operation in participants' accounts. Three discourses were identified: ...
Price Richard W - - 2012
Central nervous system (CNS) HIV infection is a nearly universal facet of systemic infection. Although antiretroviral therapy is generally effective in suppressing this infection and reducing its severe complications, reports of continued neurological abnormalities have questioned whether treatment developed for systemic efficacy is optimized for CNS infection. Shikuma et al. ...
Minen Federico - - 2012
Abstract Objective. Etiologies of acute pancreatitis (AP) in children are more variable than in adults, including drugs, traumas, infections and multisystem disorders as well as biliary anomalies. While causes of pancreatitis have been extensively analyzed, different series reported different causes. The aims of this study were: 1) to assess the ...
Chiarugi Alberto - - 2012
NAD is a vital molecule in all organisms. It is a key component of both energy and signal transduction - processes that undergo crucial changes in cancer cells. NAD(+)-dependent signalling pathways are many and varied, and they regulate fundamental events such as transcription, DNA repair, cell cycle progression, apoptosis and ...
Venditti Rossella R Telethon Institute of Genetics and Medicine, Naples, - - 2012
Newly synthesized proteins exit the endoplasmic reticulum (ER) via coat protein complex II (COPII) vesicles. Procollagen (PC), however, forms prefibrils that are too large to fit into typical COPII vesicles; PC thus needs large transport carriers, which we term megacarriers. TANGO1 assists PC packing, but its role in promoting the ...
El Bakali Jamal - - 2012
Further to our earlier work on a the 4-oxo-1,4-dihydropyridine, we describe herein our strategy to get access to potent selective CB2 receptor agonists. Thus, we designed and synthesized twenty nine compounds, evaluated on both hCB1 and hCB2 cannabinoid receptors and assessed eleven of them in the TNBS-induced colitis model in ...
Rodríguez-Oseguera A G - - 2012
Stenocereus quevedonis ('pitire') is a columnar cactus endemic to central Mexico, grown for its edible fruit. Phenology, pollination biology and behaviour of flower visitors of this species were compared in six conserved and disturbed sites, hypothesising that: (i) pitire pollination is self-incompatible, requiring animal vectors; (ii) higher incidence of radiation ...
Baumel-Alterzon Sharon - - 2012
Adaptation to nutritional changes is a key feature for successful survival of a pathogen within its host. The protozoan parasite Entamoeba histolytica normally colonizes the human colon and in rare occasions, this parasite spread to distant organs, such as the liver. E. histolytica obtains most of its energy from the ...
Wang C - - 2012
In our previous works, we demonstrated that human neural stem cells (NSCs) transduced with the cytosine deaminase (CD) gene showed remarkable 'bystander killer effect' on glioma and medulloblastoma cells after administration of the prodrug 5-fluorocytosine (5-FC). In addition, herpes simplex virus thymidine kinase (TK) is a widely studied enzyme used ...
Glatter Timo - - 2012
The complete and specific proteolytic cleavage of protein samples into peptides is crucial for the success of every shotgun LC-MS/MS experiment. In particular, popular peptide based label-free and targeted mass spectrometry approaches rely on efficient generation of fully cleaved peptides to assure accurate and sensitive protein quantification. In contrast to ...
Liu Gang - - 2012
Owing to their unique physical and chemical properties, magnetic iron oxide nanoparticles have become a powerful platform in many diverse aspects of biomedicine, including magnetic resonance imaging, drug and gene delivery, biological sensing, and hyperthermia. However, the biomedical applications of magnetic iron oxide nanoparticles arouse serious concerns about their pharmacokinetics, ...
Hwang Suk-Won - - 2012
A remarkable feature of modern silicon electronics is its ability to remain physically invariant, almost indefinitely for practical purposes. Although this characteristic is a hallmark of applications of integrated circuits that exist today, there might be opportunities for systems that offer the opposite behavior, such as implantable devices that function ...
Wright Belinda K BK School of Science and Health, University of Western Sydney, Hawkesbury, New South Wales, - - 2012
Analysis of the cellular distributions of coenzymes including NADH may aid in understanding a cells metabolic status. We altered serum concentration (0, 2, and 10%) to induce living myoblast cells to undergo the early stages of differentiation. Through microscopy and phasor-FLIM, we spatially mapped and identified variations in the distribution ...
Hirano Stefanie A - - 2012
  To review the literature on atopic dermatitis (AD) clinical trials published in the United States between 2000 and 2009 to examine the representation of racial and ethnic minorities in those trials and determine the extent to which investigators reported on demographic variables and performed a subanalysis. A PubMed search ...
Steubl Dominik - - 2012
Abstract Objective. BK virus (BKV)-induced viraemia after renal transplantation can be associated with severe impairment of graft function. This study evaluated possible risk factors for BKV replication and examined the outcomes following various currently used treatment approaches. Material and methods. Fifty-seven renal transplant recipients with BKV viraemia were retrospectively compared ...
Inaba Toshiro - - 2013
Non-invasive assessment of volume and function on the right ventricle (RV) for pulmonary hypertension (PH) is limited. Patients with PH (n=23) underwent 3-dimensional (D) echocardiography (3DECHO), with cardiac magnetic resonance imaging to confirm its precision, and right heart catheterization. On linear regression analysis the RV end-systolic volume index (ESVI) was ...
Boiocchi Leonardo - - 2012
Primary myelofibrosis is a type of chronic myeloproliferative neoplasm characterized by progressive bone marrow failure with worsening cytopenia and in a subset of patients, progression to acute leukemia. Published data in patients with myelodysplastic syndromes have shown that the development of monocytosis in the course of myelodysplastic syndromes is associated ...
Henderson Russell - - 2012
Particle facilitated transport is a key mechanism of phosphorus (P) loss in agroecosystems. We assessed contributions of colloid and nanoparticle-bound P (nPP; 1 nm - 415 nm) to total P released from grassland soils receiving bi-annual poultry litter applications since 1995. In laboratory incubations, soils were subjected to 7 days ...
Meydan C - - 2012
What is already known about this subject? Obesity is rising among children and adolescents in Israel and as a global trend. Obesity during adolescence correlates to morbidity in adulthood. Socio-demographic and ethnic factors are risk modifiers for obesity. What this study adds? Temporal trends of obesity in adolescents in a ...
Rutter Michael - - 2012
Background:  It is a universal finding that there is huge heterogeneity in people's responses to all kinds of stress and adversity. Resilience is an interactive phenomenon that is inferred from findings indicating that some individuals have a relatively good outcome despite having experienced serious adversities. Methods:  Resilience can only be ...
Iwase T - - 2012
To compare the development of posterior capsule opacification (PCO) for idiopathic epi-retinal membrane cases between 20- and 23-gauge phacovitrectomy. Cataract surgery of phacoemulsification with the SA60AT implantation and 20- or 23-gauge vitrectomy was performed for 20 patients in both groups. Cataract surgery alone was performed for 50 patients as the ...
Kubo Takashi - - 2012
For the practical use of activated carbon (AC) as an adsorbent of CH(4) , tightly packed monoliths with high microporosity are supposed to be one of the best morphologies in terms of storage capacity per apparent volume of the adsorbent material. However, monolith-type ACs may cause diffusion obstacles in adsorption ...
Taylor Jeanette J Department of Psychology, Florida State University, Tallahassee, FL 32306-4301, USA. - - 2013
Childhood behavioral disorders including conduct disorder (CD), oppositional defiant disorder (ODD), and attention-deficit/hyperactivity disorder (ADHD) often co-occur. Prior twin research shows that common sets of genetic and environmental factors are associated with these various disorders and they form a latent factor called Externalizing. The developmental propensity model posits that CD ...
Ofek Efrat - - 2012
We previously described restrictive allograft syndrome as a form of chronic lung allograft dysfunction, demonstrating restrictive pulmonary function decline. However, the histopathological correlates of restrictive allograft syndrome have yet to be satisfactorily described. We hypothesized that pulmonary pleuroparenchymal fibroelastosis, as has recently been described in bone marrow transplant recipients, may ...
Learoyd P - - 2012
Although there are a number of descriptions of 'blood infusion' in antiquity, it was the publication of the discovery of the circulation of blood in 1628 by William Harvey and the work of Christopher Wren and Robert Boyle in 1663 on the infusion of different materials into dogs that paved ...
Brown Ashley C - - 2012
Increased tissue stiffness and epithelial to mesenchymal transitions (EMT) are two seemingly discrete hallmarks of fibrotic diseases. Despite recent findings highlighting the influence of tissue mechanical properties on cell phenotype, it remains unclear what role increased tissue stiffness has in the regulation of previously reported fibronectin-mediated EMT associated with pulmonary ...
Polestshuk Pavel M - - 2012
The approach for the integration over a region covered by zero-flux surface is described. This approach based on the surface triangulation technique is efficiently realized in a newly developed program TWOE. The elaborated method is tested on several atomic properties including the source function. TWOE results are compared with those ...
Hao Pengfei - - 2012
The reactions of LAlH(2) (L = HC(CMeNAr)(2), Ar = 2,6-iPr(2)C(6)H(3)) () with diphenylsilanediol, phenylphosphonic acid, diphenylphosphinic acid, and pyrocatechol afford compounds with the Al-O-X (X = Si, P, C) motif of composition [LAl(μ-O)](2)Si(Ph)(2) (), [LAl(μ-O)](2)PO(Ph) (), LAl[OPO(Ph)(2)](2) (), and LAl(μ-O)(2)(o-C(6)H(4)) (), respectively. Compound contains the Al-O-Si-O-Al heterotrimetallic dioxide chain. Compound ...
Del Principe Domenico - - 2012
Fibrotic disorders are multistage progressive processes that often arise from different causes and are commonly associated with chronic inflammation. Excessive deposition of extracellular matrix is the hallmark of many fibrotic diseases. This may be due to an excess of fibroblast recruitment and activation as well as to their differentiation in ...
Duan Xiaopin - - 2012
Nanoparticles have many potential applications in tumor therapy. Systemically administered nanoparticles should remain in circulation for a long time to increase their accumulation in targeted tissues before being cleared by the reticuloendothelial system, and be effectively internalized by the targeted cells, which can be influenced significantly by the physicochemical characteristics ...
Croft Alison - - 2012
Background: Agoraphobia is disabling and clients find it hard to access effective treatment. Aims: This paper describes the development of an inexpensive service, delivered by trained volunteers in or near the client's own home. Method: We describe the development of the service, including selection, training and supervision. Outcomes were evaluated ...
Zhen Ying - - 2012
Numerous insects have independently evolved the ability to feed on plants that produce toxic secondary compounds called cardenolides and can sequester these compounds for use in their defense. We surveyed the protein target for cardenolides, the alpha subunit of the sodium pump, Na(+),K(+)-ATPase (ATPα), in 14 species that feed on ...
Chrzanowska Maria - - 2012
Summary Several studies have documented increased prevalence of overweight and obesity in inhabitants of rural regions, but determinants of their prevalence are complex and not always in one direction. The aim of this study was to estimate both the prevalence and extent of overweight and obesity among rural girls in ...
Esmat Samia M - - 2012
Laser-assisted hair removal causes miniaturization of hair shafts which are the principal contributors to inflammation in acne keloidalis nuchae (AKN). To assess the efficacy of hair reduction by long pulsed Nd-YAG laser as a therapeutic modality for AKN. This interventional pilot trial included 16 patients with AKN who received 5 ...
Ball Liam T - - 2012
Biaryls (two directly connected aromatic rings, Ar(1)-Ar(2)) are common motifs in pharmaceuticals, agrochemicals, and organic materials. Current methods for establishing the Ar(1)-Ar(2) bond are dominated by the cross-coupling of aryl halides (Ar(1)-X) with aryl metallics (Ar(2)-M). We report that, in the presence of 1 to 2 mole percent of a ...
Mohiyeddini Changiz - - 2012
Behavioural coping strategies represent a key means by which people regulate their stress levels. Attention has recently focused on the potential role in coping of 'displacement behaviour' - activities such as scratching, lip biting and face touching. Increased levels of displacement behaviour are associated with feelings of anxiety and stress; ...
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